ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NMMECHGA_00001 5.55e-301 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NMMECHGA_00002 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NMMECHGA_00003 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
NMMECHGA_00004 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NMMECHGA_00005 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
NMMECHGA_00006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMMECHGA_00007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMMECHGA_00008 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NMMECHGA_00011 2.14e-232 yaaC - - S - - - YaaC-like Protein
NMMECHGA_00012 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NMMECHGA_00013 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NMMECHGA_00014 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NMMECHGA_00015 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NMMECHGA_00016 7.68e-277 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NMMECHGA_00018 4.17e-156 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
NMMECHGA_00019 7.51e-145 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
NMMECHGA_00020 2.63e-271 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
NMMECHGA_00021 1.05e-120 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
NMMECHGA_00022 2.47e-107 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NMMECHGA_00023 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMMECHGA_00024 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NMMECHGA_00025 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NMMECHGA_00026 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
NMMECHGA_00027 2.16e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
NMMECHGA_00028 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NMMECHGA_00031 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
NMMECHGA_00032 2.21e-131 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NMMECHGA_00033 5.64e-257 yaaN - - P - - - Belongs to the TelA family
NMMECHGA_00034 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
NMMECHGA_00035 3.84e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NMMECHGA_00036 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
NMMECHGA_00037 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
NMMECHGA_00038 2.42e-236 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NMMECHGA_00039 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
NMMECHGA_00040 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
NMMECHGA_00041 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
NMMECHGA_00042 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
NMMECHGA_00043 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NMMECHGA_00044 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
NMMECHGA_00045 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NMMECHGA_00046 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
NMMECHGA_00047 1.91e-283 yabE - - T - - - protein conserved in bacteria
NMMECHGA_00048 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NMMECHGA_00049 2.05e-198 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NMMECHGA_00050 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
NMMECHGA_00051 5.32e-53 veg - - S - - - protein conserved in bacteria
NMMECHGA_00052 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NMMECHGA_00053 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NMMECHGA_00054 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
NMMECHGA_00055 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NMMECHGA_00056 4.27e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NMMECHGA_00057 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NMMECHGA_00058 4.16e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NMMECHGA_00059 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NMMECHGA_00060 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
NMMECHGA_00061 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NMMECHGA_00062 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
NMMECHGA_00063 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMMECHGA_00064 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NMMECHGA_00065 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NMMECHGA_00066 1.91e-66 yabP - - S - - - Sporulation protein YabP
NMMECHGA_00067 5.21e-138 yabQ - - S - - - spore cortex biosynthesis protein
NMMECHGA_00068 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NMMECHGA_00069 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NMMECHGA_00072 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
NMMECHGA_00073 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NMMECHGA_00074 2.41e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
NMMECHGA_00075 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NMMECHGA_00076 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
NMMECHGA_00077 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NMMECHGA_00078 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NMMECHGA_00079 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NMMECHGA_00080 2.23e-194 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
NMMECHGA_00081 4.4e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NMMECHGA_00082 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NMMECHGA_00083 5.98e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
NMMECHGA_00084 2.27e-216 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
NMMECHGA_00085 3.32e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NMMECHGA_00086 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NMMECHGA_00087 2.64e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NMMECHGA_00088 1.81e-41 yazB - - K - - - transcriptional
NMMECHGA_00089 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NMMECHGA_00090 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NMMECHGA_00091 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NMMECHGA_00101 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NMMECHGA_00102 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NMMECHGA_00103 1.42e-75 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
NMMECHGA_00104 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NMMECHGA_00105 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
NMMECHGA_00106 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NMMECHGA_00107 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NMMECHGA_00108 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
NMMECHGA_00109 1.82e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NMMECHGA_00110 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NMMECHGA_00111 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NMMECHGA_00112 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
NMMECHGA_00113 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NMMECHGA_00114 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NMMECHGA_00115 8.65e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMMECHGA_00116 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
NMMECHGA_00117 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
NMMECHGA_00118 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NMMECHGA_00119 1.19e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NMMECHGA_00120 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NMMECHGA_00121 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NMMECHGA_00122 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NMMECHGA_00123 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NMMECHGA_00124 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NMMECHGA_00125 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMMECHGA_00126 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMMECHGA_00127 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
NMMECHGA_00128 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NMMECHGA_00129 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NMMECHGA_00130 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NMMECHGA_00131 1.36e-285 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NMMECHGA_00132 1.2e-235 ybaC - - S - - - Alpha/beta hydrolase family
NMMECHGA_00133 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NMMECHGA_00134 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NMMECHGA_00135 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NMMECHGA_00136 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NMMECHGA_00137 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NMMECHGA_00138 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NMMECHGA_00139 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NMMECHGA_00140 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NMMECHGA_00141 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NMMECHGA_00142 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NMMECHGA_00143 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NMMECHGA_00144 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NMMECHGA_00145 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NMMECHGA_00146 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NMMECHGA_00147 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NMMECHGA_00148 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NMMECHGA_00149 2.58e-120 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NMMECHGA_00150 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NMMECHGA_00151 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NMMECHGA_00152 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NMMECHGA_00153 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NMMECHGA_00154 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NMMECHGA_00155 6.17e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NMMECHGA_00156 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NMMECHGA_00157 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NMMECHGA_00158 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NMMECHGA_00159 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NMMECHGA_00160 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NMMECHGA_00161 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMMECHGA_00162 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NMMECHGA_00163 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMMECHGA_00164 1.1e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMMECHGA_00165 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMMECHGA_00166 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NMMECHGA_00167 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NMMECHGA_00168 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NMMECHGA_00169 1.19e-183 ybaJ - - Q - - - Methyltransferase domain
NMMECHGA_00170 4.21e-90 ybaK - - S - - - Protein of unknown function (DUF2521)
NMMECHGA_00171 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NMMECHGA_00172 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NMMECHGA_00173 1.04e-122 gerD - - - ko:K06294 - ko00000 -
NMMECHGA_00174 2.42e-132 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
NMMECHGA_00175 1.23e-180 pdaB - - G - - - Polysaccharide deacetylase
NMMECHGA_00176 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NMMECHGA_00179 1.16e-99 - - - L - - - Phage integrase, N-terminal SAM-like domain
NMMECHGA_00180 6e-33 xkdA - - E - - - IrrE N-terminal-like domain
NMMECHGA_00181 1.18e-27 - - - - - - - -
NMMECHGA_00182 5.92e-67 bldD - - K ko:K07110,ko:K21572 - ko00000,ko02000,ko03000 domain, Protein
NMMECHGA_00183 1.12e-18 - - - K - - - Helix-turn-helix XRE-family like proteins
NMMECHGA_00184 1.58e-19 - - - S - - - Helix-turn-helix domain
NMMECHGA_00185 2.18e-55 - - - - - - - -
NMMECHGA_00189 5.4e-228 - - - D - - - nuclear chromosome segregation
NMMECHGA_00191 5.14e-146 - - - L ko:K07455 - ko00000,ko03400 RecT family
NMMECHGA_00192 3.56e-131 - - - S - - - Metallo-beta-lactamase superfamily
NMMECHGA_00194 1.04e-34 - - - L - - - primosome component and related proteins
NMMECHGA_00196 2.63e-227 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NMMECHGA_00199 1.12e-75 rusA - - L - - - Endodeoxyribonuclease RusA
NMMECHGA_00200 4.32e-98 - - - - - - - -
NMMECHGA_00203 7.84e-34 - - - - - - - -
NMMECHGA_00206 1e-24 - - - S - - - Putative phage abortive infection protein
NMMECHGA_00207 8.56e-51 - - - - - - - -
NMMECHGA_00210 3.54e-52 - - - - - - - -
NMMECHGA_00212 0.000102 - - - - - - - -
NMMECHGA_00215 4.88e-80 - - - K - - - DNA binding
NMMECHGA_00216 2.8e-124 - - - - - - - -
NMMECHGA_00217 5.5e-42 - - - - - - - -
NMMECHGA_00218 3.85e-109 - - - - - - - -
NMMECHGA_00219 9.09e-296 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
NMMECHGA_00220 3.26e-316 yqbA - - S - - - portal protein
NMMECHGA_00221 7.41e-187 - - - S - - - Phage Mu protein F like protein
NMMECHGA_00223 2.25e-128 yqbD - - L - - - Putative phage serine protease XkdF
NMMECHGA_00224 1.23e-188 xkdG - - S - - - Phage capsid family
NMMECHGA_00225 5.35e-34 - - - S - - - YqbF, hypothetical protein domain
NMMECHGA_00226 1.33e-60 - - - S - - - Protein of unknown function (DUF3199)
NMMECHGA_00227 3.38e-74 yqbH - - S - - - Domain of unknown function (DUF3599)
NMMECHGA_00228 4.72e-110 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NMMECHGA_00229 1.16e-86 yqbJ - - - - - - -
NMMECHGA_00230 6.01e-33 - - - - - - - -
NMMECHGA_00231 5.87e-311 xkdK - - S - - - Phage tail sheath C-terminal domain
NMMECHGA_00232 6.75e-96 xkdM - - S - - - Phage tail tube protein
NMMECHGA_00234 1.42e-86 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
NMMECHGA_00235 0.0 xkdO - - L - - - Transglycosylase SLT domain
NMMECHGA_00236 2.46e-151 xkdP - - S - - - Lysin motif
NMMECHGA_00237 6.31e-226 xkdQ - - G - - - NLP P60 protein
NMMECHGA_00238 4.92e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
NMMECHGA_00239 8.65e-87 xkdS - - S - - - Protein of unknown function (DUF2634)
NMMECHGA_00240 1.44e-233 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NMMECHGA_00241 2.34e-127 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
NMMECHGA_00242 3.25e-49 - - - - - - - -
NMMECHGA_00243 3.47e-202 - - - - - - - -
NMMECHGA_00244 2.99e-57 xkdW - - S - - - XkdW protein
NMMECHGA_00245 1.2e-26 - - - - - - - -
NMMECHGA_00246 3.23e-193 xepA - - - - - - -
NMMECHGA_00247 4.4e-75 - - - S - - - Bacteriophage holin family
NMMECHGA_00248 1.89e-157 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NMMECHGA_00249 3.87e-47 - - - - - - - -
NMMECHGA_00250 2.28e-25 - - - - - - - -
NMMECHGA_00251 7.64e-36 - - - - - - - -
NMMECHGA_00252 5.49e-228 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
NMMECHGA_00253 1.27e-200 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
NMMECHGA_00255 9.58e-50 - - - S - - - YolD-like protein
NMMECHGA_00256 8.2e-13 - - - - - - - -
NMMECHGA_00257 1.95e-08 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NMMECHGA_00263 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NMMECHGA_00264 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NMMECHGA_00265 1.56e-08 - - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
NMMECHGA_00266 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NMMECHGA_00267 2.34e-203 ybaS - - S - - - Na -dependent transporter
NMMECHGA_00268 6.65e-183 ybbA - - S ko:K07017 - ko00000 Putative esterase
NMMECHGA_00269 3.51e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMMECHGA_00270 1.17e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMMECHGA_00271 5.12e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
NMMECHGA_00272 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
NMMECHGA_00273 4.91e-304 ybbC - - S - - - protein conserved in bacteria
NMMECHGA_00274 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
NMMECHGA_00275 7.64e-287 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
NMMECHGA_00276 8.5e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NMMECHGA_00277 2.17e-184 ybbH - - K - - - transcriptional
NMMECHGA_00278 1.54e-197 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NMMECHGA_00279 2.67e-106 ybbJ - - J - - - acetyltransferase
NMMECHGA_00280 8.75e-94 ybbK - - S - - - Protein of unknown function (DUF523)
NMMECHGA_00286 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NMMECHGA_00287 4.18e-147 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NMMECHGA_00288 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NMMECHGA_00289 2.65e-286 ybbR - - S - - - protein conserved in bacteria
NMMECHGA_00290 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NMMECHGA_00291 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NMMECHGA_00293 1.75e-225 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NMMECHGA_00294 1.52e-155 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
NMMECHGA_00295 2.14e-128 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NMMECHGA_00296 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NMMECHGA_00297 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
NMMECHGA_00298 3.29e-121 ybcF - - P - - - carbonic anhydrase
NMMECHGA_00300 4.6e-63 - - - - - - - -
NMMECHGA_00301 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
NMMECHGA_00302 9.45e-67 - - - K - - - Helix-turn-helix domain
NMMECHGA_00303 6.59e-258 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
NMMECHGA_00305 7.24e-304 - - - J - - - 4Fe-4S single cluster domain
NMMECHGA_00306 0.0 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
NMMECHGA_00307 1.15e-171 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NMMECHGA_00308 6.33e-310 skfF - - S - - - ABC transporter
NMMECHGA_00309 3.88e-118 - - - C - - - HEAT repeats
NMMECHGA_00310 3.4e-102 - - - CO - - - Thioredoxin-like domain
NMMECHGA_00311 2.1e-15 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NMMECHGA_00312 4.48e-193 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NMMECHGA_00313 6.9e-158 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
NMMECHGA_00314 2.44e-213 - - - T - - - His Kinase A (phospho-acceptor) domain
NMMECHGA_00316 9.33e-177 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
NMMECHGA_00317 3.67e-193 ybdN - - - - - - -
NMMECHGA_00318 5.19e-273 ybdO - - S - - - Domain of unknown function (DUF4885)
NMMECHGA_00319 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NMMECHGA_00320 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
NMMECHGA_00321 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
NMMECHGA_00322 7.18e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
NMMECHGA_00323 4.43e-313 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
NMMECHGA_00324 1.11e-54 ybyB - - - - - - -
NMMECHGA_00325 0.0 ybeC - - E - - - amino acid
NMMECHGA_00326 4.05e-210 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
NMMECHGA_00327 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
NMMECHGA_00328 1.02e-46 - - - S - - - Protein of unknown function (DUF2651)
NMMECHGA_00329 1.66e-215 ybfA - - K - - - FR47-like protein
NMMECHGA_00330 2.52e-282 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
NMMECHGA_00332 8.37e-205 ybfH - - EG - - - EamA-like transporter family
NMMECHGA_00333 2.12e-187 ybfI - - K - - - AraC-like ligand binding domain
NMMECHGA_00334 8.89e-269 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NMMECHGA_00335 5.04e-230 mpr - - M - - - Belongs to the peptidase S1B family
NMMECHGA_00337 5.34e-214 - - - S - - - Alpha/beta hydrolase family
NMMECHGA_00338 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NMMECHGA_00339 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
NMMECHGA_00340 2.06e-188 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NMMECHGA_00341 1.25e-56 ybfN - - - - - - -
NMMECHGA_00342 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
NMMECHGA_00343 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
NMMECHGA_00344 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMMECHGA_00345 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NMMECHGA_00346 2.48e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NMMECHGA_00347 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
NMMECHGA_00349 4.01e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NMMECHGA_00350 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NMMECHGA_00351 4.14e-230 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
NMMECHGA_00353 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NMMECHGA_00354 2.59e-230 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NMMECHGA_00355 4.3e-285 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMMECHGA_00356 2.68e-205 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
NMMECHGA_00357 1.79e-216 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
NMMECHGA_00358 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMMECHGA_00359 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NMMECHGA_00360 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NMMECHGA_00361 2.57e-158 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
NMMECHGA_00362 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
NMMECHGA_00363 2.03e-221 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
NMMECHGA_00364 2.51e-32 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
NMMECHGA_00365 6.24e-61 eamA1 - - EG - - - spore germination
NMMECHGA_00366 2.96e-91 eamA1 - - EG - - - spore germination
NMMECHGA_00367 2.24e-161 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMMECHGA_00368 8.83e-214 ycbM - - T - - - Histidine kinase
NMMECHGA_00369 9.2e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_00370 3.9e-146 - - - S - - - ABC-2 family transporter protein
NMMECHGA_00371 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
NMMECHGA_00372 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
NMMECHGA_00373 6.17e-16 ycbR - - T - - - vWA found in TerF C terminus
NMMECHGA_00374 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
NMMECHGA_00375 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NMMECHGA_00376 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NMMECHGA_00377 1.4e-153 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NMMECHGA_00378 2.41e-259 ycbU - - E - - - Selenocysteine lyase
NMMECHGA_00379 7.17e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
NMMECHGA_00380 1.54e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NMMECHGA_00381 3.56e-259 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NMMECHGA_00382 2.7e-145 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NMMECHGA_00383 1.24e-77 - - - S - - - RDD family
NMMECHGA_00384 1.01e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
NMMECHGA_00385 4.16e-211 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NMMECHGA_00386 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NMMECHGA_00387 5.41e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NMMECHGA_00388 6.29e-254 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NMMECHGA_00389 6.81e-222 yccK - - C - - - Aldo keto reductase
NMMECHGA_00390 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
NMMECHGA_00391 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NMMECHGA_00392 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NMMECHGA_00393 3.76e-123 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NMMECHGA_00394 6.72e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
NMMECHGA_00395 9.73e-180 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
NMMECHGA_00396 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NMMECHGA_00397 2.27e-220 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NMMECHGA_00398 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NMMECHGA_00399 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NMMECHGA_00400 1.34e-234 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMMECHGA_00401 3.75e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
NMMECHGA_00402 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NMMECHGA_00403 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NMMECHGA_00404 4.1e-176 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
NMMECHGA_00405 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
NMMECHGA_00406 2.96e-245 yceH - - P - - - Belongs to the TelA family
NMMECHGA_00407 3.84e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
NMMECHGA_00408 9.79e-260 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
NMMECHGA_00409 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NMMECHGA_00410 3.66e-292 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
NMMECHGA_00411 6.02e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NMMECHGA_00412 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NMMECHGA_00413 1.97e-276 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
NMMECHGA_00414 0.0 ycgA - - S - - - Membrane
NMMECHGA_00415 2.72e-105 ycgB - - - - - - -
NMMECHGA_00416 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
NMMECHGA_00417 1.69e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NMMECHGA_00418 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NMMECHGA_00419 0.0 mdr - - EGP - - - the major facilitator superfamily
NMMECHGA_00420 1.51e-100 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
NMMECHGA_00421 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
NMMECHGA_00422 3.73e-195 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
NMMECHGA_00423 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NMMECHGA_00424 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
NMMECHGA_00425 5.24e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NMMECHGA_00426 2.17e-139 tmrB - - S - - - AAA domain
NMMECHGA_00427 4.28e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NMMECHGA_00428 3.56e-184 - - - Q - - - ubiE/COQ5 methyltransferase family
NMMECHGA_00429 8.01e-228 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
NMMECHGA_00430 9.05e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
NMMECHGA_00431 2.6e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
NMMECHGA_00432 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NMMECHGA_00433 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NMMECHGA_00434 5.98e-315 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMMECHGA_00435 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
NMMECHGA_00436 7.72e-195 ycgQ - - S ko:K08986 - ko00000 membrane
NMMECHGA_00437 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
NMMECHGA_00438 7.24e-204 ycgS - - I - - - alpha/beta hydrolase fold
NMMECHGA_00439 1.3e-239 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NMMECHGA_00440 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NMMECHGA_00441 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
NMMECHGA_00442 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NMMECHGA_00443 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NMMECHGA_00444 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
NMMECHGA_00445 6.43e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NMMECHGA_00446 2.65e-216 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
NMMECHGA_00447 2.96e-40 - - - M - - - ErfK YbiS YcfS YnhG
NMMECHGA_00448 2.72e-71 - - - M - - - ErfK YbiS YcfS YnhG
NMMECHGA_00449 3.09e-287 yciC - - S - - - GTPases (G3E family)
NMMECHGA_00450 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NMMECHGA_00451 7.26e-185 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NMMECHGA_00452 1.69e-56 yckC - - S - - - membrane
NMMECHGA_00453 1.01e-68 yckD - - S - - - Protein of unknown function (DUF2680)
NMMECHGA_00454 1.29e-58 - - - K - - - MarR family
NMMECHGA_00455 9e-32 - - - - - - - -
NMMECHGA_00456 2.72e-153 - - - S - - - AAA domain
NMMECHGA_00457 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NMMECHGA_00458 2.77e-90 nin - - S - - - Competence protein J (ComJ)
NMMECHGA_00459 1.6e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
NMMECHGA_00460 2.82e-258 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NMMECHGA_00461 1.95e-127 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
NMMECHGA_00462 9.74e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
NMMECHGA_00463 6.05e-86 hxlR - - K - - - transcriptional
NMMECHGA_00464 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMMECHGA_00465 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMMECHGA_00466 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
NMMECHGA_00467 1.34e-178 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
NMMECHGA_00468 3.87e-282 - - - EGP - - - Major Facilitator Superfamily
NMMECHGA_00469 8.93e-124 - - - S - - - YcxB-like protein
NMMECHGA_00470 6.88e-207 ycxC - - EG - - - EamA-like transporter family
NMMECHGA_00471 0.0 ycxD - - K - - - GntR family transcriptional regulator
NMMECHGA_00472 4.76e-145 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
NMMECHGA_00473 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
NMMECHGA_00474 5.85e-171 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NMMECHGA_00475 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NMMECHGA_00476 3.03e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NMMECHGA_00477 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
NMMECHGA_00478 3.72e-139 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NMMECHGA_00479 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NMMECHGA_00480 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
NMMECHGA_00481 9.83e-106 yclD - - - - - - -
NMMECHGA_00482 8.75e-199 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
NMMECHGA_00483 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
NMMECHGA_00484 0.0 yclG - - M - - - Pectate lyase superfamily protein
NMMECHGA_00486 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
NMMECHGA_00487 3.26e-294 gerKC - - S ko:K06297 - ko00000 spore germination
NMMECHGA_00488 1.48e-250 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
NMMECHGA_00489 4.82e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NMMECHGA_00490 1.45e-275 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
NMMECHGA_00491 5.43e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMMECHGA_00492 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NMMECHGA_00493 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NMMECHGA_00495 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NMMECHGA_00496 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NMMECHGA_00497 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMMECHGA_00498 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMMECHGA_00499 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_00500 5.72e-213 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
NMMECHGA_00501 0.0 ycnB - - EGP - - - the major facilitator superfamily
NMMECHGA_00502 5.87e-198 ycnC - - K - - - Transcriptional regulator
NMMECHGA_00503 2.48e-173 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NMMECHGA_00504 1.68e-60 ycnE - - S - - - Monooxygenase
NMMECHGA_00505 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NMMECHGA_00506 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMMECHGA_00507 3.9e-303 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NMMECHGA_00508 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMMECHGA_00509 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
NMMECHGA_00510 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMMECHGA_00511 3.99e-134 ycnI - - S - - - protein conserved in bacteria
NMMECHGA_00512 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
NMMECHGA_00513 1.22e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NMMECHGA_00514 4.67e-75 - - - - - - - -
NMMECHGA_00515 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
NMMECHGA_00516 4.81e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NMMECHGA_00517 4.21e-266 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
NMMECHGA_00518 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
NMMECHGA_00520 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NMMECHGA_00521 3.32e-141 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
NMMECHGA_00522 1.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
NMMECHGA_00524 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NMMECHGA_00525 1.82e-179 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
NMMECHGA_00526 2.78e-273 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
NMMECHGA_00527 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
NMMECHGA_00528 4.84e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
NMMECHGA_00529 5.72e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
NMMECHGA_00530 1.55e-170 kipR - - K - - - Transcriptional regulator
NMMECHGA_00531 5.94e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
NMMECHGA_00533 7.67e-66 yczJ - - S - - - biosynthesis
NMMECHGA_00534 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
NMMECHGA_00535 1.27e-221 ycsN - - S - - - Oxidoreductase
NMMECHGA_00536 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
NMMECHGA_00537 0.0 ydaB - - IQ - - - acyl-CoA ligase
NMMECHGA_00538 1.17e-126 ydaC - - Q - - - Methyltransferase domain
NMMECHGA_00539 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMMECHGA_00540 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
NMMECHGA_00541 6.6e-134 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NMMECHGA_00542 5.24e-101 ydaG - - S - - - general stress protein
NMMECHGA_00543 1.87e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NMMECHGA_00544 2.12e-59 ydzA - - EGP - - - Domain of unknown function (DUF3817)
NMMECHGA_00545 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NMMECHGA_00546 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NMMECHGA_00547 2.96e-265 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
NMMECHGA_00548 1.33e-194 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
NMMECHGA_00549 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
NMMECHGA_00550 1.93e-304 ydaM - - M - - - Glycosyl transferase family group 2
NMMECHGA_00551 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
NMMECHGA_00552 0.0 ydaO - - E - - - amino acid
NMMECHGA_00553 7.09e-57 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NMMECHGA_00554 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NMMECHGA_00556 3.67e-34 - - - - - - - -
NMMECHGA_00557 1.54e-90 sdpB - - S - - - Protein conserved in bacteria
NMMECHGA_00559 2.14e-53 - - - - - - - -
NMMECHGA_00560 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NMMECHGA_00561 1.67e-42 ydaS - - S - - - membrane
NMMECHGA_00562 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
NMMECHGA_00563 8.69e-190 ydbA - - P - - - EcsC protein family
NMMECHGA_00564 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
NMMECHGA_00565 3.09e-78 ydbB - - G - - - Cupin domain
NMMECHGA_00566 2.12e-81 ydbC - - S - - - Domain of unknown function (DUF4937
NMMECHGA_00567 3.71e-196 ydbD - - P ko:K07217 - ko00000 Catalase
