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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MKDNEODP_00001	2.72e-187	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
MKDNEODP_00002	1.76e-296	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
MKDNEODP_00003	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MKDNEODP_00004	4.38e-10	-	-	-	L	-	-	-	Transposase
MKDNEODP_00005	7.15e-197	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00006	2.7e-208	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00007	2.68e-311	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_00008	3.08e-285	-	-	-	GK	-	-	-	ROK family
MKDNEODP_00009	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
MKDNEODP_00010	3.4e-106	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MKDNEODP_00011	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
MKDNEODP_00012	2.07e-187	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
MKDNEODP_00013	1.34e-178	-	-	-	-	-	-	-	-
MKDNEODP_00014	2.85e-50	-	-	-	S	-	-	-	Membrane
MKDNEODP_00015	1.81e-153	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MKDNEODP_00016	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
MKDNEODP_00017	6.09e-110	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00018	3.44e-138	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00019	3.87e-162	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_00020	3.76e-233	-	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MKDNEODP_00021	6.76e-114	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
MKDNEODP_00022	1.31e-93	scrK	-	-	G	-	-	-	pfkB family carbohydrate kinase
MKDNEODP_00023	4.97e-143	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
MKDNEODP_00024	4.31e-184	-	-	-	-	-	-	-	-
MKDNEODP_00025	2.58e-220	-	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKDNEODP_00026	8.83e-210	-	-	-	G	-	-	-	Glycosyl hydrolase, family 20, catalytic domain
MKDNEODP_00027	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
MKDNEODP_00028	4.12e-21	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MKDNEODP_00029	2.15e-110	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MKDNEODP_00030	0.0	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
MKDNEODP_00031	3.02e-281	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
MKDNEODP_00032	4.27e-121	-	-	-	-	-	-	-	-
MKDNEODP_00033	7.59e-61	-	-	-	L	-	-	-	Transposase
MKDNEODP_00034	4.62e-14	-	-	-	L	-	-	-	Transposase DDE domain
MKDNEODP_00035	9.88e-92	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport systems inner membrane component
MKDNEODP_00036	1.39e-95	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
MKDNEODP_00037	9.63e-73	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Extracellular solute-binding protein
MKDNEODP_00038	4.7e-60	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MKDNEODP_00039	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MKDNEODP_00040	1.27e-257	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MKDNEODP_00041	2.64e-220	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKDNEODP_00042	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
MKDNEODP_00043	1.47e-267	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKDNEODP_00044	3.15e-277	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MKDNEODP_00045	7.28e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKDNEODP_00047	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKDNEODP_00048	1.03e-106	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MKDNEODP_00049	1.62e-57	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
MKDNEODP_00050	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
MKDNEODP_00051	3.07e-172	-	-	-	O	-	-	-	Thioredoxin
MKDNEODP_00053	1.11e-281	rpfB	-	-	S	ko:K21688	-	ko00000	G5
MKDNEODP_00054	6e-215	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MKDNEODP_00055	2.19e-221	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MKDNEODP_00056	6.62e-140	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
MKDNEODP_00057	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
MKDNEODP_00058	3.62e-253	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
MKDNEODP_00059	0.0	-	-	-	-	-	-	-	-
MKDNEODP_00060	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
MKDNEODP_00061	3.71e-236	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MKDNEODP_00062	3.36e-292	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MKDNEODP_00063	1.49e-227	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
MKDNEODP_00064	2.41e-157	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MKDNEODP_00065	2.13e-118	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
MKDNEODP_00066	4.24e-224	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
MKDNEODP_00067	5.81e-45	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MKDNEODP_00068	3.25e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MKDNEODP_00069	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MKDNEODP_00070	6.2e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MKDNEODP_00071	1.36e-284	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MKDNEODP_00072	1.14e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
MKDNEODP_00073	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKDNEODP_00074	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKDNEODP_00075	1.08e-105	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
MKDNEODP_00076	0.0	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
MKDNEODP_00077	9.28e-317	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MKDNEODP_00078	2.28e-143	cpdA	2.1.2.2, 3.1.3.48, 3.1.4.17, 3.1.4.53	-	T	ko:K01104,ko:K01120,ko:K03651,ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,ko02025,map00230,map00670,map01100,map01110,map01130,map02025	ko00000,ko00001,ko00002,ko01000	protein tyrosine phosphatase activity
MKDNEODP_00079	2.66e-126	-	3.6.3.30	-	E	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MKDNEODP_00080	1.94e-245	-	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport systems inner membrane component
MKDNEODP_00081	3.12e-166	-	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_00082	1.24e-86	-	-	-	K	-	-	-	Transcriptional regulator, rpir family
MKDNEODP_00084	3.58e-38	-	-	-	L	-	-	-	RelB antitoxin
MKDNEODP_00085	1.35e-55	-	-	-	L	-	-	-	PFAM Integrase catalytic
MKDNEODP_00086	1.49e-48	-	-	-	-	-	-	-	-
MKDNEODP_00090	2.19e-74	-	-	-	F	-	-	-	Calcineurin-like phosphoesterase
MKDNEODP_00091	8.22e-105	ptxC	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00092	5.11e-101	-	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00093	1.7e-104	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MKDNEODP_00094	6.71e-144	-	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
MKDNEODP_00095	4.19e-24	-	-	-	K	-	-	-	Transcriptional regulator, rpir family
MKDNEODP_00096	5.22e-34	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MKDNEODP_00097	6.13e-257	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MKDNEODP_00098	1.24e-187	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
MKDNEODP_00099	5.44e-119	-	-	-	K	-	-	-	FCD
MKDNEODP_00100	5.1e-294	gnuT	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
MKDNEODP_00101	8.79e-112	gntK	2.7.1.12, 2.7.1.71	-	F	ko:K00851,ko:K00891	ko00030,ko00400,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00400,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate kinase
MKDNEODP_00102	4.39e-191	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase, C-terminal domain
MKDNEODP_00103	5.42e-110	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MKDNEODP_00104	3.36e-305	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
MKDNEODP_00105	5.24e-258	-	-	-	S	-	-	-	AAA ATPase domain
MKDNEODP_00106	5.94e-87	-	-	-	V	ko:K01990,ko:K21397	-	ko00000,ko00002,ko02000	Forkhead associated domain
MKDNEODP_00107	1.28e-155	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MKDNEODP_00108	9.71e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
MKDNEODP_00109	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
MKDNEODP_00110	2.65e-306	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
MKDNEODP_00111	2.54e-183	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MKDNEODP_00112	1.24e-231	-	-	-	L	-	-	-	Transposase
MKDNEODP_00113	8.83e-106	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MKDNEODP_00114	8.86e-107	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKDNEODP_00115	8.9e-123	-	-	-	C	ko:K06871	-	ko00000	radical SAM
MKDNEODP_00117	1.64e-171	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
MKDNEODP_00118	0.0	-	-	-	C	ko:K06871	-	ko00000	Iron-sulfur cluster-binding domain
MKDNEODP_00119	2.75e-245	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MKDNEODP_00120	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
MKDNEODP_00122	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_00123	7.54e-211	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00124	3.8e-226	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00125	1.62e-294	-	-	-	S	ko:K07133	-	ko00000	AAA domain
MKDNEODP_00126	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MKDNEODP_00127	1.34e-12	-	-	-	-	-	-	-	-
MKDNEODP_00128	2.76e-239	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	family 5
MKDNEODP_00129	1.64e-157	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
MKDNEODP_00130	1.73e-121	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
MKDNEODP_00131	2.49e-186	-	-	-	P	ko:K02031,ko:K02032,ko:K13892	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKDNEODP_00132	2.38e-83	-	-	-	M	-	-	-	Domain of unknown function (DUF1906)
MKDNEODP_00134	5.6e-45	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MKDNEODP_00135	4.51e-198	-	-	-	L	ko:K03546	-	ko00000,ko03400	ATPase involved in DNA repair
MKDNEODP_00137	1.92e-141	-	-	-	-	-	-	-	-
MKDNEODP_00140	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF1906)
MKDNEODP_00142	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MKDNEODP_00143	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MKDNEODP_00144	1.48e-14	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MKDNEODP_00145	1.65e-120	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_00146	0.0	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKDNEODP_00147	8.11e-72	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MKDNEODP_00148	9.06e-136	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
MKDNEODP_00149	4.29e-254	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MKDNEODP_00150	4.19e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
MKDNEODP_00151	5.37e-146	-	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKDNEODP_00152	2.63e-265	-	-	-	T	-	-	-	Histidine kinase
MKDNEODP_00153	5.79e-306	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_00154	4.68e-99	-	-	-	I	-	-	-	Sterol carrier protein
MKDNEODP_00155	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MKDNEODP_00156	2.06e-46	-	-	-	-	-	-	-	-
MKDNEODP_00157	9.63e-162	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
MKDNEODP_00158	3.01e-106	crgA	-	-	D	-	-	-	Involved in cell division
MKDNEODP_00159	1.64e-156	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
MKDNEODP_00160	1.5e-297	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MKDNEODP_00161	7.5e-153	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
MKDNEODP_00162	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MKDNEODP_00163	3.11e-221	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MKDNEODP_00164	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
MKDNEODP_00165	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MKDNEODP_00166	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
MKDNEODP_00167	1.73e-82	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
MKDNEODP_00168	6.12e-166	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
MKDNEODP_00169	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
MKDNEODP_00170	3.04e-262	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
MKDNEODP_00171	4.22e-188	-	-	-	EG	-	-	-	EamA-like transporter family
MKDNEODP_00172	1.47e-285	-	-	-	S	-	-	-	Putative esterase
MKDNEODP_00173	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
MKDNEODP_00174	6.74e-245	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKDNEODP_00175	5.55e-143	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
MKDNEODP_00176	1.53e-208	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MKDNEODP_00177	0.0	-	-	-	KL	-	-	-	Domain of unknown function (DUF3427)
MKDNEODP_00178	1.64e-98	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
MKDNEODP_00179	5.86e-68	-	-	-	S	-	-	-	Putative heavy-metal-binding
MKDNEODP_00180	8.94e-163	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
MKDNEODP_00181	4.14e-93	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
MKDNEODP_00182	4.84e-72	-	-	-	S	-	-	-	PfpI family
MKDNEODP_00185	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MKDNEODP_00186	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
MKDNEODP_00187	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
MKDNEODP_00188	2.77e-247	urtA	-	-	E	ko:K11959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
MKDNEODP_00189	7.88e-165	urtB	-	-	U	ko:K11960	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
MKDNEODP_00190	2.7e-203	urtC	-	-	U	ko:K01998,ko:K11961	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
MKDNEODP_00191	4.04e-147	urtD	-	-	S	ko:K11962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
MKDNEODP_00192	8.34e-128	urtE	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MKDNEODP_00193	2.66e-138	hoxN	-	-	U	ko:K07241	-	ko00000,ko02000	Belongs to the NiCoT transporter (TC 2.A.52) family
MKDNEODP_00194	6.14e-123	ureA	3.5.1.5	-	E	ko:K01430,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Urease, gamma subunit
MKDNEODP_00195	0.0	ureC	3.5.1.5	-	E	ko:K01427,ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Urease alpha-subunit, N-terminal domain
MKDNEODP_00196	9.64e-113	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MKDNEODP_00197	1.13e-101	ureF	-	-	J	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MKDNEODP_00198	3.67e-127	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MKDNEODP_00199	1.81e-116	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MKDNEODP_00200	6.26e-125	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MKDNEODP_00201	4.01e-260	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
MKDNEODP_00202	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
MKDNEODP_00203	5.53e-205	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MKDNEODP_00204	1.55e-125	-	3.2.1.4	GH5,GH9	S	ko:K01179,ko:K21449	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko02000	acid phosphatase activity
MKDNEODP_00206	7.78e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_00207	2.85e-152	mug	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
MKDNEODP_00208	7.23e-263	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
MKDNEODP_00209	9.71e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MKDNEODP_00210	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
MKDNEODP_00211	2.85e-200	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKDNEODP_00212	5.18e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKDNEODP_00213	3.42e-259	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MKDNEODP_00214	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
MKDNEODP_00215	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
MKDNEODP_00217	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
MKDNEODP_00218	8.38e-259	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MKDNEODP_00219	4.44e-65	bioN	-	-	P	ko:K16783	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MKDNEODP_00220	4.04e-91	bioM	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_00221	1.09e-74	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MKDNEODP_00222	5.06e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MKDNEODP_00223	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
MKDNEODP_00224	4.02e-238	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MKDNEODP_00225	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
MKDNEODP_00226	0.0	strK	3.1.3.1, 3.1.3.39	-	P	ko:K01077,ko:K04342	ko00521,ko00730,ko00790,ko01100,ko01130,ko02020,map00521,map00730,map00790,map01100,map01130,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
MKDNEODP_00227	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MKDNEODP_00228	2.8e-95	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MKDNEODP_00229	3.79e-231	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
MKDNEODP_00230	5.09e-128	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
MKDNEODP_00231	2.88e-270	-	-	-	F	-	-	-	Psort location CytoplasmicMembrane, score 10.00
MKDNEODP_00232	6.13e-263	-	-	-	H	-	-	-	long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
MKDNEODP_00233	3.35e-291	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
MKDNEODP_00234	9.22e-181	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
MKDNEODP_00235	5.91e-159	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
MKDNEODP_00236	2.59e-171	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
MKDNEODP_00237	7.3e-120	-	-	-	D	-	-	-	bacterial-type flagellum organization
MKDNEODP_00238	1.12e-245	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
MKDNEODP_00239	1.72e-135	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
MKDNEODP_00240	1.63e-131	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
MKDNEODP_00241	3.54e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
MKDNEODP_00242	4.43e-70	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
MKDNEODP_00243	4.26e-272	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
MKDNEODP_00244	9.91e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKDNEODP_00245	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
MKDNEODP_00246	1.93e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MKDNEODP_00247	8.03e-257	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MKDNEODP_00248	1.06e-64	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score
MKDNEODP_00249	3.35e-169	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
MKDNEODP_00250	1.17e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
MKDNEODP_00251	2.54e-267	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MKDNEODP_00252	1.25e-147	-	-	-	-	-	-	-	-
MKDNEODP_00253	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MKDNEODP_00254	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MKDNEODP_00255	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
MKDNEODP_00256	1.81e-212	-	-	-	I	-	-	-	PAP2 superfamily
MKDNEODP_00257	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKDNEODP_00258	3.65e-158	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MKDNEODP_00259	2.31e-259	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MKDNEODP_00260	1.6e-131	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MKDNEODP_00261	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
