ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KOOLEIAC_00001 5.62e-184 - - - S ko:K07043 - ko00000 Protein of unknown function DUF45
KOOLEIAC_00002 2.53e-54 gntK 2.7.1.12, 2.7.1.71 - F ko:K00851,ko:K00891 ko00030,ko00400,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00400,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate kinase
KOOLEIAC_00003 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
KOOLEIAC_00004 1.55e-109 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KOOLEIAC_00005 4e-297 - - - P ko:K03699 - ko00000,ko02042 Transporter associated domain
KOOLEIAC_00006 1.53e-266 - - - S - - - AAA ATPase domain
KOOLEIAC_00007 2.89e-152 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
KOOLEIAC_00008 6.83e-138 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
KOOLEIAC_00009 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
KOOLEIAC_00010 0.0 - 5.1.3.2 - GM ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 ADP-glyceromanno-heptose 6-epimerase activity
KOOLEIAC_00011 1.51e-206 - - - - - - - -
KOOLEIAC_00012 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2194)
KOOLEIAC_00013 0.0 - - GT4 M ko:K21011 ko02025,map02025 ko00000,ko00001,ko01003 Domain of unknown function (DUF3492)
KOOLEIAC_00014 0.0 - - - S ko:K21012 ko02025,map02025 ko00000,ko00001 Putative exopolysaccharide Exporter (EPS-E)
KOOLEIAC_00015 0.0 - - - M ko:K06330 - ko00000 CotH kinase protein
KOOLEIAC_00016 2.25e-202 - - - P - - - VTC domain
KOOLEIAC_00017 1.72e-142 - - - S - - - Domain of unknown function (DUF4956)
KOOLEIAC_00018 0.0 - 3.1.4.52 - T ko:K14051 ko02024,ko02026,map02024,map02026 ko00000,ko00001,ko01000 Putative diguanylate phosphodiesterase
KOOLEIAC_00019 1.23e-159 - - - S ko:K07133 - ko00000 AAA domain
KOOLEIAC_00020 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
KOOLEIAC_00021 3.9e-08 - - - S ko:K07133 - ko00000 AAA domain
KOOLEIAC_00022 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KOOLEIAC_00023 0.0 - - - S - - - Threonine/Serine exporter, ThrE
KOOLEIAC_00024 0.0 - - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KOOLEIAC_00025 3.07e-239 - - - S - - - Protein conserved in bacteria
KOOLEIAC_00026 0.0 - - - S - - - Amidohydrolase family
KOOLEIAC_00027 4.87e-260 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KOOLEIAC_00028 2.09e-60 - - - S - - - Protein of unknown function (DUF3073)
KOOLEIAC_00029 7.32e-144 - - - K - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KOOLEIAC_00030 9.19e-266 - - - T - - - Histidine kinase
KOOLEIAC_00031 8.23e-294 - - - EGP - - - Major Facilitator Superfamily
KOOLEIAC_00032 1.75e-93 - - - I - - - Sterol carrier protein
KOOLEIAC_00033 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KOOLEIAC_00034 7.56e-48 - - - - - - - -
KOOLEIAC_00035 2.52e-180 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
KOOLEIAC_00036 2.41e-101 crgA - - D - - - Involved in cell division
KOOLEIAC_00037 1.56e-162 - - - S - - - Bacterial protein of unknown function (DUF881)
KOOLEIAC_00038 1.32e-290 srtB 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
KOOLEIAC_00039 7.81e-155 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 para-aminobenzoate synthase glutamine amidotransferase component II
KOOLEIAC_00040 0.0 pknB 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
KOOLEIAC_00041 1.32e-222 pknA 2.7.11.1 - T ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
KOOLEIAC_00042 0.0 pbpA - - M ko:K05364 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
KOOLEIAC_00043 0.0 rodA - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KOOLEIAC_00044 0.0 pstP 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Sigma factor PP2C-like phosphatases
KOOLEIAC_00045 1.09e-105 fhaB - - T - - - Inner membrane component of T3SS, cytoplasmic domain
KOOLEIAC_00046 3.54e-165 fhaA - - T - - - Protein of unknown function (DUF2662)
KOOLEIAC_00047 0.0 pepX 3.4.14.5 - E ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Dipeptidyl peptidase IV (DPP IV) N-terminal region
KOOLEIAC_00048 2.76e-273 pldB 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Serine aminopeptidase, S33
KOOLEIAC_00049 4.23e-120 - - - O - - - Hsp20/alpha crystallin family
KOOLEIAC_00050 8.01e-229 - - - EG - - - EamA-like transporter family
KOOLEIAC_00051 1.09e-29 - - - - - - - -
KOOLEIAC_00052 0.0 - - - S - - - Putative esterase
KOOLEIAC_00053 0.0 lysX - - S - - - Uncharacterised conserved protein (DUF2156)
KOOLEIAC_00054 4.46e-257 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KOOLEIAC_00055 5.02e-169 - - - S ko:K07005 - ko00000 Pyridoxamine 5'-phosphate oxidase
KOOLEIAC_00056 1.38e-254 - - - S - - - Fic/DOC family
KOOLEIAC_00057 1.94e-55 - - - M - - - Glycosyltransferase like family 2
KOOLEIAC_00058 5.47e-141 - - - M - - - Glycosyltransferase like family 2
KOOLEIAC_00059 0.0 - - - KL - - - Domain of unknown function (DUF3427)
KOOLEIAC_00060 1.64e-98 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
KOOLEIAC_00061 8.66e-70 - - - S - - - Putative heavy-metal-binding
KOOLEIAC_00062 6.79e-189 - - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
KOOLEIAC_00064 0.0 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KOOLEIAC_00065 0.0 degP - - O ko:K08372 ko02020,map02020 ko00000,ko00001,ko01000,ko01002 Domain present in PSD-95, Dlg, and ZO-1/2.
KOOLEIAC_00066 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
KOOLEIAC_00067 0.0 fprA 1.18.1.2, 1.19.1.1 - C ko:K00528 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase
KOOLEIAC_00068 3e-222 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KOOLEIAC_00070 1.55e-223 - - - EG - - - EamA-like transporter family
KOOLEIAC_00071 2.87e-248 fbaA 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
KOOLEIAC_00072 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KOOLEIAC_00073 0.0 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
KOOLEIAC_00074 2.69e-209 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KOOLEIAC_00075 5.18e-81 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KOOLEIAC_00076 7.25e-64 livK - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
KOOLEIAC_00077 8.76e-260 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KOOLEIAC_00079 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Domain of unknown function (DUF1964)
KOOLEIAC_00080 0.0 scrT - - G - - - Transporter major facilitator family protein
KOOLEIAC_00081 2e-241 - - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KOOLEIAC_00082 0.0 - - - EGP - - - Sugar (and other) transporter
KOOLEIAC_00083 6.32e-55 - - - - - - - -
KOOLEIAC_00084 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
KOOLEIAC_00085 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
KOOLEIAC_00086 1.14e-181 nfrA - - C - - - Nitroreductase family
KOOLEIAC_00087 6.43e-79 - - - S - - - Protein of unknown function (DUF4235)
KOOLEIAC_00088 1.29e-132 gpm2 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
KOOLEIAC_00089 0.0 amyE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_00090 9.83e-236 - - - K - - - Psort location Cytoplasmic, score
KOOLEIAC_00091 3.3e-200 msmF - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_00092 4.49e-196 - - - G ko:K02026,ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KOOLEIAC_00093 8.13e-137 - - - S - - - Protein of unknown function, DUF624
KOOLEIAC_00094 0.0 aroP - - E ko:K03293,ko:K11732 - ko00000,ko02000 aromatic amino acid transport protein AroP K03293
KOOLEIAC_00095 1.76e-165 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KOOLEIAC_00096 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KOOLEIAC_00098 2.78e-17 - - - G - - - Acyltransferase family
KOOLEIAC_00100 3.33e-67 - - - S - - - enterobacterial common antigen metabolic process
KOOLEIAC_00101 3.91e-217 - - - L - - - Transposase and inactivated derivatives IS30 family
KOOLEIAC_00102 1.99e-301 - - - L - - - Transposase
KOOLEIAC_00103 2.31e-209 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Enolase C-terminal domain-like
KOOLEIAC_00104 9.38e-185 - 1.1.1.100, 1.1.1.413 - IQ ko:K00059,ko:K18333,ko:K22322 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
KOOLEIAC_00105 2.1e-214 - 4.1.2.28 - EM ko:K22397 ko00040,map00040 ko00000,ko00001,ko01000 Dihydrodipicolinate synthetase family
KOOLEIAC_00106 0.0 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65, N-terminal domain
KOOLEIAC_00107 3.87e-199 - - - S - - - Aldo/keto reductase family
KOOLEIAC_00108 1.7e-70 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Acylphosphatase
KOOLEIAC_00109 0.0 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KOOLEIAC_00110 3.03e-277 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KOOLEIAC_00111 1.66e-144 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Imidazoleglycerol-phosphate dehydratase
KOOLEIAC_00112 4.38e-162 - - - - - - - -
KOOLEIAC_00113 2.07e-155 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KOOLEIAC_00114 7.13e-169 hisA 5.3.1.16, 5.3.1.24 - E ko:K01814,ko:K01817 ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis protein
KOOLEIAC_00115 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2252)
KOOLEIAC_00116 0.0 glnA2 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KOOLEIAC_00117 7.18e-279 - - - EGP ko:K18567,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
KOOLEIAC_00118 0.0 hrpA 3.6.4.13 - L ko:K03578 - ko00000,ko01000 Helicase associated domain (HA2) Add an annotation
KOOLEIAC_00119 1.99e-159 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase (PrmA)
KOOLEIAC_00120 0.0 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KOOLEIAC_00121 1.61e-225 ldh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KOOLEIAC_00122 1.39e-207 czcD - - P ko:K16264 - ko00000,ko02000 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KOOLEIAC_00123 2.49e-167 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KOOLEIAC_00124 5e-68 - - - M - - - Lysin motif
KOOLEIAC_00125 4.08e-101 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KOOLEIAC_00126 2.65e-289 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
KOOLEIAC_00127 0.0 - - - L - - - DNA helicase
KOOLEIAC_00128 2.33e-120 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
KOOLEIAC_00129 2e-241 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KOOLEIAC_00130 9.1e-91 - - - D - - - Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KOOLEIAC_00131 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding protein, transpeptidase domain protein
KOOLEIAC_00132 2.6e-200 - - - M - - - Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KOOLEIAC_00133 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KOOLEIAC_00134 9.54e-265 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KOOLEIAC_00135 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KOOLEIAC_00136 2.45e-288 ftsW 2.4.1.227 GT28 D ko:K02563,ko:K03588 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011,ko02000,ko03036 Belongs to the SEDS family
KOOLEIAC_00137 1.24e-278 murG 2.4.1.227, 6.3.2.8 GT28 M ko:K01924,ko:K02563 ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KOOLEIAC_00138 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KOOLEIAC_00139 5.6e-229 ftsQ - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein FtsQ
KOOLEIAC_00141 1.74e-112 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KOOLEIAC_00142 9.92e-96 - - - G - - - Major Facilitator Superfamily
KOOLEIAC_00143 9.24e-49 - - - G - - - Major Facilitator Superfamily
KOOLEIAC_00144 1.12e-214 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
KOOLEIAC_00145 7.27e-285 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KOOLEIAC_00146 1.16e-210 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KOOLEIAC_00147 2.75e-267 - - - GK - - - ROK family
KOOLEIAC_00148 9.44e-193 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KOOLEIAC_00149 5.02e-314 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
KOOLEIAC_00150 1.58e-127 - - - F - - - NUDIX domain
KOOLEIAC_00151 0.0 pepP 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Aminopeptidase P, N-terminal domain
KOOLEIAC_00152 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Mur ligase middle domain
KOOLEIAC_00153 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KOOLEIAC_00154 4.74e-106 - - - V - - - Acetyltransferase (GNAT) domain
KOOLEIAC_00155 3.91e-245 - - - V - - - Acetyltransferase (GNAT) domain
KOOLEIAC_00156 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KOOLEIAC_00157 1.11e-176 sigH - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
KOOLEIAC_00158 3.96e-69 - - - - - - - -
KOOLEIAC_00159 1.92e-239 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KOOLEIAC_00160 2.44e-244 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KOOLEIAC_00161 5.06e-234 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KOOLEIAC_00162 4.92e-115 ybaK - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KOOLEIAC_00163 1.23e-252 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KOOLEIAC_00164 5.45e-173 - 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiamin pyrophosphokinase, vitamin B1 binding domain
KOOLEIAC_00165 9.7e-51 - - - S - - - Spermine/spermidine synthase domain
KOOLEIAC_00166 1.3e-30 - - - S - - - Spermine/spermidine synthase domain
KOOLEIAC_00167 4.69e-155 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KOOLEIAC_00168 2.72e-34 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L35
KOOLEIAC_00169 7.76e-81 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KOOLEIAC_00170 7.67e-114 - - - KT ko:K02647 - ko00000,ko03000 Putative sugar diacid recognition
KOOLEIAC_00171 3.78e-206 - - - EG ko:K03299 - ko00000,ko02000 GntP family permease
KOOLEIAC_00172 1.83e-245 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
KOOLEIAC_00173 5.77e-201 xerD - - D ko:K03733,ko:K04763 - ko00000,ko03036 recombinase XerD
KOOLEIAC_00174 4.16e-194 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
KOOLEIAC_00175 2.21e-193 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KOOLEIAC_00176 2.87e-146 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KOOLEIAC_00177 2.42e-199 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX hydrolase
KOOLEIAC_00178 0.0 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KOOLEIAC_00179 0.0 nadB 1.4.3.16, 2.4.2.19 - H ko:K00278,ko:K00767 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
KOOLEIAC_00180 7.53e-208 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate phosphoribosyl transferase, N-terminal domain
KOOLEIAC_00181 1.92e-301 iscS1 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
KOOLEIAC_00182 2.12e-309 nanT - - U ko:K03290,ko:K08178,ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
KOOLEIAC_00183 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KOOLEIAC_00184 3.58e-34 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KOOLEIAC_00185 5.21e-177 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_00186 1.46e-139 - - - K - - - Virulence activator alpha C-term
KOOLEIAC_00187 0.0 typA - - T ko:K06207 - ko00000 Elongation factor G C-terminus
KOOLEIAC_00188 3.53e-102 - - - - - - - -
KOOLEIAC_00189 1.41e-241 pheA 4.2.1.51, 5.4.99.5 - E ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
KOOLEIAC_00190 4.06e-244 tyrA 1.3.1.12 - E ko:K00210,ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydrogenase
KOOLEIAC_00191 2.36e-56 - - - - - - - -
KOOLEIAC_00192 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
KOOLEIAC_00193 3.03e-189 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KOOLEIAC_00194 3.61e-243 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
KOOLEIAC_00195 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
KOOLEIAC_00196 1.39e-204 dppB - - EP ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_00197 2.81e-233 dppC - - EP ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
KOOLEIAC_00198 0.0 - - - EP ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
KOOLEIAC_00199 1.13e-217 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease/Exonuclease/phosphatase family
KOOLEIAC_00200 2.93e-197 - - - S - - - Protein of unknown function (DUF3710)
KOOLEIAC_00201 2.99e-174 - - - S - - - Protein of unknown function (DUF3159)
KOOLEIAC_00202 1.47e-303 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KOOLEIAC_00203 4.72e-128 - - - - - - - -
KOOLEIAC_00204 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
KOOLEIAC_00205 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KOOLEIAC_00206 2.33e-155 - - - E - - - Psort location Cytoplasmic, score 8.87
KOOLEIAC_00207 2.76e-107 - - - K - - - helix_turn_helix, Lux Regulon
KOOLEIAC_00208 2.83e-175 - - - S ko:K06890 - ko00000 Belongs to the BI1 family
KOOLEIAC_00209 2.83e-212 - - - EG - - - EamA-like transporter family
KOOLEIAC_00210 1.99e-192 ywaC 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
KOOLEIAC_00211 0.0 miaB 2.8.4.3 - H ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KOOLEIAC_00212 6.36e-231 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KOOLEIAC_00213 3.18e-192 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
KOOLEIAC_00214 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 FtsK SpoIIIE family protein
KOOLEIAC_00215 6.95e-152 pgsA 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KOOLEIAC_00216 7.65e-125 cinA 3.5.1.42 - S ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
KOOLEIAC_00217 2.3e-101 - - - K - - - Helix-turn-helix XRE-family like proteins
KOOLEIAC_00218 9.29e-52 - - - S - - - Protein of unknown function (DUF3046)
KOOLEIAC_00219 1.06e-260 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KOOLEIAC_00220 4.52e-133 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
KOOLEIAC_00221 1.24e-154 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KOOLEIAC_00222 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KOOLEIAC_00223 8.85e-244 trpD 2.4.2.18 - F ko:K00766 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KOOLEIAC_00224 7.98e-152 - - - - - - - -
KOOLEIAC_00225 2.4e-169 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
KOOLEIAC_00226 0.0 pknL 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 PASTA
KOOLEIAC_00227 1.67e-251 idsA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13787 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KOOLEIAC_00228 1.39e-145 - - - - - - - -
KOOLEIAC_00229 1.24e-248 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KOOLEIAC_00230 0.0 gyrB2 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
KOOLEIAC_00231 2.17e-285 - - - G - - - Major Facilitator Superfamily
KOOLEIAC_00232 7.03e-220 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KOOLEIAC_00233 0.0 lhr - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
KOOLEIAC_00237 0.0 gyrA2 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase (ATP-hydrolyzing)
KOOLEIAC_00238 4.72e-295 - - - S - - - Type I phosphodiesterase / nucleotide pyrophosphatase
KOOLEIAC_00239 6.14e-212 - - - S - - - Protein of unknown function (DUF3071)
KOOLEIAC_00240 2.02e-62 - - - S - - - Domain of unknown function (DUF4193)
KOOLEIAC_00241 5.02e-110 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KOOLEIAC_00242 0.0 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KOOLEIAC_00243 7.02e-157 ppiA 5.2.1.8 - G ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KOOLEIAC_00245 2.09e-87 - - - - - - - -