NMMECHGA_00568 5.82e-250 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NMMECHGA_00569 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NMMECHGA_00570 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NMMECHGA_00571 3.64e-289 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMMECHGA_00572 3.25e-231 ydbI - - S - - - AI-2E family transporter
NMMECHGA_00573 2.09e-215 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_00574 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NMMECHGA_00575 9.32e-70 ydbL - - - - - - -
NMMECHGA_00576 4.31e-279 ydbM - - I - - - acyl-CoA dehydrogenase
NMMECHGA_00577 1.49e-26 - - - S - - - Fur-regulated basic protein B
NMMECHGA_00579 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMMECHGA_00580 4.19e-75 ydbP - - CO - - - Thioredoxin
NMMECHGA_00581 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NMMECHGA_00582 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NMMECHGA_00583 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NMMECHGA_00584 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
NMMECHGA_00585 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
NMMECHGA_00586 2.96e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
NMMECHGA_00587 1.6e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NMMECHGA_00588 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
NMMECHGA_00589 7.21e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NMMECHGA_00590 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NMMECHGA_00591 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NMMECHGA_00592 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
NMMECHGA_00593 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
NMMECHGA_00594 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NMMECHGA_00595 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
NMMECHGA_00596 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
NMMECHGA_00597 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NMMECHGA_00598 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMMECHGA_00599 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
NMMECHGA_00600 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
NMMECHGA_00601 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NMMECHGA_00610 8.36e-86 - - - - - - - -
NMMECHGA_00611 5.7e-11 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NMMECHGA_00614 3.48e-111 - - - - - - - -
NMMECHGA_00615 5.86e-39 ydjM - - M - - - Lytic transglycolase
NMMECHGA_00616 2.89e-215 - - - U - - - Involved in the tonB-independent uptake of proteins
NMMECHGA_00617 3.02e-95 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMMECHGA_00618 5.98e-156 nicK - - L ko:K07467 - ko00000 Replication initiation factor
NMMECHGA_00619 5.76e-40 nicK - - L ko:K07467 - ko00000 Replication initiation factor
NMMECHGA_00620 3.97e-49 - - - - - - - -
NMMECHGA_00623 2.24e-60 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NMMECHGA_00624 5.41e-56 - - - - - - - -
NMMECHGA_00625 1.45e-179 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NMMECHGA_00626 1.8e-45 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
NMMECHGA_00627 1.21e-52 - - - - - - - -
NMMECHGA_00628 4.75e-245 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
NMMECHGA_00629 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
NMMECHGA_00630 1.45e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
NMMECHGA_00631 1.19e-182 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NMMECHGA_00632 1.04e-211 - - - K - - - AraC-like ligand binding domain
NMMECHGA_00633 1.86e-219 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NMMECHGA_00634 2.75e-211 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
NMMECHGA_00635 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMMECHGA_00636 1.88e-277 ydeG - - EGP - - - Major facilitator superfamily
NMMECHGA_00637 4.56e-70 ydeH - - - - - - -
NMMECHGA_00638 3.88e-133 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
NMMECHGA_00639 8.57e-141 - - - - - - - -
NMMECHGA_00640 2.4e-41 - - - S - - - SNARE associated Golgi protein
NMMECHGA_00641 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
NMMECHGA_00642 2.44e-110 - - - K - - - Transcriptional regulator C-terminal region
NMMECHGA_00643 4.66e-197 ydeK - - EG - - - -transporter
NMMECHGA_00644 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMMECHGA_00645 2.49e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
NMMECHGA_00646 2.72e-117 - - - S ko:K07002 - ko00000 Serine hydrolase
NMMECHGA_00647 1.5e-74 - - - K - - - HxlR-like helix-turn-helix
NMMECHGA_00648 1.96e-195 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NMMECHGA_00649 5.03e-91 ydeP - - K - - - Transcriptional regulator
NMMECHGA_00650 2e-141 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
NMMECHGA_00651 4.82e-258 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
NMMECHGA_00652 2.16e-135 ydeS - - K - - - Transcriptional regulator
NMMECHGA_00653 1.05e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
NMMECHGA_00654 4.12e-293 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NMMECHGA_00655 1.33e-185 - - - J - - - GNAT acetyltransferase
NMMECHGA_00656 3.93e-190 - - - K - - - Transcriptional regulator
NMMECHGA_00657 1.45e-157 nodB1 - - G - - - deacetylase
NMMECHGA_00658 9.24e-202 - - - - - - - -
NMMECHGA_00659 2.51e-284 - - - T - - - GHKL domain
NMMECHGA_00660 9.3e-159 - - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
NMMECHGA_00661 9.77e-191 - - - EG - - - EamA-like transporter family
NMMECHGA_00662 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMMECHGA_00663 9.91e-150 ydfE - - S - - - Flavin reductase like domain
NMMECHGA_00664 8.33e-156 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NMMECHGA_00665 3.92e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NMMECHGA_00667 1.31e-249 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMMECHGA_00668 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMMECHGA_00669 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
NMMECHGA_00670 9.25e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NMMECHGA_00671 5.02e-188 - - - K - - - Bacterial transcription activator, effector binding domain
NMMECHGA_00672 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMMECHGA_00673 8.74e-139 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
NMMECHGA_00674 6.41e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NMMECHGA_00675 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
NMMECHGA_00676 8.92e-73 ydfQ - - CO - - - Thioredoxin
NMMECHGA_00677 1.69e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
NMMECHGA_00678 7.9e-41 - - - - - - - -
NMMECHGA_00680 3.27e-127 ydfR - - S - - - Protein of unknown function (DUF421)
NMMECHGA_00681 7.06e-157 ydfS - - S - - - Protein of unknown function (DUF421)
NMMECHGA_00682 2.57e-89 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NMMECHGA_00683 1.53e-47 ydgA - - S - - - Spore germination protein gerPA/gerPF
NMMECHGA_00684 8.97e-47 ydgB - - S - - - Spore germination protein gerPA/gerPF
NMMECHGA_00685 1.72e-127 ydgC - - K - - - Bacterial regulatory proteins, tetR family
NMMECHGA_00686 3.33e-69 - - - S - - - DoxX-like family
NMMECHGA_00687 1.97e-111 yycN - - K - - - Acetyltransferase
NMMECHGA_00688 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
NMMECHGA_00689 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NMMECHGA_00690 3.44e-117 - - - S - - - DinB family
NMMECHGA_00691 3.44e-105 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NMMECHGA_00692 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
NMMECHGA_00693 6.42e-147 ydgI - - C - - - nitroreductase
NMMECHGA_00694 3.29e-90 - - - K - - - Winged helix DNA-binding domain
NMMECHGA_00695 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
NMMECHGA_00696 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
NMMECHGA_00697 7.45e-158 ydhC - - K - - - FCD
NMMECHGA_00698 1.42e-306 ydhD - - M - - - Glycosyl hydrolase
NMMECHGA_00699 1.59e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NMMECHGA_00700 8.64e-163 - - - - - - - -
NMMECHGA_00701 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
NMMECHGA_00702 1.12e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
NMMECHGA_00704 1.61e-109 - - - K - - - Acetyltransferase (GNAT) domain
NMMECHGA_00705 1.9e-231 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NMMECHGA_00706 9.44e-129 ydhK - - M - - - Protein of unknown function (DUF1541)
NMMECHGA_00707 1.04e-253 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
NMMECHGA_00708 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NMMECHGA_00709 4.82e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NMMECHGA_00710 3.23e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMMECHGA_00711 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NMMECHGA_00712 7.44e-169 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
NMMECHGA_00713 8.54e-215 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
NMMECHGA_00714 9.47e-236 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NMMECHGA_00715 1.59e-269 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
NMMECHGA_00716 4.02e-201 ydhU - - P ko:K07217 - ko00000 Catalase
NMMECHGA_00719 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NMMECHGA_00722 3.06e-237 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NMMECHGA_00723 2.13e-111 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
NMMECHGA_00724 6.33e-157 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
NMMECHGA_00725 1.71e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NMMECHGA_00726 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NMMECHGA_00727 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
NMMECHGA_00728 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NMMECHGA_00729 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NMMECHGA_00730 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NMMECHGA_00731 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NMMECHGA_00732 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
NMMECHGA_00733 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NMMECHGA_00734 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NMMECHGA_00735 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NMMECHGA_00736 3.4e-283 ykuG - - M - - - peptidoglycan-binding domain-containing protein
NMMECHGA_00738 1.38e-75 - - - - - - - -
NMMECHGA_00739 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
NMMECHGA_00740 3.55e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
NMMECHGA_00741 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
NMMECHGA_00742 1.8e-222 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NMMECHGA_00743 7.61e-148 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
NMMECHGA_00744 3.64e-228 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NMMECHGA_00745 1.12e-167 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
NMMECHGA_00746 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
NMMECHGA_00747 3.23e-247 - - - S - - - Ion transport 2 domain protein
NMMECHGA_00748 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NMMECHGA_00749 2.88e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
NMMECHGA_00750 7.29e-84 ydjM - - M - - - Lytic transglycolase
NMMECHGA_00751 1.98e-208 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
NMMECHGA_00753 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
NMMECHGA_00754 1.03e-201 - - - I - - - Alpha/beta hydrolase family
NMMECHGA_00755 1.18e-227 yeaA - - S - - - Protein of unknown function (DUF4003)
NMMECHGA_00756 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
NMMECHGA_00757 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NMMECHGA_00758 1.02e-197 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMMECHGA_00759 1.68e-227 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
NMMECHGA_00760 1.93e-286 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NMMECHGA_00761 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
NMMECHGA_00762 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NMMECHGA_00763 6.9e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NMMECHGA_00764 5.85e-165 yebC - - M - - - Membrane
NMMECHGA_00766 1.08e-119 yebE - - S - - - UPF0316 protein
NMMECHGA_00767 3.13e-38 yebG - - S - - - NETI protein
NMMECHGA_00768 6.53e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NMMECHGA_00769 9.39e-278 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NMMECHGA_00770 1.98e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NMMECHGA_00771 2.78e-166 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NMMECHGA_00772 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMMECHGA_00773 1.91e-166 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMMECHGA_00774 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMMECHGA_00775 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NMMECHGA_00776 1.4e-239 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NMMECHGA_00777 1.04e-136 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NMMECHGA_00778 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NMMECHGA_00779 4.67e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NMMECHGA_00780 1.06e-95 - - - K - - - helix_turn_helix ASNC type
NMMECHGA_00781 2.13e-294 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
NMMECHGA_00782 1.2e-37 - - - S - - - Protein of unknown function (DUF2892)
NMMECHGA_00783 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
NMMECHGA_00784 6.74e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
NMMECHGA_00785 7.62e-68 yerC - - S - - - protein conserved in bacteria
NMMECHGA_00786 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
NMMECHGA_00788 1.1e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NMMECHGA_00789 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NMMECHGA_00790 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NMMECHGA_00791 2.41e-279 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
NMMECHGA_00792 4.95e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
NMMECHGA_00793 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
NMMECHGA_00794 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMMECHGA_00795 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMMECHGA_00796 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NMMECHGA_00797 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMMECHGA_00798 1.26e-191 yerO - - K - - - Transcriptional regulator
NMMECHGA_00799 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NMMECHGA_00800 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NMMECHGA_00801 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMMECHGA_00802 4.32e-32 - - - - - - - -
NMMECHGA_00803 2.1e-109 - - - S - - - Protein of unknown function, DUF600
NMMECHGA_00804 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
NMMECHGA_00805 7.57e-226 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
NMMECHGA_00807 4.44e-274 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
NMMECHGA_00809 1.09e-162 yeeN - - K - - - transcriptional regulatory protein
NMMECHGA_00811 1.35e-127 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_00812 1.42e-106 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
NMMECHGA_00813 2.84e-185 yesF - - GM - - - NAD(P)H-binding
NMMECHGA_00814 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
NMMECHGA_00815 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
NMMECHGA_00816 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
NMMECHGA_00817 4.15e-131 yesJ - - K - - - Acetyltransferase (GNAT) family
NMMECHGA_00819 3.48e-130 yesL - - S - - - Protein of unknown function, DUF624
NMMECHGA_00820 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMMECHGA_00821 5.2e-253 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
NMMECHGA_00822 8.33e-314 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NMMECHGA_00823 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NMMECHGA_00824 8.84e-211 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NMMECHGA_00825 8e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
NMMECHGA_00826 0.0 yesS - - K - - - Transcriptional regulator
NMMECHGA_00827 8.39e-170 - - - E - - - GDSL-like Lipase/Acylhydrolase
NMMECHGA_00828 7.22e-163 yesU - - S - - - Domain of unknown function (DUF1961)
NMMECHGA_00829 9.47e-144 - - - S - - - Protein of unknown function, DUF624
NMMECHGA_00830 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
NMMECHGA_00831 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
NMMECHGA_00832 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
NMMECHGA_00833 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
NMMECHGA_00834 0.0 yetA - - - - - - -
NMMECHGA_00835 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NMMECHGA_00836 6.84e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
NMMECHGA_00837 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NMMECHGA_00838 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
NMMECHGA_00839 6.06e-156 yetF - - S - - - membrane
NMMECHGA_00840 4.5e-71 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
NMMECHGA_00841 2.38e-83 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMMECHGA_00842 1.75e-44 - - - - - - - -
NMMECHGA_00843 4.37e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NMMECHGA_00844 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
NMMECHGA_00845 2.55e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
NMMECHGA_00846 4.56e-115 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
NMMECHGA_00847 4.9e-263 yetM - - CH - - - FAD binding domain
NMMECHGA_00848 6.96e-173 - - - M - - - Membrane
NMMECHGA_00849 3.38e-250 yetN - - S - - - Protein of unknown function (DUF3900)
NMMECHGA_00850 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NMMECHGA_00851 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NMMECHGA_00852 2.41e-187 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
NMMECHGA_00853 1.37e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
NMMECHGA_00854 5.22e-227 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
NMMECHGA_00855 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
NMMECHGA_00856 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
NMMECHGA_00857 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NMMECHGA_00858 4.49e-169 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NMMECHGA_00859 3.41e-312 yfnA - - E ko:K03294 - ko00000 amino acid
NMMECHGA_00860 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMMECHGA_00861 5.14e-161 yfmS - - NT - - - chemotaxis protein
NMMECHGA_00862 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NMMECHGA_00863 2.07e-90 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
NMMECHGA_00864 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
NMMECHGA_00865 5.94e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
NMMECHGA_00866 1.12e-48 - - - - - - - -
NMMECHGA_00867 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NMMECHGA_00868 2.08e-263 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
NMMECHGA_00869 1.94e-100 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
NMMECHGA_00870 1.71e-241 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
NMMECHGA_00871 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NMMECHGA_00872 4.23e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMMECHGA_00873 4.72e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMMECHGA_00874 4.77e-220 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NMMECHGA_00875 7.44e-32 - - - S - - - Protein of unknown function (DUF3212)
NMMECHGA_00876 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
NMMECHGA_00877 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
NMMECHGA_00878 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NMMECHGA_00879 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NMMECHGA_00880 1.61e-153 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NMMECHGA_00881 1.14e-229 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
NMMECHGA_00882 1.53e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NMMECHGA_00883 4.17e-193 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NMMECHGA_00884 1.67e-276 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NMMECHGA_00885 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NMMECHGA_00886 4e-156 yflK - - S - - - protein conserved in bacteria
NMMECHGA_00887 4.49e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
NMMECHGA_00888 6.9e-27 yflI - - - - - - -
NMMECHGA_00889 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
NMMECHGA_00890 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NMMECHGA_00891 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NMMECHGA_00892 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NMMECHGA_00893 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
NMMECHGA_00894 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
NMMECHGA_00895 5.09e-33 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
NMMECHGA_00896 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NMMECHGA_00897 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
NMMECHGA_00898 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
NMMECHGA_00899 6.16e-160 frp - - C - - - nitroreductase
NMMECHGA_00900 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NMMECHGA_00901 5.48e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NMMECHGA_00902 6.21e-266 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NMMECHGA_00903 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
NMMECHGA_00904 2.14e-110 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NMMECHGA_00905 2.53e-67 yfkI - - S - - - gas vesicle protein
NMMECHGA_00906 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NMMECHGA_00907 2.74e-11 - - - - - - - -
NMMECHGA_00908 3.84e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NMMECHGA_00909 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
NMMECHGA_00910 3.69e-189 yfkD - - S - - - YfkD-like protein
NMMECHGA_00911 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
NMMECHGA_00912 1.76e-283 yfkA - - S - - - YfkB-like domain
NMMECHGA_00913 3.26e-36 yfjT - - - - - - -
NMMECHGA_00914 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
NMMECHGA_00915 5.62e-193 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NMMECHGA_00916 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
NMMECHGA_00917 5.57e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NMMECHGA_00918 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMMECHGA_00919 7.17e-58 - - - S - - - YfzA-like protein
NMMECHGA_00920 4.72e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NMMECHGA_00921 4.55e-109 yfjM - - S - - - Psort location Cytoplasmic, score
NMMECHGA_00923 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NMMECHGA_00924 5.32e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NMMECHGA_00925 4.47e-260 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMMECHGA_00926 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NMMECHGA_00927 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
NMMECHGA_00928 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
NMMECHGA_00929 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
NMMECHGA_00930 6.64e-110 - - - S - - - Family of unknown function (DUF5381)
NMMECHGA_00931 7.16e-160 yfjC - - - - - - -
NMMECHGA_00932 2.41e-241 yfjB - - - - - - -
NMMECHGA_00933 1.6e-60 yfjA - - S - - - Belongs to the WXG100 family
NMMECHGA_00934 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NMMECHGA_00935 2.13e-181 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
NMMECHGA_00936 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NMMECHGA_00937 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
NMMECHGA_00938 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
NMMECHGA_00939 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NMMECHGA_00940 2.01e-84 yfiD3 - - S - - - DoxX
NMMECHGA_00941 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
NMMECHGA_00943 3.43e-272 baeS - - T - - - Histidine kinase
NMMECHGA_00944 6.07e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
NMMECHGA_00945 3.08e-214 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_00946 4.37e-266 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NMMECHGA_00947 1.7e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NMMECHGA_00948 1.89e-128 padR - - K - - - transcriptional
NMMECHGA_00949 1.59e-52 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NMMECHGA_00950 6.42e-63 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NMMECHGA_00951 2.46e-248 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NMMECHGA_00952 4e-128 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
NMMECHGA_00953 0.0 yfiU - - EGP - - - the major facilitator superfamily
NMMECHGA_00954 2.11e-103 yfiV - - K - - - transcriptional
NMMECHGA_00955 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NMMECHGA_00956 2.31e-232 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NMMECHGA_00957 1.04e-223 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMMECHGA_00958 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMMECHGA_00959 7.3e-213 yfhB - - S - - - PhzF family
NMMECHGA_00960 2.87e-138 yfhC - - C - - - nitroreductase
NMMECHGA_00961 8.86e-35 yfhD - - S - - - YfhD-like protein
NMMECHGA_00963 3.79e-220 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
NMMECHGA_00964 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
NMMECHGA_00965 9.26e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
NMMECHGA_00966 1.65e-266 yfhI - - EGP - - - -transporter
NMMECHGA_00967 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
NMMECHGA_00968 8.95e-60 yfhJ - - S - - - WVELL protein
NMMECHGA_00969 1.2e-117 yfhK - - T - - - Bacterial SH3 domain homologues
NMMECHGA_00970 1.81e-65 yfhL - - S - - - SdpI/YhfL protein family
NMMECHGA_00971 4.59e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
NMMECHGA_00972 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NMMECHGA_00973 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NMMECHGA_00974 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
NMMECHGA_00975 1.31e-265 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
NMMECHGA_00976 1.73e-48 yfhS - - - - - - -
NMMECHGA_00977 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMMECHGA_00978 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
NMMECHGA_00979 2.01e-49 ygaB - - S - - - YgaB-like protein
NMMECHGA_00980 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NMMECHGA_00981 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
NMMECHGA_00982 1.08e-237 ygaE - - S - - - Membrane
NMMECHGA_00983 3.8e-311 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NMMECHGA_00984 1.19e-112 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
NMMECHGA_00985 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NMMECHGA_00986 5.46e-74 ygzB - - S - - - UPF0295 protein
NMMECHGA_00987 1.17e-214 ygxA - - S - - - Nucleotidyltransferase-like
NMMECHGA_00988 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NMMECHGA_01005 1.83e-184 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
NMMECHGA_01006 1.58e-36 - - - - - - - -
NMMECHGA_01007 2.06e-167 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
NMMECHGA_01008 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NMMECHGA_01009 0.0 ygaK - - C - - - Berberine and berberine like
NMMECHGA_01011 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NMMECHGA_01012 2.06e-185 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NMMECHGA_01013 4.19e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
NMMECHGA_01014 5.86e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NMMECHGA_01015 9.35e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
NMMECHGA_01017 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NMMECHGA_01018 6.58e-101 ygaO - - - - - - -
NMMECHGA_01019 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_01021 7.82e-147 yhzB - - S - - - B3/4 domain
NMMECHGA_01022 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NMMECHGA_01023 7.62e-223 yhbB - - S - - - Putative amidase domain
NMMECHGA_01024 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NMMECHGA_01025 3.97e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
NMMECHGA_01026 9.3e-96 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NMMECHGA_01027 2.6e-106 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NMMECHGA_01028 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
NMMECHGA_01029 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
NMMECHGA_01030 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
NMMECHGA_01031 3.8e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
NMMECHGA_01032 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
NMMECHGA_01033 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
NMMECHGA_01034 3.95e-59 yhcC - - - - - - -
NMMECHGA_01035 1.03e-69 - - - - - - - -
NMMECHGA_01036 3.37e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_01037 2.66e-155 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_01038 1.07e-211 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_01039 1.99e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NMMECHGA_01040 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
NMMECHGA_01041 7.44e-193 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NMMECHGA_01042 6.79e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
NMMECHGA_01043 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMMECHGA_01044 5.96e-66 yhcM - - - - - - -
NMMECHGA_01045 1.09e-110 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NMMECHGA_01046 2.29e-226 yhcP - - - - - - -
NMMECHGA_01047 9.74e-146 yhcQ - - M - - - Spore coat protein
NMMECHGA_01048 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NMMECHGA_01049 3.07e-135 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
NMMECHGA_01050 1.12e-216 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NMMECHGA_01051 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
NMMECHGA_01052 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
NMMECHGA_01053 2.5e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
NMMECHGA_01054 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NMMECHGA_01055 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NMMECHGA_01056 2.55e-133 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NMMECHGA_01057 6.65e-195 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NMMECHGA_01058 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NMMECHGA_01059 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NMMECHGA_01060 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
NMMECHGA_01061 8.92e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
NMMECHGA_01062 5.44e-144 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMMECHGA_01063 9.43e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
NMMECHGA_01064 1.65e-51 yhdB - - S - - - YhdB-like protein
NMMECHGA_01065 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
NMMECHGA_01066 1.61e-273 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NMMECHGA_01067 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
NMMECHGA_01068 8.74e-306 ygxB - - M - - - Conserved TM helix
NMMECHGA_01069 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
NMMECHGA_01070 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
NMMECHGA_01071 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NMMECHGA_01072 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_01073 2.24e-262 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NMMECHGA_01074 1.92e-206 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMMECHGA_01075 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
NMMECHGA_01076 4.29e-310 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NMMECHGA_01077 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMMECHGA_01078 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMMECHGA_01079 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
NMMECHGA_01080 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
NMMECHGA_01081 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NMMECHGA_01082 6.74e-244 yhdN - - C - - - Aldo keto reductase
NMMECHGA_01083 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NMMECHGA_01084 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NMMECHGA_01085 1.42e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
NMMECHGA_01086 1.46e-283 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NMMECHGA_01087 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
NMMECHGA_01088 1.68e-64 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NMMECHGA_01089 1.43e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NMMECHGA_01090 9.03e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NMMECHGA_01091 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
NMMECHGA_01092 1.51e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
NMMECHGA_01093 1.14e-177 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NMMECHGA_01094 1.18e-192 nodB1 - - G - - - deacetylase
NMMECHGA_01095 1.83e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NMMECHGA_01096 2.54e-303 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NMMECHGA_01097 1.5e-106 nhaX - - T - - - Belongs to the universal stress protein A family
NMMECHGA_01098 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NMMECHGA_01099 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NMMECHGA_01100 3.71e-140 yheG - - GM - - - NAD(P)H-binding
NMMECHGA_01101 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
NMMECHGA_01102 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
NMMECHGA_01103 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
NMMECHGA_01104 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
NMMECHGA_01105 7.19e-260 yheB - - S - - - Belongs to the UPF0754 family
NMMECHGA_01106 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
NMMECHGA_01107 9.11e-262 yhaZ - - L - - - DNA alkylation repair enzyme
NMMECHGA_01108 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
NMMECHGA_01109 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
NMMECHGA_01110 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
NMMECHGA_01111 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NMMECHGA_01113 3.62e-169 yhaR - - I - - - enoyl-CoA hydratase
NMMECHGA_01114 2.29e-36 - - - S - - - YhzD-like protein
NMMECHGA_01115 2.27e-214 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_01116 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
NMMECHGA_01117 3.69e-298 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
NMMECHGA_01118 0.0 yhaN - - L - - - AAA domain
NMMECHGA_01119 2.13e-227 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
NMMECHGA_01120 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