MKDNEODP_00262	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MKDNEODP_00263	1.46e-135	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
MKDNEODP_00264	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
MKDNEODP_00265	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
MKDNEODP_00266	5.49e-82	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
MKDNEODP_00267	1.83e-124	-	-	-	S	-	-	-	GtrA-like protein
MKDNEODP_00268	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_00269	6.16e-159	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MKDNEODP_00270	9.75e-202	-	-	-	-	-	-	-	-
MKDNEODP_00271	8.26e-218	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
MKDNEODP_00272	3.96e-197	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
MKDNEODP_00273	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MKDNEODP_00275	8e-33	-	-	-	S	ko:K07133	-	ko00000	AAA domain
MKDNEODP_00276	7.61e-228	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MKDNEODP_00279	8.81e-103	-	-	-	-	-	-	-	-
MKDNEODP_00280	5.06e-178	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
MKDNEODP_00281	4.49e-238	-	-	-	L	ko:K07485	-	ko00000	Transposase
MKDNEODP_00282	1.31e-288	-	2.1.1.113	-	L	ko:K00590	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
MKDNEODP_00283	1e-82	-	-	-	-	-	-	-	-
MKDNEODP_00285	2.21e-218	-	-	-	-	-	-	-	-
MKDNEODP_00287	0.0	-	-	-	-	-	-	-	-
MKDNEODP_00288	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
MKDNEODP_00289	1.43e-154	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
MKDNEODP_00290	1.28e-294	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
MKDNEODP_00291	1.66e-287	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MKDNEODP_00292	3.66e-275	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MKDNEODP_00293	4.85e-188	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKDNEODP_00294	9.42e-111	-	-	-	S	-	-	-	FMN_bind
MKDNEODP_00295	2e-136	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
MKDNEODP_00296	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
MKDNEODP_00297	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
MKDNEODP_00298	1.76e-295	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MKDNEODP_00299	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MKDNEODP_00300	2.51e-177	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
MKDNEODP_00301	1.24e-235	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
MKDNEODP_00302	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MKDNEODP_00304	1.64e-12	-	-	-	-	-	-	-	-
MKDNEODP_00306	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
MKDNEODP_00307	9.5e-239	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
MKDNEODP_00308	5.43e-157	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKDNEODP_00309	8.23e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
MKDNEODP_00310	3.96e-23	-	-	-	-	-	-	-	-
MKDNEODP_00311	1.78e-238	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MKDNEODP_00312	4.57e-304	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
MKDNEODP_00313	7.34e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
MKDNEODP_00314	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
MKDNEODP_00315	0.0	dinF	-	-	V	-	-	-	MatE
MKDNEODP_00316	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MKDNEODP_00317	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
MKDNEODP_00318	5.69e-184	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
MKDNEODP_00319	2.4e-51	-	-	-	S	-	-	-	granule-associated protein
MKDNEODP_00320	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
MKDNEODP_00321	6.88e-171	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MKDNEODP_00322	6.23e-243	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKDNEODP_00323	2.77e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MKDNEODP_00324	4.24e-97	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MKDNEODP_00325	2.15e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MKDNEODP_00326	1.92e-91	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MKDNEODP_00328	1.22e-150	-	-	-	-	-	-	-	-
MKDNEODP_00329	2.31e-166	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MKDNEODP_00330	3.12e-175	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MKDNEODP_00331	8.13e-93	-	-	-	V	ko:K01990,ko:K01992	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_00332	1.53e-138	-	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKDNEODP_00333	1.65e-266	-	-	-	T	-	-	-	Histidine kinase
MKDNEODP_00334	4.15e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_00336	5.18e-218	-	-	-	S	-	-	-	Protein conserved in bacteria
MKDNEODP_00337	0.0	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MKDNEODP_00338	1.23e-228	oppB1	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00339	7.07e-226	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
MKDNEODP_00340	0.0	oppD	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKDNEODP_00341	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MKDNEODP_00343	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_00344	0.0	-	-	-	S	ko:K07133	-	ko00000	AAA domain
MKDNEODP_00345	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
MKDNEODP_00346	5.34e-245	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MKDNEODP_00347	4.55e-305	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_00348	9.38e-229	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00349	2.58e-196	-	-	-	U	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00350	6.08e-247	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
MKDNEODP_00351	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MKDNEODP_00352	0.0	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
MKDNEODP_00353	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MKDNEODP_00354	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MKDNEODP_00355	2.28e-250	-	-	-	S	-	-	-	Fic/DOC family
MKDNEODP_00356	2.72e-237	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
MKDNEODP_00357	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MKDNEODP_00358	1.2e-203	-	-	-	S	-	-	-	Glutamine amidotransferase domain
MKDNEODP_00359	1.57e-173	-	-	-	T	ko:K06950	-	ko00000	HD domain
MKDNEODP_00361	8.74e-243	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MKDNEODP_00362	1.17e-300	-	-	-	V	-	-	-	ABC transporter permease
MKDNEODP_00363	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF4012)
MKDNEODP_00364	4.18e-245	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
MKDNEODP_00365	3.27e-256	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MKDNEODP_00366	0.0	glfT	2.4.1.288	GT2	S	ko:K16650	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MKDNEODP_00367	2.37e-213	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKDNEODP_00368	1.48e-131	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
MKDNEODP_00369	9.53e-166	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
MKDNEODP_00370	6.94e-229	-	-	-	M	-	-	-	Glycosyl transferases group 1
MKDNEODP_00371	5.8e-70	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
MKDNEODP_00372	2.38e-215	-	-	-	M	-	-	-	Glycosyl transferase family 2
MKDNEODP_00373	9.1e-234	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MKDNEODP_00374	3.47e-197	-	-	-	I	-	-	-	Acyltransferase family
MKDNEODP_00375	1.43e-06	-	-	-	M	-	-	-	Glycosyl transferase family 2
MKDNEODP_00376	4.13e-220	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_00377	1.67e-154	-	-	-	G	ko:K02025,ko:K17330	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00378	9.45e-161	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00379	1.15e-231	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MKDNEODP_00380	2.26e-283	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
MKDNEODP_00381	9.89e-201	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
MKDNEODP_00382	5.77e-94	-	2.3.1.57	-	K	ko:K03826,ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MKDNEODP_00383	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MKDNEODP_00384	2.77e-198	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MKDNEODP_00385	3.69e-200	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
MKDNEODP_00386	2.38e-167	-	-	-	P	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00387	1.02e-162	-	-	-	G	ko:K02026,ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00388	4.61e-262	-	-	-	G	ko:K02027,ko:K17329	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_00389	1.47e-129	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
MKDNEODP_00390	1.31e-92	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MKDNEODP_00391	2.23e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MKDNEODP_00392	2.48e-272	-	-	-	I	-	-	-	PAP2 superfamily
MKDNEODP_00393	3.19e-53	-	-	-	L	ko:K07450	-	ko00000	Resolvase, N terminal domain
MKDNEODP_00394	1.8e-168	-	-	-	L	ko:K07496	-	ko00000	Helix-turn-helix domain
MKDNEODP_00395	9.87e-122	-	-	-	S	-	-	-	Protein of unknown function (DUF1706)
MKDNEODP_00396	1.73e-161	-	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKDNEODP_00397	8.36e-130	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	PFAM Binding-protein-dependent transport system inner membrane component
MKDNEODP_00398	8.5e-128	-	-	-	P	ko:K02026,ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00399	1.43e-144	-	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
MKDNEODP_00400	1.21e-174	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Extracellular solute-binding protein
MKDNEODP_00401	8.77e-38	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
MKDNEODP_00402	2.27e-153	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
MKDNEODP_00403	7.69e-60	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
MKDNEODP_00404	1.04e-279	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_00405	6.43e-284	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_00406	7.8e-314	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_00407	5.84e-172	nanA	4.1.3.3, 4.3.3.7	-	EM	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
MKDNEODP_00408	4.24e-149	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
MKDNEODP_00410	2.97e-123	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MKDNEODP_00411	5.38e-309	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
MKDNEODP_00412	1.05e-181	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
MKDNEODP_00413	2.56e-195	-	4.1.2.28	-	EM	ko:K22397	ko00040,map00040	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
MKDNEODP_00414	1.8e-90	fucU	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
MKDNEODP_00415	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
MKDNEODP_00416	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
MKDNEODP_00417	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MKDNEODP_00418	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
MKDNEODP_00419	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
MKDNEODP_00420	2.33e-174	-	-	-	-	-	-	-	-
MKDNEODP_00421	1.53e-288	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
MKDNEODP_00422	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MKDNEODP_00423	5.29e-307	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MKDNEODP_00424	5.17e-179	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
MKDNEODP_00425	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MKDNEODP_00426	2.22e-169	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MKDNEODP_00427	1.4e-264	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
MKDNEODP_00428	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
MKDNEODP_00429	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKDNEODP_00430	4.96e-310	-	4.4.1.8	-	E	ko:K00842,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
MKDNEODP_00431	2.18e-218	-	-	-	K	-	-	-	LysR substrate binding domain protein
MKDNEODP_00432	3.57e-179	-	-	-	G	-	-	-	Transmembrane secretion effector
MKDNEODP_00433	2.83e-154	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKDNEODP_00434	1.73e-238	bglA	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
MKDNEODP_00435	0.0	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	beta-mannosidase
MKDNEODP_00436	2.58e-155	-	-	-	P	ko:K02026,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00437	9.88e-171	-	-	-	P	ko:K10189,ko:K10241	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00438	1.4e-205	-	-	-	G	ko:K10240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_00439	2.46e-138	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MKDNEODP_00440	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MKDNEODP_00441	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MKDNEODP_00442	1.9e-295	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
MKDNEODP_00443	3.57e-261	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MKDNEODP_00444	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
MKDNEODP_00445	3.14e-11	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MKDNEODP_00446	2.92e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF1778)
MKDNEODP_00448	2.74e-166	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_00449	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
MKDNEODP_00450	2.48e-231	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
MKDNEODP_00451	6.85e-313	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
MKDNEODP_00452	2.47e-180	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
MKDNEODP_00453	1.47e-262	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
MKDNEODP_00454	1.91e-189	-	-	-	S	ko:K07046	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Amidohydrolase
MKDNEODP_00455	9.59e-101	fucU	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
MKDNEODP_00456	7.19e-210	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
MKDNEODP_00457	6.43e-288	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
MKDNEODP_00458	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
MKDNEODP_00459	4.13e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MKDNEODP_00460	3.99e-53	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
MKDNEODP_00461	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MKDNEODP_00462	1.65e-253	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MKDNEODP_00463	7.95e-292	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
MKDNEODP_00465	2.45e-44	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MKDNEODP_00466	3.23e-193	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MKDNEODP_00467	8.3e-95	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MKDNEODP_00468	3.53e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MKDNEODP_00470	1.32e-168	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MKDNEODP_00471	1.5e-102	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
MKDNEODP_00472	1.18e-27	-	-	-	S	-	-	-	Aldo/keto reductase family
MKDNEODP_00473	2.77e-15	-	-	-	S	-	-	-	Aldo/keto reductase family
MKDNEODP_00474	3.08e-214	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MKDNEODP_00475	6.45e-215	CP_1020	-	-	S	-	-	-	zinc ion binding
MKDNEODP_00476	1.31e-163	-	-	-	S	-	-	-	Plasmid pRiA4b ORF-3-like protein
MKDNEODP_00477	1.4e-43	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	EamA-like transporter family
MKDNEODP_00480	1.75e-21	-	-	-	E	-	-	-	Rard protein
MKDNEODP_00481	1.17e-253	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MKDNEODP_00482	9.97e-42	-	-	-	S	-	-	-	MazG-like family
MKDNEODP_00483	1.43e-09	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKDNEODP_00484	3.63e-76	CP_1020	-	-	S	-	-	-	zinc ion binding
MKDNEODP_00485	9.56e-179	-	-	-	-	-	-	-	-
MKDNEODP_00486	7.59e-122	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
MKDNEODP_00488	2.96e-206	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MKDNEODP_00489	3.44e-201	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_00490	6.25e-308	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
MKDNEODP_00491	1.98e-105	-	-	-	-	-	-	-	-
MKDNEODP_00492	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
MKDNEODP_00493	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
MKDNEODP_00494	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MKDNEODP_00495	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
MKDNEODP_00496	7.3e-227	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MKDNEODP_00499	2.78e-176	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MKDNEODP_00500	1.17e-226	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
MKDNEODP_00501	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MKDNEODP_00502	6.75e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MKDNEODP_00503	1.98e-162	-	-	-	S	-	-	-	UPF0126 domain
MKDNEODP_00504	2.55e-148	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	Psort location Cytoplasmic, score 8.87
MKDNEODP_00505	1.38e-130	-	-	-	L	-	-	-	Phage integrase family
MKDNEODP_00506	9.2e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
MKDNEODP_00507	4.56e-21	-	-	-	-	-	-	-	-
MKDNEODP_00519	3.13e-15	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
MKDNEODP_00521	0.000157	wag31	-	-	D	-	-	-	Cell division initiation protein
MKDNEODP_00522	2.52e-85	-	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
MKDNEODP_00524	4.21e-07	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MKDNEODP_00525	6.26e-42	-	-	-	V	-	-	-	HNH endonuclease
MKDNEODP_00531	1.02e-65	-	-	-	L	-	-	-	tRNA (guanine-N2-)-methyltransferase activity
MKDNEODP_00540	3.61e-10	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
MKDNEODP_00551	1.81e-50	-	-	-	-	-	-	-	-
MKDNEODP_00552	1.45e-32	-	-	-	-	-	-	-	-
MKDNEODP_00554	1.33e-90	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
MKDNEODP_00557	8.42e-44	-	-	-	-	-	-	-	-
MKDNEODP_00562	1.25e-53	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MKDNEODP_00567	4.84e-65	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
MKDNEODP_00568	5.17e-46	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MKDNEODP_00577	1.26e-18	-	-	-	K	-	-	-	Helix-turn-helix domain
MKDNEODP_00579	1.19e-14	-	-	-	-	-	-	-	-
MKDNEODP_00581	7.79e-16	intA	-	-	L	-	-	-	Phage integrase family
MKDNEODP_00583	1.51e-26	-	-	-	-	-	-	-	-
MKDNEODP_00584	3.87e-95	intA	-	-	L	-	-	-	Phage integrase family
MKDNEODP_00585	1.44e-197	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MKDNEODP_00588	2.32e-212	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 7.50
MKDNEODP_00589	8.96e-149	-	-	-	S	-	-	-	AAA ATPase domain
MKDNEODP_00590	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
MKDNEODP_00591	1.29e-266	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MKDNEODP_00592	2.13e-173	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
MKDNEODP_00593	5.08e-153	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
MKDNEODP_00594	0.0	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKDNEODP_00595	4.02e-140	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKDNEODP_00596	2.59e-213	tcsS2	-	-	T	-	-	-	Histidine kinase
MKDNEODP_00597	3.65e-119	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MKDNEODP_00598	1.27e-112	tnp7109-2	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