KOOLEIAC_00246 7.3e-13 - - - U - - - type IV secretory pathway VirB4
KOOLEIAC_00247 6.46e-37 - - - - - - - -
KOOLEIAC_00248 2.63e-22 - - - - - - - -
KOOLEIAC_00249 1.38e-147 - - - S - - - Helix-turn-helix domain
KOOLEIAC_00250 1.2e-82 - - - S - - - Helix-turn-helix domain
KOOLEIAC_00251 2.48e-48 - - - - - - - -
KOOLEIAC_00252 2.42e-100 - - - S - - - Transcription factor WhiB
KOOLEIAC_00253 6.29e-129 - - - D ko:K03496 - ko00000,ko03036,ko04812 AAA domain
KOOLEIAC_00254 9.63e-31 - - - - - - - -
KOOLEIAC_00257 5.33e-13 - - - M - - - cell wall anchor domain protein
KOOLEIAC_00258 1.3e-180 - - - - - - - -
KOOLEIAC_00259 2.26e-35 - - - - - - - -
KOOLEIAC_00260 1.64e-178 - - - - - - - -
KOOLEIAC_00261 2.32e-79 - - - S - - - PrgI family protein
KOOLEIAC_00262 0.0 - - - U - - - type IV secretory pathway VirB4
KOOLEIAC_00263 1.13e-202 - - - M - - - CHAP domain
KOOLEIAC_00265 2.67e-79 - - - - ko:K03646 - ko00000,ko02000 -
KOOLEIAC_00267 4.36e-123 - - - K - - - DNA binding
KOOLEIAC_00268 8.88e-128 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 D12 class N6 adenine-specific DNA methyltransferase
KOOLEIAC_00269 1.48e-15 - - - - ko:K03646 - ko00000,ko02000 -
KOOLEIAC_00271 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Type IV secretory system Conjugative DNA transfer
KOOLEIAC_00272 8.73e-48 - - - - - - - -
KOOLEIAC_00273 1.61e-43 - - - - - - - -
KOOLEIAC_00274 0.0 - - - KL - - - Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KOOLEIAC_00276 0.0 - - - - - - - -
KOOLEIAC_00277 7.22e-184 - - - S - - - Protein of unknown function (DUF3801)
KOOLEIAC_00278 0.0 - - - U - - - Relaxase/Mobilisation nuclease domain
KOOLEIAC_00279 6.14e-73 - - - S - - - Bacterial mobilisation protein (MobC)
KOOLEIAC_00280 1.01e-55 - - - K - - - Protein of unknown function (DUF2442)
KOOLEIAC_00281 5.28e-59 - - - S - - - Domain of unknown function (DUF4160)
KOOLEIAC_00284 4.51e-82 - - - - - - - -
KOOLEIAC_00285 2.49e-315 - 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase
KOOLEIAC_00286 1.73e-16 - 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase
KOOLEIAC_00287 6.61e-85 - - - - - - - -
KOOLEIAC_00288 1.77e-82 - - - - - - - -
KOOLEIAC_00289 1.63e-66 - - - - - - - -
KOOLEIAC_00290 4.48e-232 - - - S - - - Fic/DOC family
KOOLEIAC_00291 2.07e-128 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
KOOLEIAC_00293 6.23e-35 - - - - - - - -
KOOLEIAC_00294 1.76e-185 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
KOOLEIAC_00295 0.0 intA - - L - - - Phage integrase family
KOOLEIAC_00297 1.31e-98 - - - - - - - -
KOOLEIAC_00299 0.0 - - - S - - - HipA-like C-terminal domain
KOOLEIAC_00300 1.09e-220 - - - S - - - Fic/DOC family
KOOLEIAC_00301 8.29e-55 - - - - - - - -
KOOLEIAC_00302 5.12e-19 intA - - L - - - Phage integrase family
KOOLEIAC_00303 0.0 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase, middle domain
KOOLEIAC_00304 0.0 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase, middle domain
KOOLEIAC_00305 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_00306 4.03e-216 - - - G ko:K02025,ko:K17330 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_00307 5.5e-201 - - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_00308 0.0 - - - G - - - Belongs to the glycosyl hydrolase 5 (cellulase A) family
KOOLEIAC_00309 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3 C-terminal domain
KOOLEIAC_00310 8.76e-218 - - - G - - - Glycosyl hydrolase, family 20, catalytic domain
KOOLEIAC_00311 1.74e-18 - - - G - - - Glycosyl hydrolase family 85
KOOLEIAC_00312 1.26e-232 - - - G - - - Glycosyl hydrolase family 85
KOOLEIAC_00313 2.08e-161 - - - G - - - Glycosyl hydrolase family 85
KOOLEIAC_00314 1.37e-106 - - - G - - - Glycosyl hydrolase family 85
KOOLEIAC_00315 1.69e-258 - - - K - - - helix_turn _helix lactose operon repressor
KOOLEIAC_00316 6.71e-305 - - - G - - - N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KOOLEIAC_00317 0.0 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
KOOLEIAC_00318 8.47e-42 - - - - - - - -
KOOLEIAC_00319 6.15e-170 - - - C - - - Putative TM nitroreductase
KOOLEIAC_00320 1e-219 - - - EG - - - EamA-like transporter family
KOOLEIAC_00321 2.86e-93 pdxH - - S ko:K07006 - ko00000 Pfam:Pyridox_oxidase
KOOLEIAC_00322 2.85e-294 - - - L - - - ribosomal rna small subunit methyltransferase
KOOLEIAC_00323 2.1e-215 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
KOOLEIAC_00324 4.06e-217 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
KOOLEIAC_00325 2.62e-206 - - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KOOLEIAC_00326 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KOOLEIAC_00327 8.17e-84 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Helix-hairpin-helix motif
KOOLEIAC_00328 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein
KOOLEIAC_00329 5.89e-220 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KOOLEIAC_00330 7.46e-113 tsaE - - S ko:K06925 - ko00000,ko03016 Threonylcarbamoyl adenosine biosynthesis protein TsaE
KOOLEIAC_00331 1.45e-203 yeaZ - - O ko:K14742 - ko00000,ko03016 Glycoprotease family
KOOLEIAC_00332 1.92e-134 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 FR47-like protein
KOOLEIAC_00333 6.28e-248 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KOOLEIAC_00335 1.49e-154 - - - K - - - helix_turn_helix, Lux Regulon
KOOLEIAC_00336 9.59e-305 - - - T - - - Histidine kinase
KOOLEIAC_00338 4.48e-90 - - - - - - - -
KOOLEIAC_00339 4.89e-183 - - - - ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
KOOLEIAC_00340 2.53e-181 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KOOLEIAC_00341 8.96e-252 - - - V ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KOOLEIAC_00342 1.17e-172 - - - L - - - PFAM Relaxase mobilization nuclease family protein
KOOLEIAC_00343 2.91e-182 - - - S - - - Fic/DOC family
KOOLEIAC_00345 2.14e-08 - - - K - - - Psort location Cytoplasmic, score
KOOLEIAC_00347 3.39e-153 - 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 HipA-like C-terminal domain
KOOLEIAC_00348 3.33e-66 - - - L - - - Phage integrase family
KOOLEIAC_00350 2.35e-47 - - - M - - - Peptidase family M23
KOOLEIAC_00351 0.0 - - - G - - - ABC transporter substrate-binding protein
KOOLEIAC_00352 8.16e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the isocitrate and isopropylmalate dehydrogenases family
KOOLEIAC_00353 1.25e-263 guaB3 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 IMP dehydrogenase family protein
KOOLEIAC_00354 5.83e-120 - - - - - - - -
KOOLEIAC_00355 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 long-chain-fatty acid CoA ligase
KOOLEIAC_00356 1.96e-113 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KOOLEIAC_00357 7.71e-192 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KOOLEIAC_00358 1.6e-186 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KOOLEIAC_00359 3.81e-171 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KOOLEIAC_00360 7.06e-120 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KOOLEIAC_00361 2.75e-221 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Cytidylyltransferase family
KOOLEIAC_00362 6.18e-283 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KOOLEIAC_00363 8.64e-125 - 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
KOOLEIAC_00364 2.39e-179 hisF 4.1.3.27 - E ko:K01657,ko:K02500 ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KOOLEIAC_00365 4.61e-93 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KOOLEIAC_00366 0.0 trpE 4.1.3.27 - E ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KOOLEIAC_00367 4.02e-120 - - - S ko:K09974 - ko00000 Domain of unknown function (DUF1287)
KOOLEIAC_00368 2.54e-222 - - - - - - - -
KOOLEIAC_00369 6.86e-98 - - - - - - - -
KOOLEIAC_00370 7.04e-82 - - - K - - - Protein of unknown function, DUF488
KOOLEIAC_00371 5.32e-11 - - - - - - - -
KOOLEIAC_00372 0.0 - - - E ko:K16235 - ko00000,ko02000 amino acid
KOOLEIAC_00373 7.2e-27 - - - G - - - Major facilitator Superfamily
KOOLEIAC_00374 4.67e-55 - - - EGP - - - Major Facilitator Superfamily
KOOLEIAC_00375 1.29e-121 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
KOOLEIAC_00376 8.81e-150 - - - F - - - Hydrolase of X-linked nucleoside diphosphate N terminal
KOOLEIAC_00377 1.05e-44 - - - S - - - Carbon-nitrogen hydrolase
KOOLEIAC_00379 2.36e-61 - - - K ko:K20391 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
KOOLEIAC_00380 2.12e-138 - - - - - - - -
KOOLEIAC_00381 1.21e-268 - - - S ko:K07133 - ko00000 AAA domain
KOOLEIAC_00382 8.89e-23 - - - K - - - Transcriptional regulator
KOOLEIAC_00383 4.6e-45 - - - K - - - Transcriptional regulator
KOOLEIAC_00384 2.35e-69 - - - - - - - -
KOOLEIAC_00385 1.11e-65 - - - S - - - Protein of unknown function (DUF2089)
KOOLEIAC_00386 8.85e-12 - - - T - - - Histidine kinase
KOOLEIAC_00387 2.55e-65 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
KOOLEIAC_00388 3.01e-53 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
KOOLEIAC_00389 7.81e-235 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
KOOLEIAC_00390 7.99e-119 - - - Q ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_00391 2.91e-200 - - - M - - - Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KOOLEIAC_00392 8.13e-122 - - - - - - - -
KOOLEIAC_00393 2.14e-165 - - - K - - - helix_turn_helix, Lux Regulon
KOOLEIAC_00394 1.1e-259 - - - T - - - Histidine kinase
KOOLEIAC_00395 6.56e-19 - - - T - - - Histidine kinase
KOOLEIAC_00398 1.39e-155 - - - - - - - -
KOOLEIAC_00399 4.31e-65 - - - - - - - -
KOOLEIAC_00400 6.4e-129 - - - S - - - Acetyltransferase (GNAT) domain
KOOLEIAC_00401 2.32e-44 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
KOOLEIAC_00402 4.65e-43 cefD 5.1.1.17 - E ko:K04127 ko00311,ko01100,ko01130,map00311,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Aminotransferase, class V
KOOLEIAC_00404 3.09e-243 - - - V - - - VanZ like family
KOOLEIAC_00405 0.0 - - - E ko:K16235 - ko00000,ko02000 amino acid
KOOLEIAC_00406 8.11e-201 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KOOLEIAC_00407 1.84e-170 - - - S - - - SOS response associated peptidase (SRAP)
KOOLEIAC_00408 0.0 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KOOLEIAC_00409 4.36e-208 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KOOLEIAC_00410 9.14e-239 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KOOLEIAC_00411 7.16e-155 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3-epimerase
KOOLEIAC_00412 5.07e-56 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-ATP pyrophosphohydrolase
KOOLEIAC_00413 3.56e-199 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
KOOLEIAC_00414 2.23e-136 pgsA2 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KOOLEIAC_00415 7.29e-220 - - - S - - - Bacterial protein of unknown function (DUF881)
KOOLEIAC_00416 6.08e-61 sbp - - S - - - Protein of unknown function (DUF1290)
KOOLEIAC_00417 2.65e-180 - - - S - - - Bacterial protein of unknown function (DUF881)
KOOLEIAC_00418 2.02e-97 garA - - T - - - Inner membrane component of T3SS, cytoplasmic domain
KOOLEIAC_00419 2.6e-142 merR2 - - K - - - helix_turn_helix, mercury resistance
KOOLEIAC_00420 3.74e-85 - - - - - - - -
KOOLEIAC_00421 8.55e-49 - - - - - - - -
KOOLEIAC_00422 2.61e-179 nt5e 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
KOOLEIAC_00423 3.18e-81 rbpA - - K - - - Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
KOOLEIAC_00424 0.0 helY - - L ko:K03727 - ko00000,ko01000 DEAD DEAH box helicase
KOOLEIAC_00425 4.22e-70 - - - - - - - -
KOOLEIAC_00426 0.0 - - - K - - - WYL domain
KOOLEIAC_00427 0.0 ugp 2.7.7.9 - G ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KOOLEIAC_00428 5.12e-206 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KOOLEIAC_00430 0.0 der - - F ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KOOLEIAC_00431 1.57e-184 rluB 5.4.99.19, 5.4.99.22 - J ko:K06178,ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KOOLEIAC_00432 1.34e-181 - - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KOOLEIAC_00433 2.5e-43 - - - - - - - -
KOOLEIAC_00434 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
KOOLEIAC_00435 3.41e-297 - - - - - - - -
KOOLEIAC_00436 1.7e-207 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KOOLEIAC_00437 1.2e-281 sucC 6.2.1.5 - F ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KOOLEIAC_00438 3.21e-130 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KOOLEIAC_00439 2.53e-71 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit
KOOLEIAC_00440 1.5e-254 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KOOLEIAC_00441 4.14e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KOOLEIAC_00442 4.21e-131 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KOOLEIAC_00443 1.19e-156 yebC - - K - - - transcriptional regulatory protein
KOOLEIAC_00444 3.11e-142 - 2.7.7.53 - FG ko:K19710 ko00230,map00230 ko00000,ko00001,ko01000 HIT domain
KOOLEIAC_00445 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KOOLEIAC_00451 6.22e-169 - - - S - - - PAC2 family
KOOLEIAC_00452 1.51e-201 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KOOLEIAC_00453 1.46e-197 - - - G - - - Fructosamine kinase
KOOLEIAC_00454 1.88e-273 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KOOLEIAC_00455 4.92e-245 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KOOLEIAC_00456 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
KOOLEIAC_00457 2.71e-259 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KOOLEIAC_00458 4.08e-305 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KOOLEIAC_00459 8.76e-249 - - - - - - - -
KOOLEIAC_00460 0.0 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase, class I II
KOOLEIAC_00461 2e-205 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KOOLEIAC_00462 9.3e-223 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
KOOLEIAC_00463 2.51e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
KOOLEIAC_00464 1.7e-188 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KOOLEIAC_00465 2.06e-278 pgk 2.7.2.3, 5.3.1.1 - F ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglycerate kinase
KOOLEIAC_00466 2.86e-217 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KOOLEIAC_00467 5.43e-229 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KOOLEIAC_00468 2.43e-239 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate dehydrogenase substrate binding domain
KOOLEIAC_00469 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KOOLEIAC_00470 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KOOLEIAC_00471 9.69e-295 - 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Psort location Cytoplasmic, score 8.87
KOOLEIAC_00472 8.26e-20 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KOOLEIAC_00473 2.32e-170 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KOOLEIAC_00474 9.05e-169 - - - S - - - Enoyl-(Acyl carrier protein) reductase
KOOLEIAC_00475 0.0 ybiT - - S ko:K06158 - ko00000,ko03012 ABC transporter
KOOLEIAC_00476 0.0 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KOOLEIAC_00477 1.93e-157 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KOOLEIAC_00478 1.55e-221 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
KOOLEIAC_00479 4.99e-274 - - - S - - - Psort location Cytoplasmic, score 8.87
KOOLEIAC_00480 8.87e-39 - - - - - - - -
KOOLEIAC_00481 4.64e-160 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KOOLEIAC_00482 6.9e-233 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KOOLEIAC_00483 6.76e-201 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
KOOLEIAC_00484 6.06e-224 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the OMP decarboxylase family. Type 2 subfamily
KOOLEIAC_00485 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KOOLEIAC_00486 2.61e-96 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
KOOLEIAC_00487 8.93e-229 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KOOLEIAC_00488 0.0 glnE 2.7.7.42, 2.7.7.89 - H ko:K00982 - ko00000,ko01000 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
KOOLEIAC_00489 8.46e-240 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KOOLEIAC_00490 9.57e-209 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
KOOLEIAC_00491 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KOOLEIAC_00493 1.18e-128 sixA - - T ko:K08296 - ko00000,ko01000 Phosphoglycerate mutase family
KOOLEIAC_00494 1.06e-255 trmI 2.1.1.219, 2.1.1.220 - J ko:K07442 - ko00000,ko01000,ko03016 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KOOLEIAC_00495 8.72e-172 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
KOOLEIAC_00497 4.16e-181 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KOOLEIAC_00498 8.11e-187 - - - S - - - phosphoesterase or phosphohydrolase
KOOLEIAC_00499 2.25e-116 lppD - - S - - - Appr-1'-p processing enzyme
KOOLEIAC_00500 4.13e-228 - - - I - - - alpha/beta hydrolase fold
KOOLEIAC_00502 2.24e-35 CP_1020 - - S - - - zinc ion binding
KOOLEIAC_00503 8.87e-117 CP_1020 - - S - - - zinc ion binding
KOOLEIAC_00504 1.79e-161 - - - S - - - Plasmid pRiA4b ORF-3-like protein
KOOLEIAC_00505 1.4e-43 rarD - - S ko:K05786 - ko00000,ko02000 EamA-like transporter family
KOOLEIAC_00509 4.94e-29 pinR - - L - - - resolvase
KOOLEIAC_00510 0.0 - 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Putative ATP-dependent Lon protease
KOOLEIAC_00511 0.0 - - - H - - - PglZ domain
KOOLEIAC_00512 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
KOOLEIAC_00513 0.0 - - - K - - - SIR2-like domain
KOOLEIAC_00514 0.0 - - - LV - - - DNA restriction-modification system
KOOLEIAC_00515 0.0 - - - K - - - RNA-binding protein homologous to eukaryotic snRNP
KOOLEIAC_00516 2.65e-161 - - - S - - - Domain of unknown function (DUF1788)
KOOLEIAC_00517 4.4e-136 - - - S - - - Putative inner membrane protein (DUF1819)
KOOLEIAC_00520 1.57e-192 - - - - - - - -
KOOLEIAC_00521 4.33e-95 fms 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
KOOLEIAC_00522 1.42e-209 dkg - - S - - - Oxidoreductase, aldo keto reductase family protein
KOOLEIAC_00523 1.79e-100 - - - K - - - Winged helix DNA-binding domain
KOOLEIAC_00525 8.67e-228 glkA 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KOOLEIAC_00527 0.0 - - - EGP - - - Major Facilitator Superfamily
KOOLEIAC_00528 0.0 yjjK - - S - - - ATP-binding cassette protein, ChvD family
KOOLEIAC_00529 2.1e-216 tesB - - I ko:K10805 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 Thioesterase-like superfamily
KOOLEIAC_00530 7.77e-120 - - - S - - - Protein of unknown function (DUF3180)
KOOLEIAC_00531 0.0 folK 2.7.6.3, 4.1.2.25 - H ko:K00950,ko:K13940 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KOOLEIAC_00532 7.84e-207 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KOOLEIAC_00533 3.65e-126 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
KOOLEIAC_00534 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KOOLEIAC_00535 1.54e-125 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
KOOLEIAC_00536 1.85e-265 tilS 2.4.2.8, 6.3.4.19 - J ko:K00760,ko:K04075 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KOOLEIAC_00537 0.0 dacB 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-Ala-D-Ala carboxypeptidase 3 (S13) family