NMMECHGA_01121 3.63e-176 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NMMECHGA_01122 1.99e-116 yhaK - - S - - - Putative zincin peptidase
NMMECHGA_01123 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
NMMECHGA_01124 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
NMMECHGA_01125 1.74e-54 yhaH - - S - - - YtxH-like protein
NMMECHGA_01126 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
NMMECHGA_01127 2.06e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NMMECHGA_01128 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NMMECHGA_01129 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
NMMECHGA_01130 2.98e-270 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NMMECHGA_01131 3.37e-160 ecsC - - S - - - EcsC protein family
NMMECHGA_01132 2.1e-289 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NMMECHGA_01133 6.07e-309 yhfA - - C - - - membrane
NMMECHGA_01134 2.25e-41 - - - C - - - Rubrerythrin
NMMECHGA_01135 3.77e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NMMECHGA_01136 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NMMECHGA_01137 4.32e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NMMECHGA_01138 3.28e-229 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NMMECHGA_01139 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NMMECHGA_01140 6.76e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_01141 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
NMMECHGA_01142 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMMECHGA_01143 6.57e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
NMMECHGA_01144 1.55e-252 yhfE - - G - - - peptidase M42
NMMECHGA_01145 6.22e-93 - - - S - - - ASCH
NMMECHGA_01146 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMMECHGA_01147 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NMMECHGA_01148 1.17e-244 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NMMECHGA_01149 1.5e-143 yhfK - - GM - - - NmrA-like family
NMMECHGA_01150 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NMMECHGA_01151 2.78e-85 yhfM - - - - - - -
NMMECHGA_01152 7.92e-307 yhfN - - O - - - Peptidase M48
NMMECHGA_01153 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NMMECHGA_01154 7.28e-101 - - - K - - - acetyltransferase
NMMECHGA_01155 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
NMMECHGA_01156 3.23e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NMMECHGA_01157 1.6e-139 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
NMMECHGA_01158 4.96e-249 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NMMECHGA_01159 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NMMECHGA_01160 3.46e-117 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NMMECHGA_01161 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
NMMECHGA_01162 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
NMMECHGA_01163 1.07e-201 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMMECHGA_01164 9.84e-45 yhzC - - S - - - IDEAL
NMMECHGA_01165 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
NMMECHGA_01166 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NMMECHGA_01167 1.14e-53 yhjA - - S - - - Excalibur calcium-binding domain
NMMECHGA_01168 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMMECHGA_01169 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
NMMECHGA_01170 4.13e-78 yhjD - - - - - - -
NMMECHGA_01171 2.82e-140 yhjE - - S - - - SNARE associated Golgi protein
NMMECHGA_01172 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NMMECHGA_01173 0.0 yhjG - - CH - - - FAD binding domain
NMMECHGA_01174 4.68e-121 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
NMMECHGA_01177 4.97e-269 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
NMMECHGA_01178 3.98e-257 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
NMMECHGA_01179 3.59e-203 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
NMMECHGA_01180 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
NMMECHGA_01181 4.36e-239 yhjM - - K - - - Transcriptional regulator
NMMECHGA_01182 1.02e-258 yhjN - - S ko:K07120 - ko00000 membrane
NMMECHGA_01183 1.93e-267 - - - EGP - - - Transmembrane secretion effector
NMMECHGA_01184 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
NMMECHGA_01185 9.3e-102 yhjR - - S - - - Rubrerythrin
NMMECHGA_01186 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
NMMECHGA_01187 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NMMECHGA_01188 2.32e-279 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NMMECHGA_01189 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
NMMECHGA_01190 6.4e-65 yisB - - V - - - COG1403 Restriction endonuclease
NMMECHGA_01191 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
NMMECHGA_01192 1.53e-83 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
NMMECHGA_01193 6.07e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
NMMECHGA_01194 3.34e-92 gerPC - - S ko:K06301 - ko00000 Spore germination protein
NMMECHGA_01195 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
NMMECHGA_01196 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
NMMECHGA_01197 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
NMMECHGA_01198 1.88e-222 cotH - - M ko:K06330 - ko00000 Spore Coat
NMMECHGA_01199 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NMMECHGA_01200 1.02e-74 yisL - - S - - - UPF0344 protein
NMMECHGA_01201 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NMMECHGA_01202 4.29e-131 yisN - - S - - - Protein of unknown function (DUF2777)
NMMECHGA_01203 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NMMECHGA_01204 4.95e-145 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
NMMECHGA_01205 2.91e-310 yisQ - - V - - - Mate efflux family protein
NMMECHGA_01206 1.41e-207 yisR - - K - - - Transcriptional regulator
NMMECHGA_01207 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NMMECHGA_01208 7.04e-247 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
NMMECHGA_01209 9.94e-120 yisT - - S - - - DinB family
NMMECHGA_01210 2.03e-135 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
NMMECHGA_01211 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMMECHGA_01212 5.04e-95 yisX - - S - - - Pentapeptide repeats (9 copies)
NMMECHGA_01213 4.53e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NMMECHGA_01214 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NMMECHGA_01215 5.14e-291 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
NMMECHGA_01216 3.19e-183 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
NMMECHGA_01217 1.96e-155 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
NMMECHGA_01218 7.15e-179 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
NMMECHGA_01219 6.62e-140 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NMMECHGA_01220 5.04e-282 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NMMECHGA_01221 4.1e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NMMECHGA_01222 4.19e-202 yitH - - K - - - Acetyltransferase (GNAT) domain
NMMECHGA_01223 6.19e-93 - - - S - - - Acetyltransferase (GNAT) domain
NMMECHGA_01224 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NMMECHGA_01225 1.75e-76 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
NMMECHGA_01226 3.08e-201 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
NMMECHGA_01227 4.16e-122 - - - - - - - -
NMMECHGA_01228 2.02e-218 - - - - - - - -
NMMECHGA_01229 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
NMMECHGA_01230 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
NMMECHGA_01231 8.68e-120 - - - - - - - -
NMMECHGA_01232 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
NMMECHGA_01233 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
NMMECHGA_01234 9.13e-202 yitS - - S - - - protein conserved in bacteria
NMMECHGA_01235 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NMMECHGA_01236 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
NMMECHGA_01237 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
NMMECHGA_01238 1.92e-08 - - - - - - - -
NMMECHGA_01239 5.29e-199 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NMMECHGA_01240 7.18e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NMMECHGA_01241 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
NMMECHGA_01242 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
NMMECHGA_01243 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
NMMECHGA_01244 1.32e-113 yitZ - - G - - - Major Facilitator Superfamily
NMMECHGA_01245 1.43e-252 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NMMECHGA_01246 5.83e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NMMECHGA_01247 1.27e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NMMECHGA_01248 1.14e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
NMMECHGA_01249 3.86e-261 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NMMECHGA_01250 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
NMMECHGA_01251 2.47e-224 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NMMECHGA_01252 2.51e-39 yjzC - - S - - - YjzC-like protein
NMMECHGA_01253 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
NMMECHGA_01254 4.88e-182 yjaU - - I - - - carboxylic ester hydrolase activity
NMMECHGA_01255 6.08e-131 yjaV - - - - - - -
NMMECHGA_01256 3.7e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
NMMECHGA_01257 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
NMMECHGA_01258 2.67e-38 yjzB - - - - - - -
NMMECHGA_01259 4.6e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMMECHGA_01260 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NMMECHGA_01261 4.51e-191 yjaZ - - O - - - Zn-dependent protease
NMMECHGA_01262 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NMMECHGA_01263 5.69e-235 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NMMECHGA_01264 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
NMMECHGA_01265 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMMECHGA_01266 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMMECHGA_01267 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
NMMECHGA_01268 2.06e-233 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
NMMECHGA_01269 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NMMECHGA_01270 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMMECHGA_01271 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMMECHGA_01272 1.37e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NMMECHGA_01273 1.27e-219 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NMMECHGA_01274 7.68e-246 yjbB - - EGP - - - Major Facilitator Superfamily
NMMECHGA_01275 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMMECHGA_01276 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NMMECHGA_01277 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
NMMECHGA_01278 6.89e-151 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NMMECHGA_01279 1.41e-278 coiA - - S ko:K06198 - ko00000 Competence protein
NMMECHGA_01280 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NMMECHGA_01281 2.68e-28 - - - - - - - -
NMMECHGA_01283 6.27e-217 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NMMECHGA_01284 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
NMMECHGA_01285 1.46e-128 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NMMECHGA_01286 7.32e-130 yjbK - - S - - - protein conserved in bacteria
NMMECHGA_01287 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
NMMECHGA_01288 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
NMMECHGA_01289 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NMMECHGA_01290 1.23e-201 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NMMECHGA_01291 3.3e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NMMECHGA_01292 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NMMECHGA_01293 2.32e-176 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NMMECHGA_01294 5.47e-137 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
NMMECHGA_01295 1.27e-274 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
NMMECHGA_01296 8.9e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
NMMECHGA_01297 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NMMECHGA_01298 5.08e-237 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NMMECHGA_01299 1.39e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NMMECHGA_01300 5.03e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NMMECHGA_01301 6.3e-105 yjbX - - S - - - Spore coat protein
NMMECHGA_01302 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
NMMECHGA_01303 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
NMMECHGA_01304 3.55e-110 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
NMMECHGA_01305 2.34e-51 cotW - - - ko:K06341 - ko00000 -
NMMECHGA_01306 1.44e-72 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
NMMECHGA_01307 5.03e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
NMMECHGA_01310 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
NMMECHGA_01311 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NMMECHGA_01312 2.12e-49 - - - - - - - -
NMMECHGA_01313 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMMECHGA_01314 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
NMMECHGA_01315 3.04e-174 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
NMMECHGA_01316 8.05e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NMMECHGA_01317 2.61e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NMMECHGA_01318 1.68e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
NMMECHGA_01319 4.09e-271 yjcL - - S - - - Protein of unknown function (DUF819)
NMMECHGA_01322 1.33e-50 - - - - - - - -
NMMECHGA_01324 1.75e-297 - - - M - - - nucleic acid phosphodiester bond hydrolysis
NMMECHGA_01328 6.67e-216 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NMMECHGA_01329 1.27e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
NMMECHGA_01330 7.25e-60 yjcN - - - - - - -
NMMECHGA_01331 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
NMMECHGA_01332 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NMMECHGA_01333 8.45e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NMMECHGA_01334 1.2e-71 yjdF3 - - S - - - Protein of unknown function (DUF2992)
NMMECHGA_01335 1.26e-117 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NMMECHGA_01337 1.13e-102 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NMMECHGA_01338 2.5e-39 - - - S - - - Domain of unknown function (DUF4177)
NMMECHGA_01339 2.22e-67 yjdJ - - S - - - Domain of unknown function (DUF4306)
NMMECHGA_01340 5.31e-224 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NMMECHGA_01342 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
NMMECHGA_01343 6.11e-106 - - - S - - - Protein of unknown function (DUF2690)
NMMECHGA_01344 1.13e-29 yjfB - - S - - - Putative motility protein
NMMECHGA_01345 9.97e-214 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
NMMECHGA_01346 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
NMMECHGA_01347 4.96e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
NMMECHGA_01348 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
NMMECHGA_01349 3.61e-119 yjgD - - S - - - Protein of unknown function (DUF1641)
NMMECHGA_01351 8.73e-146 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NMMECHGA_01353 3.89e-285 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NMMECHGA_01354 1.69e-277 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NMMECHGA_01355 1.11e-41 - - - - - - - -
NMMECHGA_01356 5.15e-179 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NMMECHGA_01357 1.5e-154 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
NMMECHGA_01358 6.58e-174 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NMMECHGA_01359 5.79e-117 yjlB - - S - - - Cupin domain
NMMECHGA_01360 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
NMMECHGA_01361 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NMMECHGA_01362 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
NMMECHGA_01363 2.5e-313 - - - G ko:K03292 - ko00000 symporter YjmB
NMMECHGA_01364 5.72e-239 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
NMMECHGA_01365 7.59e-245 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
NMMECHGA_01366 1.6e-272 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
NMMECHGA_01367 1.34e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NMMECHGA_01368 7.93e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
NMMECHGA_01369 4.02e-237 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
NMMECHGA_01370 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
NMMECHGA_01371 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
NMMECHGA_01372 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
NMMECHGA_01373 2.71e-103 yjoA - - S - - - DinB family
NMMECHGA_01374 2.48e-313 VCP - - O - - - AAA domain (dynein-related subfamily)
NMMECHGA_01375 1.42e-270 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NMMECHGA_01377 1.04e-54 - - - S - - - YCII-related domain
NMMECHGA_01378 9.23e-219 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NMMECHGA_01379 6.43e-79 yjqA - - S - - - Bacterial PH domain
NMMECHGA_01380 9.94e-142 yjqB - - S - - - Pfam:DUF867
NMMECHGA_01381 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
NMMECHGA_01382 7.3e-143 xkdA - - E - - - IrrE N-terminal-like domain
NMMECHGA_01383 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
NMMECHGA_01385 3.07e-202 xkdB - - K - - - sequence-specific DNA binding
NMMECHGA_01386 7.48e-153 xkdC - - L - - - Bacterial dnaA protein
NMMECHGA_01390 2.33e-109 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NMMECHGA_01391 3.93e-178 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
NMMECHGA_01392 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
NMMECHGA_01393 0.0 yqbA - - S - - - portal protein
NMMECHGA_01394 1.99e-176 xkdF3 - - L - - - Putative phage serine protease XkdF
NMMECHGA_01395 1.12e-216 xkdG - - S - - - Phage capsid family
NMMECHGA_01396 1.63e-82 yqbG - - S - - - Protein of unknown function (DUF3199)
NMMECHGA_01397 4.29e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
NMMECHGA_01398 4.62e-112 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
NMMECHGA_01399 2.27e-98 xkdJ - - - - - - -
NMMECHGA_01400 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
NMMECHGA_01401 6.01e-99 xkdM - - S - - - Phage tail tube protein
NMMECHGA_01402 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
NMMECHGA_01403 0.0 xkdO - - L - - - Transglycosylase SLT domain
NMMECHGA_01404 1.48e-152 xkdP - - S - - - Lysin motif
NMMECHGA_01405 2.31e-232 xkdQ - - G - - - NLP P60 protein
NMMECHGA_01406 1.24e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
NMMECHGA_01407 1.33e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
NMMECHGA_01408 4.2e-242 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NMMECHGA_01409 5.35e-133 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
NMMECHGA_01410 4.43e-56 - - - - - - - -
NMMECHGA_01411 2.88e-221 - - - - - - - -
NMMECHGA_01412 6.09e-58 xkdW - - S - - - XkdW protein
NMMECHGA_01413 6.35e-31 xkdX - - - - - - -
NMMECHGA_01414 4.34e-198 xepA - - - - - - -
NMMECHGA_01415 7.71e-52 xhlA - - S - - - Haemolysin XhlA
NMMECHGA_01416 8.12e-53 xhlB - - S - - - SPP1 phage holin
NMMECHGA_01417 5.76e-212 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
NMMECHGA_01418 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
NMMECHGA_01419 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
NMMECHGA_01420 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
NMMECHGA_01421 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
NMMECHGA_01422 3.66e-309 steT - - E ko:K03294 - ko00000 amino acid
NMMECHGA_01423 2.82e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NMMECHGA_01425 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NMMECHGA_01426 7.41e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NMMECHGA_01428 8.43e-285 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMMECHGA_01429 7.85e-177 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
NMMECHGA_01430 1.63e-195 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
NMMECHGA_01431 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMMECHGA_01432 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMMECHGA_01433 1.57e-235 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NMMECHGA_01434 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NMMECHGA_01436 5.33e-222 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
NMMECHGA_01437 4.64e-255 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NMMECHGA_01438 8.84e-211 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NMMECHGA_01439 8.44e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NMMECHGA_01440 8.08e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
NMMECHGA_01441 8.45e-204 ykgA - - E - - - Amidinotransferase
NMMECHGA_01442 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
NMMECHGA_01443 5.35e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NMMECHGA_01444 1.15e-13 - - - - - - - -
NMMECHGA_01445 3.25e-166 ykjA - - S - - - Protein of unknown function (DUF421)
NMMECHGA_01446 3.57e-125 ykkA - - S - - - Protein of unknown function (DUF664)
NMMECHGA_01447 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NMMECHGA_01448 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
NMMECHGA_01449 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
NMMECHGA_01450 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NMMECHGA_01451 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NMMECHGA_01452 1.6e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NMMECHGA_01453 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
NMMECHGA_01454 2.86e-97 ohrR - - K - - - COG1846 Transcriptional regulators
NMMECHGA_01455 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
NMMECHGA_01456 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
NMMECHGA_01457 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NMMECHGA_01458 8.62e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NMMECHGA_01459 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NMMECHGA_01460 8.95e-174 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NMMECHGA_01461 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_01462 5.67e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NMMECHGA_01463 2.97e-143 ykoF - - S - - - YKOF-related Family
NMMECHGA_01464 1.23e-158 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMMECHGA_01465 2.46e-306 ykoH - - T - - - Histidine kinase
NMMECHGA_01466 6.47e-144 ykoI - - S - - - Peptidase propeptide and YPEB domain
NMMECHGA_01467 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
NMMECHGA_01468 1.45e-08 - - - - - - - -
NMMECHGA_01470 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
NMMECHGA_01471 1.49e-70 tnrA - - K - - - transcriptional
NMMECHGA_01472 1.63e-25 - - - - - - - -
NMMECHGA_01473 3.04e-36 ykoL - - - - - - -
NMMECHGA_01474 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
NMMECHGA_01475 7.71e-278 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NMMECHGA_01476 2.48e-129 ykoP - - G - - - polysaccharide deacetylase
NMMECHGA_01477 1.77e-197 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
NMMECHGA_01478 0.0 ykoS - - - - - - -
NMMECHGA_01479 2.72e-237 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
NMMECHGA_01480 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
NMMECHGA_01481 1.25e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NMMECHGA_01482 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
NMMECHGA_01483 2.83e-142 ykoX - - S - - - membrane-associated protein
NMMECHGA_01484 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NMMECHGA_01485 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMMECHGA_01486 2.33e-198 rsgI - - S - - - Anti-sigma factor N-terminus
NMMECHGA_01487 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
NMMECHGA_01488 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
NMMECHGA_01489 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NMMECHGA_01490 2.58e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
NMMECHGA_01492 1.77e-28 ykzE - - - - - - -
NMMECHGA_01493 5.54e-243 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
NMMECHGA_01494 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMMECHGA_01495 2.27e-114 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NMMECHGA_01497 3.12e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NMMECHGA_01498 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NMMECHGA_01499 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NMMECHGA_01500 6.56e-294 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NMMECHGA_01501 7.99e-294 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NMMECHGA_01502 7.2e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NMMECHGA_01503 1.51e-145 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NMMECHGA_01504 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NMMECHGA_01505 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
NMMECHGA_01507 5.62e-93 eag - - - - - - -
NMMECHGA_01508 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NMMECHGA_01509 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
NMMECHGA_01510 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NMMECHGA_01511 1.65e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NMMECHGA_01512 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
NMMECHGA_01513 7.06e-229 ykvI - - S - - - membrane
NMMECHGA_01514 2.61e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NMMECHGA_01515 5.72e-104 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
NMMECHGA_01516 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NMMECHGA_01517 1.37e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NMMECHGA_01518 3.53e-81 ykvN - - K - - - Transcriptional regulator
NMMECHGA_01519 1.89e-172 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NMMECHGA_01520 1.74e-271 - - - M - - - Glycosyl transferases group 1
NMMECHGA_01521 7.56e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
NMMECHGA_01522 7.12e-204 - - - G - - - Glycosyl hydrolases family 18
NMMECHGA_01523 2.67e-62 ykvR - - S - - - Protein of unknown function (DUF3219)
NMMECHGA_01524 5.43e-35 ykvS - - S - - - protein conserved in bacteria
NMMECHGA_01525 2.6e-39 - - - - - - - -
NMMECHGA_01526 5.26e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
NMMECHGA_01527 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMMECHGA_01528 5.79e-117 stoA - - CO - - - thiol-disulfide
NMMECHGA_01529 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NMMECHGA_01530 3.99e-09 - - - - - - - -
NMMECHGA_01531 2.25e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NMMECHGA_01532 2.21e-228 ykvZ - - K - - - Transcriptional regulator
NMMECHGA_01533 2.79e-167 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
NMMECHGA_01534 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NMMECHGA_01535 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
NMMECHGA_01536 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NMMECHGA_01537 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_01538 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
NMMECHGA_01539 4.2e-160 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMMECHGA_01540 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NMMECHGA_01541 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NMMECHGA_01542 4.4e-171 ykwD - - J - - - protein with SCP PR1 domains
NMMECHGA_01543 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NMMECHGA_01544 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMMECHGA_01545 5.95e-283 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NMMECHGA_01546 1.05e-22 - - - - - - - -
NMMECHGA_01547 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
NMMECHGA_01548 2.15e-109 ykyB - - S - - - YkyB-like protein
NMMECHGA_01549 2.55e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NMMECHGA_01550 5.84e-115 ykuD - - S - - - protein conserved in bacteria
NMMECHGA_01551 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
NMMECHGA_01552 1.83e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMMECHGA_01553 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
NMMECHGA_01554 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
NMMECHGA_01555 2.62e-121 - - - S ko:K09776 - ko00000 Ribonuclease H-like
NMMECHGA_01556 7.83e-38 ykzF - - S - - - Antirepressor AbbA
NMMECHGA_01557 5.15e-100 ykuL - - S - - - CBS domain
NMMECHGA_01558 6.52e-216 ccpC - - K - - - Transcriptional regulator
NMMECHGA_01559 1.44e-109 - - - C ko:K03839 - ko00000 Flavodoxin domain
NMMECHGA_01560 1.23e-222 ykuO - - - - - - -
NMMECHGA_01561 2.95e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
NMMECHGA_01562 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NMMECHGA_01563 8.95e-273 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NMMECHGA_01564 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
NMMECHGA_01565 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
NMMECHGA_01566 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
NMMECHGA_01567 1.21e-103 ykuV - - CO - - - thiol-disulfide
NMMECHGA_01568 4.71e-122 rok - - K - - - Repressor of ComK
NMMECHGA_01569 1.64e-198 yknT - - - ko:K06437 - ko00000 -
NMMECHGA_01570 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NMMECHGA_01571 1.26e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NMMECHGA_01572 2.9e-311 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
NMMECHGA_01573 8.11e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
NMMECHGA_01574 3.83e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
NMMECHGA_01575 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NMMECHGA_01576 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NMMECHGA_01577 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NMMECHGA_01578 1.86e-150 yknW - - S - - - Yip1 domain
NMMECHGA_01579 5.75e-234 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NMMECHGA_01580 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_01581 4.52e-264 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NMMECHGA_01582 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_01583 4.07e-215 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
NMMECHGA_01584 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NMMECHGA_01585 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NMMECHGA_01586 5.43e-52 ykoA - - - - - - -
NMMECHGA_01587 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NMMECHGA_01588 5.78e-215 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NMMECHGA_01589 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
NMMECHGA_01590 1.09e-18 - - - S - - - Uncharacterized protein YkpC
NMMECHGA_01591 2.51e-233 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
NMMECHGA_01592 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
NMMECHGA_01593 2.65e-306 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NMMECHGA_01594 2.93e-199 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
NMMECHGA_01595 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NMMECHGA_01596 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NMMECHGA_01597 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMMECHGA_01598 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
NMMECHGA_01599 6.8e-186 ykrA - - S - - - hydrolases of the HAD superfamily
NMMECHGA_01600 2.29e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NMMECHGA_01601 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NMMECHGA_01602 3.24e-147 ykyA - - L - - - Putative cell-wall binding lipoprotein
NMMECHGA_01603 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NMMECHGA_01604 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NMMECHGA_01605 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMMECHGA_01606 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NMMECHGA_01607 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
NMMECHGA_01608 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
NMMECHGA_01609 1.56e-55 yktA - - S - - - Belongs to the UPF0223 family
NMMECHGA_01610 5.28e-152 yktB - - S - - - Belongs to the UPF0637 family
NMMECHGA_01611 4.48e-35 ykzI - - - - - - -
NMMECHGA_01612 1.57e-193 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
NMMECHGA_01613 4.07e-98 ykzC - - S - - - Acetyltransferase (GNAT) family
NMMECHGA_01614 1.01e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NMMECHGA_01615 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
NMMECHGA_01616 0.0 ylaA - - - - - - -
NMMECHGA_01617 1.44e-56 ylaB - - - - - - -
NMMECHGA_01618 2.51e-115 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NMMECHGA_01620 5.7e-56 ylaE - - - - - - -
NMMECHGA_01621 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
NMMECHGA_01622 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NMMECHGA_01623 4.4e-63 ylaH - - S - - - YlaH-like protein
NMMECHGA_01624 3.64e-43 ylaI - - S - - - protein conserved in bacteria
NMMECHGA_01625 9.93e-126 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NMMECHGA_01626 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
NMMECHGA_01627 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NMMECHGA_01628 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NMMECHGA_01629 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
NMMECHGA_01630 7.05e-271 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NMMECHGA_01631 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NMMECHGA_01632 2.34e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NMMECHGA_01633 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NMMECHGA_01634 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NMMECHGA_01635 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NMMECHGA_01636 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NMMECHGA_01637 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NMMECHGA_01638 1.48e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
NMMECHGA_01639 1.61e-81 ylbA - - S - - - YugN-like family
NMMECHGA_01640 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
NMMECHGA_01641 2.54e-255 ylbC - - S - - - protein with SCP PR1 domains
NMMECHGA_01642 6.28e-87 ylbD - - S - - - Putative coat protein
NMMECHGA_01643 1.73e-48 ylbE - - S - - - YlbE-like protein
NMMECHGA_01644 1.36e-96 ylbF - - S - - - Belongs to the UPF0342 family
NMMECHGA_01645 4.36e-52 ylbG - - S - - - UPF0298 protein
NMMECHGA_01646 1.13e-121 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
NMMECHGA_01647 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NMMECHGA_01648 1.06e-279 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
NMMECHGA_01649 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NMMECHGA_01650 4.34e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NMMECHGA_01651 6.13e-18 yqgA - - - - - - -
NMMECHGA_01652 6.24e-152 ylbM - - S - - - Belongs to the UPF0348 family
NMMECHGA_01654 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
