ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KHLDIHDK_00001 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KHLDIHDK_00002 5.94e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KHLDIHDK_00003 2.76e-257 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHLDIHDK_00004 3.41e-107 - - - S - - - Protein of unknown function (DUF721)
KHLDIHDK_00005 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHLDIHDK_00006 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHLDIHDK_00007 1.49e-89 - - - S - - - Transmembrane domain of unknown function (DUF3566)
KHLDIHDK_00008 1.44e-232 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
KHLDIHDK_00009 5.95e-14 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
KHLDIHDK_00010 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
KHLDIHDK_00011 1.01e-262 - - - V - - - VanZ like family
KHLDIHDK_00012 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KHLDIHDK_00013 3.64e-252 - - - S - - - Psort location CytoplasmicMembrane, score
KHLDIHDK_00016 7.27e-159 - - - S ko:K07043 - ko00000 Protein of unknown function DUF45
KHLDIHDK_00018 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
KHLDIHDK_00019 4.45e-109 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KHLDIHDK_00020 5.81e-306 - - - P ko:K03699 - ko00000,ko02042 Transporter associated domain
KHLDIHDK_00021 4.77e-270 - - - S - - - AAA ATPase domain
KHLDIHDK_00022 3.82e-157 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
KHLDIHDK_00023 1.68e-138 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
KHLDIHDK_00024 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
KHLDIHDK_00025 0.0 - 5.1.3.2 - GM ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 ADP-glyceromanno-heptose 6-epimerase activity
KHLDIHDK_00026 6.99e-212 - - - - - - - -
KHLDIHDK_00027 7.4e-127 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2194)
KHLDIHDK_00028 4.77e-265 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2194)
KHLDIHDK_00029 0.0 - - GT4 M ko:K21011 ko02025,map02025 ko00000,ko00001,ko01003 Domain of unknown function (DUF3492)
KHLDIHDK_00030 0.0 - - - S ko:K21012 ko02025,map02025 ko00000,ko00001 Putative exopolysaccharide Exporter (EPS-E)
KHLDIHDK_00031 0.0 - - - M ko:K06330 - ko00000 CotH kinase protein
KHLDIHDK_00032 1.93e-203 - - - P - - - VTC domain
KHLDIHDK_00033 4.92e-142 - - - S - - - Domain of unknown function (DUF4956)
KHLDIHDK_00034 0.0 - 3.1.4.52 - T ko:K14051 ko02024,ko02026,map02024,map02026 ko00000,ko00001,ko01000 Putative diguanylate phosphodiesterase
KHLDIHDK_00035 3.68e-161 - - - S ko:K07133 - ko00000 AAA domain
KHLDIHDK_00036 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
KHLDIHDK_00037 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KHLDIHDK_00038 0.0 - - - S - - - Threonine/Serine exporter, ThrE
KHLDIHDK_00039 0.0 - - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KHLDIHDK_00040 3.07e-239 - - - S - - - Protein conserved in bacteria
KHLDIHDK_00041 0.0 - - - S - - - Amidohydrolase family
KHLDIHDK_00042 5.93e-261 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KHLDIHDK_00043 2.08e-58 - - - S - - - Protein of unknown function (DUF3073)
KHLDIHDK_00044 1.54e-145 - - - K - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KHLDIHDK_00045 8.8e-264 - - - T - - - Histidine kinase
KHLDIHDK_00046 1.45e-287 - - - EGP - - - Major Facilitator Superfamily
KHLDIHDK_00047 1.75e-93 - - - I - - - Sterol carrier protein
KHLDIHDK_00048 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KHLDIHDK_00049 1.46e-47 - - - - - - - -
KHLDIHDK_00050 1.15e-176 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
KHLDIHDK_00051 2.41e-101 crgA - - D - - - Involved in cell division
KHLDIHDK_00052 1.56e-162 - - - S - - - Bacterial protein of unknown function (DUF881)
KHLDIHDK_00053 5.37e-290 srtB 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
KHLDIHDK_00054 7.81e-155 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 para-aminobenzoate synthase glutamine amidotransferase component II
KHLDIHDK_00055 0.0 pknB 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
KHLDIHDK_00056 5.61e-224 pknA 2.7.11.1 - T ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
KHLDIHDK_00057 0.0 pbpA - - M ko:K05364 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
KHLDIHDK_00058 0.0 rodA - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KHLDIHDK_00059 0.0 pstP 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
KHLDIHDK_00060 8.95e-105 fhaB - - T - - - Inner membrane component of T3SS, cytoplasmic domain
KHLDIHDK_00061 8.7e-166 fhaA - - T - - - Protein of unknown function (DUF2662)
KHLDIHDK_00062 0.0 pepX 3.4.14.5 - E ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Dipeptidyl peptidase IV (DPP IV) N-terminal region
KHLDIHDK_00063 1.86e-271 pldB 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Serine aminopeptidase, S33
KHLDIHDK_00064 2.45e-119 - - - O - - - Hsp20/alpha crystallin family
KHLDIHDK_00065 6.58e-228 - - - EG - - - EamA-like transporter family
KHLDIHDK_00066 2.73e-37 - - - - - - - -
KHLDIHDK_00067 0.0 - - - S - - - Putative esterase
KHLDIHDK_00068 0.0 lysX - - S - - - Uncharacterised conserved protein (DUF2156)
KHLDIHDK_00069 4.46e-257 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHLDIHDK_00070 1.5e-170 - - - S ko:K07005 - ko00000 Pyridoxamine 5'-phosphate oxidase
KHLDIHDK_00071 3.26e-253 - - - S - - - Fic/DOC family
KHLDIHDK_00072 8.07e-210 - - - M - - - Glycosyltransferase like family 2
KHLDIHDK_00073 0.0 - - - KL - - - Domain of unknown function (DUF3427)
KHLDIHDK_00074 9.5e-98 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
KHLDIHDK_00075 3.02e-70 - - - S - - - Putative heavy-metal-binding
KHLDIHDK_00076 3.51e-191 - - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
KHLDIHDK_00078 0.0 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KHLDIHDK_00079 0.0 degP - - O ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Domain present in PSD-95, Dlg, and ZO-1/2.
KHLDIHDK_00080 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
KHLDIHDK_00081 0.0 fprA 1.18.1.2, 1.19.1.1 - C ko:K00528 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase
KHLDIHDK_00082 3e-222 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KHLDIHDK_00084 6.31e-191 - - - EG - - - EamA-like transporter family
KHLDIHDK_00085 6.59e-254 fbaA 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
KHLDIHDK_00086 2.77e-308 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KHLDIHDK_00087 0.0 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
KHLDIHDK_00088 6.62e-210 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHLDIHDK_00089 5.18e-81 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHLDIHDK_00090 6.9e-257 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHLDIHDK_00092 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Domain of unknown function (DUF1964)
KHLDIHDK_00093 0.0 scrT - - G - - - Transporter major facilitator family protein
KHLDIHDK_00094 1.03e-243 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHLDIHDK_00095 0.0 - - - EGP - - - Sugar (and other) transporter
KHLDIHDK_00096 7.18e-260 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KHLDIHDK_00097 1.02e-259 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KHLDIHDK_00098 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
KHLDIHDK_00099 3.72e-238 - - - K - - - Psort location Cytoplasmic, score
KHLDIHDK_00100 0.0 - - - M - - - cell wall anchor domain protein
KHLDIHDK_00101 0.0 - - - M - - - domain protein
KHLDIHDK_00102 7.92e-221 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
KHLDIHDK_00103 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
KHLDIHDK_00104 0.0 malL 2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16 GH13,GH31 G ko:K01187,ko:K05341,ko:K05343 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
KHLDIHDK_00105 8.41e-300 malE - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_00106 0.0 malC - - G ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00107 1.92e-210 malG - - G ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00108 8.04e-188 traX - - S - - - TraX protein
KHLDIHDK_00109 1.37e-248 - - - K - - - Psort location Cytoplasmic, score
KHLDIHDK_00110 0.0 - 3.2.1.1, 3.2.1.41 CBM48,GH13 M ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 Aamy_C
KHLDIHDK_00111 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KHLDIHDK_00112 5.28e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHLDIHDK_00113 2.45e-224 dnaJ - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 DnaJ molecular chaperone homology domain
KHLDIHDK_00114 5.76e-134 hspR - - K ko:K13640 - ko00000,ko03000 transcriptional regulator, MerR family
KHLDIHDK_00115 5.43e-21 - - - F - - - Psort location CytoplasmicMembrane, score 10.00
KHLDIHDK_00116 3.37e-143 - - - C - - - Acyl-CoA reductase (LuxC)
KHLDIHDK_00117 3.75e-180 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
KHLDIHDK_00118 2.23e-163 - - - S - - - HAD hydrolase, family IA, variant 3
KHLDIHDK_00119 9.04e-172 dedA1 - - S ko:K03975 - ko00000 SNARE associated Golgi protein
KHLDIHDK_00120 3.56e-157 - - - D - - - bacterial-type flagellum organization
KHLDIHDK_00121 1.31e-245 cpaF - - U ko:K02283 - ko00000,ko02035,ko02044 Type II IV secretion system protein
KHLDIHDK_00122 7.27e-95 - - - U ko:K12510 - ko00000,ko02044 Type ii secretion system
KHLDIHDK_00123 6.89e-151 - - - NU - - - Type II secretion system (T2SS), protein F
KHLDIHDK_00124 3.68e-55 - - - S - - - Protein of unknown function (DUF4244)
KHLDIHDK_00125 2.92e-75 - - - U - - - TadE-like protein
KHLDIHDK_00126 3.01e-70 - - - S - - - TIGRFAM helicase secretion neighborhood TadE-like protein
KHLDIHDK_00127 1.33e-275 - 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Diacylglycerol kinase catalytic domain protein
KHLDIHDK_00128 1.98e-127 - - - K - - - Bacterial regulatory proteins, tetR family
KHLDIHDK_00129 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III subunit gamma tau
KHLDIHDK_00130 9.94e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KHLDIHDK_00131 4.77e-271 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
KHLDIHDK_00132 1.1e-90 - - - V - - - Abi-like protein
KHLDIHDK_00133 1.31e-245 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
KHLDIHDK_00134 6.3e-174 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
KHLDIHDK_00135 2.87e-126 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
KHLDIHDK_00136 7.91e-271 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHLDIHDK_00137 1.64e-143 - - - - - - - -
KHLDIHDK_00138 1.12e-216 - - - L - - - Domain of unknown function (DUF4862)
KHLDIHDK_00139 6.1e-229 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KHLDIHDK_00140 1.2e-162 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KHLDIHDK_00141 1.8e-204 - 3.5.1.106 - I ko:K15357 ko00760,ko01120,map00760,map01120 ko00000,ko00001,ko00002,ko01000 carboxylic ester hydrolase activity
KHLDIHDK_00142 0.0 oppA7 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
KHLDIHDK_00143 2.11e-204 oppB6 - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00144 0.0 oppCD2 - - EP ko:K02031,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
KHLDIHDK_00145 2.91e-189 oppF - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_00146 2.23e-232 nanA 4.1.3.3, 4.3.3.7 - EM ko:K01639,ko:K01714 ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
KHLDIHDK_00147 6.11e-189 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KHLDIHDK_00149 0.0 neu 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
KHLDIHDK_00150 1.68e-309 - - - P ko:K07133 - ko00000 Domain of unknown function (DUF4143)
KHLDIHDK_00151 1.14e-195 - - - K - - - FCD
KHLDIHDK_00152 0.0 - - - S - - - Calcineurin-like phosphoesterase
KHLDIHDK_00153 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KHLDIHDK_00154 0.0 pbp5 - - M - - - Transglycosylase
KHLDIHDK_00155 1.35e-219 - - - I - - - PAP2 superfamily
KHLDIHDK_00156 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHLDIHDK_00157 5.84e-150 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHLDIHDK_00158 1.07e-264 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KHLDIHDK_00159 2.13e-136 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHLDIHDK_00160 1.47e-50 hpr - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
KHLDIHDK_00162 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHLDIHDK_00165 2.16e-137 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
KHLDIHDK_00166 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
KHLDIHDK_00167 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formate-tetrahydrofolate ligase
KHLDIHDK_00168 9.13e-81 - - - S - - - Macrophage migration inhibitory factor (MIF)
KHLDIHDK_00169 2.6e-124 - - - S - - - GtrA-like protein
KHLDIHDK_00170 0.0 - - - EGP - - - Major Facilitator Superfamily
KHLDIHDK_00171 2.51e-158 - - - G - - - Phosphoglycerate mutase family
KHLDIHDK_00172 1.41e-188 - - - - - - - -
KHLDIHDK_00173 1.72e-287 - 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
KHLDIHDK_00174 9.01e-226 - - - S - - - Protein of unknown function (DUF805)
KHLDIHDK_00176 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHLDIHDK_00179 1.02e-80 intA - - L - - - Phage integrase, N-terminal SAM-like domain
KHLDIHDK_00181 0.0 - - - P ko:K07243 - ko00000,ko02000 Iron permease FTR1 family
KHLDIHDK_00182 5.41e-159 - - - P ko:K07230 - ko00000,ko02000 Fe2+ transport protein
KHLDIHDK_00183 1.23e-292 - - - S - - - Predicted membrane protein (DUF2318)
KHLDIHDK_00184 8.58e-290 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KHLDIHDK_00185 2.32e-277 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KHLDIHDK_00186 1.14e-186 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHLDIHDK_00187 1.68e-102 - - - S - - - FMN_bind
KHLDIHDK_00188 1.62e-130 - - - K - - - Psort location Cytoplasmic, score 8.87
KHLDIHDK_00189 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
KHLDIHDK_00190 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
KHLDIHDK_00191 0.0 - - - S - - - Putative ABC-transporter type IV
KHLDIHDK_00192 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KHLDIHDK_00193 3.85e-197 pgl 3.1.1.31 - G ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
KHLDIHDK_00194 1.04e-247 opcA - - G - - - Glucose-6-phosphate dehydrogenase subunit
KHLDIHDK_00195 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHLDIHDK_00196 0.0 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
KHLDIHDK_00198 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
KHLDIHDK_00199 2.29e-253 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 Glycosyltransferase like family 2
KHLDIHDK_00200 1.23e-194 icaR - - K - - - Bacterial regulatory proteins, tetR family
KHLDIHDK_00201 4.83e-233 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KHLDIHDK_00202 1.12e-304 amt - - U ko:K03320 - ko00000,ko02000 Ammonium Transporter Family
KHLDIHDK_00203 1.27e-72 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Nitrogen regulatory protein P-II
KHLDIHDK_00204 0.0 glnD 2.7.7.59 - O ko:K00990 ko02020,map02020 ko00000,ko00001,ko01000 Nucleotidyltransferase domain
KHLDIHDK_00205 5.41e-308 dinF - - V - - - MatE
KHLDIHDK_00206 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KHLDIHDK_00207 0.0 murE - - M - - - Domain of unknown function (DUF1727)
KHLDIHDK_00208 3.29e-183 cobQ2 - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
KHLDIHDK_00209 1.06e-51 - - - S - - - granule-associated protein
KHLDIHDK_00210 0.0 - - - S ko:K03688 - ko00000 ABC1 family
KHLDIHDK_00211 0.0 - 3.2.1.185 GH127 S ko:K09955,ko:K18205 - ko00000,ko01000 Beta-L-arabinofuranosidase, GH127
KHLDIHDK_00212 3.93e-193 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KHLDIHDK_00213 3.31e-238 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHLDIHDK_00214 2.77e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
KHLDIHDK_00215 2.88e-109 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
KHLDIHDK_00216 2.15e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KHLDIHDK_00217 1.72e-94 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
KHLDIHDK_00220 2.96e-197 tnp3503b - - L - - - Transposase and inactivated derivatives
KHLDIHDK_00221 6.05e-53 - - - L - - - Transposase
KHLDIHDK_00222 8.56e-151 - - - - - - - -
KHLDIHDK_00223 2.31e-166 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KHLDIHDK_00224 6.16e-145 - - - K - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KHLDIHDK_00225 8.19e-267 - - - T - - - Histidine kinase
KHLDIHDK_00226 1.07e-264 - - - EGP - - - Major Facilitator Superfamily
KHLDIHDK_00227 3.35e-58 - - - - - - - -
KHLDIHDK_00228 2.37e-79 - - - - - - - -
KHLDIHDK_00229 5.48e-165 - - - L - - - Belongs to the 'phage' integrase family
KHLDIHDK_00230 5.04e-175 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KHLDIHDK_00231 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
KHLDIHDK_00232 9.49e-57 csoR - - S ko:K21600 - ko00000,ko03000 Metal-sensitive transcriptional repressor
KHLDIHDK_00233 2.18e-275 rmuC - - S ko:K09760 - ko00000 RmuC family
KHLDIHDK_00234 4.16e-143 pyrE1 - - F - - - Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHLDIHDK_00235 7.31e-218 trmH 2.1.1.34 - J ko:K00556 - ko00000,ko01000,ko03016 RNA methyltransferase TrmH family
KHLDIHDK_00236 8.02e-223 - - - - - - - -
KHLDIHDK_00237 3.72e-205 - - - K - - - Psort location Cytoplasmic, score
KHLDIHDK_00238 6.22e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHLDIHDK_00239 0.0 gatA 6.3.5.6, 6.3.5.7 - F ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KHLDIHDK_00240 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHLDIHDK_00241 2.37e-248 - - - J - - - Acetyltransferase (GNAT) domain
KHLDIHDK_00242 2.66e-68 - - - S - - - Protein of unknown function (DUF2469)
KHLDIHDK_00243 0.0 - - - H - - - Flavin containing amine oxidoreductase