KOOLEIAC_00538 0.0 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
KOOLEIAC_00539 3.45e-244 natA - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_00540 7.16e-298 - - - M - - - Glycosyl transferase family 21
KOOLEIAC_00541 0.0 - - - S - - - AI-2E family transporter
KOOLEIAC_00542 1.09e-226 - - - M - - - Glycosyltransferase like family 2
KOOLEIAC_00543 1.73e-270 fucO 1.1.1.77, 1.1.99.37, 1.2.98.1 - C ko:K00048,ko:K17067 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
KOOLEIAC_00544 0.0 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 Mycolic acid cyclopropane synthetase
KOOLEIAC_00547 1.16e-213 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KOOLEIAC_00550 7.16e-16 - - - M - - - Cell surface antigen C-terminus
KOOLEIAC_00551 0.0 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
KOOLEIAC_00552 0.0 lacZ6 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
KOOLEIAC_00553 2.07e-236 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
KOOLEIAC_00554 7.96e-224 - - - - - - - -
KOOLEIAC_00555 1.66e-161 - - - V - - - ABC transporter
KOOLEIAC_00556 1.91e-239 - - - V - - - Putative peptidoglycan binding domain
KOOLEIAC_00557 3.49e-149 - - - - - - - -
KOOLEIAC_00558 3.45e-76 - - - - - - - -
KOOLEIAC_00559 2.8e-151 - - - K - - - Transcriptional regulatory protein, C terminal
KOOLEIAC_00560 4.65e-268 - 2.7.13.3 - T ko:K18351 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 GHKL domain
KOOLEIAC_00561 5.13e-29 - - - L - - - Helix-turn-helix domain
KOOLEIAC_00562 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_00563 2.38e-272 - - - GK - - - ROK family
KOOLEIAC_00564 1.58e-07 - - - U ko:K17330 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_00565 0.0 - - - G - - - Glycosyl hydrolase family 20, domain 2
KOOLEIAC_00566 7.23e-288 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KOOLEIAC_00567 6.2e-267 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
KOOLEIAC_00568 9.79e-143 vex - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KOOLEIAC_00569 8.98e-16 - - - E - - - AzlC protein
KOOLEIAC_00570 3.51e-126 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 low molecular weight
KOOLEIAC_00571 1.46e-162 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dihydrofolate reductase
KOOLEIAC_00572 1.73e-214 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KOOLEIAC_00573 1.85e-95 - - - O - - - OsmC-like protein
KOOLEIAC_00574 1.36e-241 - - - T - - - Universal stress protein family
KOOLEIAC_00575 3.78e-143 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
KOOLEIAC_00576 4.14e-138 - - - M - - - NlpC/P60 family
KOOLEIAC_00577 2.54e-217 - - - S - - - CHAP domain
KOOLEIAC_00578 1.17e-270 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KOOLEIAC_00579 2.3e-44 - - - - - - - -
KOOLEIAC_00580 1.12e-239 senX3 2.7.13.3 - T ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
KOOLEIAC_00581 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
KOOLEIAC_00582 3.9e-178 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KOOLEIAC_00583 2.77e-222 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
KOOLEIAC_00584 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KOOLEIAC_00586 1.02e-280 - - - EGP ko:K08156,ko:K19577 - ko00000,ko02000 Major Facilitator Superfamily
KOOLEIAC_00587 0.0 - - - S - - - Domain of unknown function (DUF4037)
KOOLEIAC_00588 2.07e-148 - - - S - - - Protein of unknown function (DUF4125)
KOOLEIAC_00589 0.0 - - - S ko:K06889 - ko00000 alpha beta
KOOLEIAC_00590 6.65e-99 - - - - - - - -
KOOLEIAC_00591 0.0 pspC - - KT - - - PspC domain
KOOLEIAC_00592 2.84e-301 tcsS3 - - KT - - - PspC domain
KOOLEIAC_00593 1.01e-152 tcsR3 - - K - - - helix_turn_helix, Lux Regulon
KOOLEIAC_00594 2.65e-225 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KOOLEIAC_00595 6.93e-261 - 2.7.1.162 - S ko:K13059 - ko00000,ko01000 Phosphotransferase enzyme family
KOOLEIAC_00596 0.0 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
KOOLEIAC_00597 5.76e-217 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
KOOLEIAC_00598 1.6e-222 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_00599 2.85e-316 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_00601 1.2e-306 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KOOLEIAC_00602 8.89e-269 - - - I - - - Diacylglycerol kinase catalytic domain
KOOLEIAC_00603 1.58e-209 arbG - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
KOOLEIAC_00604 0.0 ptsG - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system, glucose-specific IIABC component
KOOLEIAC_00605 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
KOOLEIAC_00606 1.22e-249 - - - S - - - Protein conserved in bacteria
KOOLEIAC_00607 5.2e-98 - - - K - - - Transcriptional regulator
KOOLEIAC_00608 0.0 merA 1.16.1.1 - C ko:K00520,ko:K21739 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KOOLEIAC_00609 3.7e-240 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KOOLEIAC_00610 4.47e-163 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KOOLEIAC_00611 5.05e-07 - - - S - - - Mitochondrial domain of unknown function (DUF1713)
KOOLEIAC_00612 2.38e-132 - - - - - - - -
KOOLEIAC_00613 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KOOLEIAC_00614 1.03e-278 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin kinase
KOOLEIAC_00615 5.96e-284 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KOOLEIAC_00616 3.5e-107 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KOOLEIAC_00617 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KOOLEIAC_00618 2.16e-241 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KOOLEIAC_00619 2.37e-163 - - - - - - - -
KOOLEIAC_00620 2.57e-126 - - - K - - - helix_turn _helix lactose operon repressor
KOOLEIAC_00622 7.22e-195 - - - E - - - Transglutaminase/protease-like homologues
KOOLEIAC_00623 0.0 gcs2 - - S ko:K06048 - ko00000,ko01000 A circularly permuted ATPgrasp
KOOLEIAC_00624 2.1e-217 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KOOLEIAC_00625 5.53e-89 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
KOOLEIAC_00626 8.1e-236 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOOLEIAC_00627 7.34e-86 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KOOLEIAC_00628 2e-82 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KOOLEIAC_00629 1.47e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
KOOLEIAC_00630 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KOOLEIAC_00631 2.57e-128 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KOOLEIAC_00632 9.34e-317 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KOOLEIAC_00633 1.07e-98 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
KOOLEIAC_00634 3.26e-36 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30p/L7e
KOOLEIAC_00635 2.25e-129 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KOOLEIAC_00636 3.09e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KOOLEIAC_00637 1.33e-122 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KOOLEIAC_00638 3.17e-90 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KOOLEIAC_00639 7.06e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KOOLEIAC_00640 1.95e-134 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KOOLEIAC_00641 5.4e-69 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KOOLEIAC_00642 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KOOLEIAC_00643 1.11e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KOOLEIAC_00644 1.97e-49 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KOOLEIAC_00645 3.85e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KOOLEIAC_00646 1.85e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KOOLEIAC_00647 1.09e-74 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KOOLEIAC_00648 1.4e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KOOLEIAC_00649 3.85e-195 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KOOLEIAC_00650 2.54e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KOOLEIAC_00651 9.78e-151 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
KOOLEIAC_00652 1.11e-149 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KOOLEIAC_00653 9.35e-68 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KOOLEIAC_00654 1.02e-56 - - - L - - - Transposase DDE domain
KOOLEIAC_00655 1.03e-101 - - - K - - - Psort location Cytoplasmic, score
KOOLEIAC_00656 2.91e-174 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
KOOLEIAC_00657 6.73e-121 - - - S - - - YwiC-like protein
KOOLEIAC_00658 0.0 adhE 1.1.1.1, 1.2.1.10, 1.2.1.81 - C ko:K04072,ko:K15515 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
KOOLEIAC_00659 5.06e-282 - - - GK - - - transcriptional repressor of nag (N-acetylglucosamine) operon K02565
KOOLEIAC_00660 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G ko:K01214,ko:K02438 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
KOOLEIAC_00661 6.35e-213 - - - L - - - Psort location Cytoplasmic, score
KOOLEIAC_00662 1.85e-48 - - - S - - - Psort location Cytoplasmic, score
KOOLEIAC_00663 2.56e-78 - - - S - - - Protein of unknown function (DUF3801)
KOOLEIAC_00664 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Type IV secretory system Conjugative DNA transfer
KOOLEIAC_00665 4.8e-25 - - - S - - - Maff2 family
KOOLEIAC_00666 0.0 - - - J - - - Elongation factor G, domain IV
KOOLEIAC_00667 1.81e-13 - - - L - - - Transposase and inactivated derivatives IS30 family
KOOLEIAC_00668 9.6e-106 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KOOLEIAC_00669 5.33e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KOOLEIAC_00670 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
KOOLEIAC_00671 9.47e-152 - - - - - - - -
KOOLEIAC_00672 3.27e-142 yigZ - - S - - - Uncharacterized protein family UPF0029
KOOLEIAC_00673 4.76e-233 pdxB - - EH - - - Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KOOLEIAC_00674 1.04e-147 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein PGA_cap
KOOLEIAC_00675 2.72e-310 - 3.2.1.21 - G ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
KOOLEIAC_00676 5.08e-205 - - - U ko:K02026,ko:K10190 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_00677 2.42e-208 - - - U ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_00678 1.55e-311 - - - G ko:K02027,ko:K10227 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_00679 7.41e-277 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KOOLEIAC_00680 2.08e-30 - - - - - - - -
KOOLEIAC_00682 1.25e-81 - - - S ko:K11939 - ko00000,ko02000 EamA-like transporter family
KOOLEIAC_00683 3.74e-29 - - - S ko:K11939 - ko00000,ko02000 EamA-like transporter family
KOOLEIAC_00684 2.57e-304 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KOOLEIAC_00685 1.25e-285 dapC - - E - - - Aminotransferase class I and II
KOOLEIAC_00686 4.51e-79 fdxA - - C ko:K05524 - ko00000 4Fe-4S binding domain
KOOLEIAC_00687 0.0 - - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
KOOLEIAC_00688 4.96e-289 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
KOOLEIAC_00689 1.03e-34 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
KOOLEIAC_00693 1.73e-63 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KOOLEIAC_00694 1.38e-185 - - - - - - - -
KOOLEIAC_00695 2.1e-112 rimJ 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KOOLEIAC_00696 7.23e-79 ygfA 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 5-formyltetrahydrofolate cyclo-ligase family
KOOLEIAC_00697 6.24e-43 - - - S - - - Putative regulatory protein
KOOLEIAC_00698 2.79e-137 - - - NO - - - SAF
KOOLEIAC_00699 6.79e-24 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
KOOLEIAC_00700 0.0 - - - L - - - Superfamily I DNA and RNA helicases and helicase subunits
KOOLEIAC_00701 4.22e-281 - - - T - - - Forkhead associated domain
KOOLEIAC_00702 1.06e-73 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KOOLEIAC_00703 2.41e-113 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KOOLEIAC_00704 5.66e-186 - - - S - - - alpha beta
KOOLEIAC_00705 0.0 - - - S ko:K06901 - ko00000,ko02000 Permease family
KOOLEIAC_00706 5.71e-172 - - - L - - - Winged helix-turn helix
KOOLEIAC_00707 3.34e-114 - - - - - - - -
KOOLEIAC_00708 9.8e-223 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
KOOLEIAC_00709 4.27e-166 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_00710 2.62e-152 - - - M - - - Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KOOLEIAC_00711 1.36e-26 - - - L - - - Helix-turn-helix domain
KOOLEIAC_00712 7.09e-79 - - - L - - - Transposase and inactivated derivatives IS30 family
KOOLEIAC_00713 4.51e-190 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KOOLEIAC_00714 1.86e-221 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
KOOLEIAC_00715 6.67e-212 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KOOLEIAC_00716 1.34e-259 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import
KOOLEIAC_00717 1.5e-182 regX3 - - KT ko:K07776 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
KOOLEIAC_00718 5.73e-270 phoR 2.7.13.3 - T ko:K07636,ko:K07768 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
KOOLEIAC_00719 1.95e-307 - - - EGP - - - Sugar (and other) transporter
KOOLEIAC_00720 1.48e-159 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KOOLEIAC_00721 9.45e-300 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KOOLEIAC_00722 9.37e-277 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KOOLEIAC_00723 0.0 pepC2 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
KOOLEIAC_00724 6.94e-120 - - - D - - - nuclear chromosome segregation
KOOLEIAC_00725 6.14e-162 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KOOLEIAC_00726 3.28e-194 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21681 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KOOLEIAC_00727 8.66e-254 yfiH - - Q ko:K05810 - ko00000,ko01000 Multi-copper polyphenol oxidoreductase laccase
KOOLEIAC_00728 0.0 - - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase family U32 C-terminal domain
KOOLEIAC_00729 4.61e-223 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KOOLEIAC_00730 3.34e-132 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Conserved hypothetical protein 95
KOOLEIAC_00731 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 helicase superfamily c-terminal domain
KOOLEIAC_00732 1.05e-40 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
KOOLEIAC_00733 7.63e-249 - - - G - - - pfkB family carbohydrate kinase
KOOLEIAC_00734 9.23e-305 - - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
KOOLEIAC_00735 1.54e-166 - - - K - - - helix_turn_helix, mercury resistance
KOOLEIAC_00736 1.41e-79 - - - T - - - Toxic component of a toxin-antitoxin (TA) module
KOOLEIAC_00737 7.21e-72 - - - L - - - RelB antitoxin
KOOLEIAC_00738 1.67e-34 yxiO - - G ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Major facilitator Superfamily
KOOLEIAC_00739 4.93e-245 - - - K - - - Helix-turn-helix XRE-family like proteins
KOOLEIAC_00740 3.04e-32 - - - - - - - -
KOOLEIAC_00741 8.42e-135 - - - S - - - Alpha/beta hydrolase family
KOOLEIAC_00746 0.0 fas - - I ko:K11533 ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931 ko00000,ko00001,ko00002,ko01000,ko01004 Beta-ketoacyl synthase, C-terminal domain
KOOLEIAC_00747 0.0 pccB - - I - - - Carboxyl transferase domain
KOOLEIAC_00748 0.0 accC 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K11263 ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase L chain, ATP binding domain protein
KOOLEIAC_00749 9.64e-119 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
KOOLEIAC_00750 8.21e-189 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
KOOLEIAC_00751 0.0 - - - - - - - -
KOOLEIAC_00752 3.74e-211 - - - QT - - - PucR C-terminal helix-turn-helix domain
KOOLEIAC_00753 1.75e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KOOLEIAC_00754 5e-96 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KOOLEIAC_00755 9.79e-188 - - - K - - - Psort location Cytoplasmic, score
KOOLEIAC_00756 1.99e-176 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KOOLEIAC_00757 4.95e-44 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KOOLEIAC_00759 2.38e-293 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
KOOLEIAC_00760 2.81e-297 - - - G - - - polysaccharide deacetylase
KOOLEIAC_00761 1.93e-252 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KOOLEIAC_00762 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KOOLEIAC_00763 1.44e-51 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L27 protein
KOOLEIAC_00764 1.01e-62 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
KOOLEIAC_00765 0.0 rne 3.1.26.12 - J ko:K08300,ko:K08301 ko03018,map03018 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 Ribonuclease E/G family
KOOLEIAC_00766 3.47e-293 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
KOOLEIAC_00767 1.52e-211 - - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
KOOLEIAC_00768 9.96e-213 - 4.1.2.28 - EM ko:K22397 ko00040,map00040 ko00000,ko00001,ko01000 Dihydrodipicolinate synthetase family
KOOLEIAC_00769 1.15e-190 - - - S ko:K07046 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Amidohydrolase
KOOLEIAC_00770 9.55e-271 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
KOOLEIAC_00771 8.73e-190 - 1.1.1.100, 1.1.1.413 - IQ ko:K00059,ko:K18333,ko:K22322 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
KOOLEIAC_00772 0.0 - 4.2.1.68 - M ko:K18334 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Enolase C-terminal domain-like
KOOLEIAC_00773 4.75e-245 - - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
KOOLEIAC_00774 0.0 - - - V - - - Efflux ABC transporter, permease protein
KOOLEIAC_00775 5.87e-176 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_00776 3.47e-38 - - - S - - - Protein of unknown function (DUF1778)
KOOLEIAC_00777 4.05e-119 - - - K - - - Acetyltransferase (GNAT) family
KOOLEIAC_00778 0.0 maf - - DF ko:K06287 - ko00000 Maf-like protein
KOOLEIAC_00779 7.94e-232 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KOOLEIAC_00780 1.31e-302 hom 1.1.1.3, 2.7.2.4 - E ko:K00003,ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
KOOLEIAC_00781 1.44e-65 nagE 2.7.1.193 - G ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
KOOLEIAC_00782 3.8e-73 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KOOLEIAC_00783 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KOOLEIAC_00784 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
KOOLEIAC_00785 4.49e-169 - - - K - - - Bacterial regulatory proteins, tetR family
KOOLEIAC_00786 4.02e-282 - - - G - - - Transmembrane secretion effector
KOOLEIAC_00787 0.0 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KOOLEIAC_00788 0.0 nox - - C - - - Pyridine nucleotide-disulphide oxidoreductase
KOOLEIAC_00789 1.07e-200 - - - ET ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KOOLEIAC_00790 8.62e-155 - - - P ko:K16958 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_00791 1.55e-178 - - - P ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_00792 1.68e-132 - - - S - - - L-2-amino-thiazoline-4-carboxylic acid hydrolase
