ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
LKCGKMCK_00001 5.55e-301 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LKCGKMCK_00002 1.71e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LKCGKMCK_00003 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
LKCGKMCK_00004 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LKCGKMCK_00005 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
LKCGKMCK_00006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LKCGKMCK_00007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LKCGKMCK_00008 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LKCGKMCK_00011 4.5e-234 yaaC - - S - - - YaaC-like Protein
LKCGKMCK_00012 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LKCGKMCK_00013 2.81e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LKCGKMCK_00014 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LKCGKMCK_00015 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LKCGKMCK_00016 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LKCGKMCK_00018 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
LKCGKMCK_00019 2.43e-150 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
LKCGKMCK_00020 7.7e-278 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
LKCGKMCK_00021 1.44e-127 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
LKCGKMCK_00022 1.55e-110 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LKCGKMCK_00023 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LKCGKMCK_00024 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LKCGKMCK_00025 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LKCGKMCK_00026 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
LKCGKMCK_00027 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
LKCGKMCK_00028 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LKCGKMCK_00031 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
LKCGKMCK_00032 3.28e-133 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LKCGKMCK_00033 5.05e-260 yaaN - - P - - - Belongs to the TelA family
LKCGKMCK_00034 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
LKCGKMCK_00035 2.82e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LKCGKMCK_00036 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
LKCGKMCK_00037 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
LKCGKMCK_00038 2.42e-236 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LKCGKMCK_00039 1.1e-189 yaaT - - S - - - stage 0 sporulation protein
LKCGKMCK_00040 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
LKCGKMCK_00041 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
LKCGKMCK_00042 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
LKCGKMCK_00043 7.26e-208 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LKCGKMCK_00044 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
LKCGKMCK_00045 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LKCGKMCK_00046 5.05e-185 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
LKCGKMCK_00047 1.91e-283 yabE - - T - - - protein conserved in bacteria
LKCGKMCK_00048 1.05e-127 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LKCGKMCK_00049 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LKCGKMCK_00050 6.69e-200 yabG - - S ko:K06436 - ko00000 peptidase
LKCGKMCK_00051 5.32e-53 veg - - S - - - protein conserved in bacteria
LKCGKMCK_00052 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
LKCGKMCK_00053 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LKCGKMCK_00054 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
LKCGKMCK_00055 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
LKCGKMCK_00056 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LKCGKMCK_00057 9e-310 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LKCGKMCK_00058 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LKCGKMCK_00059 1.45e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LKCGKMCK_00060 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LKCGKMCK_00061 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
LKCGKMCK_00062 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LKCGKMCK_00063 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
LKCGKMCK_00064 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKCGKMCK_00065 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LKCGKMCK_00066 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LKCGKMCK_00067 1.91e-66 yabP - - S - - - Sporulation protein YabP
LKCGKMCK_00068 2.21e-139 yabQ - - S - - - spore cortex biosynthesis protein
LKCGKMCK_00069 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
LKCGKMCK_00070 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
LKCGKMCK_00073 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
LKCGKMCK_00074 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LKCGKMCK_00075 1.25e-238 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
LKCGKMCK_00076 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LKCGKMCK_00077 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
LKCGKMCK_00078 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LKCGKMCK_00079 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LKCGKMCK_00080 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LKCGKMCK_00081 6.68e-196 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
LKCGKMCK_00082 3.77e-218 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LKCGKMCK_00083 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LKCGKMCK_00084 1.03e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
LKCGKMCK_00085 2.27e-216 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
LKCGKMCK_00086 3.32e-205 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LKCGKMCK_00087 2.78e-82 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LKCGKMCK_00088 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LKCGKMCK_00089 1.81e-41 yazB - - K - - - transcriptional
LKCGKMCK_00090 7.88e-244 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LKCGKMCK_00091 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
LKCGKMCK_00092 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LKCGKMCK_00102 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LKCGKMCK_00103 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
LKCGKMCK_00104 2.76e-65 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
LKCGKMCK_00105 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LKCGKMCK_00106 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
LKCGKMCK_00107 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LKCGKMCK_00108 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LKCGKMCK_00109 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
LKCGKMCK_00110 1.82e-162 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LKCGKMCK_00111 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LKCGKMCK_00112 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LKCGKMCK_00113 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
LKCGKMCK_00114 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LKCGKMCK_00115 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LKCGKMCK_00116 4.29e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LKCGKMCK_00117 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
LKCGKMCK_00118 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
LKCGKMCK_00119 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LKCGKMCK_00120 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LKCGKMCK_00121 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LKCGKMCK_00122 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LKCGKMCK_00123 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LKCGKMCK_00124 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LKCGKMCK_00125 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
LKCGKMCK_00126 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKCGKMCK_00127 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKCGKMCK_00128 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
LKCGKMCK_00129 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LKCGKMCK_00130 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LKCGKMCK_00131 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LKCGKMCK_00132 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LKCGKMCK_00133 8.78e-238 ybaC - - S - - - Alpha/beta hydrolase family
LKCGKMCK_00134 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
LKCGKMCK_00135 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LKCGKMCK_00136 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
LKCGKMCK_00137 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LKCGKMCK_00138 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LKCGKMCK_00139 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LKCGKMCK_00140 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LKCGKMCK_00141 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LKCGKMCK_00142 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LKCGKMCK_00143 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
LKCGKMCK_00144 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LKCGKMCK_00145 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LKCGKMCK_00146 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LKCGKMCK_00147 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LKCGKMCK_00148 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LKCGKMCK_00149 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LKCGKMCK_00150 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LKCGKMCK_00151 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LKCGKMCK_00152 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LKCGKMCK_00153 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
LKCGKMCK_00154 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
LKCGKMCK_00155 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LKCGKMCK_00156 6.17e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LKCGKMCK_00157 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
LKCGKMCK_00158 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LKCGKMCK_00159 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
LKCGKMCK_00160 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LKCGKMCK_00161 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LKCGKMCK_00162 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKCGKMCK_00163 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
LKCGKMCK_00164 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKCGKMCK_00165 2.69e-197 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKCGKMCK_00166 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKCGKMCK_00167 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LKCGKMCK_00168 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LKCGKMCK_00169 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