KHLDIHDK_00244 0.0 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KHLDIHDK_00246 6.12e-47 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 Amino-transferase class IV
KHLDIHDK_00247 5.12e-216 - - - L ko:K07485 - ko00000 Transposase
KHLDIHDK_00248 1.25e-44 - - - K - - - AraC-like ligand binding domain
KHLDIHDK_00249 2.65e-192 araN - - G ko:K10188 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_00250 5.07e-159 - - - P ko:K10189,ko:K10241 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00251 7.65e-146 araQ - - U ko:K02026,ko:K10190,ko:K10242 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00252 1.78e-157 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
KHLDIHDK_00253 7.71e-82 tyrA 5.4.99.5 - E ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
KHLDIHDK_00254 0.0 - - - S - - - domain protein
KHLDIHDK_00255 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KHLDIHDK_00256 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
KHLDIHDK_00257 4.17e-163 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHLDIHDK_00258 5.92e-170 glnR - - KT - - - Transcriptional regulatory protein, C terminal
KHLDIHDK_00259 2.07e-121 - - - - - - - -
KHLDIHDK_00260 1.93e-126 mntP - - P - - - Probably functions as a manganese efflux pump
KHLDIHDK_00261 9.28e-118 ppa 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KHLDIHDK_00262 0.0 glgE 2.4.99.16 GH13 G ko:K16147 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
KHLDIHDK_00263 0.0 - - - K - - - RNA polymerase II activating transcription factor binding
KHLDIHDK_00265 8.61e-264 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KHLDIHDK_00266 1.76e-192 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KHLDIHDK_00267 9.96e-40 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHLDIHDK_00268 8.25e-100 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHLDIHDK_00269 1.83e-194 atpH - - C ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHLDIHDK_00270 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHLDIHDK_00271 3.59e-211 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KHLDIHDK_00272 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KHLDIHDK_00273 2.1e-64 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
KHLDIHDK_00274 3.01e-166 nucS - - L ko:K07503 - ko00000,ko01000 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
KHLDIHDK_00275 2.43e-214 - 5.2.1.8 - M ko:K01802 - ko00000,ko01000 FKBP-type peptidyl-prolyl cis-trans isomerase
KHLDIHDK_00276 1.24e-241 - - - - - - - -
KHLDIHDK_00277 7.72e-231 - - - - - - - -
KHLDIHDK_00278 5.13e-219 ybbN - - O ko:K05838 - ko00000,ko03110 Tetratricopeptide repeat
KHLDIHDK_00279 2.63e-150 - - - S - - - CYTH
KHLDIHDK_00282 3.27e-83 psp1 3.5.99.10 - J ko:K09022 - ko00000,ko01000 Endoribonuclease L-PSP
KHLDIHDK_00283 7.25e-241 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
KHLDIHDK_00284 1.38e-228 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
KHLDIHDK_00285 4.97e-292 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KHLDIHDK_00286 1.24e-277 - - - P ko:K02055 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_00287 4.85e-207 - - - U ko:K02054 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00288 1.18e-198 - - - U ko:K02053 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00289 7.87e-304 - - - E ko:K02052 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KHLDIHDK_00290 1.45e-236 - - - S - - - CAAX protease self-immunity
KHLDIHDK_00291 2.54e-173 - - - M - - - Mechanosensitive ion channel
KHLDIHDK_00292 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
KHLDIHDK_00293 1.21e-15 - - - L - - - Transposase DDE domain
KHLDIHDK_00294 6.67e-171 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
KHLDIHDK_00295 0.0 - - - C ko:K06871 - ko00000 Iron-sulfur cluster-binding domain
KHLDIHDK_00296 3.49e-248 - - - K - - - helix_turn _helix lactose operon repressor
KHLDIHDK_00297 0.0 - - - P - - - Domain of unknown function (DUF4976)
KHLDIHDK_00298 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_00299 1.85e-211 - - - P ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00300 1.14e-227 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00301 3.17e-301 - - - S ko:K07133 - ko00000 AAA domain
KHLDIHDK_00302 3.58e-50 - - - L - - - Transposase, Mutator family
KHLDIHDK_00303 2.01e-136 - - - K - - - Bacterial regulatory proteins, tetR family
KHLDIHDK_00304 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
KHLDIHDK_00305 1.04e-110 ogt 2.1.1.63 - L ko:K00567,ko:K07443 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHLDIHDK_00306 2.21e-104 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KHLDIHDK_00307 2.53e-90 ams 2.4.1.4 GH13 G ko:K05341 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
KHLDIHDK_00310 8.61e-104 - - - - - - - -
KHLDIHDK_00311 0.0 - - - Q - - - von Willebrand factor (vWF) type A domain
KHLDIHDK_00312 0.0 - - - M - - - LPXTG cell wall anchor motif
KHLDIHDK_00314 1.08e-66 - - - - - - - -
KHLDIHDK_00316 2.26e-145 - - - - - - - -
KHLDIHDK_00317 2.04e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KHLDIHDK_00318 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KHLDIHDK_00319 2.09e-154 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHLDIHDK_00320 8.39e-102 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KHLDIHDK_00321 2.11e-117 lemA - - S ko:K03744 - ko00000 LemA family
KHLDIHDK_00322 0.0 - - - S - - - Predicted membrane protein (DUF2207)
KHLDIHDK_00323 8.48e-12 - - - S - - - Predicted membrane protein (DUF2207)
KHLDIHDK_00324 0.0 - - - S - - - Predicted membrane protein (DUF2207)
KHLDIHDK_00325 1.08e-19 - - - - - - - -
KHLDIHDK_00326 1e-216 - - - C - - - Oxidoreductase, aldo keto reductase family protein
KHLDIHDK_00327 6.12e-257 - 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
KHLDIHDK_00328 8.91e-139 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHLDIHDK_00329 3.56e-47 - - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
KHLDIHDK_00330 9.48e-85 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
KHLDIHDK_00331 2.21e-269 - - - S - - - Endonuclease/Exonuclease/phosphatase family
KHLDIHDK_00332 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHLDIHDK_00333 2.72e-208 - - - P - - - Cation efflux family
KHLDIHDK_00334 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KHLDIHDK_00335 6.21e-174 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase C26
KHLDIHDK_00337 8.3e-140 - - - - - - - -
KHLDIHDK_00338 1.15e-130 dam 2.1.1.72 - H ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 D12 class N6 adenine-specific DNA methyltransferase
KHLDIHDK_00339 0.0 yjjK - - S ko:K15738 - ko00000,ko02000 ABC transporter
KHLDIHDK_00340 9.42e-95 vapC - - S ko:K07062 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module. An RNase
KHLDIHDK_00341 1.52e-57 - - - S ko:K21495 - ko00000,ko02048 Plasmid stability protein
KHLDIHDK_00342 1.66e-119 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
KHLDIHDK_00343 0.0 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
KHLDIHDK_00344 6.09e-173 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KHLDIHDK_00345 4.87e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
KHLDIHDK_00346 3.1e-149 - - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
KHLDIHDK_00347 2.33e-152 - - - - - - - -
KHLDIHDK_00348 9.97e-114 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHLDIHDK_00349 2.31e-66 - - - S - - - Protein of unknown function (DUF3039)
KHLDIHDK_00350 2.28e-249 - - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
KHLDIHDK_00351 1.05e-101 - - - K - - - MerR, DNA binding
KHLDIHDK_00352 4.04e-154 - - - - - - - -
KHLDIHDK_00353 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHLDIHDK_00354 3.84e-186 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KHLDIHDK_00355 6.52e-173 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHLDIHDK_00356 1.8e-224 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
KHLDIHDK_00359 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
KHLDIHDK_00360 0.0 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_00361 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00363 3.01e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KHLDIHDK_00364 3.25e-223 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KHLDIHDK_00365 9.13e-203 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHLDIHDK_00366 8.26e-272 - - - K - - - helix_turn _helix lactose operon repressor
KHLDIHDK_00368 0.0 fadD 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
KHLDIHDK_00369 1.28e-48 - - - U ko:K02100 - ko00000,ko02000 Sugar (and other) transporter
KHLDIHDK_00370 7.57e-29 - - - U ko:K02100 - ko00000,ko02000 Sugar (and other) transporter
KHLDIHDK_00372 0.0 - - - V ko:K06147,ko:K06148,ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
KHLDIHDK_00373 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_00374 2.44e-221 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00375 2.47e-226 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
KHLDIHDK_00376 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
KHLDIHDK_00377 6.46e-243 - - - K - - - helix_turn _helix lactose operon repressor
KHLDIHDK_00378 1.58e-110 - - - S - - - Oxidoreductase, aldo keto reductase family protein
KHLDIHDK_00379 5.46e-183 - - - L - - - Protein of unknown function (DUF1524)
KHLDIHDK_00380 6.72e-302 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KHLDIHDK_00381 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
KHLDIHDK_00382 0.0 - - - H - - - Protein of unknown function (DUF4012)
KHLDIHDK_00383 1.25e-292 rfbP - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KHLDIHDK_00384 1.46e-139 etp 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Low molecular weight phosphatase family
KHLDIHDK_00385 7.51e-139 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
KHLDIHDK_00387 1.92e-238 - - - L - - - Transposase and inactivated derivatives IS30 family
KHLDIHDK_00388 1.83e-175 - - - M - - - Psort location Cytoplasmic, score 8.87
KHLDIHDK_00389 2.93e-58 - - - M - - - Glycosyltransferase, group 1 family protein
KHLDIHDK_00391 9.98e-77 - - - C - - - Polysaccharide pyruvyl transferase
KHLDIHDK_00392 3.95e-143 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
KHLDIHDK_00393 2.48e-56 XK27_01805 - - M - - - Glycosyltransferase like family 2
KHLDIHDK_00394 2.34e-218 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
KHLDIHDK_00395 1.44e-67 - - - L - - - Transposase, Mutator family
KHLDIHDK_00396 3.52e-12 - - - - - - - -
KHLDIHDK_00398 1.25e-13 - - - L - - - HTH-like domain
KHLDIHDK_00399 2.78e-27 - - - L - - - PFAM Integrase catalytic
KHLDIHDK_00400 2.75e-108 - - - - - - - -
KHLDIHDK_00401 1.12e-86 - - - - - - - -
KHLDIHDK_00402 4.39e-70 - - - L - - - Transposase, Mutator family
KHLDIHDK_00403 2.92e-110 - - - L - - - Transposase, Mutator family
KHLDIHDK_00405 0.0 - - - L - - - PFAM Integrase catalytic
KHLDIHDK_00406 6.31e-25 - - - S - - - AAA ATPase domain
KHLDIHDK_00407 6.93e-127 - - - K - - - Transposase IS116 IS110 IS902
KHLDIHDK_00408 0.0 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
KHLDIHDK_00409 2.88e-91 - - - - - - - -
KHLDIHDK_00410 2.7e-313 wcoI - - DM - - - Psort location CytoplasmicMembrane, score
KHLDIHDK_00411 1.71e-264 - - - - - - - -
KHLDIHDK_00412 2.97e-220 - - - S ko:K21688 - ko00000 G5
KHLDIHDK_00413 5.55e-79 trxA 1.8.1.9 - O ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Belongs to the thioredoxin family
KHLDIHDK_00414 4.32e-155 - - - F - - - Domain of unknown function (DUF4916)
KHLDIHDK_00415 4.71e-203 - - - I - - - Alpha/beta hydrolase family
KHLDIHDK_00416 3.43e-281 nudC 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
KHLDIHDK_00417 1.26e-91 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
KHLDIHDK_00418 1.41e-284 - - - S - - - Uncharacterized conserved protein (DUF2183)
KHLDIHDK_00419 0.0 ptrB 3.4.21.83 - E ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Peptidase, S9A B C family, catalytic domain protein
KHLDIHDK_00420 5.14e-245 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KHLDIHDK_00421 2.53e-274 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
KHLDIHDK_00422 2.7e-172 crp - - K ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
KHLDIHDK_00423 0.0 pon1 - - M - - - Transglycosylase
KHLDIHDK_00424 3.34e-303 namA - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
KHLDIHDK_00425 1.53e-289 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
KHLDIHDK_00426 3.61e-158 - - - K - - - DeoR C terminal sensor domain
KHLDIHDK_00427 0.0 galT 2.7.7.12 - C ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 Galactose-1-phosphate uridyl transferase, N-terminal domain
KHLDIHDK_00428 3.56e-298 galK 2.7.1.6, 2.7.7.12 - G ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family. GalK subfamily
KHLDIHDK_00429 1.32e-57 - - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
KHLDIHDK_00430 0.0 - - - S ko:K09157 - ko00000 UPF0210 protein
KHLDIHDK_00431 3.37e-148 spoU 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KHLDIHDK_00432 1.03e-237 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 FES
KHLDIHDK_00433 1.35e-131 - - - - - - - -
KHLDIHDK_00434 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHLDIHDK_00435 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHLDIHDK_00436 0.0 - - - E - - - Transglutaminase-like superfamily
KHLDIHDK_00437 5.59e-309 - - - S - - - Protein of unknown function DUF58
KHLDIHDK_00438 0.0 - - - S - - - Fibronectin type 3 domain
KHLDIHDK_00439 5.07e-283 pknK 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
KHLDIHDK_00440 0.0 - - - L - - - PD-(D/E)XK nuclease superfamily
KHLDIHDK_00441 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Belongs to the helicase family. UvrD subfamily
KHLDIHDK_00442 9.52e-301 - - - G - - - Major Facilitator Superfamily
KHLDIHDK_00443 2.38e-172 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KHLDIHDK_00444 2.06e-208 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHLDIHDK_00445 0.0 rnj - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHLDIHDK_00446 0.0 pepN 3.4.11.2 - E ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Peptidase family M1 domain
KHLDIHDK_00447 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHLDIHDK_00448 5.28e-159 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KHLDIHDK_00449 0.0 - - - L - - - Psort location Cytoplasmic, score
KHLDIHDK_00450 2.52e-263 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KHLDIHDK_00451 7.91e-270 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Cell division ATP-binding protein FtsE
KHLDIHDK_00452 1.9e-206 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in cellular division
KHLDIHDK_00453 2.5e-210 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain protein
KHLDIHDK_00454 3.26e-106 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KHLDIHDK_00455 6.96e-198 glnH - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter, substrate-binding protein, family 3
KHLDIHDK_00456 4.57e-217 glnH - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter, substrate-binding protein, family 3
KHLDIHDK_00457 1.54e-222 yecS - - E ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00458 3.69e-193 tcyC 3.6.3.21 - E ko:K02028,ko:K02029 - ko00000,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_00459 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KHLDIHDK_00460 1.77e-180 - 5.4.99.28, 5.4.99.29 - J ko:K06177 - ko00000,ko01000,ko03009,ko03016 RNA pseudouridylate synthase
KHLDIHDK_00461 3.73e-239 - - - K - - - Periplasmic binding protein domain
KHLDIHDK_00462 3.1e-217 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00463 2.47e-226 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
KHLDIHDK_00464 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
KHLDIHDK_00465 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_00466 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_00467 3.16e-184 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KHLDIHDK_00468 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
KHLDIHDK_00469 7.8e-215 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00470 3.46e-192 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00471 2.77e-177 - - - EP ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 oligopeptide transport protein of the ABC superfamily, ATP-binding component
KHLDIHDK_00472 3.37e-177 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_00473 1.42e-245 cbs 2.5.1.47, 4.2.1.22 - E ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
KHLDIHDK_00474 7.19e-280 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
KHLDIHDK_00475 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
KHLDIHDK_00476 1.95e-119 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KHLDIHDK_00477 7.45e-134 cysE - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KHLDIHDK_00478 0.0 aap1 - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
KHLDIHDK_00479 0.0 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHLDIHDK_00480 2.91e-310 dgt 3.1.5.1 - F ko:K01129 ko00230,map00230 ko00000,ko00001,ko01000 Phosphohydrolase-associated domain
KHLDIHDK_00481 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KHLDIHDK_00482 5.04e-90 - - - S - - - PIN domain
KHLDIHDK_00483 1.92e-46 - - - - - - - -
KHLDIHDK_00484 2.31e-199 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KHLDIHDK_00485 1.2e-148 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KHLDIHDK_00486 0.0 - - - EK ko:K03710,ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000,ko03000 Alanine-glyoxylate amino-transferase
KHLDIHDK_00487 1.36e-267 - - - P - - - Citrate transporter
KHLDIHDK_00488 9.8e-41 - - - - - - - -
KHLDIHDK_00489 1.34e-50 - - - G - - - Alpha-L-arabinofuranosidase C-terminal domain
KHLDIHDK_00490 2.25e-205 - - - K - - - Helix-turn-helix domain, rpiR family