KOOLEIAC_00793 9.29e-169 - - - E ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_00794 4.65e-277 pyr 1.3.98.1 - F ko:K00226 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroorotate dehydrogenase
KOOLEIAC_00795 2.57e-47 - - - T - - - Histidine kinase
KOOLEIAC_00796 1.13e-16 - - - S ko:K08981 - ko00000 Bacterial PH domain
KOOLEIAC_00797 1.9e-170 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KOOLEIAC_00798 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KOOLEIAC_00799 2.37e-181 ltbR - - K - - - Transcriptional regulator, IclR family, C-terminal domain protein
KOOLEIAC_00800 0.0 - - - S - - - Calcineurin-like phosphoesterase
KOOLEIAC_00801 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KOOLEIAC_00802 0.0 mutT 3.6.1.55 - LT ko:K03574 - ko00000,ko01000,ko03400 Phosphoglycerate mutase family
KOOLEIAC_00803 1.47e-177 - - - - - - - -
KOOLEIAC_00804 0.0 - - - G - - - N-terminal domain of (some) glycogen debranching enzymes
KOOLEIAC_00805 1.22e-177 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_00806 3.73e-267 - - - U ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_00807 6.84e-264 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_00808 1.85e-164 - - - K - - - helix_turn _helix lactose operon repressor
KOOLEIAC_00809 5.1e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KOOLEIAC_00810 1.05e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KOOLEIAC_00811 1.81e-274 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
KOOLEIAC_00812 2.38e-277 gluQ 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KOOLEIAC_00814 0.0 clpB - - O ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KOOLEIAC_00815 1.15e-208 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
KOOLEIAC_00816 7.26e-203 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
KOOLEIAC_00817 8.56e-161 - - - S - - - Domain of unknown function (DUF4190)
KOOLEIAC_00818 7.55e-220 - - - - - - - -
KOOLEIAC_00819 4.86e-299 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
KOOLEIAC_00820 9.88e-57 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 sugar phosphate isomerase involved in capsule formation
KOOLEIAC_00821 2.23e-71 - - - G - - - Branched-chain amino acid transport system / permease component
KOOLEIAC_00822 7.05e-96 - - - P - - - branched-chain amino acid ABC transporter, permease protein
KOOLEIAC_00823 3.85e-144 - - - G - - - ATPases associated with a variety of cellular activities
KOOLEIAC_00824 5.19e-98 - - - G - - - ABC-type sugar transport system periplasmic component
KOOLEIAC_00825 6.75e-212 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
KOOLEIAC_00826 1.14e-89 xylR - - GK - - - ROK family
KOOLEIAC_00827 1.5e-47 - - - - - - - -
KOOLEIAC_00828 3.39e-255 - - - M - - - Glycosyltransferase like family 2
KOOLEIAC_00829 1.24e-227 - - - S - - - Predicted membrane protein (DUF2142)
KOOLEIAC_00830 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
KOOLEIAC_00831 0.0 - - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferase family 2
KOOLEIAC_00832 2.23e-206 - - - GM ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KOOLEIAC_00833 1.16e-152 tagG - - U ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
KOOLEIAC_00834 5.34e-215 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KOOLEIAC_00835 0.0 rfbD 1.1.1.133, 5.1.3.13 - M ko:K00067,ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KOOLEIAC_00836 1.69e-262 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KOOLEIAC_00837 0.0 - - - - - - - -
KOOLEIAC_00838 1e-213 - - - M - - - Glycosyl transferase family 2
KOOLEIAC_00839 3.74e-39 - - - M - - - nuclease
KOOLEIAC_00840 3.87e-99 - - - M - - - L,D-transpeptidase catalytic domain
KOOLEIAC_00841 7.78e-237 - - - M - - - Glycosyl hydrolases family 25
KOOLEIAC_00842 1.14e-309 yvhJ - - K - - - Cell envelope-related transcriptional attenuator domain
KOOLEIAC_00843 0.0 - - - V - - - ABC transporter permease
KOOLEIAC_00844 4.41e-242 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KOOLEIAC_00845 1.57e-183 - - - T ko:K06950 - ko00000 HD domain
KOOLEIAC_00846 1.73e-205 - - - S - - - Glutamine amidotransferase domain
KOOLEIAC_00847 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
KOOLEIAC_00848 3.31e-238 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
KOOLEIAC_00849 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
KOOLEIAC_00850 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
KOOLEIAC_00851 2.05e-28 - - - S ko:K06921 - ko00000 ATPase domain predominantly from Archaea
KOOLEIAC_00852 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
KOOLEIAC_00853 8.8e-55 - - - G - - - Glycosyl hydrolases family 43
KOOLEIAC_00854 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
KOOLEIAC_00855 0.0 oppD - - P ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KOOLEIAC_00856 3.22e-222 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
KOOLEIAC_00857 4.8e-226 oppB1 - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_00858 0.0 - 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
KOOLEIAC_00859 3.49e-63 - - - - - - - -
KOOLEIAC_00860 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KOOLEIAC_00861 5.33e-156 - - - - - - - -
KOOLEIAC_00862 4.51e-237 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KOOLEIAC_00864 0.0 - - - G - - - MFS/sugar transport protein
KOOLEIAC_00865 5.04e-230 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KOOLEIAC_00866 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
KOOLEIAC_00867 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
KOOLEIAC_00868 3.31e-120 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
KOOLEIAC_00869 0.0 - - - E ko:K03293 - ko00000 Amino acid permease
KOOLEIAC_00870 2.31e-15 - - - S ko:K19158 - ko00000,ko01000,ko02048 YoeB-like toxin of bacterial type II toxin-antitoxin system
KOOLEIAC_00871 1.62e-44 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
KOOLEIAC_00872 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
KOOLEIAC_00873 3.55e-39 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 ThiS family
KOOLEIAC_00874 5.07e-202 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KOOLEIAC_00875 3.98e-189 thiF 2.7.7.73, 2.7.7.80, 2.8.1.11 - H ko:K03148,ko:K21147 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
KOOLEIAC_00876 1.02e-81 - - - P - - - Rhodanese Homology Domain
KOOLEIAC_00877 2.82e-132 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KOOLEIAC_00878 9.39e-181 - - - S - - - Putative ABC-transporter type IV
KOOLEIAC_00879 3.65e-100 - - - S - - - Protein of unknown function (DUF975)
KOOLEIAC_00880 0.0 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KOOLEIAC_00881 1.77e-271 - - - L - - - Tetratricopeptide repeat
KOOLEIAC_00882 1.39e-256 - - - G - - - Haloacid dehalogenase-like hydrolase
KOOLEIAC_00884 7.1e-177 tlyA 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
KOOLEIAC_00885 1.89e-151 - - - - - - - -
KOOLEIAC_00886 5.06e-64 trkA - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
KOOLEIAC_00887 1.35e-236 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KOOLEIAC_00888 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KOOLEIAC_00889 7.77e-151 - - - S - - - Haloacid dehalogenase-like hydrolase
KOOLEIAC_00890 8.44e-70 - - - J - - - Acetyltransferase (GNAT) domain
KOOLEIAC_00891 3.46e-78 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
KOOLEIAC_00892 6.07e-223 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_00893 3.91e-155 - - - S - - - ABC-2 family transporter protein
KOOLEIAC_00894 9.93e-126 - - - S - - - ABC-2 family transporter protein
KOOLEIAC_00895 6.51e-101 - 3.6.3.8 - P ko:K01537 - ko00000,ko01000 ATPase, P-type (transporting), HAD superfamily, subfamily IC
KOOLEIAC_00896 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase N terminus
KOOLEIAC_00897 5.12e-288 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KOOLEIAC_00898 7.62e-126 - - - - - - - -
KOOLEIAC_00899 1.1e-177 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KOOLEIAC_00900 2.08e-115 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
KOOLEIAC_00901 3.65e-30 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
KOOLEIAC_00902 0.0 - - - S ko:K09118 - ko00000 Uncharacterised protein family (UPF0182)
KOOLEIAC_00903 1.65e-121 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
KOOLEIAC_00904 4.23e-147 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KOOLEIAC_00905 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KOOLEIAC_00906 1.12e-212 - - - C - - - Aldo/keto reductase family
KOOLEIAC_00907 2.49e-313 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KOOLEIAC_00908 4.64e-114 - - - D - - - Septum formation initiator
KOOLEIAC_00909 3.24e-132 - - - S ko:K09009 - ko00000 Protein of unknown function (DUF501)
KOOLEIAC_00910 2.6e-233 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
KOOLEIAC_00912 1.16e-121 - - - - - - - -
KOOLEIAC_00913 0.0 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase alpha chain
KOOLEIAC_00914 8.17e-98 fkbP 5.2.1.8 - G ko:K01802 - ko00000,ko01000 Peptidyl-prolyl cis-trans
KOOLEIAC_00915 7.1e-106 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KOOLEIAC_00916 5.89e-193 hlyIII - - S ko:K11068 - ko00000,ko02042 Haemolysin-III related
KOOLEIAC_00917 0.0 pdtaS 2.7.13.3 - T ko:K00936 - ko00000,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
KOOLEIAC_00918 8.13e-62 whiB - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KOOLEIAC_00919 0.0 - - - D ko:K03466 - ko00000,ko03036 FtsK/SpoIIIE family
KOOLEIAC_00920 6.52e-306 lytR2 - - K - - - Cell envelope-related transcriptional attenuator domain
KOOLEIAC_00921 2.06e-74 whiB2 - - K ko:K18955 - ko00000,ko03000 Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KOOLEIAC_00922 0.0 - - - S - - - Glycosyl transferase, family 2
KOOLEIAC_00923 0.0 - - - - - - - -
KOOLEIAC_00924 1.23e-100 - - - S - - - Zincin-like metallopeptidase
KOOLEIAC_00925 1.69e-189 - - - T - - - Eukaryotic phosphomannomutase
KOOLEIAC_00926 2.02e-145 pyrE_1 - - S - - - Phosphoribosyl transferase domain
KOOLEIAC_00927 1.94e-247 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
KOOLEIAC_00928 1.95e-161 cseB - - T - - - Response regulator receiver domain protein
KOOLEIAC_00929 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KOOLEIAC_00930 2.16e-130 carD - - K ko:K07736 - ko00000,ko03000 CarD-like/TRCF domain
KOOLEIAC_00931 5.08e-114 ispF 2.7.7.60, 4.6.1.12 - H ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KOOLEIAC_00932 7.76e-175 znuB - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
KOOLEIAC_00933 5.24e-206 - - - P ko:K02074 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_00934 7.86e-266 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
KOOLEIAC_00935 6.48e-211 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KOOLEIAC_00937 0.0 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
KOOLEIAC_00938 8.79e-148 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KOOLEIAC_00939 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KOOLEIAC_00940 2.2e-227 terC - - P ko:K05794 - ko00000 Integral membrane protein, TerC family
KOOLEIAC_00941 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase
KOOLEIAC_00942 1.12e-142 aspA 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
KOOLEIAC_00944 1.77e-168 pdtaR - - T ko:K22010 - ko00000,ko00002,ko02022 Response regulator receiver domain protein
KOOLEIAC_00945 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KOOLEIAC_00946 4.64e-227 - - - L - - - NIF3 (NGG1p interacting factor 3)
KOOLEIAC_00947 4e-162 - - - L - - - NUDIX domain
KOOLEIAC_00948 0.0 glgX 3.2.1.68 CBM48,GH13 G ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
KOOLEIAC_00949 2.67e-35 zntR - - K - - - bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
KOOLEIAC_00950 1.43e-115 - - - K - - - Putative zinc ribbon domain
KOOLEIAC_00951 1.78e-161 - - - S - - - GyrI-like small molecule binding domain
KOOLEIAC_00952 1.12e-28 - 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
KOOLEIAC_00953 9.25e-21 - - - K - - - Helix-turn-helix domain
KOOLEIAC_00954 2.57e-48 - - - - ko:K03646 - ko00000,ko02000 -
KOOLEIAC_00955 2.57e-13 - - - - - - - -
KOOLEIAC_00956 7.32e-80 - - - D ko:K03466 - ko00000,ko03036 ftsk spoiiie
KOOLEIAC_00961 8.08e-121 - - - L - - - Phage integrase family
KOOLEIAC_00963 1.83e-156 - - - - - - - -
KOOLEIAC_00964 3.26e-274 - - - - - - - -
KOOLEIAC_00965 0.0 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KOOLEIAC_00966 8.03e-296 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KOOLEIAC_00967 0.0 pta 2.3.1.8 - C ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphate acetyltransferase
KOOLEIAC_00969 4.78e-245 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KOOLEIAC_00970 0.0 yrhL - - I - - - Psort location CytoplasmicMembrane, score 9.99
KOOLEIAC_00971 3.02e-152 - - - - - - - -
KOOLEIAC_00972 3.5e-64 - - - - - - - -
KOOLEIAC_00975 1.45e-157 - - - O - - - AAA domain (Cdc48 subfamily)
KOOLEIAC_00976 1.12e-83 - - - - - - - -
KOOLEIAC_00978 3.35e-47 - - - L - - - Phage integrase, N-terminal SAM-like domain
KOOLEIAC_00979 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KOOLEIAC_00980 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
KOOLEIAC_00981 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KOOLEIAC_00982 5.45e-86 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KOOLEIAC_00983 7.2e-174 gpmB 3.1.3.85, 5.4.2.11 - G ko:K01834,ko:K22306 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
KOOLEIAC_00986 1.15e-200 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KOOLEIAC_00987 4.44e-226 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
KOOLEIAC_00988 5.69e-280 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KOOLEIAC_00989 6.46e-145 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_00990 6.61e-284 - - - S - - - Peptidase dimerisation domain
KOOLEIAC_00991 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KOOLEIAC_00992 6.14e-52 - - - - - - - -
KOOLEIAC_00993 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
KOOLEIAC_00994 5.19e-222 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KOOLEIAC_00995 7.83e-153 - - - S - - - Protein of unknown function (DUF3000)
KOOLEIAC_00996 0.0 rnd 3.1.13.5 - J ko:K03684 - ko00000,ko01000,ko03016 3'-5' exonuclease
KOOLEIAC_00997 3.47e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KOOLEIAC_00998 4.13e-311 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
KOOLEIAC_00999 4.53e-79 - - - - - - - -
KOOLEIAC_01000 2.96e-151 clpP1 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KOOLEIAC_01001 1.28e-155 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KOOLEIAC_01002 0.0 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KOOLEIAC_01005 5.51e-308 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
KOOLEIAC_01006 7.12e-310 nhaA - - P ko:K03313 - ko00000,ko02000 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KOOLEIAC_01007 1.86e-214 fmt2 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
KOOLEIAC_01008 3.95e-147 safC - - S - - - O-methyltransferase
KOOLEIAC_01009 3.43e-234 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
KOOLEIAC_01010 0.0 sdhA 1.3.5.1, 1.3.5.4, 1.4.3.16 - C ko:K00239,ko:K00278 ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 Succinate dehydrogenase flavoprotein subunit
KOOLEIAC_01011 0.0 dprA - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
KOOLEIAC_01012 0.0 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI C-terminal
KOOLEIAC_01013 8.76e-99 yraN - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
KOOLEIAC_01014 3.1e-29 - - - L - - - Transposase and inactivated derivatives IS30 family
KOOLEIAC_01015 6.48e-210 pdxY 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
KOOLEIAC_01016 0.0 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Aminotransferase class-V
KOOLEIAC_01017 2.55e-216 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KOOLEIAC_01018 0.0 - - - MV ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
KOOLEIAC_01019 1.43e-180 - - - K - - - helix_turn_helix, Lux Regulon
KOOLEIAC_01020 0.0 - - - T - - - Histidine kinase
KOOLEIAC_01021 0.0 pip 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 alpha/beta hydrolase fold
KOOLEIAC_01022 6.61e-190 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KOOLEIAC_01023 3.42e-199 glnH - - ET ko:K02030,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
KOOLEIAC_01024 6.4e-176 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ATP binding protein of ABC transporter for glutamate aspartate K02028
KOOLEIAC_01025 6.48e-153 glnP - - E ko:K02029,ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01026 9.65e-143 glnP2 - - E ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01027 9.82e-257 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KOOLEIAC_01028 2.72e-300 - - - K - - - Fic/DOC family
KOOLEIAC_01029 1.57e-78 yccF - - S - - - Inner membrane component domain
KOOLEIAC_01030 6.44e-205 - - - J - - - Methyltransferase domain
KOOLEIAC_01031 1.67e-110 - - - S - - - Cupin 2, conserved barrel domain protein
KOOLEIAC_01032 5.72e-69 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
KOOLEIAC_01033 5.09e-51 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
KOOLEIAC_01034 5.37e-310 - - - S - - - HipA-like C-terminal domain
KOOLEIAC_01035 5.82e-22 - - - K ko:K21498 - ko00000,ko02048 addiction module antidote protein HigA
KOOLEIAC_01036 8.02e-278 - - - G - - - Transmembrane secretion effector
KOOLEIAC_01037 4.23e-154 - - - K - - - Bacterial regulatory proteins, tetR family
KOOLEIAC_01038 2.7e-17 - - - - - - - -
KOOLEIAC_01039 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
KOOLEIAC_01040 2.58e-34 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
KOOLEIAC_01041 3.21e-306 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KOOLEIAC_01042 1.53e-307 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
KOOLEIAC_01043 1.44e-187 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KOOLEIAC_01044 2.46e-222 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KOOLEIAC_01045 2.51e-280 - - - GK - - - ROK family
KOOLEIAC_01046 1.47e-205 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
KOOLEIAC_01047 0.0 gtr - - U ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Sugar (and other) transporter
KOOLEIAC_01048 0.0 - - - P - - - Domain of unknown function (DUF4976)
KOOLEIAC_01049 0.0 - - - C ko:K06871 - ko00000 Iron-sulfur cluster-binding domain
KOOLEIAC_01050 3.4e-152 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
KOOLEIAC_01051 1.07e-69 - - - L - - - Helix-turn-helix domain
KOOLEIAC_01052 5.56e-55 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
KOOLEIAC_01053 1.02e-76 - - - L ko:K07483 - ko00000 Integrase core domain
KOOLEIAC_01054 1.91e-166 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
KOOLEIAC_01055 1.38e-82 gloA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KOOLEIAC_01057 1.05e-308 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
KOOLEIAC_01058 6.52e-139 - - - E - - - haloacid dehalogenase-like hydrolase
KOOLEIAC_01059 1.72e-207 - - - G - - - Phosphoglycerate mutase family
KOOLEIAC_01060 1.15e-296 rutG - - F ko:K02824,ko:K03458 - ko00000,ko02000 Permease family