LKCGKMCK_00170 2.14e-186 ybaJ - - Q - - - Methyltransferase domain
LKCGKMCK_00171 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
LKCGKMCK_00172 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LKCGKMCK_00173 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LKCGKMCK_00174 1.04e-122 gerD - - - ko:K06294 - ko00000 -
LKCGKMCK_00175 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
LKCGKMCK_00176 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
LKCGKMCK_00177 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LKCGKMCK_00184 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LKCGKMCK_00185 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LKCGKMCK_00186 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
LKCGKMCK_00188 3.47e-205 ybaS - - S - - - Na -dependent transporter
LKCGKMCK_00189 4.01e-184 ybbA - - S ko:K07017 - ko00000 Putative esterase
LKCGKMCK_00190 3.51e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKCGKMCK_00191 2.88e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKCGKMCK_00192 9.23e-219 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
LKCGKMCK_00193 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
LKCGKMCK_00194 3.6e-306 ybbC - - S - - - protein conserved in bacteria
LKCGKMCK_00195 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
LKCGKMCK_00196 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
LKCGKMCK_00197 7.29e-304 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKCGKMCK_00198 3.82e-194 ybbH - - K - - - transcriptional
LKCGKMCK_00199 4.04e-211 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LKCGKMCK_00200 1.55e-114 ybbJ - - J - - - acetyltransferase
LKCGKMCK_00201 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
LKCGKMCK_00207 1.6e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LKCGKMCK_00208 2.73e-152 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LKCGKMCK_00209 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LKCGKMCK_00210 4.16e-292 ybbR - - S - - - protein conserved in bacteria
LKCGKMCK_00211 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LKCGKMCK_00212 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LKCGKMCK_00213 3.67e-227 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LKCGKMCK_00214 2.25e-157 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
LKCGKMCK_00215 4.49e-130 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LKCGKMCK_00216 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LKCGKMCK_00217 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
LKCGKMCK_00218 2.51e-125 ybcF - - P - - - carbonic anhydrase
LKCGKMCK_00219 5.59e-64 - - - - - - - -
LKCGKMCK_00220 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
LKCGKMCK_00221 9.45e-67 - - - K - - - Helix-turn-helix domain
LKCGKMCK_00222 1.14e-258 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
LKCGKMCK_00224 7.24e-304 - - - J - - - 4Fe-4S single cluster domain
LKCGKMCK_00225 0.0 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
LKCGKMCK_00226 8.07e-174 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LKCGKMCK_00227 3.99e-313 skfF - - S - - - ABC transporter
LKCGKMCK_00228 3.88e-118 - - - C - - - HEAT repeats
LKCGKMCK_00229 5.88e-103 - - - CO - - - Thioredoxin-like domain
LKCGKMCK_00230 8.07e-233 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LKCGKMCK_00231 2.93e-159 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
LKCGKMCK_00232 4.12e-221 - - - T - - - His Kinase A (phospho-acceptor) domain
LKCGKMCK_00234 2.49e-181 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
LKCGKMCK_00235 6.61e-196 ybdN - - - - - - -
LKCGKMCK_00236 1.19e-278 ybdO - - S - - - Domain of unknown function (DUF4885)
LKCGKMCK_00237 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LKCGKMCK_00238 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
LKCGKMCK_00239 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
LKCGKMCK_00240 3.86e-195 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
LKCGKMCK_00241 9.97e-317 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
LKCGKMCK_00242 1.11e-54 ybyB - - - - - - -
LKCGKMCK_00243 0.0 ybeC - - E - - - amino acid
LKCGKMCK_00244 7.3e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
LKCGKMCK_00245 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
LKCGKMCK_00246 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
LKCGKMCK_00247 8.93e-220 ybfA - - K - - - FR47-like protein
LKCGKMCK_00248 2.36e-287 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
LKCGKMCK_00250 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
LKCGKMCK_00251 5.27e-208 ybfH - - EG - - - EamA-like transporter family
LKCGKMCK_00252 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
LKCGKMCK_00253 5.85e-274 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LKCGKMCK_00254 5.04e-230 mpr - - M - - - Belongs to the peptidase S1B family
LKCGKMCK_00256 2.02e-216 - - - S - - - Alpha/beta hydrolase family
LKCGKMCK_00257 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LKCGKMCK_00258 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
LKCGKMCK_00259 4.33e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
LKCGKMCK_00260 2.33e-61 ybfN - - - - - - -
LKCGKMCK_00261 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
LKCGKMCK_00262 5.14e-214 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_00263 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
LKCGKMCK_00264 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKCGKMCK_00265 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKCGKMCK_00266 7.72e-177 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LKCGKMCK_00267 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
LKCGKMCK_00269 9.84e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LKCGKMCK_00270 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LKCGKMCK_00271 2.23e-234 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
LKCGKMCK_00272 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
LKCGKMCK_00273 9.16e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
LKCGKMCK_00274 3.55e-294 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKCGKMCK_00275 1.72e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
LKCGKMCK_00276 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
LKCGKMCK_00277 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LKCGKMCK_00278 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LKCGKMCK_00279 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LKCGKMCK_00280 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
LKCGKMCK_00281 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
LKCGKMCK_00282 4.64e-227 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
LKCGKMCK_00283 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
LKCGKMCK_00284 1.87e-220 eamA1 - - EG - - - spore germination
LKCGKMCK_00285 6.64e-162 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKCGKMCK_00286 1.66e-218 ycbM - - T - - - Histidine kinase
LKCGKMCK_00287 1.66e-216 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_00288 4.25e-150 - - - S - - - ABC-2 family transporter protein
LKCGKMCK_00289 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
LKCGKMCK_00290 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
LKCGKMCK_00291 4.66e-175 ycbR - - T - - - vWA found in TerF C terminus
LKCGKMCK_00292 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
LKCGKMCK_00293 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LKCGKMCK_00294 7.6e-160 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LKCGKMCK_00295 2.52e-156 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LKCGKMCK_00296 3.48e-268 ycbU - - E - - - Selenocysteine lyase
LKCGKMCK_00297 2.87e-308 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
LKCGKMCK_00298 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
LKCGKMCK_00299 8.74e-260 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LKCGKMCK_00300 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
LKCGKMCK_00301 4.32e-78 - - - S - - - RDD family
LKCGKMCK_00302 2.49e-255 yccF - - K ko:K07039 - ko00000 SEC-C motif
LKCGKMCK_00303 9.56e-217 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LKCGKMCK_00304 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LKCGKMCK_00305 5.41e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
LKCGKMCK_00306 9.75e-258 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LKCGKMCK_00307 5.83e-223 yccK - - C - - - Aldo keto reductase
LKCGKMCK_00308 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
LKCGKMCK_00309 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LKCGKMCK_00310 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LKCGKMCK_00311 3.91e-125 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
LKCGKMCK_00312 1.42e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
LKCGKMCK_00313 5.87e-181 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
LKCGKMCK_00314 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LKCGKMCK_00315 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LKCGKMCK_00316 1.99e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LKCGKMCK_00317 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LKCGKMCK_00318 9.18e-242 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKCGKMCK_00319 2.64e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
LKCGKMCK_00320 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
LKCGKMCK_00321 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
LKCGKMCK_00322 4.1e-176 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
LKCGKMCK_00323 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
LKCGKMCK_00324 2.96e-245 yceH - - P - - - Belongs to the TelA family
LKCGKMCK_00325 2.32e-279 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
LKCGKMCK_00326 1.17e-267 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
LKCGKMCK_00327 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LKCGKMCK_00328 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
LKCGKMCK_00329 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
LKCGKMCK_00330 2.01e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
LKCGKMCK_00331 2.5e-279 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
LKCGKMCK_00332 0.0 ycgA - - S - - - Membrane
LKCGKMCK_00333 1.25e-127 ycgB - - - - - - -
LKCGKMCK_00334 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
LKCGKMCK_00335 2.06e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LKCGKMCK_00336 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LKCGKMCK_00337 0.0 mdr - - EGP - - - the major facilitator superfamily
LKCGKMCK_00338 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKCGKMCK_00339 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