MKDNEODP_00599	4.88e-62	tnp7109-2	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
MKDNEODP_00601	4.39e-19	-	-	-	L	-	-	-	Transposase
MKDNEODP_00602	4.69e-218	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MKDNEODP_00604	1.71e-31	-	-	-	L	-	-	-	Transposase
MKDNEODP_00606	2.53e-129	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MKDNEODP_00607	1.43e-301	-	-	-	-	-	-	-	-
MKDNEODP_00608	1.95e-26	-	-	-	S	-	-	-	Bacteriocin (Lactococcin_972)
MKDNEODP_00609	2.34e-34	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MKDNEODP_00610	5.88e-126	-	-	-	T	-	-	-	Histidine kinase
MKDNEODP_00611	3.57e-311	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
MKDNEODP_00612	1.21e-142	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
MKDNEODP_00613	4.6e-135	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
MKDNEODP_00614	3.39e-31	araE	-	-	EGP	ko:K02100	-	ko00000,ko02000	Major facilitator Superfamily
MKDNEODP_00615	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
MKDNEODP_00617	1.87e-164	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
MKDNEODP_00619	3.57e-267	-	-	-	L	ko:K07485	-	ko00000	Transposase
MKDNEODP_00620	7.02e-114	-	-	-	-	-	-	-	-
MKDNEODP_00621	2.94e-224	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MKDNEODP_00622	1.01e-164	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_00623	2.62e-152	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKDNEODP_00624	6.49e-57	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_00625	1.69e-30	-	-	-	K	-	-	-	trisaccharide binding
MKDNEODP_00626	1.34e-137	-	-	-	K	-	-	-	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKDNEODP_00627	4.66e-147	-	-	-	T	-	-	-	Histidine kinase
MKDNEODP_00628	6.69e-142	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MKDNEODP_00629	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MKDNEODP_00630	4.11e-34	-	-	-	K	ko:K03088	-	ko00000,ko03021	Psort location Cytoplasmic, score
MKDNEODP_00632	6.17e-261	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MKDNEODP_00633	8.15e-183	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MKDNEODP_00634	3.66e-58	-	-	-	-	-	-	-	-
MKDNEODP_00635	1.74e-246	-	-	-	-	-	-	-	-
MKDNEODP_00636	1.87e-254	-	-	-	M	-	-	-	CHAP domain
MKDNEODP_00637	0.0	-	-	-	U	-	-	-	type IV secretory pathway VirB4
MKDNEODP_00638	9.69e-45	-	-	-	S	-	-	-	PrgI family protein
MKDNEODP_00639	1.98e-181	-	-	-	L	-	-	-	IstB-like ATP binding protein
MKDNEODP_00640	1.99e-303	-	-	-	L	-	-	-	PFAM Integrase catalytic
MKDNEODP_00641	1.67e-187	-	-	-	-	-	-	-	-
MKDNEODP_00642	7.45e-51	-	-	-	-	-	-	-	-
MKDNEODP_00644	0.0	-	-	-	D	-	-	-	Cell surface antigen C-terminus
MKDNEODP_00645	2.32e-152	-	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
MKDNEODP_00646	2.17e-122	-	-	-	K	-	-	-	FR47-like protein
MKDNEODP_00647	0.0	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
MKDNEODP_00648	7.39e-54	-	-	-	-	-	-	-	-
MKDNEODP_00649	3.57e-130	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
MKDNEODP_00650	5.14e-112	-	-	-	S	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
MKDNEODP_00651	2.35e-40	-	-	-	S	-	-	-	Helix-turn-helix domain
MKDNEODP_00653	5.32e-11	-	-	-	-	-	-	-	-
MKDNEODP_00654	4.1e-84	-	-	-	K	-	-	-	Protein of unknown function, DUF488
MKDNEODP_00655	3.4e-98	-	-	-	-	-	-	-	-
MKDNEODP_00656	1.69e-200	-	-	-	-	-	-	-	-
MKDNEODP_00657	6.36e-21	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
MKDNEODP_00659	1.45e-72	-	-	-	S	-	-	-	Virulence protein RhuM family
MKDNEODP_00660	3.89e-05	-	-	-	S	-	-	-	Virulence protein RhuM family
MKDNEODP_00662	1.92e-58	-	-	-	K	-	-	-	Protein of unknown function, DUF488
MKDNEODP_00663	8.97e-73	-	-	-	KL	-	-	-	DEAD-like helicases superfamily
MKDNEODP_00664	1.44e-140	-	-	-	KL	-	-	-	DEAD-like helicases superfamily
MKDNEODP_00665	3.24e-293	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
MKDNEODP_00666	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MKDNEODP_00667	3.74e-155	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MKDNEODP_00668	1.3e-87	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MKDNEODP_00669	2.56e-220	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
MKDNEODP_00670	1.51e-259	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MKDNEODP_00671	1.08e-39	-	-	-	-	-	-	-	-
MKDNEODP_00672	1.33e-159	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MKDNEODP_00673	3.42e-233	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MKDNEODP_00674	2.74e-203	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
MKDNEODP_00675	1.74e-223	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
MKDNEODP_00676	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MKDNEODP_00677	3.7e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
MKDNEODP_00678	4.82e-227	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MKDNEODP_00679	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
MKDNEODP_00680	9.88e-239	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MKDNEODP_00681	6.39e-198	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
MKDNEODP_00682	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MKDNEODP_00683	3.11e-124	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
MKDNEODP_00684	5.15e-247	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MKDNEODP_00685	1.08e-120	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
MKDNEODP_00686	2.56e-151	-	-	-	-	-	-	-	-
MKDNEODP_00687	4.96e-67	-	-	-	-	-	-	-	-
MKDNEODP_00688	9.61e-120	-	-	-	S	-	-	-	AIPR protein
MKDNEODP_00689	2.13e-128	-	-	-	M	-	-	-	domain protein
MKDNEODP_00690	0.0	-	-	-	M	-	-	-	Conserved repeat domain
MKDNEODP_00691	7.07e-103	-	-	-	-	-	-	-	-
MKDNEODP_00692	1.23e-09	-	-	-	-	-	-	-	-
MKDNEODP_00694	2.79e-32	dexB	2.4.1.7, 3.2.1.20, 3.2.1.51, 3.2.1.70, 3.2.1.93, 3.2.1.97	GH101,GH13,GH29,GH31	G	ko:K00690,ko:K01187,ko:K01206,ko:K01215,ko:K01226,ko:K17624	ko00052,ko00500,ko00511,ko01100,map00052,map00500,map00511,map01100	ko00000,ko00001,ko01000,ko04147	hydrolase activity, hydrolyzing O-glycosyl compounds
MKDNEODP_00695	2.89e-123	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MKDNEODP_00696	0.0	fas	-	-	I	ko:K11533	ko00061,ko01100,ko01212,ko04931,map00061,map01100,map01212,map04931	ko00000,ko00001,ko00002,ko01000,ko01004	Beta-ketoacyl synthase, C-terminal domain
MKDNEODP_00697	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
MKDNEODP_00698	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
MKDNEODP_00699	1.45e-17	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MKDNEODP_00700	2.63e-189	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
MKDNEODP_00701	0.0	-	-	-	-	-	-	-	-
MKDNEODP_00702	1.45e-179	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
MKDNEODP_00703	6.05e-170	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
MKDNEODP_00704	7.19e-196	-	-	-	K	-	-	-	Bacterial transcriptional regulator
MKDNEODP_00707	4.38e-205	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MKDNEODP_00708	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MKDNEODP_00709	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MKDNEODP_00710	2.11e-101	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKDNEODP_00711	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MKDNEODP_00712	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MKDNEODP_00713	1.44e-164	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MKDNEODP_00714	7.06e-132	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
MKDNEODP_00715	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
MKDNEODP_00716	0.0	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
MKDNEODP_00717	1.65e-93	-	-	-	L	-	-	-	Transposase
MKDNEODP_00718	4.7e-136	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MKDNEODP_00719	3.69e-195	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MKDNEODP_00720	9.46e-200	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00721	7.73e-233	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MKDNEODP_00722	3.71e-316	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_00723	3.42e-174	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
MKDNEODP_00724	5.29e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
MKDNEODP_00725	6.35e-181	nfrA	-	-	C	-	-	-	Nitroreductase family
MKDNEODP_00726	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
MKDNEODP_00727	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
MKDNEODP_00728	1.37e-58	-	-	-	-	-	-	-	-
MKDNEODP_00729	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKDNEODP_00730	7.53e-150	-	-	-	-	-	-	-	-
MKDNEODP_00731	1.8e-234	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MKDNEODP_00732	1.62e-143	-	-	-	Q	-	-	-	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKDNEODP_00733	1.71e-176	-	-	-	Q	-	-	-	Ketoacyl-synthetase C-terminal extension
MKDNEODP_00734	1.22e-18	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
MKDNEODP_00736	1.93e-17	-	-	-	-	-	-	-	-
MKDNEODP_00737	7.49e-243	-	-	-	L	-	-	-	PFAM Integrase catalytic
MKDNEODP_00738	6.85e-216	tnp7109-2	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
MKDNEODP_00739	8.49e-57	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
MKDNEODP_00740	1.71e-65	-	-	-	-	-	-	-	-
MKDNEODP_00742	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
MKDNEODP_00744	8.36e-107	-	-	-	M	-	-	-	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MKDNEODP_00746	2.81e-60	-	-	-	P	-	-	-	Major facilitator superfamily
MKDNEODP_00747	1.76e-12	-	-	-	V	-	-	-	Abi-like protein
MKDNEODP_00748	1.54e-83	-	-	-	V	-	-	-	Abi-like protein
MKDNEODP_00749	9.26e-45	-	-	-	-	-	-	-	-
MKDNEODP_00751	9.2e-22	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MKDNEODP_00753	5.42e-238	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Divergent AAA domain protein
MKDNEODP_00757	1.88e-42	-	-	-	-	-	-	-	-
MKDNEODP_00759	8.11e-202	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MKDNEODP_00760	5.63e-255	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MKDNEODP_00763	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
MKDNEODP_00764	3.91e-267	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
MKDNEODP_00765	3.82e-227	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MKDNEODP_00766	0.0	-	-	-	S	-	-	-	AI-2E family transporter
MKDNEODP_00767	1.33e-293	-	-	-	M	-	-	-	Glycosyl transferase family 21
MKDNEODP_00768	2.36e-206	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_00769	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
MKDNEODP_00770	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
MKDNEODP_00771	1.58e-264	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MKDNEODP_00772	2.03e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MKDNEODP_00773	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MKDNEODP_00775	2.43e-137	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
MKDNEODP_00776	1.45e-202	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MKDNEODP_00777	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MKDNEODP_00778	3.16e-119	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
MKDNEODP_00779	2.56e-217	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
MKDNEODP_00780	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
MKDNEODP_00781	7.47e-262	-	-	-	EGP	-	-	-	Major facilitator Superfamily
MKDNEODP_00783	2.41e-46	-	-	-	L	-	-	-	Transposase, Mutator family
MKDNEODP_00784	3.4e-120	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_00785	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MKDNEODP_00786	8.16e-78	-	-	-	K	-	-	-	Virulence activator alpha C-term
MKDNEODP_00788	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_00790	1.96e-224	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MKDNEODP_00791	1.4e-88	-	-	-	EGP	-	-	-	Major facilitator superfamily
MKDNEODP_00792	2.54e-208	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
MKDNEODP_00793	2.32e-90	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MKDNEODP_00794	2.49e-186	-	-	-	-	-	-	-	-
MKDNEODP_00795	3.98e-23	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
MKDNEODP_00796	4.31e-32	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_00797	1.87e-86	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MKDNEODP_00798	6.05e-291	xylR	-	-	GK	-	-	-	ROK family
MKDNEODP_00800	6.44e-49	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
MKDNEODP_00801	1.17e-246	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MKDNEODP_00802	4.32e-201	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MKDNEODP_00803	1.65e-265	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
MKDNEODP_00804	1.71e-170	-	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MKDNEODP_00805	1.17e-217	-	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MKDNEODP_00806	3.67e-194	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
MKDNEODP_00807	1.08e-155	livF	-	-	E	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_00808	1.26e-51	maa	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	O-acyltransferase activity
MKDNEODP_00809	1.68e-154	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
MKDNEODP_00810	2.46e-274	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
MKDNEODP_00811	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MKDNEODP_00812	3.99e-149	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MKDNEODP_00813	0.0	-	-	-	L	-	-	-	PIF1-like helicase
MKDNEODP_00814	3.44e-77	-	-	-	S	ko:K06990	-	ko00000,ko04812	AMMECR1
MKDNEODP_00815	5.14e-43	-	-	-	S	ko:K06990	-	ko00000,ko04812	AMMECR1
MKDNEODP_00816	9.23e-30	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
MKDNEODP_00817	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MKDNEODP_00818	1.7e-70	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
MKDNEODP_00819	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
MKDNEODP_00820	3.5e-184	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MKDNEODP_00821	1.07e-193	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MKDNEODP_00822	3.68e-314	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
MKDNEODP_00823	1.65e-223	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
MKDNEODP_00824	1.72e-268	-	-	-	K	-	-	-	WYL domain
MKDNEODP_00825	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
MKDNEODP_00826	2.65e-103	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0150
MKDNEODP_00827	4.04e-46	-	-	-	-	-	-	-	-
MKDNEODP_00828	2.01e-47	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MKDNEODP_00829	2.73e-109	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MKDNEODP_00830	1.61e-252	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MKDNEODP_00831	1.14e-294	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class-V
MKDNEODP_00832	1.36e-10	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
MKDNEODP_00833	4.21e-15	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
MKDNEODP_00834	1.25e-245	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
MKDNEODP_00836	8.33e-99	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
MKDNEODP_00837	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
MKDNEODP_00838	1.4e-117	ywrO	-	-	S	-	-	-	Flavodoxin-like fold
MKDNEODP_00839	8.95e-297	-	-	-	S	-	-	-	peptidyl-serine autophosphorylation
MKDNEODP_00840	6.67e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKDNEODP_00841	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKDNEODP_00842	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
MKDNEODP_00843	1.25e-183	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MKDNEODP_00844	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
MKDNEODP_00845	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
MKDNEODP_00846	2.14e-76	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
MKDNEODP_00847	2.9e-61	-	-	-	S	-	-	-	Nucleotidyltransferase domain
MKDNEODP_00848	2.55e-91	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
MKDNEODP_00849	1.5e-296	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
MKDNEODP_00850	8.03e-110	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKDNEODP_00851	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
MKDNEODP_00852	0.0	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
MKDNEODP_00853	1.11e-208	-	-	-	-	-	-	-	-
MKDNEODP_00854	0.0	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
MKDNEODP_00855	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
MKDNEODP_00856	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
MKDNEODP_00857	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
MKDNEODP_00858	3.07e-200	-	-	-	P	-	-	-	VTC domain
MKDNEODP_00859	1.54e-144	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
MKDNEODP_00860	0.0	-	3.1.4.52	-	T	ko:K14051	ko02024,ko02026,map02024,map02026	ko00000,ko00001,ko01000	Putative diguanylate phosphodiesterase
MKDNEODP_00861	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MKDNEODP_00862	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
MKDNEODP_00863	3.06e-173	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MKDNEODP_00864	7.79e-211	rihB	3.2.2.1, 3.2.2.8	-	F	ko:K01239,ko:K01250,ko:K10213	ko00230,ko00240,ko00760,ko01100,map00230,map00240,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
MKDNEODP_00865	5.61e-240	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_00866	1.73e-16	iunH2	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
MKDNEODP_00867	7.25e-206	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKDNEODP_00868	3.08e-222	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
MKDNEODP_00869	9.68e-138	-	-	-	K	-	-	-	FCD
MKDNEODP_00870	4.06e-181	-	-	-	L	-	-	-	Domain of unknown function (DUF4862)
MKDNEODP_00871	4.56e-153	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MKDNEODP_00872	1.59e-147	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MKDNEODP_00873	0.0	neu	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
MKDNEODP_00874	0.0	oppA7	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MKDNEODP_00875	9.16e-215	oppB6	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00876	0.0	oppCD2	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
MKDNEODP_00877	5.48e-181	oppF	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_00878	8.6e-206	nanA	4.1.3.3, 4.3.3.7	-	EM	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
MKDNEODP_00879	9.15e-308	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
MKDNEODP_00880	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MKDNEODP_00881	1.28e-256	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_00882	4.24e-195	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00883	9.99e-198	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00884	4.28e-254	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MKDNEODP_00885	8.14e-201	-	-	-	I	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
MKDNEODP_00886	2.28e-58	-	-	-	L	-	-	-	Transposase, Mutator family
MKDNEODP_00887	7.83e-83	-	-	-	L	-	-	-	PFAM Integrase catalytic
MKDNEODP_00888	7.51e-16	-	-	-	L	-	-	-	Helix-turn-helix domain