KOOLEIAC_01061 0.0 - - - JKL - - - helicase superfamily c-terminal domain
KOOLEIAC_01062 0.0 nplT 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
KOOLEIAC_01063 1.78e-241 pitB - - P ko:K03306 - ko00000 Phosphate transporter family
KOOLEIAC_01064 2.62e-145 - - - P ko:K07220 - ko00000 Protein of unknown function DUF47
KOOLEIAC_01065 3.4e-146 - - - K - - - helix_turn_helix, Lux Regulon
KOOLEIAC_01066 1.38e-309 - - - T - - - Histidine kinase
KOOLEIAC_01067 2.56e-148 - 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
KOOLEIAC_01068 7.53e-239 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_01069 9.97e-287 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KOOLEIAC_01070 0.0 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KOOLEIAC_01071 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
KOOLEIAC_01072 2.12e-83 - - - E - - - GDSL-like Lipase/Acylhydrolase family
KOOLEIAC_01073 8.29e-25 - - - L - - - Transposase and inactivated derivatives IS30 family
KOOLEIAC_01074 1.74e-128 - - - L - - - Transposase and inactivated derivatives IS30 family
KOOLEIAC_01075 1.44e-86 - - - L - - - Transposase and inactivated derivatives IS30 family
KOOLEIAC_01076 5.01e-228 - - - P ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01077 9.95e-215 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01078 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
KOOLEIAC_01079 0.0 - 3.2.1.45 GH30 G ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 TIM-barrel domain
KOOLEIAC_01080 1.67e-152 - - - S - - - Protein of unknown function, DUF624
KOOLEIAC_01081 2.05e-155 - - - K - - - Bacterial regulatory proteins, tetR family
KOOLEIAC_01082 0.0 bgl2 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
KOOLEIAC_01083 0.0 lacZ3 3.2.1.31 - G ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 2 family
KOOLEIAC_01087 1.94e-248 - - - L - - - Transposase and inactivated derivatives IS30 family
KOOLEIAC_01088 7.64e-13 - - - S ko:K09136 - ko00000,ko03009 ATP diphosphatase activity
KOOLEIAC_01089 2.9e-260 - - - - - - - -
KOOLEIAC_01090 1.15e-139 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Peptidase family S51
KOOLEIAC_01091 4.41e-144 pncA 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Isochorismatase family
KOOLEIAC_01092 2.97e-216 - - - M - - - pfam nlp p60
KOOLEIAC_01093 7.74e-197 - - - I - - - Serine aminopeptidase, S33
KOOLEIAC_01094 5.43e-41 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
KOOLEIAC_01095 1.88e-70 - - - S - - - Protein of unknown function (DUF2975)
KOOLEIAC_01096 3.51e-308 pbuX - - F ko:K03458 - ko00000 Permease family
KOOLEIAC_01097 3.1e-137 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KOOLEIAC_01098 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KOOLEIAC_01099 2.11e-80 - - - S - - - Domain of unknown function (DUF4418)
KOOLEIAC_01100 9.39e-277 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KOOLEIAC_01101 2.94e-208 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KOOLEIAC_01102 5.26e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KOOLEIAC_01103 4.04e-198 - - - S ko:K07010 - ko00000,ko01002 Peptidase C26
KOOLEIAC_01104 1.43e-115 - 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 cytidine deaminase activity
KOOLEIAC_01105 3.53e-66 - - - S - - - SdpI/YhfL protein family
KOOLEIAC_01106 1.03e-143 - - - E - - - Transglutaminase-like superfamily
KOOLEIAC_01107 1.01e-83 - - - T - - - PemK-like, MazF-like toxin of type II toxin-antitoxin system
KOOLEIAC_01108 4.77e-61 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
KOOLEIAC_01109 5.73e-165 - 5.4.2.12 - G ko:K15634 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoglycerate mutase family
KOOLEIAC_01110 1.28e-76 - - - S - - - Bacterial protein of unknown function (DUF948)
KOOLEIAC_01111 6.59e-48 - - - - - - - -
KOOLEIAC_01112 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KOOLEIAC_01113 2.12e-99 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KOOLEIAC_01114 1.04e-252 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KOOLEIAC_01115 1.01e-90 - 3.4.23.43 - S ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type IV leader peptidase family
KOOLEIAC_01116 6.12e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KOOLEIAC_01117 0.0 aroB 2.7.1.71, 4.2.3.4 - H ko:K01735,ko:K13829 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KOOLEIAC_01118 8.53e-104 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
KOOLEIAC_01119 1.07e-121 - - - K - - - Psort location Cytoplasmic, score
KOOLEIAC_01120 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KOOLEIAC_01121 0.0 - - - S - - - L,D-transpeptidase catalytic domain
KOOLEIAC_01122 0.0 sufB - - O ko:K09014 - ko00000 FeS assembly protein SufB
KOOLEIAC_01123 7.19e-300 sufD - - O ko:K09015 - ko00000 FeS assembly protein SufD
KOOLEIAC_01124 2.81e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
KOOLEIAC_01125 2.53e-302 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KOOLEIAC_01126 8.33e-133 iscU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
KOOLEIAC_01127 2.19e-142 - - - S - - - Iron-sulfur cluster assembly protein
KOOLEIAC_01128 1.6e-309 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KOOLEIAC_01129 1.31e-210 spoU2 - - J - - - SpoU rRNA Methylase family
KOOLEIAC_01131 2.55e-174 - 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KOOLEIAC_01132 2.76e-76 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
KOOLEIAC_01133 1.14e-276 phoH - - T ko:K06217 - ko00000 PhoH-like protein
KOOLEIAC_01134 1.33e-133 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KOOLEIAC_01135 0.0 corC - - S - - - CBS domain
KOOLEIAC_01136 3.7e-234 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KOOLEIAC_01137 0.0 fadD2 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
KOOLEIAC_01138 7.75e-260 pntA 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 NAD(P) transhydrogenase subunit alpha part 1 K00324
KOOLEIAC_01139 3.55e-58 pntAB 1.6.1.2 - C ko:K00324 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 4TM region of pyridine nucleotide transhydrogenase, mitoch
KOOLEIAC_01140 2.11e-308 pntB 1.6.1.2 - C ko:K00325 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KOOLEIAC_01141 3.57e-299 - - - EGP ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
KOOLEIAC_01142 2.59e-137 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KOOLEIAC_01143 2.72e-288 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Amino-transferase class IV
KOOLEIAC_01144 5.65e-185 mazG 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 Psort location Cytoplasmic, score 8.87
KOOLEIAC_01145 3.96e-178 - - - S - - - UPF0126 domain
KOOLEIAC_01146 4.75e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
KOOLEIAC_01147 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KOOLEIAC_01148 0.0 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
KOOLEIAC_01150 1.59e-243 - - - K - - - helix_turn _helix lactose operon repressor
KOOLEIAC_01151 5.37e-76 - - - K - - - helix_turn _helix lactose operon repressor
KOOLEIAC_01152 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase NADPH large subunit
KOOLEIAC_01153 0.0 gltD 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
KOOLEIAC_01154 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
KOOLEIAC_01155 0.0 - - - S - - - Glycosyl hydrolases related to GH101 family, GH129
KOOLEIAC_01156 1.7e-106 - - - - - - - -
KOOLEIAC_01157 2.77e-311 glgA 2.4.1.342 GT4 G ko:K16148 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000,ko01003 Starch synthase catalytic domain
KOOLEIAC_01158 1.2e-201 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_01159 1.71e-205 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KOOLEIAC_01161 2.92e-99 - - - G ko:K02445,ko:K03762 - ko00000,ko02000 transmembrane transporter activity
KOOLEIAC_01163 5.26e-262 - - - EGP - - - Major facilitator Superfamily
KOOLEIAC_01164 7.18e-84 - - - L - - - Transposase, Mutator family
KOOLEIAC_01165 4.22e-136 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Redoxin
KOOLEIAC_01166 3.48e-181 - - - - - - - -
KOOLEIAC_01168 1.22e-154 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
KOOLEIAC_01169 6.95e-103 - - - K - - - SIR2-like domain
KOOLEIAC_01170 2.55e-76 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
KOOLEIAC_01171 7.43e-39 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
KOOLEIAC_01173 6.44e-49 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
KOOLEIAC_01174 1.22e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KOOLEIAC_01175 1.86e-211 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KOOLEIAC_01176 1.32e-271 - - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
KOOLEIAC_01177 1.08e-196 - - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KOOLEIAC_01178 3.59e-240 - - - U ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KOOLEIAC_01179 3.88e-205 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
KOOLEIAC_01180 9.68e-159 livF - - E ko:K01995,ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_01181 2.92e-153 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Belongs to the SUA5 family
KOOLEIAC_01182 8.31e-276 rfe 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 4
KOOLEIAC_01183 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KOOLEIAC_01184 1.84e-154 orn - - L ko:K13288 ko03008,map03008 ko00000,ko00001,ko01000,ko03009,ko03019 3'-to-5' exoribonuclease specific for small oligoribonucleotides
KOOLEIAC_01185 0.0 - - - L - - - PIF1-like helicase
KOOLEIAC_01186 1.03e-197 - 1.97.1.4 - O ko:K04069 - ko00000,ko01000 Radical SAM superfamily
KOOLEIAC_01187 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KOOLEIAC_01188 3.81e-151 ssb2 - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
KOOLEIAC_01189 0.0 pepO 3.4.24.11, 3.4.24.71 - O ko:K01389,ko:K01415,ko:K07386 ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase family M13
KOOLEIAC_01190 2.91e-199 - - - S - - - Short repeat of unknown function (DUF308)
KOOLEIAC_01191 1.25e-192 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
KOOLEIAC_01192 9.67e-317 gltA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Citrate synthase, C-terminal domain
KOOLEIAC_01193 3.06e-219 dapD 2.3.1.117 - E ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
KOOLEIAC_01194 0.0 - - - KL - - - Psort location Cytoplasmic, score 8.87
KOOLEIAC_01195 1.5e-129 - - - K - - - Acetyltransferase (GNAT) domain
KOOLEIAC_01196 5.24e-116 vsr - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
KOOLEIAC_01197 9.06e-259 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
KOOLEIAC_01198 3.68e-298 aspB 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K08969,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
KOOLEIAC_01199 9.73e-228 ppx1 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
KOOLEIAC_01200 1.21e-268 - - - S ko:K18353 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01504 Endonuclease/Exonuclease/phosphatase family
KOOLEIAC_01202 1.28e-102 - - - F - - - Nucleoside 2-deoxyribosyltransferase
KOOLEIAC_01203 8.52e-91 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KOOLEIAC_01204 0.0 fadD3 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
KOOLEIAC_01205 7.97e-117 ywrO - - S - - - Flavodoxin-like fold
KOOLEIAC_01206 8.78e-54 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KOOLEIAC_01207 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KOOLEIAC_01208 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
KOOLEIAC_01209 2.69e-173 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KOOLEIAC_01210 0.0 hgdC - - I - - - CoA enzyme activase uncharacterised domain (DUF2229)
KOOLEIAC_01211 0.0 egtA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Glutamate-cysteine ligase family 2(GCS2)
KOOLEIAC_01212 7.19e-179 - - - K - - - Bacterial regulatory proteins, tetR family
KOOLEIAC_01213 0.0 bgl2 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
KOOLEIAC_01214 3.36e-49 - - - S - - - PIN domain
KOOLEIAC_01215 1.65e-31 - - - K - - - Antidote-toxin recognition MazE, bacterial antitoxin
KOOLEIAC_01216 1.86e-89 mgtC - - S ko:K07507 - ko00000,ko02000 MgtC family
KOOLEIAC_01217 9.04e-24 - - - T - - - Histidine kinase
KOOLEIAC_01219 1.11e-64 - - - K - - - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOOLEIAC_01220 1.8e-261 - - - G - - - Transporter major facilitator family protein
KOOLEIAC_01221 9.16e-103 - - - K - - - Bacterial regulatory proteins, tetR family
KOOLEIAC_01222 1.26e-307 - - - S - - - Protein of unknown function (DUF4038)
KOOLEIAC_01223 7.48e-256 - - - G ko:K03292 - ko00000 Psort location CytoplasmicMembrane, score 10.00
KOOLEIAC_01224 7.72e-57 - - - S - - - Nucleotidyltransferase domain
KOOLEIAC_01225 5.15e-91 - - - S - - - Nucleotidyltransferase substrate binding protein like
KOOLEIAC_01226 1.71e-73 - 3.2.1.4, 3.2.1.58 GH5,GH9 G ko:K01179,ko:K01210 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 5 (cellulase A) family
KOOLEIAC_01227 7.52e-85 - 3.2.1.4, 3.2.1.58 GH5,GH9 G ko:K01179,ko:K01210 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 5 (cellulase A) family
KOOLEIAC_01228 4.76e-47 - - - - - - - -
KOOLEIAC_01229 3.26e-94 - - - K - - - Bacterial regulatory proteins, tetR family
KOOLEIAC_01230 2.86e-206 - - - G - - - Major Facilitator Superfamily
KOOLEIAC_01231 2.21e-310 - - - S ko:K06978 - ko00000 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain
KOOLEIAC_01232 2.51e-142 - - - I - - - Hydrolase, alpha beta domain protein
KOOLEIAC_01233 2.06e-112 - - - K - - - Bacterial regulatory proteins, tetR family
KOOLEIAC_01234 0.0 bglB 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
KOOLEIAC_01235 1.23e-117 - - - K - - - MarR family
KOOLEIAC_01236 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
KOOLEIAC_01237 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
KOOLEIAC_01238 0.0 - 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KOOLEIAC_01239 6.76e-137 - - - T ko:K16923 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
KOOLEIAC_01240 3.64e-181 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KOOLEIAC_01241 1.1e-194 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_01242 4.51e-196 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_01243 1.33e-153 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 N-(5'phosphoribosyl)anthranilate (PRA) isomerase
KOOLEIAC_01244 2.9e-227 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
KOOLEIAC_01245 1.16e-242 rihB 3.2.2.1, 3.2.2.8 - F ko:K01239,ko:K01250,ko:K10213 ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
KOOLEIAC_01246 1.77e-167 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KOOLEIAC_01247 6.53e-291 bdhA - - C ko:K19955 - ko00000,ko01000 Iron-containing alcohol dehydrogenase
KOOLEIAC_01248 8.14e-209 rbsK 2.7.1.15 - G ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KOOLEIAC_01249 0.0 - - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 Major Facilitator Superfamily
KOOLEIAC_01250 2.36e-48 - - - L ko:K07485 - ko00000 Transposase
KOOLEIAC_01251 2.61e-236 rbsR - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KOOLEIAC_01252 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_01253 3.48e-210 rbsC - - U ko:K10439,ko:K10440 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
KOOLEIAC_01254 3.38e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
KOOLEIAC_01255 7.09e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 RbsD / FucU transport protein family
KOOLEIAC_01256 5.62e-228 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KOOLEIAC_01257 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KOOLEIAC_01258 2.57e-15 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
KOOLEIAC_01259 2.33e-73 - - - K - - - Putative DNA-binding domain
KOOLEIAC_01260 1.74e-53 - - - K - - - Putative DNA-binding domain
KOOLEIAC_01261 9.04e-151 - - - K - - - Putative DNA-binding domain
KOOLEIAC_01262 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
KOOLEIAC_01263 1.33e-188 - - - G - - - Fic/DOC family
KOOLEIAC_01264 2.89e-292 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KOOLEIAC_01265 5.45e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KOOLEIAC_01266 0.0 ilvD 4.2.1.9 - H ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
KOOLEIAC_01267 5.26e-235 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KOOLEIAC_01268 8.38e-169 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KOOLEIAC_01269 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KOOLEIAC_01270 3.37e-153 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 haloacid dehalogenase-like hydrolase
KOOLEIAC_01271 2.05e-163 - - - S - - - SNARE associated Golgi protein
KOOLEIAC_01272 0.0 arc - - O ko:K13527 ko03050,map03050 ko00000,ko00001,ko00002,ko03051 AAA ATPase forming ring-shaped complexes
KOOLEIAC_01273 3.42e-174 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KOOLEIAC_01274 0.0 - - - K ko:K02538,ko:K03483,ko:K03491 - ko00000,ko03000 PRD domain
KOOLEIAC_01275 1.55e-94 - - - H - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KOOLEIAC_01276 1.9e-104 - 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KOOLEIAC_01277 2.2e-62 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KOOLEIAC_01278 2.06e-229 - - - G ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase System
KOOLEIAC_01279 6.14e-173 - - - G ko:K17195 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Ribulose-phosphate 3 epimerase family
KOOLEIAC_01280 0.0 dop 3.5.1.119 - S ko:K20814 - ko00000,ko01000,ko03051 Pup-ligase protein
KOOLEIAC_01281 4.8e-224 - 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase family
KOOLEIAC_01282 8.43e-16 pup - - S ko:K13570 - ko00000,ko04121 Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
KOOLEIAC_01283 0.0 pafA 6.3.1.19 - O ko:K13571 - ko00000,ko00002,ko01000,ko03051 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KOOLEIAC_01284 3.31e-57 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
KOOLEIAC_01285 0.0 - - - S - - - Lysylphosphatidylglycerol synthase TM region
KOOLEIAC_01286 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminal
KOOLEIAC_01287 3.68e-144 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
KOOLEIAC_01288 0.0 - - - S - - - PGAP1-like protein
KOOLEIAC_01289 8.64e-76 - - - - - - - -
KOOLEIAC_01290 1.27e-214 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
KOOLEIAC_01291 9.16e-241 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
KOOLEIAC_01292 3.26e-119 - - - - - - - -
KOOLEIAC_01293 3.97e-210 - - - S - - - Protein of unknown function DUF58
KOOLEIAC_01294 9.23e-247 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
KOOLEIAC_01295 8.09e-169 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KOOLEIAC_01296 3.14e-115 - - - S - - - LytR cell envelope-related transcriptional attenuator
KOOLEIAC_01297 1.54e-51 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
KOOLEIAC_01298 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KOOLEIAC_01299 6.57e-54 - - - S - - - Proteins of 100 residues with WXG
KOOLEIAC_01300 3.1e-147 - - - - - - - -
KOOLEIAC_01301 1.23e-170 phoP - - KT ko:K02483 - ko00000,ko02022 Response regulator receiver domain protein
