ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MFLEKNFE_00002 1.08e-208 - - - - - - - -
MFLEKNFE_00003 2.76e-28 - - - S - - - Cell surface protein
MFLEKNFE_00006 2.03e-12 - - - L - - - Helix-turn-helix domain
MFLEKNFE_00007 4.32e-16 - - - L - - - Helix-turn-helix domain
MFLEKNFE_00008 2.28e-22 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFLEKNFE_00009 2.15e-17 - - - M - - - Domain of unknown function (DUF5011)
MFLEKNFE_00011 3.07e-06 - - - D - - - Mycoplasma protein of unknown function, DUF285
MFLEKNFE_00013 2.72e-70 - - - K - - - helix_turn_helix, arabinose operon control protein
MFLEKNFE_00015 2.12e-27 - - - L ko:K07487 - ko00000 Transposase
MFLEKNFE_00016 9.07e-22 - - - L ko:K07487 - ko00000 Transposase
MFLEKNFE_00017 4.62e-22 - - - M - - - Domain of unknown function (DUF5011)
MFLEKNFE_00018 9.95e-122 - - - M - - - Glycosyl hydrolases family 25
MFLEKNFE_00019 3.95e-92 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
MFLEKNFE_00020 0.0 bgl 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MFLEKNFE_00021 4.02e-205 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MFLEKNFE_00022 0.0 - 2.3.1.204, 3.2.1.170, 3.2.1.24 GH38 G ko:K01191,ko:K15524,ko:K16869 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Glycosyl hydrolases family 38 N-terminal domain
MFLEKNFE_00023 0.0 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
MFLEKNFE_00024 2.66e-248 - - - K - - - Transcriptional regulator
MFLEKNFE_00025 0.0 ypdD - - G - - - Glycosyl hydrolase family 92
MFLEKNFE_00026 1.81e-274 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MFLEKNFE_00027 3.76e-212 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MFLEKNFE_00028 0.0 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
MFLEKNFE_00029 0.0 - 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFLEKNFE_00030 1.71e-139 ypcB - - S - - - integral membrane protein
MFLEKNFE_00031 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
MFLEKNFE_00032 0.0 ypcG - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Domain of unknown function (DUF3502)
MFLEKNFE_00033 6.47e-213 lplC - - U ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFLEKNFE_00034 1.29e-231 ypdA - - U ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFLEKNFE_00035 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
MFLEKNFE_00036 2.72e-199 - - - K - - - helix_turn_helix, arabinose operon control protein
MFLEKNFE_00037 0.0 mdlA2 - - V ko:K06147 - ko00000,ko02000 ABC transporter
MFLEKNFE_00038 0.0 yknV - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFLEKNFE_00039 1.48e-247 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
MFLEKNFE_00040 1.91e-201 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
MFLEKNFE_00041 6.96e-83 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MFLEKNFE_00042 2.5e-234 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
MFLEKNFE_00043 1.23e-129 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
MFLEKNFE_00044 3.33e-113 srlM1 - - K - - - Glucitol operon activator protein (GutM)
MFLEKNFE_00045 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MFLEKNFE_00046 2.21e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
MFLEKNFE_00047 2.53e-209 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
MFLEKNFE_00048 4.99e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MFLEKNFE_00049 7.82e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MFLEKNFE_00050 4.04e-241 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MFLEKNFE_00051 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MFLEKNFE_00052 2.51e-103 - - - T - - - Universal stress protein family
MFLEKNFE_00053 7.43e-130 padR - - K - - - Virulence activator alpha C-term
MFLEKNFE_00054 2.71e-135 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
MFLEKNFE_00055 1.44e-185 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
MFLEKNFE_00056 3.66e-113 - - - K - - - Acetyltransferase (GNAT) domain
MFLEKNFE_00057 3.3e-202 degV1 - - S - - - DegV family
MFLEKNFE_00058 1.67e-79 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
MFLEKNFE_00059 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MFLEKNFE_00061 2.76e-141 sip3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MFLEKNFE_00062 0.0 - - - - - - - -
MFLEKNFE_00064 2.23e-211 - - - S - - - Bacterial protein of unknown function (DUF916)
MFLEKNFE_00065 1.31e-143 - - - S - - - Cell surface protein
MFLEKNFE_00066 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MFLEKNFE_00067 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MFLEKNFE_00068 2.37e-173 jag - - S ko:K06346 - ko00000 R3H domain protein
MFLEKNFE_00069 2.26e-306 - - - Q - - - Imidazolonepropionase and related amidohydrolases
MFLEKNFE_00070 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFLEKNFE_00071 1.97e-13 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFLEKNFE_00072 1.55e-158 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MFLEKNFE_00073 3.74e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MFLEKNFE_00074 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MFLEKNFE_00075 8.19e-267 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MFLEKNFE_00076 3.82e-51 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
MFLEKNFE_00077 7.24e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MFLEKNFE_00078 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MFLEKNFE_00079 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MFLEKNFE_00080 5.95e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MFLEKNFE_00081 1.68e-108 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MFLEKNFE_00082 2.69e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MFLEKNFE_00083 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MFLEKNFE_00084 3.44e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MFLEKNFE_00085 8.77e-317 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MFLEKNFE_00086 4.96e-289 yttB - - EGP - - - Major Facilitator
MFLEKNFE_00087 9e-184 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MFLEKNFE_00088 3.25e-292 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MFLEKNFE_00090 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFLEKNFE_00092 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MFLEKNFE_00093 6.65e-282 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MFLEKNFE_00094 3.49e-269 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
MFLEKNFE_00095 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
MFLEKNFE_00096 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MFLEKNFE_00097 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MFLEKNFE_00099 6.89e-183 - - - S - - - haloacid dehalogenase-like hydrolase
MFLEKNFE_00100 1.1e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MFLEKNFE_00101 0.0 trePP 2.4.1.216, 2.4.1.8 GH65 G ko:K00691,ko:K03731 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
MFLEKNFE_00102 3.21e-104 - - - S - - - Pyridoxamine 5'-phosphate oxidase
MFLEKNFE_00103 4.37e-43 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock protein domain
MFLEKNFE_00104 1.47e-49 - - - - - - - -
MFLEKNFE_00106 2.22e-169 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MFLEKNFE_00107 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFLEKNFE_00108 5.04e-313 yycH - - S - - - YycH protein
MFLEKNFE_00109 3.54e-195 yycI - - S - - - YycH protein
MFLEKNFE_00110 1.71e-200 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MFLEKNFE_00111 1.5e-253 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MFLEKNFE_00112 6.08e-107 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MFLEKNFE_00113 2e-123 - - - K - - - Bacterial regulatory proteins, tetR family
MFLEKNFE_00114 0.0 - - - C - - - Belongs to the aldehyde dehydrogenase family
MFLEKNFE_00115 5.97e-157 ung2 - - L - - - Uracil-DNA glycosylase
MFLEKNFE_00116 2.24e-155 pnb - - C - - - nitroreductase
MFLEKNFE_00117 2.02e-85 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
MFLEKNFE_00118 2.14e-148 - - - S - - - Elongation factor G-binding protein, N-terminal
MFLEKNFE_00119 0.0 - - - C - - - FMN_bind
MFLEKNFE_00120 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MFLEKNFE_00121 3.43e-203 - - - K - - - LysR family
MFLEKNFE_00122 1.69e-93 - - - C - - - FMN binding
MFLEKNFE_00123 1.82e-97 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MFLEKNFE_00124 3.34e-210 - - - S - - - KR domain
MFLEKNFE_00125 2.73e-202 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
MFLEKNFE_00126 5.07e-157 ydgI - - C - - - Nitroreductase family
MFLEKNFE_00127 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
MFLEKNFE_00128 2.22e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MFLEKNFE_00129 2.28e-250 pva1 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MFLEKNFE_00130 0.0 - - - S - - - Putative threonine/serine exporter
MFLEKNFE_00131 6.86e-175 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MFLEKNFE_00132 0.0 hpaH 1.14.14.8, 1.14.14.9 - Q ko:K00483,ko:K16901 ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220 ko00000,ko00001,ko01000 4-hydroxyphenylacetate
MFLEKNFE_00133 1.65e-106 - - - S - - - ASCH
MFLEKNFE_00134 1.25e-164 - - - F - - - glutamine amidotransferase
MFLEKNFE_00135 1.88e-216 - - - K - - - WYL domain
MFLEKNFE_00136 6.65e-152 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MFLEKNFE_00137 0.0 fusA1 - - J - - - elongation factor G
MFLEKNFE_00138 3.66e-59 - - - S - - - Protein of unknown function
MFLEKNFE_00139 2.84e-81 - - - S - - - Protein of unknown function
MFLEKNFE_00140 4.28e-195 - - - EG - - - EamA-like transporter family
MFLEKNFE_00141 7.65e-121 yfbM - - K - - - FR47-like protein
MFLEKNFE_00142 1.4e-162 - - - S - - - DJ-1/PfpI family
MFLEKNFE_00143 3.42e-234 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
MFLEKNFE_00144 1.92e-67 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MFLEKNFE_00145 6.97e-301 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
MFLEKNFE_00146 3.5e-217 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MFLEKNFE_00147 7.76e-181 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MFLEKNFE_00148 2.38e-99 - - - - - - - -
MFLEKNFE_00149 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MFLEKNFE_00150 5.9e-181 - - - - - - - -
MFLEKNFE_00151 4.07e-05 - - - - - - - -
MFLEKNFE_00152 8.05e-186 ant1 2.7.7.47 - H ko:K00984 - ko00000,ko01000,ko01504 Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
MFLEKNFE_00153 1.67e-54 - - - - - - - -
MFLEKNFE_00154 7.41e-167 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFLEKNFE_00155 8.38e-193 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MFLEKNFE_00156 1.84e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
MFLEKNFE_00157 1.39e-156 rcfB - - K - - - Crp-like helix-turn-helix domain
MFLEKNFE_00158 7.9e-306 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
MFLEKNFE_00159 2.65e-162 larB - - S ko:K06898 - ko00000 AIR carboxylase
MFLEKNFE_00160 2.03e-179 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MFLEKNFE_00161 6.32e-99 larC2 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Protein of unknown function DUF111
MFLEKNFE_00162 1.19e-170 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MFLEKNFE_00163 6.38e-194 larE - - S ko:K06864 - ko00000 NAD synthase
MFLEKNFE_00164 4.79e-225 - - - C - - - Zinc-binding dehydrogenase
MFLEKNFE_00165 2.27e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MFLEKNFE_00166 9.72e-188 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MFLEKNFE_00167 2.68e-143 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MFLEKNFE_00168 9.14e-265 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
MFLEKNFE_00169 7.45e-178 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MFLEKNFE_00170 0.0 - - - L - - - HIRAN domain
MFLEKNFE_00171 1.24e-109 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MFLEKNFE_00172 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
MFLEKNFE_00173 8.96e-160 - - - - - - - -
MFLEKNFE_00174 5.08e-192 - - - I - - - Alpha/beta hydrolase family
MFLEKNFE_00175 0.0 pacL1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MFLEKNFE_00176 5.24e-181 - - - F - - - Phosphorylase superfamily
MFLEKNFE_00177 2.92e-38 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MFLEKNFE_00178 5.13e-144 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MFLEKNFE_00179 1.27e-98 - - - K - - - Transcriptional regulator
MFLEKNFE_00180 2.31e-95 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MFLEKNFE_00181 1.35e-106 - - - S - - - Protein of unknown function (DUF3021)
MFLEKNFE_00182 4.14e-97 - - - K - - - LytTr DNA-binding domain
MFLEKNFE_00183 5.38e-290 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MFLEKNFE_00184 3.98e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MFLEKNFE_00185 2.79e-274 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
MFLEKNFE_00187 2.16e-204 morA - - S - - - reductase
MFLEKNFE_00188 8.21e-213 - 1.1.1.65 - C ko:K05275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko01000 Aldo keto reductase
MFLEKNFE_00189 7.84e-106 - - - F - - - Nucleoside 2-deoxyribosyltransferase like
MFLEKNFE_00190 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MFLEKNFE_00191 4.03e-132 - - - - - - - -
MFLEKNFE_00192 0.0 - - - - - - - -
MFLEKNFE_00193 1.86e-267 - - - C - - - Oxidoreductase
MFLEKNFE_00194 3.28e-193 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MFLEKNFE_00195 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_00196 2.57e-128 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
MFLEKNFE_00197 4.37e-167 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MFLEKNFE_00198 4.14e-72 - - - K - - - Transcriptional regulator PadR-like family
MFLEKNFE_00199 1.56e-182 - - - - - - - -
MFLEKNFE_00200 3.16e-191 - - - - - - - -
MFLEKNFE_00201 3.37e-115 - - - - - - - -
MFLEKNFE_00202 1.01e-184 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
MFLEKNFE_00203 1.04e-218 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MFLEKNFE_00204 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
MFLEKNFE_00205 9.77e-152 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
MFLEKNFE_00206 0.0 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
MFLEKNFE_00207 2.04e-99 - - - T - - - ECF transporter, substrate-specific component
MFLEKNFE_00209 1.85e-121 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
MFLEKNFE_00210 2.35e-243 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
MFLEKNFE_00211 9.52e-240 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
MFLEKNFE_00212 2.75e-131 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
MFLEKNFE_00213 6.76e-75 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
MFLEKNFE_00214 4e-172 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MFLEKNFE_00215 2.65e-245 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
MFLEKNFE_00216 1.83e-231 yvdE - - K - - - helix_turn _helix lactose operon repressor
MFLEKNFE_00217 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
MFLEKNFE_00218 4.69e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MFLEKNFE_00219 2.16e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFLEKNFE_00220 2.83e-206 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFLEKNFE_00221 1.75e-191 malA - - S - - - maltodextrose utilization protein MalA
MFLEKNFE_00222 0.0 malS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Glycogen debranching enzyme, glucanotransferase domain
MFLEKNFE_00223 2.44e-267 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MFLEKNFE_00224 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MFLEKNFE_00225 0.0 - 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 85
MFLEKNFE_00226 8.23e-61 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
MFLEKNFE_00227 1.54e-216 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MFLEKNFE_00228 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFLEKNFE_00229 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MFLEKNFE_00230 2.4e-230 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
MFLEKNFE_00231 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MFLEKNFE_00232 9.92e-212 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
MFLEKNFE_00233 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MFLEKNFE_00234 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MFLEKNFE_00235 5.99e-213 mleR - - K - - - LysR substrate binding domain
MFLEKNFE_00236 0.0 - - - M - - - domain protein
MFLEKNFE_00238 1.03e-201 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MFLEKNFE_00239 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFLEKNFE_00240 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFLEKNFE_00241 1.31e-102 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MFLEKNFE_00242 1.19e-277 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFLEKNFE_00243 1.24e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MFLEKNFE_00244 2.73e-147 pgm1 - - G - - - phosphoglycerate mutase
MFLEKNFE_00245 1.01e-228 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
MFLEKNFE_00246 6.33e-46 - - - - - - - -
MFLEKNFE_00247 4.69e-79 - - - S - - - Domain of unknown function (DU1801)
MFLEKNFE_00248 6.21e-208 fbpA - - K - - - Domain of unknown function (DUF814)
MFLEKNFE_00249 2.6e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MFLEKNFE_00250 3.81e-18 - - - - - - - -
MFLEKNFE_00251 3.18e-77 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MFLEKNFE_00252 5.66e-74 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MFLEKNFE_00253 0.0 - - - S ko:K18231,ko:K19349 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ATPases associated with a variety of cellular activities
MFLEKNFE_00254 6.11e-150 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MFLEKNFE_00255 0.0 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MFLEKNFE_00256 1.43e-131 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC transporter permease
MFLEKNFE_00257 6.07e-117 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
MFLEKNFE_00258 5.3e-202 dkgB - - S - - - reductase
MFLEKNFE_00259 1.28e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MFLEKNFE_00260 1.2e-91 - - - - - - - -
MFLEKNFE_00261 3.16e-170 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MFLEKNFE_00263 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MFLEKNFE_00264 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MFLEKNFE_00265 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
MFLEKNFE_00266 5.33e-103 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFLEKNFE_00267 7.49e-282 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
MFLEKNFE_00268 1.21e-111 - - - - - - - -
MFLEKNFE_00269 1.96e-75 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MFLEKNFE_00270 7.19e-68 - - - - - - - -
MFLEKNFE_00271 1.22e-125 - - - - - - - -
MFLEKNFE_00272 1.56e-162 - - - L ko:K07487 - ko00000 Transposase
MFLEKNFE_00273 0.0 - - - S - - - membrane
MFLEKNFE_00274 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MFLEKNFE_00275 5.33e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MFLEKNFE_00276 9.29e-132 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MFLEKNFE_00277 3.52e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
MFLEKNFE_00278 6.33e-46 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MFLEKNFE_00279 2.6e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MFLEKNFE_00280 4.65e-141 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
MFLEKNFE_00281 6.68e-89 yqhL - - P - - - Rhodanese-like protein
MFLEKNFE_00282 1.44e-31 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
MFLEKNFE_00283 1.83e-177 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
MFLEKNFE_00284 1.33e-224 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MFLEKNFE_00285 7.79e-85 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
MFLEKNFE_00286 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MFLEKNFE_00287 1.77e-205 - - - - - - - -
MFLEKNFE_00288 1.34e-232 - - - - - - - -
MFLEKNFE_00289 3.55e-127 - - - S - - - Protein conserved in bacteria
MFLEKNFE_00290 1.87e-74 - - - - - - - -
MFLEKNFE_00291 2.97e-41 - - - - - - - -
MFLEKNFE_00294 9.81e-27 - - - - - - - -
MFLEKNFE_00295 8.15e-125 - - - K - - - Transcriptional regulator
MFLEKNFE_00296 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MFLEKNFE_00297 7.97e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
MFLEKNFE_00298 2.33e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MFLEKNFE_00299 6.04e-249 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MFLEKNFE_00300 1.43e-129 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MFLEKNFE_00301 1.7e-96 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MFLEKNFE_00302 9.43e-90 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MFLEKNFE_00303 4.82e-194 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MFLEKNFE_00304 3.99e-313 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MFLEKNFE_00305 7.55e-44 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MFLEKNFE_00306 5.49e-205 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MFLEKNFE_00307 4.49e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MFLEKNFE_00308 5.28e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MFLEKNFE_00309 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MFLEKNFE_00310 4.51e-284 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_00311 7.11e-135 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFLEKNFE_00312 3.8e-224 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MFLEKNFE_00313 1.36e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFLEKNFE_00314 2.38e-72 - - - - - - - -
MFLEKNFE_00315 6.96e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MFLEKNFE_00316 3.93e-41 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MFLEKNFE_00317 5.04e-278 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MFLEKNFE_00318 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MFLEKNFE_00319 1.49e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MFLEKNFE_00320 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MFLEKNFE_00321 1.62e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MFLEKNFE_00322 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MFLEKNFE_00323 9.9e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MFLEKNFE_00324 2.22e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MFLEKNFE_00325 2.61e-160 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MFLEKNFE_00326 1.61e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MFLEKNFE_00327 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
MFLEKNFE_00328 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MFLEKNFE_00329 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MFLEKNFE_00330 1.79e-243 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MFLEKNFE_00331 3.33e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFLEKNFE_00332 4.49e-167 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MFLEKNFE_00333 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MFLEKNFE_00334 7.71e-298 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MFLEKNFE_00335 1.46e-77 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MFLEKNFE_00336 7.69e-300 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MFLEKNFE_00337 1.6e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MFLEKNFE_00338 9.99e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MFLEKNFE_00339 2.24e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MFLEKNFE_00340 1.57e-179 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MFLEKNFE_00341 3.15e-78 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MFLEKNFE_00342 1.03e-66 - - - - - - - -
MFLEKNFE_00343 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MFLEKNFE_00344 1.1e-112 - - - - - - - -
MFLEKNFE_00345 2.05e-179 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MFLEKNFE_00346 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
MFLEKNFE_00348 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
MFLEKNFE_00349 8.08e-135 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
MFLEKNFE_00350 1.42e-224 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MFLEKNFE_00351 6.06e-159 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
MFLEKNFE_00352 1.51e-140 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
MFLEKNFE_00353 1.79e-287 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MFLEKNFE_00354 4.82e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MFLEKNFE_00355 1.45e-126 entB - - Q - - - Isochorismatase family
MFLEKNFE_00356 3.53e-227 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 Zinc-binding dehydrogenase
MFLEKNFE_00357 1.95e-88 ybbJ - - K - - - Acetyltransferase (GNAT) family
MFLEKNFE_00358 1.62e-276 - - - E - - - glutamate:sodium symporter activity
MFLEKNFE_00359 1.38e-273 hipO1 - - E ko:K21613 - ko00000,ko01000,ko01002 Peptidase family M20/M25/M40
MFLEKNFE_00360 1.56e-251 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MFLEKNFE_00361 2.12e-77 - - - S - - - Protein of unknown function (DUF1648)
MFLEKNFE_00362 6.84e-186 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLEKNFE_00363 8.02e-230 yneE - - K - - - Transcriptional regulator
MFLEKNFE_00364 8.55e-99 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MFLEKNFE_00365 1.97e-230 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFLEKNFE_00366 6.16e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFLEKNFE_00367 4.22e-216 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
MFLEKNFE_00368 1.26e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MFLEKNFE_00369 5.38e-290 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MFLEKNFE_00370 5.25e-96 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MFLEKNFE_00371 7.23e-93 fabZ2 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
MFLEKNFE_00372 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
MFLEKNFE_00373 2.62e-202 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MFLEKNFE_00374 1.96e-178 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