MKDNEODP_00889	1.12e-182	uxuT	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
MKDNEODP_00890	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
MKDNEODP_00892	1.29e-57	-	-	-	G	ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
MKDNEODP_00893	6.63e-68	-	-	-	K	ko:K02529,ko:K05499	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MKDNEODP_00894	4.05e-89	-	-	-	K	ko:K02529,ko:K05499	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
MKDNEODP_00895	2.21e-286	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MKDNEODP_00896	1.82e-295	-	4.2.1.8	-	M	ko:K08323	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	mandelate racemase muconate lactonizing
MKDNEODP_00897	5.93e-242	mtlD	1.1.1.57, 1.1.1.58	-	G	ko:K00040,ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
MKDNEODP_00898	3.48e-218	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Glucuronate isomerase
MKDNEODP_00899	2.76e-68	-	-	-	FG	-	-	-	bis(5'-adenosyl)-triphosphatase activity
MKDNEODP_00900	7.6e-53	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
MKDNEODP_00901	2.33e-49	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
MKDNEODP_00902	5.58e-317	-	-	-	L	-	-	-	PFAM Integrase catalytic
MKDNEODP_00903	8.3e-78	-	-	-	-	-	-	-	-
MKDNEODP_00906	3.31e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
MKDNEODP_00907	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
MKDNEODP_00908	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
MKDNEODP_00909	0.0	-	-	-	S	-	-	-	PGAP1-like protein
MKDNEODP_00910	1.33e-69	-	-	-	-	-	-	-	-
MKDNEODP_00911	3.86e-90	-	-	-	-	-	-	-	-
MKDNEODP_00912	7.86e-224	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
MKDNEODP_00913	1.51e-237	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
MKDNEODP_00914	3.68e-117	-	-	-	-	-	-	-	-
MKDNEODP_00915	1.04e-219	-	-	-	S	-	-	-	Protein of unknown function DUF58
MKDNEODP_00916	6.79e-249	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
MKDNEODP_00917	1.02e-171	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MKDNEODP_00918	8.52e-95	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
MKDNEODP_00919	2.18e-51	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MKDNEODP_00920	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MKDNEODP_00921	2.78e-55	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
MKDNEODP_00922	5.32e-113	-	-	-	-	-	-	-	-
MKDNEODP_00923	2.26e-170	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
MKDNEODP_00924	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MKDNEODP_00925	1.01e-86	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MKDNEODP_00926	3.16e-247	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
MKDNEODP_00927	1.67e-223	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
MKDNEODP_00928	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
MKDNEODP_00929	0.0	codA	3.5.4.1, 3.5.4.21	-	F	ko:K01485,ko:K03365	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
MKDNEODP_00930	0.0	-	-	-	QT	-	-	-	Purine catabolism regulatory protein-like family
MKDNEODP_00931	0.0	proP	-	-	EGP	ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
MKDNEODP_00932	3.69e-181	-	3.5.2.10	-	S	ko:K01470	ko00330,map00330	ko00000,ko00001,ko01000	Creatinine amidohydrolase
MKDNEODP_00933	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
MKDNEODP_00934	0.0	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
MKDNEODP_00935	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
MKDNEODP_00936	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MKDNEODP_00937	3.55e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF559)
MKDNEODP_00938	7.84e-181	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
MKDNEODP_00939	1.98e-194	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MKDNEODP_00940	3.05e-137	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00941	3.82e-238	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00942	0.0	-	-	-	I	-	-	-	PAP2 superfamily
MKDNEODP_00943	4.97e-31	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
MKDNEODP_00944	7.07e-250	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
MKDNEODP_00945	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
MKDNEODP_00946	1.92e-314	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
MKDNEODP_00947	8.57e-316	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_00948	9.11e-236	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MKDNEODP_00949	6.5e-106	-	-	-	J	-	-	-	TM2 domain
MKDNEODP_00950	8.24e-71	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
MKDNEODP_00951	7.75e-62	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
MKDNEODP_00952	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MKDNEODP_00953	2.87e-138	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MKDNEODP_00954	5.22e-257	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
MKDNEODP_00955	1.56e-179	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MKDNEODP_00956	1.25e-284	-	-	-	E	-	-	-	Aminotransferase class I and II
MKDNEODP_00957	1.2e-178	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_00958	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MKDNEODP_00959	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
MKDNEODP_00960	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MKDNEODP_00961	7.45e-257	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MKDNEODP_00962	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
MKDNEODP_00963	4.66e-164	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MKDNEODP_00964	1.52e-145	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_00965	7.09e-136	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MKDNEODP_00966	1.72e-122	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MKDNEODP_00967	1.05e-303	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
MKDNEODP_00968	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MKDNEODP_00969	2.09e-214	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MKDNEODP_00970	4.38e-134	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MKDNEODP_00972	3.16e-169	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
MKDNEODP_00973	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
MKDNEODP_00974	3.56e-152	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
MKDNEODP_00975	2.04e-125	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00976	1.31e-142	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00977	2.19e-144	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
MKDNEODP_00978	1.1e-165	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MKDNEODP_00979	9.3e-291	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
MKDNEODP_00980	2.28e-57	-	-	-	O	-	-	-	Glutaredoxin
MKDNEODP_00981	2.84e-199	-	-	-	E	-	-	-	Glyoxalase-like domain
MKDNEODP_00982	4.46e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKDNEODP_00983	5.85e-253	-	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen decarboxylase (URO-D)
MKDNEODP_00984	1.45e-280	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
MKDNEODP_00985	0.0	-	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
MKDNEODP_00986	0.0	-	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_00987	3.12e-293	-	-	-	S	ko:K01436	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
MKDNEODP_00988	4.77e-306	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
MKDNEODP_00989	1.19e-177	ehuA	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_00990	4.62e-184	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Bacterial periplasmic substrate-binding proteins
MKDNEODP_00991	2.37e-143	tcyA/tcyB	-	-	E	ko:K02029,ko:K02424,ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Binding-protein-dependent transport system inner membrane component
MKDNEODP_00992	5.52e-171	hflK	-	-	O	-	-	-	prohibitin homologues
MKDNEODP_00993	4.89e-201	-	-	-	S	-	-	-	Patatin-like phospholipase
MKDNEODP_00994	1.34e-189	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MKDNEODP_00995	1.93e-210	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
MKDNEODP_00996	1.8e-164	-	-	-	S	-	-	-	Vitamin K epoxide reductase
MKDNEODP_00997	1.8e-215	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
MKDNEODP_00998	1.13e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
MKDNEODP_00999	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
MKDNEODP_01000	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MKDNEODP_01001	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
MKDNEODP_01002	4.86e-202	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MKDNEODP_01003	2.15e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
MKDNEODP_01005	0.0	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
MKDNEODP_01006	1.28e-274	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MKDNEODP_01007	1.14e-294	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MKDNEODP_01008	0.0	-	-	-	I	-	-	-	acetylesterase activity
MKDNEODP_01009	7.4e-145	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MKDNEODP_01010	4.53e-196	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MKDNEODP_01011	2.74e-265	-	-	-	F	-	-	-	nucleoside hydrolase
MKDNEODP_01012	1.63e-259	-	-	-	P	-	-	-	NMT1/THI5 like
MKDNEODP_01013	3.12e-177	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01014	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MKDNEODP_01015	6.47e-303	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
MKDNEODP_01016	2.17e-243	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MKDNEODP_01017	0.0	-	-	-	O	ko:K13963	ko05146,map05146	ko00000,ko00001	SERine Proteinase INhibitors
MKDNEODP_01018	2.35e-23	-	-	-	-	-	-	-	-
MKDNEODP_01019	3.71e-86	-	-	-	T	-	-	-	Histidine kinase
MKDNEODP_01020	2.73e-80	-	-	-	S	-	-	-	Thiamine-binding protein
MKDNEODP_01021	1.24e-186	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MKDNEODP_01022	5.8e-290	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
MKDNEODP_01023	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MKDNEODP_01024	3.06e-211	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MKDNEODP_01025	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
MKDNEODP_01026	1.08e-304	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKDNEODP_01027	1.5e-259	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MKDNEODP_01028	2.78e-103	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MKDNEODP_01029	3.18e-56	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MKDNEODP_01030	6.92e-142	-	-	-	V	-	-	-	DivIVA protein
MKDNEODP_01031	8.56e-116	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MKDNEODP_01032	2.49e-229	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MKDNEODP_01033	9.81e-68	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_01034	4e-127	-	-	-	-	-	-	-	-
MKDNEODP_01035	2.75e-166	-	-	-	S	ko:K07058	-	ko00000	Virulence factor BrkB
MKDNEODP_01036	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
MKDNEODP_01037	1.83e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF4186)
MKDNEODP_01038	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
MKDNEODP_01039	2.64e-17	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_01040	2.2e-192	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01041	1.39e-194	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01043	4.25e-09	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_01046	8.17e-22	-	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal
MKDNEODP_01047	3.47e-229	-	-	-	L	-	-	-	Transposase, Mutator family
MKDNEODP_01048	3.44e-302	-	-	-	L	-	-	-	Transposase
MKDNEODP_01049	3.73e-168	-	-	-	L	-	-	-	Transposase
MKDNEODP_01050	3.99e-161	-	-	-	L	-	-	-	Transposase
MKDNEODP_01051	4.72e-45	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01053	3.79e-09	-	-	-	L	-	-	-	Single-strand binding protein family
MKDNEODP_01054	2.03e-165	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MKDNEODP_01055	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
MKDNEODP_01056	5.5e-56	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
MKDNEODP_01057	1.29e-279	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
MKDNEODP_01058	4.22e-127	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MKDNEODP_01059	8.81e-204	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
MKDNEODP_01060	4.69e-235	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MKDNEODP_01061	1.47e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKDNEODP_01062	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MKDNEODP_01063	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKDNEODP_01064	6.82e-251	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MKDNEODP_01065	2.66e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
MKDNEODP_01066	0.0	-	-	-	S	-	-	-	Histidine phosphatase superfamily (branch 2)
MKDNEODP_01067	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
MKDNEODP_01068	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MKDNEODP_01070	6.34e-81	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
MKDNEODP_01071	0.0	-	-	-	S	-	-	-	domain protein
MKDNEODP_01072	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MKDNEODP_01073	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MKDNEODP_01074	2.81e-164	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MKDNEODP_01075	5.65e-177	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
MKDNEODP_01076	4.85e-120	-	-	-	-	-	-	-	-
MKDNEODP_01077	9.55e-127	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MKDNEODP_01078	9.28e-118	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MKDNEODP_01079	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
MKDNEODP_01080	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
MKDNEODP_01081	1.43e-96	-	-	-	S	ko:K06889	-	ko00000	Psort location Cytoplasmic, score 8.87
MKDNEODP_01082	1.21e-22	-	-	-	L	-	-	-	Transposase DDE domain
MKDNEODP_01084	2.34e-31	-	-	-	G	-	-	-	beta-galactosidase
MKDNEODP_01086	7.25e-19	-	-	-	-	-	-	-	-
MKDNEODP_01087	3.43e-29	-	-	-	S	ko:K09803	-	ko00000	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
MKDNEODP_01088	5.46e-261	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MKDNEODP_01089	7.14e-188	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MKDNEODP_01090	4.22e-41	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKDNEODP_01091	1.74e-101	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MKDNEODP_01092	6.56e-188	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKDNEODP_01093	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MKDNEODP_01094	3.68e-204	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MKDNEODP_01095	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MKDNEODP_01096	2.55e-65	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MKDNEODP_01097	1.27e-174	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MKDNEODP_01098	1.14e-205	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
MKDNEODP_01099	3.71e-240	-	-	-	-	-	-	-	-
MKDNEODP_01100	1.44e-231	-	-	-	-	-	-	-	-
MKDNEODP_01101	1.7e-213	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
MKDNEODP_01102	9.16e-151	-	-	-	S	-	-	-	CYTH
MKDNEODP_01104	1.33e-82	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
MKDNEODP_01105	8.32e-229	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
MKDNEODP_01106	3.96e-228	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MKDNEODP_01107	1.17e-290	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MKDNEODP_01108	7.04e-267	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_01109	1.13e-202	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01110	5.75e-169	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01111	2.79e-292	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MKDNEODP_01112	9.53e-226	-	-	-	S	-	-	-	CAAX protease self-immunity
MKDNEODP_01113	1.6e-177	-	-	-	M	-	-	-	Mechanosensitive ion channel
MKDNEODP_01114	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
MKDNEODP_01115	1.56e-173	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKDNEODP_01116	1.93e-305	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MKDNEODP_01117	2.65e-110	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKDNEODP_01118	3.38e-15	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
MKDNEODP_01123	3.73e-33	yxiO	-	-	G	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Major facilitator Superfamily
MKDNEODP_01124	5.7e-15	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MKDNEODP_01125	3.04e-32	-	-	-	-	-	-	-	-
MKDNEODP_01126	1.21e-245	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKDNEODP_01127	5.42e-293	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
MKDNEODP_01128	3.78e-249	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
MKDNEODP_01129	3.03e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
MKDNEODP_01130	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
MKDNEODP_01131	6.42e-89	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
MKDNEODP_01132	3.29e-205	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01133	2.54e-220	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01134	1.37e-308	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_01135	3.09e-159	-	-	-	-	-	-	-	-
MKDNEODP_01136	4.19e-241	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MKDNEODP_01137	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MKDNEODP_01138	1.05e-95	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MKDNEODP_01139	2.64e-267	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MKDNEODP_01140	1.68e-277	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
MKDNEODP_01141	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MKDNEODP_01142	5.79e-130	-	-	-	-	-	-	-	-
MKDNEODP_01143	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
MKDNEODP_01144	1.44e-159	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MKDNEODP_01145	1.38e-189	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKDNEODP_01147	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MKDNEODP_01148	1.06e-89	-	-	-	K	-	-	-	Transcriptional regulator
MKDNEODP_01149	7.16e-118	-	-	-	S	-	-	-	Protein conserved in bacteria
MKDNEODP_01150	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
MKDNEODP_01151	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
MKDNEODP_01152	6.92e-204	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MKDNEODP_01153	4.92e-266	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MKDNEODP_01154	9.91e-302	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MKDNEODP_01156	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
MKDNEODP_01157	2.22e-238	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
MKDNEODP_01158	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MKDNEODP_01159	9.84e-237	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MKDNEODP_01160	1.17e-143	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MKDNEODP_01161	1.2e-287	tcsS3	-	-	KT	-	-	-	PspC domain
MKDNEODP_01162	4.44e-231	pspC	-	-	KT	-	-	-	PspC domain
MKDNEODP_01163	3.53e-101	-	-	-	-	-	-	-	-
MKDNEODP_01164	0.0	-	-	-	S	ko:K06889	-	ko00000	alpha beta