KOOLEIAC_01302 0.0 phoR 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
KOOLEIAC_01303 7.13e-87 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
KOOLEIAC_01304 4.74e-244 - - - S - - - Protein of unknown function (DUF3027)
KOOLEIAC_01305 3.99e-231 uspA - - T - - - Belongs to the universal stress protein A family
KOOLEIAC_01306 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
KOOLEIAC_01307 2.13e-15 - - - K - - - AraC-like ligand binding domain
KOOLEIAC_01308 1.87e-176 gtr - - U ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Sugar (and other) transporter
KOOLEIAC_01309 1.66e-67 - - - I - - - Hydrolase, alpha beta domain protein
KOOLEIAC_01310 0.0 - 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
KOOLEIAC_01311 0.0 - - - S - - - Domain of Unknown Function (DUF349)
KOOLEIAC_01312 0.0 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Histidyl-tRNA synthetase
KOOLEIAC_01313 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KOOLEIAC_01314 5.61e-09 - - - S - - - Aminoacyl-tRNA editing domain
KOOLEIAC_01315 9.45e-198 gluA - - E ko:K10008 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding protein of ABC transporter for glutamate K02028
KOOLEIAC_01316 3.16e-189 gluB - - ET ko:K10005 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
KOOLEIAC_01317 1.21e-143 gluC - - E ko:K10006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01318 2.11e-251 gluD - - E ko:K10007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01319 0.0 - - - I - - - PAP2 superfamily
KOOLEIAC_01320 1.88e-144 - - - S ko:K06895 - ko00000,ko02000 LysE type translocator
KOOLEIAC_01321 0.0 - - - EK ko:K05825,ko:K18907 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko00002,ko01000,ko01504,ko03000 Alanine-glyoxylate amino-transferase
KOOLEIAC_01323 7.29e-255 - - - S - - - Polyphosphate kinase 2 (PPK2)
KOOLEIAC_01324 0.0 - - - L - - - DEAD DEAH box helicase
KOOLEIAC_01325 0.0 rarA - - L ko:K07478 - ko00000 Recombination factor protein RarA
KOOLEIAC_01326 1.81e-14 mtrA - - KT ko:K07670 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
KOOLEIAC_01327 9.99e-27 mtrB 2.7.13.3 - T ko:K07636,ko:K07654 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KOOLEIAC_01328 0.0 - - - EGP - - - Major Facilitator Superfamily
KOOLEIAC_01329 4.03e-239 - - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KOOLEIAC_01330 3.36e-69 - - - - - - - -
KOOLEIAC_01331 1.66e-70 - - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
KOOLEIAC_01332 4.67e-63 - - - J ko:K07574 - ko00000,ko03009 CRS1_YhbY
KOOLEIAC_01333 0.0 - - - GP ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KOOLEIAC_01334 4.04e-134 - - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KOOLEIAC_01335 1.55e-252 - - - S - - - Glycosyltransferase, group 2 family protein
KOOLEIAC_01336 3.43e-188 - - - C - - - Putative TM nitroreductase
KOOLEIAC_01337 6.61e-181 ppgK 2.7.1.2, 2.7.1.63 - GK ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KOOLEIAC_01338 0.0 fosC 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
KOOLEIAC_01339 1.8e-306 lacY - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
KOOLEIAC_01340 8.6e-250 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KOOLEIAC_01341 0.0 - - - O ko:K13963 ko05146,map05146 ko00000,ko00001 SERine Proteinase INhibitors
KOOLEIAC_01342 7.86e-242 - - - - - - - -
KOOLEIAC_01343 5.01e-159 - - - K - - - helix_turn_helix, Lux Regulon
KOOLEIAC_01344 1.13e-294 - - - T - - - Histidine kinase
KOOLEIAC_01345 0.0 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
KOOLEIAC_01346 1.64e-81 - - - S - - - Thiamine-binding protein
KOOLEIAC_01347 2.14e-187 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KOOLEIAC_01348 3.61e-286 - - - O ko:K13525 ko04141,ko05134,map04141,map05134 ko00000,ko00001,ko00002,ko03019,ko04131,ko04147 AAA domain (Cdc48 subfamily)
KOOLEIAC_01349 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KOOLEIAC_01350 5.53e-198 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KOOLEIAC_01351 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
KOOLEIAC_01352 1.01e-316 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KOOLEIAC_01353 8.65e-275 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KOOLEIAC_01354 2.98e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KOOLEIAC_01355 3.44e-60 - - - S ko:K02221 - ko00000,ko02044 YGGT family
KOOLEIAC_01356 1.2e-89 - - - V - - - DivIVA protein
KOOLEIAC_01357 1.72e-116 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KOOLEIAC_01358 4.29e-227 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KOOLEIAC_01359 1.23e-255 - - - K - - - WYL domain
KOOLEIAC_01360 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
KOOLEIAC_01362 2.55e-213 dkgV - - C - - - Aldo/keto reductase family
KOOLEIAC_01363 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
KOOLEIAC_01365 2.54e-161 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KOOLEIAC_01366 0.0 - 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
KOOLEIAC_01367 1.64e-57 csoR - - S ko:K21600 - ko00000,ko03000 Metal-sensitive transcriptional repressor
KOOLEIAC_01368 2.82e-271 rmuC - - S ko:K09760 - ko00000 RmuC family
KOOLEIAC_01369 1.15e-140 pyrE1 - - F - - - Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KOOLEIAC_01370 5.6e-199 trmH 2.1.1.34 - J ko:K00556 - ko00000,ko01000,ko03016 RNA methyltransferase TrmH family
KOOLEIAC_01371 9.14e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KOOLEIAC_01372 2.97e-226 - - - - - - - -
KOOLEIAC_01373 1.05e-63 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KOOLEIAC_01374 0.0 gatA 6.3.5.6, 6.3.5.7 - F ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KOOLEIAC_01375 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KOOLEIAC_01376 2.37e-248 - - - J - - - Acetyltransferase (GNAT) domain
KOOLEIAC_01377 2.66e-68 - - - S - - - Protein of unknown function (DUF2469)
KOOLEIAC_01378 0.0 - - - H - - - Flavin containing amine oxidoreductase
KOOLEIAC_01379 0.0 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KOOLEIAC_01380 1.15e-258 - - - K - - - helix_turn _helix lactose operon repressor
KOOLEIAC_01381 0.0 - - - G ko:K16139 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
KOOLEIAC_01382 0.0 lacZ3 - - G - - - Belongs to the glycosyl hydrolase 2 family
KOOLEIAC_01383 5.14e-78 - - - L - - - Transposase
KOOLEIAC_01384 2.19e-209 - - - L ko:K07493 - ko00000 PFAM Transposase, Mutator family
KOOLEIAC_01385 1.13e-192 - - - L ko:K03733 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
KOOLEIAC_01386 3.47e-63 - - - L ko:K07497 - ko00000 Integrase core domain
KOOLEIAC_01387 7.71e-82 tyrA 5.4.99.5 - E ko:K04092 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
KOOLEIAC_01388 0.0 - - - S - - - domain protein
KOOLEIAC_01389 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KOOLEIAC_01390 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
KOOLEIAC_01391 6.93e-162 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KOOLEIAC_01392 1.09e-178 glnR - - KT - - - Transcriptional regulatory protein, C terminal
KOOLEIAC_01393 7.63e-156 - - - - - - - -
KOOLEIAC_01394 2.74e-126 mntP - - P - - - Probably functions as a manganese efflux pump
KOOLEIAC_01395 1.95e-119 ppa 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KOOLEIAC_01396 0.0 glgE 2.4.99.16 GH13 G ko:K16147 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
KOOLEIAC_01397 0.0 - - - K - - - RNA polymerase II activating transcription factor binding
KOOLEIAC_01399 8.61e-264 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KOOLEIAC_01400 1.76e-192 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KOOLEIAC_01401 1.65e-40 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KOOLEIAC_01402 5.2e-103 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KOOLEIAC_01403 4.49e-195 atpH - - C ko:K02109,ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KOOLEIAC_01404 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KOOLEIAC_01405 1.2e-209 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KOOLEIAC_01406 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KOOLEIAC_01407 3.62e-65 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
KOOLEIAC_01408 3.01e-166 nucS - - L ko:K07503 - ko00000,ko01000 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
KOOLEIAC_01409 1.99e-213 - 5.2.1.8 - M ko:K01802 - ko00000,ko01000 FKBP-type peptidyl-prolyl cis-trans isomerase
KOOLEIAC_01410 3.89e-245 - - - - - - - -
KOOLEIAC_01411 2.31e-232 - - - - - - - -
KOOLEIAC_01412 5.98e-218 ybbN - - O ko:K05838 - ko00000,ko03110 Tetratricopeptide repeat
KOOLEIAC_01413 9.16e-151 - - - S - - - CYTH
KOOLEIAC_01416 3.27e-83 psp1 3.5.99.10 - J ko:K09022 - ko00000,ko01000 Endoribonuclease L-PSP
KOOLEIAC_01417 1.78e-241 plsC2 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
KOOLEIAC_01418 2.29e-227 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
KOOLEIAC_01419 1.17e-290 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KOOLEIAC_01420 1.01e-276 - - - P ko:K02055 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_01421 4.85e-207 - - - U ko:K02054 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01422 1.18e-198 - - - U ko:K02053 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01423 2.26e-303 - - - E ko:K02052 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KOOLEIAC_01424 7.19e-237 - - - S - - - CAAX protease self-immunity
KOOLEIAC_01425 6.51e-176 - - - M - - - Mechanosensitive ion channel
KOOLEIAC_01426 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
KOOLEIAC_01427 1.21e-15 - - - L - - - Transposase DDE domain
KOOLEIAC_01428 1.41e-172 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
KOOLEIAC_01429 0.0 - - - C ko:K06871 - ko00000 Iron-sulfur cluster-binding domain
KOOLEIAC_01430 3.49e-248 - - - K - - - helix_turn _helix lactose operon repressor
KOOLEIAC_01431 0.0 - - - P - - - Domain of unknown function (DUF4976)
KOOLEIAC_01432 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_01433 1.85e-211 - - - P ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01434 2.29e-227 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01435 6.3e-292 - - - S ko:K07133 - ko00000 AAA domain
KOOLEIAC_01436 2.54e-50 - - - L - - - Transposase, Mutator family
KOOLEIAC_01437 2.34e-135 - - - K - - - Bacterial regulatory proteins, tetR family
KOOLEIAC_01438 0.0 - - - S - - - Psort location Cytoplasmic, score 8.87
KOOLEIAC_01439 1.37e-115 ogt 2.1.1.63 - L ko:K00567,ko:K07443 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KOOLEIAC_01440 6.4e-106 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KOOLEIAC_01441 1.77e-92 ams 2.4.1.4 GH13 G ko:K05341 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
KOOLEIAC_01442 5.29e-146 - - - P - - - Sodium/hydrogen exchanger family
KOOLEIAC_01444 4.77e-143 - - - - - - - -
KOOLEIAC_01445 0.0 - - - M - - - Conserved repeat domain
KOOLEIAC_01446 0.0 - - - M - - - LPXTG cell wall anchor motif
KOOLEIAC_01448 3.09e-66 - - - - - - - -
KOOLEIAC_01450 5.54e-146 - - - - - - - -
KOOLEIAC_01451 2.04e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KOOLEIAC_01452 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KOOLEIAC_01453 1.35e-150 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KOOLEIAC_01454 1.19e-107 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KOOLEIAC_01455 7.13e-119 lemA - - S ko:K03744 - ko00000 LemA family
KOOLEIAC_01456 0.0 - - - S - - - Predicted membrane protein (DUF2207)
KOOLEIAC_01457 5.76e-14 - - - S - - - Predicted membrane protein (DUF2207)
KOOLEIAC_01458 7.23e-307 - - - S - - - Predicted membrane protein (DUF2207)
KOOLEIAC_01459 4.08e-28 - - - - - - - -
KOOLEIAC_01460 5.57e-214 - - - C - - - Oxidoreductase, aldo keto reductase family protein
KOOLEIAC_01461 6.38e-259 - 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
KOOLEIAC_01462 5.15e-138 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KOOLEIAC_01463 3.56e-47 - - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
KOOLEIAC_01464 9.48e-85 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
KOOLEIAC_01465 1.22e-266 - - - S - - - Endonuclease/Exonuclease/phosphatase family
KOOLEIAC_01466 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KOOLEIAC_01467 7.81e-208 - - - P - - - Cation efflux family
KOOLEIAC_01468 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KOOLEIAC_01469 2.8e-171 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase C26
KOOLEIAC_01470 0.0 yjjK - - S ko:K15738 - ko00000,ko02000 ABC transporter
KOOLEIAC_01471 8.06e-96 vapC - - S ko:K07062 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module. An RNase
KOOLEIAC_01472 1.52e-57 - - - S ko:K21495 - ko00000,ko02048 Plasmid stability protein
KOOLEIAC_01473 8.22e-120 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
KOOLEIAC_01474 0.0 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
KOOLEIAC_01475 6.09e-173 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KOOLEIAC_01476 4.87e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
KOOLEIAC_01477 3.89e-151 - - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
KOOLEIAC_01478 3.24e-159 - - - - - - - -
KOOLEIAC_01479 9.97e-114 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KOOLEIAC_01480 1.79e-65 - - - S - - - Protein of unknown function (DUF3039)
KOOLEIAC_01481 1.27e-235 - - - F ko:K10974 - ko00000,ko02000 Permease for cytosine/purines, uracil, thiamine, allantoin
KOOLEIAC_01482 2.84e-132 - - - S - - - Carbon-nitrogen hydrolase
KOOLEIAC_01483 2.27e-147 - - - F ko:K10974 - ko00000,ko02000 Permease for cytosine/purines, uracil, thiamine, allantoin
KOOLEIAC_01484 1.52e-110 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
KOOLEIAC_01485 1.58e-179 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
KOOLEIAC_01486 1.54e-268 - - - EQ - - - Hydantoinase/oxoprolinase N-terminal region
KOOLEIAC_01487 3.59e-165 - - - S - - - Protein of unknown function (DUF1177)
KOOLEIAC_01488 8.9e-247 - - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
KOOLEIAC_01489 7.41e-102 - - - K - - - MerR, DNA binding
KOOLEIAC_01490 1.41e-154 - - - - - - - -
KOOLEIAC_01491 1.4e-314 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KOOLEIAC_01492 3.84e-186 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KOOLEIAC_01493 3.52e-177 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KOOLEIAC_01494 7.64e-226 - - - S ko:K07088 - ko00000 Auxin Efflux Carrier
KOOLEIAC_01497 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
KOOLEIAC_01498 0.0 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_01499 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01501 9.65e-79 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KOOLEIAC_01502 9.32e-223 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KOOLEIAC_01503 4.53e-203 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KOOLEIAC_01504 8.26e-272 - - - K - - - helix_turn _helix lactose operon repressor
KOOLEIAC_01505 0.0 fadD 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
KOOLEIAC_01506 2.56e-37 - - - K - - - DNA-templated transcription, initiation
KOOLEIAC_01507 9.9e-116 XK26_06155 - - K - - - Psort location Cytoplasmic, score
KOOLEIAC_01508 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
KOOLEIAC_01509 4.04e-86 - - - S - - - Psort location Cytoplasmic, score 8.87
KOOLEIAC_01510 1.28e-48 - - - U ko:K02100 - ko00000,ko02000 Sugar (and other) transporter
KOOLEIAC_01511 6.18e-29 - - - U ko:K02100 - ko00000,ko02000 Sugar (and other) transporter
KOOLEIAC_01512 0.0 - - - V ko:K06147,ko:K06148,ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
KOOLEIAC_01513 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_01514 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
KOOLEIAC_01515 3.19e-232 - - - K - - - helix_turn _helix lactose operon repressor
KOOLEIAC_01516 0.0 galA 3.2.1.89 - G ko:K01224 - ko00000,ko01000 Glycosyl hydrolase family 53
KOOLEIAC_01518 1.47e-210 - - - S - - - Oxidoreductase, aldo keto reductase family protein
KOOLEIAC_01519 1.5e-180 - - - L - - - Protein of unknown function (DUF1524)
KOOLEIAC_01520 1.93e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
KOOLEIAC_01521 0.0 - - - U - - - Drug resistance MFS transporter, drug H antiporter-2 family
KOOLEIAC_01522 0.0 - - - H - - - Protein of unknown function (DUF4012)
KOOLEIAC_01523 2.51e-292 rfbP - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KOOLEIAC_01524 6.21e-141 etp 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Low molecular weight phosphatase family
KOOLEIAC_01525 7.51e-139 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
KOOLEIAC_01527 3.71e-185 - - - L - - - Transposase and inactivated derivatives IS30 family
KOOLEIAC_01528 6.11e-40 - - - L - - - Transposase and inactivated derivatives IS30 family
KOOLEIAC_01529 1.83e-175 - - - M - - - Psort location Cytoplasmic, score 8.87
KOOLEIAC_01530 2.93e-58 - - - M - - - Glycosyltransferase, group 1 family protein
KOOLEIAC_01532 1.99e-76 - - - C - - - Polysaccharide pyruvyl transferase
KOOLEIAC_01533 3.95e-143 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
KOOLEIAC_01534 2.48e-56 XK27_01805 - - M - - - Glycosyltransferase like family 2
KOOLEIAC_01535 2.34e-218 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
KOOLEIAC_01536 0.0 dppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
KOOLEIAC_01537 3.78e-112 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 peptide-methionine (S)-S-oxide reductase activity
KOOLEIAC_01538 6.56e-184 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_01539 1.11e-249 - - - M - - - Conserved repeat domain
KOOLEIAC_01540 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
KOOLEIAC_01541 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KOOLEIAC_01542 3.27e-230 yogA - - C - - - Zinc-binding dehydrogenase
KOOLEIAC_01543 2.42e-110 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KOOLEIAC_01544 6.98e-286 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KOOLEIAC_01545 6.55e-93 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
KOOLEIAC_01546 9.03e-62 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
KOOLEIAC_01547 9.84e-85 - - - - - - - -
KOOLEIAC_01548 2.35e-112 fur - - P ko:K03711 - ko00000,ko03000 Ferric uptake regulator family
KOOLEIAC_01549 1.14e-179 - - - S - - - TIGRFAM TIGR03943 family protein
KOOLEIAC_01550 1.54e-237 - - - S ko:K07089 - ko00000 Predicted permease
KOOLEIAC_01551 1.27e-07 - - - P ko:K02077,ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
KOOLEIAC_01552 9.3e-35 - - - P ko:K02077,ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
KOOLEIAC_01553 1.55e-27 - - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Ribosomal L32p protein family
KOOLEIAC_01554 4.34e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L36
KOOLEIAC_01555 1.72e-45 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
KOOLEIAC_01556 2.5e-58 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KOOLEIAC_01557 5.79e-28 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
KOOLEIAC_01558 8.31e-40 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
KOOLEIAC_01559 1.13e-127 - - - S - - - cobalamin synthesis protein
KOOLEIAC_01560 4.68e-207 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