MFLEKNFE_00375 5.4e-174 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MFLEKNFE_00376 1.01e-128 - - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
MFLEKNFE_00377 3.64e-162 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MFLEKNFE_00378 1.07e-206 - - - K - - - LysR substrate binding domain
MFLEKNFE_00379 4.94e-114 ykhA - - I - - - Thioesterase superfamily
MFLEKNFE_00380 2.66e-247 rsgA_2 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MFLEKNFE_00381 2.46e-120 - - - K - - - transcriptional regulator
MFLEKNFE_00382 0.0 - - - EGP - - - Major Facilitator
MFLEKNFE_00383 6.56e-193 - - - O - - - Band 7 protein
MFLEKNFE_00384 1.85e-101 - - - L - - - Pfam:Integrase_AP2
MFLEKNFE_00388 1.01e-31 - - - - - - - -
MFLEKNFE_00391 2.06e-51 - - - S - - - protein disulfide oxidoreductase activity
MFLEKNFE_00394 1.23e-25 - - - K - - - Cro/C1-type HTH DNA-binding domain
MFLEKNFE_00395 2.1e-16 - - - K - - - Cro/C1-type HTH DNA-binding domain
MFLEKNFE_00396 1.65e-07 - - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
MFLEKNFE_00404 4.68e-46 - - - - - - - -
MFLEKNFE_00405 1.12e-121 - - - S - - - AAA domain
MFLEKNFE_00406 6.02e-69 - - - S - - - Protein of unknown function (DUF669)
MFLEKNFE_00407 2.75e-41 - - - L - - - DnaD domain protein
MFLEKNFE_00408 4.18e-201 - - - S - - - IstB-like ATP binding protein
MFLEKNFE_00410 1.49e-50 - - - - - - - -
MFLEKNFE_00411 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
MFLEKNFE_00412 1.03e-74 - - - S - - - Transcriptional regulator, RinA family
MFLEKNFE_00413 8.7e-179 - - - - - - - -
MFLEKNFE_00414 1.29e-86 - - - K - - - IrrE N-terminal-like domain
MFLEKNFE_00415 5.47e-21 - - - - - - - -
MFLEKNFE_00416 9.87e-70 - - - S - - - Domain of unknown function (DUF4868)
MFLEKNFE_00417 4.05e-12 - - - - - - - -
MFLEKNFE_00418 3.55e-42 - - - S - - - Helix-turn-helix of insertion element transposase
MFLEKNFE_00419 0.0 - - - S ko:K06909 - ko00000 Phage terminase, large subunit
MFLEKNFE_00420 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
MFLEKNFE_00421 1.11e-213 - - - S - - - Phage Mu protein F like protein
MFLEKNFE_00422 2.54e-108 - - - S - - - Domain of unknown function (DUF4355)
MFLEKNFE_00423 1.1e-257 gpG - - - - - - -
MFLEKNFE_00424 5.17e-83 - - - S - - - Phage gp6-like head-tail connector protein
MFLEKNFE_00425 4e-69 - - - - - - - -
MFLEKNFE_00426 1.48e-117 - - - - - - - -
MFLEKNFE_00427 4.48e-85 - - - - - - - -
MFLEKNFE_00428 1.47e-136 - - - - - - - -
MFLEKNFE_00429 1.41e-115 - - - S - - - Phage tail assembly chaperone protein, TAC
MFLEKNFE_00431 0.0 - - - D - - - domain protein
MFLEKNFE_00432 1.98e-181 - - - S - - - phage tail
MFLEKNFE_00433 0.0 - - - M - - - Prophage endopeptidase tail
MFLEKNFE_00434 3.46e-241 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MFLEKNFE_00435 1.11e-140 - - - S - - - Domain of unknown function (DUF2479)
MFLEKNFE_00438 2.56e-34 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
MFLEKNFE_00439 3.36e-178 - - - M - - - hydrolase, family 25
MFLEKNFE_00440 4.01e-35 - - - S - - - Haemolysin XhlA
MFLEKNFE_00441 1.05e-22 - - - S - - - Bacteriophage holin
MFLEKNFE_00442 2.74e-05 - - - - - - - -
MFLEKNFE_00444 1.22e-125 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
MFLEKNFE_00445 1.08e-71 - - - V - - - HNH endonuclease
MFLEKNFE_00447 8.14e-47 - - - L - - - Pfam:Integrase_AP2
MFLEKNFE_00451 1.19e-13 - - - - - - - -
MFLEKNFE_00453 1.43e-69 - - - - - - - -
MFLEKNFE_00454 1.42e-39 - - - - - - - -
MFLEKNFE_00455 1.69e-276 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MFLEKNFE_00456 9.96e-147 - 1.14.99.53 AA10 S ko:K21713 - ko00000,ko01000 Lytic polysaccharide mono-oxygenase, cellulose-degrading
MFLEKNFE_00457 3.16e-64 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
MFLEKNFE_00458 2.05e-55 - - - - - - - -
MFLEKNFE_00459 4.98e-107 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
MFLEKNFE_00460 3.05e-99 - - - T - - - Belongs to the universal stress protein A family
MFLEKNFE_00461 3.92e-87 - - - S - - - Protein of unknown function (DUF805)
MFLEKNFE_00462 1.79e-211 - - - I - - - Diacylglycerol kinase catalytic domain
MFLEKNFE_00463 1.51e-48 - - - - - - - -
MFLEKNFE_00464 5.79e-21 - - - - - - - -
MFLEKNFE_00465 2.22e-55 - - - S - - - transglycosylase associated protein
MFLEKNFE_00466 4e-40 - - - S - - - CsbD-like
MFLEKNFE_00467 1.06e-53 - - - - - - - -
MFLEKNFE_00468 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MFLEKNFE_00469 4.87e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MFLEKNFE_00470 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MFLEKNFE_00471 1.04e-218 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
MFLEKNFE_00472 5.03e-182 - - - U ko:K10716 - ko00000,ko02000 Ion channel
MFLEKNFE_00473 1.52e-67 - - - - - - - -
MFLEKNFE_00474 2.12e-57 - - - - - - - -
MFLEKNFE_00475 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MFLEKNFE_00476 0.0 - - - E ko:K03294 - ko00000 Amino Acid
MFLEKNFE_00477 3.86e-192 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MFLEKNFE_00478 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
MFLEKNFE_00479 2.06e-158 - - - S - - - Domain of unknown function (DUF4767)
MFLEKNFE_00480 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MFLEKNFE_00481 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MFLEKNFE_00482 9.23e-245 galM2 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MFLEKNFE_00483 1.01e-249 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MFLEKNFE_00484 1.77e-262 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MFLEKNFE_00485 1.1e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MFLEKNFE_00486 1.48e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
MFLEKNFE_00487 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MFLEKNFE_00488 2.53e-107 ypmB - - S - - - protein conserved in bacteria
MFLEKNFE_00489 3.1e-289 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MFLEKNFE_00490 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MFLEKNFE_00491 1.13e-165 dnaD - - L ko:K02086 - ko00000 Replication initiation and membrane attachment
MFLEKNFE_00493 2.32e-238 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MFLEKNFE_00494 4.94e-142 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFLEKNFE_00495 1.3e-202 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MFLEKNFE_00496 5.32e-109 - - - T - - - Universal stress protein family
MFLEKNFE_00497 0.0 ftpA - - P ko:K02011 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFLEKNFE_00498 3.28e-233 ftpB - - P ko:K02012 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MFLEKNFE_00499 2.8e-229 phnT 3.6.3.30 - P ko:K02010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MFLEKNFE_00500 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MFLEKNFE_00501 3.6e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MFLEKNFE_00502 2.12e-142 ypsA - - S - - - Belongs to the UPF0398 family
MFLEKNFE_00503 9.98e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MFLEKNFE_00505 4.11e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MFLEKNFE_00507 1.7e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MFLEKNFE_00508 2.26e-95 - - - S - - - SnoaL-like domain
MFLEKNFE_00509 3.2e-254 - - - M - - - Glycosyltransferase, group 2 family protein
MFLEKNFE_00510 2.85e-266 mccF - - V - - - LD-carboxypeptidase
MFLEKNFE_00511 1.66e-101 - - - K - - - Acetyltransferase (GNAT) domain
MFLEKNFE_00512 2.13e-312 - - - M ko:K07273 - ko00000 hydrolase, family 25
MFLEKNFE_00513 1.44e-234 - - - V - - - LD-carboxypeptidase
MFLEKNFE_00514 1.99e-159 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
MFLEKNFE_00515 3.99e-158 - - - P ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MFLEKNFE_00516 1.37e-248 - - - - - - - -
MFLEKNFE_00517 1.5e-186 - - - S - - - hydrolase activity, acting on ester bonds
MFLEKNFE_00518 1.47e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
MFLEKNFE_00519 3.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
MFLEKNFE_00520 5.04e-82 esbA - - S - - - Family of unknown function (DUF5322)
MFLEKNFE_00521 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MFLEKNFE_00522 1.65e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MFLEKNFE_00523 9.72e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MFLEKNFE_00524 1.9e-115 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MFLEKNFE_00525 4.89e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
MFLEKNFE_00526 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MFLEKNFE_00527 0.0 - - - S - - - Bacterial membrane protein, YfhO
MFLEKNFE_00528 2.01e-145 - - - G - - - Phosphoglycerate mutase family
MFLEKNFE_00529 1.9e-93 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
MFLEKNFE_00531 1.92e-168 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
MFLEKNFE_00532 2.08e-92 - - - S - - - LuxR family transcriptional regulator
MFLEKNFE_00533 1.19e-176 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
MFLEKNFE_00534 1.87e-117 - - - F - - - NUDIX domain
MFLEKNFE_00535 5.08e-207 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_00536 9.28e-171 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MFLEKNFE_00537 0.0 FbpA - - K - - - Fibronectin-binding protein
MFLEKNFE_00538 1.97e-87 - - - K - - - Transcriptional regulator
MFLEKNFE_00539 1.11e-205 - - - S - - - EDD domain protein, DegV family
MFLEKNFE_00540 2.47e-101 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
MFLEKNFE_00541 2.9e-170 - - - S - - - Protein of unknown function (DUF975)
MFLEKNFE_00542 3.03e-40 - - - - - - - -
MFLEKNFE_00543 5.59e-64 - - - - - - - -
MFLEKNFE_00544 6.64e-189 - - - C - - - Domain of unknown function (DUF4931)
MFLEKNFE_00545 3.87e-264 pmrB - - EGP - - - Major Facilitator Superfamily
MFLEKNFE_00547 1.33e-67 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
MFLEKNFE_00548 2.98e-166 yejC - - S - - - Protein of unknown function (DUF1003)
MFLEKNFE_00549 2.59e-177 XK27_00890 - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
MFLEKNFE_00550 4.31e-312 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MFLEKNFE_00551 1.97e-110 - - - S - - - Pfam:DUF3816
MFLEKNFE_00552 1.21e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MFLEKNFE_00553 1.54e-144 - - - - - - - -
MFLEKNFE_00554 1.08e-243 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MFLEKNFE_00555 1.57e-184 - - - S - - - Peptidase_C39 like family
MFLEKNFE_00556 1.04e-120 - - - S - - - Protein of unknown function (DUF1694)
MFLEKNFE_00557 3.38e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MFLEKNFE_00558 9.38e-189 - - - KT - - - helix_turn_helix, mercury resistance
MFLEKNFE_00559 3.41e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MFLEKNFE_00560 1.86e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
MFLEKNFE_00561 1.63e-238 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MFLEKNFE_00562 7.14e-157 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_00563 1.12e-116 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
MFLEKNFE_00564 5.72e-238 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
MFLEKNFE_00565 5.04e-127 ywjB - - H - - - RibD C-terminal domain
MFLEKNFE_00566 1.14e-257 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MFLEKNFE_00567 2.56e-112 - - - S - - - Membrane
MFLEKNFE_00568 2.11e-199 mleP3 - - S ko:K07088 - ko00000 Membrane transport protein
MFLEKNFE_00569 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
MFLEKNFE_00570 7.15e-260 - - - EGP - - - Major Facilitator Superfamily
MFLEKNFE_00571 5.94e-162 - 3.8.1.2 - S ko:K01560 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MFLEKNFE_00572 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MFLEKNFE_00573 4.03e-104 - - - S - - - Domain of unknown function (DUF4811)
MFLEKNFE_00574 1.49e-131 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MFLEKNFE_00575 4.38e-222 - - - S - - - Conserved hypothetical protein 698
MFLEKNFE_00576 2.06e-194 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
MFLEKNFE_00577 0.0 tagE5 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
MFLEKNFE_00578 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MFLEKNFE_00580 2.72e-90 - - - M - - - LysM domain
MFLEKNFE_00581 3.92e-120 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
MFLEKNFE_00582 4.23e-215 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_00583 6.76e-270 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MFLEKNFE_00584 6.27e-166 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLEKNFE_00585 2e-73 cmd 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MFLEKNFE_00586 4.77e-100 yphH - - S - - - Cupin domain
MFLEKNFE_00587 1.27e-103 - - - K - - - transcriptional regulator, MerR family
MFLEKNFE_00588 5.3e-302 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MFLEKNFE_00589 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MFLEKNFE_00590 2.03e-155 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_00592 2.93e-151 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MFLEKNFE_00593 3.18e-141 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MFLEKNFE_00594 1.03e-150 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MFLEKNFE_00595 2.82e-110 - - - - - - - -
MFLEKNFE_00596 5.14e-111 yvbK - - K - - - GNAT family
MFLEKNFE_00597 3.98e-49 - - - - - - - -
MFLEKNFE_00598 2.81e-64 - - - - - - - -
MFLEKNFE_00599 5.46e-145 pgm8 - - G - - - Histidine phosphatase superfamily (branch 1)
MFLEKNFE_00600 2.65e-78 - - - S - - - Domain of unknown function (DUF4440)
MFLEKNFE_00601 1.57e-202 - - - K - - - LysR substrate binding domain
MFLEKNFE_00602 2.53e-134 - - - GM - - - NAD(P)H-binding
MFLEKNFE_00603 2.03e-248 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MFLEKNFE_00604 2.9e-194 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MFLEKNFE_00605 1.15e-179 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MFLEKNFE_00606 2.92e-106 - - - S - - - Protein of unknown function (DUF1211)
MFLEKNFE_00607 2.47e-97 - - - C - - - Flavodoxin
MFLEKNFE_00608 1.38e-160 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
MFLEKNFE_00609 1.07e-116 - - - U ko:K05340 - ko00000,ko02000 sugar transport
MFLEKNFE_00610 1.83e-111 - - - GM - - - NAD(P)H-binding
MFLEKNFE_00611 7.86e-138 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MFLEKNFE_00612 5.63e-98 - - - K - - - Transcriptional regulator
MFLEKNFE_00614 1.03e-31 - - - C - - - Flavodoxin
MFLEKNFE_00615 1.69e-08 adhR - - K - - - helix_turn_helix, mercury resistance
MFLEKNFE_00616 9.99e-147 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLEKNFE_00617 2.41e-165 - - - C - - - Aldo keto reductase
MFLEKNFE_00618 4.02e-181 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MFLEKNFE_00619 3.08e-178 - - - EGP ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
MFLEKNFE_00620 5.55e-106 - - - GM - - - NAD(P)H-binding
MFLEKNFE_00621 2.1e-99 - - - T - - - Belongs to the universal stress protein A family
MFLEKNFE_00622 1.04e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
MFLEKNFE_00623 2.4e-160 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MFLEKNFE_00624 1.12e-105 - - - - - - - -
MFLEKNFE_00625 3.73e-131 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MFLEKNFE_00626 3.45e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MFLEKNFE_00627 1.25e-130 - - - M - - - Protein of unknown function (DUF3737)
MFLEKNFE_00628 2.02e-246 - - - C - - - Aldo/keto reductase family
MFLEKNFE_00630 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFLEKNFE_00631 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFLEKNFE_00632 3.7e-313 - - - EGP - - - Major Facilitator
MFLEKNFE_00635 1.24e-229 yhgE - - V ko:K01421 - ko00000 domain protein
MFLEKNFE_00636 1.74e-123 - - - K - - - Transcriptional regulator (TetR family)
MFLEKNFE_00637 6.88e-71 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MFLEKNFE_00638 3.34e-199 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MFLEKNFE_00639 1.06e-138 yokL3 - - J - - - Acetyltransferase (GNAT) domain
MFLEKNFE_00640 3.05e-126 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MFLEKNFE_00641 1.92e-283 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MFLEKNFE_00642 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
MFLEKNFE_00643 4.68e-190 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MFLEKNFE_00644 0.0 - - - S - - - Predicted membrane protein (DUF2207)
MFLEKNFE_00645 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
MFLEKNFE_00646 2.33e-265 - - - EGP - - - Major facilitator Superfamily
MFLEKNFE_00647 6.28e-219 ropB - - K - - - Helix-turn-helix XRE-family like proteins
MFLEKNFE_00648 5.06e-298 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
MFLEKNFE_00649 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
MFLEKNFE_00650 6.45e-203 - - - I - - - alpha/beta hydrolase fold
MFLEKNFE_00651 3.39e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
MFLEKNFE_00652 0.0 - - - - - - - -
MFLEKNFE_00653 2e-52 - - - S - - - Cytochrome B5
MFLEKNFE_00654 5.02e-117 pts21A - - G ko:K02755 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MFLEKNFE_00655 2.05e-279 - - - T - - - Diguanylate cyclase, GGDEF domain
MFLEKNFE_00656 2.82e-163 - - - T - - - Putative diguanylate phosphodiesterase
MFLEKNFE_00657 3.83e-135 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MFLEKNFE_00658 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MFLEKNFE_00659 1.56e-108 - - - - - - - -
MFLEKNFE_00660 5.97e-96 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MFLEKNFE_00661 5.32e-242 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MFLEKNFE_00662 2.09e-244 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MFLEKNFE_00663 3.7e-30 - - - - - - - -
MFLEKNFE_00664 1.84e-134 - - - - - - - -
MFLEKNFE_00665 5.12e-212 - - - K - - - LysR substrate binding domain
MFLEKNFE_00666 1.24e-313 - - - P - - - Sodium:sulfate symporter transmembrane region
MFLEKNFE_00667 0.0 - 4.1.1.98 - H ko:K03182 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MFLEKNFE_00668 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MFLEKNFE_00669 3.22e-181 - - - S - - - zinc-ribbon domain
MFLEKNFE_00671 4.29e-50 - - - - - - - -
MFLEKNFE_00672 1.48e-171 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
MFLEKNFE_00673 4.07e-232 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MFLEKNFE_00674 0.0 - - - I - - - acetylesterase activity
MFLEKNFE_00675 1.99e-297 - - - M - - - Collagen binding domain
MFLEKNFE_00676 6.92e-206 yicL - - EG - - - EamA-like transporter family
MFLEKNFE_00677 3.03e-166 - - - E - - - lipolytic protein G-D-S-L family
MFLEKNFE_00678 1.44e-226 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
MFLEKNFE_00679 1.98e-142 - - - K - - - Transcriptional regulator C-terminal region
MFLEKNFE_00680 8.76e-63 - - - K - - - HxlR-like helix-turn-helix
MFLEKNFE_00681 8.78e-206 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MFLEKNFE_00682 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MFLEKNFE_00683 6.37e-125 - - - K - - - Transcriptional regulator, MarR family
MFLEKNFE_00684 3.29e-153 ydgI3 - - C - - - Nitroreductase family
MFLEKNFE_00685 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MFLEKNFE_00686 7.52e-139 - - - S ko:K05833 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MFLEKNFE_00687 4.78e-197 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MFLEKNFE_00688 7.28e-218 XK27_00670 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MFLEKNFE_00689 0.0 - - - - - - - -
MFLEKNFE_00690 1.4e-82 - - - - - - - -
MFLEKNFE_00691 6.17e-239 - - - S - - - Cell surface protein
MFLEKNFE_00692 1.27e-137 - - - S - - - WxL domain surface cell wall-binding
MFLEKNFE_00693 1.91e-124 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
MFLEKNFE_00694 1.61e-157 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFLEKNFE_00695 1.28e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
MFLEKNFE_00696 3.79e-192 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
MFLEKNFE_00697 2.29e-195 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
MFLEKNFE_00698 1.04e-269 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
MFLEKNFE_00700 1.15e-43 - - - - - - - -
MFLEKNFE_00701 6.9e-168 zmp3 - - O - - - Zinc-dependent metalloprotease
MFLEKNFE_00702 2.88e-106 gtcA3 - - S - - - GtrA-like protein
MFLEKNFE_00703 4.08e-158 - - - K - - - Helix-turn-helix XRE-family like proteins
MFLEKNFE_00704 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MFLEKNFE_00705 1.18e-94 usp2 - - T - - - Belongs to the universal stress protein A family
MFLEKNFE_00706 2.87e-61 - - - - - - - -
MFLEKNFE_00707 1.81e-150 - - - S - - - SNARE associated Golgi protein
MFLEKNFE_00708 8.58e-65 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
MFLEKNFE_00709 7.89e-124 - - - P - - - Cadmium resistance transporter
MFLEKNFE_00710 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_00711 0.0 - - - P - - - Concanavalin A-like lectin/glucanases superfamily
MFLEKNFE_00712 2.03e-84 - - - - - - - -
MFLEKNFE_00713 1.93e-205 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
MFLEKNFE_00714 2.86e-72 - - - - - - - -
MFLEKNFE_00715 1.02e-193 - - - K - - - Helix-turn-helix domain
MFLEKNFE_00716 3.91e-100 pts23A - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MFLEKNFE_00717 7.47e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MFLEKNFE_00718 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFLEKNFE_00719 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MFLEKNFE_00720 7.48e-236 - - - GM - - - Male sterility protein
MFLEKNFE_00721 4.4e-101 - - - K - - - helix_turn_helix, mercury resistance
MFLEKNFE_00722 1.32e-100 - - - M - - - LysM domain
MFLEKNFE_00723 3.03e-130 - - - M - - - Lysin motif
MFLEKNFE_00724 1.4e-138 - - - S - - - SdpI/YhfL protein family
MFLEKNFE_00725 1.58e-72 nudA - - S - - - ASCH
MFLEKNFE_00726 5.76e-212 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MFLEKNFE_00727 3.57e-120 - - - - - - - -
MFLEKNFE_00728 1.92e-155 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
MFLEKNFE_00729 2.92e-280 - - - T - - - diguanylate cyclase
MFLEKNFE_00730 7.43e-97 - - - S - - - Psort location Cytoplasmic, score
MFLEKNFE_00731 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
MFLEKNFE_00732 1.17e-214 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
MFLEKNFE_00733 5.26e-96 - - - - - - - -
MFLEKNFE_00734 6.54e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLEKNFE_00735 5.37e-222 - - - C - - - C4-dicarboxylate transmembrane transporter activity
MFLEKNFE_00736 2.51e-150 - - - GM - - - NAD(P)H-binding
MFLEKNFE_00737 1.6e-118 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MFLEKNFE_00738 5.51e-101 yphH - - S - - - Cupin domain
MFLEKNFE_00739 2.06e-78 - - - I - - - sulfurtransferase activity
MFLEKNFE_00740 5.44e-178 gdh 1.1.1.47, 1.1.1.53 - IQ ko:K00034,ko:K00038 ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200 ko00000,ko00001,ko01000 reductase
MFLEKNFE_00741 3.41e-151 - - - GM - - - NAD(P)H-binding
MFLEKNFE_00742 2.31e-277 - - - - - - - -
MFLEKNFE_00754 3.26e-119 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
MFLEKNFE_00755 1.28e-236 - - - P ko:K06901 - ko00000,ko02000 secondary active sulfate transmembrane transporter activity
MFLEKNFE_00756 1.25e-124 - - - - - - - -
MFLEKNFE_00757 9.14e-122 - - - K - - - Acetyltransferase (GNAT) domain
MFLEKNFE_00758 1.46e-200 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
MFLEKNFE_00760 8.93e-291 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MFLEKNFE_00761 2.95e-239 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MFLEKNFE_00762 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MFLEKNFE_00763 6.48e-215 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
MFLEKNFE_00764 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MFLEKNFE_00765 5.79e-158 - - - - - - - -
MFLEKNFE_00766 2.78e-273 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MFLEKNFE_00767 0.0 mdr - - EGP - - - Major Facilitator
MFLEKNFE_00768 3.98e-307 - - - N - - - Cell shape-determining protein MreB
MFLEKNFE_00769 0.0 - - - S - - - Pfam Methyltransferase
MFLEKNFE_00770 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MFLEKNFE_00771 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MFLEKNFE_00772 2.68e-39 - - - - - - - -
MFLEKNFE_00773 7.15e-121 mraW1 - - J - - - Putative rRNA methylase
MFLEKNFE_00774 2.07e-160 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MFLEKNFE_00775 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MFLEKNFE_00776 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MFLEKNFE_00777 5.04e-176 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MFLEKNFE_00778 5.24e-194 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MFLEKNFE_00779 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MFLEKNFE_00780 2.16e-109 - - - T - - - Belongs to the universal stress protein A family
MFLEKNFE_00781 1.02e-258 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
MFLEKNFE_00782 2.27e-221 ugpA - - U ko:K02025,ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFLEKNFE_00783 3.05e-193 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFLEKNFE_00784 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MFLEKNFE_00785 5.45e-162 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MFLEKNFE_00786 2.07e-155 dgk2 - - F - - - deoxynucleoside kinase
MFLEKNFE_00787 3.55e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MFLEKNFE_00788 0.0 XK27_06930 - - V ko:K01421 - ko00000 domain protein
MFLEKNFE_00790 3.63e-164 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
MFLEKNFE_00791 3.06e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MFLEKNFE_00792 2.57e-226 - - - K ko:K01990 - ko00000,ko00002,ko02000 LytTr DNA-binding domain
MFLEKNFE_00793 4.03e-197 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MFLEKNFE_00794 5.2e-85 - - - K - - - helix_turn_helix, mercury resistance
MFLEKNFE_00795 1.64e-151 - - - GM - - - NAD(P)H-binding