LKCGKMCK_00340 1.85e-195 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
LKCGKMCK_00341 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LKCGKMCK_00342 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
LKCGKMCK_00343 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LKCGKMCK_00344 1.31e-140 tmrB - - S - - - AAA domain
LKCGKMCK_00345 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LKCGKMCK_00346 1.29e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
LKCGKMCK_00347 2.05e-230 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
LKCGKMCK_00348 1.15e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
LKCGKMCK_00349 7.76e-187 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
LKCGKMCK_00350 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
LKCGKMCK_00351 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
LKCGKMCK_00352 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKCGKMCK_00353 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
LKCGKMCK_00354 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
LKCGKMCK_00355 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
LKCGKMCK_00356 4.74e-209 ycgS - - I - - - alpha/beta hydrolase fold
LKCGKMCK_00357 8.9e-247 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
LKCGKMCK_00358 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
LKCGKMCK_00359 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
LKCGKMCK_00360 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LKCGKMCK_00361 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LKCGKMCK_00362 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
LKCGKMCK_00363 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
LKCGKMCK_00364 1.05e-222 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
LKCGKMCK_00365 2.56e-141 - - - M - - - ErfK YbiS YcfS YnhG
LKCGKMCK_00366 6.78e-291 yciC - - S - - - GTPases (G3E family)
LKCGKMCK_00367 2.99e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LKCGKMCK_00368 3.76e-187 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
LKCGKMCK_00371 5.95e-101 yckC - - S - - - membrane
LKCGKMCK_00372 3.53e-69 yckD - - S - - - Protein of unknown function (DUF2680)
LKCGKMCK_00373 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LKCGKMCK_00374 7.06e-93 nin - - S - - - Competence protein J (ComJ)
LKCGKMCK_00375 4.78e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
LKCGKMCK_00376 6.52e-269 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LKCGKMCK_00377 1.38e-127 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
LKCGKMCK_00378 2.39e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
LKCGKMCK_00379 6.05e-86 hxlR - - K - - - transcriptional
LKCGKMCK_00380 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKCGKMCK_00381 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKCGKMCK_00382 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
LKCGKMCK_00383 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
LKCGKMCK_00384 1.38e-291 - - - EGP - - - Major Facilitator Superfamily
LKCGKMCK_00385 1.61e-126 - - - S - - - YcxB-like protein
LKCGKMCK_00386 1.77e-209 ycxC - - EG - - - EamA-like transporter family
LKCGKMCK_00387 0.0 ycxD - - K - - - GntR family transcriptional regulator
LKCGKMCK_00388 1.37e-144 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
LKCGKMCK_00389 3.04e-148 yczE - - S ko:K07149 - ko00000 membrane
LKCGKMCK_00390 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LKCGKMCK_00391 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LKCGKMCK_00392 1.5e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LKCGKMCK_00393 9.2e-210 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
LKCGKMCK_00394 2.33e-142 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LKCGKMCK_00395 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
LKCGKMCK_00396 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
LKCGKMCK_00397 3.05e-109 yclD - - - - - - -
LKCGKMCK_00398 5.12e-207 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
LKCGKMCK_00399 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
LKCGKMCK_00400 0.0 yclG - - M - - - Pectate lyase superfamily protein
LKCGKMCK_00402 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
LKCGKMCK_00403 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
LKCGKMCK_00404 2.29e-254 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
LKCGKMCK_00405 2.05e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LKCGKMCK_00406 5.59e-280 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
LKCGKMCK_00407 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKCGKMCK_00408 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LKCGKMCK_00409 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LKCGKMCK_00411 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LKCGKMCK_00412 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LKCGKMCK_00413 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LKCGKMCK_00414 5.42e-206 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKCGKMCK_00415 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKCGKMCK_00416 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_00417 4.98e-223 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
LKCGKMCK_00418 0.0 ycnB - - EGP - - - the major facilitator superfamily
LKCGKMCK_00419 1.76e-199 ycnC - - K - - - Transcriptional regulator
LKCGKMCK_00420 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LKCGKMCK_00421 1.68e-60 ycnE - - S - - - Monooxygenase
LKCGKMCK_00422 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LKCGKMCK_00423 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKCGKMCK_00424 2.4e-313 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LKCGKMCK_00425 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LKCGKMCK_00426 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
LKCGKMCK_00427 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKCGKMCK_00428 1.07e-138 ycnI - - S - - - protein conserved in bacteria
LKCGKMCK_00429 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
LKCGKMCK_00430 5.18e-139 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LKCGKMCK_00431 1.34e-74 - - - - - - - -
LKCGKMCK_00432 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
LKCGKMCK_00433 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
LKCGKMCK_00434 3.77e-269 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
LKCGKMCK_00435 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
LKCGKMCK_00437 6.21e-97 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LKCGKMCK_00438 2.64e-147 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
LKCGKMCK_00439 2.29e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
LKCGKMCK_00441 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
LKCGKMCK_00442 9.39e-182 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
LKCGKMCK_00443 2.78e-273 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
LKCGKMCK_00444 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
LKCGKMCK_00445 5.04e-173 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
LKCGKMCK_00446 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
LKCGKMCK_00447 3.8e-171 kipR - - K - - - Transcriptional regulator
LKCGKMCK_00448 4.18e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
LKCGKMCK_00450 7.67e-66 yczJ - - S - - - biosynthesis
LKCGKMCK_00451 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
LKCGKMCK_00452 3.26e-224 ycsN - - S - - - Oxidoreductase
LKCGKMCK_00453 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
LKCGKMCK_00454 0.0 ydaB - - IQ - - - acyl-CoA ligase
LKCGKMCK_00455 6.05e-129 ydaC - - Q - - - Methyltransferase domain
LKCGKMCK_00456 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKCGKMCK_00457 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
LKCGKMCK_00458 6.6e-134 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LKCGKMCK_00459 5.24e-101 ydaG - - S - - - general stress protein
LKCGKMCK_00460 1.31e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
LKCGKMCK_00461 1.88e-62 ydzA - - EGP - - - Domain of unknown function (DUF3817)
LKCGKMCK_00462 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
LKCGKMCK_00463 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LKCGKMCK_00464 3.08e-267 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
LKCGKMCK_00465 1.14e-195 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
LKCGKMCK_00466 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
LKCGKMCK_00467 1.93e-304 ydaM - - M - - - Glycosyl transferase family group 2
LKCGKMCK_00468 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
LKCGKMCK_00469 0.0 ydaO - - E - - - amino acid
LKCGKMCK_00470 3.75e-103 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
LKCGKMCK_00471 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LKCGKMCK_00472 2.14e-53 - - - - - - - -
LKCGKMCK_00473 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LKCGKMCK_00474 1.67e-42 ydaS - - S - - - membrane
LKCGKMCK_00475 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
LKCGKMCK_00476 1.06e-190 ydbA - - P - - - EcsC protein family
LKCGKMCK_00477 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
LKCGKMCK_00478 7.58e-79 ydbB - - G - - - Cupin domain
LKCGKMCK_00479 5.41e-84 ydbC - - S - - - Domain of unknown function (DUF4937
LKCGKMCK_00480 1.35e-198 ydbD - - P ko:K07217 - ko00000 Catalase
LKCGKMCK_00481 3.66e-253 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LKCGKMCK_00482 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LKCGKMCK_00483 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
LKCGKMCK_00484 4.43e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKCGKMCK_00485 3.25e-231 ydbI - - S - - - AI-2E family transporter
LKCGKMCK_00486 2.28e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_00487 7.34e-160 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LKCGKMCK_00488 9.32e-70 ydbL - - - - - - -
LKCGKMCK_00489 1.83e-280 ydbM - - I - - - acyl-CoA dehydrogenase
LKCGKMCK_00490 1.49e-26 - - - S - - - Fur-regulated basic protein B
LKCGKMCK_00492 1.91e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LKCGKMCK_00493 4.19e-75 ydbP - - CO - - - Thioredoxin
LKCGKMCK_00494 3.07e-258 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
LKCGKMCK_00495 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LKCGKMCK_00496 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LKCGKMCK_00497 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
LKCGKMCK_00498 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
LKCGKMCK_00499 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
LKCGKMCK_00500 1.95e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LKCGKMCK_00501 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