KHLDIHDK_00493 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_00494 9.75e-295 - - - K - - - helix_turn _helix lactose operon repressor
KHLDIHDK_00495 0.0 - 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
KHLDIHDK_00496 1.98e-18 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
KHLDIHDK_00497 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
KHLDIHDK_00498 2.56e-110 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 peptide-methionine (S)-S-oxide reductase activity
KHLDIHDK_00499 7.65e-183 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_00500 3.69e-248 - - - M - - - Conserved repeat domain
KHLDIHDK_00501 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
KHLDIHDK_00502 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHLDIHDK_00503 3.27e-230 yogA - - C - - - Zinc-binding dehydrogenase
KHLDIHDK_00504 4.18e-111 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KHLDIHDK_00505 4.92e-286 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KHLDIHDK_00506 7.7e-95 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
KHLDIHDK_00507 4.41e-98 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KHLDIHDK_00508 4.47e-33 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KHLDIHDK_00509 4.25e-91 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KHLDIHDK_00510 9.84e-85 - - - - - - - -
KHLDIHDK_00511 2.35e-112 fur - - P ko:K03711 - ko00000,ko03000 Ferric uptake regulator family
KHLDIHDK_00512 1.14e-179 - - - S - - - TIGRFAM TIGR03943 family protein
KHLDIHDK_00513 7.68e-254 - - - S ko:K07089 - ko00000 Predicted permease
KHLDIHDK_00514 3.79e-05 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 50S ribosomal protein L31
KHLDIHDK_00515 2.82e-208 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
KHLDIHDK_00516 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
KHLDIHDK_00517 0.0 aldH 1.2.1.3, 1.2.99.10 - C ko:K00128,ko:K22445 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldehyde dehydrogenase family
KHLDIHDK_00518 1.04e-309 purD 6.3.3.1, 6.3.4.13 - F ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
KHLDIHDK_00519 6.44e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KHLDIHDK_00520 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KHLDIHDK_00521 0.0 - - - L ko:K03502 - ko00000,ko03400 DNA-damage repair protein (DNA polymerase IV) K00961
KHLDIHDK_00522 5.49e-42 - - - - - - - -
KHLDIHDK_00523 2.77e-17 - - - C - - - Aldo/keto reductase family
KHLDIHDK_00524 2.67e-132 nnrE - - L - - - Uracil DNA glycosylase superfamily
KHLDIHDK_00528 6.15e-40 - - - S - - - Protein of unknown function (DUF4230)
KHLDIHDK_00529 8.33e-187 - - - - - - - -
KHLDIHDK_00530 3.12e-143 - - - Q - - - D-alanine [D-alanyl carrier protein] ligase activity
KHLDIHDK_00531 0.0 - - - Q - - - D-alanine [D-alanyl carrier protein] ligase activity
KHLDIHDK_00532 2.51e-297 - - - I - - - alpha/beta hydrolase fold
KHLDIHDK_00533 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 CobB/CobQ-like glutamine amidotransferase domain
KHLDIHDK_00534 4.83e-176 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KHLDIHDK_00535 3.02e-294 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KHLDIHDK_00536 9.36e-294 - 2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83 - E ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
KHLDIHDK_00537 9.06e-279 - - - M - - - Glycosyl transferase 4-like domain
KHLDIHDK_00538 5.2e-253 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Beta-eliminating lyase
KHLDIHDK_00540 3.25e-142 - - - S ko:K03453 - ko00000 SBF-like CPA transporter family (DUF4137)
KHLDIHDK_00541 5.77e-81 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KHLDIHDK_00542 1.9e-104 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KHLDIHDK_00543 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHLDIHDK_00544 4.1e-293 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHLDIHDK_00545 1.7e-103 tmp1 - - S - - - Domain of unknown function (DUF4391)
KHLDIHDK_00546 2.88e-45 tmp1 - - S - - - Domain of unknown function (DUF4391)
KHLDIHDK_00547 9e-187 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
KHLDIHDK_00548 1.24e-237 - - - S - - - Conserved hypothetical protein 698
KHLDIHDK_00549 3.89e-28 - - - S - - - Psort location CytoplasmicMembrane, score
KHLDIHDK_00550 2.83e-39 - - - S ko:K07015 - ko00000 polysaccharide biosynthetic process
KHLDIHDK_00551 1.43e-80 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHLDIHDK_00552 2.37e-111 - - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHLDIHDK_00553 6.38e-87 - - - K - - - MerR family regulatory protein
KHLDIHDK_00554 4.61e-250 adh 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
KHLDIHDK_00555 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
KHLDIHDK_00556 4.18e-141 - - - P ko:K07220 - ko00000 Protein of unknown function DUF47
KHLDIHDK_00557 2.56e-216 - - - C - - - Domain of unknown function
KHLDIHDK_00558 8.55e-305 - - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_00559 5.39e-182 - - - G ko:K02026,ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00560 1.92e-218 - - - P ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00561 4.8e-203 - - - P - - - Phosphate transporter family
KHLDIHDK_00562 1.12e-243 - - - K - - - helix_turn _helix lactose operon repressor
KHLDIHDK_00563 1.28e-181 - - - K - - - LysR substrate binding domain
KHLDIHDK_00564 5.6e-130 - - - K - - - LysR substrate binding domain
KHLDIHDK_00565 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KHLDIHDK_00566 2.2e-308 - - - V - - - MatE
KHLDIHDK_00567 1.27e-158 - - - L ko:K07457 - ko00000 endonuclease III
KHLDIHDK_00568 1e-148 - 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
KHLDIHDK_00569 1.18e-53 - 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
KHLDIHDK_00570 2.92e-237 - - - S ko:K07088 - ko00000 Membrane transport protein
KHLDIHDK_00571 6.98e-165 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
KHLDIHDK_00572 2.04e-95 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin domain
KHLDIHDK_00573 7.18e-200 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
KHLDIHDK_00574 3.9e-170 tam 2.1.1.144 - S ko:K00598 - ko00000,ko01000 Methyltransferase domain
KHLDIHDK_00575 1.23e-61 - - - L - - - Transposase
KHLDIHDK_00576 5.19e-22 - - - - - - - -
KHLDIHDK_00577 9.08e-68 - - - - - - - -
KHLDIHDK_00578 4.83e-107 - - - M - - - L,D-transpeptidase catalytic domain
KHLDIHDK_00579 3.58e-168 - - - V ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
KHLDIHDK_00580 5e-162 - - - V ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_00581 6.57e-136 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHLDIHDK_00582 7.18e-121 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHLDIHDK_00583 1.78e-307 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
KHLDIHDK_00584 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase large chain, oligomerisation domain
KHLDIHDK_00585 2.65e-217 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KHLDIHDK_00586 9.2e-136 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KHLDIHDK_00587 2.93e-174 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Exonuclease, DNA polymerase III, epsilon subunit family
KHLDIHDK_00588 6.79e-07 - - - - - - - -
KHLDIHDK_00589 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
KHLDIHDK_00590 7.91e-162 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
KHLDIHDK_00591 7.76e-299 metC1 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
KHLDIHDK_00592 1.32e-56 - - - O - - - Glutaredoxin
KHLDIHDK_00593 2.13e-222 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
KHLDIHDK_00594 1.41e-11 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
KHLDIHDK_00595 1.79e-170 hflK - - O - - - prohibitin homologues
KHLDIHDK_00596 9.81e-72 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
KHLDIHDK_00597 1.92e-202 - - - S - - - Patatin-like phospholipase
KHLDIHDK_00598 4.68e-190 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KHLDIHDK_00599 3.24e-219 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
KHLDIHDK_00600 5.62e-165 - - - S - - - Vitamin K epoxide reductase
KHLDIHDK_00601 8.9e-216 PPA1328 3.1.3.97, 3.1.4.57 - S ko:K07053,ko:K20859 ko00440,map00440 ko00000,ko00001,ko01000 DNA polymerase alpha chain like domain
KHLDIHDK_00602 2.77e-45 - - - S - - - Protein of unknown function (DUF3107)
KHLDIHDK_00603 0.0 mphA - - S - - - Aminoglycoside phosphotransferase
KHLDIHDK_00604 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KHLDIHDK_00605 0.0 - - - S - - - Zincin-like metallopeptidase
KHLDIHDK_00606 2.12e-210 sdrC - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KHLDIHDK_00607 2.42e-96 - - - S - - - Protein of unknown function (DUF3052)
KHLDIHDK_00609 1.65e-299 - - - NU - - - Tfp pilus assembly protein FimV
KHLDIHDK_00610 8.77e-282 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KHLDIHDK_00611 6.58e-294 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KHLDIHDK_00612 0.0 - - - I - - - acetylesterase activity
KHLDIHDK_00613 6.84e-166 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
KHLDIHDK_00614 1.58e-197 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 - H ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHLDIHDK_00615 5.79e-172 - - - P - - - Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00616 2.17e-243 - - - P - - - NMT1/THI5 like
KHLDIHDK_00617 7.02e-287 - - - E - - - Aminotransferase class I and II
KHLDIHDK_00618 5.62e-182 - - - P ko:K16784 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_00619 2.25e-08 - 2.8.2.22 - S ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
KHLDIHDK_00620 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KHLDIHDK_00621 0.0 - - - S - - - Tetratricopeptide repeat
KHLDIHDK_00622 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHLDIHDK_00623 1.35e-262 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KHLDIHDK_00624 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KHLDIHDK_00625 4.13e-182 - - - S - - - Domain of unknown function (DUF4191)
KHLDIHDK_00626 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHLDIHDK_00627 4.43e-130 - - - S - - - Protein of unknown function (DUF3043)
KHLDIHDK_00628 0.0 argE - - E - - - Peptidase dimerisation domain
KHLDIHDK_00629 3.75e-141 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
KHLDIHDK_00630 0.0 ykoD - - P ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_00631 1.24e-209 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KHLDIHDK_00632 1.99e-205 tsnR - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHLDIHDK_00633 4.35e-258 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHLDIHDK_00634 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Phenylalanyl-tRNA synthetase beta
KHLDIHDK_00635 2.96e-120 - - - - - - - -
KHLDIHDK_00636 1.15e-259 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KHLDIHDK_00637 9.67e-272 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KHLDIHDK_00638 2.39e-226 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
KHLDIHDK_00639 9.64e-317 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
KHLDIHDK_00640 7.19e-234 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KHLDIHDK_00641 1.24e-109 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KHLDIHDK_00642 1.2e-303 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
KHLDIHDK_00643 1.38e-76 - - - L - - - PFAM Integrase catalytic
KHLDIHDK_00645 1.72e-58 - - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
KHLDIHDK_00646 1.62e-44 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
KHLDIHDK_00647 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
KHLDIHDK_00648 3.55e-39 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 ThiS family
KHLDIHDK_00649 1.02e-201 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KHLDIHDK_00650 3.41e-190 thiF 2.7.7.73, 2.7.7.80, 2.8.1.11 - H ko:K03148,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
KHLDIHDK_00651 6.08e-93 - - - P - - - Rhodanese Homology Domain
KHLDIHDK_00652 6.92e-133 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KHLDIHDK_00653 9.01e-179 - - - S - - - Putative ABC-transporter type IV
KHLDIHDK_00654 2.29e-98 - - - S - - - Protein of unknown function (DUF975)
KHLDIHDK_00655 0.0 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KHLDIHDK_00656 7.66e-308 - - - L - - - Tetratricopeptide repeat
KHLDIHDK_00657 7.39e-254 - - - G - - - Haloacid dehalogenase-like hydrolase
KHLDIHDK_00659 7.1e-177 tlyA 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
KHLDIHDK_00660 1.49e-148 - - - - - - - -
KHLDIHDK_00661 1.25e-64 trkA - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
KHLDIHDK_00662 4.29e-50 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
KHLDIHDK_00663 1.11e-235 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHLDIHDK_00664 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KHLDIHDK_00665 5.47e-151 - - - S - - - Haloacid dehalogenase-like hydrolase
KHLDIHDK_00666 1.27e-71 - - - J - - - Acetyltransferase (GNAT) domain
KHLDIHDK_00667 3.46e-78 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
KHLDIHDK_00668 6.07e-223 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_00669 9.6e-156 - - - S - - - ABC-2 family transporter protein
KHLDIHDK_00670 4.04e-125 - - - S - - - ABC-2 family transporter protein
KHLDIHDK_00671 8.48e-09 - - - S - - - Transposon-encoded protein TnpV
KHLDIHDK_00672 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase N terminus
KHLDIHDK_00673 1.15e-300 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KHLDIHDK_00674 1.26e-124 - - - - - - - -
KHLDIHDK_00675 4.5e-177 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHLDIHDK_00676 5.15e-116 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
KHLDIHDK_00677 1.29e-25 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
KHLDIHDK_00678 0.0 - - - S ko:K09118 - ko00000 Uncharacterised protein family (UPF0182)
KHLDIHDK_00679 6.7e-121 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
KHLDIHDK_00680 4.23e-147 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KHLDIHDK_00681 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHLDIHDK_00682 9.02e-228 - - - C - - - Aldo/keto reductase family
KHLDIHDK_00683 2.49e-313 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KHLDIHDK_00684 1.09e-112 - - - D - - - Septum formation initiator
KHLDIHDK_00685 1.13e-132 - - - S ko:K09009 - ko00000 Protein of unknown function (DUF501)
KHLDIHDK_00686 6.12e-232 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
KHLDIHDK_00688 3.47e-123 - - - - - - - -
KHLDIHDK_00689 0.0 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase alpha chain
KHLDIHDK_00690 8.17e-98 fkbP 5.2.1.8 - G ko:K01802 - ko00000,ko01000 Peptidyl-prolyl cis-trans
KHLDIHDK_00691 2.89e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KHLDIHDK_00692 5.18e-203 hlyIII - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
KHLDIHDK_00693 0.0 pdtaS 2.7.13.3 - T ko:K00936 - ko00000,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
KHLDIHDK_00694 8.13e-62 whiB - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KHLDIHDK_00695 0.0 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
KHLDIHDK_00696 6.52e-306 lytR2 - - K - - - Cell envelope-related transcriptional attenuator domain
KHLDIHDK_00697 2.06e-74 whiB2 - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KHLDIHDK_00698 0.0 - - - S - - - Glycosyl transferase, family 2
KHLDIHDK_00699 0.0 - - - - - - - -
KHLDIHDK_00700 2.13e-101 - - - S - - - Zincin-like metallopeptidase
KHLDIHDK_00701 1.97e-188 - - - T - - - Eukaryotic phosphomannomutase
KHLDIHDK_00702 3.05e-157 pyrE_1 - - S - - - Phosphoribosyl transferase domain
KHLDIHDK_00703 2.36e-248 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
KHLDIHDK_00704 2.03e-163 cseB - - T - - - Response regulator receiver domain protein
KHLDIHDK_00705 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KHLDIHDK_00706 2.16e-130 carD - - K ko:K07736 - ko00000,ko03000 CarD-like/TRCF domain
KHLDIHDK_00707 2.52e-114 ispF 2.7.7.60, 4.6.1.12 - H ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KHLDIHDK_00708 6.37e-174 znuB - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
KHLDIHDK_00709 1.29e-206 - - - P ko:K02074 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_00710 2.51e-262 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
KHLDIHDK_00711 2.64e-210 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHLDIHDK_00712 0.0 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
KHLDIHDK_00713 2.16e-148 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KHLDIHDK_00714 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KHLDIHDK_00715 3.81e-228 terC - - P ko:K05794 - ko00000 Integral membrane protein, TerC family
KHLDIHDK_00716 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase
KHLDIHDK_00717 1.12e-142 aspA 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
KHLDIHDK_00719 1.77e-168 pdtaR - - T ko:K22010 - ko00000,ko00002,ko02022 Response regulator receiver domain protein
KHLDIHDK_00720 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHLDIHDK_00721 4.64e-227 - - - L - - - NIF3 (NGG1p interacting factor 3)
KHLDIHDK_00722 4e-162 - - - L - - - NUDIX domain
KHLDIHDK_00723 0.0 glgX 3.2.1.68 CBM48,GH13 G ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
KHLDIHDK_00724 5.39e-35 zntR - - K - - - bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
KHLDIHDK_00725 1.23e-116 - - - K - - - Putative zinc ribbon domain
KHLDIHDK_00726 1.78e-161 - - - S - - - GyrI-like small molecule binding domain
KHLDIHDK_00727 4.52e-28 - 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
KHLDIHDK_00729 6.39e-157 - - - - - - - -
KHLDIHDK_00730 1.88e-273 - - - - - - - -
KHLDIHDK_00731 0.0 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KHLDIHDK_00732 8.03e-296 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHLDIHDK_00733 0.0 pta 2.3.1.8 - C ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphate acetyltransferase