MFLEKNFE_00796 4.58e-56 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MFLEKNFE_00797 7.16e-107 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MFLEKNFE_00798 1.97e-191 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MFLEKNFE_00799 1.3e-138 - - - - - - - -
MFLEKNFE_00800 2.08e-283 pltK 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MFLEKNFE_00801 9.01e-179 agrA - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MFLEKNFE_00802 5.37e-74 - - - - - - - -
MFLEKNFE_00803 4.56e-78 - - - - - - - -
MFLEKNFE_00804 1.23e-145 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
MFLEKNFE_00805 2.2e-111 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
MFLEKNFE_00806 2.95e-117 - - - - - - - -
MFLEKNFE_00807 7.12e-62 - - - - - - - -
MFLEKNFE_00808 0.0 uvrA2 - - L - - - ABC transporter
MFLEKNFE_00811 4.29e-87 - - - - - - - -
MFLEKNFE_00812 9.03e-16 - - - - - - - -
MFLEKNFE_00813 3.89e-237 - - - - - - - -
MFLEKNFE_00814 4.91e-117 gtcA1 - - S - - - Teichoic acid glycosylation protein
MFLEKNFE_00815 8.01e-77 - - - S - - - Protein of unknown function (DUF1516)
MFLEKNFE_00816 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MFLEKNFE_00817 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MFLEKNFE_00818 0.0 - - - S - - - Protein conserved in bacteria
MFLEKNFE_00819 5.16e-292 sat 2.7.7.4 - H ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
MFLEKNFE_00820 9.14e-146 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
MFLEKNFE_00821 1.79e-225 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
MFLEKNFE_00822 0.0 astA 2.8.2.22 - M ko:K01023 - ko00000,ko01000 Arylsulfotransferase Ig-like domain
MFLEKNFE_00823 0.0 - - - P - - - Sodium:sulfate symporter transmembrane region
MFLEKNFE_00824 2.69e-316 dinF - - V - - - MatE
MFLEKNFE_00825 1.79e-42 - - - - - - - -
MFLEKNFE_00828 3.48e-103 yybD - - S ko:K02348 - ko00000 Acetyltransferase (GNAT) domain
MFLEKNFE_00829 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MFLEKNFE_00830 4.64e-106 - - - - - - - -
MFLEKNFE_00831 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MFLEKNFE_00832 6.25e-138 - - - - - - - -
MFLEKNFE_00833 0.0 celR - - K - - - PRD domain
MFLEKNFE_00834 2.7e-104 - - - S - - - Domain of unknown function (DUF3284)
MFLEKNFE_00835 2.37e-68 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MFLEKNFE_00836 4.9e-64 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MFLEKNFE_00837 1.5e-310 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFLEKNFE_00838 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MFLEKNFE_00839 1.28e-263 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
MFLEKNFE_00840 1.72e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
MFLEKNFE_00841 1.65e-46 dltC2 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFLEKNFE_00842 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 Alanine-glyoxylate amino-transferase
MFLEKNFE_00843 3.29e-132 argO - - S ko:K06895 - ko00000,ko02000 LysE type translocator
MFLEKNFE_00844 2.77e-271 arcT - - E - - - Aminotransferase
MFLEKNFE_00845 2.07e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MFLEKNFE_00846 2.43e-18 - - - - - - - -
MFLEKNFE_00847 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MFLEKNFE_00848 9.94e-71 yheA - - S - - - Belongs to the UPF0342 family
MFLEKNFE_00849 4.47e-296 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
MFLEKNFE_00850 0.0 yhaN - - L - - - AAA domain
MFLEKNFE_00851 1.03e-240 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
MFLEKNFE_00852 7.82e-278 - - - - - - - -
MFLEKNFE_00853 1.39e-232 - - - M - - - Peptidase family S41
MFLEKNFE_00854 6.59e-227 - - - K - - - LysR substrate binding domain
MFLEKNFE_00855 9.9e-144 - - - S - - - NADPH-dependent FMN reductase
MFLEKNFE_00856 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MFLEKNFE_00857 8.59e-127 - - - - - - - -
MFLEKNFE_00858 3.36e-100 - 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside 2-deoxyribosyltransferase
MFLEKNFE_00859 5.27e-203 - - - T - - - Histidine kinase
MFLEKNFE_00860 1.73e-134 llrE - - K - - - Transcriptional regulatory protein, C terminal
MFLEKNFE_00861 7.93e-79 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
MFLEKNFE_00862 2.26e-167 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
MFLEKNFE_00863 1.18e-100 - - - S ko:K03975 - ko00000 SNARE-like domain protein
MFLEKNFE_00864 3.3e-235 ykoT - - M - - - Glycosyl transferase family 2
MFLEKNFE_00865 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MFLEKNFE_00866 5.72e-90 - - - S - - - NUDIX domain
MFLEKNFE_00867 0.0 - - - S - - - membrane
MFLEKNFE_00868 1.22e-217 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MFLEKNFE_00869 8.71e-111 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
MFLEKNFE_00870 4.2e-284 ribA 3.5.4.25, 4.1.99.12 - H ko:K02858,ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MFLEKNFE_00871 1.23e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MFLEKNFE_00872 5.21e-137 - - - S ko:K09962 - ko00000 Nucleotidyltransferase
MFLEKNFE_00873 3.39e-138 - - - - - - - -
MFLEKNFE_00874 2.71e-150 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
MFLEKNFE_00875 4.89e-146 - - - K - - - Bacterial regulatory proteins, tetR family
MFLEKNFE_00876 2.11e-308 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
MFLEKNFE_00877 0.0 - - - - - - - -
MFLEKNFE_00878 4.75e-80 - - - - - - - -
MFLEKNFE_00879 3.36e-248 - - - S - - - Fn3-like domain
MFLEKNFE_00880 2.82e-138 - - - S - - - WxL domain surface cell wall-binding
MFLEKNFE_00881 5.76e-135 - - - S - - - WxL domain surface cell wall-binding
MFLEKNFE_00882 1.09e-196 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MFLEKNFE_00883 7.9e-72 - - - - - - - -
MFLEKNFE_00884 3.6e-106 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
MFLEKNFE_00885 1.1e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_00886 8.17e-285 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MFLEKNFE_00887 7.24e-197 ytmP - - M - - - Choline/ethanolamine kinase
MFLEKNFE_00888 4.7e-156 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MFLEKNFE_00889 2.94e-71 ytzB - - S - - - Peptidase propeptide and YPEB domain
MFLEKNFE_00890 1.45e-145 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MFLEKNFE_00891 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MFLEKNFE_00892 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MFLEKNFE_00893 3.04e-29 - - - S - - - Virus attachment protein p12 family
MFLEKNFE_00894 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
MFLEKNFE_00895 2.87e-47 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
MFLEKNFE_00896 1.1e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MFLEKNFE_00897 8.63e-310 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
MFLEKNFE_00898 1.83e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MFLEKNFE_00899 2.71e-108 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
MFLEKNFE_00900 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MFLEKNFE_00901 4.07e-60 - - - S - - - Iron-sulfur cluster assembly protein
MFLEKNFE_00902 1.04e-141 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MFLEKNFE_00903 8.51e-155 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MFLEKNFE_00904 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MFLEKNFE_00905 3.19e-202 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MFLEKNFE_00906 3.88e-133 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MFLEKNFE_00907 1.58e-117 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MFLEKNFE_00908 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
MFLEKNFE_00909 6.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MFLEKNFE_00910 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MFLEKNFE_00911 2.37e-109 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MFLEKNFE_00912 6.92e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MFLEKNFE_00913 6.88e-73 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MFLEKNFE_00914 2.76e-74 - - - - - - - -
MFLEKNFE_00915 8.2e-306 - - - L ko:K07478 - ko00000 AAA C-terminal domain
MFLEKNFE_00916 7.09e-252 qor 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MFLEKNFE_00917 1.64e-83 ydeP - - K - - - Transcriptional regulator, HxlR family
MFLEKNFE_00918 9.75e-175 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MFLEKNFE_00919 0.0 pflD 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
MFLEKNFE_00920 4.3e-228 - - - K - - - sugar-binding domain protein
MFLEKNFE_00921 1.81e-160 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
MFLEKNFE_00922 2.13e-182 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MFLEKNFE_00923 2.89e-224 ccpB - - K - - - lacI family
MFLEKNFE_00924 1.51e-202 - - - K - - - Helix-turn-helix domain, rpiR family
MFLEKNFE_00925 5e-227 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MFLEKNFE_00926 1.89e-254 yhhX - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
MFLEKNFE_00927 0.0 nhaP2 - - P ko:K03316 - ko00000 Sodium proton antiporter
MFLEKNFE_00928 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MFLEKNFE_00929 9.38e-139 pncA - - Q - - - Isochorismatase family
MFLEKNFE_00930 2.66e-172 - - - - - - - -
MFLEKNFE_00931 5e-162 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MFLEKNFE_00932 8.34e-86 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
MFLEKNFE_00933 7.2e-61 - - - S - - - Enterocin A Immunity
MFLEKNFE_00934 3.25e-223 ybcH - - D ko:K06889 - ko00000 Alpha beta
MFLEKNFE_00935 0.0 pepF2 - - E - - - Oligopeptidase F
MFLEKNFE_00936 1.4e-95 - - - K - - - Transcriptional regulator
MFLEKNFE_00937 1.53e-209 - - - - - - - -
MFLEKNFE_00938 1.23e-75 - - - - - - - -
MFLEKNFE_00939 1.44e-65 - - - - - - - -
MFLEKNFE_00940 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MFLEKNFE_00941 4.09e-89 - - - - - - - -
MFLEKNFE_00942 1.19e-186 - - - S ko:K06889 - ko00000 Dienelactone hydrolase family
MFLEKNFE_00943 2.84e-73 ytpP - - CO - - - Thioredoxin
MFLEKNFE_00944 5.5e-262 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
MFLEKNFE_00945 3.89e-62 - - - - - - - -
MFLEKNFE_00946 1.57e-71 - - - - - - - -
MFLEKNFE_00947 6.94e-106 - - - S - - - Protein of unknown function (DUF2798)
MFLEKNFE_00948 1.65e-97 - - - - - - - -
MFLEKNFE_00949 4.15e-78 - - - - - - - -
MFLEKNFE_00950 4.26e-250 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MFLEKNFE_00951 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Bacterial SH3 domain
MFLEKNFE_00952 1.63e-95 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MFLEKNFE_00953 3.82e-188 agaD - - G ko:K02747,ko:K02796,ko:K10986 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MFLEKNFE_00954 5.2e-185 - - - G ko:K02746,ko:K10985 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MFLEKNFE_00955 1.49e-112 - 2.7.1.191 - K ko:K02745,ko:K02794,ko:K10984 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MFLEKNFE_00956 5.87e-166 - - - K ko:K03710 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MFLEKNFE_00957 2.51e-103 uspA3 - - T - - - universal stress protein
MFLEKNFE_00958 3.04e-204 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MFLEKNFE_00959 4.05e-64 - - - K - - - Cro/C1-type HTH DNA-binding domain
MFLEKNFE_00960 1.38e-30 - - - S - - - Protein of unknown function (DUF2929)
MFLEKNFE_00961 3.07e-284 - - - M - - - Glycosyl transferases group 1
MFLEKNFE_00962 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MFLEKNFE_00963 3.74e-205 - - - S - - - Putative esterase
MFLEKNFE_00964 3.53e-169 - - - K - - - Transcriptional regulator
MFLEKNFE_00965 4.75e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MFLEKNFE_00966 1.74e-178 - - - - - - - -
MFLEKNFE_00967 4.85e-151 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MFLEKNFE_00968 8.05e-179 rrp8 - - K - - - LytTr DNA-binding domain
MFLEKNFE_00969 1.7e-118 - - - K - - - Domain of unknown function (DUF1836)
MFLEKNFE_00970 1.27e-78 - - - - - - - -
MFLEKNFE_00971 7.48e-96 hsp2 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MFLEKNFE_00972 2.97e-76 - - - - - - - -
MFLEKNFE_00973 0.0 yhdP - - S - - - Transporter associated domain
MFLEKNFE_00974 1.18e-114 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
MFLEKNFE_00975 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
MFLEKNFE_00976 1.17e-270 yttB - - EGP - - - Major Facilitator
MFLEKNFE_00977 4.71e-81 - - - K - - - helix_turn_helix, mercury resistance
MFLEKNFE_00978 8.91e-220 - - - C - - - Zinc-binding dehydrogenase
MFLEKNFE_00979 4.71e-74 - - - S - - - SdpI/YhfL protein family
MFLEKNFE_00980 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MFLEKNFE_00981 0.0 gabR - - K ko:K00375 - ko00000,ko03000 Bacterial regulatory proteins, gntR family
MFLEKNFE_00982 2.91e-277 araT2 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MFLEKNFE_00983 1.46e-131 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MFLEKNFE_00984 3.59e-26 - - - - - - - -
MFLEKNFE_00985 2.09e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
MFLEKNFE_00986 5.73e-208 mleR - - K - - - LysR family
MFLEKNFE_00987 1.29e-148 - - - GM - - - NAD(P)H-binding
MFLEKNFE_00988 3.86e-124 - - - K - - - Acetyltransferase (GNAT) family
MFLEKNFE_00989 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MFLEKNFE_00990 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MFLEKNFE_00991 5.46e-218 oroP - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
MFLEKNFE_00992 6.64e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MFLEKNFE_00993 4.44e-161 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MFLEKNFE_00994 4.24e-218 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MFLEKNFE_00995 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MFLEKNFE_00996 2.36e-272 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MFLEKNFE_00997 1.95e-309 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MFLEKNFE_00998 1.22e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MFLEKNFE_00999 7.13e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MFLEKNFE_01000 0.0 pucR_2 - - QT ko:K09684 - ko00000,ko03000 Purine catabolism regulatory protein-like family
MFLEKNFE_01001 3.1e-305 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MFLEKNFE_01002 5.67e-280 pbuG - - S ko:K06901 - ko00000,ko02000 Permease family
MFLEKNFE_01003 2.24e-206 - - - GM - - - NmrA-like family
MFLEKNFE_01004 1.25e-199 - - - T - - - EAL domain
MFLEKNFE_01005 2.62e-121 - - - - - - - -
MFLEKNFE_01006 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
MFLEKNFE_01007 9.84e-162 - - - E - - - Methionine synthase
MFLEKNFE_01008 2.71e-280 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MFLEKNFE_01009 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MFLEKNFE_01010 5.35e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MFLEKNFE_01011 5.35e-246 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MFLEKNFE_01012 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MFLEKNFE_01013 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFLEKNFE_01014 6.91e-164 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFLEKNFE_01015 1.17e-55 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFLEKNFE_01016 3.39e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MFLEKNFE_01017 1e-270 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MFLEKNFE_01018 3.77e-104 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MFLEKNFE_01019 7.9e-305 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
MFLEKNFE_01020 9.92e-143 - - - S - - - NADPH-dependent FMN reductase
MFLEKNFE_01021 2.01e-243 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
MFLEKNFE_01022 2.04e-189 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MFLEKNFE_01023 5.95e-153 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
MFLEKNFE_01024 4.15e-191 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MFLEKNFE_01025 3.7e-233 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
MFLEKNFE_01026 2.05e-178 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_01027 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MFLEKNFE_01028 4.76e-56 - - - - - - - -
MFLEKNFE_01029 8.2e-81 - - - K - - - Transcriptional regulator, GntR family
MFLEKNFE_01030 7.89e-212 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_01031 3.41e-190 - - - - - - - -
MFLEKNFE_01032 2.7e-104 usp5 - - T - - - universal stress protein
MFLEKNFE_01033 7.35e-46 - - - - - - - -
MFLEKNFE_01034 4.02e-95 gtcA - - S - - - Teichoic acid glycosylation protein
MFLEKNFE_01035 1.76e-114 - - - - - - - -
MFLEKNFE_01036 4.87e-66 - - - - - - - -
MFLEKNFE_01037 4.79e-13 - - - - - - - -
MFLEKNFE_01038 3.03e-299 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MFLEKNFE_01039 1.16e-110 - - - F - - - belongs to the nudix hydrolase family
MFLEKNFE_01040 1.52e-151 - - - - - - - -
MFLEKNFE_01041 1.21e-69 - - - - - - - -
MFLEKNFE_01042 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MFLEKNFE_01043 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
MFLEKNFE_01044 4.65e-186 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MFLEKNFE_01045 2.96e-41 - - - S - - - Pentapeptide repeats (8 copies)
MFLEKNFE_01046 1.76e-143 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MFLEKNFE_01047 2.28e-132 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
MFLEKNFE_01048 2.26e-91 - - - FG - - - Scavenger mRNA decapping enzyme C-term binding
MFLEKNFE_01049 1.62e-173 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MFLEKNFE_01050 3.94e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
MFLEKNFE_01051 9.97e-269 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MFLEKNFE_01052 4.43e-294 - - - S - - - Sterol carrier protein domain
MFLEKNFE_01053 1.58e-285 - - - EGP - - - Transmembrane secretion effector
MFLEKNFE_01054 3.74e-115 yrxA - - S ko:K07105 - ko00000 3H domain
MFLEKNFE_01055 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MFLEKNFE_01056 2.13e-152 - - - K - - - Transcriptional regulator
MFLEKNFE_01057 9.76e-234 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MFLEKNFE_01058 4.29e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MFLEKNFE_01059 9.53e-317 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
MFLEKNFE_01060 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MFLEKNFE_01061 0.0 pbg5 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MFLEKNFE_01062 6.7e-74 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
MFLEKNFE_01063 1.86e-64 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MFLEKNFE_01064 7.44e-168 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
MFLEKNFE_01065 1.4e-181 epsV - - S - - - glycosyl transferase family 2
MFLEKNFE_01066 1.75e-156 pgm7 - - G - - - Phosphoglycerate mutase family
MFLEKNFE_01067 7.63e-107 - - - - - - - -
MFLEKNFE_01068 5.06e-196 - - - S - - - hydrolase
MFLEKNFE_01069 1.51e-235 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MFLEKNFE_01070 2.8e-204 - - - EG - - - EamA-like transporter family
MFLEKNFE_01071 4.12e-226 serA1 - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MFLEKNFE_01072 3.78e-132 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MFLEKNFE_01073 0.0 - - - - ko:K21471 - ko00000,ko01000,ko01002,ko01011 -
MFLEKNFE_01074 1.17e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
MFLEKNFE_01075 0.0 - - - M - - - Domain of unknown function (DUF5011)
MFLEKNFE_01076 1.08e-81 - - - M - - - Domain of unknown function (DUF5011)
MFLEKNFE_01077 0.0 - - - M - - - Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
MFLEKNFE_01078 4.3e-44 - - - - - - - -
MFLEKNFE_01079 5.59e-163 aroC1 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
MFLEKNFE_01080 0.0 ycaM - - E - - - amino acid
MFLEKNFE_01081 2e-100 - - - K - - - Winged helix DNA-binding domain
MFLEKNFE_01082 8.21e-212 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
MFLEKNFE_01083 5.11e-208 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MFLEKNFE_01084 1.77e-207 - - - K - - - Transcriptional regulator
MFLEKNFE_01086 3.55e-94 - - - NU - - - Mycoplasma protein of unknown function, DUF285
MFLEKNFE_01087 2.4e-152 - - - K - - - Bacterial regulatory proteins, tetR family
MFLEKNFE_01088 0.0 lepA2 - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MFLEKNFE_01089 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
MFLEKNFE_01090 4.54e-202 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 NADH pyrophosphatase zinc ribbon domain
MFLEKNFE_01091 1.16e-209 - - - K - - - LysR substrate binding domain
MFLEKNFE_01092 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MFLEKNFE_01093 0.0 - - - S - - - MucBP domain
MFLEKNFE_01094 9.82e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
MFLEKNFE_01095 1.9e-148 - - - K ko:K03489 - ko00000,ko03000 UTRA
MFLEKNFE_01096 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MFLEKNFE_01097 9.2e-317 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFLEKNFE_01098 2.09e-85 - - - - - - - -
MFLEKNFE_01099 5.15e-16 - - - - - - - -
MFLEKNFE_01100 5.61e-54 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MFLEKNFE_01101 4.83e-31 - - - K - - - helix_turn_helix, mercury resistance
MFLEKNFE_01102 5.98e-85 - - - S - - - Protein of unknown function (DUF1093)
MFLEKNFE_01103 8.12e-282 - - - S - - - Membrane
MFLEKNFE_01104 2.97e-59 - - - S - - - Protein of unknown function (DUF3781)
MFLEKNFE_01105 5.35e-139 yoaZ - - S - - - intracellular protease amidase
MFLEKNFE_01106 1.35e-55 - - - K - - - HxlR-like helix-turn-helix
MFLEKNFE_01107 1.92e-76 - - - - - - - -
MFLEKNFE_01108 2.06e-81 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MFLEKNFE_01109 5.31e-66 - - - K - - - Helix-turn-helix domain
MFLEKNFE_01110 9.09e-260 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
MFLEKNFE_01111 3.64e-47 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MFLEKNFE_01112 1.44e-148 yciB - - M - - - ErfK YbiS YcfS YnhG
MFLEKNFE_01113 8.09e-142 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MFLEKNFE_01114 1.93e-139 - - - GM - - - NAD(P)H-binding
MFLEKNFE_01115 5.35e-102 - - - GM - - - SnoaL-like domain
MFLEKNFE_01116 0.0 qacA - - EGP - - - Fungal trichothecene efflux pump (TRI12)
MFLEKNFE_01117 2.95e-84 - - - S - - - Domain of unknown function (DUF4440)
MFLEKNFE_01118 7.9e-136 - - - K - - - Bacterial regulatory proteins, tetR family
MFLEKNFE_01119 1.34e-05 - - - L ko:K07483 - ko00000 transposase activity
MFLEKNFE_01120 8.53e-45 - - - L ko:K07483 - ko00000 transposase activity
MFLEKNFE_01122 6.79e-53 - - - - - - - -
MFLEKNFE_01123 5.06e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MFLEKNFE_01124 9.26e-233 ydbI - - K - - - AI-2E family transporter
MFLEKNFE_01125 7.62e-270 xylR - - GK - - - ROK family
MFLEKNFE_01126 4.93e-149 - - - - - - - -
MFLEKNFE_01127 3.66e-295 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MFLEKNFE_01128 1.41e-211 - - - - - - - -
MFLEKNFE_01129 1.66e-259 pkn2 - - KLT - - - Protein tyrosine kinase
MFLEKNFE_01130 5.03e-37 - - - S - - - Protein of unknown function (DUF4064)
MFLEKNFE_01131 2.47e-125 - - - S - - - Domain of unknown function (DUF4352)
MFLEKNFE_01132 7.97e-98 - - - S - - - Psort location Cytoplasmic, score
MFLEKNFE_01133 2.12e-72 - - - - - - - -
MFLEKNFE_01134 1.18e-141 - - - S ko:K07090 - ko00000 membrane transporter protein
MFLEKNFE_01135 5.93e-73 - - - S - - - branched-chain amino acid
MFLEKNFE_01136 2.05e-167 - - - E - - - branched-chain amino acid
MFLEKNFE_01137 1.66e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MFLEKNFE_01138 5.36e-305 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MFLEKNFE_01139 5.61e-273 hpk31 - - T - - - Histidine kinase
MFLEKNFE_01140 1.14e-159 vanR - - K - - - response regulator
MFLEKNFE_01141 2.4e-161 - - - S - - - Protein of unknown function (DUF1275)
MFLEKNFE_01142 3.84e-207 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MFLEKNFE_01143 3.49e-270 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MFLEKNFE_01144 3.49e-160 - - - S - - - Protein of unknown function (DUF1129)
MFLEKNFE_01145 6.6e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MFLEKNFE_01146 1.4e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MFLEKNFE_01147 3.98e-200 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MFLEKNFE_01148 1.01e-175 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
MFLEKNFE_01149 3.01e-191 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MFLEKNFE_01150 3.66e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MFLEKNFE_01151 1.66e-288 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
MFLEKNFE_01152 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MFLEKNFE_01153 1.56e-190 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MFLEKNFE_01154 3.36e-216 - - - K - - - LysR substrate binding domain
MFLEKNFE_01155 5.69e-300 - - - EK - - - Aminotransferase, class I
MFLEKNFE_01156 1.11e-169 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MFLEKNFE_01157 2.11e-158 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFLEKNFE_01158 3.02e-176 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_01159 1.26e-161 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MFLEKNFE_01160 8.83e-127 - - - KT - - - response to antibiotic
MFLEKNFE_01161 8.52e-70 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
MFLEKNFE_01162 6.03e-133 - - - S - - - Protein of unknown function (DUF1700)
MFLEKNFE_01163 9.68e-202 - - - S - - - Putative adhesin
MFLEKNFE_01164 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFLEKNFE_01165 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MFLEKNFE_01166 1.06e-232 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
MFLEKNFE_01167 4.35e-262 - - - S - - - DUF218 domain
MFLEKNFE_01168 9.95e-165 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MFLEKNFE_01169 1.76e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_01170 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MFLEKNFE_01171 3.62e-100 - - - - - - - -
MFLEKNFE_01172 5.43e-194 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
MFLEKNFE_01173 8.33e-189 - - - S - - - haloacid dehalogenase-like hydrolase
MFLEKNFE_01174 1.29e-115 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MFLEKNFE_01175 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