LKCGKMCK_00502 5.29e-284 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LKCGKMCK_00503 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LKCGKMCK_00504 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
LKCGKMCK_00505 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
LKCGKMCK_00506 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
LKCGKMCK_00507 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LKCGKMCK_00508 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
LKCGKMCK_00509 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
LKCGKMCK_00510 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LKCGKMCK_00511 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKCGKMCK_00512 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
LKCGKMCK_00516 1.32e-106 ydcG - - S - - - EVE domain
LKCGKMCK_00517 1.54e-101 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKCGKMCK_00518 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
LKCGKMCK_00519 1.93e-110 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
LKCGKMCK_00527 2.43e-241 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKCGKMCK_00528 8.15e-94 lrpA - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
LKCGKMCK_00529 2.17e-102 lrpB - - K ko:K03719 - ko00000,ko03000,ko03036 transcriptional
LKCGKMCK_00530 1.62e-128 yddQ - - Q - - - Isochorismatase family
LKCGKMCK_00531 1.34e-184 yddR - - S - - - Zn-dependent hydrolases of the beta-lactamase fold
LKCGKMCK_00532 3.35e-288 ydeG3 - - EGP - - - Major Facilitator Superfamily
LKCGKMCK_00537 4.24e-146 ydeA - - S - - - DJ-1/PfpI family
LKCGKMCK_00538 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
LKCGKMCK_00539 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
LKCGKMCK_00540 2.47e-47 ydzE - - EG - - - spore germination
LKCGKMCK_00541 3.23e-215 - - - K - - - AraC-like ligand binding domain
LKCGKMCK_00542 4.99e-224 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LKCGKMCK_00543 2.87e-213 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
LKCGKMCK_00544 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKCGKMCK_00545 1.19e-280 ydeG - - EGP - - - Major facilitator superfamily
LKCGKMCK_00546 4.76e-72 ydeH - - - - - - -
LKCGKMCK_00547 1.26e-138 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
LKCGKMCK_00548 6.11e-150 - - - - - - - -
LKCGKMCK_00549 4.66e-197 ydeK - - EG - - - -transporter
LKCGKMCK_00550 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKCGKMCK_00551 3.68e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
LKCGKMCK_00552 8.6e-138 - - - S ko:K07002 - ko00000 Serine hydrolase
LKCGKMCK_00553 1.33e-77 - - - K - - - HxlR-like helix-turn-helix
LKCGKMCK_00554 1.68e-196 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LKCGKMCK_00555 5.03e-91 ydeP - - K - - - Transcriptional regulator
LKCGKMCK_00556 2.44e-142 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
LKCGKMCK_00557 1.51e-261 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
LKCGKMCK_00558 3.74e-136 ydeS - - K - - - Transcriptional regulator
LKCGKMCK_00559 2.56e-76 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
LKCGKMCK_00560 9.07e-297 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LKCGKMCK_00561 8.05e-191 - - - J - - - GNAT acetyltransferase
LKCGKMCK_00562 3.05e-207 - - - EG - - - EamA-like transporter family
LKCGKMCK_00563 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKCGKMCK_00564 5.97e-151 ydfE - - S - - - Flavin reductase like domain
LKCGKMCK_00565 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LKCGKMCK_00566 1.37e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LKCGKMCK_00568 4.11e-253 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKCGKMCK_00569 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKCGKMCK_00570 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
LKCGKMCK_00571 9.73e-226 - - - S - - - Alpha/beta hydrolase family
LKCGKMCK_00572 6.79e-152 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
LKCGKMCK_00573 2.13e-189 - - - K - - - Bacterial transcription activator, effector binding domain
LKCGKMCK_00574 3.15e-200 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LKCGKMCK_00575 3.45e-145 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
LKCGKMCK_00576 9.49e-239 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LKCGKMCK_00577 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
LKCGKMCK_00578 9.63e-77 ydfQ - - CO - - - Thioredoxin
LKCGKMCK_00579 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
LKCGKMCK_00580 5.33e-39 - - - - - - - -
LKCGKMCK_00582 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
LKCGKMCK_00583 4.44e-160 ydfS - - S - - - Protein of unknown function (DUF421)
LKCGKMCK_00584 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LKCGKMCK_00585 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
LKCGKMCK_00586 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
LKCGKMCK_00587 7.86e-132 ydgC - - K - - - Bacterial regulatory proteins, tetR family
LKCGKMCK_00588 3.47e-71 - - - S - - - DoxX-like family
LKCGKMCK_00589 2.49e-114 yycN - - K - - - Acetyltransferase
LKCGKMCK_00590 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
LKCGKMCK_00591 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LKCGKMCK_00592 5.09e-119 - - - S - - - DinB family
LKCGKMCK_00593 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKCGKMCK_00594 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
LKCGKMCK_00595 6.42e-147 ydgI - - C - - - nitroreductase
LKCGKMCK_00596 1.15e-90 - - - K - - - Winged helix DNA-binding domain
LKCGKMCK_00597 5.97e-267 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
LKCGKMCK_00598 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
LKCGKMCK_00599 5.24e-158 ydhC - - K - - - FCD
LKCGKMCK_00600 8.92e-310 ydhD - - M - - - Glycosyl hydrolase
LKCGKMCK_00601 9.61e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LKCGKMCK_00602 7.71e-166 - - - - - - - -
LKCGKMCK_00603 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
LKCGKMCK_00604 9.93e-91 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
LKCGKMCK_00606 1.43e-112 - - - K - - - Acetyltransferase (GNAT) domain
LKCGKMCK_00607 1.25e-236 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LKCGKMCK_00608 4.01e-130 ydhK - - M - - - Protein of unknown function (DUF1541)
LKCGKMCK_00609 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
LKCGKMCK_00610 7.97e-65 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKCGKMCK_00611 6.09e-70 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKCGKMCK_00612 2.27e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKCGKMCK_00613 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LKCGKMCK_00614 1.9e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
LKCGKMCK_00615 9.28e-219 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
LKCGKMCK_00616 1.93e-244 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LKCGKMCK_00617 3.49e-273 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
LKCGKMCK_00618 1.12e-98 ydhU - - P ko:K07217 - ko00000 Catalase
LKCGKMCK_00619 7.94e-22 ydhU - - P ko:K07217 - ko00000 Manganese containing catalase
LKCGKMCK_00622 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LKCGKMCK_00625 3.06e-237 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LKCGKMCK_00626 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
LKCGKMCK_00627 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
LKCGKMCK_00628 1.71e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LKCGKMCK_00629 1.63e-241 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LKCGKMCK_00630 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
LKCGKMCK_00631 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LKCGKMCK_00632 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LKCGKMCK_00633 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LKCGKMCK_00634 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LKCGKMCK_00635 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
LKCGKMCK_00636 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
LKCGKMCK_00637 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LKCGKMCK_00638 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LKCGKMCK_00640 6.93e-88 - - - KL ko:K06919 - ko00000 Phage plasmid primase P4 family
LKCGKMCK_00641 0.0 dcm 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
LKCGKMCK_00642 1.43e-297 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
LKCGKMCK_00644 3.67e-254 - - - V - - - AAA domain (dynein-related subfamily)
LKCGKMCK_00645 0.0 - - - J - - - LlaJI restriction endonuclease
LKCGKMCK_00646 3.73e-11 ydjC - - S - - - Abhydrolase domain containing 18
LKCGKMCK_00647 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
LKCGKMCK_00648 1.06e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
LKCGKMCK_00649 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
LKCGKMCK_00650 5.39e-224 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
LKCGKMCK_00651 5.36e-148 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
LKCGKMCK_00652 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LKCGKMCK_00653 3.96e-177 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
LKCGKMCK_00654 1.79e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
LKCGKMCK_00655 1.37e-248 - - - S - - - Ion transport 2 domain protein
LKCGKMCK_00656 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LKCGKMCK_00657 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
LKCGKMCK_00658 1.79e-84 ydjM - - M - - - Lytic transglycolase
LKCGKMCK_00659 3.76e-213 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
LKCGKMCK_00661 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
LKCGKMCK_00662 3.21e-205 - - - I - - - Alpha/beta hydrolase family
LKCGKMCK_00663 1.9e-233 yeaA - - S - - - Protein of unknown function (DUF4003)
LKCGKMCK_00664 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
LKCGKMCK_00665 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LKCGKMCK_00666 6.13e-199 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LKCGKMCK_00667 1.18e-227 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
LKCGKMCK_00668 6.74e-287 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
LKCGKMCK_00669 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
LKCGKMCK_00670 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
LKCGKMCK_00671 1.2e-283 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LKCGKMCK_00672 1.44e-165 yebC - - M - - - Membrane
LKCGKMCK_00674 2.66e-120 yebE - - S - - - UPF0316 protein
LKCGKMCK_00675 3.13e-38 yebG - - S - - - NETI protein
LKCGKMCK_00676 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LKCGKMCK_00677 9.39e-278 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LKCGKMCK_00678 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LKCGKMCK_00679 1.06e-170 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