NMMECHGA_01655 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NMMECHGA_01656 1.35e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NMMECHGA_01657 1.33e-115 ylbP - - K - - - n-acetyltransferase
NMMECHGA_01658 3.22e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NMMECHGA_01659 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NMMECHGA_01660 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NMMECHGA_01661 4.76e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NMMECHGA_01662 3.42e-68 ftsL - - D - - - Essential cell division protein
NMMECHGA_01663 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NMMECHGA_01664 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
NMMECHGA_01665 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NMMECHGA_01666 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NMMECHGA_01667 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NMMECHGA_01668 5.45e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NMMECHGA_01669 3.15e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NMMECHGA_01670 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
NMMECHGA_01671 2.77e-177 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NMMECHGA_01672 1.35e-143 ylxW - - S - - - protein conserved in bacteria
NMMECHGA_01673 1.06e-132 ylxX - - S - - - protein conserved in bacteria
NMMECHGA_01674 5.37e-76 sbp - - S - - - small basic protein
NMMECHGA_01675 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NMMECHGA_01676 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NMMECHGA_01677 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
NMMECHGA_01678 2.49e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NMMECHGA_01679 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMMECHGA_01680 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMMECHGA_01681 1.1e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NMMECHGA_01682 7.81e-316 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
NMMECHGA_01683 3.58e-51 ylmC - - S - - - sporulation protein
NMMECHGA_01684 1.12e-204 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
NMMECHGA_01685 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NMMECHGA_01686 4.47e-87 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NMMECHGA_01687 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
NMMECHGA_01688 1.23e-177 ylmH - - S - - - conserved protein, contains S4-like domain
NMMECHGA_01689 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
NMMECHGA_01690 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NMMECHGA_01691 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
NMMECHGA_01692 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NMMECHGA_01693 8.3e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NMMECHGA_01694 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NMMECHGA_01695 1.3e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
NMMECHGA_01696 4.4e-215 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NMMECHGA_01697 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NMMECHGA_01698 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NMMECHGA_01699 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
NMMECHGA_01700 1.5e-182 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NMMECHGA_01701 2.11e-221 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NMMECHGA_01702 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NMMECHGA_01703 2.57e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NMMECHGA_01705 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
NMMECHGA_01706 1.04e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
NMMECHGA_01707 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
NMMECHGA_01708 1.59e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NMMECHGA_01709 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NMMECHGA_01710 1.39e-185 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
NMMECHGA_01711 4.6e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
NMMECHGA_01712 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
NMMECHGA_01713 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
NMMECHGA_01714 8.41e-202 yloC - - S - - - stress-induced protein
NMMECHGA_01715 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
NMMECHGA_01716 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NMMECHGA_01717 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NMMECHGA_01718 1.03e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NMMECHGA_01719 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NMMECHGA_01720 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NMMECHGA_01721 1.49e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NMMECHGA_01722 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NMMECHGA_01723 2.07e-261 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NMMECHGA_01724 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NMMECHGA_01725 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NMMECHGA_01726 2.27e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NMMECHGA_01727 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NMMECHGA_01728 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NMMECHGA_01729 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NMMECHGA_01730 3.65e-78 yloU - - S - - - protein conserved in bacteria
NMMECHGA_01731 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
NMMECHGA_01732 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NMMECHGA_01733 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NMMECHGA_01734 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NMMECHGA_01735 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NMMECHGA_01736 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NMMECHGA_01737 3.09e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NMMECHGA_01738 2.03e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NMMECHGA_01739 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NMMECHGA_01740 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NMMECHGA_01741 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NMMECHGA_01742 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NMMECHGA_01743 1.67e-114 - - - - - - - -
NMMECHGA_01744 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NMMECHGA_01745 1.96e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NMMECHGA_01746 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NMMECHGA_01747 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NMMECHGA_01748 5.66e-79 ylqD - - S - - - YlqD protein
NMMECHGA_01749 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NMMECHGA_01750 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NMMECHGA_01751 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NMMECHGA_01752 1.15e-199 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NMMECHGA_01753 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMMECHGA_01754 0.0 ylqG - - - - - - -
NMMECHGA_01755 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
NMMECHGA_01756 1.94e-268 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NMMECHGA_01757 3.09e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NMMECHGA_01758 3.62e-215 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
NMMECHGA_01759 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NMMECHGA_01760 9.03e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NMMECHGA_01761 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
NMMECHGA_01762 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NMMECHGA_01763 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NMMECHGA_01764 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NMMECHGA_01765 3.27e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NMMECHGA_01766 2.16e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
NMMECHGA_01767 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
NMMECHGA_01768 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
NMMECHGA_01769 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NMMECHGA_01770 6.4e-143 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
NMMECHGA_01771 1.74e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NMMECHGA_01772 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
NMMECHGA_01773 2.93e-83 ylxF - - S - - - MgtE intracellular N domain
NMMECHGA_01774 1.58e-305 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
NMMECHGA_01775 4.67e-95 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
NMMECHGA_01776 1.42e-175 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
NMMECHGA_01777 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
NMMECHGA_01778 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NMMECHGA_01779 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NMMECHGA_01780 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
NMMECHGA_01781 1.25e-133 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
NMMECHGA_01782 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
NMMECHGA_01783 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
NMMECHGA_01784 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
NMMECHGA_01785 7.85e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NMMECHGA_01786 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NMMECHGA_01787 3.81e-254 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
NMMECHGA_01788 2.12e-198 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
NMMECHGA_01789 2.58e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NMMECHGA_01790 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
NMMECHGA_01791 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
NMMECHGA_01792 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NMMECHGA_01793 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NMMECHGA_01794 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMMECHGA_01795 9.41e-99 ylxL - - - - - - -
NMMECHGA_01796 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NMMECHGA_01797 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NMMECHGA_01798 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NMMECHGA_01799 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NMMECHGA_01800 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NMMECHGA_01801 1.65e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NMMECHGA_01802 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NMMECHGA_01803 9.72e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NMMECHGA_01804 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NMMECHGA_01805 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMMECHGA_01806 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NMMECHGA_01807 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NMMECHGA_01808 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
NMMECHGA_01809 6.16e-63 ylxQ - - J - - - ribosomal protein
NMMECHGA_01810 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NMMECHGA_01811 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
NMMECHGA_01812 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NMMECHGA_01813 3.49e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NMMECHGA_01814 3.84e-231 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NMMECHGA_01815 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NMMECHGA_01816 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NMMECHGA_01817 6.89e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
NMMECHGA_01818 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
NMMECHGA_01819 1.53e-56 ymxH - - S - - - YlmC YmxH family
NMMECHGA_01820 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
NMMECHGA_01821 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NMMECHGA_01822 1.66e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NMMECHGA_01823 4.03e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NMMECHGA_01824 2.6e-200 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NMMECHGA_01825 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMMECHGA_01826 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
NMMECHGA_01827 4.94e-44 - - - S - - - YlzJ-like protein
NMMECHGA_01828 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NMMECHGA_01829 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_01830 2.08e-267 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NMMECHGA_01831 1.1e-297 albE - - S - - - Peptidase M16
NMMECHGA_01832 1.08e-305 ymfH - - S - - - zinc protease
NMMECHGA_01833 7.38e-167 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NMMECHGA_01834 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
NMMECHGA_01835 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
NMMECHGA_01836 8.75e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
NMMECHGA_01837 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NMMECHGA_01838 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NMMECHGA_01839 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NMMECHGA_01840 9.43e-279 pbpX - - V - - - Beta-lactamase
NMMECHGA_01841 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NMMECHGA_01842 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
NMMECHGA_01843 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
NMMECHGA_01844 1.18e-252 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NMMECHGA_01845 5.89e-278 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NMMECHGA_01846 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NMMECHGA_01847 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
NMMECHGA_01848 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
NMMECHGA_01849 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NMMECHGA_01850 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NMMECHGA_01851 2.93e-92 - - - S - - - Regulatory protein YrvL
NMMECHGA_01853 3.24e-126 ymcC - - S - - - Membrane
NMMECHGA_01854 2.94e-141 pksA - - K - - - Transcriptional regulator
NMMECHGA_01855 1.64e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
NMMECHGA_01856 1.31e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NMMECHGA_01857 1.35e-235 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
NMMECHGA_01858 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NMMECHGA_01859 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
NMMECHGA_01860 2.42e-300 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NMMECHGA_01861 5.61e-313 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
NMMECHGA_01862 2.78e-181 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
NMMECHGA_01863 3.67e-175 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
NMMECHGA_01864 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NMMECHGA_01865 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NMMECHGA_01866 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NMMECHGA_01867 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NMMECHGA_01868 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
NMMECHGA_01869 3.39e-295 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NMMECHGA_01870 8.03e-81 ymzB - - - - - - -
NMMECHGA_01871 6.29e-206 - - - S - - - Metallo-beta-lactamase superfamily
NMMECHGA_01872 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
NMMECHGA_01874 1.61e-162 ymaC - - S - - - Replication protein
NMMECHGA_01875 5.98e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
NMMECHGA_01876 6.39e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
NMMECHGA_01877 1.94e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NMMECHGA_01879 5.41e-76 ymaF - - S - - - YmaF family
NMMECHGA_01880 3.24e-222 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NMMECHGA_01881 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NMMECHGA_01882 1.63e-31 - - - - - - - -
NMMECHGA_01883 1.2e-30 ymzA - - - - - - -
NMMECHGA_01884 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
NMMECHGA_01885 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMMECHGA_01886 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMMECHGA_01887 2.24e-141 - - - - - - - -
NMMECHGA_01888 1.64e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NMMECHGA_01889 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
NMMECHGA_01890 1.05e-292 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NMMECHGA_01891 3.93e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NMMECHGA_01892 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
NMMECHGA_01893 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NMMECHGA_01894 4.16e-170 int - - L - - - Belongs to the 'phage' integrase family
NMMECHGA_01895 6.02e-55 - - - E - - - Zn peptidase
NMMECHGA_01896 1.14e-33 - - - K - - - Helix-turn-helix XRE-family like proteins
NMMECHGA_01899 9.02e-105 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
NMMECHGA_01902 3.3e-129 - - - L - - - DnaD domain protein
NMMECHGA_01903 8.57e-19 - - - S - - - Loader and inhibitor of phage G40P
NMMECHGA_01904 9.37e-212 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 replicative DNA helicase
NMMECHGA_01905 5.34e-31 - - - - - - - -
NMMECHGA_01906 4.28e-12 - - - S - - - Phage-like element PBSX protein XtrA
NMMECHGA_01908 1.93e-66 - - - M - - - ArpU family transcriptional regulator
NMMECHGA_01914 1.04e-35 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
NMMECHGA_01917 2.4e-66 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
NMMECHGA_01918 7.37e-102 - - - L - - - phage terminase small subunit
NMMECHGA_01919 0.0 - - - S - - - Terminase
NMMECHGA_01920 2.24e-219 - - - S - - - Phage portal protein
NMMECHGA_01921 8.8e-101 - - - S - - - peptidase activity
NMMECHGA_01922 7.86e-204 - - - S - - - capsid protein
NMMECHGA_01923 1.29e-35 - - - - - - - -
NMMECHGA_01924 9.84e-51 - - - S - - - Phage gp6-like head-tail connector protein
NMMECHGA_01925 1.06e-51 - - - S - - - Phage head-tail joining protein
NMMECHGA_01926 1.39e-65 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NMMECHGA_01928 1.17e-101 - - - N - - - Phage major tail protein phi13
NMMECHGA_01931 0.0 - - - D - - - phage tail tape measure protein
NMMECHGA_01932 5.34e-132 - - - S - - - Phage tail protein
NMMECHGA_01933 3.46e-271 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
NMMECHGA_01934 1.05e-59 - - - - - - - -
NMMECHGA_01937 5.94e-77 - - - S - - - Domain of unknown function (DUF2479)
NMMECHGA_01940 2.18e-75 - - - S - - - Bacteriophage holin family
NMMECHGA_01941 1.78e-161 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NMMECHGA_01942 1.29e-66 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NMMECHGA_01943 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NMMECHGA_01944 4.2e-134 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NMMECHGA_01947 8.9e-13 - - - - - - - -
NMMECHGA_01948 1.12e-38 - - - - - - - -
NMMECHGA_01949 6.87e-50 - - - - - - - -
NMMECHGA_01950 2.05e-116 - - - G - - - SMI1-KNR4 cell-wall
NMMECHGA_01951 8.63e-181 ynaC - - - - - - -
NMMECHGA_01952 6.49e-16 - - - S - - - Protein of unknown function (DUF1433)
NMMECHGA_01953 7.11e-127 ynaD - - J - - - Acetyltransferase (GNAT) domain
NMMECHGA_01955 8.61e-96 - - - S - - - CAAX protease self-immunity
NMMECHGA_01958 4.15e-108 - - - E - - - phosphoribosylanthranilate isomerase activity
NMMECHGA_01959 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
NMMECHGA_01960 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NMMECHGA_01961 4.29e-276 xylR - - GK - - - ROK family
NMMECHGA_01962 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
NMMECHGA_01963 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
NMMECHGA_01964 5.06e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
NMMECHGA_01965 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NMMECHGA_01966 1.02e-279 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NMMECHGA_01968 1.29e-105 - - - S - - - Protein of unknown function (DUF2691)
NMMECHGA_01969 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
NMMECHGA_01970 7.54e-22 - - - - - - - -
NMMECHGA_01973 1.86e-208 - - - S - - - Thymidylate synthase
NMMECHGA_01975 9.21e-153 - - - S - - - Domain of unknown function, YrpD
NMMECHGA_01978 2.78e-33 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
NMMECHGA_01979 7.34e-95 - - - - - - - -
NMMECHGA_01980 5.19e-103 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
NMMECHGA_01984 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NMMECHGA_01985 1.08e-247 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
NMMECHGA_01986 3.17e-279 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
NMMECHGA_01987 4.88e-194 yndG - - S - - - DoxX-like family
NMMECHGA_01988 2.34e-147 - - - S - - - Domain of unknown function (DUF4166)
NMMECHGA_01989 0.0 yndJ - - S - - - YndJ-like protein
NMMECHGA_01991 9.34e-175 yndL - - S - - - Replication protein
NMMECHGA_01992 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
NMMECHGA_01993 1.43e-100 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NMMECHGA_01994 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NMMECHGA_01995 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NMMECHGA_01996 3.65e-141 yneB - - L - - - resolvase
NMMECHGA_01997 4.7e-43 ynzC - - S - - - UPF0291 protein
NMMECHGA_01998 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NMMECHGA_01999 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
NMMECHGA_02000 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
NMMECHGA_02001 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
NMMECHGA_02002 1.38e-163 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
NMMECHGA_02003 8.62e-77 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
NMMECHGA_02004 3.57e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
NMMECHGA_02005 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
NMMECHGA_02006 1.66e-84 cotM - - O ko:K06335 - ko00000 Spore coat protein
NMMECHGA_02007 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
NMMECHGA_02008 3.27e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
NMMECHGA_02009 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NMMECHGA_02010 8.47e-117 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NMMECHGA_02011 2.33e-09 - - - S - - - Fur-regulated basic protein B
NMMECHGA_02013 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
NMMECHGA_02014 4.02e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
NMMECHGA_02015 4.68e-71 yneQ - - - - - - -
NMMECHGA_02016 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
NMMECHGA_02017 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NMMECHGA_02018 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
NMMECHGA_02019 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NMMECHGA_02020 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NMMECHGA_02021 1.82e-18 - - - - - - - -
NMMECHGA_02022 1.06e-75 ynfC - - - - - - -
NMMECHGA_02023 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NMMECHGA_02024 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
NMMECHGA_02026 1.97e-316 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
NMMECHGA_02027 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NMMECHGA_02028 1.17e-101 yngA - - S - - - membrane
NMMECHGA_02029 4.54e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NMMECHGA_02030 2.01e-134 yngC - - S - - - membrane-associated protein
NMMECHGA_02031 4.28e-295 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
NMMECHGA_02032 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NMMECHGA_02033 4.75e-172 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
NMMECHGA_02034 6.73e-212 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
NMMECHGA_02035 2.4e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
NMMECHGA_02036 9.36e-317 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
NMMECHGA_02037 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NMMECHGA_02038 1.47e-265 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NMMECHGA_02039 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
NMMECHGA_02040 1.01e-82 yngL - - S - - - Protein of unknown function (DUF1360)
NMMECHGA_02041 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
NMMECHGA_02042 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMMECHGA_02043 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMMECHGA_02044 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMMECHGA_02045 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMMECHGA_02046 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NMMECHGA_02047 6.18e-237 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NMMECHGA_02048 9.8e-313 yoeA - - V - - - MATE efflux family protein
NMMECHGA_02049 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
NMMECHGA_02051 1.14e-124 - - - L - - - Integrase
NMMECHGA_02052 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
NMMECHGA_02053 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NMMECHGA_02054 9.8e-198 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_02055 5.46e-233 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NMMECHGA_02056 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NMMECHGA_02057 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
NMMECHGA_02058 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_02059 2.33e-262 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NMMECHGA_02060 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMMECHGA_02061 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NMMECHGA_02062 1.87e-158 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NMMECHGA_02063 9.43e-52 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
NMMECHGA_02064 2.11e-173 yoxB - - - - - - -
NMMECHGA_02065 2.57e-62 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NMMECHGA_02066 3.04e-298 yoaB - - EGP - - - the major facilitator superfamily
NMMECHGA_02067 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
NMMECHGA_02068 1.37e-233 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMMECHGA_02069 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NMMECHGA_02070 2.08e-44 yoaF - - - - - - -
NMMECHGA_02072 1.71e-18 - - - - - - - -
NMMECHGA_02073 1.13e-59 - - - S - - - Protein of unknown function (DUF4025)
NMMECHGA_02074 2.65e-309 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
NMMECHGA_02075 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
NMMECHGA_02076 3.71e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
NMMECHGA_02077 1.79e-145 yoaK - - S - - - Membrane
NMMECHGA_02078 3.38e-251 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
NMMECHGA_02079 4.69e-167 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
NMMECHGA_02082 2.08e-269 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NMMECHGA_02085 2.45e-109 - - - - - - - -
NMMECHGA_02086 1.04e-217 yoaR - - V - - - vancomycin resistance protein
NMMECHGA_02087 4.58e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
NMMECHGA_02088 7.19e-41 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_02089 2.71e-189 yoaT - - S - - - Protein of unknown function (DUF817)
NMMECHGA_02090 3.17e-201 yoaU - - K - - - LysR substrate binding domain
NMMECHGA_02091 2.5e-199 yoaV - - EG - - - EamA-like transporter family
NMMECHGA_02092 1.18e-79 yoaW - - - - - - -
NMMECHGA_02093 5.94e-148 lin0465 - - S - - - DJ-1/PfpI family
NMMECHGA_02094 2.34e-211 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
NMMECHGA_02097 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
NMMECHGA_02098 1.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
NMMECHGA_02099 1.47e-16 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
NMMECHGA_02106 1.47e-150 - - - - - - - -
NMMECHGA_02108 1.22e-81 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
NMMECHGA_02109 1.48e-30 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
NMMECHGA_02110 2.07e-13 - - - S - - - YolD-like protein
NMMECHGA_02111 5.78e-55 - - - - - - - -
NMMECHGA_02114 9.14e-110 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NMMECHGA_02115 1.53e-81 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NMMECHGA_02116 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
NMMECHGA_02117 9e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
NMMECHGA_02118 1.23e-173 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
NMMECHGA_02119 6.15e-182 - - - J - - - FR47-like protein
NMMECHGA_02120 9.22e-129 yobS - - K - - - Transcriptional regulator
NMMECHGA_02121 7.76e-169 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NMMECHGA_02122 1.13e-107 - - - K - - - Bacterial transcription activator, effector binding domain
NMMECHGA_02123 3.5e-221 yobV - - K - - - WYL domain
NMMECHGA_02124 1.74e-119 yobW - - - - - - -
NMMECHGA_02125 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
NMMECHGA_02126 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NMMECHGA_02127 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
NMMECHGA_02128 2.79e-180 - - - - - - - -
NMMECHGA_02129 2.99e-119 yocC - - - - - - -
NMMECHGA_02130 6.44e-239 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
NMMECHGA_02131 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
NMMECHGA_02132 3.51e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMMECHGA_02133 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMMECHGA_02134 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
NMMECHGA_02135 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NMMECHGA_02136 4.18e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NMMECHGA_02137 1.42e-107 yocK - - T - - - general stress protein
NMMECHGA_02138 3.02e-70 yocL - - - - - - -
NMMECHGA_02139 5.79e-43 - - - - - - - -
NMMECHGA_02140 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NMMECHGA_02141 2.94e-55 yozN - - - - - - -
NMMECHGA_02142 1.83e-49 yocN - - - - - - -
NMMECHGA_02143 2.17e-74 yozO - - S - - - Bacterial PH domain
NMMECHGA_02144 1.91e-42 yozC - - - - - - -
NMMECHGA_02145 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NMMECHGA_02146 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
NMMECHGA_02147 3.91e-211 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
NMMECHGA_02148 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NMMECHGA_02149 9.48e-214 yocS - - S ko:K03453 - ko00000 -transporter
NMMECHGA_02150 5.23e-264 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NMMECHGA_02151 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NMMECHGA_02152 0.0 yojO - - P - - - Von Willebrand factor
NMMECHGA_02153 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
NMMECHGA_02154 6.01e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NMMECHGA_02155 2.62e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NMMECHGA_02156 3.12e-291 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
NMMECHGA_02157 3.69e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NMMECHGA_02159 9.78e-312 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
NMMECHGA_02160 2.49e-194 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NMMECHGA_02161 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
NMMECHGA_02162 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
NMMECHGA_02163 1.85e-58 - - - - - - - -
NMMECHGA_02164 8.13e-208 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
NMMECHGA_02165 7.43e-107 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
NMMECHGA_02166 1.95e-14 - - - - - - - -
NMMECHGA_02167 1.08e-288 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
NMMECHGA_02168 5.64e-84 iolK - - S - - - tautomerase
NMMECHGA_02169 2.63e-73 yodB - - K - - - transcriptional
NMMECHGA_02170 1.92e-140 yodC - - C - - - nitroreductase
NMMECHGA_02171 3.61e-144 yahD - - S ko:K06999 - ko00000 Carboxylesterase
NMMECHGA_02172 9.3e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NMMECHGA_02173 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
NMMECHGA_02174 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMMECHGA_02175 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NMMECHGA_02176 3.69e-167 yodH - - Q - - - Methyltransferase
NMMECHGA_02177 4.86e-41 yodI - - - - - - -
NMMECHGA_02178 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NMMECHGA_02179 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
NMMECHGA_02180 2.08e-12 - - - - - - - -
NMMECHGA_02181 1.17e-71 yodL - - S - - - YodL-like
NMMECHGA_02182 4.69e-137 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NMMECHGA_02183 5.18e-34 yozD - - S - - - YozD-like protein
NMMECHGA_02185 7.44e-159 yodN - - - - - - -
NMMECHGA_02186 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
NMMECHGA_02187 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
NMMECHGA_02188 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
NMMECHGA_02189 1.51e-196 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
NMMECHGA_02190 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
NMMECHGA_02191 2.41e-151 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NMMECHGA_02192 1.55e-157 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NMMECHGA_02193 1.91e-314 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NMMECHGA_02195 7.71e-182 yiiD - - K ko:K06323 - ko00000 acetyltransferase
NMMECHGA_02196 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
NMMECHGA_02197 1.06e-59 cgeC - - - ko:K06321 - ko00000 -
NMMECHGA_02198 3.1e-83 cgeA - - - ko:K06319 - ko00000 -
NMMECHGA_02199 8.99e-226 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
NMMECHGA_02200 2.31e-279 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
NMMECHGA_02201 2.83e-82 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NMMECHGA_02203 1.87e-115 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NMMECHGA_02214 6.02e-43 - - - - - - - -
NMMECHGA_02216 1.86e-206 - - - S - - - Calcineurin-like phosphoesterase
NMMECHGA_02217 7.52e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
NMMECHGA_02219 2.02e-75 - - - - - - - -
NMMECHGA_02221 5.97e-205 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NMMECHGA_02224 5.3e-22 - - - - - - - -
NMMECHGA_02225 7.63e-100 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
NMMECHGA_02227 2.65e-48 - - - O - - - Glutaredoxin
NMMECHGA_02228 2.42e-236 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMMECHGA_02230 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMMECHGA_02231 6.76e-37 - - - S - - - NrdI Flavodoxin like
NMMECHGA_02236 8.8e-16 - - - S - - - YopX protein
NMMECHGA_02243 4.49e-27 - - - S - - - Calcineurin-like phosphoesterase
NMMECHGA_02249 1.38e-77 - 2.1.1.37 - L ko:K17398 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NMMECHGA_02252 1.25e-102 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
NMMECHGA_02255 6.62e-28 - - - S - - - protein conserved in bacteria
NMMECHGA_02256 0.0 - - - L - - - DNA polymerase elongation subunit (Family B)
NMMECHGA_02257 5.1e-214 - - - S - - - PD-(D/E)XK nuclease superfamily
NMMECHGA_02258 6.85e-193 - - - L - - - DNA primase activity
NMMECHGA_02259 3.58e-304 - - - L - - - DnaB-like helicase C terminal domain
NMMECHGA_02261 1.39e-199 - - - S - - - AAA domain
NMMECHGA_02262 1.18e-223 - - - - - - - -
NMMECHGA_02266 3.43e-87 - - - K - - - SIR2-like domain