MFLEKNFE_01176 6.69e-155 fptC - - U ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase system, EIIC
MFLEKNFE_01177 2.52e-35 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MFLEKNFE_01178 5.55e-22 - - - G ko:K11203 - ko00000,ko00002,ko02000 PTS system, fructose subfamily
MFLEKNFE_01179 2.11e-104 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MFLEKNFE_01180 4.08e-101 - - - K - - - MerR family regulatory protein
MFLEKNFE_01181 2.16e-199 - - - GM - - - NmrA-like family
MFLEKNFE_01182 0.0 pts28ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFLEKNFE_01183 5.93e-163 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
MFLEKNFE_01185 8.66e-130 - - - S - - - NADPH-dependent FMN reductase
MFLEKNFE_01186 3.43e-303 - - - S - - - module of peptide synthetase
MFLEKNFE_01187 4.71e-135 - - - - - - - -
MFLEKNFE_01188 1.55e-114 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MFLEKNFE_01189 7.43e-77 - - - S - - - Enterocin A Immunity
MFLEKNFE_01190 6.46e-49 - - - S - - - Phospholipase_D-nuclease N-terminal
MFLEKNFE_01191 1.26e-213 - 3.1.4.17, 3.1.4.53 - S ko:K01120,ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
MFLEKNFE_01192 2.8e-135 - - - J - - - Acetyltransferase (GNAT) domain
MFLEKNFE_01193 9.76e-83 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
MFLEKNFE_01194 2.88e-164 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
MFLEKNFE_01195 1.9e-186 WQ51_01275 - - S - - - EDD domain protein, DegV family
MFLEKNFE_01196 1.03e-34 - - - - - - - -
MFLEKNFE_01197 4.23e-152 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
MFLEKNFE_01198 0.0 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
MFLEKNFE_01199 1.72e-211 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
MFLEKNFE_01200 4.68e-235 - - - D ko:K06889 - ko00000 Alpha beta
MFLEKNFE_01201 5.81e-251 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MFLEKNFE_01202 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MFLEKNFE_01203 2.49e-73 - - - S - - - Enterocin A Immunity
MFLEKNFE_01204 7.41e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MFLEKNFE_01205 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MFLEKNFE_01206 7.21e-236 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MFLEKNFE_01207 1.45e-187 ptp2 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MFLEKNFE_01208 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFLEKNFE_01210 1.09e-105 - - - - - - - -
MFLEKNFE_01211 0.0 yhdG - - E ko:K03294 - ko00000 C-terminus of AA_permease
MFLEKNFE_01213 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MFLEKNFE_01214 1.07e-211 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MFLEKNFE_01215 1.54e-228 ydbI - - K - - - AI-2E family transporter
MFLEKNFE_01216 1.01e-277 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MFLEKNFE_01217 1.15e-77 - - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
MFLEKNFE_01218 1.97e-60 qacH - - U ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
MFLEKNFE_01219 2.94e-149 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MFLEKNFE_01220 7.27e-73 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MFLEKNFE_01221 1.3e-207 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
MFLEKNFE_01222 3.28e-133 - - - K - - - Helix-turn-helix XRE-family like proteins
MFLEKNFE_01224 2.77e-30 - - - - - - - -
MFLEKNFE_01226 3.91e-124 tag2 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MFLEKNFE_01227 4.79e-272 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
MFLEKNFE_01228 4.4e-138 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
MFLEKNFE_01229 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MFLEKNFE_01230 1.8e-134 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
MFLEKNFE_01231 1.59e-121 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MFLEKNFE_01232 9.61e-84 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MFLEKNFE_01233 4.26e-109 cvpA - - S - - - Colicin V production protein
MFLEKNFE_01234 5.61e-216 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MFLEKNFE_01235 4.41e-316 - - - EGP - - - Major Facilitator
MFLEKNFE_01237 4.54e-54 - - - - - - - -
MFLEKNFE_01239 2.41e-05 - - - L ko:K07483 - ko00000 transposase activity
MFLEKNFE_01240 1.75e-43 - - - - - - - -
MFLEKNFE_01241 1.02e-183 - - - Q - - - Methyltransferase
MFLEKNFE_01242 2.84e-75 ybjQ - - S - - - Belongs to the UPF0145 family
MFLEKNFE_01243 2.87e-270 - - - EGP - - - Major facilitator Superfamily
MFLEKNFE_01244 4.57e-135 - - - K - - - Helix-turn-helix domain
MFLEKNFE_01245 1.52e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MFLEKNFE_01246 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MFLEKNFE_01247 1.84e-67 - - - S - - - Lipopolysaccharide assembly protein A domain
MFLEKNFE_01248 7.93e-177 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLEKNFE_01249 2.05e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MFLEKNFE_01250 6.62e-62 - - - - - - - -
MFLEKNFE_01251 1.55e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MFLEKNFE_01252 3.02e-175 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MFLEKNFE_01253 4.24e-218 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MFLEKNFE_01254 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
MFLEKNFE_01255 0.0 - 3.1.4.53 - S ko:K03651 ko00230,ko02025,map00230,map02025 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
MFLEKNFE_01256 0.0 cps4J - - S - - - MatE
MFLEKNFE_01257 4.82e-228 cps4I - - M - - - Glycosyltransferase like family 2
MFLEKNFE_01258 2.32e-298 - - - - - - - -
MFLEKNFE_01259 1.94e-244 cps4G - - M - - - Glycosyltransferase Family 4
MFLEKNFE_01260 1.4e-259 cps4F - - M - - - Glycosyl transferases group 1
MFLEKNFE_01261 2.33e-164 tuaA - - M - - - Bacterial sugar transferase
MFLEKNFE_01262 8.71e-231 cps4D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
MFLEKNFE_01263 5.54e-189 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MFLEKNFE_01264 4.97e-157 ywqD - - D - - - Capsular exopolysaccharide family
MFLEKNFE_01265 8.45e-162 epsB - - M - - - biosynthesis protein
MFLEKNFE_01266 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MFLEKNFE_01267 3.97e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_01268 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MFLEKNFE_01269 5.12e-31 - - - - - - - -
MFLEKNFE_01270 6.47e-95 - - - S - - - Iron-sulphur cluster biosynthesis
MFLEKNFE_01271 1.3e-65 - - - S - - - mazG nucleotide pyrophosphohydrolase
MFLEKNFE_01272 9.6e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MFLEKNFE_01273 7.8e-300 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MFLEKNFE_01274 6.48e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MFLEKNFE_01275 4.38e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MFLEKNFE_01276 2.8e-202 - - - S - - - Tetratricopeptide repeat
MFLEKNFE_01277 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MFLEKNFE_01278 5.25e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MFLEKNFE_01279 3.84e-262 - - - EGP - - - Major Facilitator Superfamily
MFLEKNFE_01280 2.9e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MFLEKNFE_01281 1.18e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MFLEKNFE_01282 5.09e-241 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MFLEKNFE_01283 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MFLEKNFE_01284 7.1e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MFLEKNFE_01285 2.56e-162 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MFLEKNFE_01286 1.05e-251 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MFLEKNFE_01287 2.99e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MFLEKNFE_01288 4.98e-131 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MFLEKNFE_01289 1.91e-66 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
MFLEKNFE_01290 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MFLEKNFE_01291 2.51e-261 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MFLEKNFE_01292 0.0 - - - - - - - -
MFLEKNFE_01293 0.0 icaA - - M - - - Glycosyl transferase family group 2
MFLEKNFE_01294 9.51e-135 - - - - - - - -
MFLEKNFE_01295 9.43e-259 - - - - - - - -
MFLEKNFE_01296 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MFLEKNFE_01297 1.23e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
MFLEKNFE_01298 2.64e-62 yktA - - S - - - Belongs to the UPF0223 family
MFLEKNFE_01299 2.15e-209 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
MFLEKNFE_01300 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
MFLEKNFE_01301 2.36e-285 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MFLEKNFE_01302 6.35e-230 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
MFLEKNFE_01303 7.02e-268 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
MFLEKNFE_01304 3.95e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MFLEKNFE_01305 6.45e-111 - - - - - - - -
MFLEKNFE_01306 4.86e-45 ykzG - - S - - - Belongs to the UPF0356 family
MFLEKNFE_01307 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MFLEKNFE_01308 5.96e-241 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MFLEKNFE_01309 2.16e-39 - - - - - - - -
MFLEKNFE_01310 2.62e-168 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MFLEKNFE_01311 5.35e-220 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MFLEKNFE_01312 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MFLEKNFE_01313 5.87e-155 - - - S - - - repeat protein
MFLEKNFE_01314 2.41e-157 pgm6 - - G - - - phosphoglycerate mutase
MFLEKNFE_01315 0.0 - - - N - - - domain, Protein
MFLEKNFE_01316 1.22e-248 - - - S - - - Bacterial protein of unknown function (DUF916)
MFLEKNFE_01317 4.17e-153 - - - N - - - WxL domain surface cell wall-binding
MFLEKNFE_01318 4.64e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
MFLEKNFE_01319 9.64e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
MFLEKNFE_01320 3.19e-285 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MFLEKNFE_01321 4.94e-75 XK27_04120 - - S - - - Putative amino acid metabolism
MFLEKNFE_01322 3.69e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MFLEKNFE_01323 5.85e-158 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MFLEKNFE_01324 7.74e-47 - - - - - - - -
MFLEKNFE_01325 3.51e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MFLEKNFE_01326 1.41e-241 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MFLEKNFE_01327 2.05e-20 - - - S - - - Protein of unknown function (DUF3021)
MFLEKNFE_01328 2.57e-47 - - - K - - - LytTr DNA-binding domain
MFLEKNFE_01329 1.47e-100 - - - U ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
MFLEKNFE_01330 3.64e-101 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
MFLEKNFE_01331 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MFLEKNFE_01332 6.52e-124 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
MFLEKNFE_01333 2.06e-187 ylmH - - S - - - S4 domain protein
MFLEKNFE_01334 6.45e-49 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
MFLEKNFE_01335 1.56e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MFLEKNFE_01336 9.39e-295 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MFLEKNFE_01337 3.55e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MFLEKNFE_01338 3.88e-207 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MFLEKNFE_01339 5e-253 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MFLEKNFE_01340 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MFLEKNFE_01341 2.81e-231 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MFLEKNFE_01342 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MFLEKNFE_01343 7.01e-76 ftsL - - D - - - Cell division protein FtsL
MFLEKNFE_01344 2.47e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MFLEKNFE_01345 7.24e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MFLEKNFE_01346 3.22e-82 - - - S - - - Protein of unknown function (DUF3397)
MFLEKNFE_01347 4.1e-223 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MFLEKNFE_01348 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MFLEKNFE_01349 4.73e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MFLEKNFE_01350 1.44e-146 - - - S ko:K07118 - ko00000 NAD(P)H-binding
MFLEKNFE_01351 2.17e-302 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MFLEKNFE_01353 1.12e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
MFLEKNFE_01354 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MFLEKNFE_01355 2.24e-262 XK27_05220 - - S - - - AI-2E family transporter
MFLEKNFE_01356 2.68e-75 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MFLEKNFE_01357 5.57e-247 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MFLEKNFE_01358 2.51e-150 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
MFLEKNFE_01359 1.09e-222 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MFLEKNFE_01360 5.27e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MFLEKNFE_01361 9.08e-157 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MFLEKNFE_01362 2.24e-148 yjbH - - Q - - - Thioredoxin
MFLEKNFE_01363 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MFLEKNFE_01364 2.73e-265 coiA - - S ko:K06198 - ko00000 Competence protein
MFLEKNFE_01365 7.12e-170 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MFLEKNFE_01366 9.28e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MFLEKNFE_01367 3.28e-177 yhfI - - S - - - Metallo-beta-lactamase superfamily
MFLEKNFE_01368 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
MFLEKNFE_01369 1.42e-08 - - - - - - - -
MFLEKNFE_01370 1.27e-115 - - - S - - - AAA domain
MFLEKNFE_01371 7.45e-180 - - - K - - - sequence-specific DNA binding
MFLEKNFE_01372 1.09e-123 - - - K - - - Helix-turn-helix domain
MFLEKNFE_01373 7.61e-218 - - - K - - - Transcriptional regulator
MFLEKNFE_01374 0.0 - - - C - - - FMN_bind
MFLEKNFE_01376 3.54e-105 - - - K - - - Transcriptional regulator
MFLEKNFE_01377 4.71e-149 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MFLEKNFE_01378 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MFLEKNFE_01379 3.39e-255 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
MFLEKNFE_01380 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MFLEKNFE_01381 1.32e-290 - - - L - - - DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MFLEKNFE_01382 5.44e-56 - - - - - - - -
MFLEKNFE_01383 4.95e-44 - - - L - - - leucine-zipper of insertion element IS481
MFLEKNFE_01384 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MFLEKNFE_01385 1.36e-208 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MFLEKNFE_01386 5.06e-68 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MFLEKNFE_01387 2.91e-179 - - - S - - - NADPH-dependent FMN reductase
MFLEKNFE_01388 1.12e-243 - - - - - - - -
MFLEKNFE_01389 3.28e-278 yibE - - S - - - overlaps another CDS with the same product name
MFLEKNFE_01390 8.44e-163 yibF - - S - - - overlaps another CDS with the same product name
MFLEKNFE_01391 4.77e-130 - - - K - - - FR47-like protein
MFLEKNFE_01392 1.76e-155 gpm5 - - G - - - Phosphoglycerate mutase family
MFLEKNFE_01393 7.32e-247 - - - I - - - alpha/beta hydrolase fold
MFLEKNFE_01394 0.0 xylP2 - - G - - - symporter
MFLEKNFE_01395 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MFLEKNFE_01396 1.2e-281 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
MFLEKNFE_01397 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MFLEKNFE_01398 2.41e-66 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
MFLEKNFE_01399 4.09e-155 azlC - - E - - - branched-chain amino acid
MFLEKNFE_01400 1.75e-47 - - - K - - - MerR HTH family regulatory protein
MFLEKNFE_01401 8.41e-170 - - - - - - - -
MFLEKNFE_01402 2.72e-152 - - - S - - - Domain of unknown function (DUF4811)
MFLEKNFE_01403 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MFLEKNFE_01404 7.79e-112 - - - K - - - MerR HTH family regulatory protein
MFLEKNFE_01405 1.36e-77 - - - - - - - -
MFLEKNFE_01406 2.94e-155 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
MFLEKNFE_01407 1.78e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MFLEKNFE_01408 9.29e-169 - - - S - - - Putative threonine/serine exporter
MFLEKNFE_01409 7.76e-100 - - - S - - - Threonine/Serine exporter, ThrE
MFLEKNFE_01410 2.34e-242 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MFLEKNFE_01411 2.05e-153 - - - I - - - phosphatase
MFLEKNFE_01412 3.88e-198 - - - I - - - alpha/beta hydrolase fold
MFLEKNFE_01413 3.03e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MFLEKNFE_01414 1.7e-118 - - - K - - - Transcriptional regulator
MFLEKNFE_01415 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MFLEKNFE_01416 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
MFLEKNFE_01417 1.06e-152 dacB 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
MFLEKNFE_01418 1.11e-148 dgk2 - - F - - - deoxynucleoside kinase
MFLEKNFE_01419 3.27e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MFLEKNFE_01427 9.78e-102 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MFLEKNFE_01428 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MFLEKNFE_01429 1.16e-140 - - - K - - - Bacterial regulatory proteins, tetR family
MFLEKNFE_01430 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFLEKNFE_01431 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFLEKNFE_01432 8.58e-149 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
MFLEKNFE_01433 4.19e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MFLEKNFE_01434 1.19e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MFLEKNFE_01435 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MFLEKNFE_01436 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MFLEKNFE_01437 4.34e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MFLEKNFE_01438 1.15e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MFLEKNFE_01439 2.27e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MFLEKNFE_01440 6.61e-193 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MFLEKNFE_01441 1.85e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MFLEKNFE_01442 3.59e-69 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MFLEKNFE_01443 5.46e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MFLEKNFE_01444 8.29e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MFLEKNFE_01445 1.11e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MFLEKNFE_01446 1.96e-54 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MFLEKNFE_01447 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MFLEKNFE_01448 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MFLEKNFE_01449 3.53e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MFLEKNFE_01450 4.99e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MFLEKNFE_01451 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MFLEKNFE_01452 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MFLEKNFE_01453 5.32e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MFLEKNFE_01454 8.44e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MFLEKNFE_01455 1.32e-91 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MFLEKNFE_01456 5.95e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MFLEKNFE_01457 1.84e-160 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MFLEKNFE_01458 1.19e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MFLEKNFE_01459 9.65e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MFLEKNFE_01460 7.71e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MFLEKNFE_01461 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFLEKNFE_01462 7.76e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MFLEKNFE_01463 1.02e-233 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MFLEKNFE_01464 1.41e-122 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
MFLEKNFE_01465 5.37e-112 - - - S - - - NusG domain II
MFLEKNFE_01466 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MFLEKNFE_01467 6.44e-194 - - - S - - - FMN_bind
MFLEKNFE_01468 1.07e-264 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MFLEKNFE_01469 1.98e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFLEKNFE_01470 1.16e-210 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFLEKNFE_01471 9.72e-184 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFLEKNFE_01472 3.06e-194 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MFLEKNFE_01473 4.58e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MFLEKNFE_01474 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MFLEKNFE_01475 2.44e-209 yitS - - S - - - Uncharacterised protein, DegV family COG1307
MFLEKNFE_01476 1e-234 - - - S - - - Membrane
MFLEKNFE_01477 1.51e-258 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
MFLEKNFE_01478 0.0 tkt2 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MFLEKNFE_01479 2.35e-211 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MFLEKNFE_01480 3.3e-235 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 DAHP synthetase I family
MFLEKNFE_01481 1.23e-251 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MFLEKNFE_01482 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MFLEKNFE_01483 1.51e-69 yitW - - S - - - Iron-sulfur cluster assembly protein
MFLEKNFE_01484 2.01e-147 - 4.2.1.2, 4.2.1.32 - C ko:K01676,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
MFLEKNFE_01485 3.01e-225 ttdA 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
MFLEKNFE_01486 6.33e-254 - - - K - - - Helix-turn-helix domain
MFLEKNFE_01487 9.07e-196 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MFLEKNFE_01488 2.04e-170 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MFLEKNFE_01489 3.54e-180 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MFLEKNFE_01490 3e-222 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MFLEKNFE_01491 1.18e-66 - - - - - - - -
MFLEKNFE_01492 9.2e-215 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MFLEKNFE_01493 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MFLEKNFE_01494 8.69e-230 citR - - K - - - sugar-binding domain protein
MFLEKNFE_01495 5.51e-264 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
MFLEKNFE_01496 2.52e-240 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MFLEKNFE_01497 1.23e-58 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
MFLEKNFE_01498 3.32e-210 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
MFLEKNFE_01499 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
MFLEKNFE_01501 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MFLEKNFE_01502 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MFLEKNFE_01503 1.98e-122 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MFLEKNFE_01504 4.35e-205 mleR2 - - K - - - LysR family transcriptional regulator
MFLEKNFE_01505 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MFLEKNFE_01506 2.27e-82 - - - P - - - Rhodanese Homology Domain
MFLEKNFE_01507 7.43e-119 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFLEKNFE_01508 1.93e-266 - - - - - - - -
MFLEKNFE_01509 7.4e-278 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
MFLEKNFE_01510 6.75e-206 - - - C - - - Zinc-binding dehydrogenase
MFLEKNFE_01511 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
MFLEKNFE_01512 1.27e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MFLEKNFE_01513 2.66e-306 - - - U ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
MFLEKNFE_01514 4.38e-102 - - - K - - - Transcriptional regulator
MFLEKNFE_01515 7.87e-266 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MFLEKNFE_01516 0.0 nox - - P - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MFLEKNFE_01517 1.68e-176 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MFLEKNFE_01518 1.25e-140 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MFLEKNFE_01519 2.65e-93 spx2 - - P ko:K16509 - ko00000 ArsC family
MFLEKNFE_01520 1.56e-90 - - - S - - - Protein of unknown function (DUF1722)
MFLEKNFE_01521 4.88e-147 - - - GM - - - epimerase
MFLEKNFE_01522 0.0 - - - S - - - Zinc finger, swim domain protein
MFLEKNFE_01523 5.04e-155 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
MFLEKNFE_01524 2.31e-132 thgA3 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
MFLEKNFE_01525 2.49e-167 - - - K - - - Helix-turn-helix domain, rpiR family
MFLEKNFE_01526 6.46e-207 - - - S - - - Alpha beta hydrolase
MFLEKNFE_01527 5.89e-145 - - - GM - - - NmrA-like family
MFLEKNFE_01528 9.69e-99 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2255)
MFLEKNFE_01529 3.86e-205 - - - K - - - Transcriptional regulator
MFLEKNFE_01530 1.04e-218 cryZ 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
MFLEKNFE_01531 1.58e-21 - - - S - - - Alpha beta hydrolase
MFLEKNFE_01532 0.0 nox4 - - C - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MFLEKNFE_01533 9.11e-134 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
MFLEKNFE_01534 7.78e-261 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFLEKNFE_01535 7.05e-172 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MFLEKNFE_01536 4.87e-203 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MFLEKNFE_01538 6.64e-109 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MFLEKNFE_01539 4.54e-93 - - - K - - - MarR family
MFLEKNFE_01540 4.27e-147 - - - S - - - Psort location CytoplasmicMembrane, score
MFLEKNFE_01541 4.36e-208 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_01542 2.11e-170 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MFLEKNFE_01543 5.21e-254 - - - - - - - -
MFLEKNFE_01544 2.59e-256 - - - - - - - -
MFLEKNFE_01545 2.45e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_01546 6.86e-85 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MFLEKNFE_01547 1.74e-251 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MFLEKNFE_01548 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MFLEKNFE_01549 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MFLEKNFE_01550 8.64e-224 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MFLEKNFE_01551 2.84e-189 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MFLEKNFE_01552 4.58e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MFLEKNFE_01553 1.15e-94 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MFLEKNFE_01554 7.7e-110 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MFLEKNFE_01555 4.81e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MFLEKNFE_01556 9.21e-94 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