KHLDIHDK_00735 1.95e-244 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHLDIHDK_00736 0.0 yrhL - - I - - - Psort location CytoplasmicMembrane, score 9.99
KHLDIHDK_00740 0.0 - - - V - - - T5orf172
KHLDIHDK_00741 9.94e-24 - - - - - - - -
KHLDIHDK_00742 2.77e-51 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
KHLDIHDK_00743 5.73e-47 - - - L ko:K07483 - ko00000 Integrase core domain
KHLDIHDK_00744 2.27e-101 istB - - L - - - IstB-like ATP binding protein
KHLDIHDK_00745 0.0 - - - L - - - PFAM Integrase catalytic
KHLDIHDK_00746 8.46e-126 - - - - - - - -
KHLDIHDK_00747 2.98e-127 - - - - - - - -
KHLDIHDK_00748 1.67e-123 - - - - - - - -
KHLDIHDK_00749 4.36e-104 - - - U - - - Relaxase/Mobilisation nuclease domain
KHLDIHDK_00750 4.17e-83 - - - K - - - Helix-turn-helix XRE-family like proteins
KHLDIHDK_00751 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KHLDIHDK_00752 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
KHLDIHDK_00753 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHLDIHDK_00754 1.56e-85 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KHLDIHDK_00755 7.2e-174 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
KHLDIHDK_00758 3.03e-196 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KHLDIHDK_00759 7.36e-225 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
KHLDIHDK_00760 6.93e-281 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHLDIHDK_00761 5.54e-146 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00762 2.4e-286 - - - S - - - Peptidase dimerisation domain
KHLDIHDK_00763 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KHLDIHDK_00764 1.5e-52 - - - - - - - -
KHLDIHDK_00765 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
KHLDIHDK_00766 5.19e-222 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KHLDIHDK_00767 1.35e-153 - - - S - - - Protein of unknown function (DUF3000)
KHLDIHDK_00768 0.0 rnd 3.1.13.5 - J ko:K03684 - ko00000,ko01000,ko03016 3'-5' exonuclease
KHLDIHDK_00769 3.47e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KHLDIHDK_00770 1.24e-312 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
KHLDIHDK_00771 1.3e-78 - - - - - - - -
KHLDIHDK_00772 2.96e-151 clpP1 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KHLDIHDK_00773 1.28e-155 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KHLDIHDK_00774 0.0 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KHLDIHDK_00777 5.51e-308 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
KHLDIHDK_00778 6.11e-311 nhaA - - P ko:K03313 - ko00000,ko02000 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KHLDIHDK_00779 2.76e-216 fmt2 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
KHLDIHDK_00780 3.95e-147 safC - - S - - - O-methyltransferase
KHLDIHDK_00781 3.43e-234 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
KHLDIHDK_00782 0.0 sdhA 1.3.5.1, 1.3.5.4, 1.4.3.16 - C ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 Succinate dehydrogenase flavoprotein subunit
KHLDIHDK_00783 0.0 dprA - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
KHLDIHDK_00784 0.0 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI C-terminal
KHLDIHDK_00785 4.34e-99 yraN - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
KHLDIHDK_00786 3.1e-29 - - - L - - - Transposase and inactivated derivatives IS30 family
KHLDIHDK_00787 2.26e-210 pdxY 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
KHLDIHDK_00788 0.0 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Aminotransferase class-V
KHLDIHDK_00789 1.58e-210 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHLDIHDK_00790 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
KHLDIHDK_00791 1.37e-178 - - - K - - - helix_turn_helix, Lux Regulon
KHLDIHDK_00792 0.0 - - - T - - - Histidine kinase
KHLDIHDK_00793 0.0 pip 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 alpha/beta hydrolase fold
KHLDIHDK_00794 2.3e-190 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHLDIHDK_00795 5.68e-198 glnH - - ET ko:K02030,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KHLDIHDK_00796 2.23e-176 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ATP binding protein of ABC transporter for glutamate aspartate K02028
KHLDIHDK_00797 2.26e-153 glnP - - E ko:K02029,ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00798 4.1e-144 glnP2 - - E ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_00799 1.7e-258 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KHLDIHDK_00800 1.36e-209 tetD - - K ko:K13653 - ko00000,ko03000 Arac family
KHLDIHDK_00801 4.15e-39 - - - S ko:K02890,ko:K07343 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 rRNA binding
KHLDIHDK_00803 4.68e-314 - - - V - - - MatE
KHLDIHDK_00804 0.0 - - - L - - - ABC transporter
KHLDIHDK_00806 6.41e-299 - - - K - - - Fic/DOC family
KHLDIHDK_00807 7.81e-79 yccF - - S - - - Inner membrane component domain
KHLDIHDK_00808 6.44e-205 - - - J - - - Methyltransferase domain
KHLDIHDK_00809 1.67e-110 - - - S - - - Cupin 2, conserved barrel domain protein
KHLDIHDK_00810 5.72e-69 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
KHLDIHDK_00811 5.09e-51 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
KHLDIHDK_00812 9.28e-311 - - - S - - - HipA-like C-terminal domain
KHLDIHDK_00813 2.42e-24 higA - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix
KHLDIHDK_00814 2.4e-279 - - - G - - - Transmembrane secretion effector
KHLDIHDK_00815 8.2e-152 - - - K - - - Bacterial regulatory proteins, tetR family
KHLDIHDK_00816 7.74e-17 - - - - - - - -
KHLDIHDK_00817 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
KHLDIHDK_00818 1.45e-17 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
KHLDIHDK_00819 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KHLDIHDK_00820 1.53e-307 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
KHLDIHDK_00821 6.11e-189 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KHLDIHDK_00822 2.11e-223 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KHLDIHDK_00823 5.28e-282 - - - GK - - - ROK family
KHLDIHDK_00824 5.97e-205 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
KHLDIHDK_00825 0.0 gtr - - U ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Sugar (and other) transporter
KHLDIHDK_00826 0.0 - - - P - - - Domain of unknown function (DUF4976)
KHLDIHDK_00827 0.0 - - - C ko:K06871 - ko00000 Iron-sulfur cluster-binding domain
KHLDIHDK_00828 2.15e-155 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
KHLDIHDK_00829 1.51e-75 - - - L - - - Helix-turn-helix domain
KHLDIHDK_00830 5.33e-119 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
KHLDIHDK_00831 2.38e-83 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KHLDIHDK_00833 1.56e-310 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
KHLDIHDK_00834 6.52e-139 - - - E - - - haloacid dehalogenase-like hydrolase
KHLDIHDK_00835 7.29e-209 - - - G - - - Phosphoglycerate mutase family
KHLDIHDK_00836 8.43e-299 rutG - - F ko:K02824,ko:K03458 - ko00000,ko02000 Permease family
KHLDIHDK_00837 0.0 - - - JKL - - - helicase superfamily c-terminal domain
KHLDIHDK_00838 0.0 nplT 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
KHLDIHDK_00839 2.33e-240 pitB - - P ko:K03306 - ko00000 Phosphate transporter family
KHLDIHDK_00840 2.24e-146 - - - P ko:K07220 - ko00000 Protein of unknown function DUF47
KHLDIHDK_00841 2.11e-140 - - - K - - - helix_turn_helix, Lux Regulon
KHLDIHDK_00842 1.16e-285 - - - T - - - Histidine kinase
KHLDIHDK_00843 2.12e-14 - 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
KHLDIHDK_00844 4.35e-238 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_00845 9.55e-285 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KHLDIHDK_00846 0.0 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KHLDIHDK_00847 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
KHLDIHDK_00848 6.13e-52 - - - E - - - GDSL-like Lipase/Acylhydrolase family
KHLDIHDK_00849 5.85e-260 - - - - - - - -
KHLDIHDK_00850 2.32e-141 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Peptidase family S51
KHLDIHDK_00851 2.15e-138 pncA 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Isochorismatase family
KHLDIHDK_00852 1.95e-221 - - - M - - - pfam nlp p60
KHLDIHDK_00853 1.78e-203 - - - I - - - Serine aminopeptidase, S33
KHLDIHDK_00854 1.11e-54 - - - S - - - Protein of unknown function (DUF2975)
KHLDIHDK_00855 6.32e-42 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
KHLDIHDK_00856 4.45e-309 pbuX - - F ko:K03458 - ko00000 Permease family
KHLDIHDK_00857 3.1e-137 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KHLDIHDK_00858 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KHLDIHDK_00859 2.78e-85 - - - S - - - Domain of unknown function (DUF4418)
KHLDIHDK_00860 1.89e-276 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KHLDIHDK_00861 3.43e-207 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KHLDIHDK_00862 5.26e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHLDIHDK_00863 1.47e-200 - - - S ko:K07010 - ko00000,ko01002 Peptidase C26
KHLDIHDK_00864 5.2e-118 - 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 cytidine deaminase activity
KHLDIHDK_00865 7.72e-70 - - - S - - - SdpI/YhfL protein family
KHLDIHDK_00866 1.03e-143 - - - E - - - Transglutaminase-like superfamily
KHLDIHDK_00867 3.14e-87 - - - T - - - PemK-like, MazF-like toxin of type II toxin-antitoxin system
KHLDIHDK_00868 2.55e-65 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
KHLDIHDK_00869 8.14e-165 - 5.4.2.12 - G ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
KHLDIHDK_00870 5.96e-77 - - - S - - - Bacterial protein of unknown function (DUF948)
KHLDIHDK_00871 6.59e-48 - - - - - - - -
KHLDIHDK_00872 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHLDIHDK_00873 2.12e-99 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KHLDIHDK_00874 3.1e-254 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KHLDIHDK_00875 1.01e-90 - 3.4.23.43 - S ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type IV leader peptidase family
KHLDIHDK_00876 4.31e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KHLDIHDK_00877 0.0 aroB 2.7.1.71, 4.2.3.4 - H ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KHLDIHDK_00878 2.45e-103 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
KHLDIHDK_00879 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KHLDIHDK_00880 0.0 - - - S - - - L,D-transpeptidase catalytic domain
KHLDIHDK_00881 0.0 sufB - - O ko:K09014 - ko00000 FeS assembly protein SufB
KHLDIHDK_00882 4.34e-301 sufD - - O ko:K09015 - ko00000 FeS assembly protein SufD
KHLDIHDK_00883 2.81e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
KHLDIHDK_00884 6.21e-303 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KHLDIHDK_00885 8.33e-133 iscU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
KHLDIHDK_00886 2.19e-142 - - - S - - - Iron-sulfur cluster assembly protein
KHLDIHDK_00887 1.6e-309 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KHLDIHDK_00888 7.89e-212 spoU2 - - J - - - SpoU rRNA Methylase family
KHLDIHDK_00890 4.41e-175 - 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KHLDIHDK_00891 2.76e-76 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
KHLDIHDK_00892 9.79e-278 phoH - - T ko:K06217 - ko00000 PhoH-like protein
KHLDIHDK_00893 1.33e-133 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KHLDIHDK_00894 0.0 corC - - S - - - CBS domain
KHLDIHDK_00895 3.86e-236 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHLDIHDK_00896 0.0 fadD2 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
KHLDIHDK_00897 6.65e-261 pntA 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 NAD(P) transhydrogenase subunit alpha part 1 K00324
KHLDIHDK_00898 3.55e-58 pntAB 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 4TM region of pyridine nucleotide transhydrogenase, mitoch
KHLDIHDK_00899 2.11e-308 pntB 1.6.1.2 - C ko:K00325 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KHLDIHDK_00900 3.57e-299 - - - EGP ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
KHLDIHDK_00901 2.59e-137 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KHLDIHDK_00902 2.72e-288 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Amino-transferase class IV
KHLDIHDK_00903 6.23e-189 mazG 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 Psort location Cytoplasmic, score 8.87
KHLDIHDK_00904 4.82e-179 - - - S - - - UPF0126 domain
KHLDIHDK_00905 4.75e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
KHLDIHDK_00906 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KHLDIHDK_00907 0.0 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
KHLDIHDK_00909 1.59e-243 - - - K - - - helix_turn _helix lactose operon repressor
KHLDIHDK_00910 1.67e-77 - - - K - - - helix_turn _helix lactose operon repressor
KHLDIHDK_00911 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase NADPH large subunit
KHLDIHDK_00912 0.0 gltD 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
KHLDIHDK_00913 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
KHLDIHDK_00914 0.0 - - - S - - - Glycosyl hydrolases related to GH101 family, GH129
KHLDIHDK_00915 4.87e-106 - - - - - - - -
KHLDIHDK_00916 5.58e-311 glgA 2.4.1.342 GT4 G ko:K16148 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000,ko01003 Starch synthase catalytic domain
KHLDIHDK_00917 1.7e-201 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_00918 6.7e-203 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KHLDIHDK_00919 4.92e-118 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Redoxin
KHLDIHDK_00920 4.06e-180 - - - - - - - -
KHLDIHDK_00921 8.89e-53 - - - L - - - Transposase, Mutator family
KHLDIHDK_00922 2.39e-227 - - - I - - - alpha/beta hydrolase fold
KHLDIHDK_00923 1.93e-117 lppD - - S - - - Appr-1'-p processing enzyme
KHLDIHDK_00924 6.95e-188 - - - S - - - phosphoesterase or phosphohydrolase
KHLDIHDK_00925 4.16e-181 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KHLDIHDK_00927 4.32e-172 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
KHLDIHDK_00928 6.37e-257 trmI 2.1.1.219, 2.1.1.220 - J ko:K07442 - ko00000,ko01000,ko03016 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KHLDIHDK_00929 1.18e-128 sixA - - T ko:K08296 - ko00000,ko01000 Phosphoglycerate mutase family
KHLDIHDK_00931 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KHLDIHDK_00932 5.54e-208 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
KHLDIHDK_00933 8.46e-240 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KHLDIHDK_00934 0.0 glnE 2.7.7.42, 2.7.7.89 - H ko:K00982 - ko00000,ko01000 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
KHLDIHDK_00935 8.93e-229 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KHLDIHDK_00936 2.61e-96 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
KHLDIHDK_00937 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KHLDIHDK_00938 1.05e-224 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the OMP decarboxylase family. Type 2 subfamily
KHLDIHDK_00939 6.72e-204 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
KHLDIHDK_00940 1.77e-235 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KHLDIHDK_00941 4.64e-160 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHLDIHDK_00942 8.87e-39 - - - - - - - -
KHLDIHDK_00943 3.66e-276 - - - S - - - Psort location Cytoplasmic, score 8.87
KHLDIHDK_00944 1.55e-221 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
KHLDIHDK_00945 1.93e-157 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KHLDIHDK_00946 0.0 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KHLDIHDK_00947 0.0 ybiT - - S ko:K06158 - ko00000,ko03012 ABC transporter
KHLDIHDK_00948 6.37e-169 - - - S - - - Enoyl-(Acyl carrier protein) reductase
KHLDIHDK_00949 6.87e-72 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KHLDIHDK_00950 1.63e-30 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KHLDIHDK_00951 9.42e-35 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KHLDIHDK_00952 7.51e-121 - - - S ko:K16926 - ko00000,ko00002,ko02000 Hypothetical bacterial integral membrane protein (Trep_Strep)
KHLDIHDK_00953 1.43e-296 - 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Psort location Cytoplasmic, score 8.87
KHLDIHDK_00954 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KHLDIHDK_00955 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KHLDIHDK_00956 4.2e-240 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate dehydrogenase substrate binding domain
KHLDIHDK_00957 3.82e-229 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KHLDIHDK_00958 2.86e-217 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KHLDIHDK_00959 1.3e-281 pgk 2.7.2.3, 5.3.1.1 - F ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglycerate kinase
KHLDIHDK_00960 1.7e-188 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KHLDIHDK_00961 2.51e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
KHLDIHDK_00962 7.97e-224 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
KHLDIHDK_00963 9.92e-206 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KHLDIHDK_00964 0.0 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase, class I II
KHLDIHDK_00965 9.16e-251 - - - - - - - -
KHLDIHDK_00966 1.49e-307 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KHLDIHDK_00967 2.71e-259 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KHLDIHDK_00968 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
KHLDIHDK_00969 4.92e-245 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KHLDIHDK_00970 2.29e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KHLDIHDK_00971 7.54e-200 - - - G - - - Fructosamine kinase
KHLDIHDK_00972 1.51e-201 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KHLDIHDK_00973 3.08e-169 - - - S - - - PAC2 family