LKCGKMCK_00680 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKCGKMCK_00681 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKCGKMCK_00682 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKCGKMCK_00683 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LKCGKMCK_00684 4.2e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
LKCGKMCK_00685 4.4e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LKCGKMCK_00686 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
LKCGKMCK_00687 2.07e-300 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LKCGKMCK_00688 5.26e-96 - - - K - - - helix_turn_helix ASNC type
LKCGKMCK_00689 1.91e-297 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
LKCGKMCK_00690 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
LKCGKMCK_00691 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
LKCGKMCK_00692 7.03e-246 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
LKCGKMCK_00693 7.62e-68 yerC - - S - - - protein conserved in bacteria
LKCGKMCK_00694 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
LKCGKMCK_00696 1.1e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LKCGKMCK_00697 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
LKCGKMCK_00698 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LKCGKMCK_00699 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
LKCGKMCK_00700 6.28e-253 yerI - - S - - - homoserine kinase type II (protein kinase fold)
LKCGKMCK_00701 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
LKCGKMCK_00702 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKCGKMCK_00703 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LKCGKMCK_00704 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LKCGKMCK_00705 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LKCGKMCK_00706 2.93e-201 yerO - - K - - - Transcriptional regulator
LKCGKMCK_00707 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LKCGKMCK_00708 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LKCGKMCK_00709 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LKCGKMCK_00710 3.63e-127 - - - L - - - Recombinase
LKCGKMCK_00711 5.61e-71 - - - L - - - Resolvase, N terminal domain
LKCGKMCK_00712 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
LKCGKMCK_00713 0.0 - - - L - - - DEAD-like helicases superfamily
LKCGKMCK_00714 1.13e-270 yeeC - - P - - - T5orf172
LKCGKMCK_00715 7.48e-05 - - - - - - - -
LKCGKMCK_00716 4.15e-42 - - - S - - - Colicin immunity protein / pyocin immunity protein
LKCGKMCK_00717 2.1e-109 - - - S - - - Protein of unknown function, DUF600
LKCGKMCK_00718 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
LKCGKMCK_00719 1.73e-246 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
LKCGKMCK_00720 1.33e-275 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
LKCGKMCK_00722 1.09e-162 yeeN - - K - - - transcriptional regulatory protein
LKCGKMCK_00724 1.86e-134 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_00725 4.95e-107 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
LKCGKMCK_00726 8.81e-206 yesF - - GM - - - NAD(P)H-binding
LKCGKMCK_00727 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
LKCGKMCK_00728 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
LKCGKMCK_00729 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
LKCGKMCK_00730 1.76e-132 yesJ - - K - - - Acetyltransferase (GNAT) family
LKCGKMCK_00732 3.52e-135 yesL - - S - - - Protein of unknown function, DUF624
LKCGKMCK_00733 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKCGKMCK_00734 5.07e-260 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
LKCGKMCK_00735 8.76e-316 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
LKCGKMCK_00736 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LKCGKMCK_00737 1.31e-212 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LKCGKMCK_00738 6.85e-255 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
LKCGKMCK_00739 0.0 yesS - - K - - - Transcriptional regulator
LKCGKMCK_00740 3.56e-171 - - - E - - - GDSL-like Lipase/Acylhydrolase
LKCGKMCK_00741 1.41e-169 yesU - - S - - - Domain of unknown function (DUF1961)
LKCGKMCK_00742 3.44e-146 - - - S - - - Protein of unknown function, DUF624
LKCGKMCK_00743 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
LKCGKMCK_00744 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
LKCGKMCK_00745 9.13e-160 - - - E - - - GDSL-like Lipase/Acylhydrolase
LKCGKMCK_00746 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
LKCGKMCK_00747 0.0 yetA - - - - - - -
LKCGKMCK_00748 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LKCGKMCK_00749 1.01e-227 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
LKCGKMCK_00750 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LKCGKMCK_00751 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
LKCGKMCK_00752 3.13e-158 yetF - - S - - - membrane
LKCGKMCK_00753 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
LKCGKMCK_00754 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKCGKMCK_00755 9.79e-45 - - - - - - - -
LKCGKMCK_00756 3.87e-114 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKCGKMCK_00757 1.97e-54 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKCGKMCK_00758 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
LKCGKMCK_00759 2.55e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
LKCGKMCK_00760 7.35e-203 - - - EG - - - EamA-like transporter family
LKCGKMCK_00761 6.74e-117 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKCGKMCK_00762 4.77e-270 yetM - - CH - - - FAD binding domain
LKCGKMCK_00763 6.1e-255 yetN - - S - - - Protein of unknown function (DUF3900)
LKCGKMCK_00764 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
LKCGKMCK_00765 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LKCGKMCK_00766 2.15e-190 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
LKCGKMCK_00767 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
LKCGKMCK_00768 9.79e-232 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
LKCGKMCK_00769 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
LKCGKMCK_00770 2.84e-244 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
LKCGKMCK_00771 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LKCGKMCK_00772 9.43e-171 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LKCGKMCK_00773 4.16e-313 yfnA - - E ko:K03294 - ko00000 amino acid
LKCGKMCK_00774 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LKCGKMCK_00775 5.14e-161 yfmS - - NT - - - chemotaxis protein
LKCGKMCK_00776 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LKCGKMCK_00777 6.48e-99 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
LKCGKMCK_00778 3.03e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
LKCGKMCK_00779 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
LKCGKMCK_00780 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LKCGKMCK_00781 1.86e-266 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
LKCGKMCK_00782 1.86e-107 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
LKCGKMCK_00783 4.21e-242 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
LKCGKMCK_00784 1.72e-268 - - - G - - - Major Facilitator Superfamily
LKCGKMCK_00785 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
LKCGKMCK_00786 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
LKCGKMCK_00787 2.1e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKCGKMCK_00788 2.85e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKCGKMCK_00789 2.88e-221 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
LKCGKMCK_00790 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
LKCGKMCK_00791 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
LKCGKMCK_00792 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
LKCGKMCK_00793 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LKCGKMCK_00794 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LKCGKMCK_00795 3.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LKCGKMCK_00796 1.45e-232 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
LKCGKMCK_00798 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LKCGKMCK_00799 7.21e-194 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LKCGKMCK_00800 1.43e-277 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LKCGKMCK_00801 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
LKCGKMCK_00802 2.51e-159 yflK - - S - - - protein conserved in bacteria
LKCGKMCK_00803 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
LKCGKMCK_00804 6.9e-27 yflI - - - - - - -
LKCGKMCK_00805 3.63e-66 yflH - - S - - - Protein of unknown function (DUF3243)
LKCGKMCK_00806 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
LKCGKMCK_00807 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LKCGKMCK_00808 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LKCGKMCK_00809 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
LKCGKMCK_00810 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
LKCGKMCK_00811 2.19e-249 yfkT - - E ko:K06309 - ko00000 Spore germination protein
LKCGKMCK_00813 2.28e-271 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
LKCGKMCK_00814 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
LKCGKMCK_00815 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKCGKMCK_00816 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
LKCGKMCK_00817 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
LKCGKMCK_00818 5.27e-161 frp - - C - - - nitroreductase
LKCGKMCK_00819 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LKCGKMCK_00820 8.44e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
LKCGKMCK_00821 6.21e-266 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LKCGKMCK_00822 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
LKCGKMCK_00823 2.14e-110 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LKCGKMCK_00824 2.53e-67 yfkI - - S - - - gas vesicle protein
LKCGKMCK_00825 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
LKCGKMCK_00826 1.64e-12 - - - - - - - -
LKCGKMCK_00827 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LKCGKMCK_00828 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
LKCGKMCK_00829 3.69e-189 yfkD - - S - - - YfkD-like protein
LKCGKMCK_00830 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
LKCGKMCK_00831 1.76e-283 yfkA - - S - - - YfkB-like domain
LKCGKMCK_00832 3.26e-36 yfjT - - - - - - -
LKCGKMCK_00833 7.24e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
LKCGKMCK_00834 4.82e-194 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LKCGKMCK_00835 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
LKCGKMCK_00836 1.94e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LKCGKMCK_00837 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LKCGKMCK_00838 3e-53 - - - S - - - YfzA-like protein