MFLEKNFE_01557 1.09e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MFLEKNFE_01558 2.32e-194 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MFLEKNFE_01559 3.65e-166 - - - C - - - Enoyl-(Acyl carrier protein) reductase
MFLEKNFE_01560 7.36e-220 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MFLEKNFE_01561 5.49e-286 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MFLEKNFE_01562 4.35e-204 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MFLEKNFE_01563 2.61e-132 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MFLEKNFE_01564 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MFLEKNFE_01565 2.47e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MFLEKNFE_01566 2.83e-200 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
MFLEKNFE_01567 3.23e-214 - - - G - - - Fructosamine kinase
MFLEKNFE_01568 5.97e-151 yjcF - - J - - - HAD-hyrolase-like
MFLEKNFE_01569 8.2e-102 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MFLEKNFE_01570 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MFLEKNFE_01571 2.56e-76 - - - - - - - -
MFLEKNFE_01572 3.13e-172 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MFLEKNFE_01573 2.04e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MFLEKNFE_01574 1.11e-147 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MFLEKNFE_01575 4.78e-65 - - - - - - - -
MFLEKNFE_01576 1.73e-67 - - - - - - - -
MFLEKNFE_01577 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MFLEKNFE_01578 1.68e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MFLEKNFE_01579 5.75e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFLEKNFE_01580 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MFLEKNFE_01581 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFLEKNFE_01582 8.59e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
MFLEKNFE_01583 8.49e-266 pbpX2 - - V - - - Beta-lactamase
MFLEKNFE_01584 2.54e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MFLEKNFE_01585 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MFLEKNFE_01586 4.94e-115 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MFLEKNFE_01587 4.42e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MFLEKNFE_01588 1.19e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MFLEKNFE_01589 7.56e-242 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MFLEKNFE_01590 6.29e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MFLEKNFE_01591 1.45e-114 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MFLEKNFE_01592 8.88e-248 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
MFLEKNFE_01593 8.18e-303 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MFLEKNFE_01594 1.63e-121 - - - - - - - -
MFLEKNFE_01595 9.01e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MFLEKNFE_01596 0.0 - - - G - - - Major Facilitator
MFLEKNFE_01597 3.04e-71 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MFLEKNFE_01598 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MFLEKNFE_01599 5.46e-62 ylxQ - - J - - - ribosomal protein
MFLEKNFE_01600 2.95e-65 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MFLEKNFE_01601 4.46e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MFLEKNFE_01602 9.74e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MFLEKNFE_01603 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MFLEKNFE_01604 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MFLEKNFE_01605 4.64e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MFLEKNFE_01606 1.13e-175 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MFLEKNFE_01607 3.17e-190 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MFLEKNFE_01608 9.83e-113 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MFLEKNFE_01609 3.01e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MFLEKNFE_01610 1.88e-194 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MFLEKNFE_01611 6.33e-185 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MFLEKNFE_01612 2.92e-172 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
MFLEKNFE_01613 1.92e-239 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFLEKNFE_01614 1.02e-66 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
MFLEKNFE_01615 1.14e-175 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MFLEKNFE_01616 8.8e-155 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MFLEKNFE_01617 3.96e-44 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
MFLEKNFE_01618 7.68e-48 ynzC - - S - - - UPF0291 protein
MFLEKNFE_01619 7.22e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MFLEKNFE_01620 7.8e-123 - - - - - - - -
MFLEKNFE_01621 6.35e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MFLEKNFE_01622 5.82e-100 - - - - - - - -
MFLEKNFE_01623 3.81e-87 - - - - - - - -
MFLEKNFE_01624 2.3e-226 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase like family 2
MFLEKNFE_01625 8.9e-131 - - - L - - - Helix-turn-helix domain
MFLEKNFE_01626 1.89e-282 ywtF_2 - - K - - - Cell envelope-related transcriptional attenuator domain
MFLEKNFE_01627 3.82e-184 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MFLEKNFE_01628 0.0 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFLEKNFE_01629 2.38e-294 rodA - - D ko:K05837 - ko00000,ko03036 Cell cycle protein
MFLEKNFE_01631 2.04e-20 - 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Hydrolase, nudix family
MFLEKNFE_01632 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MFLEKNFE_01633 5.33e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MFLEKNFE_01634 1.93e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MFLEKNFE_01635 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MFLEKNFE_01636 4.3e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MFLEKNFE_01637 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MFLEKNFE_01638 1.07e-103 yabR - - J ko:K07571 - ko00000 RNA binding
MFLEKNFE_01639 2.02e-83 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MFLEKNFE_01641 7.72e-57 yabO - - J - - - S4 domain protein
MFLEKNFE_01642 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MFLEKNFE_01643 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MFLEKNFE_01644 1.43e-129 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MFLEKNFE_01645 2.79e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MFLEKNFE_01646 0.0 - - - S - - - Putative peptidoglycan binding domain
MFLEKNFE_01647 4.87e-148 - - - S - - - (CBS) domain
MFLEKNFE_01648 8.1e-157 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MFLEKNFE_01649 5.29e-211 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MFLEKNFE_01650 5.3e-110 queT - - S - - - QueT transporter
MFLEKNFE_01651 2.16e-240 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MFLEKNFE_01652 1.9e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
MFLEKNFE_01653 2.36e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MFLEKNFE_01654 1.38e-293 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MFLEKNFE_01655 6.25e-245 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MFLEKNFE_01656 3.7e-260 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MFLEKNFE_01657 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MFLEKNFE_01658 8.22e-171 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MFLEKNFE_01659 1.06e-202 - - - U ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MFLEKNFE_01660 1.37e-248 - - - P ko:K02051 - ko00000,ko00002,ko02000 ABC transporter, substratebinding protein
MFLEKNFE_01661 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MFLEKNFE_01662 2.58e-85 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MFLEKNFE_01663 5e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MFLEKNFE_01664 9.32e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MFLEKNFE_01665 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MFLEKNFE_01666 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MFLEKNFE_01667 1.84e-189 - - - - - - - -
MFLEKNFE_01668 4.58e-194 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MFLEKNFE_01669 5.35e-121 lemA - - S ko:K03744 - ko00000 LemA family
MFLEKNFE_01670 3.14e-164 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
MFLEKNFE_01671 1.05e-273 - - - J - - - translation release factor activity
MFLEKNFE_01672 1.91e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MFLEKNFE_01673 6.26e-306 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MFLEKNFE_01674 2.08e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MFLEKNFE_01675 4.01e-36 - - - - - - - -
MFLEKNFE_01676 6.59e-170 - - - S - - - YheO-like PAS domain
MFLEKNFE_01677 2.81e-202 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MFLEKNFE_01678 1.52e-158 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
MFLEKNFE_01679 1.32e-289 sdaC - - E ko:K03837 - ko00000,ko02000 amino acid
MFLEKNFE_01680 2.66e-308 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MFLEKNFE_01681 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MFLEKNFE_01682 2.96e-89 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MFLEKNFE_01683 2.87e-101 ywiB - - S - - - Domain of unknown function (DUF1934)
MFLEKNFE_01684 8.97e-200 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
MFLEKNFE_01685 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
MFLEKNFE_01686 4.15e-191 yxeH - - S - - - hydrolase
MFLEKNFE_01687 7.12e-178 - - - - - - - -
MFLEKNFE_01688 1.15e-235 - - - S - - - DUF218 domain
MFLEKNFE_01689 3.26e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MFLEKNFE_01690 1.1e-193 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MFLEKNFE_01691 3.28e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MFLEKNFE_01692 1.96e-189 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MFLEKNFE_01693 5.3e-49 - - - - - - - -
MFLEKNFE_01694 2.4e-56 - - - S - - - ankyrin repeats
MFLEKNFE_01695 6.39e-169 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MFLEKNFE_01696 8.05e-166 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MFLEKNFE_01697 1.56e-229 - - - S ko:K06889 - ko00000 Prolyl oligopeptidase family
MFLEKNFE_01698 1.86e-208 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MFLEKNFE_01699 6.87e-50 veg - - S - - - Biofilm formation stimulator VEG
MFLEKNFE_01700 2.5e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MFLEKNFE_01701 3.1e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MFLEKNFE_01702 1.63e-187 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MFLEKNFE_01703 4.08e-270 - - - EGP ko:K02030 - ko00000,ko00002,ko02000 Drug resistance transporter Bcr CflA subfamily
MFLEKNFE_01704 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MFLEKNFE_01705 1.22e-37 - - - F - - - DNA mismatch repair protein MutT
MFLEKNFE_01706 1.12e-205 yunF - - F - - - Protein of unknown function DUF72
MFLEKNFE_01707 8.73e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
MFLEKNFE_01708 4.65e-229 - - - - - - - -
MFLEKNFE_01709 2.28e-289 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MFLEKNFE_01710 1.36e-214 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MFLEKNFE_01711 5.08e-194 - - - S - - - Psort location Cytoplasmic, score
MFLEKNFE_01712 1.23e-262 - - - - - - - -
MFLEKNFE_01713 2.94e-244 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MFLEKNFE_01714 9.75e-175 yecA - - K - - - Helix-turn-helix domain, rpiR family
MFLEKNFE_01715 6.97e-209 - - - GK - - - ROK family
MFLEKNFE_01716 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MFLEKNFE_01717 0.0 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFLEKNFE_01718 3.55e-99 - - - S - - - Domain of unknown function (DUF3284)
MFLEKNFE_01719 9.68e-34 - - - - - - - -
MFLEKNFE_01720 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFLEKNFE_01721 2.69e-166 - - - K - - - UbiC transcription regulator-associated domain protein
MFLEKNFE_01722 8.19e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MFLEKNFE_01723 1.38e-179 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
MFLEKNFE_01724 0.0 - - - L - - - DNA helicase
MFLEKNFE_01725 1.85e-40 - - - - - - - -
MFLEKNFE_01726 3.34e-147 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MFLEKNFE_01727 2.75e-145 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
MFLEKNFE_01728 5.04e-155 plnU - - S ko:K07052 - ko00000 CAAX protease self-immunity
MFLEKNFE_01729 3.26e-124 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MFLEKNFE_01730 1.49e-309 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
MFLEKNFE_01731 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MFLEKNFE_01732 8.82e-32 - - - - - - - -
MFLEKNFE_01733 1.93e-31 plnF - - - - - - -
MFLEKNFE_01734 2.34e-166 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MFLEKNFE_01735 1.05e-173 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MFLEKNFE_01736 2.48e-172 sppR - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MFLEKNFE_01737 2.08e-301 plnB 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MFLEKNFE_01738 1.9e-25 plnA - - - - - - -
MFLEKNFE_01739 1.22e-36 - - - - - - - -
MFLEKNFE_01740 2.08e-160 plnP - - S - - - CAAX protease self-immunity
MFLEKNFE_01741 4.33e-204 - - - M - - - Glycosyl transferase family 2
MFLEKNFE_01742 9.79e-191 - 3.1.3.23 - S ko:K07757 - ko00000,ko01000 Sucrose-6F-phosphate phosphohydrolase
MFLEKNFE_01743 3.15e-158 - - - T - - - EAL domain
MFLEKNFE_01744 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MFLEKNFE_01745 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MFLEKNFE_01746 2.18e-182 ybbR - - S - - - YbbR-like protein
MFLEKNFE_01747 8.33e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MFLEKNFE_01748 5.68e-156 - - - S - - - Protein of unknown function (DUF1361)
MFLEKNFE_01749 3.07e-119 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFLEKNFE_01750 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
MFLEKNFE_01751 6.24e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MFLEKNFE_01752 1.71e-210 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
MFLEKNFE_01753 1.03e-197 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MFLEKNFE_01754 2.41e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MFLEKNFE_01755 2.52e-114 - - - J - - - Acetyltransferase (GNAT) domain
MFLEKNFE_01756 1.29e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MFLEKNFE_01757 1.23e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MFLEKNFE_01758 1.4e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MFLEKNFE_01759 1.98e-199 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
MFLEKNFE_01760 6.57e-136 - - - - - - - -
MFLEKNFE_01761 9.36e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_01762 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFLEKNFE_01763 0.0 - - - M - - - Domain of unknown function (DUF5011)
MFLEKNFE_01764 2.4e-107 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MFLEKNFE_01765 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MFLEKNFE_01766 6.62e-180 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
MFLEKNFE_01767 1.76e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MFLEKNFE_01768 0.0 eriC - - P ko:K03281 - ko00000 chloride
MFLEKNFE_01769 5.11e-171 - - - - - - - -
MFLEKNFE_01770 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MFLEKNFE_01771 7.15e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MFLEKNFE_01772 1.31e-285 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MFLEKNFE_01773 2.02e-245 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MFLEKNFE_01774 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
MFLEKNFE_01775 2.62e-269 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
MFLEKNFE_01777 5.11e-133 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MFLEKNFE_01778 6.3e-225 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFLEKNFE_01779 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFLEKNFE_01780 7e-215 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MFLEKNFE_01781 4.56e-243 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MFLEKNFE_01782 1.71e-207 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MFLEKNFE_01783 6.07e-114 - - - S - - - Short repeat of unknown function (DUF308)
MFLEKNFE_01784 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MFLEKNFE_01785 7.5e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MFLEKNFE_01786 2.21e-113 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MFLEKNFE_01787 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MFLEKNFE_01788 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MFLEKNFE_01789 9.45e-152 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
MFLEKNFE_01790 5.79e-253 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
MFLEKNFE_01791 1.89e-134 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MFLEKNFE_01792 0.0 nox2 - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MFLEKNFE_01793 5.9e-170 - - - T - - - Putative diguanylate phosphodiesterase
MFLEKNFE_01794 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MFLEKNFE_01795 7.54e-99 - - - S - - - Protein of unknown function (DUF3290)
MFLEKNFE_01796 4.31e-141 yviA - - S - - - Protein of unknown function (DUF421)
MFLEKNFE_01797 8.65e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MFLEKNFE_01798 7.91e-172 - - - T - - - diguanylate cyclase activity
MFLEKNFE_01799 0.0 - - - S - - - Bacterial cellulose synthase subunit
MFLEKNFE_01800 2.74e-277 ydaM - - M - - - Glycosyl transferase family group 2
MFLEKNFE_01801 8.36e-257 - - - S - - - Protein conserved in bacteria
MFLEKNFE_01802 2.45e-310 - - - - - - - -
MFLEKNFE_01803 3.69e-206 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
MFLEKNFE_01804 0.0 nox - - C - - - NADH oxidase
MFLEKNFE_01805 6.37e-160 - - - T - - - Putative diguanylate phosphodiesterase
MFLEKNFE_01806 1.13e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MFLEKNFE_01807 1.15e-234 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MFLEKNFE_01808 1.04e-211 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MFLEKNFE_01809 2.55e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MFLEKNFE_01810 2.87e-71 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
MFLEKNFE_01811 2.78e-65 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
MFLEKNFE_01812 1.55e-150 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MFLEKNFE_01813 2.31e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MFLEKNFE_01814 9.78e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MFLEKNFE_01815 5.04e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MFLEKNFE_01816 2.22e-206 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MFLEKNFE_01817 6.91e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MFLEKNFE_01818 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFLEKNFE_01819 1.49e-170 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MFLEKNFE_01820 1.28e-276 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
MFLEKNFE_01821 1.69e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MFLEKNFE_01822 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MFLEKNFE_01823 1.27e-129 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MFLEKNFE_01824 2.94e-164 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MFLEKNFE_01825 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MFLEKNFE_01826 3.7e-149 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MFLEKNFE_01827 6.57e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MFLEKNFE_01828 7.29e-247 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
MFLEKNFE_01829 0.0 ydaO - - E - - - amino acid
MFLEKNFE_01830 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MFLEKNFE_01831 9.82e-55 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MFLEKNFE_01832 1.68e-140 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
MFLEKNFE_01833 3.67e-154 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MFLEKNFE_01834 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MFLEKNFE_01835 7.63e-251 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MFLEKNFE_01836 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MFLEKNFE_01837 4.66e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
MFLEKNFE_01838 6.84e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MFLEKNFE_01839 2.84e-241 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
MFLEKNFE_01840 9.33e-177 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MFLEKNFE_01841 2.65e-177 phnE2 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter permease
MFLEKNFE_01842 3.33e-184 phnE1 - - U ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFLEKNFE_01843 1.52e-91 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
MFLEKNFE_01844 1.56e-125 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MFLEKNFE_01845 1.46e-60 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MFLEKNFE_01846 1.05e-179 - - - K - - - DeoR C terminal sensor domain
MFLEKNFE_01847 8.35e-230 rhaR - - K - - - helix_turn_helix, arabinose operon control protein
MFLEKNFE_01848 4.67e-314 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
MFLEKNFE_01849 0.0 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MFLEKNFE_01850 4.22e-74 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
MFLEKNFE_01851 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
MFLEKNFE_01852 6.23e-209 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
MFLEKNFE_01853 1.45e-162 - - - S - - - Membrane
MFLEKNFE_01854 4.04e-94 yueI - - S - - - Protein of unknown function (DUF1694)
MFLEKNFE_01855 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MFLEKNFE_01856 5.03e-95 - - - K - - - Transcriptional regulator
MFLEKNFE_01857 0.0 pox4 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MFLEKNFE_01858 1.97e-256 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MFLEKNFE_01860 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
MFLEKNFE_01861 6.12e-85 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
MFLEKNFE_01862 9.62e-19 - - - - - - - -
MFLEKNFE_01863 3.78e-212 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MFLEKNFE_01864 4.29e-173 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MFLEKNFE_01865 5.38e-101 nrp - - K ko:K16509 - ko00000 ArsC family
MFLEKNFE_01866 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family
MFLEKNFE_01867 1.96e-21 ytgB - - S - - - Transglycosylase associated protein
MFLEKNFE_01868 1.06e-16 - - - - - - - -
MFLEKNFE_01869 1.22e-115 - - - T - - - ECF transporter, substrate-specific component
MFLEKNFE_01870 2.43e-91 - - - S - - - Pyrimidine dimer DNA glycosylase
MFLEKNFE_01871 2.28e-291 - - - S - - - Pyridine nucleotide-disulphide oxidoreductase
MFLEKNFE_01872 3.53e-158 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MFLEKNFE_01873 1.86e-210 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MFLEKNFE_01874 2.93e-200 nanK - - GK - - - ROK family
MFLEKNFE_01875 3.83e-174 - - - G - - - Xylose isomerase domain protein TIM barrel
MFLEKNFE_01876 4.01e-263 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MFLEKNFE_01877 0.0 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFLEKNFE_01878 1.65e-206 - - - I - - - alpha/beta hydrolase fold
MFLEKNFE_01879 2.54e-210 - - - I - - - alpha/beta hydrolase fold
MFLEKNFE_01880 6.47e-95 - - - S - - - Protein of unknown function (DUF1694)
MFLEKNFE_01881 3.76e-180 - - - K - - - Helix-turn-helix domain, rpiR family
MFLEKNFE_01882 1.2e-262 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
MFLEKNFE_01883 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MFLEKNFE_01884 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
MFLEKNFE_01885 3.55e-174 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MFLEKNFE_01886 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
MFLEKNFE_01887 6.83e-133 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
MFLEKNFE_01888 4.84e-14 yueI - - S - - - Protein of unknown function (DUF1694)
MFLEKNFE_01889 4.44e-66 yueI - - S - - - Protein of unknown function (DUF1694)
MFLEKNFE_01890 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MFLEKNFE_01891 2.92e-159 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
MFLEKNFE_01892 3.99e-106 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MFLEKNFE_01893 6e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MFLEKNFE_01894 3.41e-295 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MFLEKNFE_01895 1.24e-245 - 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
MFLEKNFE_01896 4.53e-146 gph3 - - S - - - Haloacid dehalogenase-like hydrolase
MFLEKNFE_01897 0.0 - - - G ko:K03483 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MFLEKNFE_01898 1.58e-101 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MFLEKNFE_01899 2.97e-60 ulaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system galactitol-specific IIB component
MFLEKNFE_01900 1.43e-306 ulaA - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MFLEKNFE_01901 8.34e-147 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MFLEKNFE_01902 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MFLEKNFE_01903 9e-187 yxeH - - S - - - hydrolase
MFLEKNFE_01904 1.15e-236 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MFLEKNFE_01906 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
MFLEKNFE_01907 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MFLEKNFE_01908 2.66e-222 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
MFLEKNFE_01909 0.0 treP 2.4.1.64 GH65 G ko:K05342 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MFLEKNFE_01910 1.3e-203 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MFLEKNFE_01911 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFLEKNFE_01912 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MFLEKNFE_01913 0.0 pbg9 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MFLEKNFE_01914 3.72e-200 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MFLEKNFE_01915 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFLEKNFE_01916 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MFLEKNFE_01917 1.94e-270 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MFLEKNFE_01918 1.58e-207 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