MKDNEODP_01165	1.34e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
MKDNEODP_01166	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
MKDNEODP_01167	0.0	-	-	-	I	-	-	-	PAP2 superfamily
MKDNEODP_01168	2.71e-262	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
MKDNEODP_01170	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MKDNEODP_01171	6.97e-216	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
MKDNEODP_01172	3.69e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MKDNEODP_01173	2.46e-147	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MKDNEODP_01174	6.48e-254	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MKDNEODP_01175	1.97e-50	-	-	-	-	-	-	-	-
MKDNEODP_01176	6.07e-274	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MKDNEODP_01177	1.85e-214	-	-	-	S	-	-	-	CHAP domain
MKDNEODP_01178	3.42e-118	-	-	-	M	-	-	-	NlpC/P60 family
MKDNEODP_01179	1.81e-137	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
MKDNEODP_01180	3.06e-238	-	-	-	T	-	-	-	Universal stress protein family
MKDNEODP_01181	9.14e-96	-	-	-	O	-	-	-	OsmC-like protein
MKDNEODP_01182	8.29e-222	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MKDNEODP_01184	6.93e-161	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
MKDNEODP_01185	2.08e-127	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
MKDNEODP_01186	1.98e-142	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKDNEODP_01187	6.2e-267	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
MKDNEODP_01188	7.23e-288	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MKDNEODP_01189	2.77e-290	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MKDNEODP_01190	1.34e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MKDNEODP_01191	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
MKDNEODP_01192	1.14e-229	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MKDNEODP_01193	1.69e-168	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MKDNEODP_01194	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKDNEODP_01195	7.09e-164	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
MKDNEODP_01196	9.02e-163	-	-	-	S	-	-	-	SNARE associated Golgi protein
MKDNEODP_01197	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
MKDNEODP_01198	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
MKDNEODP_01199	1.94e-215	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
MKDNEODP_01200	5.61e-24	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
MKDNEODP_01201	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MKDNEODP_01202	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MKDNEODP_01203	0.0	-	-	-	S	-	-	-	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MKDNEODP_01205	9.03e-200	-	-	-	S	-	-	-	AAA ATPase domain
MKDNEODP_01206	1.04e-24	-	-	-	L	-	-	-	Transposase
MKDNEODP_01207	3.74e-300	-	-	-	K	-	-	-	Putative DNA-binding domain
MKDNEODP_01208	8.3e-78	-	-	-	-	-	-	-	-
MKDNEODP_01210	2.15e-291	rfbP	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MKDNEODP_01211	2.45e-139	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
MKDNEODP_01212	5.16e-140	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MKDNEODP_01213	4.79e-210	-	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
MKDNEODP_01214	1.36e-214	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
MKDNEODP_01215	1.14e-63	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
MKDNEODP_01216	8.53e-36	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
MKDNEODP_01217	5.33e-10	-	-	-	M	-	-	-	O-antigen ligase
MKDNEODP_01218	3.78e-172	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MKDNEODP_01219	6.27e-147	-	-	-	C	-	-	-	Polysaccharide pyruvyl transferase
MKDNEODP_01220	6.22e-56	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
MKDNEODP_01222	5.01e-255	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MKDNEODP_01223	2.51e-25	-	-	-	-	-	-	-	-
MKDNEODP_01224	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MKDNEODP_01225	5.16e-217	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MKDNEODP_01227	4.71e-27	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
MKDNEODP_01228	4.67e-315	-	-	-	L	-	-	-	HTH-like domain
MKDNEODP_01229	7.38e-44	-	-	-	L	ko:K07483	-	ko00000	Transposase
MKDNEODP_01230	6.24e-184	tnp3521a2	-	-	L	-	-	-	Integrase core domain
MKDNEODP_01231	1.2e-60	-	-	-	S	-	-	-	SIR2-like domain
MKDNEODP_01232	0.0	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
MKDNEODP_01233	2.27e-64	-	-	-	L	-	-	-	Helix-turn-helix domain
MKDNEODP_01234	2.07e-33	-	-	-	-	-	-	-	-
MKDNEODP_01236	1.18e-24	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MKDNEODP_01238	8.31e-115	-	-	-	S	-	-	-	RloB-like protein
MKDNEODP_01239	5.66e-235	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
MKDNEODP_01240	3.64e-30	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
MKDNEODP_01241	8.49e-18	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
MKDNEODP_01242	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MKDNEODP_01243	2.32e-314	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
MKDNEODP_01244	2.28e-258	-	-	-	-	-	-	-	-
MKDNEODP_01245	1.35e-216	-	-	-	S	ko:K21688	-	ko00000	G5
MKDNEODP_01246	5.55e-79	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
MKDNEODP_01247	1.46e-162	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
MKDNEODP_01248	8.16e-206	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MKDNEODP_01249	3.25e-292	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
MKDNEODP_01250	1.66e-93	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MKDNEODP_01251	2.82e-39	-	-	-	L	-	-	-	Transposase
MKDNEODP_01252	0.0	intA	-	-	L	-	-	-	Phage integrase family
MKDNEODP_01253	8.73e-186	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
MKDNEODP_01254	1.53e-35	-	-	-	-	-	-	-	-
MKDNEODP_01256	3.96e-15	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
MKDNEODP_01257	1.44e-259	-	-	-	L	-	-	-	Transposase, Mutator family
MKDNEODP_01258	3.91e-46	-	-	-	D	-	-	-	Filamentation induced by cAMP protein fic
MKDNEODP_01259	5.35e-305	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_01261	6.21e-47	-	-	-	S	-	-	-	Fic/DOC family
MKDNEODP_01262	2.19e-196	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MKDNEODP_01263	1.59e-137	-	-	-	S	-	-	-	KR domain
MKDNEODP_01264	4.94e-103	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MKDNEODP_01265	6.19e-145	-	-	-	S	-	-	-	Fic/DOC family
MKDNEODP_01266	5.6e-308	-	-	-	S	-	-	-	HipA-like C-terminal domain
MKDNEODP_01268	1.53e-97	-	-	-	-	-	-	-	-
MKDNEODP_01269	5.43e-122	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MKDNEODP_01270	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MKDNEODP_01271	1.62e-106	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MKDNEODP_01272	1.42e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
MKDNEODP_01273	1.44e-236	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
MKDNEODP_01274	3.02e-298	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
MKDNEODP_01275	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
MKDNEODP_01276	1.05e-160	-	-	-	KT	-	-	-	RESPONSE REGULATOR receiver
MKDNEODP_01277	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
MKDNEODP_01278	2.92e-219	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKDNEODP_01279	1.29e-264	-	-	-	G	-	-	-	Major Facilitator Superfamily
MKDNEODP_01280	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
MKDNEODP_01281	1.03e-243	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MKDNEODP_01282	1.1e-157	-	-	-	-	-	-	-	-
MKDNEODP_01283	4.54e-243	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MKDNEODP_01284	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
MKDNEODP_01285	1.56e-166	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
MKDNEODP_01286	9.83e-110	-	-	-	-	-	-	-	-
MKDNEODP_01287	4.3e-219	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MKDNEODP_01288	3.93e-82	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MKDNEODP_01289	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MKDNEODP_01290	1.24e-154	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MKDNEODP_01291	3.06e-130	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
MKDNEODP_01292	2.91e-260	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MKDNEODP_01293	4.64e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
MKDNEODP_01294	1.06e-106	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKDNEODP_01295	2.13e-118	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MKDNEODP_01296	4.82e-151	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKDNEODP_01297	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
MKDNEODP_01298	7.92e-175	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
MKDNEODP_01299	3.56e-233	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MKDNEODP_01300	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MKDNEODP_01301	2.32e-174	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
MKDNEODP_01302	2.77e-226	-	-	-	EG	-	-	-	EamA-like transporter family
MKDNEODP_01303	2.62e-189	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MKDNEODP_01304	1.11e-152	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
MKDNEODP_01305	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
MKDNEODP_01306	1.8e-110	-	-	-	S	-	-	-	PIN domain
MKDNEODP_01307	4.99e-76	-	-	-	L	-	-	-	RelB antitoxin
MKDNEODP_01308	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MKDNEODP_01309	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
MKDNEODP_01310	2.54e-148	-	-	-	-	-	-	-	-
MKDNEODP_01311	4.96e-308	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKDNEODP_01312	2.19e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
MKDNEODP_01313	2.45e-186	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
MKDNEODP_01314	1.08e-215	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
MKDNEODP_01315	0.0	-	-	-	EP	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
MKDNEODP_01316	1.82e-229	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
MKDNEODP_01317	1.89e-202	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01318	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
MKDNEODP_01319	6.16e-238	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
MKDNEODP_01320	3.75e-57	-	-	-	-	-	-	-	-
MKDNEODP_01321	2.47e-240	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
MKDNEODP_01322	1.52e-243	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
MKDNEODP_01323	2.17e-97	-	-	-	-	-	-	-	-
MKDNEODP_01324	6.31e-46	-	-	-	L	-	-	-	PFAM Integrase catalytic
MKDNEODP_01326	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
MKDNEODP_01327	3.1e-271	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
MKDNEODP_01328	1.07e-207	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
MKDNEODP_01329	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
MKDNEODP_01330	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MKDNEODP_01331	7.49e-197	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
MKDNEODP_01332	2.14e-148	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MKDNEODP_01333	2.2e-199	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MKDNEODP_01334	8.08e-193	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
MKDNEODP_01335	2.09e-215	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
MKDNEODP_01336	7.76e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MKDNEODP_01337	1.4e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
MKDNEODP_01338	3.43e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MKDNEODP_01339	1.82e-171	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
MKDNEODP_01340	1.05e-253	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MKDNEODP_01341	5.31e-115	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MKDNEODP_01342	1.37e-227	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MKDNEODP_01343	4.72e-242	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MKDNEODP_01344	3.18e-238	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MKDNEODP_01345	6.7e-72	-	-	-	-	-	-	-	-
MKDNEODP_01346	1.54e-172	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKDNEODP_01347	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MKDNEODP_01348	1.36e-243	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
MKDNEODP_01349	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MKDNEODP_01350	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
MKDNEODP_01351	1.3e-202	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MKDNEODP_01352	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
MKDNEODP_01353	1.47e-98	-	-	-	F	-	-	-	NUDIX domain
MKDNEODP_01354	1.98e-227	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
MKDNEODP_01357	5.24e-158	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport systems inner membrane component
MKDNEODP_01358	1.18e-139	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01359	1.83e-253	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_01360	4.16e-297	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
MKDNEODP_01361	3.84e-192	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MKDNEODP_01362	6.36e-257	-	-	-	GK	-	-	-	ROK family
MKDNEODP_01363	7.17e-205	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MKDNEODP_01364	2.83e-282	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MKDNEODP_01365	1.66e-216	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MKDNEODP_01366	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
MKDNEODP_01367	8.39e-299	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
MKDNEODP_01368	3.87e-208	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MKDNEODP_01369	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKDNEODP_01370	9.32e-231	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01371	3.78e-221	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01372	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MKDNEODP_01373	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
MKDNEODP_01374	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
MKDNEODP_01375	6.8e-110	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MKDNEODP_01376	1.35e-82	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
MKDNEODP_01377	1.11e-163	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MKDNEODP_01378	7.31e-28	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MKDNEODP_01379	9.77e-35	-	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
MKDNEODP_01380	6.64e-19	-	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase
MKDNEODP_01383	9.95e-233	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MKDNEODP_01384	2.21e-157	-	-	-	L	ko:K07496	-	ko00000	Psort location Cytoplasmic, score 8.87
MKDNEODP_01385	1.73e-45	tnp3521a2	-	-	L	-	-	-	Integrase core domain
MKDNEODP_01386	1.94e-287	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MKDNEODP_01387	3.08e-244	-	-	-	L	-	-	-	Phage integrase family
MKDNEODP_01388	4.49e-259	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
MKDNEODP_01389	6.91e-45	tnp3521a2	-	-	L	-	-	-	Integrase core domain
MKDNEODP_01390	2.98e-46	-	-	-	S	ko:K09136	-	ko00000,ko03009	YcaO cyclodehydratase, ATP-ad Mg2+-binding
MKDNEODP_01391	3.46e-108	-	-	-	V	-	-	-	ABC-2 family transporter protein
MKDNEODP_01392	6.13e-138	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_01393	2.65e-185	tnp3521a2	-	-	L	-	-	-	Integrase core domain
MKDNEODP_01394	1.85e-60	-	-	-	L	ko:K07483	-	ko00000	Transposase
MKDNEODP_01396	3.4e-235	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
MKDNEODP_01397	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MKDNEODP_01398	5.23e-277	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MKDNEODP_01399	6.74e-286	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
MKDNEODP_01400	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MKDNEODP_01401	7.84e-264	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MKDNEODP_01402	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MKDNEODP_01403	5.87e-197	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MKDNEODP_01404	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
MKDNEODP_01405	2.74e-96	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MKDNEODP_01406	9.64e-249	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MKDNEODP_01407	3.86e-119	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MKDNEODP_01408	0.0	-	-	-	L	-	-	-	DNA helicase
MKDNEODP_01409	1.31e-289	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MKDNEODP_01410	1.91e-100	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MKDNEODP_01411	2.32e-70	-	-	-	M	-	-	-	Lysin motif
MKDNEODP_01412	2.78e-166	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MKDNEODP_01413	6.04e-201	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKDNEODP_01414	4.62e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MKDNEODP_01415	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MKDNEODP_01416	3.86e-157	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
MKDNEODP_01417	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
MKDNEODP_01418	4.56e-221	-	-	-	M	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MKDNEODP_01419	0.0	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKDNEODP_01420	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MKDNEODP_01421	3.25e-227	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01422	5.43e-176	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01423	4.72e-241	-	-	-	EGP	ko:K18567,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
MKDNEODP_01424	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MKDNEODP_01425	3.61e-25	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
MKDNEODP_01426	1.96e-166	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
MKDNEODP_01427	1.77e-156	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MKDNEODP_01428	4.01e-143	-	-	-	-	-	-	-	-
MKDNEODP_01429	2.75e-143	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
MKDNEODP_01430	1.1e-279	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MKDNEODP_01431	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MKDNEODP_01432	1.03e-197	-	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, N-terminal domain
MKDNEODP_01433	2.61e-197	-	-	-	S	-	-	-	Aldo/keto reductase family
MKDNEODP_01434	3.62e-249	-	-	-	S	-	-	-	Short C-terminal domain
MKDNEODP_01435	1.43e-51	-	-	-	-	-	-	-	-
MKDNEODP_01436	2.72e-285	-	-	-	-	-	-	-	-
MKDNEODP_01437	2.87e-101	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MKDNEODP_01438	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
MKDNEODP_01439	0.0	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
MKDNEODP_01440	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
MKDNEODP_01441	2.7e-17	-	-	-	-	-	-	-	-
MKDNEODP_01442	2.35e-151	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKDNEODP_01443	1.04e-273	-	-	-	G	-	-	-	Transmembrane secretion effector
MKDNEODP_01444	2.19e-309	-	-	-	S	-	-	-	HipA-like C-terminal domain
MKDNEODP_01445	5.09e-51	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MKDNEODP_01446	1.92e-67	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MKDNEODP_01447	2.26e-108	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