KHLDIHDK_00979 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHLDIHDK_00980 3.93e-145 - 2.7.7.53 - FG ko:K19710 ko00230,map00230 ko00000,ko00001,ko01000 HIT domain
KHLDIHDK_00981 1.19e-156 yebC - - K - - - transcriptional regulatory protein
KHLDIHDK_00982 4.21e-131 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KHLDIHDK_00983 5.65e-136 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KHLDIHDK_00984 1.5e-254 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KHLDIHDK_00985 6.21e-72 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit
KHLDIHDK_00986 3.21e-130 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHLDIHDK_00987 2.42e-281 sucC 6.2.1.5 - F ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KHLDIHDK_00988 3.58e-209 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KHLDIHDK_00989 1.14e-295 - - - - - - - -
KHLDIHDK_00990 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
KHLDIHDK_00991 4.32e-44 - - - - - - - -
KHLDIHDK_00992 1.34e-181 - - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KHLDIHDK_00993 1.57e-184 rluB 5.4.99.19, 5.4.99.22 - J ko:K06178,ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KHLDIHDK_00994 0.0 der - - F ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KHLDIHDK_00996 3.75e-208 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KHLDIHDK_00997 0.0 ugp 2.7.7.9 - G ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KHLDIHDK_00998 0.0 - - - K - - - WYL domain
KHLDIHDK_00999 4.22e-70 - - - - - - - -
KHLDIHDK_01000 0.0 helY - - L ko:K03727 - ko00000,ko01000 DEAD DEAH box helicase
KHLDIHDK_01001 3.18e-81 rbpA - - K - - - Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
KHLDIHDK_01002 2.61e-179 nt5e 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
KHLDIHDK_01003 1.16e-48 - - - - - - - -
KHLDIHDK_01004 5.1e-83 - - - - - - - -
KHLDIHDK_01005 3.85e-144 merR2 - - K - - - helix_turn_helix, mercury resistance
KHLDIHDK_01006 2.02e-97 garA - - T - - - Inner membrane component of T3SS, cytoplasmic domain
KHLDIHDK_01007 1.13e-181 - - - S - - - Bacterial protein of unknown function (DUF881)
KHLDIHDK_01008 6.08e-61 sbp - - S - - - Protein of unknown function (DUF1290)
KHLDIHDK_01009 7.29e-220 - - - S - - - Bacterial protein of unknown function (DUF881)
KHLDIHDK_01010 2.23e-136 pgsA2 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHLDIHDK_01011 3.56e-199 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
KHLDIHDK_01012 5.07e-56 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-ATP pyrophosphohydrolase
KHLDIHDK_01013 8.36e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3-epimerase
KHLDIHDK_01014 4.91e-239 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KHLDIHDK_01015 4.36e-208 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KHLDIHDK_01016 0.0 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KHLDIHDK_01017 4.59e-162 - - - S - - - SOS response associated peptidase (SRAP)
KHLDIHDK_01018 3.3e-200 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KHLDIHDK_01019 0.0 - - - E ko:K16235 - ko00000,ko02000 amino acid
KHLDIHDK_01020 4.91e-240 - - - V - - - VanZ like family
KHLDIHDK_01021 2.41e-82 cefD 5.1.1.17 - E ko:K04127 ko00311,ko01100,ko01130,map00311,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Aminotransferase, class V
KHLDIHDK_01022 1.1e-129 - - - S - - - Acetyltransferase (GNAT) domain
KHLDIHDK_01023 1.5e-65 - - - - - - - -
KHLDIHDK_01024 1.39e-155 - - - - - - - -
KHLDIHDK_01027 6.82e-19 - - - T - - - Histidine kinase
KHLDIHDK_01028 3.3e-261 - - - T - - - Histidine kinase
KHLDIHDK_01029 3.69e-166 - - - K - - - helix_turn_helix, Lux Regulon
KHLDIHDK_01030 5.1e-125 - - - - - - - -
KHLDIHDK_01031 1.68e-199 - - - M - - - Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KHLDIHDK_01032 7.75e-161 - - - Q ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_01033 1.83e-233 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
KHLDIHDK_01034 1.27e-54 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
KHLDIHDK_01035 1.04e-64 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
KHLDIHDK_01036 3.5e-120 - - - K ko:K03088 - ko00000,ko03021 Sigma-70 region 2
KHLDIHDK_01038 8.36e-138 - - - - - - - -
KHLDIHDK_01039 3.2e-170 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
KHLDIHDK_01040 1.58e-206 - - - V - - - ATPases associated with a variety of cellular activities
KHLDIHDK_01041 1.22e-93 - - - - - - - -
KHLDIHDK_01042 4.62e-81 - - - - - - - -
KHLDIHDK_01043 2.27e-190 - - - S ko:K11939 - ko00000,ko02000 EamA-like transporter family
KHLDIHDK_01044 1.88e-129 - - - - - - - -
KHLDIHDK_01045 1.74e-165 - - - - - - - -
KHLDIHDK_01046 1.06e-154 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_01047 2.36e-73 - - - L - - - Transposase and inactivated derivatives IS30 family
KHLDIHDK_01048 2.89e-112 - - - L - - - Transposase and inactivated derivatives IS30 family
KHLDIHDK_01049 2.05e-154 - - - K - - - Bacterial regulatory proteins, luxR family
KHLDIHDK_01050 6.48e-286 - - - T - - - Histidine kinase
KHLDIHDK_01051 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
KHLDIHDK_01052 6.69e-208 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KHLDIHDK_01054 1.11e-65 - - - S - - - Protein of unknown function (DUF2089)
KHLDIHDK_01055 8.18e-70 - - - - - - - -
KHLDIHDK_01056 2.52e-93 - - - K - - - Transcriptional regulator
KHLDIHDK_01057 3.98e-143 - - - - - - - -
KHLDIHDK_01058 9.63e-61 - - - K ko:K20391 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
KHLDIHDK_01059 1.32e-45 hipA 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 kinase activity
KHLDIHDK_01060 2.62e-55 - - - EGP - - - Major Facilitator Superfamily
KHLDIHDK_01061 1.77e-27 - - - G - - - Major facilitator Superfamily
KHLDIHDK_01062 0.0 - - - E ko:K16235 - ko00000,ko02000 amino acid
KHLDIHDK_01063 5.66e-13 - - - - - - - -
KHLDIHDK_01064 7.04e-82 - - - K - - - Protein of unknown function, DUF488
KHLDIHDK_01065 4.83e-98 - - - - - - - -
KHLDIHDK_01066 3.67e-231 - - - - - - - -
KHLDIHDK_01067 9.46e-119 - - - S ko:K09974 - ko00000 Domain of unknown function (DUF1287)
KHLDIHDK_01068 0.0 trpE 4.1.3.27 - E ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KHLDIHDK_01069 2.28e-93 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KHLDIHDK_01070 4.13e-180 hisF 4.1.3.27 - E ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KHLDIHDK_01071 8.15e-98 - 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
KHLDIHDK_01072 1.36e-286 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KHLDIHDK_01073 8.23e-223 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Cytidylyltransferase family
KHLDIHDK_01074 7.06e-120 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KHLDIHDK_01075 3.81e-171 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KHLDIHDK_01076 1.6e-186 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHLDIHDK_01077 2.69e-192 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KHLDIHDK_01078 1.96e-113 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KHLDIHDK_01079 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 long-chain-fatty acid CoA ligase
KHLDIHDK_01080 5.83e-120 - - - - - - - -
KHLDIHDK_01081 8.81e-264 guaB3 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 IMP dehydrogenase family protein
KHLDIHDK_01082 8.16e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the isocitrate and isopropylmalate dehydrogenases family
KHLDIHDK_01083 0.0 - - - G - - - ABC transporter substrate-binding protein
KHLDIHDK_01084 2.35e-47 - - - M - - - Peptidase family M23
KHLDIHDK_01086 2.65e-43 - - - L - - - Phage integrase family
KHLDIHDK_01087 3.22e-25 - 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 HipA-like C-terminal domain
KHLDIHDK_01088 5.24e-185 - - - S - - - Fic/DOC family
KHLDIHDK_01089 6.62e-70 - - - L - - - PFAM Relaxase mobilization nuclease family protein
KHLDIHDK_01090 1.89e-253 - - - V ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KHLDIHDK_01091 2.53e-181 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KHLDIHDK_01092 4.89e-183 - - - - ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
KHLDIHDK_01093 3.84e-91 - - - - - - - -
KHLDIHDK_01095 9.59e-305 - - - T - - - Histidine kinase
KHLDIHDK_01096 1.49e-154 - - - K - - - helix_turn_helix, Lux Regulon
KHLDIHDK_01098 6.28e-248 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHLDIHDK_01099 1.16e-135 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 FR47-like protein
KHLDIHDK_01100 1.45e-203 yeaZ - - O ko:K14742 - ko00000,ko03016 Glycoprotease family
KHLDIHDK_01101 2.49e-111 tsaE - - S ko:K06925 - ko00000,ko03016 Threonylcarbamoyl adenosine biosynthesis protein TsaE
KHLDIHDK_01102 2.06e-220 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KHLDIHDK_01103 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein
KHLDIHDK_01104 8.17e-84 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Helix-hairpin-helix motif
KHLDIHDK_01105 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KHLDIHDK_01106 2.62e-206 - - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KHLDIHDK_01107 4.06e-217 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
KHLDIHDK_01108 2.1e-215 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
KHLDIHDK_01109 2.45e-295 - - - L - - - ribosomal rna small subunit methyltransferase
KHLDIHDK_01110 2.35e-92 pdxH - - S ko:K07006 - ko00000 Pfam:Pyridox_oxidase
KHLDIHDK_01111 3.5e-220 - - - EG - - - EamA-like transporter family
KHLDIHDK_01112 6.15e-170 - - - C - - - Putative TM nitroreductase
KHLDIHDK_01113 1.16e-41 - - - - - - - -
KHLDIHDK_01115 0.0 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
KHLDIHDK_01116 9.53e-305 - - - G - - - N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KHLDIHDK_01117 1.14e-169 - - - L - - - PFAM Integrase catalytic
KHLDIHDK_01118 8.7e-94 - - - L - - - PFAM Integrase catalytic
KHLDIHDK_01119 2.93e-175 - - - K - - - helix_turn _helix lactose operon repressor
KHLDIHDK_01120 1.62e-278 - - - G - - - Belongs to the glycosyl hydrolase 5 (cellulase A) family
KHLDIHDK_01121 8.07e-160 - - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01122 5.02e-155 - - - G ko:K02025,ko:K17330 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01123 5.09e-223 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_01124 0.0 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase, middle domain
KHLDIHDK_01125 0.0 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase, middle domain
KHLDIHDK_01126 7.94e-109 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KHLDIHDK_01127 1.07e-94 - - - S - - - von Willebrand factor (vWF) type A domain
KHLDIHDK_01128 2.74e-64 lppD - - S - - - Appr-1'-p processing enzyme
KHLDIHDK_01129 2.46e-54 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
KHLDIHDK_01130 1.53e-78 - - - L ko:K07483 - ko00000 Integrase core domain
KHLDIHDK_01131 0.0 - - - EGP - - - Major Facilitator Superfamily
KHLDIHDK_01132 3.98e-18 - - - IQ - - - [acyl-carrier-protein] S-malonyltransferase activity
KHLDIHDK_01133 9.86e-58 - - - H - - - Beta-ketoacyl synthase, C-terminal domain
KHLDIHDK_01134 4.51e-148 - - - K - - - WHG domain
KHLDIHDK_01135 7.83e-120 - - - Q - - - 4'-phosphopantetheinyl transferase superfamily
KHLDIHDK_01136 1.53e-78 - - - L ko:K07483 - ko00000 Integrase core domain
KHLDIHDK_01137 1.43e-53 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
KHLDIHDK_01138 4.36e-203 - - - S - - - Fic/DOC family
KHLDIHDK_01139 9.51e-317 - - - S - - - HipA-like C-terminal domain
KHLDIHDK_01141 1.31e-98 - - - - - - - -
KHLDIHDK_01142 0.0 intA - - L - - - Phage integrase family
KHLDIHDK_01143 1.15e-183 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
KHLDIHDK_01144 2.17e-35 - - - - - - - -
KHLDIHDK_01145 9.95e-70 - - - - - - - -
KHLDIHDK_01146 2.22e-78 - - - - - - - -
KHLDIHDK_01147 8.25e-85 - - - - - - - -
KHLDIHDK_01150 0.0 - 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase
KHLDIHDK_01151 2.16e-83 - - - - - - - -
KHLDIHDK_01154 1.84e-59 - - - S - - - Domain of unknown function (DUF4160)
KHLDIHDK_01155 2.05e-55 - - - K - - - Protein of unknown function (DUF2442)
KHLDIHDK_01156 2.61e-83 - - - S - - - Bacterial mobilisation protein (MobC)
KHLDIHDK_01157 0.0 - - - U - - - Relaxase/Mobilisation nuclease domain
KHLDIHDK_01158 2.97e-185 - - - S - - - Protein of unknown function (DUF3801)
KHLDIHDK_01160 1.06e-68 - - - - - - - -
KHLDIHDK_01161 4.37e-59 - - - - - - - -
KHLDIHDK_01162 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Type IV secretory system Conjugative DNA transfer
KHLDIHDK_01164 2.19e-128 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 D12 class N6 adenine-specific DNA methyltransferase
KHLDIHDK_01165 6.99e-122 - - - K - - - DNA binding
KHLDIHDK_01166 2.95e-185 - - - - ko:K03646 - ko00000,ko02000 -
KHLDIHDK_01167 1.69e-125 - - - - - - - -
KHLDIHDK_01168 0.0 - - - M - - - CHAP domain
KHLDIHDK_01169 0.0 - - - U - - - type IV secretory pathway VirB4
KHLDIHDK_01170 5.06e-83 - - - S - - - PrgI family protein
KHLDIHDK_01171 1.95e-186 - - - - - - - -
KHLDIHDK_01172 5.33e-36 - - - - - - - -
KHLDIHDK_01173 0.0 - - - D - - - Cell surface antigen C-terminus
KHLDIHDK_01174 1.43e-51 - - - - ko:K03646 - ko00000,ko02000 -
KHLDIHDK_01176 2.5e-40 - - - - - - - -
KHLDIHDK_01177 1.22e-146 - - - D ko:K03496 - ko00000,ko03036,ko04812 AAA domain
KHLDIHDK_01178 2.36e-116 - - - S - - - Transcription factor WhiB
KHLDIHDK_01179 1.84e-55 - - - - - - - -
KHLDIHDK_01180 2.34e-55 - - - S - - - Helix-turn-helix domain
KHLDIHDK_01181 1.51e-142 - - - S - - - Helix-turn-helix domain
KHLDIHDK_01182 5.31e-22 - - - - - - - -
KHLDIHDK_01183 2.25e-37 - - - - - - - -
KHLDIHDK_01185 2.45e-86 - - - - - - - -
KHLDIHDK_01186 0.000744 - - - K - - - Helix-turn-helix XRE-family like proteins
KHLDIHDK_01187 6.18e-146 ppiA 5.2.1.8 - G ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHLDIHDK_01188 0.0 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHLDIHDK_01189 7.13e-110 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KHLDIHDK_01190 4.95e-63 - - - S - - - Domain of unknown function (DUF4193)
KHLDIHDK_01191 6.14e-212 - - - S - - - Protein of unknown function (DUF3071)
KHLDIHDK_01192 8.52e-298 - - - S - - - Type I phosphodiesterase / nucleotide pyrophosphatase
KHLDIHDK_01193 0.0 gyrA2 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
KHLDIHDK_01197 0.0 lhr - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
KHLDIHDK_01198 2.86e-219 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHLDIHDK_01199 2.53e-284 - - - G - - - Major Facilitator Superfamily
KHLDIHDK_01200 0.0 gyrB2 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
KHLDIHDK_01201 1.24e-248 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KHLDIHDK_01202 2.92e-147 - - - - - - - -
KHLDIHDK_01203 4.11e-252 idsA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KHLDIHDK_01204 0.0 pknL 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 PASTA
KHLDIHDK_01205 1.14e-167 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
KHLDIHDK_01206 8.99e-157 - - - - - - - -
KHLDIHDK_01207 4.39e-244 trpD 2.4.2.18 - F ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KHLDIHDK_01208 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KHLDIHDK_01209 1.24e-154 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KHLDIHDK_01210 1.58e-133 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
KHLDIHDK_01211 1.29e-261 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHLDIHDK_01212 9.29e-52 - - - S - - - Protein of unknown function (DUF3046)
KHLDIHDK_01213 4.65e-101 - - - K - - - Helix-turn-helix XRE-family like proteins
KHLDIHDK_01214 3.95e-127 cinA 3.5.1.42 - S ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
KHLDIHDK_01215 1.04e-152 pgsA 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHLDIHDK_01216 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 FtsK SpoIIIE family protein
KHLDIHDK_01217 6.42e-192 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
KHLDIHDK_01218 7.74e-232 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHLDIHDK_01219 0.0 miaB 2.8.4.3 - H ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KHLDIHDK_01220 2.71e-190 ywaC 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
KHLDIHDK_01221 2.75e-212 - - - EG - - - EamA-like transporter family
KHLDIHDK_01222 4.02e-175 - - - S ko:K06890 - ko00000 Belongs to the BI1 family
KHLDIHDK_01223 1.12e-106 - - - K - - - helix_turn_helix, Lux Regulon
KHLDIHDK_01224 2.33e-155 - - - E - - - Psort location Cytoplasmic, score 8.87
KHLDIHDK_01225 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KHLDIHDK_01226 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
KHLDIHDK_01227 5.51e-127 - - - - - - - -
KHLDIHDK_01228 2.64e-306 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHLDIHDK_01229 2.99e-174 - - - S - - - Protein of unknown function (DUF3159)
KHLDIHDK_01230 6.9e-196 - - - S - - - Protein of unknown function (DUF3710)
KHLDIHDK_01231 1.13e-217 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease/Exonuclease/phosphatase family
KHLDIHDK_01232 0.0 - - - EP ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
KHLDIHDK_01233 2.81e-233 dppC - - EP ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
KHLDIHDK_01234 1.39e-204 dppB - - EP ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01235 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
KHLDIHDK_01236 1.41e-240 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
KHLDIHDK_01237 1.06e-189 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHLDIHDK_01238 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
KHLDIHDK_01239 2.76e-55 - - - - - - - -
KHLDIHDK_01240 4.06e-244 tyrA 1.3.1.12 - E ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydrogenase
KHLDIHDK_01241 7.57e-240 pheA 4.2.1.51, 5.4.99.5 - E ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
KHLDIHDK_01242 2.23e-102 - - - - - - - -