MFLEKNFE_01919 3.06e-212 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MFLEKNFE_01920 1.21e-315 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFLEKNFE_01921 9.03e-173 - - - K - - - UTRA domain
MFLEKNFE_01922 2.63e-200 estA - - S - - - Putative esterase
MFLEKNFE_01923 2.09e-83 - - - - - - - -
MFLEKNFE_01924 1.12e-262 - - - EGP - - - Major Facilitator Superfamily
MFLEKNFE_01925 1.73e-215 - - - K - - - Transcriptional regulator, LysR family
MFLEKNFE_01926 5.56e-212 - - - G - - - Xylose isomerase-like TIM barrel
MFLEKNFE_01927 1.64e-202 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MFLEKNFE_01928 3.31e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MFLEKNFE_01929 1.15e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MFLEKNFE_01930 1.4e-282 - - - EGP - - - Major Facilitator Superfamily
MFLEKNFE_01931 4.62e-224 - - - K - - - Transcriptional regulator, LysR family
MFLEKNFE_01932 7.89e-213 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MFLEKNFE_01933 3.65e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MFLEKNFE_01934 1.23e-228 apbE3 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MFLEKNFE_01935 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MFLEKNFE_01936 2.02e-85 - - - S - - - pyridoxamine 5-phosphate
MFLEKNFE_01937 2.45e-246 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
MFLEKNFE_01938 3.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MFLEKNFE_01939 1.43e-251 galM3 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MFLEKNFE_01940 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MFLEKNFE_01941 4.22e-136 - - - K - - - Bacterial regulatory proteins, tetR family
MFLEKNFE_01942 1.7e-262 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MFLEKNFE_01943 3.38e-70 - - - - - - - -
MFLEKNFE_01944 2.49e-95 - - - - - - - -
MFLEKNFE_01945 2.87e-168 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MFLEKNFE_01946 7.34e-180 - - - EGP - - - Transmembrane secretion effector
MFLEKNFE_01947 1.15e-41 - - - G ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
MFLEKNFE_01948 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MFLEKNFE_01949 4.13e-182 - - - - - - - -
MFLEKNFE_01951 5.45e-94 spx1 - - P ko:K16509 - ko00000 ArsC family
MFLEKNFE_01952 3.88e-46 - - - - - - - -
MFLEKNFE_01953 2.08e-117 - - - V - - - VanZ like family
MFLEKNFE_01954 1.06e-314 - - - EGP - - - Major Facilitator
MFLEKNFE_01955 4.45e-226 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MFLEKNFE_01956 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MFLEKNFE_01957 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MFLEKNFE_01958 6.68e-197 licD - - M ko:K07271 - ko00000,ko01000 LicD family
MFLEKNFE_01959 6.16e-107 - - - K - - - Transcriptional regulator
MFLEKNFE_01960 1.36e-27 - - - - - - - -
MFLEKNFE_01961 1.79e-287 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MFLEKNFE_01962 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MFLEKNFE_01963 5.47e-198 ribC1 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MFLEKNFE_01964 0.0 pox2 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MFLEKNFE_01965 1.06e-230 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MFLEKNFE_01966 1.23e-229 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MFLEKNFE_01967 0.0 oatA - - I - - - Acyltransferase
MFLEKNFE_01968 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MFLEKNFE_01969 1.89e-90 - - - O - - - OsmC-like protein
MFLEKNFE_01970 1.09e-60 - - - - - - - -
MFLEKNFE_01971 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
MFLEKNFE_01972 6.12e-115 - - - - - - - -
MFLEKNFE_01973 7.76e-193 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MFLEKNFE_01974 3.05e-95 - - - F - - - Nudix hydrolase
MFLEKNFE_01975 1.48e-27 - - - - - - - -
MFLEKNFE_01976 7.32e-136 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
MFLEKNFE_01977 2.02e-106 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MFLEKNFE_01978 8.84e-18 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
MFLEKNFE_01979 1.01e-188 - - - - - - - -
MFLEKNFE_01980 6.94e-146 gph1 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
MFLEKNFE_01981 1.86e-267 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MFLEKNFE_01982 5.1e-218 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFLEKNFE_01983 1.28e-54 - - - - - - - -
MFLEKNFE_01985 2.3e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_01986 3.39e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MFLEKNFE_01987 1.81e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFLEKNFE_01988 1.27e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFLEKNFE_01989 1e-107 - - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MFLEKNFE_01990 1.34e-197 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MFLEKNFE_01991 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MFLEKNFE_01992 1.24e-179 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
MFLEKNFE_01993 8.73e-315 steT - - E ko:K03294 - ko00000 amino acid
MFLEKNFE_01994 2.55e-95 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFLEKNFE_01995 8.87e-191 - - - S - - - Sulfite exporter TauE/SafE
MFLEKNFE_01996 3.08e-93 - - - K - - - MarR family
MFLEKNFE_01997 8.85e-267 - - - EGP - - - Major Facilitator Superfamily
MFLEKNFE_01998 2.93e-109 - - - S ko:K07090 - ko00000 membrane transporter protein
MFLEKNFE_01999 1.81e-128 - - - K - - - Bacterial regulatory proteins, tetR family
MFLEKNFE_02000 5.95e-300 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MFLEKNFE_02001 1.88e-101 rppH3 - - F - - - NUDIX domain
MFLEKNFE_02002 3.5e-64 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
MFLEKNFE_02003 1.61e-36 - - - - - - - -
MFLEKNFE_02004 2.23e-164 pgm3 - - G - - - Phosphoglycerate mutase family
MFLEKNFE_02005 2.07e-161 gpm2 - - G - - - Phosphoglycerate mutase family
MFLEKNFE_02006 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MFLEKNFE_02007 4.16e-227 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
MFLEKNFE_02008 2.84e-146 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
MFLEKNFE_02009 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MFLEKNFE_02010 3.59e-212 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
MFLEKNFE_02011 3.69e-230 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MFLEKNFE_02012 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MFLEKNFE_02014 3.56e-171 spoVK - - O ko:K06413 - ko00000 ATPase family associated with various cellular activities (AAA)
MFLEKNFE_02016 4.77e-48 - - - L - - - Helix-turn-helix domain
MFLEKNFE_02017 1.51e-22 - - - L ko:K07497 - ko00000 hmm pf00665
MFLEKNFE_02018 8.56e-38 - - - L ko:K07497 - ko00000 hmm pf00665
MFLEKNFE_02019 6.67e-30 - - - L ko:K07497 - ko00000 hmm pf00665
MFLEKNFE_02020 1.38e-75 - - - - - - - -
MFLEKNFE_02021 1.08e-71 - - - - - - - -
MFLEKNFE_02022 1.37e-83 - - - K - - - Helix-turn-helix domain
MFLEKNFE_02023 1.16e-142 XK27_07075 - - V ko:K07052 - ko00000 CAAX protease self-immunity
MFLEKNFE_02024 3.08e-74 - - - K - - - HxlR-like helix-turn-helix
MFLEKNFE_02025 1.92e-301 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
MFLEKNFE_02026 3.5e-299 - - - S - - - Cysteine-rich secretory protein family
MFLEKNFE_02027 3.61e-61 - - - S - - - MORN repeat
MFLEKNFE_02028 0.0 XK27_09800 - - I - - - Acyltransferase family
MFLEKNFE_02029 7.38e-50 ydaS - - S - - - Transglycosylase associated protein
MFLEKNFE_02030 1.95e-116 - - - - - - - -
MFLEKNFE_02031 5.74e-32 - - - - - - - -
MFLEKNFE_02032 1.1e-93 asp1 - - S - - - Asp23 family, cell envelope-related function
MFLEKNFE_02033 1.04e-94 asp2 - - S - - - Asp23 family, cell envelope-related function
MFLEKNFE_02034 1.59e-189 yisK 3.7.1.5, 4.1.1.68 - Q ko:K05921,ko:K16164 ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Fumarylacetoacetate (FAA) hydrolase family
MFLEKNFE_02035 1.22e-210 yjdB - - S - - - Domain of unknown function (DUF4767)
MFLEKNFE_02036 5.21e-62 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MFLEKNFE_02037 2.19e-131 - - - G - - - Glycogen debranching enzyme
MFLEKNFE_02038 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MFLEKNFE_02039 0.0 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MFLEKNFE_02040 3.37e-60 - - - S - - - MazG-like family
MFLEKNFE_02041 2.31e-117 XK27_09665 - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
MFLEKNFE_02042 1.09e-164 - - - M - - - MucBP domain
MFLEKNFE_02043 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MFLEKNFE_02044 1.56e-46 ykuJ - - S - - - Protein of unknown function (DUF1797)
MFLEKNFE_02045 1.22e-292 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MFLEKNFE_02046 2.29e-292 dacA2 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MFLEKNFE_02047 2.16e-241 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MFLEKNFE_02048 2.04e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MFLEKNFE_02049 1.41e-285 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MFLEKNFE_02050 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MFLEKNFE_02051 1.24e-52 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MFLEKNFE_02052 5.6e-41 - - - - - - - -
MFLEKNFE_02053 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
MFLEKNFE_02054 2.5e-132 - - - L - - - Integrase
MFLEKNFE_02055 3.4e-85 - - - K - - - Winged helix DNA-binding domain
MFLEKNFE_02056 5.67e-231 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MFLEKNFE_02057 4.86e-258 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MFLEKNFE_02058 3.59e-241 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFLEKNFE_02059 3.44e-210 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFLEKNFE_02060 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MFLEKNFE_02061 3.85e-76 ywjH - - S - - - Protein of unknown function (DUF1634)
MFLEKNFE_02062 1.01e-172 - - - S ko:K07090 - ko00000 membrane transporter protein
MFLEKNFE_02063 1.36e-208 lysR5 - - K - - - LysR substrate binding domain
MFLEKNFE_02064 1.49e-252 - - - M - - - MucBP domain
MFLEKNFE_02065 0.0 - - - - - - - -
MFLEKNFE_02066 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MFLEKNFE_02067 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MFLEKNFE_02068 1.22e-218 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
MFLEKNFE_02069 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MFLEKNFE_02070 7.89e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
MFLEKNFE_02071 6.04e-94 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
MFLEKNFE_02072 1.13e-257 yueF - - S - - - AI-2E family transporter
MFLEKNFE_02073 4.22e-215 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MFLEKNFE_02074 7.98e-166 pbpX - - V - - - Beta-lactamase
MFLEKNFE_02075 7.17e-39 - - - S - - - Antitoxin component of a toxin-antitoxin (TA) module
MFLEKNFE_02076 5.64e-64 - - - K - - - sequence-specific DNA binding
MFLEKNFE_02077 9.64e-171 lytE - - M - - - NlpC/P60 family
MFLEKNFE_02078 6.62e-138 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MFLEKNFE_02079 8.27e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MFLEKNFE_02080 7.74e-168 - - - - - - - -
MFLEKNFE_02081 6.87e-131 - - - K - - - DNA-templated transcription, initiation
MFLEKNFE_02082 1.35e-34 - - - - - - - -
MFLEKNFE_02083 1.95e-41 - - - - - - - -
MFLEKNFE_02084 1.04e-45 - - - S - - - Protein of unknown function (DUF2922)
MFLEKNFE_02085 9.02e-70 - - - - - - - -
MFLEKNFE_02086 1.38e-155 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
MFLEKNFE_02087 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MFLEKNFE_02088 5.36e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFLEKNFE_02089 0.0 - - - M - - - domain protein
MFLEKNFE_02090 2.91e-176 - - - K - - - helix_turn_helix, arabinose operon control protein
MFLEKNFE_02091 8.42e-190 cps3J - - M - - - Domain of unknown function (DUF4422)
MFLEKNFE_02092 5.06e-260 cps3I - - G - - - Acyltransferase family
MFLEKNFE_02093 1.03e-264 cps3H - - - - - - -
MFLEKNFE_02094 1.73e-207 cps3F - - - - - - -
MFLEKNFE_02095 2.92e-145 cps3E - - - - - - -
MFLEKNFE_02096 1.6e-259 cps3D - - - - - - -
MFLEKNFE_02097 2.81e-282 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
MFLEKNFE_02098 3.01e-225 - - - S - - - Glycosyltransferase like family 2
MFLEKNFE_02099 1.54e-219 cps3A - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
MFLEKNFE_02100 7.72e-35 - - - S - - - Barstar (barnase inhibitor)
MFLEKNFE_02101 8.72e-73 - - - S - - - Immunity protein 63
MFLEKNFE_02103 2.32e-152 - - - - - - - -
MFLEKNFE_02105 2.87e-192 - - - L - - - Transposase and inactivated derivatives, IS30 family
MFLEKNFE_02106 0.000208 - - - U ko:K15125 ko05133,map05133 ko00000,ko00001,ko00536 Large exoproteins involved in heme utilization or adhesion
MFLEKNFE_02107 3.47e-142 - - - - - - - -
MFLEKNFE_02108 2.67e-173 - - - - - - - -
MFLEKNFE_02109 9.17e-41 - - - - - - - -
MFLEKNFE_02110 3.07e-48 - - - - - - - -
MFLEKNFE_02111 4.52e-153 - - - - - - - -
MFLEKNFE_02113 3.23e-58 - - - - - - - -
MFLEKNFE_02114 1.01e-172 - - - M ko:K21493 - ko00000,ko01000,ko02048 self proteolysis
MFLEKNFE_02115 3.59e-39 - - - M - - - domain protein
MFLEKNFE_02116 1.09e-138 - - - M - - - domain protein
MFLEKNFE_02117 1e-28 cps2K - - L ko:K07473 - ko00000,ko02048 bacterial-type proximal promoter sequence-specific DNA binding
MFLEKNFE_02118 2.34e-105 cps2J - - S - - - Polysaccharide biosynthesis protein
MFLEKNFE_02119 5.71e-57 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
MFLEKNFE_02120 2.08e-167 cps4I - - M - - - Glycosyltransferase like family 2
MFLEKNFE_02121 2.08e-218 - - - - - - - -
MFLEKNFE_02122 1.54e-159 cps4G - - M - - - Glycosyltransferase Family 4
MFLEKNFE_02123 1.47e-166 cps4F - - M - - - Glycosyl transferases group 1
MFLEKNFE_02124 8.38e-160 tuaA - - M - - - Bacterial sugar transferase
MFLEKNFE_02125 1.33e-226 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
MFLEKNFE_02126 1.69e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MFLEKNFE_02127 6.79e-163 ywqD - - D - - - Capsular exopolysaccharide family
MFLEKNFE_02128 1.79e-167 epsB - - M - - - biosynthesis protein
MFLEKNFE_02129 1.11e-84 - - - - - - - -
MFLEKNFE_02130 2e-98 yugI - - J ko:K07570,ko:K07571 - ko00000 general stress protein
MFLEKNFE_02131 5.16e-141 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MFLEKNFE_02132 7.18e-153 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
MFLEKNFE_02133 4.69e-151 - - - S - - - Protein of unknown function (DUF1461)
MFLEKNFE_02134 7.18e-189 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MFLEKNFE_02135 6.53e-115 yutD - - S - - - Protein of unknown function (DUF1027)
MFLEKNFE_02136 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MFLEKNFE_02137 5.77e-151 - - - S - - - Calcineurin-like phosphoesterase
MFLEKNFE_02138 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MFLEKNFE_02139 4.7e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MFLEKNFE_02140 1.56e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MFLEKNFE_02142 6.46e-113 - - - S - - - Prokaryotic N-terminal methylation motif
MFLEKNFE_02143 3.03e-27 - - - - ko:K02671 - ko00000,ko02035,ko02044 -
MFLEKNFE_02144 1.5e-108 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
MFLEKNFE_02145 1.97e-72 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
MFLEKNFE_02146 6.2e-242 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MFLEKNFE_02147 1.55e-225 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MFLEKNFE_02148 2.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MFLEKNFE_02149 2.21e-168 yebC - - K - - - Transcriptional regulatory protein
MFLEKNFE_02150 2.44e-65 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
MFLEKNFE_02151 7.88e-211 - - - G - - - Xylose isomerase domain protein TIM barrel
MFLEKNFE_02152 5.44e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MFLEKNFE_02153 1.55e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MFLEKNFE_02154 9.11e-106 - - - K - - - helix_turn_helix, mercury resistance
MFLEKNFE_02155 1.6e-96 - - - - - - - -
MFLEKNFE_02156 1.88e-75 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MFLEKNFE_02157 2.31e-202 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MFLEKNFE_02158 7.85e-288 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MFLEKNFE_02159 2.29e-112 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MFLEKNFE_02160 1.13e-113 ykuL - - S - - - (CBS) domain
MFLEKNFE_02161 4.53e-122 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MFLEKNFE_02162 8.49e-144 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MFLEKNFE_02163 5.06e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MFLEKNFE_02164 1.45e-161 yslB - - S - - - Protein of unknown function (DUF2507)
MFLEKNFE_02165 3e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MFLEKNFE_02166 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MFLEKNFE_02167 1.06e-49 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MFLEKNFE_02168 1.31e-63 yrzB - - S - - - Belongs to the UPF0473 family
MFLEKNFE_02169 5.39e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MFLEKNFE_02170 5e-57 yrzL - - S - - - Belongs to the UPF0297 family
MFLEKNFE_02171 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MFLEKNFE_02172 2.79e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MFLEKNFE_02173 8.32e-227 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MFLEKNFE_02174 2.48e-276 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MFLEKNFE_02175 1.32e-63 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MFLEKNFE_02176 9.91e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MFLEKNFE_02177 5.87e-256 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MFLEKNFE_02178 2.62e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MFLEKNFE_02179 2.83e-138 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MFLEKNFE_02180 2.07e-118 - - - - - - - -
MFLEKNFE_02181 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MFLEKNFE_02182 1.35e-93 - - - - - - - -
MFLEKNFE_02183 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MFLEKNFE_02184 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MFLEKNFE_02185 6.18e-197 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 YmdB-like protein
MFLEKNFE_02186 6.57e-291 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MFLEKNFE_02187 2.43e-264 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MFLEKNFE_02188 4.47e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MFLEKNFE_02189 1.92e-127 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MFLEKNFE_02190 5.74e-172 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
MFLEKNFE_02191 0.0 ymfH - - S - - - Peptidase M16
MFLEKNFE_02192 8.72e-297 ymfF - - S - - - Peptidase M16 inactive domain protein
MFLEKNFE_02193 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MFLEKNFE_02194 2.61e-199 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MFLEKNFE_02195 3.17e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_02196 1.89e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MFLEKNFE_02197 1.23e-187 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MFLEKNFE_02198 5.41e-150 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MFLEKNFE_02199 9.47e-115 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
MFLEKNFE_02200 3.76e-184 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MFLEKNFE_02201 1.74e-211 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MFLEKNFE_02202 1.15e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
MFLEKNFE_02203 9.36e-317 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MFLEKNFE_02204 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MFLEKNFE_02205 3.56e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MFLEKNFE_02206 4.5e-299 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
MFLEKNFE_02207 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFLEKNFE_02208 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_02209 3.72e-226 - - - O - - - protein import
MFLEKNFE_02210 1.67e-292 amd - - E - - - Peptidase family M20/M25/M40
MFLEKNFE_02211 2.43e-208 yhxD - - IQ - - - KR domain
MFLEKNFE_02213 9.01e-89 - - - - - - - -
MFLEKNFE_02214 3.51e-185 - - - K - - - Helix-turn-helix XRE-family like proteins
MFLEKNFE_02215 0.0 - - - E - - - Amino Acid
MFLEKNFE_02216 1.67e-86 lysM - - M - - - LysM domain
MFLEKNFE_02217 2.14e-190 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
MFLEKNFE_02218 0.0 copA 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MFLEKNFE_02219 1.23e-57 - - - S - - - Cupredoxin-like domain
MFLEKNFE_02220 1.36e-84 - - - S - - - Cupredoxin-like domain
MFLEKNFE_02221 0.0 aapA - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MFLEKNFE_02222 2.81e-181 - - - K - - - Helix-turn-helix domain
MFLEKNFE_02223 1.47e-51 - - - S ko:K07343 - ko00000 TfoX C-terminal domain
MFLEKNFE_02224 3.05e-289 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MFLEKNFE_02225 0.0 - - - - - - - -
MFLEKNFE_02226 2.69e-99 - - - - - - - -
MFLEKNFE_02227 4.72e-242 - - - S - - - Cell surface protein
MFLEKNFE_02228 6.02e-137 - - - S - - - WxL domain surface cell wall-binding
MFLEKNFE_02229 4.62e-226 - - - C - - - Alcohol dehydrogenase GroES-like domain
MFLEKNFE_02230 1.27e-90 - - - S - - - Iron-sulphur cluster biosynthesis
MFLEKNFE_02231 1.36e-148 - - - S - - - GyrI-like small molecule binding domain
MFLEKNFE_02232 1.52e-241 ynjC - - S - - - Cell surface protein
MFLEKNFE_02233 4.48e-130 - - - S - - - WxL domain surface cell wall-binding
MFLEKNFE_02234 1.47e-83 - - - - - - - -
MFLEKNFE_02235 6.11e-303 - - - NU - - - Mycoplasma protein of unknown function, DUF285
MFLEKNFE_02236 4.8e-156 - - - - - - - -
MFLEKNFE_02237 4.31e-149 - - - S - - - Haloacid dehalogenase-like hydrolase
MFLEKNFE_02238 3.25e-81 ytcD - - K - - - Transcriptional regulator, HxlR family
MFLEKNFE_02239 1.48e-271 - - - EGP - - - Major Facilitator
MFLEKNFE_02240 4.52e-147 - - - M - - - ErfK YbiS YcfS YnhG
MFLEKNFE_02241 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MFLEKNFE_02242 1.38e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MFLEKNFE_02243 1.77e-282 blpH 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MFLEKNFE_02244 1.59e-130 - - - K - - - Bacterial regulatory proteins, tetR family
MFLEKNFE_02245 2.65e-216 - - - GM - - - NmrA-like family
MFLEKNFE_02246 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MFLEKNFE_02247 0.0 - - - M - - - Glycosyl hydrolases family 25
MFLEKNFE_02248 1.62e-62 - - - S - - - Domain of unknown function (DUF1905)
MFLEKNFE_02249 1.27e-83 - - - K - - - HxlR-like helix-turn-helix
MFLEKNFE_02250 3.27e-170 - - - S - - - KR domain
MFLEKNFE_02251 2.46e-127 - - - K - - - Bacterial regulatory proteins, tetR family
MFLEKNFE_02252 3.47e-244 - 1.1.1.219 - GM ko:K00091 - ko00000,ko01000 Male sterility protein
MFLEKNFE_02253 1.09e-130 - - - S - - - Protein of unknown function (DUF1211)
MFLEKNFE_02254 1.97e-229 ydhF - - S - - - Aldo keto reductase
MFLEKNFE_02255 0.0 yfjF - - U - - - Sugar (and other) transporter
MFLEKNFE_02256 2.64e-141 - - - K - - - Bacterial regulatory proteins, tetR family
MFLEKNFE_02257 1.22e-219 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
MFLEKNFE_02258 2.13e-186 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MFLEKNFE_02259 5.2e-228 fhuB - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFLEKNFE_02260 8.17e-220 fhuG - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFLEKNFE_02261 3.74e-120 - - - K - - - Bacterial regulatory proteins, tetR family
MFLEKNFE_02262 6.73e-211 - - - GM - - - NmrA-like family
MFLEKNFE_02263 2.47e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLEKNFE_02264 1.4e-96 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MFLEKNFE_02265 6.38e-195 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
MFLEKNFE_02266 3.86e-85 - - - K - - - helix_turn_helix, mercury resistance
MFLEKNFE_02267 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MFLEKNFE_02268 2.22e-235 - - - S - - - Bacterial protein of unknown function (DUF916)
MFLEKNFE_02269 1.1e-115 - - - S - - - WxL domain surface cell wall-binding
MFLEKNFE_02270 1.09e-197 - - - NU - - - Mycoplasma protein of unknown function, DUF285
MFLEKNFE_02271 6.01e-220 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MFLEKNFE_02272 0.0 - 3.6.3.44 - P ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter transmembrane region
MFLEKNFE_02273 4.63e-24 - - - - - - - -
MFLEKNFE_02274 2.16e-26 - - - - - - - -
MFLEKNFE_02275 9.35e-24 - - - - - - - -
MFLEKNFE_02276 9.35e-24 - - - - - - - -
MFLEKNFE_02277 1.07e-26 - - - - - - - -
MFLEKNFE_02278 1.56e-22 - - - - - - - -
MFLEKNFE_02279 3.26e-24 - - - - - - - -
MFLEKNFE_02280 6.58e-24 - - - - - - - -
MFLEKNFE_02281 0.0 inlJ - - M - - - MucBP domain
MFLEKNFE_02282 0.0 - - - D - - - nuclear chromosome segregation
MFLEKNFE_02283 1.27e-109 - - - K - - - MarR family
MFLEKNFE_02284 5.38e-57 - - - - - - - -
MFLEKNFE_02285 1.28e-51 - - - - - - - -
MFLEKNFE_02287 1.98e-40 - - - - - - - -
MFLEKNFE_02290 2.96e-182 icaB - - G - - - Polysaccharide deacetylase
MFLEKNFE_02291 1.81e-85 yxeA - - S - - - Protein of unknown function (DUF1093)
MFLEKNFE_02292 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_02293 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
MFLEKNFE_02294 5.37e-182 - - - - - - - -
MFLEKNFE_02295 1.33e-77 - - - - - - - -
MFLEKNFE_02296 1.9e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MFLEKNFE_02297 8.57e-41 - - - - - - - -
MFLEKNFE_02298 1.12e-246 ampC - - V - - - Beta-lactamase
MFLEKNFE_02299 4.95e-250 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MFLEKNFE_02300 1.83e-175 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
MFLEKNFE_02301 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