MKDNEODP_01448	6.44e-205	-	-	-	J	-	-	-	Methyltransferase domain
MKDNEODP_01449	7.81e-79	yccF	-	-	S	-	-	-	Inner membrane component domain
MKDNEODP_01450	3.18e-299	-	-	-	K	-	-	-	Fic/DOC family
MKDNEODP_01451	2.25e-31	-	-	-	L	-	-	-	Transposase, Mutator family
MKDNEODP_01452	0.0	-	-	-	L	-	-	-	ABC transporter
MKDNEODP_01453	4.79e-307	-	-	-	V	-	-	-	MatE
MKDNEODP_01455	2.31e-36	-	-	-	S	ko:K02890,ko:K07343	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	rRNA binding
MKDNEODP_01456	2.63e-207	tetD	-	-	K	ko:K13653	-	ko00000,ko03000	Arac family
MKDNEODP_01457	4.15e-258	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MKDNEODP_01458	6.51e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKDNEODP_01459	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
MKDNEODP_01460	0.0	-	-	-	T	-	-	-	Histidine kinase
MKDNEODP_01461	5.96e-182	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MKDNEODP_01462	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MKDNEODP_01463	8.85e-184	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKDNEODP_01464	9.49e-317	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
MKDNEODP_01465	3.75e-209	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
MKDNEODP_01466	3.62e-121	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
MKDNEODP_01467	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
MKDNEODP_01468	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
MKDNEODP_01469	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
MKDNEODP_01470	7.19e-234	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
MKDNEODP_01471	2.45e-141	safC	-	-	S	-	-	-	O-methyltransferase
MKDNEODP_01472	9.06e-208	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MKDNEODP_01473	1.54e-306	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MKDNEODP_01476	3.4e-311	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MKDNEODP_01477	1.81e-158	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MKDNEODP_01478	4.2e-151	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MKDNEODP_01479	2.82e-78	-	-	-	-	-	-	-	-
MKDNEODP_01480	3e-299	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
MKDNEODP_01481	4.94e-304	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MKDNEODP_01482	9.6e-317	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
MKDNEODP_01483	5.5e-154	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
MKDNEODP_01484	1.49e-221	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MKDNEODP_01485	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
MKDNEODP_01486	9.66e-46	-	-	-	-	-	-	-	-
MKDNEODP_01487	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MKDNEODP_01488	1.64e-284	-	-	-	S	-	-	-	Peptidase dimerisation domain
MKDNEODP_01489	1.12e-145	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01490	1.5e-276	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKDNEODP_01491	1.22e-223	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
MKDNEODP_01492	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MKDNEODP_01493	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MKDNEODP_01494	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
MKDNEODP_01495	1.59e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKDNEODP_01497	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MKDNEODP_01498	5.2e-82	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MKDNEODP_01499	2.28e-156	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
MKDNEODP_01502	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
MKDNEODP_01503	2.87e-289	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKDNEODP_01504	6.91e-315	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MKDNEODP_01505	1.58e-249	-	-	-	-	-	-	-	-
MKDNEODP_01508	1.21e-18	-	-	-	K	-	-	-	Putative zinc ribbon domain
MKDNEODP_01509	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
MKDNEODP_01510	2.32e-161	-	-	-	L	-	-	-	NUDIX domain
MKDNEODP_01511	3.98e-228	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
MKDNEODP_01512	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKDNEODP_01513	3.04e-164	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
MKDNEODP_01515	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
MKDNEODP_01516	1.09e-227	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
MKDNEODP_01517	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MKDNEODP_01518	9.26e-69	-	-	-	T	-	-	-	Histidine kinase
MKDNEODP_01519	1.06e-80	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MKDNEODP_01520	4.91e-177	XK27_10205	-	-	-	ko:K02004	-	ko00000,ko00002,ko02000	-
MKDNEODP_01521	4.34e-95	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MKDNEODP_01522	1.79e-93	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MKDNEODP_01523	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MKDNEODP_01524	9.81e-201	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MKDNEODP_01525	2.9e-258	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
MKDNEODP_01526	5.11e-210	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_01527	6.66e-176	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
MKDNEODP_01528	9.43e-116	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MKDNEODP_01529	1.85e-131	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
MKDNEODP_01530	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MKDNEODP_01531	8.63e-165	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
MKDNEODP_01532	2.36e-248	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MKDNEODP_01533	2.22e-85	umuD	-	-	KT	ko:K03503	-	ko00000,ko01000,ko01002,ko03400	Peptidase S24-like
MKDNEODP_01534	2.41e-71	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
MKDNEODP_01535	1.29e-193	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
MKDNEODP_01536	3.82e-95	-	-	-	S	-	-	-	Zincin-like metallopeptidase
MKDNEODP_01537	0.0	-	-	-	-	-	-	-	-
MKDNEODP_01538	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
MKDNEODP_01539	7.16e-75	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MKDNEODP_01540	7.26e-207	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
MKDNEODP_01541	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
MKDNEODP_01542	3.32e-61	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MKDNEODP_01543	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
MKDNEODP_01544	7.85e-175	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
MKDNEODP_01545	7.1e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MKDNEODP_01546	5.53e-96	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
MKDNEODP_01547	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
MKDNEODP_01548	1.35e-120	-	-	-	-	-	-	-	-
MKDNEODP_01550	9.72e-229	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
MKDNEODP_01551	1.61e-132	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
MKDNEODP_01552	9.56e-103	-	-	-	D	-	-	-	Septum formation initiator
MKDNEODP_01553	3.54e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MKDNEODP_01554	2.62e-220	-	-	-	C	-	-	-	Aldo/keto reductase family
MKDNEODP_01555	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MKDNEODP_01556	4.23e-147	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MKDNEODP_01557	2.11e-93	-	-	-	S	-	-	-	PIN domain
MKDNEODP_01558	3.89e-62	-	-	-	S	-	-	-	RelB antitoxin
MKDNEODP_01559	3.22e-114	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
MKDNEODP_01560	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
MKDNEODP_01561	7.51e-265	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
MKDNEODP_01562	5.62e-176	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MKDNEODP_01563	6.47e-130	-	-	-	-	-	-	-	-
MKDNEODP_01564	7.42e-294	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MKDNEODP_01565	0.0	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MKDNEODP_01566	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
MKDNEODP_01567	1.36e-250	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
MKDNEODP_01568	2e-98	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
MKDNEODP_01569	8.18e-293	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MKDNEODP_01570	1.24e-52	pacL2	3.6.3.8	-	P	ko:K01537,ko:K12955	-	ko00000,ko01000	ATPase, P-type transporting, HAD superfamily, subfamily IC
MKDNEODP_01571	2.8e-91	-	-	-	S	-	-	-	ABC-2 family transporter protein
MKDNEODP_01572	1.94e-155	-	-	-	S	-	-	-	ABC-2 family transporter protein
MKDNEODP_01573	1.32e-222	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_01574	3.46e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
MKDNEODP_01575	1.27e-75	-	-	-	EGP	-	-	-	Major facilitator Superfamily
MKDNEODP_01577	1.51e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MKDNEODP_01578	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MKDNEODP_01579	8.22e-246	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MKDNEODP_01580	1.12e-125	-	-	-	-	-	-	-	-
MKDNEODP_01581	2.37e-175	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MKDNEODP_01583	1.22e-249	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
MKDNEODP_01584	5.54e-213	-	-	-	L	-	-	-	Tetratricopeptide repeat
MKDNEODP_01585	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MKDNEODP_01586	1.67e-174	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MKDNEODP_01587	1.24e-126	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MKDNEODP_01588	1.76e-73	-	-	-	P	-	-	-	Rhodanese Homology Domain
MKDNEODP_01589	1.19e-190	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
MKDNEODP_01590	1.19e-200	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MKDNEODP_01591	5.04e-39	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
MKDNEODP_01592	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MKDNEODP_01593	4.9e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MKDNEODP_01594	4.34e-110	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MKDNEODP_01595	7.19e-234	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MKDNEODP_01596	9.37e-313	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
MKDNEODP_01597	3.68e-212	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MKDNEODP_01598	7.94e-271	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MKDNEODP_01599	1.02e-257	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MKDNEODP_01600	3.07e-143	-	-	-	-	-	-	-	-
MKDNEODP_01601	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
MKDNEODP_01602	1.83e-258	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MKDNEODP_01603	9.21e-211	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKDNEODP_01604	9.39e-191	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MKDNEODP_01605	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_01606	7.57e-141	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MKDNEODP_01607	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
MKDNEODP_01608	1.1e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
MKDNEODP_01609	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MKDNEODP_01610	7.35e-176	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
MKDNEODP_01611	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MKDNEODP_01612	4.08e-107	-	3.2.1.23, 3.2.1.31	-	G	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolases family 2, TIM barrel domain
MKDNEODP_01613	4.25e-233	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MKDNEODP_01614	9.16e-99	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MKDNEODP_01615	3.36e-108	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MKDNEODP_01617	1.7e-150	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
MKDNEODP_01618	8.96e-308	-	-	-	V	-	-	-	MatE
MKDNEODP_01619	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MKDNEODP_01620	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
MKDNEODP_01621	2.79e-38	-	-	-	S	-	-	-	Domain of unknown function (DUF4913)
MKDNEODP_01622	1.04e-92	istB	-	-	L	-	-	-	IstB-like ATP binding protein
MKDNEODP_01623	1.73e-60	-	-	-	L	-	-	-	PFAM Integrase catalytic
MKDNEODP_01624	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MKDNEODP_01625	1.33e-160	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MKDNEODP_01626	1.4e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKDNEODP_01627	4.16e-44	-	-	-	S	ko:K07133	-	ko00000	AAA domain
MKDNEODP_01628	7.11e-172	-	-	-	C	-	-	-	FMN binding
MKDNEODP_01629	3e-124	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MKDNEODP_01630	5.1e-07	-	-	-	K	-	-	-	MerR, DNA binding
MKDNEODP_01631	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MKDNEODP_01632	2.35e-243	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
MKDNEODP_01633	2.34e-21	-	-	-	K	-	-	-	MerR family regulatory protein
MKDNEODP_01634	8.54e-24	-	-	-	K	-	-	-	MerR family regulatory protein
MKDNEODP_01635	1.43e-112	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKDNEODP_01636	5.59e-78	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKDNEODP_01637	8.44e-39	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MKDNEODP_01638	1.69e-235	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MKDNEODP_01639	1.49e-185	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
MKDNEODP_01640	1.17e-127	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
MKDNEODP_01641	3.37e-292	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MKDNEODP_01642	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MKDNEODP_01643	1.9e-104	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MKDNEODP_01644	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MKDNEODP_01646	2.07e-240	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
MKDNEODP_01648	2.18e-245	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
MKDNEODP_01649	2.78e-273	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
MKDNEODP_01650	1.26e-240	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MKDNEODP_01651	3.37e-296	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MKDNEODP_01652	4.25e-82	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKDNEODP_01653	9.74e-176	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MKDNEODP_01654	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
MKDNEODP_01655	2.5e-235	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MKDNEODP_01656	0.0	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
MKDNEODP_01657	7.04e-140	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
MKDNEODP_01658	9.34e-130	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
MKDNEODP_01659	1.51e-215	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain
MKDNEODP_01660	5.22e-13	-	-	-	C	-	-	-	Aldo/keto reductase family
MKDNEODP_01661	4.32e-58	-	-	-	C	-	-	-	Aldo/keto reductase family
MKDNEODP_01662	9.47e-43	-	-	-	-	-	-	-	-
MKDNEODP_01663	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
MKDNEODP_01664	2.49e-243	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	S-adenosyl-L-homocysteine hydrolase, NAD binding domain
MKDNEODP_01665	1.91e-301	-	-	-	F	-	-	-	Amidohydrolase family
MKDNEODP_01666	7.06e-86	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
MKDNEODP_01667	6.76e-163	-	-	-	ET	ko:K02030,ko:K02424,ko:K17073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Bacterial periplasmic substrate-binding proteins
MKDNEODP_01668	3.2e-161	-	-	-	E	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01669	2.57e-153	-	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MKDNEODP_01670	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MKDNEODP_01671	6.44e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MKDNEODP_01672	1.15e-297	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MKDNEODP_01673	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
MKDNEODP_01674	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
MKDNEODP_01675	9.67e-200	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
MKDNEODP_01676	1.13e-127	-	-	-	S	-	-	-	cobalamin synthesis protein
MKDNEODP_01677	8.31e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
MKDNEODP_01678	5.79e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
MKDNEODP_01679	1.24e-58	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKDNEODP_01680	1.72e-45	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MKDNEODP_01681	4.34e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
MKDNEODP_01682	1.55e-27	-	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal L32p protein family
MKDNEODP_01683	1.17e-23	-	-	-	P	ko:K02077,ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MKDNEODP_01684	1.89e-254	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
MKDNEODP_01685	2.69e-178	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
MKDNEODP_01686	8.39e-73	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Ferric uptake regulator family
MKDNEODP_01687	3.43e-85	-	-	-	-	-	-	-	-
MKDNEODP_01688	6.6e-58	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
MKDNEODP_01689	5.88e-90	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MKDNEODP_01691	2.45e-59	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MKDNEODP_01692	7.7e-95	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MKDNEODP_01693	4.92e-286	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MKDNEODP_01694	8.44e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MKDNEODP_01695	6.77e-223	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
MKDNEODP_01696	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MKDNEODP_01697	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MKDNEODP_01698	4.06e-185	-	-	-	M	-	-	-	Conserved repeat domain
MKDNEODP_01699	3.61e-157	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_01702	5.97e-267	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MKDNEODP_01703	8.77e-203	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MKDNEODP_01704	0.0	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminal domain
MKDNEODP_01705	1.47e-48	-	-	-	-	-	-	-	-
MKDNEODP_01706	2.61e-19	-	-	-	P	-	-	-	Citrate transporter
MKDNEODP_01707	0.0	-	-	-	EK	ko:K03710,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000,ko03000	Alanine-glyoxylate amino-transferase
MKDNEODP_01708	4.17e-149	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MKDNEODP_01709	1.9e-198	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MKDNEODP_01710	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MKDNEODP_01711	4.87e-313	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
MKDNEODP_01712	2.12e-315	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKDNEODP_01713	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
MKDNEODP_01714	1.45e-131	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKDNEODP_01715	2.77e-119	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MKDNEODP_01716	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MKDNEODP_01717	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
MKDNEODP_01718	1.84e-282	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
MKDNEODP_01719	1.17e-118	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