LKCGKMCK_00839 1.21e-243 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LKCGKMCK_00840 9.55e-111 yfjM - - S - - - Psort location Cytoplasmic, score
LKCGKMCK_00842 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LKCGKMCK_00843 2.75e-244 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LKCGKMCK_00844 4.19e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LKCGKMCK_00845 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LKCGKMCK_00846 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
LKCGKMCK_00847 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
LKCGKMCK_00848 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
LKCGKMCK_00849 1.53e-104 - - - S - - - Family of unknown function (DUF5381)
LKCGKMCK_00850 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
LKCGKMCK_00851 2.5e-185 yfjC - - - - - - -
LKCGKMCK_00852 1.94e-270 yfjB - - - - - - -
LKCGKMCK_00853 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
LKCGKMCK_00854 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LKCGKMCK_00855 7.45e-182 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
LKCGKMCK_00856 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKCGKMCK_00857 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
LKCGKMCK_00858 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LKCGKMCK_00859 2.01e-84 yfiD3 - - S - - - DoxX
LKCGKMCK_00860 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
LKCGKMCK_00861 1.28e-228 - - - K ko:K02099 - ko00000,ko03000 AraC-like ligand binding domain
LKCGKMCK_00862 0.0 yfiG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LKCGKMCK_00863 5.47e-234 - - - G - - - Xylose isomerase
LKCGKMCK_00864 5.17e-295 - - - S - - - Oxidoreductase
LKCGKMCK_00866 7.54e-276 baeS - - T - - - Histidine kinase
LKCGKMCK_00867 1.05e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
LKCGKMCK_00868 3.35e-218 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_00869 3.66e-274 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LKCGKMCK_00870 4.56e-267 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
LKCGKMCK_00871 1.89e-128 padR - - K - - - transcriptional
LKCGKMCK_00872 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
LKCGKMCK_00873 2.29e-253 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LKCGKMCK_00874 4.18e-141 yfiR - - K - - - Transcriptional regulator
LKCGKMCK_00875 4.51e-281 yfiS - - EGP - - - Major facilitator superfamily
LKCGKMCK_00876 2.41e-129 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
LKCGKMCK_00877 0.0 yfiU - - EGP - - - the major facilitator superfamily
LKCGKMCK_00878 5.39e-106 yfiV - - K - - - transcriptional
LKCGKMCK_00879 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LKCGKMCK_00880 2.81e-233 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LKCGKMCK_00881 1.54e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKCGKMCK_00882 5.18e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKCGKMCK_00883 7.61e-215 yfhB - - S - - - PhzF family
LKCGKMCK_00884 2.87e-138 yfhC - - C - - - nitroreductase
LKCGKMCK_00885 8.86e-35 yfhD - - S - - - YfhD-like protein
LKCGKMCK_00887 1.13e-221 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
LKCGKMCK_00888 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
LKCGKMCK_00889 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
LKCGKMCK_00891 2.45e-268 yfhI - - EGP - - - -transporter
LKCGKMCK_00892 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
LKCGKMCK_00893 8.95e-60 yfhJ - - S - - - WVELL protein
LKCGKMCK_00894 3.58e-119 yfhK - - T - - - Bacterial SH3 domain homologues
LKCGKMCK_00895 5.4e-67 yfhL - - S - - - SdpI/YhfL protein family
LKCGKMCK_00896 3.37e-219 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
LKCGKMCK_00897 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LKCGKMCK_00898 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
LKCGKMCK_00899 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
LKCGKMCK_00900 8.47e-268 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
LKCGKMCK_00901 1.73e-48 yfhS - - - - - - -
LKCGKMCK_00902 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKCGKMCK_00903 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
LKCGKMCK_00904 2.01e-49 ygaB - - S - - - YgaB-like protein
LKCGKMCK_00905 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
LKCGKMCK_00906 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
LKCGKMCK_00907 1.87e-238 ygaE - - S - - - Membrane
LKCGKMCK_00908 1.19e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
LKCGKMCK_00909 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
LKCGKMCK_00910 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
LKCGKMCK_00911 4.67e-75 ygzB - - S - - - UPF0295 protein
LKCGKMCK_00912 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
LKCGKMCK_00913 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LKCGKMCK_00930 2.22e-185 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
LKCGKMCK_00931 3.88e-37 - - - - - - - -
LKCGKMCK_00932 6.95e-173 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
LKCGKMCK_00933 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LKCGKMCK_00934 0.0 ygaK - - C - - - Berberine and berberine like
LKCGKMCK_00936 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LKCGKMCK_00937 4.15e-185 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LKCGKMCK_00938 1.78e-219 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
LKCGKMCK_00939 5.86e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LKCGKMCK_00940 9.35e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
LKCGKMCK_00942 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LKCGKMCK_00943 2.79e-102 ygaO - - - - - - -
LKCGKMCK_00944 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_00946 1.92e-147 yhzB - - S - - - B3/4 domain
LKCGKMCK_00947 5.09e-285 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LKCGKMCK_00948 4.79e-226 yhbB - - S - - - Putative amidase domain
LKCGKMCK_00949 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LKCGKMCK_00950 3.4e-143 yhbD - - K - - - Protein of unknown function (DUF4004)
LKCGKMCK_00951 2.29e-96 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
LKCGKMCK_00952 4.08e-110 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
LKCGKMCK_00953 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
LKCGKMCK_00954 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
LKCGKMCK_00955 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
LKCGKMCK_00956 3.8e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
LKCGKMCK_00957 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
LKCGKMCK_00958 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
LKCGKMCK_00959 3.95e-59 yhcC - - - - - - -
LKCGKMCK_00961 2.92e-69 - - - - - - - -
LKCGKMCK_00962 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_00963 3.38e-158 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_00964 6.47e-213 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_00965 3.45e-212 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LKCGKMCK_00966 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
LKCGKMCK_00967 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LKCGKMCK_00968 2.47e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
LKCGKMCK_00969 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKCGKMCK_00970 3.23e-80 yhcM - - - - - - -
LKCGKMCK_00971 2.69e-111 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LKCGKMCK_00972 3.96e-227 yhcP - - - - - - -
LKCGKMCK_00973 1.68e-146 yhcQ - - M - - - Spore coat protein
LKCGKMCK_00974 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LKCGKMCK_00975 3.9e-138 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
LKCGKMCK_00976 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LKCGKMCK_00977 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
LKCGKMCK_00978 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
LKCGKMCK_00979 3.04e-155 yhcW - - S ko:K07025 - ko00000 hydrolase
LKCGKMCK_00980 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LKCGKMCK_00981 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LKCGKMCK_00982 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LKCGKMCK_00983 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LKCGKMCK_00984 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LKCGKMCK_00985 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LKCGKMCK_00986 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
LKCGKMCK_00987 2.29e-273 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
LKCGKMCK_00988 5.68e-148 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKCGKMCK_00989 5.68e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
LKCGKMCK_00990 1.65e-51 yhdB - - S - - - YhdB-like protein
LKCGKMCK_00991 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
LKCGKMCK_00992 2.4e-275 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LKCGKMCK_00993 1.37e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
LKCGKMCK_00994 5.29e-307 ygxB - - M - - - Conserved TM helix
LKCGKMCK_00995 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
LKCGKMCK_00996 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
LKCGKMCK_00997 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LKCGKMCK_00998 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_00999 5.51e-263 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LKCGKMCK_01000 1.41e-208 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKCGKMCK_01001 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
LKCGKMCK_01002 4.29e-310 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LKCGKMCK_01003 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKCGKMCK_01004 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKCGKMCK_01005 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
LKCGKMCK_01006 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
LKCGKMCK_01007 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LKCGKMCK_01008 6.74e-244 yhdN - - C - - - Aldo keto reductase
LKCGKMCK_01009 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LKCGKMCK_01010 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LKCGKMCK_01011 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
LKCGKMCK_01012 4.37e-285 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LKCGKMCK_01013 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
LKCGKMCK_01014 2.69e-70 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LKCGKMCK_01015 1.01e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LKCGKMCK_01016 5.44e-174 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LKCGKMCK_01017 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