MFLEKNFE_02302 1.54e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MFLEKNFE_02303 1.88e-251 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MFLEKNFE_02304 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MFLEKNFE_02305 4.39e-244 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MFLEKNFE_02306 3.04e-297 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MFLEKNFE_02307 7.81e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MFLEKNFE_02308 2.49e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MFLEKNFE_02309 4.82e-165 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MFLEKNFE_02310 1.81e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MFLEKNFE_02311 5.41e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MFLEKNFE_02312 2.03e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MFLEKNFE_02313 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MFLEKNFE_02314 9.14e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MFLEKNFE_02315 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MFLEKNFE_02316 5.95e-74 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MFLEKNFE_02317 2.94e-315 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MFLEKNFE_02318 1.68e-132 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MFLEKNFE_02319 1.44e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MFLEKNFE_02320 1.52e-57 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MFLEKNFE_02321 2.54e-46 - - - S - - - Protein of unknown function (DUF2969)
MFLEKNFE_02322 2.15e-280 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MFLEKNFE_02323 3.2e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
MFLEKNFE_02324 2.24e-239 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MFLEKNFE_02325 2.1e-151 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFLEKNFE_02326 1.23e-190 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MFLEKNFE_02327 3.34e-215 hicD3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MFLEKNFE_02328 1.88e-226 - - - S - - - Protein of unknown function (DUF2785)
MFLEKNFE_02329 7.55e-242 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MFLEKNFE_02330 6.54e-273 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MFLEKNFE_02331 0.0 glpQ3 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
MFLEKNFE_02332 4.7e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
MFLEKNFE_02333 1.91e-259 bla2 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MFLEKNFE_02334 2.37e-107 uspA - - T - - - universal stress protein
MFLEKNFE_02335 1.34e-52 - - - - - - - -
MFLEKNFE_02336 2.96e-302 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MFLEKNFE_02337 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
MFLEKNFE_02338 1.31e-119 - - - K - - - Periplasmic binding proteins and sugar binding domain of LacI family
MFLEKNFE_02339 3.79e-85 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MFLEKNFE_02340 4.54e-132 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MFLEKNFE_02341 5.82e-139 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
MFLEKNFE_02342 4.87e-55 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MFLEKNFE_02343 7.24e-291 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
MFLEKNFE_02344 4.54e-59 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MFLEKNFE_02345 1.57e-142 - - - S - - - Protein of unknown function (DUF1648)
MFLEKNFE_02346 4e-105 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
MFLEKNFE_02347 1.15e-144 yktB - - S - - - Belongs to the UPF0637 family
MFLEKNFE_02348 2.15e-137 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MFLEKNFE_02349 5.28e-105 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MFLEKNFE_02350 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MFLEKNFE_02351 2.22e-278 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MFLEKNFE_02352 7.66e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MFLEKNFE_02353 3.43e-76 - - - M - - - Glycosyl transferase family 2
MFLEKNFE_02355 4.08e-39 - - - - - - - -
MFLEKNFE_02356 8.53e-34 plnJ - - - - - - -
MFLEKNFE_02357 3.29e-32 plnK - - - - - - -
MFLEKNFE_02358 9.76e-153 - - - - - - - -
MFLEKNFE_02359 6.24e-25 plnR - - - - - - -
MFLEKNFE_02360 1.15e-43 - - - - - - - -
MFLEKNFE_02362 8.8e-265 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MFLEKNFE_02363 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MFLEKNFE_02364 8.38e-192 - - - S - - - hydrolase
MFLEKNFE_02365 2.35e-212 - - - K - - - Transcriptional regulator
MFLEKNFE_02366 1.69e-187 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MFLEKNFE_02367 2.24e-262 - - - EGP - - - Transporter, major facilitator family protein
MFLEKNFE_02368 9.2e-154 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MFLEKNFE_02369 5.32e-51 - - - - - - - -
MFLEKNFE_02370 1.51e-17 - - - L - - - LXG domain of WXG superfamily
MFLEKNFE_02371 4.92e-90 - - - S - - - Immunity protein 63
MFLEKNFE_02372 1.35e-22 - - - - - - - -
MFLEKNFE_02373 2.59e-84 - - - - - - - -
MFLEKNFE_02374 2.35e-52 - - - - - - - -
MFLEKNFE_02375 6.97e-45 - - - - - - - -
MFLEKNFE_02376 7.12e-226 - - - - - - - -
MFLEKNFE_02377 6.19e-73 - - - M - - - dTDP-4-dehydrorhamnose reductase activity
MFLEKNFE_02378 0.0 - - - M - - - domain protein
MFLEKNFE_02379 2.14e-174 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MFLEKNFE_02380 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
MFLEKNFE_02381 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MFLEKNFE_02382 0.0 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MFLEKNFE_02383 2.7e-230 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_02384 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MFLEKNFE_02385 4.06e-102 - 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA-DNA hybrid ribonuclease activity
MFLEKNFE_02386 1.03e-207 yneD - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLEKNFE_02387 1.49e-223 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
MFLEKNFE_02388 4.9e-103 accB3 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MFLEKNFE_02389 2.16e-103 - - - - - - - -
MFLEKNFE_02390 5.89e-108 - - - K - - - Winged helix-turn-helix transcription repressor, HrcA DNA-binding
MFLEKNFE_02391 3.25e-294 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MFLEKNFE_02392 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MFLEKNFE_02393 1.08e-71 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MFLEKNFE_02394 0.0 sufI - - Q - - - Multicopper oxidase
MFLEKNFE_02395 3.4e-153 rpiA2 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MFLEKNFE_02396 1.05e-132 zmp1 - - O - - - Zinc-dependent metalloprotease
MFLEKNFE_02397 8.95e-60 - - - - - - - -
MFLEKNFE_02398 6.6e-229 hicD1 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MFLEKNFE_02399 1.05e-308 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
MFLEKNFE_02400 0.0 - - - P - - - Major Facilitator Superfamily
MFLEKNFE_02401 2.39e-121 - - - K - - - Transcriptional regulator PadR-like family
MFLEKNFE_02402 2.76e-59 - - - - - - - -
MFLEKNFE_02403 9.42e-258 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MFLEKNFE_02404 8.13e-199 tagG - - U ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
MFLEKNFE_02405 1.1e-280 - - - - - - - -
MFLEKNFE_02406 2.21e-284 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MFLEKNFE_02407 6.71e-80 - - - S - - - CHY zinc finger
MFLEKNFE_02408 7.1e-226 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MFLEKNFE_02409 1.54e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MFLEKNFE_02410 1.29e-53 - - - - - - - -
MFLEKNFE_02411 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MFLEKNFE_02412 2.97e-41 - - - - - - - -
MFLEKNFE_02413 1.43e-170 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
MFLEKNFE_02414 2.36e-305 xylP1 - - G - - - MFS/sugar transport protein
MFLEKNFE_02415 2.98e-90 - - - - - - - -
MFLEKNFE_02416 2.41e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
MFLEKNFE_02417 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
MFLEKNFE_02418 2.21e-127 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
MFLEKNFE_02419 1.89e-159 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
MFLEKNFE_02420 4.08e-291 pts3C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFLEKNFE_02421 6.14e-53 - - - - - - - -
MFLEKNFE_02422 7.59e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MFLEKNFE_02423 3.63e-271 dho 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
MFLEKNFE_02424 5.06e-259 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
MFLEKNFE_02425 1.22e-166 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
MFLEKNFE_02426 2.02e-245 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
MFLEKNFE_02427 3.68e-125 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
MFLEKNFE_02428 5.78e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MFLEKNFE_02429 1.3e-211 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MFLEKNFE_02430 6.72e-203 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MFLEKNFE_02431 1.27e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MFLEKNFE_02432 7.55e-58 - - - S - - - Protein of unknown function (DUF2089)
MFLEKNFE_02433 2.21e-56 - - - - - - - -
MFLEKNFE_02434 1.68e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
MFLEKNFE_02435 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MFLEKNFE_02436 0.0 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MFLEKNFE_02437 0.0 pts5ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MFLEKNFE_02438 2.6e-185 - - - - - - - -
MFLEKNFE_02439 6.2e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MFLEKNFE_02440 7.84e-92 - - - - - - - -
MFLEKNFE_02441 1.48e-94 ywnA - - K - - - Transcriptional regulator
MFLEKNFE_02442 5.2e-156 - - - K - - - Bacterial regulatory proteins, tetR family
MFLEKNFE_02443 4.02e-301 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MFLEKNFE_02444 2.6e-149 - - - - - - - -
MFLEKNFE_02445 2.81e-55 - - - - - - - -
MFLEKNFE_02446 1.55e-55 - - - - - - - -
MFLEKNFE_02447 0.0 ydiC - - EGP - - - Major Facilitator
MFLEKNFE_02448 2.2e-86 - - - K - - - helix_turn_helix, mercury resistance
MFLEKNFE_02449 1.4e-314 hpk2 - - T - - - Histidine kinase
MFLEKNFE_02450 3.28e-166 rrp2 - - K - - - Transcriptional regulatory protein, C terminal
MFLEKNFE_02451 9.86e-65 - - - - - - - -
MFLEKNFE_02452 1.96e-167 yidA - - K - - - Helix-turn-helix domain, rpiR family
MFLEKNFE_02453 3.96e-310 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFLEKNFE_02454 3.35e-75 - - - - - - - -
MFLEKNFE_02455 2.87e-56 - - - - - - - -
MFLEKNFE_02456 1.45e-235 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MFLEKNFE_02457 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
MFLEKNFE_02458 1.49e-63 - - - - - - - -
MFLEKNFE_02459 2.04e-158 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MFLEKNFE_02460 1.17e-135 - - - K - - - transcriptional regulator
MFLEKNFE_02461 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MFLEKNFE_02462 8.31e-139 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MFLEKNFE_02463 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MFLEKNFE_02464 9.11e-52 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MFLEKNFE_02465 2.21e-207 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MFLEKNFE_02466 4.87e-156 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MFLEKNFE_02467 1.13e-171 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
MFLEKNFE_02468 4.75e-157 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MFLEKNFE_02469 3.42e-76 - - - M - - - Lysin motif
MFLEKNFE_02470 1.18e-172 rdrA - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MFLEKNFE_02471 2.08e-199 - 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MFLEKNFE_02472 1.13e-112 - - - GK - - - ROK family
MFLEKNFE_02473 1.79e-92 - - - GK - - - ROK family
MFLEKNFE_02474 1.91e-198 - - - U ko:K05340 - ko00000,ko02000 sugar transport
MFLEKNFE_02475 2.43e-209 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFLEKNFE_02476 1.23e-228 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
MFLEKNFE_02477 2.57e-128 - - - C - - - Nitroreductase family
MFLEKNFE_02478 6.04e-217 - - - S - - - Polyphosphate kinase 2 (PPK2)
MFLEKNFE_02479 4.32e-247 - - - S - - - domain, Protein
MFLEKNFE_02480 2.14e-183 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MFLEKNFE_02481 9.45e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MFLEKNFE_02482 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
MFLEKNFE_02483 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MFLEKNFE_02484 3e-98 yjcF - - S - - - Acetyltransferase (GNAT) domain
MFLEKNFE_02485 0.0 - - - M - - - domain protein
MFLEKNFE_02486 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MFLEKNFE_02487 3.1e-144 - - - S - - - Protein of unknown function (DUF1211)
MFLEKNFE_02488 1.45e-46 - - - - - - - -
MFLEKNFE_02489 2.33e-237 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MFLEKNFE_02490 3.4e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MFLEKNFE_02491 2.54e-17 rmeB - - K - - - transcriptional regulator, MerR family
MFLEKNFE_02492 1.71e-67 - - - S - - - Domain of unknown function (DU1801)
MFLEKNFE_02493 7.28e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MFLEKNFE_02494 3.72e-283 ysaA - - V - - - RDD family
MFLEKNFE_02495 7.54e-207 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
MFLEKNFE_02496 1.39e-276 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MFLEKNFE_02497 1.69e-151 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MFLEKNFE_02498 1.92e-299 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MFLEKNFE_02499 2.46e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
MFLEKNFE_02500 2.23e-142 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MFLEKNFE_02501 6.84e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MFLEKNFE_02502 1.27e-172 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MFLEKNFE_02503 2.49e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MFLEKNFE_02504 1.07e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
MFLEKNFE_02505 3.68e-256 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MFLEKNFE_02506 7.09e-125 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MFLEKNFE_02507 1.01e-176 yceF - - P ko:K05794 - ko00000 membrane
MFLEKNFE_02508 2.34e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
MFLEKNFE_02509 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
MFLEKNFE_02510 1.32e-178 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_02511 6.03e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MFLEKNFE_02512 1.13e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MFLEKNFE_02513 1.26e-212 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MFLEKNFE_02514 6.08e-312 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MFLEKNFE_02515 8.69e-295 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
MFLEKNFE_02516 3.45e-209 - - - S - - - Uncharacterised protein, DegV family COG1307
MFLEKNFE_02517 3.08e-241 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MFLEKNFE_02518 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MFLEKNFE_02519 9.2e-62 - - - - - - - -
MFLEKNFE_02520 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MFLEKNFE_02521 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
MFLEKNFE_02522 3.94e-140 aqpZ - - U ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MFLEKNFE_02523 8.13e-283 - - - S - - - associated with various cellular activities
MFLEKNFE_02524 9.34e-317 - - - S - - - Putative metallopeptidase domain
MFLEKNFE_02525 1.03e-65 - - - - - - - -
MFLEKNFE_02526 1.72e-135 yezE - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
MFLEKNFE_02527 7.83e-60 - - - - - - - -
MFLEKNFE_02528 4.23e-129 - - - S - - - WxL domain surface cell wall-binding
MFLEKNFE_02529 7.12e-159 - - - S - - - WxL domain surface cell wall-binding
MFLEKNFE_02530 1.83e-235 - - - S - - - Cell surface protein
MFLEKNFE_02531 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MFLEKNFE_02532 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
MFLEKNFE_02533 5.23e-107 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MFLEKNFE_02534 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MFLEKNFE_02535 1.82e-152 rcfA - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
MFLEKNFE_02536 2.98e-44 copZ - - P - - - Heavy-metal-associated domain
MFLEKNFE_02537 4.27e-126 dpsB - - P - - - Belongs to the Dps family
MFLEKNFE_02538 1.01e-26 - - - - - - - -
MFLEKNFE_02539 4.82e-55 yrkD - - S - - - Metal-sensitive transcriptional repressor
MFLEKNFE_02540 5.73e-73 trxA3 - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
MFLEKNFE_02541 9.44e-183 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MFLEKNFE_02542 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
MFLEKNFE_02543 2.93e-234 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MFLEKNFE_02544 3.04e-165 - - - S - - - Gram-negative-bacterium-type cell wall biogenesis
MFLEKNFE_02545 4.16e-175 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MFLEKNFE_02546 1.02e-231 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
MFLEKNFE_02547 1.37e-135 - - - K - - - transcriptional regulator
MFLEKNFE_02548 5.87e-207 - - - S ko:K07045 - ko00000 Amidohydrolase
MFLEKNFE_02549 1.43e-67 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
MFLEKNFE_02550 5.13e-138 - - - - - - - -
MFLEKNFE_02551 7.21e-168 sip - - L - - - Belongs to the 'phage' integrase family
MFLEKNFE_02552 4.94e-18 - - - K - - - transcriptional
MFLEKNFE_02553 7.63e-14 - - - - - - - -
MFLEKNFE_02557 5.76e-152 - - - S - - - Virulence-associated protein E
MFLEKNFE_02558 2.89e-21 - - - - - - - -
MFLEKNFE_02562 5.77e-81 - - - - - - - -
MFLEKNFE_02563 6.18e-71 - - - - - - - -
MFLEKNFE_02564 2.04e-107 - - - M - - - PFAM NLP P60 protein
MFLEKNFE_02565 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
MFLEKNFE_02566 4.45e-38 - - - - - - - -
MFLEKNFE_02567 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
MFLEKNFE_02568 3.81e-150 - - - K - - - Bacterial regulatory proteins, tetR family
MFLEKNFE_02569 5.33e-114 - - - K - - - Winged helix DNA-binding domain
MFLEKNFE_02570 1.63e-176 yesN - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
MFLEKNFE_02571 5.48e-171 - - - S - - - WxL domain surface cell wall-binding
MFLEKNFE_02572 1.36e-245 - - - S - - - Bacterial protein of unknown function (DUF916)
MFLEKNFE_02573 0.0 - - - - - - - -
MFLEKNFE_02574 2.58e-228 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFLEKNFE_02575 9.24e-85 accB1 - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin-requiring enzyme
MFLEKNFE_02576 1.98e-314 accC1 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase C-terminal domain
MFLEKNFE_02577 6.33e-185 accD1 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MFLEKNFE_02578 1.23e-177 accA1 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
MFLEKNFE_02579 2.9e-234 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MFLEKNFE_02580 7.53e-215 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
MFLEKNFE_02581 6.04e-227 - - - EG - - - EamA-like transporter family
MFLEKNFE_02582 3.3e-166 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MFLEKNFE_02583 4.57e-147 zmp2 - - O - - - Zinc-dependent metalloprotease
MFLEKNFE_02584 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MFLEKNFE_02585 1.62e-158 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MFLEKNFE_02586 5.96e-69 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
MFLEKNFE_02587 3.29e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
MFLEKNFE_02588 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MFLEKNFE_02589 4.91e-265 yacL - - S - - - domain protein
MFLEKNFE_02590 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MFLEKNFE_02591 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MFLEKNFE_02592 1.35e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MFLEKNFE_02593 1.49e-177 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MFLEKNFE_02594 5.87e-127 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
MFLEKNFE_02595 4.58e-130 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Sigma-70 region 2
MFLEKNFE_02596 4.55e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MFLEKNFE_02597 1e-39 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MFLEKNFE_02598 1.89e-128 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MFLEKNFE_02599 6.91e-203 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MFLEKNFE_02600 9.76e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MFLEKNFE_02601 2.69e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MFLEKNFE_02602 3.72e-105 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MFLEKNFE_02603 2.76e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MFLEKNFE_02604 1.31e-211 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MFLEKNFE_02605 1.9e-66 - - - L - - - nuclease
MFLEKNFE_02606 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MFLEKNFE_02607 2.37e-140 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MFLEKNFE_02608 2.47e-253 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFLEKNFE_02609 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFLEKNFE_02610 8.42e-50 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
MFLEKNFE_02611 6.7e-141 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MFLEKNFE_02612 7.57e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MFLEKNFE_02613 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MFLEKNFE_02614 2.05e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MFLEKNFE_02615 6.22e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MFLEKNFE_02616 1.01e-51 yaaL - - S - - - Protein of unknown function (DUF2508)
MFLEKNFE_02617 6.36e-153 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MFLEKNFE_02618 1.39e-70 yaaQ - - S - - - Cyclic-di-AMP receptor
MFLEKNFE_02619 2.33e-239 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MFLEKNFE_02620 8.46e-77 yabA - - L - - - Involved in initiation control of chromosome replication
MFLEKNFE_02621 1.53e-212 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MFLEKNFE_02622 3.17e-191 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MFLEKNFE_02623 2.86e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MFLEKNFE_02624 8.87e-269 phnW 2.6.1.37 - E ko:K03430 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000,ko01007 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
MFLEKNFE_02625 7.82e-62 phnX 3.11.1.1 - E ko:K05306 ko00440,ko01100,ko01120,map00440,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the HAD-like hydrolase superfamily. PhnX family
MFLEKNFE_02626 0.0 qacA - - EGP - - - Major Facilitator
MFLEKNFE_02627 2.48e-252 XK27_00915 - - C - - - Luciferase-like monooxygenase
MFLEKNFE_02628 1.23e-160 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MFLEKNFE_02629 7.05e-219 cpsY - - K - - - Transcriptional regulator, LysR family
MFLEKNFE_02630 5.13e-292 XK27_05470 - - E - - - Methionine synthase
MFLEKNFE_02632 1.85e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MFLEKNFE_02633 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFLEKNFE_02634 1.1e-200 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MFLEKNFE_02635 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MFLEKNFE_02636 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MFLEKNFE_02637 1.5e-227 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
MFLEKNFE_02638 6.84e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MFLEKNFE_02639 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MFLEKNFE_02640 1.27e-217 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MFLEKNFE_02641 2.4e-137 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MFLEKNFE_02642 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MFLEKNFE_02643 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MFLEKNFE_02644 1.56e-227 - - - K - - - Transcriptional regulator
MFLEKNFE_02645 3.21e-215 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MFLEKNFE_02646 3.8e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MFLEKNFE_02647 9.17e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MFLEKNFE_02648 1.07e-43 - - - S - - - YozE SAM-like fold
MFLEKNFE_02649 5.95e-203 - - - L - - - Phage integrase, N-terminal SAM-like domain
MFLEKNFE_02650 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MFLEKNFE_02651 4.49e-315 - - - M - - - Glycosyl transferase family group 2
MFLEKNFE_02652 1.98e-66 - - - - - - - -
MFLEKNFE_02653 9.22e-304 gshR1 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MFLEKNFE_02654 1.6e-93 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFLEKNFE_02655 6.39e-119 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MFLEKNFE_02656 0.0 tarL 2.7.8.14, 2.7.8.47 - H ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MFLEKNFE_02657 3.75e-246 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - H ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MFLEKNFE_02658 2.44e-242 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
MFLEKNFE_02659 7.15e-165 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MFLEKNFE_02660 6.75e-290 - - - - - - - -
MFLEKNFE_02661 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MFLEKNFE_02662 7.79e-78 - - - - - - - -
MFLEKNFE_02663 1.3e-174 - - - - - - - -
MFLEKNFE_02664 9.95e-108 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFLEKNFE_02665 9.24e-140 - - - K ko:K06977 - ko00000 acetyltransferase
MFLEKNFE_02666 0.0 - - - S - - - ABC transporter, ATP-binding protein
MFLEKNFE_02667 4.86e-279 - - - T - - - diguanylate cyclase
MFLEKNFE_02668 1.11e-45 - - - - - - - -
MFLEKNFE_02669 2.29e-48 - - - - - - - -
MFLEKNFE_02670 4.17e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
MFLEKNFE_02671 4.27e-223 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 NlpC/P60 family
MFLEKNFE_02672 8.16e-207 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MFLEKNFE_02674 2.68e-32 - - - - - - - -
MFLEKNFE_02675 8.05e-178 - - - F - - - NUDIX domain
MFLEKNFE_02676 6.83e-274 yceI - - EGP ko:K08369 - ko00000,ko02000 Major Facilitator
MFLEKNFE_02677 1.31e-64 - - - - - - - -
MFLEKNFE_02678 6.24e-120 - - - S - - - ECF-type riboflavin transporter, S component
MFLEKNFE_02680 1.26e-218 - - - EG - - - EamA-like transporter family
MFLEKNFE_02681 1.06e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
MFLEKNFE_02682 2.12e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