MKDNEODP_01720	0.000141	-	-	-	F	-	-	-	Amidohydrolase family
MKDNEODP_01721	7.91e-225	-	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
MKDNEODP_01722	8.01e-193	iunH2	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
MKDNEODP_01724	3.28e-154	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
MKDNEODP_01725	1.71e-180	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01726	1.38e-206	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01727	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
MKDNEODP_01728	1.38e-308	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MKDNEODP_01729	4.65e-181	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MKDNEODP_01730	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_01731	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
MKDNEODP_01732	7.33e-143	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
MKDNEODP_01733	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MKDNEODP_01734	2.91e-190	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_01735	2.85e-218	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01736	6.22e-216	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
MKDNEODP_01737	1.4e-213	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
MKDNEODP_01738	8.01e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MKDNEODP_01739	5.86e-263	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
MKDNEODP_01740	3.68e-204	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
MKDNEODP_01741	2.61e-234	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
MKDNEODP_01742	3.59e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MKDNEODP_01743	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
MKDNEODP_01744	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MKDNEODP_01745	1.07e-158	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MKDNEODP_01746	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MKDNEODP_01747	4.07e-131	-	-	-	P	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01748	7.79e-124	-	-	-	G	ko:K02026,ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01749	2.99e-200	-	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_01750	2.94e-126	-	-	-	C	-	-	-	Domain of unknown function
MKDNEODP_01751	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
MKDNEODP_01752	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKDNEODP_01753	8.94e-213	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MKDNEODP_01754	1.26e-167	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MKDNEODP_01755	6.14e-297	-	-	-	G	-	-	-	Major Facilitator Superfamily
MKDNEODP_01756	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
MKDNEODP_01757	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
MKDNEODP_01758	0.0	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MKDNEODP_01759	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
MKDNEODP_01760	3.15e-233	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
MKDNEODP_01761	2.52e-282	-	-	-	S	-	-	-	Protein of unknown function DUF58
MKDNEODP_01762	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
MKDNEODP_01763	1.54e-05	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
MKDNEODP_01764	1.05e-31	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
MKDNEODP_01765	1.44e-100	-	-	-	B	-	-	-	Belongs to the OprB family
MKDNEODP_01766	8.85e-117	-	-	-	T	-	-	-	Forkhead associated domain
MKDNEODP_01767	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKDNEODP_01768	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKDNEODP_01769	2.14e-149	-	-	-	-	-	-	-	-
MKDNEODP_01770	2.52e-235	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
MKDNEODP_01771	9.47e-149	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MKDNEODP_01772	3.82e-52	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	ParE toxin of type II toxin-antitoxin system, parDE
MKDNEODP_01773	1.28e-45	-	-	-	S	ko:K18918	-	ko00000,ko02048,ko03000	CopG domain protein DNA-binding domain protein
MKDNEODP_01775	1.27e-24	-	-	-	Q	-	-	-	Belongs to the P-Pant transferase superfamily
MKDNEODP_01776	3.38e-159	-	-	-	U	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
MKDNEODP_01777	2.08e-284	-	-	-	M	-	-	-	Belongs to the D-alanine--D-alanine ligase family
MKDNEODP_01778	1.68e-26	-	-	-	Q	-	-	-	COG1020 Non-ribosomal peptide synthetase modules and related proteins
MKDNEODP_01779	1.25e-41	-	-	-	Q	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	Non-ribosomal peptide synthetase modules and related proteins
MKDNEODP_01780	8.02e-277	-	-	-	P	-	-	-	Major Facilitator Superfamily
MKDNEODP_01781	5.65e-51	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
MKDNEODP_01782	7.8e-29	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
MKDNEODP_01783	4.31e-168	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
MKDNEODP_01784	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MKDNEODP_01785	1.13e-58	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
MKDNEODP_01786	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MKDNEODP_01787	9.48e-242	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MKDNEODP_01788	3.11e-130	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MKDNEODP_01789	2.26e-216	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01790	1.14e-218	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_01791	2.67e-111	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_01792	5.28e-204	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_01793	1.65e-267	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Drug resistance MFS transporter, drug H antiporter-2 family
MKDNEODP_01794	2.92e-297	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
MKDNEODP_01795	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
MKDNEODP_01796	1.03e-157	-	-	-	K	-	-	-	DeoR C terminal sensor domain
MKDNEODP_01797	1.71e-286	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MKDNEODP_01798	9.1e-317	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
MKDNEODP_01799	0.0	pon1	-	-	M	-	-	-	Transglycosylase
MKDNEODP_01800	1.23e-168	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
MKDNEODP_01801	2.12e-253	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
MKDNEODP_01802	3.1e-246	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MKDNEODP_01803	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
MKDNEODP_01804	0.0	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
MKDNEODP_01805	5.99e-274	-	-	-	L	ko:K07496	-	ko00000	Helix-turn-helix domain
MKDNEODP_01806	1.12e-131	-	-	-	L	ko:K07450	-	ko00000	Resolvase, N terminal domain
MKDNEODP_01807	9.48e-237	-	-	-	V	-	-	-	Abi-like protein
MKDNEODP_01808	1.77e-177	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MKDNEODP_01809	4.57e-11	-	-	-	L	-	-	-	Transposase, Mutator family
MKDNEODP_01811	1.05e-07	-	-	-	-	-	-	-	-
MKDNEODP_01813	1.71e-42	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
MKDNEODP_01814	1.43e-96	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
MKDNEODP_01815	6.99e-31	-	-	-	D	-	-	-	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MKDNEODP_01816	2.25e-192	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MKDNEODP_01817	2.44e-134	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_01818	4.49e-145	-	-	-	-	-	-	-	-
MKDNEODP_01819	4.19e-155	-	-	-	-	-	-	-	-
MKDNEODP_01820	1.81e-30	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MKDNEODP_01821	3.66e-114	mutF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter ATP-binding
MKDNEODP_01822	1.28e-76	mutE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MKDNEODP_01823	1.88e-73	mutG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	Lantibiotic protection ABC transporter permease subunit, MutG family
MKDNEODP_01824	1.13e-113	-	-	-	-	ko:K20489	ko02020,ko02024,map02020,map02024	ko00000,ko00001	-
MKDNEODP_01825	2.79e-126	-	-	-	T	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MKDNEODP_01826	7.61e-145	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	subtilin biosynthesis sensor protein SpaK
MKDNEODP_01827	1.59e-129	-	-	-	-	-	-	-	-
MKDNEODP_01828	8.67e-205	-	-	-	EG	-	-	-	EamA-like transporter family
MKDNEODP_01829	3.34e-92	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
MKDNEODP_01830	7.16e-297	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
MKDNEODP_01831	1.31e-209	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
MKDNEODP_01832	1.16e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MKDNEODP_01833	1.56e-192	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MKDNEODP_01834	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MKDNEODP_01835	1.05e-98	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
MKDNEODP_01836	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
MKDNEODP_01837	2.48e-226	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MKDNEODP_01838	9.29e-132	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
MKDNEODP_01839	1.29e-191	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
MKDNEODP_01840	1.52e-127	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
MKDNEODP_01841	7.64e-249	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MKDNEODP_01844	2.35e-95	-	-	-	-	-	-	-	-
MKDNEODP_01845	1.01e-199	-	-	-	S	-	-	-	Putative amidase domain
MKDNEODP_01846	4.88e-181	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MKDNEODP_01847	4.98e-213	-	-	-	K	-	-	-	Transposase IS116 IS110 IS902
MKDNEODP_01848	4.9e-27	-	-	-	S	-	-	-	SdpI/YhfL protein family
MKDNEODP_01851	1.29e-45	-	-	-	I	-	-	-	radical SAM domain protein
MKDNEODP_01854	2e-120	-	-	-	V	ko:K06147	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_01855	2.11e-80	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
MKDNEODP_01856	1.4e-26	-	-	-	L	-	-	-	Phage integrase family
MKDNEODP_01860	1.86e-72	-	-	-	S	-	-	-	Fic/DOC family
MKDNEODP_01862	8.36e-14	-	-	-	-	-	-	-	-
MKDNEODP_01863	1.7e-46	-	-	-	-	-	-	-	-
MKDNEODP_01864	3.52e-221	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MKDNEODP_01865	3.1e-57	-	-	-	L	-	-	-	PFAM Relaxase mobilization nuclease family protein
MKDNEODP_01866	1.55e-252	-	-	-	V	ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MKDNEODP_01867	2.53e-181	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MKDNEODP_01868	6.95e-183	-	-	-	-	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
MKDNEODP_01869	3.84e-91	-	-	-	-	-	-	-	-
MKDNEODP_01871	4.55e-303	-	-	-	T	-	-	-	Histidine kinase
MKDNEODP_01872	5.21e-155	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MKDNEODP_01874	1.44e-137	-	-	-	M	-	-	-	Peptidase family M23
MKDNEODP_01875	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
MKDNEODP_01876	1.11e-305	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
MKDNEODP_01877	1.07e-264	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
MKDNEODP_01878	1.98e-91	-	-	-	-	-	-	-	-
MKDNEODP_01879	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
MKDNEODP_01880	4.26e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MKDNEODP_01881	1.37e-186	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MKDNEODP_01882	2.17e-184	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MKDNEODP_01883	4.09e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MKDNEODP_01884	1.86e-115	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MKDNEODP_01885	1.03e-216	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
MKDNEODP_01886	7.52e-284	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MKDNEODP_01887	3.87e-96	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MKDNEODP_01888	5.87e-180	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MKDNEODP_01889	2.31e-91	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MKDNEODP_01890	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKDNEODP_01891	8.02e-144	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MKDNEODP_01892	2.6e-209	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
MKDNEODP_01893	7.79e-153	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
MKDNEODP_01894	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MKDNEODP_01895	1.44e-165	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
MKDNEODP_01896	1.47e-207	-	-	-	S	-	-	-	Protein conserved in bacteria
MKDNEODP_01897	6.76e-84	-	-	-	S	-	-	-	Zincin-like metallopeptidase
MKDNEODP_01898	1.49e-41	-	-	-	G	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_01899	1.22e-17	-	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Hypothetical bacterial integral membrane protein (Trep_Strep)
MKDNEODP_01900	4.88e-152	-	2.7.13.3	-	T	ko:K18351	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MKDNEODP_01901	2.48e-149	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
MKDNEODP_01902	2.39e-187	-	-	-	-	-	-	-	-
MKDNEODP_01903	1.15e-187	-	-	-	M	-	-	-	Putative peptidoglycan binding domain
MKDNEODP_01904	2.58e-177	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_01905	2.08e-207	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MKDNEODP_01906	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MKDNEODP_01907	5.2e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
MKDNEODP_01908	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MKDNEODP_01909	2.42e-16	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MKDNEODP_01910	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MKDNEODP_01911	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MKDNEODP_01912	2.62e-237	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
MKDNEODP_01913	1.29e-235	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MKDNEODP_01914	1.42e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MKDNEODP_01915	1.84e-281	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
MKDNEODP_01916	7.71e-186	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MKDNEODP_01917	2.51e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
MKDNEODP_01918	3.95e-224	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MKDNEODP_01919	2.17e-209	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MKDNEODP_01920	7.96e-317	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
MKDNEODP_01921	2.16e-276	-	-	-	V	-	-	-	MatE
MKDNEODP_01922	2.15e-272	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MKDNEODP_01923	3.03e-256	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MKDNEODP_01924	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
MKDNEODP_01925	4.28e-238	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MKDNEODP_01926	3.8e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MKDNEODP_01927	1.07e-199	-	-	-	G	-	-	-	Fructosamine kinase
MKDNEODP_01928	1.14e-196	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MKDNEODP_01929	8.61e-206	-	-	-	S	-	-	-	PAC2 family
MKDNEODP_01935	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKDNEODP_01936	5.37e-143	-	2.7.7.53	-	FG	ko:K19710	ko00230,map00230	ko00000,ko00001,ko01000	HIT domain
MKDNEODP_01937	3.41e-156	yebC	-	-	K	-	-	-	transcriptional regulatory protein
MKDNEODP_01938	1.58e-126	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MKDNEODP_01939	4.97e-114	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MKDNEODP_01940	3.32e-242	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MKDNEODP_01941	4.71e-51	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
MKDNEODP_01942	3.96e-115	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MKDNEODP_01943	4.58e-270	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MKDNEODP_01944	2.48e-200	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MKDNEODP_01945	1.97e-310	-	-	-	-	-	-	-	-
MKDNEODP_01946	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MKDNEODP_01947	1.69e-41	-	-	-	-	-	-	-	-
MKDNEODP_01948	6.05e-206	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MKDNEODP_01949	1.29e-183	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MKDNEODP_01950	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MKDNEODP_01952	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MKDNEODP_01953	0.0	-	-	-	K	-	-	-	WYL domain
MKDNEODP_01954	7.59e-64	-	-	-	-	-	-	-	-
MKDNEODP_01955	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
MKDNEODP_01956	6.43e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
MKDNEODP_01957	1.96e-165	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
MKDNEODP_01958	3.46e-50	-	-	-	-	-	-	-	-
MKDNEODP_01959	8.45e-96	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MKDNEODP_01961	3.63e-99	-	-	-	S	-	-	-	N-methyltransferase activity
MKDNEODP_01962	4.85e-42	-	-	-	L	-	-	-	Transposase
MKDNEODP_01965	2.65e-30	hipA	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain protein
MKDNEODP_01967	2.05e-164	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MKDNEODP_01969	2.34e-56	hrtA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MKDNEODP_01971	2.66e-74	-	-	-	-	-	-	-	-
MKDNEODP_01972	6.65e-145	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MKDNEODP_01973	1.17e-96	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
MKDNEODP_01974	1.03e-177	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
MKDNEODP_01975	7.03e-51	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
MKDNEODP_01976	1.5e-196	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
MKDNEODP_01977	7.77e-137	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKDNEODP_01978	1.84e-201	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
MKDNEODP_01979	3.56e-56	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
MKDNEODP_01980	4.64e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
MKDNEODP_01981	4.02e-237	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MKDNEODP_01982	7.76e-202	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MKDNEODP_01983	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MKDNEODP_01984	1.84e-170	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
MKDNEODP_01985	1.51e-198	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MKDNEODP_01986	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
MKDNEODP_01987	3.21e-111	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_01988	1.47e-241	-	-	-	V	-	-	-	VanZ like family
MKDNEODP_01989	4.21e-63	cefD	5.1.1.17	-	E	ko:K04127	ko00311,ko01100,ko01130,map00311,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Aminotransferase, class V
MKDNEODP_01990	7.82e-118	-	-	-	K	-	-	-	FR47-like protein
MKDNEODP_01991	2.03e-33	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
MKDNEODP_01992	6.4e-129	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MKDNEODP_01993	3.82e-36	-	-	-	L	-	-	-	Transposase DDE domain
MKDNEODP_01994	0.0	-	-	-	E	ko:K03307	-	ko00000	Sodium:solute symporter family
MKDNEODP_01995	9.29e-57	-	-	-	-	-	-	-	-
MKDNEODP_01996	4.94e-109	-	-	-	G	ko:K02445,ko:K03762	-	ko00000,ko02000	transmembrane transporter activity
MKDNEODP_01997	2.1e-09	truD	5.4.99.27	-	J	ko:K06176	-	ko00000,ko01000,ko03016	Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs
MKDNEODP_01998	3.1e-59	-	-	-	L	-	-	-	Transposase DDE domain
MKDNEODP_01999	3.52e-61	-	-	-	-	-	-	-	-
MKDNEODP_02000	1.39e-155	-	-	-	-	-	-	-	-