KHLDIHDK_01243 0.0 typA - - T ko:K06207 - ko00000 Elongation factor G C-terminus
KHLDIHDK_01244 1.46e-139 - - - K - - - Virulence activator alpha C-term
KHLDIHDK_01245 5.21e-177 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_01246 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KHLDIHDK_01247 4.83e-24 nanT - - U ko:K03290,ko:K08178,ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
KHLDIHDK_01248 2.45e-304 iscS1 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
KHLDIHDK_01249 3.73e-208 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate phosphoribosyl transferase, N-terminal domain
KHLDIHDK_01250 0.0 nadB 1.4.3.16, 2.4.2.19 - H ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
KHLDIHDK_01251 0.0 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KHLDIHDK_01252 3.89e-205 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX hydrolase
KHLDIHDK_01253 1.81e-149 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KHLDIHDK_01254 9.39e-195 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KHLDIHDK_01255 2.4e-193 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
KHLDIHDK_01256 4.74e-200 xerD - - D ko:K03733,ko:K04763 - ko00000,ko03036 recombinase XerD
KHLDIHDK_01257 1.61e-271 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KHLDIHDK_01258 2.6e-79 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHLDIHDK_01259 2.72e-34 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L35
KHLDIHDK_01260 1.41e-156 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHLDIHDK_01261 6.5e-49 - - - S - - - Spermine/spermidine synthase domain
KHLDIHDK_01262 5.45e-173 - 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiamin pyrophosphokinase, vitamin B1 binding domain
KHLDIHDK_01263 1.23e-252 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KHLDIHDK_01264 4.92e-115 ybaK - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHLDIHDK_01265 5.06e-234 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KHLDIHDK_01266 1.72e-244 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KHLDIHDK_01267 1.64e-240 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KHLDIHDK_01268 3.96e-69 - - - - - - - -
KHLDIHDK_01269 1.11e-176 sigH - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KHLDIHDK_01270 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHLDIHDK_01271 1.27e-250 - - - V - - - Acetyltransferase (GNAT) domain
KHLDIHDK_01272 1.36e-105 - - - V - - - Acetyltransferase (GNAT) domain
KHLDIHDK_01273 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KHLDIHDK_01274 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Mur ligase middle domain
KHLDIHDK_01275 0.0 pepP 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Aminopeptidase P, N-terminal domain
KHLDIHDK_01276 1.58e-127 - - - F - - - NUDIX domain
KHLDIHDK_01277 5.02e-314 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
KHLDIHDK_01278 9.44e-193 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KHLDIHDK_01279 2.75e-267 - - - GK - - - ROK family
KHLDIHDK_01280 2e-211 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KHLDIHDK_01281 1.31e-287 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KHLDIHDK_01282 1.66e-216 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
KHLDIHDK_01283 2.55e-52 - - - G - - - Major Facilitator Superfamily
KHLDIHDK_01284 4.32e-97 - - - G - - - Major Facilitator Superfamily
KHLDIHDK_01285 2.94e-110 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KHLDIHDK_01286 1e-162 int8 - - L - - - Phage integrase family
KHLDIHDK_01289 5.34e-38 - - - K - - - Transcriptional regulator
KHLDIHDK_01290 6.72e-68 - - - - - - - -
KHLDIHDK_01291 3.11e-21 - - - - - - - -
KHLDIHDK_01292 4.07e-95 - - - V - - - Ami_2
KHLDIHDK_01298 2.09e-49 - - - - - - - -
KHLDIHDK_01300 0.0 - - - S - - - cellulase activity
KHLDIHDK_01302 3.03e-108 - - - NT - - - phage tail tape measure protein
KHLDIHDK_01304 9.34e-38 - - - - - - - -
KHLDIHDK_01307 3.19e-40 - - - - - - - -
KHLDIHDK_01308 3.04e-33 - - - - - - - -
KHLDIHDK_01309 1.24e-40 - - - - - - - -
KHLDIHDK_01310 5.15e-24 - - - - - - - -
KHLDIHDK_01312 3.68e-140 - - - S - - - Phage capsid family
KHLDIHDK_01314 4.48e-80 - - - S - - - Phage portal protein
KHLDIHDK_01315 0.0 - - - S - - - Terminase
KHLDIHDK_01316 8.95e-57 - - - - - - - -
KHLDIHDK_01319 9.01e-156 - - - - - - - -
KHLDIHDK_01320 2.87e-22 - - - - - - - -
KHLDIHDK_01325 1.54e-94 - - - - - - - -
KHLDIHDK_01326 1.65e-55 - - - D - - - DNA N-6-adenine-methyltransferase (Dam)
KHLDIHDK_01331 1.36e-65 - - - - - - - -
KHLDIHDK_01332 5.84e-82 - - - - - - - -
KHLDIHDK_01333 7.38e-67 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
KHLDIHDK_01335 4.35e-91 - - - L ko:K07455 - ko00000,ko03400 RecT family
KHLDIHDK_01336 4.43e-105 - - - L - - - YqaJ-like viral recombinase domain
KHLDIHDK_01339 4.82e-06 - - - K - - - Helix-turn-helix domain
KHLDIHDK_01340 2.47e-131 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
KHLDIHDK_01341 7.78e-89 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
KHLDIHDK_01343 3.18e-62 - - - Q - - - methyltransferase
KHLDIHDK_01348 7.16e-62 - - - - - - - -
KHLDIHDK_01350 3.3e-82 - - - - - - - -
KHLDIHDK_01352 1.95e-229 ftsQ - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein FtsQ
KHLDIHDK_01353 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KHLDIHDK_01354 1.24e-278 murG 2.4.1.227, 6.3.2.8 GT28 M ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHLDIHDK_01355 4.95e-288 ftsW 2.4.1.227 GT28 D ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 Belongs to the SEDS family
KHLDIHDK_01356 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHLDIHDK_01357 3.33e-265 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHLDIHDK_01358 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KHLDIHDK_01359 2.6e-200 - - - M - - - Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHLDIHDK_01360 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding protein, transpeptidase domain protein
KHLDIHDK_01361 2.61e-90 - - - D - - - Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KHLDIHDK_01362 1.21e-242 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KHLDIHDK_01363 2.33e-120 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
KHLDIHDK_01364 0.0 - - - L - - - DNA helicase
KHLDIHDK_01365 4.79e-292 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
KHLDIHDK_01366 4.08e-101 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KHLDIHDK_01367 7.41e-70 - - - M - - - Lysin motif
KHLDIHDK_01368 3.03e-168 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHLDIHDK_01369 1.39e-207 czcD - - P ko:K16264 - ko00000,ko02000 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KHLDIHDK_01370 1.61e-225 ldh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KHLDIHDK_01371 0.0 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHLDIHDK_01372 1.99e-159 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase (PrmA)
KHLDIHDK_01373 0.0 hrpA 3.6.4.13 - L ko:K03578 - ko00000,ko01000 Helicase associated domain (HA2) Add an annotation
KHLDIHDK_01374 4.33e-280 - - - EGP ko:K18567,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
KHLDIHDK_01375 0.0 glnA2 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KHLDIHDK_01376 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2252)
KHLDIHDK_01377 1.18e-167 hisA 5.3.1.16, 5.3.1.24 - E ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis protein
KHLDIHDK_01378 2.07e-155 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KHLDIHDK_01379 2.17e-162 - - - - - - - -
KHLDIHDK_01380 4.75e-144 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Imidazoleglycerol-phosphate dehydratase
KHLDIHDK_01381 1.57e-279 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KHLDIHDK_01382 0.0 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KHLDIHDK_01383 4.18e-71 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Acylphosphatase
KHLDIHDK_01384 3.87e-199 - - - S - - - Aldo/keto reductase family
KHLDIHDK_01385 0.0 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65, N-terminal domain
KHLDIHDK_01386 4.23e-214 - 4.1.2.28 - EM ko:K22397 ko00040,map00040 ko00000,ko00001,ko01000 Dihydrodipicolinate synthetase family
KHLDIHDK_01387 2.92e-193 - - - S - - - Amidohydrolase
KHLDIHDK_01388 1.49e-181 - 1.1.1.100, 1.1.1.413 - IQ ko:K00059,ko:K18333,ko:K22322 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
KHLDIHDK_01389 3.44e-211 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Enolase C-terminal domain-like
KHLDIHDK_01391 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
KHLDIHDK_01392 1.54e-214 dkgV - - C - - - Aldo/keto reductase family
KHLDIHDK_01394 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
KHLDIHDK_01395 2.13e-256 - - - K - - - WYL domain
KHLDIHDK_01396 4.29e-227 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KHLDIHDK_01397 1.72e-116 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KHLDIHDK_01398 3.75e-88 - - - V - - - DivIVA protein
KHLDIHDK_01399 3.44e-60 - - - S ko:K02221 - ko00000,ko02044 YGGT family
KHLDIHDK_01400 2.98e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KHLDIHDK_01401 7.1e-274 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHLDIHDK_01402 2.02e-316 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHLDIHDK_01403 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
KHLDIHDK_01404 3.89e-198 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KHLDIHDK_01405 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KHLDIHDK_01406 1.37e-292 - - - O ko:K13525 ko04141,ko05134,map04141,map05134 ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 AAA domain (Cdc48 subfamily)
KHLDIHDK_01407 2.14e-187 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KHLDIHDK_01408 1.64e-81 - - - S - - - Thiamine-binding protein
KHLDIHDK_01409 0.0 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
KHLDIHDK_01410 1.86e-293 - - - T - - - Histidine kinase
KHLDIHDK_01411 5.01e-159 - - - K - - - helix_turn_helix, Lux Regulon
KHLDIHDK_01412 2.01e-244 - - - - - - - -
KHLDIHDK_01413 0.0 - - - O ko:K13963 ko05146,map05146 ko00000,ko00001 SERine Proteinase INhibitors
KHLDIHDK_01414 2.26e-241 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHLDIHDK_01415 1.8e-306 lacY - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
KHLDIHDK_01416 0.0 fosC 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
KHLDIHDK_01417 6.61e-181 ppgK 2.7.1.2, 2.7.1.63 - GK ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KHLDIHDK_01418 8.77e-193 - - - C - - - Putative TM nitroreductase
KHLDIHDK_01419 1.55e-252 - - - S - - - Glycosyltransferase, group 2 family protein
KHLDIHDK_01420 4.04e-134 - - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHLDIHDK_01421 0.0 - - - GP ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KHLDIHDK_01422 4.67e-63 - - - J ko:K07574 - ko00000,ko03009 CRS1_YhbY
KHLDIHDK_01423 7.05e-72 - - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
KHLDIHDK_01424 1.94e-68 - - - - - - - -
KHLDIHDK_01425 4.03e-239 - - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KHLDIHDK_01426 0.0 - - - EGP - - - Major Facilitator Superfamily
KHLDIHDK_01427 2.13e-40 mtrB 2.7.13.3 - T ko:K07636,ko:K07654 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KHLDIHDK_01428 2.53e-14 mtrA - - KT ko:K07670 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
KHLDIHDK_01429 0.0 rarA - - L ko:K07478 - ko00000 Recombination factor protein RarA
KHLDIHDK_01430 0.0 - - - L - - - DEAD DEAH box helicase
KHLDIHDK_01431 2.54e-255 - - - S - - - Polyphosphate kinase 2 (PPK2)
KHLDIHDK_01433 0.0 - - - EK ko:K05825,ko:K18907 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko00002,ko01000,ko01504,ko03000 Alanine-glyoxylate amino-transferase
KHLDIHDK_01434 1.13e-145 - - - S ko:K06895 - ko00000,ko02000 LysE type translocator
KHLDIHDK_01435 0.0 - - - I - - - PAP2 superfamily
KHLDIHDK_01436 2.11e-251 gluD - - E ko:K10007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01437 8.52e-144 gluC - - E ko:K10006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01438 3.16e-189 gluB - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KHLDIHDK_01439 9.45e-198 gluA - - E ko:K10008 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding protein of ABC transporter for glutamate K02028
KHLDIHDK_01440 4.46e-132 - - - S - - - Aminoacyl-tRNA editing domain
KHLDIHDK_01441 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KHLDIHDK_01442 0.0 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Histidyl-tRNA synthetase
KHLDIHDK_01443 0.0 - - - S - - - Domain of Unknown Function (DUF349)
KHLDIHDK_01444 0.0 - 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
KHLDIHDK_01445 1.83e-181 - 3.5.2.10 - S ko:K01470 ko00330,map00330 ko00000,ko00001,ko01000 Creatinine amidohydrolase
KHLDIHDK_01446 9.08e-317 proP - - EGP ko:K03762 - ko00000,ko02000 Sugar (and other) transporter
KHLDIHDK_01448 0.0 - - - QT - - - Purine catabolism regulatory protein-like family
KHLDIHDK_01449 0.0 codA 3.5.4.1, 3.5.4.21 - F ko:K01485,ko:K03365 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 Amidohydrolase family
KHLDIHDK_01450 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
KHLDIHDK_01451 6.44e-174 uspA - - T - - - Belongs to the universal stress protein A family
KHLDIHDK_01452 8.27e-40 uspA - - T - - - Belongs to the universal stress protein A family
KHLDIHDK_01453 4.74e-244 - - - S - - - Protein of unknown function (DUF3027)
KHLDIHDK_01454 1.75e-87 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
KHLDIHDK_01455 0.0 phoR 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
KHLDIHDK_01456 1.23e-170 phoP - - KT ko:K02483 - ko00000,ko02022 Response regulator receiver domain protein
KHLDIHDK_01457 3.1e-147 - - - - - - - -
KHLDIHDK_01458 6.57e-54 - - - S - - - Proteins of 100 residues with WXG
KHLDIHDK_01459 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KHLDIHDK_01460 1.54e-51 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
KHLDIHDK_01461 9.7e-126 - - - S - - - LytR cell envelope-related transcriptional attenuator
KHLDIHDK_01462 2.32e-168 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHLDIHDK_01463 1.08e-245 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
KHLDIHDK_01464 3.97e-210 - - - S - - - Protein of unknown function DUF58
KHLDIHDK_01465 1.88e-118 - - - - - - - -
KHLDIHDK_01466 2.25e-241 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
KHLDIHDK_01467 1.27e-214 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
KHLDIHDK_01468 1.42e-74 - - - - - - - -
KHLDIHDK_01469 0.0 - - - S - - - PGAP1-like protein
KHLDIHDK_01470 3.68e-144 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
KHLDIHDK_01471 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminal
KHLDIHDK_01472 0.0 - - - S - - - Lysylphosphatidylglycerol synthase TM region
KHLDIHDK_01473 3.31e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
KHLDIHDK_01474 0.0 pafA 6.3.1.19 - O ko:K13571 - ko00000,ko00002,ko01000,ko03051 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KHLDIHDK_01475 8.43e-16 pup - - S ko:K13570 - ko00000,ko04121 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
KHLDIHDK_01476 4.8e-224 - 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase family
KHLDIHDK_01477 0.0 dop 3.5.1.119 - S ko:K20814 - ko00000,ko01000,ko03051 Pup-ligase protein
KHLDIHDK_01478 1.06e-173 - - - G ko:K17195 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Ribulose-phosphate 3 epimerase family
KHLDIHDK_01479 9.78e-228 - - - G ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase System
KHLDIHDK_01480 2.2e-62 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KHLDIHDK_01481 4.66e-105 - 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHLDIHDK_01482 1.33e-95 - - - H - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHLDIHDK_01483 0.0 - - - K ko:K02538,ko:K03483,ko:K03491 - ko00000,ko03000 PRD domain
KHLDIHDK_01484 4.67e-172 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KHLDIHDK_01485 0.0 arc - - O ko:K13527 ko03050,map03050 ko00000,ko00001,ko00002,ko03051 AAA ATPase forming ring-shaped complexes
KHLDIHDK_01486 2.05e-163 - - - S - - - SNARE associated Golgi protein
KHLDIHDK_01487 3.51e-155 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 haloacid dehalogenase-like hydrolase
KHLDIHDK_01488 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHLDIHDK_01489 6.15e-171 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KHLDIHDK_01490 2.96e-241 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHLDIHDK_01491 0.0 ilvD 4.2.1.9 - H ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
KHLDIHDK_01492 5.45e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KHLDIHDK_01493 2.77e-290 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHLDIHDK_01494 1.71e-133 - - - L - - - Belongs to the 'phage' integrase family
KHLDIHDK_01495 1.18e-99 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
KHLDIHDK_01496 3.16e-306 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
KHLDIHDK_01497 0.0 - 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
KHLDIHDK_01499 8.48e-203 - - - I - - - type I phosphodiesterase nucleotide pyrophosphatase
KHLDIHDK_01500 8.43e-261 - - - E ko:K02052 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KHLDIHDK_01501 1.19e-205 - - - U ko:K02053 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01502 1.14e-199 - - - U ko:K02054 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01503 4.88e-261 - - - P ko:K02055 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_01504 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KHLDIHDK_01505 9.93e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHLDIHDK_01506 3.27e-200 - - - C ko:K03326 - ko00000,ko02000 C4-dicarboxylate anaerobic carrier
KHLDIHDK_01507 1.99e-131 rihA - - F ko:K01250,ko:K12700 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
KHLDIHDK_01508 1.58e-56 - - - K - - - acetyltransferase