MFLEKNFE_02683 1.45e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
MFLEKNFE_02684 0.0 yclK - - T - - - Histidine kinase
MFLEKNFE_02685 5.23e-277 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
MFLEKNFE_02686 2.51e-200 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
MFLEKNFE_02687 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MFLEKNFE_02688 1.77e-116 - - - L - - - Phage integrase, N-terminal SAM-like domain
MFLEKNFE_02689 1.36e-193 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 DNA methyltransferase
MFLEKNFE_02690 1.09e-105 - - - S - - - AAA ATPase domain
MFLEKNFE_02692 3.8e-69 - - - - - - - -
MFLEKNFE_02693 6.19e-94 - - - E - - - IrrE N-terminal-like domain
MFLEKNFE_02694 1.32e-80 - - - K - - - Helix-turn-helix domain
MFLEKNFE_02695 2.06e-50 - - - K - - - Helix-turn-helix
MFLEKNFE_02697 7.6e-58 - - - - - - - -
MFLEKNFE_02699 6.34e-89 - - - - - - - -
MFLEKNFE_02700 1.11e-98 recT - - L ko:K07455 - ko00000,ko03400 RecT family
MFLEKNFE_02701 1.56e-71 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
MFLEKNFE_02702 3.71e-43 - - - L - - - Domain of unknown function (DUF4373)
MFLEKNFE_02703 1.2e-200 - - - S - - - IstB-like ATP binding protein
MFLEKNFE_02705 1.13e-76 - - - - - - - -
MFLEKNFE_02706 2.82e-91 rusA - - L - - - Endodeoxyribonuclease RusA
MFLEKNFE_02711 2.9e-17 - - - - - - - -
MFLEKNFE_02714 1.04e-46 - - - S - - - YopX protein
MFLEKNFE_02717 1.19e-22 - - - - - - - -
MFLEKNFE_02718 1.77e-105 - - - S - - - Phage transcriptional regulator, ArpU family
MFLEKNFE_02721 1.04e-20 - - - - - - - -
MFLEKNFE_02723 3.98e-37 - - - - - - - -
MFLEKNFE_02724 4.12e-88 - - - S - - - Terminase small subunit
MFLEKNFE_02725 2.61e-259 - - - S - - - Phage terminase large subunit
MFLEKNFE_02726 7.06e-251 - - - S - - - Phage portal protein, SPP1 Gp6-like
MFLEKNFE_02727 1.75e-123 - - - S - - - Phage Mu protein F like protein
MFLEKNFE_02728 3.45e-155 - - - S - - - Protein of unknown function (DUF1002)
MFLEKNFE_02729 1.58e-66 - - - - - - - -
MFLEKNFE_02730 6.47e-124 - - - K ko:K22041 - ko00000,ko03000 transcriptional regulator
MFLEKNFE_02731 5.94e-118 ymdB - - S - - - Macro domain protein
MFLEKNFE_02732 2.69e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MFLEKNFE_02733 1.05e-56 - - - S - - - Protein of unknown function (DUF1093)
MFLEKNFE_02734 2.07e-102 - - - S - - - Threonine/Serine exporter, ThrE
MFLEKNFE_02735 2.57e-171 - - - S - - - Putative threonine/serine exporter
MFLEKNFE_02736 1.36e-209 yvgN - - C - - - Aldo keto reductase
MFLEKNFE_02737 8.02e-205 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MFLEKNFE_02738 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MFLEKNFE_02739 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
MFLEKNFE_02740 1.14e-110 - - - F - - - Nucleoside 2-deoxyribosyltransferase
MFLEKNFE_02741 1.44e-99 - - - K - - - Domain of unknown function (DUF1836)
MFLEKNFE_02742 4.21e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
MFLEKNFE_02743 1.77e-282 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MFLEKNFE_02744 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
MFLEKNFE_02745 1.02e-83 - - - S - - - Protein of unknown function (DUF1398)
MFLEKNFE_02746 2.55e-65 - - - - - - - -
MFLEKNFE_02747 7.21e-35 - - - - - - - -
MFLEKNFE_02748 5.07e-314 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
MFLEKNFE_02749 2.07e-97 - - - S - - - COG NOG18757 non supervised orthologous group
MFLEKNFE_02750 4.26e-54 - - - - - - - -
MFLEKNFE_02751 4.83e-98 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
MFLEKNFE_02752 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MFLEKNFE_02753 5.12e-242 pva2 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MFLEKNFE_02754 2.55e-145 - - - S - - - VIT family
MFLEKNFE_02755 2.66e-155 - - - S - - - membrane
MFLEKNFE_02756 1.63e-203 - - - EG - - - EamA-like transporter family
MFLEKNFE_02757 2.52e-107 - - - S ko:K02348 - ko00000 GNAT family
MFLEKNFE_02758 3.57e-150 - - - GM - - - NmrA-like family
MFLEKNFE_02759 4.79e-21 - - - - - - - -
MFLEKNFE_02760 2.27e-74 - - - - - - - -
MFLEKNFE_02761 3.22e-103 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MFLEKNFE_02762 1.36e-112 - - - - - - - -
MFLEKNFE_02763 2.11e-82 - - - - - - - -
MFLEKNFE_02764 4.98e-275 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
MFLEKNFE_02765 1.7e-70 - - - - - - - -
MFLEKNFE_02766 3.46e-87 yeaO - - S - - - Protein of unknown function, DUF488
MFLEKNFE_02767 9.97e-94 spxA - - P ko:K16509 - ko00000 ArsC family
MFLEKNFE_02768 2.71e-89 - - - K ko:K22296 - ko00000,ko03000 Winged helix DNA-binding domain
MFLEKNFE_02769 3.9e-209 - - - GM - - - NmrA-like family
MFLEKNFE_02770 1.65e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
MFLEKNFE_02771 2.65e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MFLEKNFE_02772 2.71e-316 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MFLEKNFE_02773 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MFLEKNFE_02774 3.58e-36 - - - S - - - Belongs to the LOG family
MFLEKNFE_02775 5.56e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
MFLEKNFE_02776 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MFLEKNFE_02777 1.59e-242 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MFLEKNFE_02778 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MFLEKNFE_02779 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MFLEKNFE_02780 5.11e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MFLEKNFE_02781 9.48e-263 camS - - S - - - sex pheromone
MFLEKNFE_02782 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MFLEKNFE_02783 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MFLEKNFE_02784 1.39e-279 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MFLEKNFE_02785 1.13e-120 yebE - - S - - - UPF0316 protein
MFLEKNFE_02786 2.01e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MFLEKNFE_02787 5.66e-145 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
MFLEKNFE_02788 5.48e-235 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MFLEKNFE_02789 8.5e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MFLEKNFE_02790 2.53e-233 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MFLEKNFE_02791 7.68e-208 - - - S - - - L,D-transpeptidase catalytic domain
MFLEKNFE_02792 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MFLEKNFE_02793 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MFLEKNFE_02794 7.76e-234 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
MFLEKNFE_02795 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
MFLEKNFE_02796 0.0 - - - S ko:K06889 - ko00000 Alpha beta
MFLEKNFE_02797 2.56e-34 - - - - - - - -
MFLEKNFE_02798 4.37e-128 - - - S - - - ECF transporter, substrate-specific component
MFLEKNFE_02799 0.0 - - - E ko:K03294 - ko00000 Amino Acid
MFLEKNFE_02800 2.6e-212 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
MFLEKNFE_02801 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
MFLEKNFE_02802 6.5e-215 mleR - - K - - - LysR family
MFLEKNFE_02803 4.5e-113 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MFLEKNFE_02804 7.19e-94 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MFLEKNFE_02805 0.0 levR - - K - - - Sigma-54 interaction domain
MFLEKNFE_02806 9.05e-85 manO - - S - - - Domain of unknown function (DUF956)
MFLEKNFE_02807 1.87e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MFLEKNFE_02808 4.51e-172 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
MFLEKNFE_02809 6.46e-218 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MFLEKNFE_02810 3.4e-206 - - - G - - - Peptidase_C39 like family
MFLEKNFE_02813 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
MFLEKNFE_02814 4.34e-31 - - - - - - - -
MFLEKNFE_02817 2.93e-202 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MFLEKNFE_02818 2.84e-301 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MFLEKNFE_02819 6.25e-106 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MFLEKNFE_02820 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
MFLEKNFE_02821 6.3e-95 - - - - ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 -
MFLEKNFE_02822 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MFLEKNFE_02823 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MFLEKNFE_02824 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MFLEKNFE_02825 6.62e-176 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MFLEKNFE_02826 5.41e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MFLEKNFE_02827 2.92e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MFLEKNFE_02828 5.35e-175 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MFLEKNFE_02829 2.18e-186 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MFLEKNFE_02830 6.2e-245 ysdE - - P - - - Citrate transporter
MFLEKNFE_02831 1.31e-213 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
MFLEKNFE_02832 2.78e-71 - - - S - - - Cupin domain
MFLEKNFE_02833 9.02e-66 - - - S - - - Cupin 2, conserved barrel domain protein
MFLEKNFE_02837 1.5e-194 - - - S - - - Calcineurin-like phosphoesterase
MFLEKNFE_02838 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MFLEKNFE_02841 9.51e-317 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
MFLEKNFE_02842 1.81e-113 - - - - - - - -
MFLEKNFE_02843 5.7e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
MFLEKNFE_02844 3.81e-276 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MFLEKNFE_02845 2.19e-67 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
MFLEKNFE_02846 4.19e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MFLEKNFE_02847 1.71e-149 yqeK - - H - - - Hydrolase, HD family
MFLEKNFE_02848 1.06e-76 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MFLEKNFE_02849 6.65e-180 yqeM - - Q - - - Methyltransferase
MFLEKNFE_02850 3.55e-279 ylbM - - S - - - Belongs to the UPF0348 family
MFLEKNFE_02851 3.66e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MFLEKNFE_02852 1.3e-125 - - - S - - - Peptidase propeptide and YPEB domain
MFLEKNFE_02853 8.93e-223 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MFLEKNFE_02854 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MFLEKNFE_02855 1.8e-310 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MFLEKNFE_02856 1.38e-155 csrR - - K - - - response regulator
MFLEKNFE_02857 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MFLEKNFE_02858 1.93e-218 ubiA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MFLEKNFE_02859 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
MFLEKNFE_02860 2.36e-289 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MFLEKNFE_02861 1.21e-129 - - - S - - - SdpI/YhfL protein family
MFLEKNFE_02862 1.4e-208 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MFLEKNFE_02863 1.37e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MFLEKNFE_02864 4.46e-179 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MFLEKNFE_02865 1.72e-120 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MFLEKNFE_02866 1.09e-83 yodB - - K - - - Transcriptional regulator, HxlR family
MFLEKNFE_02867 6.88e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MFLEKNFE_02868 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MFLEKNFE_02869 6.11e-249 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MFLEKNFE_02870 7.5e-146 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MFLEKNFE_02871 1.09e-105 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MFLEKNFE_02872 9.72e-146 - - - S - - - membrane
MFLEKNFE_02873 5.72e-99 - - - K - - - LytTr DNA-binding domain
MFLEKNFE_02874 6.12e-72 yneR - - S - - - Belongs to the HesB IscA family
MFLEKNFE_02875 3.69e-130 - - - L - - - Integrase
MFLEKNFE_02876 8.79e-239 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MFLEKNFE_02877 5.05e-130 - - - M - - - Parallel beta-helix repeats
MFLEKNFE_02878 1.33e-82 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
MFLEKNFE_02879 2.02e-214 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MFLEKNFE_02880 6.89e-68 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
MFLEKNFE_02881 1.4e-62 - 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MFLEKNFE_02882 2.84e-117 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
MFLEKNFE_02883 1.16e-99 cps3J - - M - - - Domain of unknown function (DUF4422)
MFLEKNFE_02884 1.43e-28 - - - S - - - O-antigen ligase like membrane protein
MFLEKNFE_02885 7.12e-09 - - - V - - - Beta-lactamase
MFLEKNFE_02886 2.23e-10 cap5B - - D - - - NUBPL iron-transfer P-loop NTPase
MFLEKNFE_02888 6.08e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
MFLEKNFE_02889 3.98e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MFLEKNFE_02890 1.01e-199 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MFLEKNFE_02891 4.75e-267 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MFLEKNFE_02892 1.15e-281 pbpX - - V - - - Beta-lactamase
MFLEKNFE_02893 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MFLEKNFE_02894 2.9e-139 - - - - - - - -
MFLEKNFE_02895 7.62e-97 - - - - - - - -
MFLEKNFE_02897 1.93e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MFLEKNFE_02898 1.56e-313 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFLEKNFE_02899 3.23e-98 - - - T - - - Universal stress protein family
MFLEKNFE_02901 5.62e-316 yfmL - - L - - - DEAD DEAH box helicase
MFLEKNFE_02902 7.89e-245 mocA - - S - - - Oxidoreductase
MFLEKNFE_02903 6.22e-43 cspP - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MFLEKNFE_02904 7.34e-83 - - - S - - - Domain of unknown function (DUF4828)
MFLEKNFE_02905 1.1e-185 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MFLEKNFE_02906 5.63e-196 gntR - - K - - - rpiR family
MFLEKNFE_02907 2.87e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MFLEKNFE_02908 7.06e-307 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFLEKNFE_02909 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MFLEKNFE_02910 2.02e-39 - - - S - - - Protein of unknown function (DUF2929)
MFLEKNFE_02911 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MFLEKNFE_02912 8.69e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MFLEKNFE_02913 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MFLEKNFE_02914 2.51e-98 ytwI - - S - - - Protein of unknown function (DUF441)
MFLEKNFE_02915 7.94e-218 yitL - - S ko:K00243 - ko00000 S1 domain
MFLEKNFE_02916 3.13e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MFLEKNFE_02917 3.99e-92 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFLEKNFE_02918 1.18e-174 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MFLEKNFE_02919 1.3e-132 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MFLEKNFE_02920 2.69e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MFLEKNFE_02921 1.02e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MFLEKNFE_02922 3.38e-252 - - - S - - - Helix-turn-helix domain
MFLEKNFE_02923 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MFLEKNFE_02924 1.25e-39 - - - M - - - Lysin motif
MFLEKNFE_02925 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MFLEKNFE_02926 1.98e-281 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MFLEKNFE_02927 2.06e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MFLEKNFE_02928 5.57e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MFLEKNFE_02929 5.96e-284 XK27_05225 - - S - - - Tetratricopeptide repeat protein
MFLEKNFE_02930 3.71e-192 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MFLEKNFE_02931 1.39e-185 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MFLEKNFE_02932 8.95e-292 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MFLEKNFE_02933 6.46e-109 - - - - - - - -
MFLEKNFE_02934 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_02935 6.7e-241 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MFLEKNFE_02936 1.8e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MFLEKNFE_02937 2.88e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
MFLEKNFE_02938 2.4e-208 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
MFLEKNFE_02939 3.29e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
MFLEKNFE_02940 9.33e-48 yozE - - S - - - Belongs to the UPF0346 family
MFLEKNFE_02941 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MFLEKNFE_02942 8.16e-207 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
MFLEKNFE_02943 0.0 acdH 1.1.1.1, 1.2.1.10, 1.2.1.87 - C ko:K04072,ko:K13922 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Aldehyde dehydrogenase family
MFLEKNFE_02944 3.6e-242 - - - - - - - -
MFLEKNFE_02945 1.85e-208 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFLEKNFE_02946 5.05e-79 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MFLEKNFE_02947 2.06e-30 - - - - - - - -
MFLEKNFE_02948 2.05e-115 - - - K - - - acetyltransferase
MFLEKNFE_02949 1.88e-111 - - - K - - - GNAT family
MFLEKNFE_02950 8.08e-110 - - - S - - - ASCH
MFLEKNFE_02951 1.5e-124 - - - K - - - Cupin domain
MFLEKNFE_02952 1.46e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MFLEKNFE_02953 9e-190 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFLEKNFE_02954 5.58e-181 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MFLEKNFE_02955 5.3e-265 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MFLEKNFE_02956 9.25e-32 - - - U - - - Preprotein translocase subunit SecB
MFLEKNFE_02957 1.47e-35 - - - - - - - -
MFLEKNFE_02959 9.97e-50 - - - - - - - -
MFLEKNFE_02960 1.17e-288 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MFLEKNFE_02961 1.24e-99 - - - K - - - Transcriptional regulator
MFLEKNFE_02962 3.1e-101 - - - S ko:K02348 - ko00000 GNAT family
MFLEKNFE_02963 5.31e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MFLEKNFE_02964 1.67e-74 - - - - - - - -
MFLEKNFE_02965 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
MFLEKNFE_02966 6.88e-170 - - - - - - - -
MFLEKNFE_02967 7.42e-228 - - - - - - - -
MFLEKNFE_02968 8.48e-88 gcsH1 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Glycine cleavage H-protein
MFLEKNFE_02969 1.43e-82 - - - M - - - LysM domain protein
MFLEKNFE_02970 3.74e-125 - - - V - - - VanZ like family
MFLEKNFE_02971 1.87e-249 - - - V - - - Beta-lactamase
MFLEKNFE_02972 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
MFLEKNFE_02973 1.12e-206 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MFLEKNFE_02974 8.93e-71 - - - S - - - Pfam:DUF59
MFLEKNFE_02975 1.05e-223 ydhF - - S - - - Aldo keto reductase
MFLEKNFE_02976 1.66e-40 - - - FG - - - HIT domain
MFLEKNFE_02977 3.23e-73 - - - FG - - - HIT domain
MFLEKNFE_02978 5.09e-51 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
MFLEKNFE_02979 4.29e-101 - - - - - - - -
MFLEKNFE_02980 3.73e-157 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MFLEKNFE_02981 0.0 - - - U ko:K03451 - ko00000 Belongs to the BCCT transporter (TC 2.A.15) family
MFLEKNFE_02982 0.0 cadA - - P - - - P-type ATPase
MFLEKNFE_02984 4.21e-158 - - - S - - - YjbR
MFLEKNFE_02985 5.51e-284 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
MFLEKNFE_02986 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MFLEKNFE_02987 4.85e-257 glmS2 - - M - - - SIS domain
MFLEKNFE_02988 2.65e-52 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MFLEKNFE_02989 6.68e-238 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
MFLEKNFE_02990 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MFLEKNFE_02991 1.65e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MFLEKNFE_02992 1.26e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MFLEKNFE_02993 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MFLEKNFE_02994 1.19e-234 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MFLEKNFE_02995 3.4e-100 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MFLEKNFE_02996 1.12e-142 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
MFLEKNFE_02997 1.29e-235 - - - K - - - helix_turn_helix, arabinose operon control protein
MFLEKNFE_02998 5.06e-298 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
MFLEKNFE_02999 0.0 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
MFLEKNFE_03000 3.03e-295 - - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
MFLEKNFE_03001 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
MFLEKNFE_03002 4.73e-242 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MFLEKNFE_03003 1.25e-177 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MFLEKNFE_03004 1.15e-77 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFLEKNFE_03005 6.9e-124 - - - L - - - Resolvase, N terminal domain
MFLEKNFE_03006 5.49e-75 usp2 - - T - - - Belongs to the universal stress protein A family
MFLEKNFE_03007 3.17e-313 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MFLEKNFE_03008 1.09e-47 - - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
MFLEKNFE_03010 1.41e-163 - - - P - - - integral membrane protein, YkoY family
MFLEKNFE_03011 8.95e-222 - - - L - - - Transposase and inactivated derivatives, IS30 family
MFLEKNFE_03012 1.28e-69 - - - - - - - -
MFLEKNFE_03013 9.93e-303 - - - EGP - - - Major Facilitator Superfamily
MFLEKNFE_03014 0.0 sufI - - Q - - - Multicopper oxidase
MFLEKNFE_03015 1.26e-34 - - - - - - - -
MFLEKNFE_03016 1.57e-154 - - - L - - - Transposase and inactivated derivatives, IS30 family
MFLEKNFE_03017 2.03e-31 - - - S - - - Family of unknown function (DUF5388)
MFLEKNFE_03018 1.18e-184 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
MFLEKNFE_03019 5.3e-49 - - - L - - - DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MFLEKNFE_03020 3.02e-55 - - - S - - - Phage tail protein
MFLEKNFE_03021 0.0 - - - S - - - peptidoglycan catabolic process
MFLEKNFE_03022 1e-79 - - - S - - - Domain of unknown function (DUF2479)
MFLEKNFE_03023 8.36e-53 - - - - - - - -
MFLEKNFE_03025 3.56e-07 - - - S - - - Bacteriophage A118-like holin, Hol118
MFLEKNFE_03026 3.87e-158 - - - M - - - Glycosyl hydrolases family 25
MFLEKNFE_03027 2.75e-81 - - - S - - - Core-2/I-Branching enzyme
MFLEKNFE_03028 2.1e-33 - - - - - - - -
MFLEKNFE_03029 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MFLEKNFE_03030 7.68e-106 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MFLEKNFE_03031 2.74e-112 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MFLEKNFE_03032 2.08e-213 drrA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MFLEKNFE_03033 8.81e-166 drrB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MFLEKNFE_03034 1.75e-295 - - - M - - - O-Antigen ligase
MFLEKNFE_03035 8.34e-165 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MFLEKNFE_03036 1.09e-249 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MFLEKNFE_03037 2.14e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MFLEKNFE_03038 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MFLEKNFE_03039 4.98e-73 - - - S - - - Phage tail protein
MFLEKNFE_03040 2.58e-249 - - - S - - - peptidoglycan catabolic process
MFLEKNFE_03042 4.05e-41 - - - S - - - Pfam:Phage_TAC_12
MFLEKNFE_03043 1.46e-127 - - - S - - - Phage major tail protein 2
MFLEKNFE_03045 7.61e-48 - - - S - - - exonuclease activity
MFLEKNFE_03046 3.2e-41 - - - - - - - -
MFLEKNFE_03047 1.56e-60 - - - S - - - Phage gp6-like head-tail connector protein
MFLEKNFE_03048 1.86e-153 - - - - - - - -
MFLEKNFE_03049 9.33e-41 - - - S - - - aminoacyl-tRNA ligase activity
MFLEKNFE_03050 1.53e-26 - - - - - - - -
MFLEKNFE_03051 2.33e-100 - - - - - - - -
MFLEKNFE_03052 7.4e-23 - - - - - - - -
MFLEKNFE_03053 4.43e-223 - - - M - - - Peptidase family S41
MFLEKNFE_03054 2.56e-124 - - - K - - - Helix-turn-helix domain
MFLEKNFE_03055 5.63e-225 - - - L - - - Transposase and inactivated derivatives, IS30 family
MFLEKNFE_03056 5.62e-49 kdpE - - KT ko:K02483,ko:K07667 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
MFLEKNFE_03057 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MFLEKNFE_03058 1.41e-195 gbuA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
MFLEKNFE_03059 9.64e-129 gbuB - - E ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MFLEKNFE_03060 1.03e-129 gbuC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MFLEKNFE_03061 6.79e-25 isp - - L - - - Transposase
MFLEKNFE_03062 1.19e-22 - - - T - - - Belongs to the universal stress protein A family
MFLEKNFE_03063 2.75e-127 tnp1216 - - L ko:K07498 - ko00000 DDE domain
MFLEKNFE_03064 1.02e-234 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
MFLEKNFE_03066 2.94e-97 repB - - L - - - Initiator Replication protein
MFLEKNFE_03067 1.13e-15 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
MFLEKNFE_03069 7.87e-45 - - - - - - - -
MFLEKNFE_03071 1.2e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
MFLEKNFE_03072 4.17e-55 - - - K - - - prlF antitoxin for toxin YhaV_toxin
MFLEKNFE_03073 3.77e-139 - - - L - - - Integrase
MFLEKNFE_03074 5.7e-71 - - - S - - - Fic/DOC family
MFLEKNFE_03075 4.21e-55 - - - - - - - -
MFLEKNFE_03076 3.99e-36 - - - - - - - -
MFLEKNFE_03077 0.0 traA - - L - - - MobA/MobL family
MFLEKNFE_03078 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
MFLEKNFE_03079 5.32e-81 - - - M - - - Cna protein B-type domain
MFLEKNFE_03080 6.46e-221 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
MFLEKNFE_03081 1.04e-98 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MFLEKNFE_03083 2.65e-52 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MFLEKNFE_03084 1.51e-234 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
MFLEKNFE_03085 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MFLEKNFE_03086 1.43e-71 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
MFLEKNFE_03087 4.49e-74 - - - L - - - Transposase DDE domain
MFLEKNFE_03088 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
MFLEKNFE_03089 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MFLEKNFE_03090 1.35e-55 - - - S - - - COG NOG38524 non supervised orthologous group
MFLEKNFE_03113 3.98e-126 - - - S - - - Plasmid replication protein
MFLEKNFE_03114 1.29e-254 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MFLEKNFE_03115 1.37e-249 - - - L - - - Transposase and inactivated derivatives, IS30 family
MFLEKNFE_03116 3.13e-99 - - - L - - - Transposase DDE domain
MFLEKNFE_03117 3.33e-89 - - - L - - - Putative transposase of IS4/5 family (DUF4096)

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)