MKDNEODP_02003	3.05e-61	-	-	-	T	-	-	-	Histidine kinase
MKDNEODP_02004	1.82e-258	-	-	-	T	-	-	-	Histidine kinase
MKDNEODP_02005	3.69e-166	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MKDNEODP_02006	5.1e-125	-	-	-	-	-	-	-	-
MKDNEODP_02007	4.14e-200	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKDNEODP_02008	1.75e-157	-	-	-	Q	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_02009	3.18e-234	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MKDNEODP_02010	1.49e-53	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MKDNEODP_02011	2.98e-64	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
MKDNEODP_02012	6.23e-35	-	-	-	G	-	-	-	Transporter major facilitator family protein
MKDNEODP_02013	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
MKDNEODP_02016	2.54e-266	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MKDNEODP_02017	1.1e-190	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKDNEODP_02018	1.23e-188	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MKDNEODP_02019	6.79e-79	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MKDNEODP_02020	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_02021	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_02022	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MKDNEODP_02025	3.33e-220	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
MKDNEODP_02026	5.57e-307	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
MKDNEODP_02027	3.97e-312	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
MKDNEODP_02028	4.58e-288	-	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Psort location Cytoplasmic, score 8.87
MKDNEODP_02030	2.87e-169	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MKDNEODP_02031	2.22e-185	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MKDNEODP_02032	5.53e-206	-	-	-	-	-	-	-	-
MKDNEODP_02033	1.4e-314	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MKDNEODP_02034	1.71e-155	-	-	-	-	-	-	-	-
MKDNEODP_02035	7.11e-91	-	-	-	K	-	-	-	MerR, DNA binding
MKDNEODP_02036	4.06e-243	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
MKDNEODP_02037	3.9e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
MKDNEODP_02038	2.45e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MKDNEODP_02039	5.73e-175	-	-	-	-	-	-	-	-
MKDNEODP_02040	8.82e-154	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MKDNEODP_02041	3.14e-42	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MKDNEODP_02042	5.2e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MKDNEODP_02043	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
MKDNEODP_02044	5.15e-118	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
MKDNEODP_02045	3.08e-57	-	-	-	S	ko:K21495	-	ko00000,ko02048	Plasmid stability protein
MKDNEODP_02046	9.76e-83	vapC	-	-	S	ko:K07062	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module. An RNase
MKDNEODP_02047	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
MKDNEODP_02048	1.07e-174	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
MKDNEODP_02049	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MKDNEODP_02050	4.51e-207	-	-	-	P	-	-	-	Cation efflux family
MKDNEODP_02051	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MKDNEODP_02052	8.12e-230	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
MKDNEODP_02053	1.76e-104	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MKDNEODP_02054	5.44e-299	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MKDNEODP_02055	2.51e-144	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Lumazine binding domain
MKDNEODP_02056	1.79e-268	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKDNEODP_02057	0.0	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000,ko01007	chorismate binding enzyme
MKDNEODP_02058	1.28e-183	pabC	2.6.1.42, 2.6.1.85, 4.1.3.38	-	E	ko:K00826,ko:K01665,ko:K02619,ko:K03342	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	branched-chain-amino-acid transaminase activity
MKDNEODP_02059	1.66e-83	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MKDNEODP_02060	1.24e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MKDNEODP_02061	9.5e-142	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MKDNEODP_02062	3.36e-61	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKDNEODP_02063	3.61e-226	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	Pfam:HipA_N
MKDNEODP_02064	3.74e-276	-	-	-	-	-	-	-	-
MKDNEODP_02065	7.48e-143	-	-	-	U	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_02066	6.88e-152	-	-	-	U	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_02067	1.61e-176	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_02068	2.08e-153	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
MKDNEODP_02069	4.43e-250	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
MKDNEODP_02070	4.08e-216	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
MKDNEODP_02071	1.32e-24	-	-	-	-	-	-	-	-
MKDNEODP_02072	4.95e-210	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MKDNEODP_02073	1.1e-16	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MKDNEODP_02074	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MKDNEODP_02075	1.03e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MKDNEODP_02076	3.17e-190	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKDNEODP_02077	2.32e-215	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
MKDNEODP_02078	3.53e-207	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MKDNEODP_02079	1.09e-238	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
MKDNEODP_02080	1.68e-179	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MKDNEODP_02081	1.89e-258	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
MKDNEODP_02082	2.91e-294	-	-	-	EGP	-	-	-	Sugar (and other) transporter
MKDNEODP_02083	5.79e-157	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MKDNEODP_02084	6.38e-298	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MKDNEODP_02085	1.27e-269	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MKDNEODP_02086	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MKDNEODP_02087	7.13e-155	-	-	-	D	-	-	-	nuclear chromosome segregation
MKDNEODP_02088	1.97e-158	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MKDNEODP_02089	2.62e-205	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MKDNEODP_02090	5.04e-232	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
MKDNEODP_02091	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
MKDNEODP_02092	4.51e-196	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MKDNEODP_02093	3.17e-135	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
MKDNEODP_02094	6.25e-74	-	-	-	L	-	-	-	Transposase DDE domain
MKDNEODP_02096	1.98e-34	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
MKDNEODP_02098	2.19e-250	-	-	-	G	-	-	-	Hypothetical glycosyl hydrolase 6
MKDNEODP_02099	7.62e-126	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
MKDNEODP_02100	1.08e-27	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
MKDNEODP_02101	1.03e-60	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
MKDNEODP_02102	1.07e-204	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKDNEODP_02103	5.99e-219	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_02104	6.64e-205	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKDNEODP_02105	5.07e-18	-	-	-	L	-	-	-	Integrase core domain
MKDNEODP_02107	6e-275	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score
MKDNEODP_02108	2.82e-192	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
MKDNEODP_02109	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
MKDNEODP_02110	4.75e-214	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MKDNEODP_02111	1.83e-86	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MKDNEODP_02112	4.01e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKDNEODP_02113	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MKDNEODP_02114	1.16e-81	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MKDNEODP_02115	1.47e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MKDNEODP_02116	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MKDNEODP_02117	7.36e-128	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MKDNEODP_02118	1.87e-316	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MKDNEODP_02119	1.52e-98	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MKDNEODP_02120	4.64e-36	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
MKDNEODP_02121	2.82e-128	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MKDNEODP_02122	3.43e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MKDNEODP_02123	7.72e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MKDNEODP_02124	3.17e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MKDNEODP_02125	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKDNEODP_02126	2.77e-134	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MKDNEODP_02127	1.09e-68	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MKDNEODP_02128	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MKDNEODP_02129	1.11e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MKDNEODP_02130	1.97e-49	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MKDNEODP_02131	3.85e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MKDNEODP_02132	1.32e-161	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MKDNEODP_02133	1.55e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MKDNEODP_02134	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MKDNEODP_02135	1.34e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MKDNEODP_02136	8.86e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MKDNEODP_02137	1.97e-150	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MKDNEODP_02138	1.57e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MKDNEODP_02139	9.35e-68	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MKDNEODP_02140	1.4e-190	-	-	-	S	-	-	-	YwiC-like protein
MKDNEODP_02141	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MKDNEODP_02142	6.5e-280	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
MKDNEODP_02144	3.56e-174	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MKDNEODP_02145	1.31e-244	-	1.1.1.9	-	C	ko:K05351	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
MKDNEODP_02146	1.9e-275	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_02147	9.69e-87	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKDNEODP_02148	1.1e-283	csbX	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_02149	1.53e-221	-	1.1.1.1, 1.1.1.287, 1.6.5.5	-	C	ko:K00001,ko:K00344,ko:K17818	ko00010,ko00040,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
MKDNEODP_02150	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
MKDNEODP_02151	9.6e-106	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MKDNEODP_02152	3.75e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MKDNEODP_02153	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
MKDNEODP_02154	3.49e-147	-	-	-	-	-	-	-	-
MKDNEODP_02155	5.2e-139	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
MKDNEODP_02156	3.58e-238	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKDNEODP_02159	3.34e-298	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKDNEODP_02160	4.38e-285	dapC	-	-	E	-	-	-	Aminotransferase class I and II
MKDNEODP_02161	1.57e-79	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
MKDNEODP_02162	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
MKDNEODP_02163	1.17e-287	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MKDNEODP_02164	1.03e-34	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
MKDNEODP_02168	2.94e-51	megL	4.4.1.11	-	E	ko:K01761	ko00270,ko00450,map00270,map00450	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
MKDNEODP_02169	6.02e-64	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MKDNEODP_02170	6.02e-277	-	-	-	-	-	-	-	-
MKDNEODP_02171	2.42e-166	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MKDNEODP_02172	4.56e-166	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
MKDNEODP_02173	2.17e-43	-	-	-	S	-	-	-	Putative regulatory protein
MKDNEODP_02174	5.03e-121	-	-	-	NO	-	-	-	SAF
MKDNEODP_02175	2.09e-41	-	-	-	-	-	-	-	-
MKDNEODP_02176	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
MKDNEODP_02177	6.37e-249	-	-	-	T	-	-	-	Forkhead associated domain
MKDNEODP_02178	6.07e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MKDNEODP_02179	2.41e-113	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MKDNEODP_02180	1.65e-180	-	-	-	S	-	-	-	alpha beta
MKDNEODP_02181	5.25e-313	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
MKDNEODP_02182	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MKDNEODP_02183	1.44e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MKDNEODP_02184	6.6e-241	-	-	-	V	-	-	-	ABC transporter
MKDNEODP_02185	3.58e-198	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
MKDNEODP_02187	8.53e-117	-	-	-	S	-	-	-	Helix-turn-helix
MKDNEODP_02188	7.62e-138	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
MKDNEODP_02189	2.54e-209	-	-	-	G	-	-	-	Phosphoglycerate mutase family
MKDNEODP_02190	2.31e-296	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
MKDNEODP_02192	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
MKDNEODP_02193	5.27e-37	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_02194	3.36e-42	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKDNEODP_02195	0.0	nplT	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
MKDNEODP_02196	3.63e-69	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
MKDNEODP_02197	5.51e-147	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
MKDNEODP_02198	8.95e-142	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
MKDNEODP_02199	9.07e-283	-	-	-	T	-	-	-	Histidine kinase
MKDNEODP_02200	2.12e-14	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
MKDNEODP_02201	2.07e-236	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKDNEODP_02202	2.74e-284	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MKDNEODP_02203	4.33e-315	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MKDNEODP_02204	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
MKDNEODP_02205	1.65e-133	-	-	-	S	-	-	-	PIN domain
MKDNEODP_02206	2.69e-116	-	-	-	K	-	-	-	Helix-turn-helix domain
MKDNEODP_02208	4.71e-31	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MKDNEODP_02209	1.08e-29	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MKDNEODP_02210	2.47e-134	-	-	-	-	-	-	-	-
MKDNEODP_02211	1.67e-259	-	-	-	-	-	-	-	-
MKDNEODP_02212	2.51e-143	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
MKDNEODP_02213	8.75e-138	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
MKDNEODP_02214	1.37e-95	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKDNEODP_02215	2.06e-208	-	-	-	M	-	-	-	pfam nlp p60
MKDNEODP_02216	1.25e-203	-	-	-	I	-	-	-	Serine aminopeptidase, S33
MKDNEODP_02217	4.22e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
MKDNEODP_02218	5.21e-41	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MKDNEODP_02219	4.08e-305	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
MKDNEODP_02220	6.02e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MKDNEODP_02221	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MKDNEODP_02222	2.11e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
MKDNEODP_02223	3.5e-272	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MKDNEODP_02224	9.92e-193	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MKDNEODP_02225	1.29e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MKDNEODP_02226	1.92e-196	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
MKDNEODP_02227	1.43e-115	-	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	cytidine deaminase activity
MKDNEODP_02228	7.72e-70	-	-	-	S	-	-	-	SdpI/YhfL protein family
MKDNEODP_02229	5.99e-143	-	-	-	E	-	-	-	Transglutaminase-like superfamily
MKDNEODP_02230	6.1e-85	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MKDNEODP_02231	2.55e-65	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MKDNEODP_02232	2.43e-166	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
MKDNEODP_02233	8.24e-83	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
MKDNEODP_02234	2.29e-48	-	-	-	-	-	-	-	-
MKDNEODP_02235	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MKDNEODP_02236	6.41e-103	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MKDNEODP_02237	7.79e-263	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MKDNEODP_02238	2.5e-100	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
MKDNEODP_02239	7.77e-280	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MKDNEODP_02240	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MKDNEODP_02241	2.09e-104	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
MKDNEODP_02242	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MKDNEODP_02243	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
MKDNEODP_02244	5.91e-299	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
MKDNEODP_02245	3.98e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MKDNEODP_02246	6.21e-303	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MKDNEODP_02247	1.18e-132	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MKDNEODP_02248	1e-144	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MKDNEODP_02249	1.79e-306	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MKDNEODP_02250	3.08e-209	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
MKDNEODP_02252	1.28e-183	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MKDNEODP_02253	9.63e-77	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MKDNEODP_02254	2.38e-272	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
MKDNEODP_02255	1.44e-132	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MKDNEODP_02256	0.0	corC	-	-	S	-	-	-	CBS domain
MKDNEODP_02257	1.61e-233	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MKDNEODP_02258	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
MKDNEODP_02259	5.23e-258	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
MKDNEODP_02260	5.05e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
MKDNEODP_02261	1.43e-308	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MKDNEODP_02262	1.08e-247	-	-	-	S	ko:K06889	-	ko00000	alpha beta
MKDNEODP_02263	1.54e-112	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MKDNEODP_02264	2.61e-286	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
MKDNEODP_02266	2.02e-32	-	-	-	S	-	-	-	Putative phage holin Dp-1
MKDNEODP_02267	1.43e-74	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MKDNEODP_02268	1.1e-26	-	-	-	-	-	-	-	-
MKDNEODP_02274	4.39e-205	-	-	-	S	-	-	-	cellulase activity
MKDNEODP_02276	1.16e-180	-	-	-	DNT	-	-	-	domain protein
MKDNEODP_02279	1.49e-90	-	-	-	-	-	-	-	-
MKDNEODP_02282	1.93e-84	-	-	-	-	-	-	-	-
MKDNEODP_02283	2.76e-52	-	-	-	-	-	-	-	-
MKDNEODP_02284	1.54e-150	-	-	-	S	-	-	-	Phage major capsid protein E
MKDNEODP_02285	4.44e-69	-	-	-	-	-	-	-	-
MKDNEODP_02286	1.04e-07	-	-	-	-	-	-	-	-
MKDNEODP_02287	4.69e-114	-	-	-	-	-	-	-	-
MKDNEODP_02288	1.34e-265	-	-	-	-	-	-	-	-
MKDNEODP_02289	0.0	-	-	-	S	-	-	-	Terminase