NMMECHGA_02268 3.43e-163 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
NMMECHGA_02269 4.13e-187 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
NMMECHGA_02278 5.05e-121 - - - S - - - Protein of unknown function (DUF1273)
NMMECHGA_02281 4.33e-89 yoqH - - M - - - LysM domain
NMMECHGA_02290 2.05e-311 - - - - - - - -
NMMECHGA_02297 7.23e-84 - - - - - - - -
NMMECHGA_02299 1.23e-43 yoaF - - - - - - -
NMMECHGA_02300 9.79e-84 - - - S - - - SEFIR domain
NMMECHGA_02305 1.76e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NMMECHGA_02309 2.36e-42 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NMMECHGA_02310 4.98e-106 yoaW - - - - - - -
NMMECHGA_02311 4.48e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NMMECHGA_02312 1.59e-05 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Metallopeptidase family M24
NMMECHGA_02314 5.64e-24 - - - - - - - -
NMMECHGA_02319 6.85e-295 - - - S - - - DNA replication origin binding
NMMECHGA_02321 1.52e-62 - - - - - - - -
NMMECHGA_02324 0.0 - - - - - - - -
NMMECHGA_02325 3.47e-54 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NMMECHGA_02328 2.98e-271 - - - S - - - Calcineurin-like phosphoesterase superfamily domain
NMMECHGA_02331 4.45e-225 - - - - - - - -
NMMECHGA_02332 0.0 - - - S - - - Terminase-like family
NMMECHGA_02333 0.0 - - - - - - - -
NMMECHGA_02334 0.0 - - - - - - - -
NMMECHGA_02335 1.02e-121 - - - - - - - -
NMMECHGA_02336 3.43e-236 - - - - - - - -
NMMECHGA_02337 7.73e-104 - - - - - - - -
NMMECHGA_02338 1.22e-88 - - - - - - - -
NMMECHGA_02340 5.49e-156 - - - - - - - -
NMMECHGA_02341 3.16e-102 - - - - - - - -
NMMECHGA_02342 3.62e-114 - - - - - - - -
NMMECHGA_02343 6.41e-75 - - - - - - - -
NMMECHGA_02346 1.9e-70 - - - - - - - -
NMMECHGA_02347 6.64e-34 - - - - - - - -
NMMECHGA_02350 5.61e-71 - - - - - - - -
NMMECHGA_02351 1.24e-85 - - - - - - - -
NMMECHGA_02352 6.29e-154 - - - L - - - Belongs to the 'phage' integrase family
NMMECHGA_02356 2.28e-149 - - - - - - - -
NMMECHGA_02357 0.0 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NMMECHGA_02358 7.98e-112 - - - S - - - Phage tail protein
NMMECHGA_02359 0.0 - - - S - - - Pfam Transposase IS66
NMMECHGA_02360 6.68e-143 - - - - - - - -
NMMECHGA_02361 2.12e-55 - - - S - - - virus tail, fiber
NMMECHGA_02362 3.47e-246 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
NMMECHGA_02364 2.39e-50 - - - S - - - Bacteriophage holin
NMMECHGA_02365 9.15e-131 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NMMECHGA_02367 4.31e-54 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NMMECHGA_02369 1.49e-32 - 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
NMMECHGA_02370 5.66e-17 - - - Q - - - methyltransferase
NMMECHGA_02372 1.76e-298 - - - S - - - damaged DNA binding
NMMECHGA_02373 1.75e-69 - - - S - - - YolD-like protein
NMMECHGA_02374 1.27e-58 - - - - - - - -
NMMECHGA_02378 4.67e-122 - - - J - - - Acetyltransferase (GNAT) domain
NMMECHGA_02379 3.29e-120 yokK - - S - - - SMI1 / KNR4 family
NMMECHGA_02380 4.52e-101 - - - S - - - SMI1-KNR4 cell-wall
NMMECHGA_02381 1.78e-219 - - - S - - - Bacterial EndoU nuclease
NMMECHGA_02382 3.86e-79 - - - G - - - SMI1-KNR4 cell-wall
NMMECHGA_02383 2.8e-21 - - - - - - - -
NMMECHGA_02384 3.63e-167 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
NMMECHGA_02385 3e-103 - - - S - - - Bacterial PH domain
NMMECHGA_02386 1.08e-78 - - - S - - - DNase/tRNase domain of colicin-like bacteriocin
NMMECHGA_02387 3.64e-88 - - - S - - - SMI1 / KNR4 family
NMMECHGA_02389 1.07e-302 yokA - - L - - - Recombinase
NMMECHGA_02390 1.76e-124 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NMMECHGA_02391 2.04e-102 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NMMECHGA_02392 2.82e-132 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NMMECHGA_02393 4.14e-94 ypoP - - K - - - transcriptional
NMMECHGA_02394 1.16e-288 mepA - - V - - - MATE efflux family protein
NMMECHGA_02395 2.13e-40 ypmT - - S - - - Uncharacterized ympT
NMMECHGA_02396 7.94e-128 ypmS - - S - - - protein conserved in bacteria
NMMECHGA_02397 1.37e-173 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
NMMECHGA_02398 2.1e-135 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NMMECHGA_02399 1.05e-53 ypmP - - S - - - Protein of unknown function (DUF2535)
NMMECHGA_02400 4.07e-307 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NMMECHGA_02401 3.85e-234 yplP - - K - - - Transcriptional regulator
NMMECHGA_02402 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
NMMECHGA_02403 6.68e-143 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NMMECHGA_02404 4.56e-120 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NMMECHGA_02405 3.19e-197 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NMMECHGA_02406 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
NMMECHGA_02407 3.33e-146 ypjP - - S - - - YpjP-like protein
NMMECHGA_02408 2.81e-183 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
NMMECHGA_02409 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
NMMECHGA_02410 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
NMMECHGA_02411 2e-204 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
NMMECHGA_02412 7.77e-137 yagB - - S ko:K06950 - ko00000 phosphohydrolase
NMMECHGA_02413 6.08e-112 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
NMMECHGA_02414 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NMMECHGA_02416 5.22e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NMMECHGA_02417 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
NMMECHGA_02418 1.17e-22 degR - - - - - - -
NMMECHGA_02419 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
NMMECHGA_02420 7.99e-41 ypeQ - - S - - - Zinc-finger
NMMECHGA_02421 1.56e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
NMMECHGA_02422 6.59e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NMMECHGA_02423 1.27e-86 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
NMMECHGA_02424 2.59e-05 - - - - ko:K06429 - ko00000 -
NMMECHGA_02425 2.26e-213 ypcP - - L - - - 5'3' exonuclease
NMMECHGA_02426 1.08e-11 - - - - - - - -
NMMECHGA_02427 1.66e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
NMMECHGA_02428 0.0 ypbR - - S - - - Dynamin family
NMMECHGA_02429 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
NMMECHGA_02430 4.18e-262 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
NMMECHGA_02431 2.47e-291 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
NMMECHGA_02432 8.16e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NMMECHGA_02433 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NMMECHGA_02434 2.02e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NMMECHGA_02435 3.45e-131 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
NMMECHGA_02436 1.64e-236 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
NMMECHGA_02437 7.8e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
NMMECHGA_02438 1.03e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NMMECHGA_02439 1.96e-177 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMMECHGA_02440 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
NMMECHGA_02442 8.14e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NMMECHGA_02443 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NMMECHGA_02444 8.38e-129 ypsA - - S - - - Belongs to the UPF0398 family
NMMECHGA_02445 3.43e-299 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
NMMECHGA_02446 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NMMECHGA_02447 5.3e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
NMMECHGA_02448 1.24e-94 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NMMECHGA_02449 1.45e-66 yppG - - S - - - YppG-like protein
NMMECHGA_02450 9.21e-11 - - - S - - - YppF-like protein
NMMECHGA_02451 1.01e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
NMMECHGA_02454 6.19e-239 yppC - - S - - - Protein of unknown function (DUF2515)
NMMECHGA_02455 1.07e-148 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NMMECHGA_02456 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NMMECHGA_02457 1.43e-121 ypoC - - - - - - -
NMMECHGA_02458 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NMMECHGA_02459 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
NMMECHGA_02460 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
NMMECHGA_02461 5.1e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NMMECHGA_02462 2.66e-102 ypmB - - S - - - protein conserved in bacteria
NMMECHGA_02463 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
NMMECHGA_02464 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NMMECHGA_02465 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NMMECHGA_02466 3.03e-197 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NMMECHGA_02467 1.14e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NMMECHGA_02468 1.98e-233 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NMMECHGA_02469 5.25e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NMMECHGA_02470 6.72e-265 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
NMMECHGA_02471 7.71e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
NMMECHGA_02472 1.03e-92 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
NMMECHGA_02473 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NMMECHGA_02474 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
NMMECHGA_02475 2.49e-198 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NMMECHGA_02476 2.79e-182 ypjB - - S - - - sporulation protein
NMMECHGA_02477 1.15e-125 ypjA - - S - - - membrane
NMMECHGA_02478 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
NMMECHGA_02479 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
NMMECHGA_02480 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
NMMECHGA_02481 1.12e-99 ypiF - - S - - - Protein of unknown function (DUF2487)
NMMECHGA_02482 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
NMMECHGA_02483 1.76e-297 ypiA - - S - - - COG0457 FOG TPR repeat
NMMECHGA_02484 7.8e-299 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NMMECHGA_02485 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
NMMECHGA_02486 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NMMECHGA_02487 1.56e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NMMECHGA_02488 4.44e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NMMECHGA_02489 6.39e-150 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
NMMECHGA_02490 1.7e-144 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NMMECHGA_02491 5.83e-228 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NMMECHGA_02492 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NMMECHGA_02493 8.08e-83 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NMMECHGA_02494 3.31e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NMMECHGA_02495 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NMMECHGA_02496 1.23e-181 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
NMMECHGA_02497 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NMMECHGA_02498 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NMMECHGA_02499 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NMMECHGA_02500 5.05e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NMMECHGA_02501 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NMMECHGA_02502 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
NMMECHGA_02503 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NMMECHGA_02504 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NMMECHGA_02505 6.13e-176 yphF - - - - - - -
NMMECHGA_02506 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
NMMECHGA_02507 8.97e-231 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NMMECHGA_02508 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NMMECHGA_02509 8.69e-40 ypzH - - - - - - -
NMMECHGA_02510 8.78e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
NMMECHGA_02511 7.82e-134 yphA - - - - - - -
NMMECHGA_02512 1.13e-11 - - - S - - - YpzI-like protein
NMMECHGA_02513 1.14e-235 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NMMECHGA_02514 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NMMECHGA_02515 2.36e-145 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NMMECHGA_02516 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
NMMECHGA_02517 8.95e-142 ypfA - - M - - - Flagellar protein YcgR
NMMECHGA_02518 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
NMMECHGA_02519 2.82e-207 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
NMMECHGA_02520 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
NMMECHGA_02521 5.29e-224 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
NMMECHGA_02522 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NMMECHGA_02523 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NMMECHGA_02524 5.05e-187 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
NMMECHGA_02525 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
NMMECHGA_02526 8.61e-143 ypbE - - M - - - Lysin motif
NMMECHGA_02527 2.05e-127 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
NMMECHGA_02528 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NMMECHGA_02529 4.28e-253 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
NMMECHGA_02530 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
NMMECHGA_02531 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NMMECHGA_02532 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMMECHGA_02533 7.62e-171 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NMMECHGA_02534 4.1e-252 rsiX - - - - - - -
NMMECHGA_02535 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NMMECHGA_02536 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMMECHGA_02537 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMMECHGA_02538 6.36e-277 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NMMECHGA_02539 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
NMMECHGA_02540 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NMMECHGA_02541 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NMMECHGA_02542 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
NMMECHGA_02543 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
NMMECHGA_02544 1.18e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NMMECHGA_02545 6.13e-128 ypuI - - S - - - Protein of unknown function (DUF3907)
NMMECHGA_02546 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NMMECHGA_02547 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NMMECHGA_02548 4.17e-119 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
NMMECHGA_02549 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMMECHGA_02550 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NMMECHGA_02551 1.27e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NMMECHGA_02552 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NMMECHGA_02553 2.93e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NMMECHGA_02554 5.98e-72 ypuD - - - - - - -
NMMECHGA_02555 1.18e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NMMECHGA_02556 1.28e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
NMMECHGA_02557 2.12e-17 - - - S - - - SNARE associated Golgi protein
NMMECHGA_02560 2.61e-34 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMMECHGA_02565 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMMECHGA_02566 3.12e-192 ypuA - - S - - - Secreted protein
NMMECHGA_02567 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NMMECHGA_02568 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
NMMECHGA_02569 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
NMMECHGA_02570 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
NMMECHGA_02571 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
NMMECHGA_02572 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
NMMECHGA_02573 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
NMMECHGA_02574 1.35e-142 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
NMMECHGA_02575 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMMECHGA_02576 1.37e-99 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NMMECHGA_02577 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
NMMECHGA_02578 7.93e-270 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NMMECHGA_02579 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NMMECHGA_02580 6.8e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NMMECHGA_02581 3.91e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
NMMECHGA_02582 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
NMMECHGA_02583 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NMMECHGA_02584 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NMMECHGA_02585 7.27e-42 yqkK - - - - - - -
NMMECHGA_02586 6.27e-306 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NMMECHGA_02587 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NMMECHGA_02588 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
NMMECHGA_02589 2.07e-237 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
NMMECHGA_02590 3.18e-77 ansR - - K - - - Transcriptional regulator
NMMECHGA_02591 4.16e-280 yqxK - - L - - - DNA helicase
NMMECHGA_02592 1.17e-119 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
NMMECHGA_02593 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
NMMECHGA_02594 8.88e-216 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
NMMECHGA_02595 4.65e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
NMMECHGA_02596 1.38e-223 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NMMECHGA_02597 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
NMMECHGA_02598 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
NMMECHGA_02599 1.08e-246 yqkA - - K - - - GrpB protein
NMMECHGA_02600 1.52e-76 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
NMMECHGA_02601 2.22e-112 yqjY - - K ko:K06977 - ko00000 acetyltransferase
NMMECHGA_02602 1.87e-65 yqiX - - S - - - YolD-like protein
NMMECHGA_02603 4.7e-303 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMMECHGA_02605 4.23e-287 yqjV - - G - - - Major Facilitator Superfamily
NMMECHGA_02607 2.21e-94 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMMECHGA_02608 2.69e-228 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NMMECHGA_02609 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
NMMECHGA_02610 6.89e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NMMECHGA_02611 1.56e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NMMECHGA_02612 1.96e-189 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMMECHGA_02613 0.0 rocB - - E - - - arginine degradation protein
NMMECHGA_02614 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NMMECHGA_02615 3.17e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NMMECHGA_02616 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NMMECHGA_02617 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NMMECHGA_02618 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NMMECHGA_02619 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NMMECHGA_02620 9.1e-300 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMMECHGA_02621 1.77e-32 yqzJ - - - - - - -
NMMECHGA_02622 1.37e-183 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NMMECHGA_02623 1.57e-177 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
NMMECHGA_02624 1.06e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
NMMECHGA_02625 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NMMECHGA_02626 1.56e-93 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
NMMECHGA_02628 4.87e-128 yqjB - - S - - - protein conserved in bacteria
NMMECHGA_02629 1.73e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
NMMECHGA_02630 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NMMECHGA_02631 2.1e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NMMECHGA_02632 1.37e-173 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NMMECHGA_02633 7.65e-101 yqiW - - S - - - Belongs to the UPF0403 family
NMMECHGA_02634 4.23e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NMMECHGA_02635 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NMMECHGA_02636 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
NMMECHGA_02637 3.77e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMMECHGA_02638 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NMMECHGA_02639 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NMMECHGA_02640 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NMMECHGA_02641 3.39e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
NMMECHGA_02642 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NMMECHGA_02643 3.02e-199 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
NMMECHGA_02644 0.0 bkdR - - KT - - - Transcriptional regulator
NMMECHGA_02645 9.02e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
NMMECHGA_02646 4e-205 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NMMECHGA_02647 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
NMMECHGA_02648 3.07e-263 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NMMECHGA_02649 8.19e-267 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
NMMECHGA_02650 1.33e-196 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
NMMECHGA_02651 5.46e-279 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NMMECHGA_02652 3.39e-168 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NMMECHGA_02653 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
NMMECHGA_02654 4.74e-37 - - - - - - - -
NMMECHGA_02655 1.15e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NMMECHGA_02657 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NMMECHGA_02658 5.12e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
NMMECHGA_02659 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NMMECHGA_02660 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NMMECHGA_02661 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
NMMECHGA_02662 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NMMECHGA_02663 8.48e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NMMECHGA_02664 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NMMECHGA_02665 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NMMECHGA_02666 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NMMECHGA_02667 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NMMECHGA_02668 1.65e-88 yqhY - - S - - - protein conserved in bacteria
NMMECHGA_02669 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NMMECHGA_02670 1.25e-90 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NMMECHGA_02671 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
NMMECHGA_02672 1.08e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
NMMECHGA_02673 2.58e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
NMMECHGA_02674 4.42e-256 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
NMMECHGA_02675 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
NMMECHGA_02676 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
NMMECHGA_02677 5.69e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
NMMECHGA_02678 1e-217 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
NMMECHGA_02679 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
NMMECHGA_02680 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NMMECHGA_02681 2.46e-248 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NMMECHGA_02682 5.55e-100 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
NMMECHGA_02683 3.27e-120 yqhR - - S - - - Conserved membrane protein YqhR
NMMECHGA_02684 1.73e-219 yqhQ - - S - - - Protein of unknown function (DUF1385)
NMMECHGA_02685 5.18e-81 yqhP - - - - - - -
NMMECHGA_02686 1.41e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NMMECHGA_02687 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NMMECHGA_02688 9.17e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NMMECHGA_02689 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
NMMECHGA_02690 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NMMECHGA_02691 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NMMECHGA_02692 8.13e-263 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
NMMECHGA_02693 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NMMECHGA_02694 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
NMMECHGA_02695 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
NMMECHGA_02696 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
NMMECHGA_02697 3.67e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
NMMECHGA_02698 1e-95 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
NMMECHGA_02699 1.14e-155 yqxM - - - ko:K19433 - ko00000 -
NMMECHGA_02700 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
NMMECHGA_02701 2.84e-36 yqzE - - S - - - YqzE-like protein
NMMECHGA_02702 3.78e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
NMMECHGA_02703 4.1e-60 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
NMMECHGA_02704 1.77e-78 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
NMMECHGA_02705 9.32e-92 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
NMMECHGA_02706 1.53e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
NMMECHGA_02707 2.39e-216 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
NMMECHGA_02708 1.28e-256 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NMMECHGA_02709 8.73e-233 yqxL - - P - - - Mg2 transporter protein
NMMECHGA_02710 5.77e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NMMECHGA_02711 2.79e-189 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NMMECHGA_02713 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
NMMECHGA_02714 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
NMMECHGA_02715 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
NMMECHGA_02716 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
NMMECHGA_02717 7.34e-66 yqgV - - S - - - Thiamine-binding protein
NMMECHGA_02718 1.89e-256 yqgU - - - - - - -
NMMECHGA_02719 5.89e-281 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
NMMECHGA_02720 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NMMECHGA_02721 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NMMECHGA_02722 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
NMMECHGA_02723 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
NMMECHGA_02724 3.38e-14 yqgO - - - - - - -
NMMECHGA_02725 3.13e-134 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NMMECHGA_02726 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NMMECHGA_02727 2.64e-253 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
NMMECHGA_02729 2.81e-67 yqzD - - - - - - -
NMMECHGA_02730 1.19e-97 yqzC - - S - - - YceG-like family
NMMECHGA_02731 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NMMECHGA_02732 2.8e-189 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NMMECHGA_02733 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
NMMECHGA_02734 1.43e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NMMECHGA_02735 4.51e-206 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NMMECHGA_02736 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
NMMECHGA_02737 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
NMMECHGA_02738 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
NMMECHGA_02739 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
NMMECHGA_02740 2.74e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
NMMECHGA_02741 2.84e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
NMMECHGA_02742 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NMMECHGA_02743 2.04e-81 yqfX - - S - - - membrane
NMMECHGA_02744 1.37e-140 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
NMMECHGA_02745 2.47e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
NMMECHGA_02746 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NMMECHGA_02747 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
NMMECHGA_02748 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NMMECHGA_02749 1.09e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NMMECHGA_02750 5.96e-50 yqfQ - - S - - - YqfQ-like protein
NMMECHGA_02751 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NMMECHGA_02752 5.35e-269 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NMMECHGA_02753 1.14e-148 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NMMECHGA_02754 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NMMECHGA_02755 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NMMECHGA_02756 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NMMECHGA_02757 4.96e-113 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
NMMECHGA_02758 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NMMECHGA_02759 3.29e-144 ccpN - - K - - - CBS domain
NMMECHGA_02760 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NMMECHGA_02761 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NMMECHGA_02762 1.24e-185 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NMMECHGA_02763 5.29e-27 - - - S - - - YqzL-like protein
NMMECHGA_02764 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NMMECHGA_02765 2.73e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NMMECHGA_02766 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NMMECHGA_02767 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NMMECHGA_02768 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
NMMECHGA_02770 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
NMMECHGA_02771 2.1e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
NMMECHGA_02772 2.07e-60 yqfC - - S - - - sporulation protein YqfC
NMMECHGA_02773 4.27e-77 yqfB - - - - - - -
NMMECHGA_02774 4.35e-192 yqfA - - S - - - UPF0365 protein
NMMECHGA_02775 7.97e-292 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
NMMECHGA_02776 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
NMMECHGA_02777 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NMMECHGA_02778 1.4e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
NMMECHGA_02779 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
NMMECHGA_02780 1.38e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NMMECHGA_02781 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
NMMECHGA_02782 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NMMECHGA_02783 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NMMECHGA_02784 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NMMECHGA_02785 9.53e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NMMECHGA_02786 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NMMECHGA_02787 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NMMECHGA_02788 2.88e-69 yqxA - - S - - - Protein of unknown function (DUF3679)
NMMECHGA_02789 2.24e-282 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
NMMECHGA_02790 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NMMECHGA_02791 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NMMECHGA_02792 2.35e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NMMECHGA_02793 2.36e-22 - - - S - - - YqzM-like protein
NMMECHGA_02794 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NMMECHGA_02795 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NMMECHGA_02796 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
NMMECHGA_02797 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMMECHGA_02798 9.8e-179 yqeM - - Q - - - Methyltransferase
NMMECHGA_02799 6.61e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NMMECHGA_02800 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
NMMECHGA_02801 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NMMECHGA_02802 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
NMMECHGA_02803 2.32e-198 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NMMECHGA_02804 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NMMECHGA_02805 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
NMMECHGA_02807 6.41e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
NMMECHGA_02808 9.74e-176 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
NMMECHGA_02809 1.81e-132 yqeD - - S - - - SNARE associated Golgi protein
NMMECHGA_02810 4.23e-214 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
NMMECHGA_02811 7.4e-168 - - - - - - - -
NMMECHGA_02812 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
NMMECHGA_02813 7.53e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMMECHGA_02814 1.43e-44 - - - L ko:K06400 - ko00000 Recombinase
NMMECHGA_02815 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NMMECHGA_02816 1.14e-197 yybE - - K - - - Transcriptional regulator
NMMECHGA_02817 5.99e-201 ydhE - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
NMMECHGA_02818 2.97e-92 - 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
NMMECHGA_02819 3.04e-264 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major Facilitator Superfamily
NMMECHGA_02820 3.07e-96 - - - P ko:K03449 - ko00000,ko02000 transporter
NMMECHGA_02821 1.62e-196 - 1.8.5.5 - C ko:K08352 ko00920,ko01120,map00920,map01120 ko00000,ko00001,ko01000,ko02000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NMMECHGA_02822 9.18e-77 - - - S - - - Flavodoxin-like fold
NMMECHGA_02823 2.17e-99 yvbU - - K - - - Transcriptional regulator
NMMECHGA_02824 3.69e-223 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
NMMECHGA_02827 3.56e-259 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
NMMECHGA_02829 1e-81 - - - - - - - -
NMMECHGA_02830 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
NMMECHGA_02832 5.52e-37 - - - S - - - SMI1-KNR4 cell-wall
NMMECHGA_02833 2.19e-20 - - - S - - - SMI1 / KNR4 family
NMMECHGA_02834 5.47e-62 - - - - - - - -
NMMECHGA_02835 1.2e-39 - - - - - - - -
NMMECHGA_02837 1.78e-155 - - - EGP - - - Necrosis inducing protein (NPP1)
NMMECHGA_02839 9.86e-200 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
NMMECHGA_02840 1.06e-117 - - - K - - - Transcriptional regulator PadR-like family
NMMECHGA_02841 3.82e-229 yjlA - - EG - - - Putative multidrug resistance efflux transporter
NMMECHGA_02842 5.98e-144 - - - K - - - COG1802 Transcriptional regulators
NMMECHGA_02843 5.03e-163 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
NMMECHGA_02844 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
NMMECHGA_02845 5.78e-270 yrkH - - P - - - Rhodanese Homology Domain
NMMECHGA_02846 0.000436 perX - - S - - - DsrE/DsrF-like family
NMMECHGA_02847 2.28e-126 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
NMMECHGA_02848 2.67e-106 yrkE - - O - - - DsrE/DsrF/DrsH-like family
NMMECHGA_02849 4.38e-52 yrkD - - S - - - protein conserved in bacteria
NMMECHGA_02850 2.12e-136 yrkC - - G - - - Cupin domain
NMMECHGA_02851 1.39e-191 bltR - - K - - - helix_turn_helix, mercury resistance
NMMECHGA_02852 1.31e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NMMECHGA_02853 2.52e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
NMMECHGA_02854 1.69e-296 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NMMECHGA_02855 2.45e-23 - - - S - - - YrzO-like protein
NMMECHGA_02856 1.03e-217 yrdR - - EG - - - EamA-like transporter family
NMMECHGA_02857 3.3e-202 - - - K - - - Transcriptional regulator