KHLDIHDK_01509 6.13e-160 rbsR - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHLDIHDK_01510 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
KHLDIHDK_01511 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
KHLDIHDK_01512 1.23e-117 - - - K - - - MarR family
KHLDIHDK_01513 0.0 bglB 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
KHLDIHDK_01514 1.39e-110 - - - K - - - Bacterial regulatory proteins, tetR family
KHLDIHDK_01515 3.29e-269 - 3.2.1.4, 3.2.1.58 GH5,GH9 G ko:K01179,ko:K01210 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 5 (cellulase A) family
KHLDIHDK_01516 7.61e-93 - - - S - - - Nucleotidyltransferase substrate binding protein like
KHLDIHDK_01517 4.12e-61 - - - S - - - Nucleotidyltransferase domain
KHLDIHDK_01519 0.0 bgl2 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
KHLDIHDK_01520 5.49e-183 - - - K - - - Bacterial regulatory proteins, tetR family
KHLDIHDK_01521 0.0 egtA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Glutamate-cysteine ligase family 2(GCS2)
KHLDIHDK_01522 0.0 hgdC - - I - - - CoA enzyme activase uncharacterised domain (DUF2229)
KHLDIHDK_01523 1.89e-173 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KHLDIHDK_01524 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
KHLDIHDK_01525 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHLDIHDK_01526 1.7e-55 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHLDIHDK_01527 3.25e-116 ywrO - - S - - - Flavodoxin-like fold
KHLDIHDK_01528 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
KHLDIHDK_01529 8.52e-91 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KHLDIHDK_01530 1.28e-102 - - - F - - - Nucleoside 2-deoxyribosyltransferase
KHLDIHDK_01532 2.41e-259 - - - S ko:K18353 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01504 Endonuclease/Exonuclease/phosphatase family
KHLDIHDK_01533 2.39e-228 ppx1 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
KHLDIHDK_01534 3.68e-298 aspB 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
KHLDIHDK_01535 3.69e-258 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
KHLDIHDK_01536 5.04e-114 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
KHLDIHDK_01537 1.5e-129 - - - K - - - Acetyltransferase (GNAT) domain
KHLDIHDK_01538 0.0 - - - KL - - - Psort location Cytoplasmic, score 8.87
KHLDIHDK_01539 3.06e-219 dapD 2.3.1.117 - E ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
KHLDIHDK_01540 1.06e-315 gltA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Citrate synthase, C-terminal domain
KHLDIHDK_01541 1.25e-192 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
KHLDIHDK_01542 1.38e-197 - - - S - - - Short repeat of unknown function (DUF308)
KHLDIHDK_01543 0.0 pepO 3.4.24.11, 3.4.24.71 - O ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase family M13
KHLDIHDK_01544 8.96e-150 ssb2 - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
KHLDIHDK_01545 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KHLDIHDK_01546 1.03e-197 - 1.97.1.4 - O ko:K04069 - ko00000,ko01000 Radical SAM superfamily
KHLDIHDK_01547 0.0 - - - L - - - PIF1-like helicase
KHLDIHDK_01548 3.86e-156 orn - - L ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
KHLDIHDK_01549 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KHLDIHDK_01550 1.44e-276 rfe 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 4
KHLDIHDK_01551 2.92e-153 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Belongs to the SUA5 family
KHLDIHDK_01552 8.3e-160 livF - - E ko:K01995,ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_01553 2.73e-205 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
KHLDIHDK_01554 3.07e-241 - - - U ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KHLDIHDK_01555 1.08e-196 - - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KHLDIHDK_01556 4.61e-272 - - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
KHLDIHDK_01557 1.59e-212 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KHLDIHDK_01558 1.22e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHLDIHDK_01559 6.44e-49 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
KHLDIHDK_01561 1.35e-136 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
KHLDIHDK_01562 9.48e-194 - - - - - - - -
KHLDIHDK_01563 1.06e-95 fms 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
KHLDIHDK_01564 1.72e-210 dkg - - S - - - Oxidoreductase, aldo keto reductase family protein
KHLDIHDK_01565 9.34e-23 - - - U ko:K08168,ko:K18926 - ko00000,ko00002,ko01504,ko02000 Major Facilitator Superfamily
KHLDIHDK_01566 4.17e-119 - - - K - - - Winged helix DNA-binding domain
KHLDIHDK_01567 9.7e-225 glkA 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KHLDIHDK_01569 0.0 - - - EGP - - - Major Facilitator Superfamily
KHLDIHDK_01570 0.0 yjjK - - S - - - ATP-binding cassette protein, ChvD family
KHLDIHDK_01571 8.55e-216 tesB - - I ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Thioesterase-like superfamily
KHLDIHDK_01572 3.27e-112 - - - S - - - Protein of unknown function (DUF3180)
KHLDIHDK_01573 1.37e-288 folK 2.7.6.3, 4.1.2.25 - H ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KHLDIHDK_01574 9.52e-206 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KHLDIHDK_01575 1.9e-153 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
KHLDIHDK_01576 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHLDIHDK_01577 2.66e-126 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
KHLDIHDK_01578 7.05e-270 tilS 2.4.2.8, 6.3.4.19 - J ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KHLDIHDK_01579 0.0 dacB 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-Ala-D-Ala carboxypeptidase 3 (S13) family
KHLDIHDK_01580 0.0 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
KHLDIHDK_01581 3.89e-244 natA - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_01582 7.16e-298 - - - M - - - Glycosyl transferase family 21
KHLDIHDK_01583 0.0 - - - S - - - AI-2E family transporter
KHLDIHDK_01584 1.09e-226 - - - M - - - Glycosyltransferase like family 2
KHLDIHDK_01585 1.73e-270 fucO 1.1.1.77, 1.1.99.37, 1.2.98.1 - C ko:K00048,ko:K17067 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
KHLDIHDK_01586 0.0 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 Mycolic acid cyclopropane synthetase
KHLDIHDK_01589 3.73e-210 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KHLDIHDK_01591 4.42e-19 - - - L - - - Phage integrase family
KHLDIHDK_01592 0.0 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
KHLDIHDK_01593 0.0 lacZ6 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
KHLDIHDK_01594 2.07e-236 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
KHLDIHDK_01595 1.65e-27 - - - L - - - Helix-turn-helix domain
KHLDIHDK_01596 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_01597 1.34e-278 - - - GK - - - ROK family
KHLDIHDK_01599 0.0 - - - G - - - Glycosyl hydrolase family 20, domain 2
KHLDIHDK_01600 3.13e-10 - - - L - - - HTH-like domain
KHLDIHDK_01601 7.23e-288 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KHLDIHDK_01602 1.37e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
KHLDIHDK_01603 2.92e-144 vex - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHLDIHDK_01604 2.43e-15 - - - E - - - AzlC protein
KHLDIHDK_01605 3.01e-127 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 low molecular weight
KHLDIHDK_01606 1.07e-164 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dihydrofolate reductase
KHLDIHDK_01607 1.73e-214 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHLDIHDK_01608 1.85e-95 - - - O - - - OsmC-like protein
KHLDIHDK_01609 5.52e-241 - - - T - - - Universal stress protein family
KHLDIHDK_01610 6.98e-139 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
KHLDIHDK_01611 1.45e-138 - - - M - - - NlpC/P60 family
KHLDIHDK_01612 2.08e-216 - - - S - - - CHAP domain
KHLDIHDK_01613 1.49e-273 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KHLDIHDK_01614 6.59e-44 - - - - - - - -
KHLDIHDK_01615 1.3e-238 senX3 2.7.13.3 - T ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
KHLDIHDK_01616 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
KHLDIHDK_01617 1.59e-177 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHLDIHDK_01618 2.77e-222 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
KHLDIHDK_01619 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KHLDIHDK_01621 1.02e-280 - - - EGP ko:K08156,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
KHLDIHDK_01622 0.0 - - - S - - - Domain of unknown function (DUF4037)
KHLDIHDK_01623 2.52e-149 - - - S - - - Protein of unknown function (DUF4125)
KHLDIHDK_01624 0.0 - - - S ko:K06889 - ko00000 alpha beta
KHLDIHDK_01625 8.57e-107 - - - - - - - -
KHLDIHDK_01626 0.0 pspC - - KT - - - PspC domain
KHLDIHDK_01627 2.84e-301 tcsS3 - - KT - - - PspC domain
KHLDIHDK_01628 1.01e-152 tcsR3 - - K - - - helix_turn_helix, Lux Regulon
KHLDIHDK_01629 4.59e-226 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KHLDIHDK_01630 1.63e-259 - 2.7.1.162 - S ko:K13059 - ko00000,ko01000 Phosphotransferase enzyme family
KHLDIHDK_01631 0.0 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
KHLDIHDK_01632 5.76e-217 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
KHLDIHDK_01633 3.93e-223 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01634 2.85e-316 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_01636 5.59e-308 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHLDIHDK_01637 4.81e-257 - - - I - - - Diacylglycerol kinase catalytic domain
KHLDIHDK_01638 4.54e-209 arbG - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
KHLDIHDK_01639 0.0 ptsG - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system, glucose-specific IIABC component
KHLDIHDK_01640 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
KHLDIHDK_01641 2.3e-254 - - - S - - - Protein conserved in bacteria
KHLDIHDK_01642 1.23e-96 - - - K - - - Transcriptional regulator
KHLDIHDK_01643 0.0 merA 1.16.1.1 - C ko:K00520,ko:K21739 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHLDIHDK_01644 7.46e-240 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHLDIHDK_01645 4.47e-163 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KHLDIHDK_01646 5.05e-07 - - - S - - - Mitochondrial domain of unknown function (DUF1713)
KHLDIHDK_01647 4.12e-133 - - - - - - - -
KHLDIHDK_01648 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KHLDIHDK_01649 8.69e-280 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin kinase
KHLDIHDK_01650 3.09e-274 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KHLDIHDK_01651 3.5e-107 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KHLDIHDK_01652 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KHLDIHDK_01653 1.3e-242 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KHLDIHDK_01654 9.65e-163 - - - - - - - -
KHLDIHDK_01655 1.2e-124 - - - K - - - helix_turn _helix lactose operon repressor
KHLDIHDK_01657 1.25e-195 - - - E - - - Transglutaminase/protease-like homologues
KHLDIHDK_01658 0.0 gcs2 - - S ko:K06048 - ko00000,ko01000 A circularly permuted ATPgrasp
KHLDIHDK_01659 1.27e-218 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KHLDIHDK_01660 2.44e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
KHLDIHDK_01661 8.1e-236 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHLDIHDK_01662 7.34e-86 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KHLDIHDK_01663 2e-82 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KHLDIHDK_01664 1.47e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
KHLDIHDK_01665 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHLDIHDK_01666 2.57e-128 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KHLDIHDK_01667 4.67e-316 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KHLDIHDK_01668 1.07e-98 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KHLDIHDK_01669 3.26e-36 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30p/L7e
KHLDIHDK_01670 2.25e-129 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KHLDIHDK_01671 3.09e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KHLDIHDK_01672 1.33e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KHLDIHDK_01673 3.17e-90 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KHLDIHDK_01674 7.06e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHLDIHDK_01675 1.95e-134 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHLDIHDK_01676 5.4e-69 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KHLDIHDK_01677 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KHLDIHDK_01678 1.11e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KHLDIHDK_01679 1.97e-49 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KHLDIHDK_01680 3.85e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KHLDIHDK_01681 1.85e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KHLDIHDK_01682 1.09e-74 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KHLDIHDK_01683 1.4e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHLDIHDK_01684 3.85e-195 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHLDIHDK_01685 2.54e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KHLDIHDK_01686 9.78e-151 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
KHLDIHDK_01687 1.11e-149 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KHLDIHDK_01688 9.35e-68 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KHLDIHDK_01689 3.82e-176 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
KHLDIHDK_01690 1.53e-186 - - - S - - - YwiC-like protein
KHLDIHDK_01691 0.0 adhE 1.1.1.1, 1.2.1.10, 1.2.1.81 - C ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
KHLDIHDK_01692 1.08e-216 - - - K - - - helix_turn_helix, arabinose operon control protein
KHLDIHDK_01693 6.77e-247 - 1.1.1.9 - C ko:K05351 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
KHLDIHDK_01694 1.73e-248 csbX - - EGP - - - Major Facilitator Superfamily
KHLDIHDK_01695 1.98e-274 - - - GK - - - transcriptional repressor of nag (N-acetylglucosamine) operon K02565
KHLDIHDK_01696 2.66e-97 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KHLDIHDK_01697 3.04e-296 csbX - - EGP - - - Major Facilitator Superfamily
KHLDIHDK_01698 2.47e-227 - 1.1.1.1, 1.1.1.287, 1.6.5.5 - C ko:K00001,ko:K00344,ko:K17818 ko00010,ko00040,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
KHLDIHDK_01699 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
KHLDIHDK_01700 9.6e-106 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KHLDIHDK_01701 5.33e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KHLDIHDK_01702 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
KHLDIHDK_01703 9.47e-152 - - - - - - - -
KHLDIHDK_01704 6.88e-144 yigZ - - S - - - Uncharacterized protein family UPF0029
KHLDIHDK_01705 5.18e-237 pdxB - - EH - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHLDIHDK_01706 1.04e-147 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein PGA_cap
KHLDIHDK_01707 1.16e-311 - 3.2.1.21 - G ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
KHLDIHDK_01708 5.08e-205 - - - U ko:K02026,ko:K10190 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01709 2.42e-208 - - - U ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01710 1.33e-312 - - - G ko:K02027,ko:K10227 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_01711 7.41e-277 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHLDIHDK_01712 2.08e-30 - - - - - - - -
KHLDIHDK_01714 2.95e-79 - - - S ko:K11939 - ko00000,ko02000 EamA-like transporter family
KHLDIHDK_01715 1.68e-257 - - - L ko:K07496 - ko00000 Helix-turn-helix domain
KHLDIHDK_01716 6.73e-133 - - - L ko:K07450 - ko00000 Resolvase, N terminal domain
KHLDIHDK_01717 5.66e-28 - - - S ko:K11939 - ko00000,ko02000 EamA-like transporter family
KHLDIHDK_01718 2.57e-304 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHLDIHDK_01719 3.6e-285 dapC - - E - - - Aminotransferase class I and II
KHLDIHDK_01720 4.51e-79 fdxA - - C ko:K05524 - ko00000 4Fe-4S binding domain
KHLDIHDK_01721 0.0 - - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
KHLDIHDK_01722 4.07e-288 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
KHLDIHDK_01723 1.03e-34 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
KHLDIHDK_01727 1.73e-63 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHLDIHDK_01728 1.38e-185 - - - - - - - -
KHLDIHDK_01729 1.22e-149 rimJ 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KHLDIHDK_01730 2.02e-76 ygfA 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 5-formyltetrahydrofolate cyclo-ligase family
KHLDIHDK_01731 6.24e-43 - - - S - - - Putative regulatory protein
KHLDIHDK_01732 2.79e-137 - - - NO - - - SAF
KHLDIHDK_01733 8.07e-34 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
KHLDIHDK_01734 0.0 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
KHLDIHDK_01735 4.22e-281 - - - T - - - Forkhead associated domain
KHLDIHDK_01736 1.06e-73 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KHLDIHDK_01737 2.41e-113 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KHLDIHDK_01738 8.38e-188 - - - S - - - alpha beta
KHLDIHDK_01739 0.0 - - - S ko:K06901 - ko00000,ko02000 Permease family
KHLDIHDK_01740 4.51e-190 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KHLDIHDK_01741 1.86e-221 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
KHLDIHDK_01742 6.67e-212 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KHLDIHDK_01743 2.32e-260 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import
KHLDIHDK_01744 1.5e-182 regX3 - - KT ko:K07776 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
KHLDIHDK_01745 1.15e-281 phoR 2.7.13.3 - T ko:K07636,ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
KHLDIHDK_01746 1.95e-307 - - - EGP - - - Sugar (and other) transporter