LKCGKMCK_01018 4.51e-260 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
LKCGKMCK_01019 2.93e-180 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LKCGKMCK_01020 5.7e-200 nodB1 - - G - - - deacetylase
LKCGKMCK_01021 2.23e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LKCGKMCK_01022 3.94e-307 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
LKCGKMCK_01023 3.85e-109 nhaX - - T - - - Belongs to the universal stress protein A family
LKCGKMCK_01024 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LKCGKMCK_01025 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LKCGKMCK_01026 3.31e-143 yheG - - GM - - - NAD(P)H-binding
LKCGKMCK_01027 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
LKCGKMCK_01028 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
LKCGKMCK_01029 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
LKCGKMCK_01030 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
LKCGKMCK_01031 1.51e-261 yheB - - S - - - Belongs to the UPF0754 family
LKCGKMCK_01032 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
LKCGKMCK_01033 6.69e-264 yhaZ - - L - - - DNA alkylation repair enzyme
LKCGKMCK_01034 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
LKCGKMCK_01035 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
LKCGKMCK_01036 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
LKCGKMCK_01037 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
LKCGKMCK_01039 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
LKCGKMCK_01040 2.29e-36 - - - S - - - YhzD-like protein
LKCGKMCK_01041 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_01042 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
LKCGKMCK_01043 9.85e-303 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
LKCGKMCK_01044 0.0 yhaN - - L - - - AAA domain
LKCGKMCK_01045 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
LKCGKMCK_01046 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
LKCGKMCK_01047 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LKCGKMCK_01048 1.4e-116 yhaK - - S - - - Putative zincin peptidase
LKCGKMCK_01049 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
LKCGKMCK_01050 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
LKCGKMCK_01051 1.74e-54 yhaH - - S - - - YtxH-like protein
LKCGKMCK_01052 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
LKCGKMCK_01053 1.84e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LKCGKMCK_01054 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LKCGKMCK_01055 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
LKCGKMCK_01056 3.11e-272 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LKCGKMCK_01057 5e-162 ecsC - - S - - - EcsC protein family
LKCGKMCK_01058 4.8e-295 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LKCGKMCK_01059 8.98e-317 yhfA - - C - - - membrane
LKCGKMCK_01060 1.33e-23 - - - C - - - Rubrerythrin
LKCGKMCK_01061 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
LKCGKMCK_01062 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LKCGKMCK_01063 7.78e-261 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LKCGKMCK_01064 2.06e-232 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
LKCGKMCK_01065 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LKCGKMCK_01066 3.49e-133 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_01067 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
LKCGKMCK_01068 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LKCGKMCK_01069 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
LKCGKMCK_01070 2.68e-253 yhfE - - G - - - peptidase M42
LKCGKMCK_01071 3.75e-94 - - - S - - - ASCH
LKCGKMCK_01072 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKCGKMCK_01073 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
LKCGKMCK_01074 1.21e-246 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
LKCGKMCK_01075 1.82e-144 yhfK - - GM - - - NmrA-like family
LKCGKMCK_01076 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
LKCGKMCK_01077 2.78e-85 yhfM - - - - - - -
LKCGKMCK_01078 9.64e-308 yhfN - - O - - - Peptidase M48
LKCGKMCK_01079 2.94e-261 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LKCGKMCK_01080 2.75e-105 - - - K - - - acetyltransferase
LKCGKMCK_01081 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
LKCGKMCK_01082 2.77e-223 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
LKCGKMCK_01083 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
LKCGKMCK_01084 1.19e-256 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LKCGKMCK_01085 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
LKCGKMCK_01086 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
LKCGKMCK_01087 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
LKCGKMCK_01088 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
LKCGKMCK_01089 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKCGKMCK_01090 9.84e-45 yhzC - - S - - - IDEAL
LKCGKMCK_01091 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
LKCGKMCK_01092 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LKCGKMCK_01093 5e-57 yhjA - - S - - - Excalibur calcium-binding domain
LKCGKMCK_01094 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKCGKMCK_01095 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
LKCGKMCK_01096 2.57e-78 yhjD - - - - - - -
LKCGKMCK_01097 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
LKCGKMCK_01098 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LKCGKMCK_01099 0.0 yhjG - - CH - - - FAD binding domain
LKCGKMCK_01100 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKCGKMCK_01101 3.12e-273 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
LKCGKMCK_01102 3.98e-257 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
LKCGKMCK_01103 2.63e-205 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
LKCGKMCK_01104 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
LKCGKMCK_01105 1.07e-239 yhjM - - K - - - Transcriptional regulator
LKCGKMCK_01106 2.14e-260 yhjN - - S ko:K07120 - ko00000 membrane
LKCGKMCK_01107 1.27e-272 - - - EGP - - - Transmembrane secretion effector
LKCGKMCK_01108 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
LKCGKMCK_01109 3.54e-77 yhjQ - - C - - - COG1145 Ferredoxin
LKCGKMCK_01110 9.3e-102 yhjR - - S - - - Rubrerythrin
LKCGKMCK_01111 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
LKCGKMCK_01112 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
LKCGKMCK_01113 1.2e-281 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LKCGKMCK_01114 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
LKCGKMCK_01115 1.34e-66 yisB - - V - - - COG1403 Restriction endonuclease
LKCGKMCK_01116 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
LKCGKMCK_01117 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
LKCGKMCK_01118 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
LKCGKMCK_01119 8.23e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
LKCGKMCK_01120 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
LKCGKMCK_01121 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
LKCGKMCK_01122 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
LKCGKMCK_01123 3.96e-224 cotH - - M ko:K06330 - ko00000 Spore Coat
LKCGKMCK_01124 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LKCGKMCK_01125 1.02e-74 yisL - - S - - - UPF0344 protein
LKCGKMCK_01126 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LKCGKMCK_01127 7.48e-137 yisN - - S - - - Protein of unknown function (DUF2777)
LKCGKMCK_01128 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LKCGKMCK_01129 1.85e-115 yizA - - S - - - Damage-inducible protein DinB
LKCGKMCK_01130 6.82e-193 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
LKCGKMCK_01131 1.01e-310 yisQ - - V - - - Mate efflux family protein
LKCGKMCK_01132 1.41e-207 yisR - - K - - - Transcriptional regulator
LKCGKMCK_01133 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
LKCGKMCK_01134 9.72e-254 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
LKCGKMCK_01135 7.28e-122 yisT - - S - - - DinB family
LKCGKMCK_01136 5.42e-140 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
LKCGKMCK_01137 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKCGKMCK_01138 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
LKCGKMCK_01139 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LKCGKMCK_01140 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
LKCGKMCK_01141 1.37e-295 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
LKCGKMCK_01142 9.51e-185 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
LKCGKMCK_01143 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
LKCGKMCK_01144 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
LKCGKMCK_01145 6.62e-140 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LKCGKMCK_01146 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LKCGKMCK_01147 1.01e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LKCGKMCK_01148 7.86e-207 yitH - - K - - - Acetyltransferase (GNAT) domain
LKCGKMCK_01149 3.34e-106 - - - S - - - Acetyltransferase (GNAT) domain
LKCGKMCK_01150 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LKCGKMCK_01151 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
LKCGKMCK_01152 1.94e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
LKCGKMCK_01153 4.16e-122 - - - - - - - -
LKCGKMCK_01154 1.42e-218 - - - - - - - -
LKCGKMCK_01155 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
LKCGKMCK_01156 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
LKCGKMCK_01157 7.76e-123 - - - - - - - -
LKCGKMCK_01158 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
LKCGKMCK_01159 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
LKCGKMCK_01160 9.13e-202 yitS - - S - - - protein conserved in bacteria
LKCGKMCK_01161 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LKCGKMCK_01162 1.61e-92 ipi - - S - - - Intracellular proteinase inhibitor
LKCGKMCK_01163 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
LKCGKMCK_01164 3.19e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LKCGKMCK_01165 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LKCGKMCK_01166 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
LKCGKMCK_01167 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
LKCGKMCK_01168 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
LKCGKMCK_01169 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
LKCGKMCK_01170 9.02e-256 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LKCGKMCK_01171 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LKCGKMCK_01172 5.4e-177 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
LKCGKMCK_01173 1.69e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
LKCGKMCK_01174 1.4e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LKCGKMCK_01175 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