NMMECHGA_02858 4.29e-254 trkA - - P ko:K07222 - ko00000 Oxidoreductase
NMMECHGA_02859 8.83e-214 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
NMMECHGA_02860 2.39e-85 yodA - - S - - - tautomerase
NMMECHGA_02861 9.9e-208 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
NMMECHGA_02862 3.17e-16 - - - C - - - Oxidoreductase molybdopterin binding domain
NMMECHGA_02863 1.49e-293 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NMMECHGA_02864 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
NMMECHGA_02865 2.2e-174 azlC - - E - - - AzlC protein
NMMECHGA_02866 4.13e-104 bkdR - - K - - - helix_turn_helix ASNC type
NMMECHGA_02867 2.73e-33 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
NMMECHGA_02868 5.74e-283 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NMMECHGA_02869 9.24e-27 - - - K - - - Acetyltransferase (GNAT) family
NMMECHGA_02870 3.49e-82 - - - K - - - Transcriptional regulator
NMMECHGA_02871 1.28e-208 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
NMMECHGA_02872 9.69e-291 msmE - - G ko:K10120 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NMMECHGA_02873 6.56e-189 - - - P ko:K02025,ko:K10121 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NMMECHGA_02874 5.29e-180 - - - P ko:K02026,ko:K10122 - ko00000,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
NMMECHGA_02875 7.3e-256 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
NMMECHGA_02876 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NMMECHGA_02877 7.09e-187 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
NMMECHGA_02878 5.5e-98 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NMMECHGA_02879 0.000176 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NMMECHGA_02880 2.11e-130 yrdC - - Q - - - Isochorismatase family
NMMECHGA_02881 8.93e-73 - - - S - - - Protein of unknown function (DUF2568)
NMMECHGA_02882 1.42e-118 yrdA - - S - - - DinB family
NMMECHGA_02883 4.94e-211 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
NMMECHGA_02884 4.23e-246 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NMMECHGA_02885 9.38e-186 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NMMECHGA_02887 1.14e-160 yrpD - - S - - - Domain of unknown function, YrpD
NMMECHGA_02888 4.48e-127 - - - S - - - Flavin reductase like domain
NMMECHGA_02889 4.56e-156 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
NMMECHGA_02890 6e-65 - - - S - - - YjbR
NMMECHGA_02891 9.03e-30 epsA - - I - - - Passenger-associated-transport-repeat
NMMECHGA_02892 2.55e-167 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NMMECHGA_02893 1.69e-119 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NMMECHGA_02894 5.72e-238 yrpG - - C - - - Aldo/keto reductase family
NMMECHGA_02895 5.73e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NMMECHGA_02896 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMMECHGA_02897 2.72e-197 - - - S - - - Alpha beta hydrolase
NMMECHGA_02898 1.9e-79 - - - T - - - sh3 domain protein
NMMECHGA_02899 5.9e-81 - - - T - - - sh3 domain protein
NMMECHGA_02900 3.69e-84 - - - E - - - Glyoxalase-like domain
NMMECHGA_02901 1.2e-49 yraG - - - ko:K06440 - ko00000 -
NMMECHGA_02902 9.61e-84 yraF - - M - - - Spore coat protein
NMMECHGA_02903 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NMMECHGA_02904 6.11e-36 yraE - - - ko:K06440 - ko00000 -
NMMECHGA_02905 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
NMMECHGA_02906 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
NMMECHGA_02907 1.11e-33 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
NMMECHGA_02908 1.61e-251 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
NMMECHGA_02909 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NMMECHGA_02910 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NMMECHGA_02911 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NMMECHGA_02912 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NMMECHGA_02913 4.41e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
NMMECHGA_02914 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NMMECHGA_02915 0.0 levR - - K - - - PTS system fructose IIA component
NMMECHGA_02916 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NMMECHGA_02917 4.63e-136 yrhP - - E - - - LysE type translocator
NMMECHGA_02918 8.04e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
NMMECHGA_02919 9.97e-114 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NMMECHGA_02920 7.09e-191 rsiV - - S - - - Protein of unknown function (DUF3298)
NMMECHGA_02921 0.0 oatA - - I - - - Acyltransferase family
NMMECHGA_02922 3.02e-57 yrhK - - S - - - YrhK-like protein
NMMECHGA_02923 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NMMECHGA_02924 9.22e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
NMMECHGA_02925 1.01e-122 yrhH - - Q - - - methyltransferase
NMMECHGA_02926 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
NMMECHGA_02928 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
NMMECHGA_02930 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
NMMECHGA_02931 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
NMMECHGA_02932 1.73e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
NMMECHGA_02933 6.93e-49 yrhC - - S - - - YrhC-like protein
NMMECHGA_02934 8.19e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NMMECHGA_02935 4.07e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
NMMECHGA_02936 3.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NMMECHGA_02937 9.86e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
NMMECHGA_02938 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
NMMECHGA_02939 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
NMMECHGA_02940 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
NMMECHGA_02941 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NMMECHGA_02942 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NMMECHGA_02943 9.33e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
NMMECHGA_02944 3.64e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
NMMECHGA_02945 3.29e-153 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
NMMECHGA_02946 1.77e-240 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NMMECHGA_02947 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
NMMECHGA_02948 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NMMECHGA_02949 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
NMMECHGA_02950 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NMMECHGA_02951 3.07e-242 yrrI - - S - - - AI-2E family transporter
NMMECHGA_02952 1.28e-167 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NMMECHGA_02953 8.63e-186 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NMMECHGA_02954 3.24e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NMMECHGA_02955 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NMMECHGA_02956 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
NMMECHGA_02957 8.4e-42 yrzR - - - - - - -
NMMECHGA_02958 3.39e-106 yrrD - - S - - - protein conserved in bacteria
NMMECHGA_02959 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NMMECHGA_02960 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
NMMECHGA_02961 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NMMECHGA_02962 3.11e-271 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NMMECHGA_02963 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_02964 4.71e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NMMECHGA_02965 6.57e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NMMECHGA_02966 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NMMECHGA_02967 1.22e-309 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NMMECHGA_02969 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
NMMECHGA_02970 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NMMECHGA_02971 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NMMECHGA_02972 8.47e-117 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NMMECHGA_02973 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NMMECHGA_02974 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
NMMECHGA_02975 7.6e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NMMECHGA_02976 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NMMECHGA_02977 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
NMMECHGA_02978 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMMECHGA_02979 1.23e-144 yrbG - - S - - - membrane
NMMECHGA_02980 1.46e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
NMMECHGA_02981 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
NMMECHGA_02982 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NMMECHGA_02983 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NMMECHGA_02984 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
NMMECHGA_02985 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NMMECHGA_02986 9.49e-136 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NMMECHGA_02987 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
NMMECHGA_02988 0.0 csbX - - EGP - - - the major facilitator superfamily
NMMECHGA_02989 1.13e-247 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
NMMECHGA_02990 2.32e-152 yrzF - - T - - - serine threonine protein kinase
NMMECHGA_02992 5.2e-67 - - - S - - - Family of unknown function (DUF5412)
NMMECHGA_02993 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
NMMECHGA_02994 1.67e-162 yebC - - K - - - transcriptional regulatory protein
NMMECHGA_02995 1.47e-69 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NMMECHGA_02996 2.43e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
NMMECHGA_02997 3.23e-272 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NMMECHGA_02998 2.15e-203 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
NMMECHGA_02999 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
NMMECHGA_03000 1.94e-289 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NMMECHGA_03001 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
NMMECHGA_03002 1.43e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
NMMECHGA_03003 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
NMMECHGA_03004 1.87e-306 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NMMECHGA_03005 4.97e-138 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
NMMECHGA_03006 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NMMECHGA_03007 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
NMMECHGA_03008 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NMMECHGA_03009 1.25e-206 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
NMMECHGA_03010 1.5e-186 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NMMECHGA_03011 8.33e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NMMECHGA_03012 1.75e-157 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NMMECHGA_03013 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
NMMECHGA_03014 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NMMECHGA_03015 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
NMMECHGA_03016 8.35e-163 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
NMMECHGA_03017 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
NMMECHGA_03018 6.77e-208 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
NMMECHGA_03019 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NMMECHGA_03020 2.22e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NMMECHGA_03021 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NMMECHGA_03022 1.53e-35 - - - - - - - -
NMMECHGA_03023 1.14e-250 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NMMECHGA_03024 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
NMMECHGA_03025 1.44e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NMMECHGA_03026 3.7e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
NMMECHGA_03027 3.03e-185 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NMMECHGA_03028 2.66e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NMMECHGA_03029 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
NMMECHGA_03030 1.37e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NMMECHGA_03031 4.77e-116 ysxD - - - - - - -
NMMECHGA_03032 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NMMECHGA_03033 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NMMECHGA_03034 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
NMMECHGA_03035 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NMMECHGA_03036 7.28e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NMMECHGA_03037 9.14e-239 ysoA - - H - - - Tetratricopeptide repeat
NMMECHGA_03038 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NMMECHGA_03039 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NMMECHGA_03040 3.02e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NMMECHGA_03041 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NMMECHGA_03042 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NMMECHGA_03043 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NMMECHGA_03044 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NMMECHGA_03046 4.03e-99 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
NMMECHGA_03047 7.62e-208 - - - N - - - domain, Protein
NMMECHGA_03048 4.09e-182 ysnF - - S - - - protein conserved in bacteria
NMMECHGA_03050 9.55e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NMMECHGA_03051 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NMMECHGA_03052 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NMMECHGA_03053 1.14e-255 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
NMMECHGA_03054 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NMMECHGA_03055 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
NMMECHGA_03056 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_03057 4.4e-101 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
NMMECHGA_03058 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NMMECHGA_03059 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NMMECHGA_03060 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
NMMECHGA_03061 2.45e-103 yslB - - S - - - Protein of unknown function (DUF2507)
NMMECHGA_03062 3.96e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NMMECHGA_03063 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NMMECHGA_03064 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NMMECHGA_03065 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
NMMECHGA_03067 1.37e-224 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
NMMECHGA_03068 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
NMMECHGA_03069 1.48e-174 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
NMMECHGA_03070 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_03071 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NMMECHGA_03072 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
NMMECHGA_03073 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NMMECHGA_03074 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
NMMECHGA_03075 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
NMMECHGA_03076 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NMMECHGA_03077 2.76e-218 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMMECHGA_03078 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NMMECHGA_03079 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NMMECHGA_03080 3.13e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMMECHGA_03081 4.37e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
NMMECHGA_03082 1.24e-260 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
NMMECHGA_03083 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
NMMECHGA_03084 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
NMMECHGA_03085 2.94e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
NMMECHGA_03086 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
NMMECHGA_03087 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
NMMECHGA_03088 6.34e-192 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
NMMECHGA_03089 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
NMMECHGA_03090 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
NMMECHGA_03091 2.24e-283 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NMMECHGA_03092 5.81e-185 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
NMMECHGA_03093 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NMMECHGA_03094 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
NMMECHGA_03095 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
NMMECHGA_03096 4.04e-241 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NMMECHGA_03097 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
NMMECHGA_03098 2.29e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
NMMECHGA_03099 1.49e-58 ysdA - - S - - - Membrane
NMMECHGA_03100 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NMMECHGA_03101 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NMMECHGA_03102 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NMMECHGA_03104 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NMMECHGA_03105 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NMMECHGA_03106 3.39e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
NMMECHGA_03107 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMMECHGA_03108 1.98e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
NMMECHGA_03109 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NMMECHGA_03111 3.46e-205 ytxC - - S - - - YtxC-like family
NMMECHGA_03112 2.3e-142 ytxB - - S - - - SNARE associated Golgi protein
NMMECHGA_03113 1.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NMMECHGA_03114 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
NMMECHGA_03115 6.95e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NMMECHGA_03116 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NMMECHGA_03117 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NMMECHGA_03118 9.85e-88 ytcD - - K - - - Transcriptional regulator
NMMECHGA_03119 9e-259 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
NMMECHGA_03120 4.54e-205 ytbE - - S - - - reductase
NMMECHGA_03121 1.9e-124 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NMMECHGA_03122 2.39e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
NMMECHGA_03123 4.73e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NMMECHGA_03124 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NMMECHGA_03125 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
NMMECHGA_03126 3.27e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMMECHGA_03127 1.48e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
NMMECHGA_03128 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
NMMECHGA_03129 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NMMECHGA_03130 9.38e-95 ytwI - - S - - - membrane
NMMECHGA_03131 5.51e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
NMMECHGA_03132 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
NMMECHGA_03133 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NMMECHGA_03134 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NMMECHGA_03135 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NMMECHGA_03136 8.83e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NMMECHGA_03137 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NMMECHGA_03138 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NMMECHGA_03139 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
NMMECHGA_03140 5.12e-112 ytrI - - - - - - -
NMMECHGA_03141 1.15e-39 - - - - - - - -
NMMECHGA_03142 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
NMMECHGA_03143 2.15e-63 ytpI - - S - - - YtpI-like protein
NMMECHGA_03144 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
NMMECHGA_03145 6.14e-204 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
NMMECHGA_03146 6.15e-299 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
NMMECHGA_03147 1.34e-163 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
NMMECHGA_03148 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMMECHGA_03149 5.26e-63 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
NMMECHGA_03150 3.42e-234 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMMECHGA_03151 5.43e-182 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NMMECHGA_03152 9.21e-153 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NMMECHGA_03153 9.59e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NMMECHGA_03154 2.19e-187 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NMMECHGA_03155 5.27e-194 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NMMECHGA_03156 3.42e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NMMECHGA_03157 6.8e-221 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
NMMECHGA_03158 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
NMMECHGA_03159 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMMECHGA_03161 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NMMECHGA_03162 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NMMECHGA_03163 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
NMMECHGA_03164 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NMMECHGA_03165 3.62e-222 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
NMMECHGA_03166 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NMMECHGA_03167 8.51e-96 ytfJ - - S - - - Sporulation protein YtfJ
NMMECHGA_03168 5.03e-150 ytfI - - S - - - Protein of unknown function (DUF2953)
NMMECHGA_03169 1.66e-111 yteJ - - S - - - RDD family
NMMECHGA_03170 5.87e-231 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
NMMECHGA_03171 4.15e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NMMECHGA_03172 0.0 ytcJ - - S - - - amidohydrolase
NMMECHGA_03173 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NMMECHGA_03174 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
NMMECHGA_03175 1.72e-286 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NMMECHGA_03176 1.36e-266 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NMMECHGA_03177 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NMMECHGA_03178 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NMMECHGA_03179 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NMMECHGA_03180 1.2e-141 yttP - - K - - - Transcriptional regulator
NMMECHGA_03181 7.94e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NMMECHGA_03182 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
NMMECHGA_03183 1.65e-140 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NMMECHGA_03185 2.16e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NMMECHGA_03186 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NMMECHGA_03187 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NMMECHGA_03188 5.07e-151 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
NMMECHGA_03189 1.81e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
NMMECHGA_03190 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NMMECHGA_03191 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NMMECHGA_03192 1.7e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NMMECHGA_03193 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NMMECHGA_03194 1.9e-72 ytxJ - - O - - - Protein of unknown function (DUF2847)
NMMECHGA_03195 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
NMMECHGA_03196 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NMMECHGA_03197 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NMMECHGA_03198 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NMMECHGA_03199 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NMMECHGA_03200 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
NMMECHGA_03201 2.61e-74 ytpP - - CO - - - Thioredoxin
NMMECHGA_03202 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
NMMECHGA_03203 9.11e-262 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
NMMECHGA_03204 6.75e-67 ytzB - - S - - - small secreted protein
NMMECHGA_03205 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NMMECHGA_03206 7.23e-192 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NMMECHGA_03207 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NMMECHGA_03208 9.51e-61 ytzH - - S - - - YtzH-like protein
NMMECHGA_03209 3.02e-192 ytmP - - M - - - Phosphotransferase
NMMECHGA_03210 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NMMECHGA_03211 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NMMECHGA_03212 4.04e-211 ytlQ - - - - - - -
NMMECHGA_03213 1.82e-131 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NMMECHGA_03214 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NMMECHGA_03215 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
NMMECHGA_03216 2.86e-287 pbuO - - S ko:K06901 - ko00000,ko02000 permease
NMMECHGA_03217 9.64e-253 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
NMMECHGA_03218 3.98e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NMMECHGA_03219 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
NMMECHGA_03220 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NMMECHGA_03221 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMMECHGA_03222 3.32e-292 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
NMMECHGA_03223 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
NMMECHGA_03224 2.14e-36 yteV - - S - - - Sporulation protein Cse60
NMMECHGA_03225 2.3e-151 yteU - - S - - - Integral membrane protein
NMMECHGA_03226 1.07e-315 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
NMMECHGA_03227 2.76e-93 yteS - - G - - - transport
NMMECHGA_03228 2.19e-274 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NMMECHGA_03229 1.08e-219 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
NMMECHGA_03230 0.0 ytdP - - K - - - Transcriptional regulator
NMMECHGA_03231 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
NMMECHGA_03232 2.93e-184 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
NMMECHGA_03233 1.28e-177 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
NMMECHGA_03234 2.6e-278 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NMMECHGA_03235 1.78e-241 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NMMECHGA_03236 8.98e-158 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NMMECHGA_03237 4.28e-274 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NMMECHGA_03238 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NMMECHGA_03239 2.24e-179 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NMMECHGA_03240 1.67e-221 - - - S - - - Acetyl xylan esterase (AXE1)
NMMECHGA_03241 8.46e-240 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_03242 1.6e-306 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NMMECHGA_03243 2.35e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NMMECHGA_03244 2.19e-185 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NMMECHGA_03245 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
NMMECHGA_03246 1.22e-68 ytwF - - P - - - Sulfurtransferase
NMMECHGA_03247 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NMMECHGA_03248 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
NMMECHGA_03249 6.61e-184 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NMMECHGA_03250 2.45e-268 yttB - - EGP - - - Major facilitator superfamily
NMMECHGA_03251 1.16e-77 yttA - - S - - - Pfam Transposase IS66
NMMECHGA_03252 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
NMMECHGA_03253 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_03254 1.3e-238 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
NMMECHGA_03255 2.71e-168 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMMECHGA_03256 2.31e-295 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NMMECHGA_03257 2.91e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_03258 5.12e-181 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
NMMECHGA_03259 6.07e-196 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NMMECHGA_03260 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_03261 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
NMMECHGA_03263 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
NMMECHGA_03264 9.56e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
NMMECHGA_03265 2.26e-135 ytqB - - J - - - Putative rRNA methylase
NMMECHGA_03266 2.78e-275 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
NMMECHGA_03267 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
NMMECHGA_03268 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NMMECHGA_03269 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NMMECHGA_03270 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NMMECHGA_03271 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NMMECHGA_03272 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NMMECHGA_03273 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
NMMECHGA_03274 6.67e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NMMECHGA_03275 7.95e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NMMECHGA_03276 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NMMECHGA_03277 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NMMECHGA_03278 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NMMECHGA_03279 6.47e-81 ytkC - - S - - - Bacteriophage holin family
NMMECHGA_03280 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NMMECHGA_03282 6.79e-95 ytkA - - S - - - YtkA-like
NMMECHGA_03283 1.39e-111 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NMMECHGA_03284 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NMMECHGA_03285 1.44e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NMMECHGA_03286 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NMMECHGA_03287 6.96e-240 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NMMECHGA_03288 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
NMMECHGA_03289 9.24e-192 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NMMECHGA_03290 7.13e-294 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NMMECHGA_03291 1.68e-176 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NMMECHGA_03292 4.4e-216 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NMMECHGA_03293 8.26e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NMMECHGA_03294 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NMMECHGA_03295 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NMMECHGA_03296 9.85e-197 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NMMECHGA_03297 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NMMECHGA_03298 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NMMECHGA_03299 1.75e-168 yteA - - T - - - COG1734 DnaK suppressor protein
NMMECHGA_03300 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
NMMECHGA_03301 2.03e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NMMECHGA_03302 2.48e-227 ytcB - - M - - - NAD-dependent epimerase dehydratase
NMMECHGA_03303 3.4e-296 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
NMMECHGA_03305 4.88e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
NMMECHGA_03306 8.31e-275 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
NMMECHGA_03307 3.68e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
NMMECHGA_03308 5.66e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
NMMECHGA_03309 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NMMECHGA_03310 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
NMMECHGA_03311 1.07e-237 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
NMMECHGA_03312 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NMMECHGA_03313 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NMMECHGA_03335 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NMMECHGA_03336 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
NMMECHGA_03337 5.71e-121 - - - M - - - FR47-like protein
NMMECHGA_03338 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
NMMECHGA_03339 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
NMMECHGA_03340 1.95e-109 yuaE - - S - - - DinB superfamily
NMMECHGA_03341 1.42e-137 yuaD - - - - - - -
NMMECHGA_03342 2.46e-291 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
NMMECHGA_03343 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NMMECHGA_03344 2.39e-121 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
NMMECHGA_03345 5.83e-118 yuaB - - - - - - -
NMMECHGA_03346 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NMMECHGA_03347 3.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
NMMECHGA_03348 3.31e-52 yubF - - S - - - yiaA/B two helix domain
NMMECHGA_03349 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NMMECHGA_03350 0.0 yubD - - P - - - Major Facilitator Superfamily
NMMECHGA_03351 2.29e-112 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
NMMECHGA_03352 8.33e-60 - - - S - - - YolD-like protein
NMMECHGA_03354 2.35e-38 - - - K - - - Helix-turn-helix domain
NMMECHGA_03357 1.61e-38 - - - KLT - - - serine threonine protein kinase
NMMECHGA_03358 8.02e-138 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NMMECHGA_03359 1.58e-41 xhlB - - S - - - SPP1 phage holin
NMMECHGA_03360 1.95e-37 xhlA - - S - - - Haemolysin XhlA
NMMECHGA_03365 2.5e-217 - - - L - - - Phage minor structural protein
NMMECHGA_03366 1.75e-40 - - - S - - - Phage tail protein
NMMECHGA_03367 1.99e-144 - - - D - - - minor tail protein
NMMECHGA_03368 1.61e-46 - - - S - - - Bacteriophage Gp15 protein
NMMECHGA_03370 3.38e-53 - - - N - - - Belongs to the glycosyl hydrolase family 6
NMMECHGA_03372 2.49e-28 - - - S - - - Minor capsid protein
NMMECHGA_03374 2.32e-27 - - - - - - - -
NMMECHGA_03375 5.32e-10 chiA - - G - - - Belongs to the glycosyl hydrolase 18 family
NMMECHGA_03376 1.16e-123 - - - - - - - -
NMMECHGA_03377 3.56e-25 - - - - - - - -
NMMECHGA_03378 4.03e-116 - - - M - - - Phage minor capsid protein 2
NMMECHGA_03379 1.65e-210 - - - S - - - portal protein
NMMECHGA_03380 3.71e-256 - - - S ko:K06909 - ko00000 Terminase RNAseH like domain
NMMECHGA_03381 3.39e-106 yqaS - - L - - - DNA packaging
NMMECHGA_03383 5.28e-105 - - - L - - - Transposase
NMMECHGA_03390 2.49e-59 - - - S - - - dUTPase
NMMECHGA_03393 1.14e-131 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NMMECHGA_03396 6.2e-35 yqaO - - S - - - Phage-like element PBSX protein XtrA
NMMECHGA_03398 3.16e-71 - - - S - - - Protein of unknown function (DUF1064)
NMMECHGA_03400 1.13e-15 - - - S - - - YopX protein
NMMECHGA_03402 6.06e-102 yqaM - - L - - - IstB-like ATP binding protein
NMMECHGA_03403 8.15e-97 yqaL - - L - - - DnaD domain protein
NMMECHGA_03405 2.55e-87 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
NMMECHGA_03406 9.73e-124 - - - - - - - -
NMMECHGA_03411 3.35e-105 - - - - - - - -
NMMECHGA_03412 8.89e-57 - - - S - - - DNA binding
NMMECHGA_03413 8.03e-22 - - - S - - - Helix-turn-helix domain
NMMECHGA_03414 3e-05 - - - K - - - Helix-turn-helix domain
NMMECHGA_03415 3.26e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
NMMECHGA_03418 1.38e-63 xkdA - - E - - - IrrE N-terminal-like domain
NMMECHGA_03419 1.44e-210 int7 - - L - - - Belongs to the 'phage' integrase family
NMMECHGA_03424 1.92e-14 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_03427 2.3e-13 - - - - - - - -