KOOLEIAC_01561 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 9.26
KOOLEIAC_01562 0.0 aldH 1.2.1.3, 1.2.99.10 - C ko:K00128,ko:K22445 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldehyde dehydrogenase family
KOOLEIAC_01563 1e-307 purD 6.3.3.1, 6.3.4.13 - F ko:K01945,ko:K11788 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
KOOLEIAC_01564 1.84e-239 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
KOOLEIAC_01565 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KOOLEIAC_01566 0.0 - - - L ko:K03502 - ko00000,ko03400 DNA-damage repair protein (DNA polymerase IV) K00961
KOOLEIAC_01567 1.4e-44 - - - - - - - -
KOOLEIAC_01568 2.77e-17 - - - C - - - Aldo/keto reductase family
KOOLEIAC_01569 2.67e-132 nnrE - - L - - - Uracil DNA glycosylase superfamily
KOOLEIAC_01573 6.15e-40 - - - S - - - Protein of unknown function (DUF4230)
KOOLEIAC_01574 8.33e-187 - - - - - - - -
KOOLEIAC_01575 1.96e-146 - - - Q - - - D-alanine [D-alanyl carrier protein] ligase activity
KOOLEIAC_01576 0.0 - - - Q - - - D-alanine [D-alanyl carrier protein] ligase activity
KOOLEIAC_01577 2.4e-313 - - - I - - - alpha/beta hydrolase fold
KOOLEIAC_01578 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 CobB/CobQ-like glutamine amidotransferase domain
KOOLEIAC_01579 4.83e-176 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
KOOLEIAC_01580 1.01e-292 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KOOLEIAC_01581 3e-290 - 2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83 - E ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261 ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
KOOLEIAC_01582 1.29e-278 - - - M - - - Glycosyl transferase 4-like domain
KOOLEIAC_01583 1.74e-251 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Beta-eliminating lyase
KOOLEIAC_01585 4.61e-142 - - - S ko:K03453 - ko00000 SBF-like CPA transporter family (DUF4137)
KOOLEIAC_01586 5.77e-81 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KOOLEIAC_01587 1.9e-104 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KOOLEIAC_01588 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KOOLEIAC_01589 4.1e-293 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KOOLEIAC_01590 1.44e-146 tmp1 - - S - - - Domain of unknown function (DUF4391)
KOOLEIAC_01591 6.07e-185 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
KOOLEIAC_01592 2.5e-237 - - - S - - - Conserved hypothetical protein 698
KOOLEIAC_01594 2.64e-41 - - - S - - - Psort location CytoplasmicMembrane, score
KOOLEIAC_01595 9.65e-79 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KOOLEIAC_01596 1.74e-113 - - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KOOLEIAC_01597 8.54e-24 - - - K - - - MerR family regulatory protein
KOOLEIAC_01598 2.34e-21 - - - K - - - MerR family regulatory protein
KOOLEIAC_01599 1.21e-245 adh 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
KOOLEIAC_01600 0.0 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
KOOLEIAC_01601 1.52e-45 - - - - - - - -
KOOLEIAC_01602 9.68e-99 - - - KT - - - Transcriptional regulatory protein, C terminal
KOOLEIAC_01603 3.63e-213 - 3.1.1.53 - E ko:K05970 - ko00000,ko01000 Carbohydrate esterase, sialic acid-specific acetylesterase
KOOLEIAC_01604 6.01e-186 - - - E - - - GDSL-like Lipase/Acylhydrolase family
KOOLEIAC_01605 2.13e-297 bglA 3.2.1.21 - G ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
KOOLEIAC_01606 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
KOOLEIAC_01607 1.08e-223 - - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01608 1.05e-197 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01609 4.19e-173 - - - EP ko:K02031,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
KOOLEIAC_01610 3.59e-178 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
KOOLEIAC_01611 0.0 - 3.2.1.25 - G ko:K01192 ko00511,ko04142,map00511,map04142 ko00000,ko00001,ko01000 beta-mannosidase
KOOLEIAC_01612 2.11e-178 - - - K - - - helix_turn _helix lactose operon repressor
KOOLEIAC_01614 1.23e-276 - - - G - - - N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KOOLEIAC_01615 2.98e-196 - - - K - - - LysR substrate binding domain
KOOLEIAC_01616 1.44e-287 - - - EGP - - - Major Facilitator Superfamily
KOOLEIAC_01617 1.33e-176 - - - K - - - LysR substrate binding domain
KOOLEIAC_01618 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KOOLEIAC_01619 8.03e-311 - - - V - - - MatE
KOOLEIAC_01620 4.44e-159 - - - L ko:K07457 - ko00000 endonuclease III
KOOLEIAC_01621 1e-148 - 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
KOOLEIAC_01622 7.38e-50 - 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
KOOLEIAC_01623 8.37e-237 - - - S ko:K07088 - ko00000 Membrane transport protein
KOOLEIAC_01624 4.23e-63 - 4.1.1.44 - L ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
KOOLEIAC_01626 0.0 - - - M - - - probably involved in cell wall
KOOLEIAC_01627 0.0 - 3.2.1.14 GH18 S ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Carbohydrate binding domain
KOOLEIAC_01628 0.0 - - - T - - - Diguanylate cyclase, GGDEF domain
KOOLEIAC_01629 2.46e-175 - - - V ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
KOOLEIAC_01630 3.67e-164 - - - V ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_01631 6.57e-136 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KOOLEIAC_01632 3.41e-119 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KOOLEIAC_01633 1.78e-307 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
KOOLEIAC_01634 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase large chain, oligomerisation domain
KOOLEIAC_01635 2.65e-217 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KOOLEIAC_01636 9.2e-136 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KOOLEIAC_01637 2.93e-174 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Exonuclease, DNA polymerase III, epsilon subunit family
KOOLEIAC_01638 1.98e-06 - - - - - - - -
KOOLEIAC_01639 0.0 tetM - - J ko:K18220 - br01600,ko00000,ko01504 Elongation factor G, domain IV
KOOLEIAC_01640 1.31e-160 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
KOOLEIAC_01641 6.38e-298 metC1 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
KOOLEIAC_01642 1.32e-56 - - - O - - - Glutaredoxin
KOOLEIAC_01643 2.13e-222 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
KOOLEIAC_01644 1.41e-11 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
KOOLEIAC_01645 1.03e-169 hflK - - O - - - prohibitin homologues
KOOLEIAC_01646 2.83e-255 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
KOOLEIAC_01647 8.15e-204 - - - S - - - Patatin-like phospholipase
KOOLEIAC_01648 5.69e-191 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KOOLEIAC_01649 4.41e-217 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
KOOLEIAC_01650 3.96e-165 - - - S - - - Vitamin K epoxide reductase
KOOLEIAC_01651 1.8e-215 PPA1328 3.1.3.97, 3.1.4.57 - S ko:K07053,ko:K20859 ko00440,map00440 ko00000,ko00001,ko01000 DNA polymerase alpha chain like domain
KOOLEIAC_01652 3.25e-44 - - - S - - - Protein of unknown function (DUF3107)
KOOLEIAC_01653 0.0 mphA - - S - - - Aminoglycoside phosphotransferase
KOOLEIAC_01654 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KOOLEIAC_01655 0.0 - - - S - - - Zincin-like metallopeptidase
KOOLEIAC_01656 2.21e-212 sdrC - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KOOLEIAC_01657 2.42e-96 - - - S - - - Protein of unknown function (DUF3052)
KOOLEIAC_01659 8.77e-298 - - - NU - - - Tfp pilus assembly protein FimV
KOOLEIAC_01660 2.93e-280 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KOOLEIAC_01661 6.58e-294 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KOOLEIAC_01662 0.0 - - - I - - - acetylesterase activity
KOOLEIAC_01663 6.84e-166 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
KOOLEIAC_01664 1.58e-197 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 - H ko:K00806,ko:K14215,ko:K21273 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KOOLEIAC_01665 2.46e-173 - - - P - - - Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01666 1.25e-242 - - - P - - - NMT1/THI5 like
KOOLEIAC_01667 8.76e-281 - - - E - - - Aminotransferase class I and II
KOOLEIAC_01668 5.62e-182 - - - P ko:K16784 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_01669 8.79e-09 - 2.8.2.22 - S ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
KOOLEIAC_01670 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KOOLEIAC_01671 0.0 - - - S - - - Tetratricopeptide repeat
KOOLEIAC_01672 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KOOLEIAC_01673 3.32e-263 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KOOLEIAC_01674 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KOOLEIAC_01675 4.13e-182 - - - S - - - Domain of unknown function (DUF4191)
KOOLEIAC_01676 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KOOLEIAC_01677 4.43e-130 - - - S - - - Protein of unknown function (DUF3043)
KOOLEIAC_01678 0.0 argE - - E - - - Peptidase dimerisation domain
KOOLEIAC_01679 3.75e-141 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
KOOLEIAC_01680 0.0 ykoD - - P ko:K16785,ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_01681 7.5e-211 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KOOLEIAC_01682 4.02e-205 tsnR - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KOOLEIAC_01683 4.35e-258 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KOOLEIAC_01684 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Phenylalanyl-tRNA synthetase beta
KOOLEIAC_01685 5.13e-137 - - - - - - - -
KOOLEIAC_01686 5.47e-258 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KOOLEIAC_01687 9.26e-270 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KOOLEIAC_01688 2.29e-224 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
KOOLEIAC_01689 3.98e-314 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
KOOLEIAC_01690 7.19e-234 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KOOLEIAC_01691 1.24e-109 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
KOOLEIAC_01692 1.2e-303 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
KOOLEIAC_01693 1.87e-26 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_01694 8.09e-62 - - - L - - - PFAM Integrase catalytic
KOOLEIAC_01695 5.68e-40 - - - L - - - PFAM Integrase catalytic
KOOLEIAC_01697 0.0 - - - L - - - PFAM Integrase catalytic
KOOLEIAC_01698 3.52e-12 - - - - - - - -
KOOLEIAC_01700 1.25e-13 - - - L - - - HTH-like domain
KOOLEIAC_01701 2.78e-27 - - - L - - - PFAM Integrase catalytic
KOOLEIAC_01702 2.75e-108 - - - - - - - -
KOOLEIAC_01703 1.12e-86 - - - - - - - -
KOOLEIAC_01704 1.1e-70 - - - L - - - Transposase, Mutator family
KOOLEIAC_01705 4.75e-109 - - - L - - - Transposase, Mutator family
KOOLEIAC_01706 1.49e-176 - - - L - - - IstB-like ATP binding protein
KOOLEIAC_01707 7.82e-295 - - - L - - - PFAM Integrase catalytic
KOOLEIAC_01708 6.31e-25 - - - S - - - AAA ATPase domain
KOOLEIAC_01709 6.93e-127 - - - K - - - Transposase IS116 IS110 IS902
KOOLEIAC_01710 3.97e-12 - - - L - - - Transposase and inactivated derivatives IS30 family
KOOLEIAC_01711 0.0 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
KOOLEIAC_01712 8.26e-91 - - - - - - - -
KOOLEIAC_01713 2.7e-313 wcoI - - DM - - - Psort location CytoplasmicMembrane, score
KOOLEIAC_01714 9.96e-273 - - - - - - - -
KOOLEIAC_01715 2.85e-218 - - - S ko:K21688 - ko00000 G5
KOOLEIAC_01716 5.55e-79 trxA 1.8.1.9 - O ko:K00384,ko:K03671 ko00450,ko04621,ko05418,map00450,map04621,map05418 ko00000,ko00001,ko01000,ko03110 Belongs to the thioredoxin family
KOOLEIAC_01717 7.47e-156 - - - F - - - Domain of unknown function (DUF4916)
KOOLEIAC_01718 1.64e-203 - - - I - - - Alpha/beta hydrolase family
KOOLEIAC_01719 8.81e-284 nudC 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
KOOLEIAC_01720 1.48e-90 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
KOOLEIAC_01721 5.76e-284 - - - S - - - Uncharacterized conserved protein (DUF2183)
KOOLEIAC_01722 0.0 ptrB 3.4.21.83 - E ko:K01354 ko05142,ko05143,map05142,map05143 ko00000,ko00001,ko01000,ko01002 Peptidase, S9A B C family, catalytic domain protein
KOOLEIAC_01723 5.14e-245 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KOOLEIAC_01724 7.91e-278 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
KOOLEIAC_01725 2.7e-172 crp - - K ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
KOOLEIAC_01726 0.0 pon1 - - M - - - Transglycosylase
KOOLEIAC_01727 1.73e-305 namA - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
KOOLEIAC_01728 3.6e-288 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
KOOLEIAC_01729 3.61e-158 - - - K - - - DeoR C terminal sensor domain
KOOLEIAC_01730 0.0 galT 2.7.7.12 - C ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 Galactose-1-phosphate uridyl transferase, N-terminal domain
KOOLEIAC_01731 6.15e-299 galK 2.7.1.6, 2.7.7.12 - G ko:K00849,ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family. GalK subfamily
KOOLEIAC_01732 7.93e-59 - - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
KOOLEIAC_01733 0.0 - - - S ko:K09157 - ko00000 UPF0210 protein
KOOLEIAC_01735 3.37e-148 spoU 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KOOLEIAC_01736 4.88e-236 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 FES
KOOLEIAC_01737 3.82e-166 - - - - - - - -
KOOLEIAC_01738 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOOLEIAC_01739 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOOLEIAC_01740 0.0 - - - E - - - Transglutaminase-like superfamily
KOOLEIAC_01741 5.59e-309 - - - S - - - Protein of unknown function DUF58
KOOLEIAC_01742 0.0 - - - S - - - Fibronectin type 3 domain
KOOLEIAC_01743 2.51e-283 pknK 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
KOOLEIAC_01744 0.0 - - - L - - - PD-(D/E)XK nuclease superfamily
KOOLEIAC_01745 0.0 uvrD2 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 Belongs to the helicase family. UvrD subfamily
KOOLEIAC_01746 2.73e-300 - - - G - - - Major Facilitator Superfamily
KOOLEIAC_01747 2.77e-171 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KOOLEIAC_01748 2.06e-208 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KOOLEIAC_01749 0.0 rnj - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KOOLEIAC_01750 0.0 pepN 3.4.11.2 - E ko:K01256,ko:K08776 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Peptidase family M1 domain
KOOLEIAC_01751 1e-65 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
KOOLEIAC_01753 4.76e-131 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_01754 2.14e-138 - - - P ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01755 9.22e-148 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01756 8.08e-164 - 3.2.1.21 - G ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 1
KOOLEIAC_01757 5.35e-30 - - - K - - - AraC-like ligand binding domain
KOOLEIAC_01758 1.31e-74 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
KOOLEIAC_01759 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KOOLEIAC_01760 8.77e-158 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KOOLEIAC_01761 0.0 - - - L - - - Psort location Cytoplasmic, score
KOOLEIAC_01762 2.52e-263 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KOOLEIAC_01763 1.86e-268 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Cell division ATP-binding protein FtsE
KOOLEIAC_01764 1.9e-206 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in cellular division
KOOLEIAC_01765 2.74e-207 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain protein
KOOLEIAC_01766 1.33e-105 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KOOLEIAC_01767 6.96e-198 glnH - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter, substrate-binding protein, family 3
KOOLEIAC_01768 3.75e-216 glnH - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter, substrate-binding protein, family 3
KOOLEIAC_01769 1.54e-222 yecS - - E ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01770 3.69e-193 tcyC 3.6.3.21 - E ko:K02028,ko:K02029 - ko00000,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_01771 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KOOLEIAC_01772 1.77e-180 - 5.4.99.28, 5.4.99.29 - J ko:K06177 - ko00000,ko01000,ko03009,ko03016 RNA pseudouridylate synthase
KOOLEIAC_01773 9.16e-240 - - - K - - - Periplasmic binding protein domain
KOOLEIAC_01774 1.79e-216 - - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01775 2.47e-226 - - - G ko:K02026 - ko00000,ko00002,ko02000 ABC transporter permease
KOOLEIAC_01776 0.0 bga1 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
KOOLEIAC_01777 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_01778 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_01779 4.49e-184 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KOOLEIAC_01780 0.0 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
KOOLEIAC_01781 7.47e-213 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01782 1.33e-196 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01783 2.27e-176 - - - EP ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 oligopeptide transport protein of the ABC superfamily, ATP-binding component
KOOLEIAC_01784 3.37e-177 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_01785 1.42e-245 cbs 2.5.1.47, 4.2.1.22 - E ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
KOOLEIAC_01786 1.07e-281 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
KOOLEIAC_01787 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
KOOLEIAC_01788 2.77e-119 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KOOLEIAC_01789 2.22e-126 cysE - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KOOLEIAC_01790 2.84e-144 - - - K - - - helix_turn_helix, Deoxyribose operon repressor
KOOLEIAC_01791 4.48e-224 - - - G - - - Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
KOOLEIAC_01792 1.53e-302 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2264)
KOOLEIAC_01793 0.0 - 3.2.1.45 GH30 G ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 TIM-barrel domain
KOOLEIAC_01794 2.39e-201 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_01795 1.19e-169 - - - U ko:K02025,ko:K17242 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01796 2.24e-166 - - - U ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01797 7.48e-45 - - - - - - - -
KOOLEIAC_01798 0.0 - - - M - - - Belongs to the glycosyl hydrolase 30 family
KOOLEIAC_01799 1.12e-216 - - - G ko:K16210 - ko00000,ko02000 MFS/sugar transport protein
KOOLEIAC_01800 4.17e-294 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KOOLEIAC_01801 9.95e-82 gntK 2.7.1.12 - F ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Shikimate kinase
KOOLEIAC_01802 3.2e-295 - 4.2.1.8 - M ko:K08323 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 mandelate racemase muconate lactonizing
KOOLEIAC_01803 1.54e-244 mtlD 1.1.1.57, 1.1.1.58 - G ko:K00040,ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Mannitol dehydrogenase C-terminal domain
KOOLEIAC_01804 2.28e-223 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Glucuronate isomerase
KOOLEIAC_01805 5.9e-63 - - - FG - - - bis(5'-adenosyl)-triphosphatase activity
KOOLEIAC_01806 2.54e-91 - - - K ko:K02529,ko:K05499 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