KHLDIHDK_01747 1.48e-159 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KHLDIHDK_01748 9.45e-300 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KHLDIHDK_01749 9.77e-279 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KHLDIHDK_01750 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
KHLDIHDK_01751 2.77e-119 - - - D - - - nuclear chromosome segregation
KHLDIHDK_01752 5.05e-161 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KHLDIHDK_01753 1.33e-193 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KHLDIHDK_01754 5.22e-255 yfiH - - Q ko:K05810 - ko00000,ko01000 Multi-copper polyphenol oxidoreductase laccase
KHLDIHDK_01755 0.0 - - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase family U32 C-terminal domain
KHLDIHDK_01756 4.12e-226 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KHLDIHDK_01757 4.75e-132 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Conserved hypothetical protein 95
KHLDIHDK_01758 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 helicase superfamily c-terminal domain
KHLDIHDK_01759 1.05e-40 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
KHLDIHDK_01760 2.28e-250 - - - G - - - pfkB family carbohydrate kinase
KHLDIHDK_01761 5.57e-306 - - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
KHLDIHDK_01762 3.11e-166 - - - K - - - helix_turn_helix, mercury resistance
KHLDIHDK_01763 7.25e-82 - - - T - - - Toxic component of a toxin-antitoxin (TA) module
KHLDIHDK_01764 2.94e-71 - - - L - - - RelB antitoxin
KHLDIHDK_01765 1.18e-34 yxiO - - G ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Major facilitator Superfamily
KHLDIHDK_01766 1.72e-245 - - - K - - - Helix-turn-helix XRE-family like proteins
KHLDIHDK_01767 8.42e-30 - - - - - - - -
KHLDIHDK_01768 9.85e-147 - - - S - - - Alpha/beta hydrolase family
KHLDIHDK_01772 6.21e-22 - - - EGP - - - Transporter major facilitator family protein
KHLDIHDK_01773 1.08e-30 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
KHLDIHDK_01774 0.0 fas - - I ko:K11533 ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931 ko00000,ko00001,ko00002,ko01000,ko01004 Beta-ketoacyl synthase, C-terminal domain
KHLDIHDK_01775 0.0 pccB - - I - - - Carboxyl transferase domain
KHLDIHDK_01776 0.0 accC 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase L chain, ATP binding domain protein
KHLDIHDK_01777 1.31e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
KHLDIHDK_01778 5.5e-207 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
KHLDIHDK_01779 0.0 - - - - - - - -
KHLDIHDK_01780 3.74e-211 - - - QT - - - PucR C-terminal helix-turn-helix domain
KHLDIHDK_01781 1.75e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KHLDIHDK_01782 5e-96 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHLDIHDK_01783 3.98e-187 - - - K - - - Psort location Cytoplasmic, score
KHLDIHDK_01784 1.43e-169 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KHLDIHDK_01785 3.36e-42 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KHLDIHDK_01787 6.81e-293 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
KHLDIHDK_01788 1.85e-302 - - - G - - - polysaccharide deacetylase
KHLDIHDK_01789 1.93e-252 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KHLDIHDK_01790 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KHLDIHDK_01791 1.44e-51 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L27 protein
KHLDIHDK_01792 1.01e-62 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
KHLDIHDK_01793 0.0 rne 3.1.26.12 - J ko:K08300,ko:K08301 ko03018,map03018 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Ribonuclease E/G family
KHLDIHDK_01794 6.01e-294 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
KHLDIHDK_01795 1.58e-213 - - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
KHLDIHDK_01796 6.01e-214 - 4.1.2.28 - EM ko:K22397 ko00040,map00040 ko00000,ko00001,ko01000 Dihydrodipicolinate synthetase family
KHLDIHDK_01797 1.15e-190 - - - S ko:K07046 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Amidohydrolase
KHLDIHDK_01798 9.55e-271 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
KHLDIHDK_01799 5.27e-191 - 1.1.1.100, 1.1.1.413 - IQ ko:K00059,ko:K18333,ko:K22322 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
KHLDIHDK_01800 0.0 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Enolase C-terminal domain-like
KHLDIHDK_01801 2.36e-245 - - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
KHLDIHDK_01802 0.0 - - - V - - - Efflux ABC transporter, permease protein
KHLDIHDK_01803 8.7e-178 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_01804 3.47e-38 - - - S - - - Protein of unknown function (DUF1778)
KHLDIHDK_01805 4.05e-119 - - - K - - - Acetyltransferase (GNAT) family
KHLDIHDK_01806 0.0 maf - - DF ko:K06287 - ko00000 Maf-like protein
KHLDIHDK_01807 1.25e-261 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KHLDIHDK_01808 1.59e-303 hom 1.1.1.3, 2.7.2.4 - E ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
KHLDIHDK_01809 1.44e-65 nagE 2.7.1.193 - G ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
KHLDIHDK_01810 3.11e-72 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KHLDIHDK_01811 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KHLDIHDK_01812 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
KHLDIHDK_01813 4.49e-169 - - - K - - - Bacterial regulatory proteins, tetR family
KHLDIHDK_01814 1.63e-281 - - - G - - - Transmembrane secretion effector
KHLDIHDK_01815 0.0 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHLDIHDK_01816 0.0 nox - - C - - - Pyridine nucleotide-disulphide oxidoreductase
KHLDIHDK_01817 4.34e-200 - - - ET ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KHLDIHDK_01818 3.01e-155 - - - P ko:K16958 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01819 3.8e-179 - - - P ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01820 1.05e-135 - - - S - - - L-2-amino-thiazoline-4-carboxylic acid hydrolase
KHLDIHDK_01821 9.29e-169 - - - E ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_01822 1.77e-281 pyr 1.3.98.1 - F ko:K00226 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroorotate dehydrogenase
KHLDIHDK_01823 4.32e-25 - - - T - - - Histidine kinase
KHLDIHDK_01824 3.22e-17 - - - S ko:K08981 - ko00000 Bacterial PH domain
KHLDIHDK_01825 6.62e-171 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KHLDIHDK_01826 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KHLDIHDK_01827 5.58e-180 ltbR - - K - - - Transcriptional regulator, IclR family, C-terminal domain protein
KHLDIHDK_01828 0.0 - - - S - - - Calcineurin-like phosphoesterase
KHLDIHDK_01829 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KHLDIHDK_01830 0.0 mutT 3.6.1.55 - LT ko:K03574 - ko00000,ko01000,ko03400 Phosphoglycerate mutase family
KHLDIHDK_01831 1.47e-177 - - - - - - - -
KHLDIHDK_01832 0.0 - - - G - - - N-terminal domain of (some) glycogen debranching enzymes
KHLDIHDK_01833 2.11e-178 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01834 1.3e-267 - - - U ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01835 5.61e-263 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_01836 2.81e-163 - - - K - - - helix_turn _helix lactose operon repressor
KHLDIHDK_01837 9.47e-151 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHLDIHDK_01838 1.05e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHLDIHDK_01839 1.27e-274 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
KHLDIHDK_01840 5e-279 gluQ 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KHLDIHDK_01842 0.0 clpB - - O ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KHLDIHDK_01843 2.32e-208 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
KHLDIHDK_01844 2.43e-201 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
KHLDIHDK_01845 1.8e-162 - - - S - - - Domain of unknown function (DUF4190)
KHLDIHDK_01846 4.37e-219 - - - - - - - -
KHLDIHDK_01847 3.99e-298 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
KHLDIHDK_01848 2.23e-82 - - - K - - - Helix-turn-helix domain
KHLDIHDK_01849 1.9e-08 - - - S - - - PIN domain
KHLDIHDK_01850 3.78e-168 - - - L - - - PFAM Integrase catalytic
KHLDIHDK_01851 9.88e-57 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 sugar phosphate isomerase involved in capsule formation
KHLDIHDK_01852 1.41e-72 - - - G - - - Branched-chain amino acid transport system / permease component
KHLDIHDK_01853 9.99e-96 - - - P - - - branched-chain amino acid ABC transporter, permease protein
KHLDIHDK_01854 8.91e-145 - - - G - - - ATPases associated with a variety of cellular activities
KHLDIHDK_01855 3.96e-100 - - - G - - - ABC-type sugar transport system periplasmic component
KHLDIHDK_01856 7.81e-211 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
KHLDIHDK_01857 4.05e-90 xylR - - GK - - - ROK family
KHLDIHDK_01858 1.5e-47 - - - - - - - -
KHLDIHDK_01859 1.01e-256 - - - M - - - Glycosyltransferase like family 2
KHLDIHDK_01860 7.54e-229 - - - S - - - Predicted membrane protein (DUF2142)
KHLDIHDK_01861 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
KHLDIHDK_01862 0.0 - - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferase family 2
KHLDIHDK_01863 2.23e-206 - - - GM ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHLDIHDK_01864 1.16e-152 tagG - - U ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
KHLDIHDK_01865 1.53e-214 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KHLDIHDK_01866 0.0 rfbD 1.1.1.133, 5.1.3.13 - M ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KHLDIHDK_01867 1.69e-262 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KHLDIHDK_01868 0.0 - - - - - - - -
KHLDIHDK_01869 8.22e-213 - - - M - - - Glycosyl transferase family 2
KHLDIHDK_01870 3.74e-39 - - - M - - - nuclease
KHLDIHDK_01871 7.76e-99 - - - M - - - L,D-transpeptidase catalytic domain
KHLDIHDK_01872 1.94e-232 - - - M - - - Glycosyl hydrolases family 25
KHLDIHDK_01873 2.44e-304 yvhJ - - K - - - Cell envelope-related transcriptional attenuator domain
KHLDIHDK_01874 0.0 - - - V - - - ABC transporter permease
KHLDIHDK_01875 1.32e-243 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KHLDIHDK_01876 6.38e-183 - - - T ko:K06950 - ko00000 HD domain
KHLDIHDK_01877 2.46e-205 - - - S - - - Glutamine amidotransferase domain
KHLDIHDK_01878 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
KHLDIHDK_01879 6.68e-238 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
KHLDIHDK_01880 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
KHLDIHDK_01881 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
KHLDIHDK_01882 5.54e-29 - - - S ko:K06921 - ko00000 ATPase domain predominantly from Archaea
KHLDIHDK_01883 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
KHLDIHDK_01884 2.82e-53 - - - G - - - Glycosyl hydrolases family 43
KHLDIHDK_01885 6.69e-86 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
KHLDIHDK_01886 8.76e-81 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
KHLDIHDK_01887 3.2e-106 - 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
KHLDIHDK_01888 2.02e-62 - - - - - - - -
KHLDIHDK_01889 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHLDIHDK_01890 1.78e-154 - - - - - - - -
KHLDIHDK_01891 2.61e-236 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHLDIHDK_01893 0.0 - - - G - - - MFS/sugar transport protein
KHLDIHDK_01894 6.39e-233 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KHLDIHDK_01895 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
KHLDIHDK_01896 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
KHLDIHDK_01897 1.11e-118 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KHLDIHDK_01898 0.0 - - - E ko:K03293 - ko00000 Amino acid permease
KHLDIHDK_01899 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KHLDIHDK_01900 1.76e-165 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KHLDIHDK_01901 0.0 aroP - - E ko:K03293,ko:K11732 - ko00000,ko02000 aromatic amino acid transport protein AroP K03293
KHLDIHDK_01902 8.13e-137 - - - S - - - Protein of unknown function, DUF624
KHLDIHDK_01903 4.49e-196 - - - G ko:K02026,ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHLDIHDK_01904 3.3e-200 msmF - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01905 9.83e-236 - - - K - - - Psort location Cytoplasmic, score
KHLDIHDK_01906 0.0 amyE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_01907 1.29e-132 gpm2 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
KHLDIHDK_01908 3.72e-78 - - - S - - - Protein of unknown function (DUF4235)
KHLDIHDK_01909 1.14e-181 nfrA - - C - - - Nitroreductase family
KHLDIHDK_01910 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
KHLDIHDK_01911 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
KHLDIHDK_01912 6.32e-55 - - - - - - - -
KHLDIHDK_01916 1.02e-182 cobB2 - - K ko:K12410 - ko00000,ko01000 Sir2 family
KHLDIHDK_01917 1.38e-293 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
KHLDIHDK_01918 0.0 - 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
KHLDIHDK_01919 7.15e-197 - - - G ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01920 4.48e-207 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHLDIHDK_01921 9.35e-312 - - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHLDIHDK_01922 6.32e-294 - - - GK - - - ROK family
KHLDIHDK_01923 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
KHLDIHDK_01924 6.16e-103 tadA 3.5.4.1, 3.5.4.33 - FJ ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KHLDIHDK_01925 0.0 nhaP - - P ko:K03316 - ko00000 Sodium/hydrogen exchanger family
KHLDIHDK_01926 3.06e-160 - - - S ko:K07090 - ko00000 membrane transporter protein
KHLDIHDK_01927 5.07e-188 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
KHLDIHDK_01928 5.44e-197 - - - - - - - -
KHLDIHDK_01929 6.04e-144 dcd 3.5.4.13 - F ko:K01494 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dCTP deaminase family
KHLDIHDK_01930 2.96e-130 - - - - - - - -
KHLDIHDK_01931 0.0 pacL2 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
KHLDIHDK_01932 1.55e-20 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHLDIHDK_01933 1.58e-112 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KHLDIHDK_01934 0.0 nagE 2.7.1.193 - G ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
KHLDIHDK_01935 7.62e-271 - - - EGP - - - Transmembrane secretion effector
KHLDIHDK_01936 2.26e-222 rlmB 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHLDIHDK_01937 6.27e-215 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
KHLDIHDK_01938 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KHLDIHDK_01939 0.0 - - - KLT - - - Domain of unknown function (DUF4032)
KHLDIHDK_01940 7.78e-200 - - - - - - - -
KHLDIHDK_01941 7.31e-22 tnp3521a2 - - L - - - Integrase core domain
KHLDIHDK_01942 7.94e-167 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHLDIHDK_01943 6.91e-187 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
KHLDIHDK_01944 4.51e-222 rbsA 3.6.3.17 - G ko:K10441,ko:K10542,ko:K17215 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KHLDIHDK_01945 6.14e-191 - - - U ko:K10439,ko:K10440 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
KHLDIHDK_01946 3.33e-232 - - - - - - - -
KHLDIHDK_01947 3.62e-180 - - - L - - - Winged helix-turn helix
KHLDIHDK_01948 4.11e-68 - - - S - - - LPXTG-motif cell wall anchor domain protein
KHLDIHDK_01949 7.62e-270 ugpC - - E ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KHLDIHDK_01950 2.33e-97 - - - K ko:K03710 - ko00000,ko03000 UTRA domain
KHLDIHDK_01951 1.55e-307 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
KHLDIHDK_01952 3.61e-61 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KHLDIHDK_01953 1.66e-95 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHLDIHDK_01954 1.91e-280 - - - M - - - Glycosyltransferase like family 2
KHLDIHDK_01955 2.58e-182 - - - K - - - LytTr DNA-binding domain
KHLDIHDK_01956 3.28e-313 - - - T - - - GHKL domain
KHLDIHDK_01957 1.26e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHLDIHDK_01959 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHLDIHDK_01960 2.98e-115 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
KHLDIHDK_01961 1.9e-56 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
KHLDIHDK_01962 3.72e-159 - - - S - - - Psort location CytoplasmicMembrane, score
KHLDIHDK_01963 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
KHLDIHDK_01964 2.24e-155 - - - K - - - Helix-turn-helix XRE-family like proteins
KHLDIHDK_01965 2.5e-162 - - - S - - - Protein of unknown function (DUF3990)
KHLDIHDK_01966 1.55e-99 - - - U ko:K10716 - ko00000,ko02000 Ion channel
KHLDIHDK_01967 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
KHLDIHDK_01968 0.0 - - - KLT - - - Protein tyrosine kinase
KHLDIHDK_01969 4.61e-184 - - - O - - - Thioredoxin
KHLDIHDK_01971 1.14e-284 rpfB - - S ko:K21688 - ko00000 G5
KHLDIHDK_01972 9.6e-217 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KHLDIHDK_01973 1.33e-226 ispE 2.7.1.148 - F ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KHLDIHDK_01974 7.2e-144 - - - S - - - LytR cell envelope-related transcriptional attenuator
KHLDIHDK_01975 0.0 pcnA 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Probable RNA and SrmB- binding site of polymerase A
KHLDIHDK_01976 7.29e-219 mutT4 - - L - - - Belongs to the Nudix hydrolase family
KHLDIHDK_01977 0.0 - - - - - - - -
KHLDIHDK_01978 0.0 mviN - - KLT ko:K03980 - ko00000,ko01011,ko02000 MviN-like protein
KHLDIHDK_01979 1.04e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KHLDIHDK_01980 5.76e-286 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KHLDIHDK_01981 2.2e-224 parA - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
KHLDIHDK_01982 3.05e-160 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
KHLDIHDK_01983 1.14e-118 jag - - S ko:K06346 - ko00000 Putative single-stranded nucleic acids-binding domain
KHLDIHDK_01984 1.07e-238 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
KHLDIHDK_01985 2.07e-73 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KHLDIHDK_01986 4.62e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)