NMMECHGA_03429 2.84e-56 - - - - - - - -
NMMECHGA_03430 1.89e-52 - - - I - - - Pfam Lipase (class 3)
NMMECHGA_03431 2.8e-229 - - - I - - - Pfam Lipase (class 3)
NMMECHGA_03432 2.11e-66 - - - S - - - Protein of unknown function (DUF1433)
NMMECHGA_03433 9.64e-49 - - - S - - - Protein of unknown function (DUF1433)
NMMECHGA_03434 6.85e-36 - - - S - - - Domain of unknown function (DUF4917)
NMMECHGA_03435 1.54e-05 - - - - - - - -
NMMECHGA_03436 0.0 - - - S - - - Pfam Transposase IS66
NMMECHGA_03437 0.0 - - - S - - - peptidoglycan catabolic process
NMMECHGA_03441 3.53e-119 - - - S - - - Phage capsid family
NMMECHGA_03442 1.85e-38 - - - S - - - Domain of unknown function (DUF4355)
NMMECHGA_03443 1.37e-154 - - - S - - - Phage portal protein, SPP1 Gp6-like
NMMECHGA_03444 7.53e-179 - - - S - - - TIGRFAM Phage
NMMECHGA_03445 4.7e-97 - - - L - - - Resolvase, N terminal domain
NMMECHGA_03446 1.89e-13 - - - S - - - Helix-turn-helix of insertion element transposase
NMMECHGA_03448 1.07e-37 - - - - - - - -
NMMECHGA_03449 1.59e-87 - - - - - - - -
NMMECHGA_03450 4.1e-55 - - - - - - - -
NMMECHGA_03454 4.39e-280 - - - - - - - -
NMMECHGA_03461 2.29e-67 - - - - - - - -
NMMECHGA_03464 1.3e-72 - - - L - - - Arm DNA-binding domain
NMMECHGA_03466 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NMMECHGA_03467 7.02e-252 yubA - - S - - - transporter activity
NMMECHGA_03468 1.29e-235 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NMMECHGA_03469 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
NMMECHGA_03470 2.02e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
NMMECHGA_03471 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NMMECHGA_03472 2.87e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NMMECHGA_03473 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
NMMECHGA_03474 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NMMECHGA_03475 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NMMECHGA_03476 3.44e-297 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NMMECHGA_03477 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NMMECHGA_03478 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
NMMECHGA_03479 1.44e-47 - - - - - - - -
NMMECHGA_03480 1.22e-93 yugU - - S - - - Uncharacterised protein family UPF0047
NMMECHGA_03481 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NMMECHGA_03482 2.52e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NMMECHGA_03483 2.77e-149 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
NMMECHGA_03484 1.58e-50 - - - - - - - -
NMMECHGA_03485 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
NMMECHGA_03486 2.92e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
NMMECHGA_03487 3.48e-94 yugN - - S - - - YugN-like family
NMMECHGA_03489 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NMMECHGA_03490 3.76e-289 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
NMMECHGA_03491 8.16e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
NMMECHGA_03492 1.28e-45 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
NMMECHGA_03493 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NMMECHGA_03494 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
NMMECHGA_03495 6.74e-112 alaR - - K - - - Transcriptional regulator
NMMECHGA_03496 8.13e-200 yugF - - I - - - Hydrolase
NMMECHGA_03497 1.58e-54 yugE - - S - - - Domain of unknown function (DUF1871)
NMMECHGA_03498 1.16e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NMMECHGA_03499 1.18e-293 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMMECHGA_03500 8.69e-92 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
NMMECHGA_03501 2.44e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
NMMECHGA_03503 8.9e-242 yuxJ - - EGP - - - Major facilitator superfamily
NMMECHGA_03504 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
NMMECHGA_03505 1.11e-96 yuxK - - S - - - protein conserved in bacteria
NMMECHGA_03506 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
NMMECHGA_03507 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NMMECHGA_03508 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NMMECHGA_03509 3.66e-253 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
NMMECHGA_03510 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_03511 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NMMECHGA_03512 4.9e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NMMECHGA_03513 7.99e-309 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
NMMECHGA_03514 2.46e-22 - - - - - - - -
NMMECHGA_03515 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NMMECHGA_03516 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMMECHGA_03517 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMMECHGA_03518 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMMECHGA_03519 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMMECHGA_03520 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMMECHGA_03521 1.65e-76 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
NMMECHGA_03522 2.72e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
NMMECHGA_03523 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMMECHGA_03524 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMMECHGA_03526 1.62e-190 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
NMMECHGA_03527 6.29e-10 - - - S - - - DegQ (SacQ) family
NMMECHGA_03528 8.73e-09 yuzC - - - - - - -
NMMECHGA_03529 9.77e-297 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
NMMECHGA_03530 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NMMECHGA_03531 3.82e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
NMMECHGA_03532 2.11e-85 - - - S - - - Protein of unknown function (DUF1694)
NMMECHGA_03533 1.63e-52 yueH - - S - - - YueH-like protein
NMMECHGA_03534 1.19e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
NMMECHGA_03535 2.73e-244 yueF - - S - - - transporter activity
NMMECHGA_03536 1.65e-06 - - - S - - - Protein of unknown function (DUF2283)
NMMECHGA_03537 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
NMMECHGA_03538 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
NMMECHGA_03539 5.85e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMMECHGA_03540 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
NMMECHGA_03541 0.0 yueB - - S - - - type VII secretion protein EsaA
NMMECHGA_03542 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NMMECHGA_03543 2.47e-270 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
NMMECHGA_03544 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
NMMECHGA_03545 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
NMMECHGA_03546 5.98e-292 yukF - - QT - - - Transcriptional regulator
NMMECHGA_03547 4.69e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
NMMECHGA_03548 2.07e-169 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
NMMECHGA_03549 1.42e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
NMMECHGA_03550 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMMECHGA_03551 3.15e-228 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
NMMECHGA_03552 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
NMMECHGA_03553 2.86e-288 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NMMECHGA_03554 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NMMECHGA_03555 7.35e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
NMMECHGA_03556 1.37e-156 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
NMMECHGA_03557 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
NMMECHGA_03558 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
NMMECHGA_03559 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NMMECHGA_03560 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
NMMECHGA_03561 3.14e-149 yuiC - - S - - - protein conserved in bacteria
NMMECHGA_03562 9.78e-47 yuiB - - S - - - Putative membrane protein
NMMECHGA_03563 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NMMECHGA_03564 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
NMMECHGA_03566 7.47e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NMMECHGA_03567 3.19e-146 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
NMMECHGA_03568 1.39e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMMECHGA_03569 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
NMMECHGA_03570 3.2e-207 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NMMECHGA_03571 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NMMECHGA_03572 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
NMMECHGA_03573 9.17e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NMMECHGA_03574 2.22e-73 yuzD - - S - - - protein conserved in bacteria
NMMECHGA_03575 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
NMMECHGA_03576 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
NMMECHGA_03577 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NMMECHGA_03578 9.76e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NMMECHGA_03579 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NMMECHGA_03580 4.45e-253 yutH - - S - - - Spore coat protein
NMMECHGA_03581 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
NMMECHGA_03582 2.13e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NMMECHGA_03583 1.96e-98 yutE - - S - - - Protein of unknown function DUF86
NMMECHGA_03584 3.2e-63 yutD - - S - - - protein conserved in bacteria
NMMECHGA_03585 1.34e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NMMECHGA_03586 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NMMECHGA_03587 7.63e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
NMMECHGA_03588 2.46e-171 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
NMMECHGA_03589 5.67e-64 yunC - - S - - - Domain of unknown function (DUF1805)
NMMECHGA_03590 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NMMECHGA_03591 1.53e-179 yunE - - S ko:K07090 - ko00000 membrane transporter protein
NMMECHGA_03592 1e-218 yunF - - S - - - Protein of unknown function DUF72
NMMECHGA_03593 1.07e-79 yunG - - - - - - -
NMMECHGA_03594 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NMMECHGA_03595 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
NMMECHGA_03596 9e-295 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
NMMECHGA_03597 5.5e-284 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
NMMECHGA_03598 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NMMECHGA_03599 4.38e-74 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NMMECHGA_03601 0.000154 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NMMECHGA_03602 5.71e-121 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NMMECHGA_03603 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NMMECHGA_03604 7.39e-189 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NMMECHGA_03605 7.22e-142 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
NMMECHGA_03606 1.76e-234 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NMMECHGA_03607 9.93e-305 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NMMECHGA_03608 8.34e-295 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NMMECHGA_03609 6.27e-216 bsn - - L - - - Ribonuclease
NMMECHGA_03610 2.42e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NMMECHGA_03611 1.02e-173 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
NMMECHGA_03612 1.3e-206 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
NMMECHGA_03613 1.94e-216 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
NMMECHGA_03614 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NMMECHGA_03615 6.75e-306 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
NMMECHGA_03616 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NMMECHGA_03617 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
NMMECHGA_03618 3.2e-265 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
NMMECHGA_03620 9.61e-56 - - - - - - - -
NMMECHGA_03621 7.61e-193 - - - - - - - -
NMMECHGA_03622 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
NMMECHGA_03623 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
NMMECHGA_03624 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NMMECHGA_03625 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
NMMECHGA_03626 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NMMECHGA_03627 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NMMECHGA_03628 8.33e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
NMMECHGA_03629 6.1e-131 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
NMMECHGA_03630 1.76e-235 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NMMECHGA_03631 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
NMMECHGA_03632 8.14e-73 yusE - - CO - - - Thioredoxin
NMMECHGA_03633 1.08e-96 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
NMMECHGA_03634 1.48e-53 yusG - - S - - - Protein of unknown function (DUF2553)
NMMECHGA_03635 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NMMECHGA_03636 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
NMMECHGA_03637 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NMMECHGA_03638 1.56e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
NMMECHGA_03639 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
NMMECHGA_03640 1.11e-13 - - - S - - - YuzL-like protein
NMMECHGA_03641 1.41e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NMMECHGA_03642 1.29e-53 - - - - - - - -
NMMECHGA_03643 8.66e-70 yusN - - M - - - Coat F domain
NMMECHGA_03644 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
NMMECHGA_03645 0.0 yusP - - P - - - Major facilitator superfamily
NMMECHGA_03646 9.82e-84 yusQ - - S - - - Tautomerase enzyme
NMMECHGA_03647 9.13e-134 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NMMECHGA_03648 1.2e-203 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
NMMECHGA_03649 1.23e-62 yusU - - S - - - Protein of unknown function (DUF2573)
NMMECHGA_03650 8.74e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NMMECHGA_03651 1.72e-88 - - - S - - - YusW-like protein
NMMECHGA_03652 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
NMMECHGA_03653 6.38e-196 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NMMECHGA_03654 1.07e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
NMMECHGA_03655 1.07e-302 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMMECHGA_03656 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMMECHGA_03657 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMMECHGA_03658 3.06e-204 yuxN - - K - - - Transcriptional regulator
NMMECHGA_03659 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NMMECHGA_03660 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
NMMECHGA_03661 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NMMECHGA_03662 3.94e-251 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NMMECHGA_03663 4.33e-243 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
NMMECHGA_03664 4.46e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMMECHGA_03665 2.74e-244 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMMECHGA_03666 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
NMMECHGA_03667 8.92e-176 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
NMMECHGA_03668 4.05e-142 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NMMECHGA_03669 1.77e-81 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
NMMECHGA_03670 1.13e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NMMECHGA_03671 5.32e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
NMMECHGA_03672 4.66e-312 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NMMECHGA_03673 3.29e-237 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMMECHGA_03674 8.18e-216 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NMMECHGA_03675 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NMMECHGA_03676 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
NMMECHGA_03677 0.0 yvrG - - T - - - Histidine kinase
NMMECHGA_03678 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMMECHGA_03679 6.16e-33 - - - - - - - -
NMMECHGA_03680 5.77e-127 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
NMMECHGA_03681 3.46e-26 - - - S - - - YvrJ protein family
NMMECHGA_03682 1.53e-290 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NMMECHGA_03683 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
NMMECHGA_03684 3.36e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NMMECHGA_03685 3.82e-158 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_03686 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
NMMECHGA_03687 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NMMECHGA_03688 9.64e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMMECHGA_03689 3.47e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMMECHGA_03690 4.45e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NMMECHGA_03691 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
NMMECHGA_03692 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
NMMECHGA_03693 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
NMMECHGA_03694 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
NMMECHGA_03695 8.87e-215 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
NMMECHGA_03696 5.78e-173 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
NMMECHGA_03697 1.43e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
NMMECHGA_03698 2.52e-200 yvgN - - S - - - reductase
NMMECHGA_03699 9.32e-112 yvgO - - - - - - -
NMMECHGA_03700 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
NMMECHGA_03701 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NMMECHGA_03702 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NMMECHGA_03703 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NMMECHGA_03704 3.88e-140 yvgT - - S - - - membrane
NMMECHGA_03705 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
NMMECHGA_03706 3.45e-137 bdbD - - O - - - Thioredoxin
NMMECHGA_03707 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NMMECHGA_03708 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NMMECHGA_03709 3.66e-41 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
NMMECHGA_03710 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
NMMECHGA_03711 3.3e-246 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NMMECHGA_03712 5.09e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NMMECHGA_03713 0.0 - - - S - - - Fusaric acid resistance protein-like
NMMECHGA_03714 9.61e-96 yvaD - - S - - - Family of unknown function (DUF5360)
NMMECHGA_03715 3.52e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
NMMECHGA_03716 3.9e-125 - - - K - - - Bacterial regulatory proteins, tetR family
NMMECHGA_03717 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NMMECHGA_03719 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NMMECHGA_03720 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NMMECHGA_03721 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
NMMECHGA_03722 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
NMMECHGA_03723 4.04e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
NMMECHGA_03724 3.44e-48 yvzC - - K - - - transcriptional
NMMECHGA_03725 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
NMMECHGA_03726 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NMMECHGA_03727 3.85e-72 yvaP - - K - - - transcriptional
NMMECHGA_03728 7.34e-317 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NMMECHGA_03729 2.26e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NMMECHGA_03730 2.27e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NMMECHGA_03731 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NMMECHGA_03732 9.58e-267 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NMMECHGA_03733 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NMMECHGA_03734 4.8e-137 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NMMECHGA_03735 1.49e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NMMECHGA_03736 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NMMECHGA_03737 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NMMECHGA_03738 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NMMECHGA_03739 3.94e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
NMMECHGA_03740 1.03e-145 yvbH - - S - - - YvbH-like oligomerisation region
NMMECHGA_03741 2.78e-157 yvbI - - M - - - Membrane
NMMECHGA_03742 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NMMECHGA_03743 6.83e-97 yvbK - - K - - - acetyltransferase
NMMECHGA_03744 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NMMECHGA_03745 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
NMMECHGA_03746 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NMMECHGA_03747 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NMMECHGA_03748 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NMMECHGA_03749 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NMMECHGA_03750 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NMMECHGA_03751 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
NMMECHGA_03752 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMMECHGA_03753 3.45e-206 yvbU - - K - - - Transcriptional regulator
NMMECHGA_03754 5.59e-198 yvbV - - EG - - - EamA-like transporter family
NMMECHGA_03755 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NMMECHGA_03756 1.48e-247 - - - S - - - Glycosyl hydrolase
NMMECHGA_03757 1.39e-170 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NMMECHGA_03758 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NMMECHGA_03759 1.06e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NMMECHGA_03760 4.36e-136 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMMECHGA_03761 3.11e-251 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMMECHGA_03762 5.01e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NMMECHGA_03763 3.16e-204 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
NMMECHGA_03764 2.95e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
NMMECHGA_03765 3.12e-258 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
NMMECHGA_03766 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
NMMECHGA_03767 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
NMMECHGA_03768 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
NMMECHGA_03769 8.76e-300 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
NMMECHGA_03770 1.32e-291 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
NMMECHGA_03771 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_03772 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
NMMECHGA_03773 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NMMECHGA_03774 8.58e-307 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NMMECHGA_03775 5.69e-44 yvfG - - S - - - YvfG protein
NMMECHGA_03776 1.85e-241 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
NMMECHGA_03777 3.54e-277 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
NMMECHGA_03778 5.46e-75 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NMMECHGA_03779 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NMMECHGA_03780 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMMECHGA_03781 1.53e-242 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NMMECHGA_03782 1.15e-260 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
NMMECHGA_03783 2.75e-245 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NMMECHGA_03784 3.59e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
NMMECHGA_03785 1.45e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NMMECHGA_03786 3.58e-201 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
NMMECHGA_03787 2.23e-281 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
NMMECHGA_03788 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NMMECHGA_03789 4.59e-149 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NMMECHGA_03790 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
NMMECHGA_03791 4.17e-97 - - - K ko:K19417 - ko00000,ko03000 transcriptional
NMMECHGA_03792 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
NMMECHGA_03793 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
NMMECHGA_03794 5.45e-97 - - - S - - - Protein of unknown function (DUF3237)
NMMECHGA_03795 2.06e-161 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NMMECHGA_03796 0.0 pbpE - - V - - - Beta-lactamase
NMMECHGA_03797 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
NMMECHGA_03798 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NMMECHGA_03799 0.0 ybeC - - E - - - amino acid
NMMECHGA_03800 6.76e-137 yvdT_1 - - K - - - Transcriptional regulator
NMMECHGA_03801 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NMMECHGA_03802 2.08e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
NMMECHGA_03803 1.12e-121 yvdQ - - S - - - Protein of unknown function (DUF3231)
NMMECHGA_03804 5.17e-222 - - - S - - - Patatin-like phospholipase
NMMECHGA_03806 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NMMECHGA_03807 1.74e-152 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NMMECHGA_03808 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NMMECHGA_03809 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
NMMECHGA_03810 2.79e-197 malA - - S - - - Protein of unknown function (DUF1189)
NMMECHGA_03811 5.62e-189 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
NMMECHGA_03812 8.65e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
NMMECHGA_03813 9.87e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
NMMECHGA_03814 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
NMMECHGA_03815 1.54e-221 yvdE - - K - - - Transcriptional regulator
NMMECHGA_03816 5.37e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NMMECHGA_03817 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
NMMECHGA_03818 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NMMECHGA_03819 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NMMECHGA_03820 1.9e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMMECHGA_03821 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
NMMECHGA_03822 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_03823 1.38e-251 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
NMMECHGA_03824 9.05e-170 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMMECHGA_03825 1.61e-44 - - - - - - - -
NMMECHGA_03826 5.64e-183 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
NMMECHGA_03827 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
NMMECHGA_03828 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NMMECHGA_03829 3.88e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NMMECHGA_03830 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NMMECHGA_03831 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NMMECHGA_03832 1.18e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NMMECHGA_03833 2.2e-179 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
NMMECHGA_03834 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
NMMECHGA_03835 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NMMECHGA_03837 8.03e-76 - - - - - - - -
NMMECHGA_03838 2.34e-303 - - - - - - - -
NMMECHGA_03839 6.75e-114 - - - - - - - -
NMMECHGA_03840 9.81e-142 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
NMMECHGA_03841 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NMMECHGA_03842 1.54e-165 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NMMECHGA_03843 1.15e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NMMECHGA_03844 4.96e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NMMECHGA_03845 1.49e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NMMECHGA_03846 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NMMECHGA_03847 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NMMECHGA_03848 2.14e-179 yvpB - - NU - - - protein conserved in bacteria
NMMECHGA_03849 1.05e-151 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
NMMECHGA_03850 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NMMECHGA_03851 6.15e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NMMECHGA_03852 2.06e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
NMMECHGA_03853 2.61e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NMMECHGA_03854 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NMMECHGA_03855 5.92e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NMMECHGA_03856 1.43e-164 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NMMECHGA_03857 3.02e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
NMMECHGA_03858 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
NMMECHGA_03859 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
NMMECHGA_03860 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NMMECHGA_03861 5.54e-219 yvlB - - S - - - Putative adhesin
NMMECHGA_03862 8.09e-65 yvlA - - - - - - -
NMMECHGA_03863 4.54e-45 yvkN - - - - - - -
NMMECHGA_03864 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NMMECHGA_03865 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NMMECHGA_03866 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NMMECHGA_03867 2.54e-42 csbA - - S - - - protein conserved in bacteria
NMMECHGA_03868 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
NMMECHGA_03869 4.77e-130 yvkB - - K - - - Transcriptional regulator
NMMECHGA_03870 5.24e-296 yvkA - - P - - - -transporter
NMMECHGA_03871 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMMECHGA_03872 1.38e-73 swrA - - S - - - Swarming motility protein
NMMECHGA_03873 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NMMECHGA_03874 7.74e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NMMECHGA_03875 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
NMMECHGA_03876 4.42e-73 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NMMECHGA_03877 1.08e-183 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NMMECHGA_03878 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NMMECHGA_03879 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NMMECHGA_03880 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NMMECHGA_03881 2.46e-67 - - - - - - - -
NMMECHGA_03882 3.1e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
NMMECHGA_03883 1.48e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
NMMECHGA_03884 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NMMECHGA_03885 3.03e-74 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
NMMECHGA_03886 1.01e-106 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NMMECHGA_03887 2.58e-41 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NMMECHGA_03888 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NMMECHGA_03889 2.42e-92 yviE - - - - - - -
NMMECHGA_03890 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
NMMECHGA_03891 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
NMMECHGA_03892 7.06e-102 yvyG - - NOU - - - FlgN protein
NMMECHGA_03893 5.05e-52 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
NMMECHGA_03894 1.83e-96 yvyF - - S - - - flagellar protein
NMMECHGA_03895 3.79e-103 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
NMMECHGA_03896 1.04e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
NMMECHGA_03897 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NMMECHGA_03898 7.19e-198 degV - - S - - - protein conserved in bacteria
NMMECHGA_03899 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMMECHGA_03900 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NMMECHGA_03901 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
NMMECHGA_03902 2.38e-223 yvhJ - - K - - - Transcriptional regulator
NMMECHGA_03903 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NMMECHGA_03904 3.96e-295 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
NMMECHGA_03905 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NMMECHGA_03906 1.42e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
NMMECHGA_03907 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
NMMECHGA_03908 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NMMECHGA_03909 4.86e-280 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
NMMECHGA_03910 1.46e-315 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMMECHGA_03911 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NMMECHGA_03912 9e-109 - - - M - - - Glycosyltransferase like family 2
NMMECHGA_03913 1.06e-263 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NMMECHGA_03914 0.0 lytB - - D - - - Stage II sporulation protein
NMMECHGA_03915 9.07e-16 - - - - - - - -
NMMECHGA_03916 1.16e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NMMECHGA_03917 8.63e-274 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NMMECHGA_03918 2.94e-103 - - - M - - - Glycosyltransferase like family 2
NMMECHGA_03919 1.72e-118 - - - M - - - Glycosyl transferases group 1
NMMECHGA_03921 2.74e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NMMECHGA_03922 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NMMECHGA_03923 1.37e-167 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
NMMECHGA_03924 1.43e-102 - - - - - - - -
NMMECHGA_03925 5.37e-68 - - - - - - - -
NMMECHGA_03926 1.52e-248 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NMMECHGA_03927 1.47e-106 - - - M - - - Glycosyltransferase like family 2
NMMECHGA_03928 9.24e-180 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NMMECHGA_03929 2.29e-74 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
NMMECHGA_03930 6.82e-111 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NMMECHGA_03931 4.41e-116 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NMMECHGA_03932 1.46e-134 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NMMECHGA_03933 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NMMECHGA_03934 4.73e-110 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NMMECHGA_03935 1.42e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NMMECHGA_03936 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NMMECHGA_03937 2.73e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NMMECHGA_03938 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NMMECHGA_03939 7.34e-249 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NMMECHGA_03940 1.85e-265 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
NMMECHGA_03941 3.71e-314 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NMMECHGA_03942 8.57e-222 ywtF_2 - - K - - - Transcriptional regulator
NMMECHGA_03943 7.24e-205 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NMMECHGA_03944 4.73e-306 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NMMECHGA_03945 2.29e-29 ywtC - - - - - - -
NMMECHGA_03946 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NMMECHGA_03947 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
NMMECHGA_03948 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
NMMECHGA_03949 9.35e-228 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
NMMECHGA_03950 7.52e-206 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NMMECHGA_03951 2.28e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NMMECHGA_03952 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NMMECHGA_03953 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NMMECHGA_03954 1.56e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