KOOLEIAC_01807 4.91e-87 - - - K ko:K02529,ko:K05499 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
KOOLEIAC_01808 0.0 aap1 - - E ko:K03294 - ko00000 aromatic amino acid transport protein AroP K03293
KOOLEIAC_01809 0.0 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KOOLEIAC_01810 2.91e-310 dgt 3.1.5.1 - F ko:K01129 ko00230,map00230 ko00000,ko00001,ko01000 Phosphohydrolase-associated domain
KOOLEIAC_01811 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KOOLEIAC_01812 2.81e-200 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KOOLEIAC_01813 6.92e-148 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KOOLEIAC_01814 0.0 - - - EK ko:K03710,ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000,ko03000 Alanine-glyoxylate amino-transferase
KOOLEIAC_01815 1.36e-267 - - - P - - - Citrate transporter
KOOLEIAC_01816 9.8e-41 - - - - - - - -
KOOLEIAC_01817 4.89e-50 - - - G - - - Alpha-L-arabinofuranosidase C-terminal domain
KOOLEIAC_01818 2.25e-205 - - - K - - - Helix-turn-helix domain, rpiR family
KOOLEIAC_01821 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_01822 9.75e-295 - - - K - - - helix_turn _helix lactose operon repressor
KOOLEIAC_01823 0.0 - 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
KOOLEIAC_01824 3.62e-21 - - - L ko:K07483 - ko00000 Psort location Cytoplasmic, score 8.87
KOOLEIAC_01825 1.72e-94 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
KOOLEIAC_01826 2.15e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KOOLEIAC_01827 2.88e-109 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
KOOLEIAC_01828 2.77e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
KOOLEIAC_01829 3.31e-238 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KOOLEIAC_01830 2e-170 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KOOLEIAC_01831 1.29e-121 - 3.2.1.185 GH127 S ko:K09955,ko:K18205 - ko00000,ko01000 Beta-L-arabinofuranosidase, GH127
KOOLEIAC_01832 1.4e-200 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein domain
KOOLEIAC_01833 2.6e-175 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KOOLEIAC_01834 1.25e-255 - 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
KOOLEIAC_01835 0.0 - - - M - - - Protein of unknown function (DUF2961)
KOOLEIAC_01836 1.18e-162 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport systems inner membrane component
KOOLEIAC_01837 7.42e-159 - - - P ko:K02025,ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01838 9.58e-248 - - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_01839 8.5e-105 - - - L - - - Transposase
KOOLEIAC_01840 3.8e-12 - - - L - - - Transposase
KOOLEIAC_01841 0.0 - - - S ko:K03688 - ko00000 ABC1 family
KOOLEIAC_01842 1.1e-51 - - - S - - - granule-associated protein
KOOLEIAC_01843 6.12e-179 cobQ2 - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
KOOLEIAC_01844 0.0 murE - - M - - - Domain of unknown function (DUF1727)
KOOLEIAC_01845 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KOOLEIAC_01846 7.51e-299 dinF - - V - - - MatE
KOOLEIAC_01847 0.0 glnD 2.7.7.59 - O ko:K00990 ko02020,map02020 ko00000,ko00001,ko01000 Nucleotidyltransferase domain
KOOLEIAC_01848 1.27e-72 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Nitrogen regulatory protein P-II
KOOLEIAC_01849 1.12e-304 amt - - U ko:K03320 - ko00000,ko02000 Ammonium Transporter Family
KOOLEIAC_01850 1.45e-234 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KOOLEIAC_01851 4.13e-193 icaR - - K - - - Bacterial regulatory proteins, tetR family
KOOLEIAC_01852 4.44e-251 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 Glycosyltransferase like family 2
KOOLEIAC_01853 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
KOOLEIAC_01855 0.0 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
KOOLEIAC_01856 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KOOLEIAC_01857 1.73e-246 opcA - - G - - - Glucose-6-phosphate dehydrogenase subunit
KOOLEIAC_01858 3.85e-197 pgl 3.1.1.31 - G ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
KOOLEIAC_01859 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KOOLEIAC_01860 0.0 - - - S - - - Putative ABC-transporter type IV
KOOLEIAC_01861 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
KOOLEIAC_01862 0.0 - - - S ko:K01421 - ko00000 YhgE Pip domain protein
KOOLEIAC_01863 1.62e-130 - - - K - - - Psort location Cytoplasmic, score 8.87
KOOLEIAC_01864 1.68e-102 - - - S - - - FMN_bind
KOOLEIAC_01865 1.39e-187 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KOOLEIAC_01866 6.63e-277 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KOOLEIAC_01867 7.36e-291 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KOOLEIAC_01868 1.05e-293 - - - S - - - Predicted membrane protein (DUF2318)
KOOLEIAC_01869 1.89e-159 - - - P ko:K07230 - ko00000,ko02000 Fe2+ transport protein
KOOLEIAC_01870 0.0 - - - P ko:K07243 - ko00000,ko02000 Iron permease FTR1 family
KOOLEIAC_01872 1.62e-82 intA - - L - - - Phage integrase, N-terminal SAM-like domain
KOOLEIAC_01875 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KOOLEIAC_01877 9.23e-230 - - - S - - - Protein of unknown function (DUF805)
KOOLEIAC_01878 9.94e-287 - 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
KOOLEIAC_01879 3.35e-203 - - - - - - - -
KOOLEIAC_01880 4.52e-161 - - - G - - - Phosphoglycerate mutase family
KOOLEIAC_01881 0.0 - - - EGP - - - Major Facilitator Superfamily
KOOLEIAC_01882 1.29e-124 - - - S - - - GtrA-like protein
KOOLEIAC_01883 9.13e-81 - - - S - - - Macrophage migration inhibitory factor (MIF)
KOOLEIAC_01884 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formate-tetrahydrofolate ligase
KOOLEIAC_01885 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Peptidase family C69
KOOLEIAC_01886 3.14e-137 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
KOOLEIAC_01887 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KOOLEIAC_01889 1.47e-50 hpr - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
KOOLEIAC_01890 1.5e-136 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KOOLEIAC_01891 1.31e-265 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KOOLEIAC_01892 1.23e-151 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KOOLEIAC_01893 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KOOLEIAC_01894 2.73e-212 - - - I - - - PAP2 superfamily
KOOLEIAC_01895 0.0 pbp5 - - M - - - Transglycosylase
KOOLEIAC_01896 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KOOLEIAC_01897 0.0 - - - S - - - Calcineurin-like phosphoesterase
KOOLEIAC_01899 6.61e-195 - - - K - - - FCD
KOOLEIAC_01900 9.3e-307 - - - P ko:K07133 - ko00000 Domain of unknown function (DUF4143)
KOOLEIAC_01901 0.0 neu 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR repeat-like domain
KOOLEIAC_01902 3.53e-17 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Amidohydrolase family
KOOLEIAC_01903 3.69e-190 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KOOLEIAC_01904 2.23e-232 nanA 4.1.3.3, 4.3.3.7 - EM ko:K01639,ko:K01714 ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
KOOLEIAC_01905 2.91e-189 oppF - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_01906 0.0 oppCD2 - - EP ko:K02031,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
KOOLEIAC_01907 2.11e-204 oppB6 - - EP ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01908 0.0 oppA7 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
KOOLEIAC_01909 3.46e-205 - 3.5.1.106 - I ko:K15357 ko00760,ko01120,map00760,map01120 ko00000,ko00001,ko00002,ko01000 carboxylic ester hydrolase activity
KOOLEIAC_01910 1.2e-162 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KOOLEIAC_01911 1.01e-227 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KOOLEIAC_01912 1.22e-220 - - - L - - - Domain of unknown function (DUF4862)
KOOLEIAC_01913 1.64e-143 - - - - - - - -
KOOLEIAC_01914 1.94e-271 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KOOLEIAC_01915 2.87e-126 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
KOOLEIAC_01916 6.3e-174 ask 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
KOOLEIAC_01917 3.96e-225 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
KOOLEIAC_01918 3.03e-46 - - - V - - - Abi-like protein
KOOLEIAC_01919 3.21e-269 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
KOOLEIAC_01920 9.94e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KOOLEIAC_01921 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III subunit gamma tau
KOOLEIAC_01922 1.98e-127 - - - K - - - Bacterial regulatory proteins, tetR family
KOOLEIAC_01923 7.68e-275 - 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Diacylglycerol kinase catalytic domain protein
KOOLEIAC_01924 3.01e-70 - - - S - - - TIGRFAM helicase secretion neighborhood TadE-like protein
KOOLEIAC_01925 2.92e-75 - - - U - - - TadE-like protein
KOOLEIAC_01926 3.68e-55 - - - S - - - Protein of unknown function (DUF4244)
KOOLEIAC_01927 6.89e-151 - - - NU - - - Type II secretion system (T2SS), protein F
KOOLEIAC_01928 7.27e-95 - - - U ko:K12510 - ko00000,ko02044 Type ii secretion system
KOOLEIAC_01929 1.53e-244 cpaF - - U ko:K02283 - ko00000,ko02035,ko02044 Type II IV secretion system protein
KOOLEIAC_01930 3.05e-158 - - - D - - - bacterial-type flagellum organization
KOOLEIAC_01931 9.04e-172 dedA1 - - S ko:K03975 - ko00000 SNARE associated Golgi protein
KOOLEIAC_01932 2.23e-163 - - - S - - - HAD hydrolase, family IA, variant 3
KOOLEIAC_01933 5.31e-181 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
KOOLEIAC_01934 5.43e-21 - - - F - - - Psort location CytoplasmicMembrane, score 10.00
KOOLEIAC_01935 3.33e-133 hspR - - K ko:K13640 - ko00000,ko03000 transcriptional regulator, MerR family
KOOLEIAC_01936 2.35e-222 dnaJ - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 DnaJ molecular chaperone homology domain
KOOLEIAC_01937 2.49e-114 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KOOLEIAC_01938 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KOOLEIAC_01939 0.0 - 3.2.1.1, 3.2.1.41 CBM48,GH13 M ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 Aamy_C
KOOLEIAC_01940 1.6e-247 - - - K - - - Psort location Cytoplasmic, score
KOOLEIAC_01941 1.89e-186 traX - - S - - - TraX protein
KOOLEIAC_01942 1.08e-221 - - - S ko:K07025 - ko00000 HAD-hyrolase-like
KOOLEIAC_01943 0.0 apuB 3.2.1.41, 3.2.1.68 CBM48,GH13 G ko:K01200,ko:K01214 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 13 family
KOOLEIAC_01944 5.5e-210 malG - - G ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01945 0.0 malC - - G ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01946 1.15e-297 malE - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_01947 0.0 malL 2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16 GH13,GH31 G ko:K01187,ko:K05341,ko:K05343 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
KOOLEIAC_01948 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
KOOLEIAC_01949 2.65e-219 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
KOOLEIAC_01950 0.0 - - - M - - - domain protein
KOOLEIAC_01951 0.0 - - - M - - - cell wall anchor domain protein
KOOLEIAC_01952 2.24e-239 - - - K - - - Psort location Cytoplasmic, score
KOOLEIAC_01953 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
KOOLEIAC_01954 4.75e-245 - - - K - - - Transcriptional regulator
KOOLEIAC_01955 2.23e-187 - - - S - - - Psort location Cytoplasmic, score
KOOLEIAC_01956 1.76e-260 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KOOLEIAC_01957 7.18e-260 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KOOLEIAC_01958 2.49e-256 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
KOOLEIAC_01959 3.55e-23 - - - S - - - Haloacid dehalogenase-like hydrolase
KOOLEIAC_01960 1.12e-24 - - - K - - - Transcriptional regulator, rpir family
KOOLEIAC_01961 2.87e-145 - - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
KOOLEIAC_01962 8.45e-105 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KOOLEIAC_01963 1.03e-100 - - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01964 5.8e-105 ptxC - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_01965 1.1e-74 - - - F - - - Calcineurin-like phosphoesterase
KOOLEIAC_01966 7.4e-31 - - - L ko:K07485 - ko00000 Transposase
KOOLEIAC_01969 3.64e-252 - - - S - - - Psort location CytoplasmicMembrane, score
KOOLEIAC_01970 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
KOOLEIAC_01971 1.77e-261 - - - V - - - VanZ like family
KOOLEIAC_01972 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.87
KOOLEIAC_01973 2.06e-13 gph - - G ko:K16209 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
KOOLEIAC_01974 2.84e-239 - - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
KOOLEIAC_01975 6.05e-89 - - - S - - - Transmembrane domain of unknown function (DUF3566)
KOOLEIAC_01976 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KOOLEIAC_01977 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KOOLEIAC_01978 9.78e-107 - - - S - - - Protein of unknown function (DUF721)
KOOLEIAC_01979 2.17e-254 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KOOLEIAC_01980 4.88e-261 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KOOLEIAC_01981 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KOOLEIAC_01982 4.62e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
KOOLEIAC_01983 2.15e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KOOLEIAC_01984 2.94e-236 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
KOOLEIAC_01985 1.97e-119 jag - - S ko:K06346 - ko00000 Putative single-stranded nucleic acids-binding domain
KOOLEIAC_01986 5.06e-159 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
KOOLEIAC_01987 1.48e-222 parA - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
KOOLEIAC_01988 5.76e-286 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KOOLEIAC_01989 4.24e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KOOLEIAC_01990 0.0 mviN - - KLT ko:K03980 - ko00000,ko01011,ko02000 MviN-like protein
KOOLEIAC_01991 0.0 - - - - - - - -
KOOLEIAC_01992 5.27e-211 mutT4 - - L - - - Belongs to the Nudix hydrolase family
KOOLEIAC_01993 0.0 pcnA 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 Probable RNA and SrmB- binding site of polymerase A
KOOLEIAC_01994 4.16e-143 - - - S - - - LytR cell envelope-related transcriptional attenuator
KOOLEIAC_01995 1.28e-224 ispE 2.7.1.148 - F ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KOOLEIAC_01996 3.21e-215 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KOOLEIAC_01997 3.31e-279 rpfB - - S ko:K21688 - ko00000 G5
KOOLEIAC_01999 3.61e-181 - - - O - - - Thioredoxin
KOOLEIAC_02000 0.0 - - - KLT - - - Protein tyrosine kinase
KOOLEIAC_02001 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
KOOLEIAC_02002 5.08e-113 - - - T - - - LytTr DNA-binding domain
KOOLEIAC_02003 7.8e-156 - - - K - - - Helix-turn-helix XRE-family like proteins
KOOLEIAC_02004 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
KOOLEIAC_02005 6.17e-158 - - - S - - - Psort location CytoplasmicMembrane, score
KOOLEIAC_02006 1.62e-57 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
KOOLEIAC_02007 1.42e-113 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
KOOLEIAC_02008 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KOOLEIAC_02010 1.26e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KOOLEIAC_02011 3.28e-313 - - - T - - - GHKL domain
KOOLEIAC_02012 2.58e-182 - - - K - - - LytTr DNA-binding domain
KOOLEIAC_02013 1.91e-280 - - - M - - - Glycosyltransferase like family 2
KOOLEIAC_02014 9.58e-95 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KOOLEIAC_02015 2.09e-60 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KOOLEIAC_02016 1.27e-306 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
KOOLEIAC_02017 7.15e-176 - - - K ko:K03710 - ko00000,ko03000 UTRA domain
KOOLEIAC_02018 7.62e-270 ugpC - - E ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KOOLEIAC_02019 4.11e-68 - - - S - - - LPXTG-motif cell wall anchor domain protein
KOOLEIAC_02020 2.72e-182 - - - L - - - Winged helix-turn helix
KOOLEIAC_02021 1.35e-231 - - - - - - - -
KOOLEIAC_02022 6.14e-191 - - - U ko:K10439,ko:K10440 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
KOOLEIAC_02023 4.51e-222 rbsA 3.6.3.17 - G ko:K10441,ko:K10542,ko:K17215 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
KOOLEIAC_02024 6.91e-187 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
KOOLEIAC_02025 7.94e-167 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KOOLEIAC_02026 7.31e-22 tnp3521a2 - - L - - - Integrase core domain
KOOLEIAC_02027 7.78e-200 - - - - - - - -
KOOLEIAC_02028 0.0 - - - KLT - - - Domain of unknown function (DUF4032)
KOOLEIAC_02029 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KOOLEIAC_02030 8.55e-213 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
KOOLEIAC_02031 1.86e-221 rlmB 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KOOLEIAC_02032 5.36e-271 - - - EGP - - - Transmembrane secretion effector
KOOLEIAC_02033 0.0 nagE 2.7.1.193 - G ko:K02802,ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
KOOLEIAC_02034 1.58e-112 - 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KOOLEIAC_02035 1.55e-20 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KOOLEIAC_02036 0.0 pacL2 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
KOOLEIAC_02037 4.54e-124 - - - - - - - -
KOOLEIAC_02038 6.04e-144 dcd 3.5.4.13 - F ko:K01494 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dCTP deaminase family
KOOLEIAC_02039 9.4e-198 - - - - - - - -
KOOLEIAC_02040 7.21e-188 - - - S ko:K06999 - ko00000 Phospholipase/Carboxylesterase
KOOLEIAC_02041 6.17e-160 - - - S ko:K07090 - ko00000 membrane transporter protein
KOOLEIAC_02042 0.0 nhaP - - P ko:K03316 - ko00000 Sodium/hydrogen exchanger family
KOOLEIAC_02043 2.51e-102 tadA 3.5.4.1, 3.5.4.33 - FJ ko:K01485,ko:K11991 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KOOLEIAC_02044 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
KOOLEIAC_02045 9.36e-296 - - - GK - - - ROK family
KOOLEIAC_02046 1.62e-312 - - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_02047 1.63e-209 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_02048 2.91e-196 - - - G ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_02049 2e-240 - - - K - - - Periplasmic binding protein-like domain
KOOLEIAC_02050 1.36e-244 - - - K - - - helix_turn _helix lactose operon repressor
KOOLEIAC_02051 7.93e-306 - - - G ko:K02027,ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_02052 1.26e-296 - - - G - - - Protein of unknown function (DUF2961)
KOOLEIAC_02053 1.32e-315 - - - G ko:K02027,ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KOOLEIAC_02054 3.16e-239 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_02055 1.96e-187 - - - G ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KOOLEIAC_02056 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
KOOLEIAC_02057 0.0 - - - G - - - Raffinose synthase or seed imbibition protein Sip1
KOOLEIAC_02058 0.0 - 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
KOOLEIAC_02059 6.86e-294 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
KOOLEIAC_02060 1.19e-181 cobB2 - - K ko:K12410 - ko00000,ko01000 Sir2 family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)