NMMECHGA_03955 9.76e-120 batE - - T - - - Sh3 type 3 domain protein
NMMECHGA_03956 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
NMMECHGA_03957 1.45e-124 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
NMMECHGA_03958 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NMMECHGA_03959 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NMMECHGA_03960 3.36e-218 alsR - - K - - - LysR substrate binding domain
NMMECHGA_03961 9.31e-279 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NMMECHGA_03962 4.33e-162 ywrJ - - - - - - -
NMMECHGA_03963 7.86e-162 cotB - - - ko:K06325 - ko00000 -
NMMECHGA_03964 2.08e-265 cotH - - M ko:K06330 - ko00000 Spore Coat
NMMECHGA_03965 1.03e-17 - - - - - - - -
NMMECHGA_03966 4.35e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NMMECHGA_03967 7.97e-71 - - - S - - - Domain of unknown function (DUF4181)
NMMECHGA_03968 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NMMECHGA_03969 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NMMECHGA_03970 2.25e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
NMMECHGA_03971 4.27e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
NMMECHGA_03973 2.49e-128 ywqN - - S - - - NAD(P)H-dependent
NMMECHGA_03974 4.73e-209 - - - K - - - Transcriptional regulator
NMMECHGA_03975 7.5e-151 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NMMECHGA_03977 9.77e-48 - - - S ko:K11904,ko:K21493 ko03070,map03070 ko00000,ko00001,ko00002,ko01000,ko02044,ko02048 protein secretion by the type VII secretion system
NMMECHGA_03978 5.5e-94 ywqJ - - S - - - Pre-toxin TG
NMMECHGA_03979 1.3e-23 - - - - - - - -
NMMECHGA_03980 1.77e-26 - - - - - - - -
NMMECHGA_03981 3.64e-264 - - - L - - - nucleic acid phosphodiester bond hydrolysis
NMMECHGA_03982 1.04e-51 ywqI - - S - - - Family of unknown function (DUF5344)
NMMECHGA_03984 2.28e-192 ywqG - - S - - - Domain of unknown function (DUF1963)
NMMECHGA_03985 4.66e-313 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NMMECHGA_03986 2.05e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
NMMECHGA_03987 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NMMECHGA_03988 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
NMMECHGA_03989 3.6e-25 - - - - - - - -
NMMECHGA_03990 0.0 ywqB - - S - - - SWIM zinc finger
NMMECHGA_03991 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NMMECHGA_03992 3.72e-202 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NMMECHGA_03993 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NMMECHGA_03994 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
NMMECHGA_03995 3.04e-87 ywpG - - - - - - -
NMMECHGA_03996 8.81e-89 ywpF - - S - - - YwpF-like protein
NMMECHGA_03997 3.81e-67 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NMMECHGA_03998 2.93e-189 ywpD - - T - - - Histidine kinase
NMMECHGA_03999 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NMMECHGA_04000 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NMMECHGA_04001 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
NMMECHGA_04002 5.58e-180 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NMMECHGA_04003 1.19e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NMMECHGA_04004 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
NMMECHGA_04005 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
NMMECHGA_04006 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
NMMECHGA_04007 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NMMECHGA_04009 1.14e-309 ywoF - - P - - - Right handed beta helix region
NMMECHGA_04010 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
NMMECHGA_04011 1.27e-305 ywoD - - EGP - - - Major facilitator superfamily
NMMECHGA_04012 1.04e-133 yjgF - - Q - - - Isochorismatase family
NMMECHGA_04013 3.04e-102 - - - - - - - -
NMMECHGA_04014 1.12e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
NMMECHGA_04015 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
NMMECHGA_04016 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
NMMECHGA_04017 2.7e-94 ywnJ - - S - - - VanZ like family
NMMECHGA_04018 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NMMECHGA_04019 5.19e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
NMMECHGA_04020 1.85e-21 ywnC - - S - - - Family of unknown function (DUF5362)
NMMECHGA_04021 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
NMMECHGA_04022 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMMECHGA_04023 2.69e-181 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
NMMECHGA_04024 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
NMMECHGA_04025 2.5e-146 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
NMMECHGA_04026 4.58e-85 ywnA - - K - - - Transcriptional regulator
NMMECHGA_04027 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NMMECHGA_04028 3.2e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
NMMECHGA_04029 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
NMMECHGA_04031 1.11e-21 csbD - - K - - - CsbD-like
NMMECHGA_04032 1.12e-109 ywmF - - S - - - Peptidase M50
NMMECHGA_04033 2.51e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NMMECHGA_04034 1.08e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NMMECHGA_04035 9.06e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NMMECHGA_04037 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NMMECHGA_04038 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NMMECHGA_04039 1.69e-234 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
NMMECHGA_04040 1.17e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMMECHGA_04041 3.65e-169 ywmB - - S - - - TATA-box binding
NMMECHGA_04042 3.74e-44 ywzB - - S - - - membrane
NMMECHGA_04043 1.44e-113 ywmA - - - - - - -
NMMECHGA_04044 3.89e-72 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NMMECHGA_04045 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NMMECHGA_04046 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NMMECHGA_04047 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NMMECHGA_04048 7.94e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMMECHGA_04049 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NMMECHGA_04050 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMMECHGA_04051 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NMMECHGA_04052 7.76e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
NMMECHGA_04053 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NMMECHGA_04054 1.25e-302 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NMMECHGA_04055 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
NMMECHGA_04056 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
NMMECHGA_04057 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NMMECHGA_04058 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
NMMECHGA_04059 6.05e-250 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NMMECHGA_04060 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
NMMECHGA_04061 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
NMMECHGA_04062 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NMMECHGA_04064 1.99e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NMMECHGA_04065 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NMMECHGA_04066 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMMECHGA_04067 1.72e-116 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NMMECHGA_04068 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
NMMECHGA_04069 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NMMECHGA_04070 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NMMECHGA_04071 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
NMMECHGA_04072 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NMMECHGA_04073 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
NMMECHGA_04074 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMMECHGA_04075 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NMMECHGA_04076 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
NMMECHGA_04077 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
NMMECHGA_04078 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
NMMECHGA_04079 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NMMECHGA_04080 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NMMECHGA_04081 2.01e-267 acdA - - I - - - acyl-CoA dehydrogenase
NMMECHGA_04082 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
NMMECHGA_04083 5.54e-286 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NMMECHGA_04084 4.68e-234 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NMMECHGA_04085 1.32e-57 ywjC - - - - - - -
NMMECHGA_04086 5.49e-124 ywjB - - H - - - RibD C-terminal domain
NMMECHGA_04087 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
NMMECHGA_04088 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMMECHGA_04089 2.06e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
NMMECHGA_04090 2.77e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
NMMECHGA_04091 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
NMMECHGA_04092 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NMMECHGA_04093 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
NMMECHGA_04094 1.84e-179 ywiC - - S - - - YwiC-like protein
NMMECHGA_04095 1.89e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
NMMECHGA_04096 3.44e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NMMECHGA_04097 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NMMECHGA_04098 4.64e-96 ywiB - - S - - - protein conserved in bacteria
NMMECHGA_04099 3.71e-12 - - - S - - - Bacteriocin subtilosin A
NMMECHGA_04100 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
NMMECHGA_04102 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NMMECHGA_04103 4.86e-297 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
NMMECHGA_04104 1.9e-273 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
NMMECHGA_04105 1.17e-315 - - - L - - - Peptidase, M16
NMMECHGA_04107 0.0 ywhL - - CO - - - amine dehydrogenase activity
NMMECHGA_04108 9.47e-275 ywhK - - CO - - - amine dehydrogenase activity
NMMECHGA_04109 1.32e-106 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NMMECHGA_04111 8.78e-37 - - - S - - - Aminoacyl-tRNA editing domain
NMMECHGA_04112 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NMMECHGA_04113 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NMMECHGA_04114 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NMMECHGA_04115 2.1e-64 - - - - - - - -
NMMECHGA_04116 5.51e-123 ywhD - - S - - - YwhD family
NMMECHGA_04117 7.75e-153 ywhC - - S - - - Peptidase family M50
NMMECHGA_04118 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
NMMECHGA_04119 1.76e-94 ywhA - - K - - - Transcriptional regulator
NMMECHGA_04120 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NMMECHGA_04122 1.21e-303 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
NMMECHGA_04123 1.28e-102 yffB - - K - - - Transcriptional regulator
NMMECHGA_04124 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
NMMECHGA_04125 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
NMMECHGA_04126 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
NMMECHGA_04127 5.39e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
NMMECHGA_04128 7.47e-203 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
NMMECHGA_04129 1.24e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NMMECHGA_04130 7.53e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_04131 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
NMMECHGA_04132 5.69e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
NMMECHGA_04133 3.93e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
NMMECHGA_04134 3.66e-296 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
NMMECHGA_04135 3.21e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
NMMECHGA_04136 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NMMECHGA_04137 3.14e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMMECHGA_04138 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NMMECHGA_04139 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NMMECHGA_04140 3.81e-275 ywfA - - EGP - - - -transporter
NMMECHGA_04141 7.08e-316 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NMMECHGA_04142 0.0 rocB - - E - - - arginine degradation protein
NMMECHGA_04143 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NMMECHGA_04144 1.49e-310 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NMMECHGA_04145 3.7e-101 - - - - - - - -
NMMECHGA_04146 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
NMMECHGA_04147 5.74e-205 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NMMECHGA_04148 1.51e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NMMECHGA_04149 7.45e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NMMECHGA_04150 4.04e-240 spsG - - M - - - Spore Coat
NMMECHGA_04151 4.64e-169 spsF - - M ko:K07257 - ko00000 Spore Coat
NMMECHGA_04152 1.13e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
NMMECHGA_04153 1.04e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
NMMECHGA_04154 3.73e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
NMMECHGA_04155 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
NMMECHGA_04156 1.57e-184 spsA - - M - - - Spore Coat
NMMECHGA_04157 1.54e-113 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NMMECHGA_04158 1.59e-78 ywdK - - S - - - small membrane protein
NMMECHGA_04159 1.86e-303 ywdJ - - F - - - Xanthine uracil
NMMECHGA_04160 9.23e-65 ywdI - - S - - - Family of unknown function (DUF5327)
NMMECHGA_04161 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NMMECHGA_04162 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NMMECHGA_04163 1.34e-191 ywdF - - S - - - Glycosyltransferase like family 2
NMMECHGA_04164 1.82e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NMMECHGA_04165 6.19e-39 ywdA - - - - - - -
NMMECHGA_04166 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NMMECHGA_04167 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NMMECHGA_04168 6.85e-179 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
NMMECHGA_04169 5.24e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NMMECHGA_04171 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NMMECHGA_04172 1.34e-235 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMMECHGA_04173 2.31e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
NMMECHGA_04174 5.14e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NMMECHGA_04175 2.23e-261 - - - S - - - Acetyltransferase
NMMECHGA_04176 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
NMMECHGA_04177 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NMMECHGA_04178 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NMMECHGA_04179 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NMMECHGA_04180 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NMMECHGA_04181 5.11e-49 ydaS - - S - - - membrane
NMMECHGA_04182 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NMMECHGA_04183 8.22e-289 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NMMECHGA_04184 3.33e-77 gtcA - - S - - - GtrA-like protein
NMMECHGA_04185 4.16e-159 ywcC - - K - - - transcriptional regulator
NMMECHGA_04187 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
NMMECHGA_04188 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMMECHGA_04189 1.21e-142 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NMMECHGA_04190 5.13e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
NMMECHGA_04191 1.98e-245 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
NMMECHGA_04192 8.64e-317 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
NMMECHGA_04193 1.22e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NMMECHGA_04194 3.12e-183 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NMMECHGA_04195 1.56e-202 ywbI - - K - - - Transcriptional regulator
NMMECHGA_04196 2.21e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NMMECHGA_04197 1.41e-142 ywbG - - M - - - effector of murein hydrolase
NMMECHGA_04198 4.31e-277 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
NMMECHGA_04199 3.13e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
NMMECHGA_04200 5e-274 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
NMMECHGA_04201 1.64e-86 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
NMMECHGA_04202 2.91e-94 - - - E - - - LysE type translocator
NMMECHGA_04203 1.04e-94 - - - S ko:K09190 - ko00000 YqcI/YcgG family
NMMECHGA_04204 1.24e-136 ywbB - - S - - - Protein of unknown function (DUF2711)
NMMECHGA_04205 4.09e-308 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMMECHGA_04206 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NMMECHGA_04207 3.4e-311 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NMMECHGA_04208 9.07e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NMMECHGA_04209 5.37e-216 gspA - - M - - - General stress
NMMECHGA_04210 2.46e-158 ywaF - - S - - - Integral membrane protein
NMMECHGA_04211 3.57e-114 ywaE - - K - - - Transcriptional regulator
NMMECHGA_04212 1.67e-292 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NMMECHGA_04213 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
NMMECHGA_04214 1.08e-115 - - - K - - - Helix-turn-helix XRE-family like proteins
NMMECHGA_04215 5.58e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NMMECHGA_04216 3.22e-164 - - - EGP - - - Permeases of the major facilitator superfamily
NMMECHGA_04217 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
NMMECHGA_04218 5.1e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
NMMECHGA_04219 1.27e-20 - - - S - - - D-Ala-teichoic acid biosynthesis protein
NMMECHGA_04220 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMMECHGA_04221 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
NMMECHGA_04222 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMMECHGA_04223 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NMMECHGA_04224 2.91e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NMMECHGA_04225 2.52e-262 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NMMECHGA_04226 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NMMECHGA_04227 6.85e-67 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NMMECHGA_04228 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMMECHGA_04229 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
NMMECHGA_04230 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NMMECHGA_04231 8.94e-28 yxzF - - - - - - -
NMMECHGA_04232 1.54e-143 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NMMECHGA_04233 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NMMECHGA_04234 3.76e-269 yxlH - - EGP - - - Major Facilitator Superfamily
NMMECHGA_04235 4.62e-178 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NMMECHGA_04236 8.18e-211 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_04237 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
NMMECHGA_04238 4.69e-39 - - - - - - - -
NMMECHGA_04239 7.55e-60 yxlC - - S - - - Family of unknown function (DUF5345)
NMMECHGA_04240 2.05e-121 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NMMECHGA_04241 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
NMMECHGA_04242 9.16e-203 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NMMECHGA_04243 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
NMMECHGA_04244 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
NMMECHGA_04245 8.19e-244 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
NMMECHGA_04246 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NMMECHGA_04247 2.67e-308 cimH - - C - - - COG3493 Na citrate symporter
NMMECHGA_04248 0.0 - - - O - - - Peptidase family M48
NMMECHGA_04250 2.51e-197 yxkH - - G - - - Polysaccharide deacetylase
NMMECHGA_04251 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NMMECHGA_04252 1.12e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
NMMECHGA_04253 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMMECHGA_04254 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NMMECHGA_04255 1.66e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
NMMECHGA_04256 2.11e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NMMECHGA_04257 2.68e-100 - - - S - - - Protein of unknown function (DUF1453)
NMMECHGA_04258 3.38e-259 - - - T - - - Signal transduction histidine kinase
NMMECHGA_04259 4.65e-149 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
NMMECHGA_04260 2.22e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NMMECHGA_04263 6.8e-110 yxjI - - S - - - LURP-one-related
NMMECHGA_04264 1.01e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
NMMECHGA_04265 1.49e-273 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
NMMECHGA_04266 1.6e-173 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NMMECHGA_04267 4.86e-150 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NMMECHGA_04268 2.69e-167 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NMMECHGA_04269 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
NMMECHGA_04270 9.86e-201 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
NMMECHGA_04271 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NMMECHGA_04272 7.26e-134 - - - T - - - Domain of unknown function (DUF4163)
NMMECHGA_04273 2.28e-63 yxiS - - - - - - -
NMMECHGA_04274 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NMMECHGA_04275 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NMMECHGA_04276 4.35e-184 bglS - - M - - - licheninase activity
NMMECHGA_04277 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NMMECHGA_04278 1.25e-141 - - - - - - - -
NMMECHGA_04279 4.43e-291 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
NMMECHGA_04280 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NMMECHGA_04281 3.37e-272 - - - E - - - GDSL-like Lipase/Acylhydrolase
NMMECHGA_04282 4.57e-71 - - - K - - - Transcriptional regulator PadR-like family
NMMECHGA_04283 3.26e-79 - - - S - - - Protein of unknown function (DUF2812)
NMMECHGA_04286 6.49e-55 yxiJ - - S - - - YxiJ-like protein
NMMECHGA_04287 3.23e-108 yxiI - - S - - - Protein of unknown function (DUF2716)
NMMECHGA_04288 2.52e-211 yxxF - - EG - - - EamA-like transporter family
NMMECHGA_04289 2.86e-162 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMMECHGA_04290 2.25e-157 - 1.14.11.45 - E ko:K20418 - ko00000,ko01000 2OG-Fe dioxygenase
NMMECHGA_04291 6.99e-94 yxiE - - T - - - Belongs to the universal stress protein A family
NMMECHGA_04292 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NMMECHGA_04293 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NMMECHGA_04294 8.25e-69 - - - - - - - -
NMMECHGA_04295 1.91e-272 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
NMMECHGA_04296 2.69e-52 yxiC - - S - - - Family of unknown function (DUF5344)
NMMECHGA_04297 6.24e-36 - - - S - - - Domain of unknown function (DUF5082)
NMMECHGA_04298 2.96e-64 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NMMECHGA_04299 4.76e-233 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
NMMECHGA_04300 7.83e-111 - - - S - - - GTP binding
NMMECHGA_04301 1.77e-95 - - - L - - - NgoFVII restriction endonuclease
NMMECHGA_04302 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NMMECHGA_04303 4.54e-13 - - - S - - - Oxidoreductase
NMMECHGA_04305 5.13e-16 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
NMMECHGA_04306 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NMMECHGA_04307 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
NMMECHGA_04308 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NMMECHGA_04309 1.06e-297 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
NMMECHGA_04310 1.89e-228 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NMMECHGA_04311 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NMMECHGA_04312 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
NMMECHGA_04313 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NMMECHGA_04314 3.38e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NMMECHGA_04315 3.5e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NMMECHGA_04316 1.51e-196 - - - S - - - Domain of Unknown Function (DUF1206)
NMMECHGA_04317 1.43e-251 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
NMMECHGA_04318 0.0 yxeQ - - S - - - MmgE/PrpD family
NMMECHGA_04319 2.47e-273 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
NMMECHGA_04320 1.67e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_04321 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NMMECHGA_04322 2.39e-183 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NMMECHGA_04323 2.46e-118 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMMECHGA_04324 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMMECHGA_04325 6.97e-240 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NMMECHGA_04326 1.34e-192 yxeH - - S - - - hydrolases of the HAD superfamily
NMMECHGA_04329 7.32e-42 yxeE - - - - - - -
NMMECHGA_04330 7.57e-28 yxeD - - - - - - -
NMMECHGA_04331 1.37e-90 - - - - - - - -
NMMECHGA_04332 8.63e-226 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NMMECHGA_04333 4.9e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
NMMECHGA_04334 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NMMECHGA_04335 8.64e-178 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NMMECHGA_04336 1.28e-229 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMMECHGA_04337 8.03e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMMECHGA_04338 9.47e-203 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NMMECHGA_04339 8e-194 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NMMECHGA_04340 2.65e-213 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
NMMECHGA_04341 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NMMECHGA_04342 1.99e-296 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
NMMECHGA_04343 3.51e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NMMECHGA_04344 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NMMECHGA_04345 3.52e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NMMECHGA_04346 4.9e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NMMECHGA_04347 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMMECHGA_04348 6.35e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NMMECHGA_04349 2.04e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
NMMECHGA_04351 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
NMMECHGA_04352 4.69e-116 - - - S - - - CGNR zinc finger
NMMECHGA_04353 1.34e-104 - - - T - - - HPP family
NMMECHGA_04354 2.06e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NMMECHGA_04355 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
NMMECHGA_04357 8.74e-195 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NMMECHGA_04358 5.01e-255 yxbF - - K - - - Bacterial regulatory proteins, tetR family
NMMECHGA_04359 6.6e-311 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NMMECHGA_04360 4.66e-31 yxaI - - S - - - membrane protein domain
NMMECHGA_04361 5.64e-134 yxaL - - S - - - PQQ-like domain
NMMECHGA_04362 1.54e-80 - - - S - - - Family of unknown function (DUF5391)
NMMECHGA_04363 4.03e-99 yxaI - - S - - - membrane protein domain
NMMECHGA_04364 5.33e-286 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
NMMECHGA_04365 4.77e-247 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
NMMECHGA_04366 3.91e-130 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NMMECHGA_04367 7.43e-256 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NMMECHGA_04368 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NMMECHGA_04369 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
NMMECHGA_04370 1.27e-152 yxaC - - M - - - effector of murein hydrolase
NMMECHGA_04371 1.58e-239 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
NMMECHGA_04372 8.83e-236 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NMMECHGA_04373 3.34e-159 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
NMMECHGA_04374 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NMMECHGA_04375 2.66e-291 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
NMMECHGA_04376 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NMMECHGA_04377 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
NMMECHGA_04378 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
NMMECHGA_04379 1.11e-237 - - - S - - - Polysaccharide pyruvyl transferase
NMMECHGA_04380 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NMMECHGA_04381 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NMMECHGA_04382 1.42e-157 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
NMMECHGA_04383 8.07e-264 - - - I - - - acetylesterase activity
NMMECHGA_04384 2.44e-139 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NMMECHGA_04385 9.28e-131 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NMMECHGA_04386 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
NMMECHGA_04387 4.53e-280 - - - - - - - -
NMMECHGA_04388 2.68e-178 - - - U - - - Protein of unknown function DUF262
NMMECHGA_04389 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NMMECHGA_04391 5.92e-83 - - - - - - - -
NMMECHGA_04392 5.2e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NMMECHGA_04394 5.5e-42 yycQ - - S - - - Protein of unknown function (DUF2651)
NMMECHGA_04395 2.17e-266 yycP - - - - - - -
NMMECHGA_04396 2.67e-166 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NMMECHGA_04397 1.83e-111 yycN - - K - - - Acetyltransferase
NMMECHGA_04398 8.7e-239 - - - S - - - aspartate phosphatase
NMMECHGA_04400 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NMMECHGA_04401 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NMMECHGA_04402 2.89e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
NMMECHGA_04403 5.82e-20 - - - - - - - -
NMMECHGA_04404 3.42e-119 - - - - - - - -
NMMECHGA_04405 6.81e-19 - - - S - - - Sporulation delaying protein SdpA
NMMECHGA_04406 3.95e-87 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NMMECHGA_04407 5.02e-55 sdpR - - K - - - transcriptional
NMMECHGA_04409 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NMMECHGA_04410 9.16e-215 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NMMECHGA_04411 2.36e-122 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
NMMECHGA_04412 2.31e-98 - - - S - - - Peptidase propeptide and YPEB domain
NMMECHGA_04413 8.73e-42 - - - S - - - Peptidase propeptide and YPEB domain
NMMECHGA_04414 1.56e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMMECHGA_04415 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NMMECHGA_04416 2.83e-199 yycI - - S - - - protein conserved in bacteria
NMMECHGA_04417 0.0 yycH - - S - - - protein conserved in bacteria
NMMECHGA_04418 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NMMECHGA_04419 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMMECHGA_04424 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NMMECHGA_04425 5.47e-98 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMMECHGA_04426 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NMMECHGA_04427 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
NMMECHGA_04429 1.89e-22 yycC - - K - - - YycC-like protein
NMMECHGA_04430 9.87e-282 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
NMMECHGA_04431 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NMMECHGA_04432 7.85e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NMMECHGA_04433 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NMMECHGA_04434 2.13e-204 yybS - - S - - - membrane
NMMECHGA_04436 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
NMMECHGA_04437 1.11e-88 yybR - - K - - - Transcriptional regulator
NMMECHGA_04438 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
NMMECHGA_04439 7.41e-80 - - - - - - - -
NMMECHGA_04441 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NMMECHGA_04442 5.1e-141 - - - K - - - TipAS antibiotic-recognition domain
NMMECHGA_04443 6.85e-182 - - - - - - - -
NMMECHGA_04444 1.23e-87 - - - S - - - SnoaL-like domain
NMMECHGA_04445 9.3e-141 yybG - - S - - - Pentapeptide repeat-containing protein
NMMECHGA_04446 2.25e-265 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NMMECHGA_04447 5.12e-211 yybE - - K - - - Transcriptional regulator
NMMECHGA_04448 1.04e-99 yjcF - - S - - - Acetyltransferase (GNAT) domain
NMMECHGA_04449 4.25e-98 yybC - - - - - - -
NMMECHGA_04450 2.52e-163 - - - S - - - Metallo-beta-lactamase superfamily
NMMECHGA_04451 4.54e-100 yybA - - K - - - transcriptional
NMMECHGA_04452 5.09e-91 yjcF - - S - - - Acetyltransferase (GNAT) domain
NMMECHGA_04453 8.63e-125 yyaS - - S ko:K07149 - ko00000 Membrane
NMMECHGA_04454 4.7e-120 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
NMMECHGA_04455 1.5e-85 - - - S - - - YjbR
NMMECHGA_04456 4.99e-136 yyaP - - H - - - RibD C-terminal domain
NMMECHGA_04457 2.32e-313 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
NMMECHGA_04458 7.75e-88 - - - K - - - MerR HTH family regulatory protein
NMMECHGA_04459 3.84e-205 - - - EG - - - EamA-like transporter family
NMMECHGA_04460 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
NMMECHGA_04461 4.06e-213 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
NMMECHGA_04462 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
NMMECHGA_04463 6.32e-128 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
NMMECHGA_04464 1.45e-89 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMMECHGA_04465 5.63e-226 ccpB - - K - - - Transcriptional regulator
NMMECHGA_04466 1.63e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NMMECHGA_04467 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NMMECHGA_04468 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NMMECHGA_04469 8.33e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NMMECHGA_04470 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NMMECHGA_04471 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NMMECHGA_04472 7.41e-45 yyzM - - S - - - protein conserved in bacteria
NMMECHGA_04473 5.34e-227 yyaD - - S - - - Membrane
NMMECHGA_04474 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
NMMECHGA_04475 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NMMECHGA_04476 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
NMMECHGA_04477 9.26e-98 - - - S - - - Bacterial PH domain
NMMECHGA_04478 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NMMECHGA_04479 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NMMECHGA_04480 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NMMECHGA_04481 1.81e-316 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NMMECHGA_04482 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
NMMECHGA_04483 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NMMECHGA_04484 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NMMECHGA_04487 5.55e-94 - - - K - - - Transcriptional regulator
NMMECHGA_04490 7.83e-174 - - - S - - - COG0457 FOG TPR repeat
NMMECHGA_04491 4.56e-224 - - - L - - - Replication protein

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)