LKCGKMCK_01176 3.66e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LKCGKMCK_01177 2.51e-39 yjzC - - S - - - YjzC-like protein
LKCGKMCK_01178 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
LKCGKMCK_01179 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
LKCGKMCK_01180 5.41e-134 yjaV - - - - - - -
LKCGKMCK_01181 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
LKCGKMCK_01182 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
LKCGKMCK_01183 2.67e-38 yjzB - - - - - - -
LKCGKMCK_01184 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LKCGKMCK_01185 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LKCGKMCK_01186 9.48e-193 yjaZ - - O - - - Zn-dependent protease
LKCGKMCK_01187 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKCGKMCK_01188 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKCGKMCK_01189 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
LKCGKMCK_01190 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKCGKMCK_01191 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKCGKMCK_01192 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
LKCGKMCK_01193 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
LKCGKMCK_01194 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LKCGKMCK_01195 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKCGKMCK_01196 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKCGKMCK_01197 1.37e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKCGKMCK_01198 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKCGKMCK_01199 3.98e-248 yjbB - - EGP - - - Major Facilitator Superfamily
LKCGKMCK_01200 2.65e-133 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKCGKMCK_01201 3.51e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LKCGKMCK_01202 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
LKCGKMCK_01203 6.89e-151 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LKCGKMCK_01204 1.31e-283 coiA - - S ko:K06198 - ko00000 Competence protein
LKCGKMCK_01205 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
LKCGKMCK_01206 2.68e-28 - - - - - - - -
LKCGKMCK_01208 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
LKCGKMCK_01209 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
LKCGKMCK_01210 3.42e-127 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LKCGKMCK_01211 5.15e-130 yjbK - - S - - - protein conserved in bacteria
LKCGKMCK_01212 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
LKCGKMCK_01213 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
LKCGKMCK_01214 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LKCGKMCK_01215 9.4e-206 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LKCGKMCK_01216 8.09e-181 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
LKCGKMCK_01217 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LKCGKMCK_01218 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LKCGKMCK_01219 4.01e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
LKCGKMCK_01220 1.14e-277 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
LKCGKMCK_01221 5.35e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
LKCGKMCK_01222 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LKCGKMCK_01223 1.52e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LKCGKMCK_01224 8.38e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LKCGKMCK_01225 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
LKCGKMCK_01226 2.32e-107 yjbX - - S - - - Spore coat protein
LKCGKMCK_01227 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
LKCGKMCK_01228 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
LKCGKMCK_01229 3.55e-110 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
LKCGKMCK_01230 1.08e-54 cotW - - - ko:K06341 - ko00000 -
LKCGKMCK_01231 1.44e-72 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
LKCGKMCK_01232 3.03e-76 yjcA - - S - - - Protein of unknown function (DUF1360)
LKCGKMCK_01235 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
LKCGKMCK_01236 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LKCGKMCK_01237 6.31e-51 - - - - - - - -
LKCGKMCK_01238 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKCGKMCK_01239 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
LKCGKMCK_01240 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
LKCGKMCK_01241 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LKCGKMCK_01242 6.4e-281 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LKCGKMCK_01243 2.13e-129 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
LKCGKMCK_01244 2.58e-274 yjcL - - S - - - Protein of unknown function (DUF819)
LKCGKMCK_01247 3.75e-269 - - - S - - - Putative amidase domain
LKCGKMCK_01248 1.52e-68 yjcN - - - - - - -
LKCGKMCK_01251 2.24e-106 - - - L - - - Transposase
LKCGKMCK_01252 5.68e-100 yjcP - - - - - - -
LKCGKMCK_01253 1.01e-65 - - - S - - - YjcQ protein
LKCGKMCK_01254 3.29e-121 yqaS - - L - - - DNA packaging
LKCGKMCK_01255 3.8e-63 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
LKCGKMCK_01256 3.42e-181 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LKCGKMCK_01257 0.000759 - - - - - - - -
LKCGKMCK_01258 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
LKCGKMCK_01259 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKCGKMCK_01260 6.2e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LKCGKMCK_01261 4.79e-78 yjdF3 - - S - - - Protein of unknown function (DUF2992)
LKCGKMCK_01262 1.36e-121 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LKCGKMCK_01264 1.01e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LKCGKMCK_01265 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
LKCGKMCK_01266 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
LKCGKMCK_01267 5.31e-224 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LKCGKMCK_01269 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
LKCGKMCK_01270 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
LKCGKMCK_01271 1.95e-30 yjfB - - S - - - Putative motility protein
LKCGKMCK_01272 3.24e-219 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
LKCGKMCK_01273 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
LKCGKMCK_01274 1.22e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
LKCGKMCK_01275 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
LKCGKMCK_01276 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
LKCGKMCK_01278 1.91e-149 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
LKCGKMCK_01280 1.48e-289 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LKCGKMCK_01281 8.74e-280 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LKCGKMCK_01282 1.11e-41 - - - - - - - -
LKCGKMCK_01283 8.69e-189 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
LKCGKMCK_01284 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
LKCGKMCK_01285 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LKCGKMCK_01286 1.09e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
LKCGKMCK_01287 8.91e-121 yjlB - - S - - - Cupin domain
LKCGKMCK_01288 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
LKCGKMCK_01289 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LKCGKMCK_01290 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
LKCGKMCK_01291 6.34e-316 - - - G ko:K03292 - ko00000 symporter YjmB
LKCGKMCK_01292 2.02e-248 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
LKCGKMCK_01293 1.6e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
LKCGKMCK_01294 1.66e-274 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
LKCGKMCK_01295 1.34e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LKCGKMCK_01296 1.37e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
LKCGKMCK_01297 6.95e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
LKCGKMCK_01298 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
LKCGKMCK_01299 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
LKCGKMCK_01300 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
LKCGKMCK_01301 4.87e-106 yjoA - - S - - - DinB family
LKCGKMCK_01302 6.08e-314 VCP - - O - - - AAA domain (dynein-related subfamily)
LKCGKMCK_01303 1.6e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LKCGKMCK_01305 1.79e-55 - - - S - - - YCII-related domain
LKCGKMCK_01306 1.37e-220 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LKCGKMCK_01307 3.31e-81 yjqA - - S - - - Bacterial PH domain
LKCGKMCK_01308 1.47e-143 yjqB - - S - - - Pfam:DUF867
LKCGKMCK_01309 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
LKCGKMCK_01310 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
LKCGKMCK_01311 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
LKCGKMCK_01313 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
LKCGKMCK_01314 7.48e-153 xkdC - - L - - - Bacterial dnaA protein
LKCGKMCK_01318 5.95e-112 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LKCGKMCK_01319 1.18e-179 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
LKCGKMCK_01320 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
LKCGKMCK_01321 0.0 yqbA - - S - - - portal protein
LKCGKMCK_01322 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
LKCGKMCK_01323 3.91e-217 xkdG - - S - - - Phage capsid family
LKCGKMCK_01324 2.06e-85 yqbG - - S - - - Protein of unknown function (DUF3199)
LKCGKMCK_01325 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
LKCGKMCK_01326 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
LKCGKMCK_01327 2.87e-101 xkdJ - - - - - - -
LKCGKMCK_01328 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
LKCGKMCK_01329 6.01e-99 xkdM - - S - - - Phage tail tube protein
LKCGKMCK_01330 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
LKCGKMCK_01331 0.0 xkdO - - L - - - Transglycosylase SLT domain
LKCGKMCK_01332 1.77e-158 xkdP - - S - - - Lysin motif
LKCGKMCK_01333 2.31e-232 xkdQ - - G - - - NLP P60 protein
LKCGKMCK_01334 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
LKCGKMCK_01335 1.97e-92 xkdS - - S - - - Protein of unknown function (DUF2634)
LKCGKMCK_01336 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LKCGKMCK_01337 9.63e-136 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
LKCGKMCK_01338 4.43e-56 - - - - - - - -
LKCGKMCK_01339 0.0 - - - - - - - -
LKCGKMCK_01340 8.68e-74 xkdW - - S - - - XkdW protein
LKCGKMCK_01341 9.34e-33 xkdX - - - - - - -
LKCGKMCK_01342 1.51e-198 xepA - - - - - - -
LKCGKMCK_01343 7.71e-52 xhlA - - S - - - Haemolysin XhlA
LKCGKMCK_01344 8.12e-53 xhlB - - S - - - SPP1 phage holin
LKCGKMCK_01345 5.76e-212 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
LKCGKMCK_01346 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
LKCGKMCK_01347 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
LKCGKMCK_01348 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
LKCGKMCK_01349 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
LKCGKMCK_01350 7.7e-311 steT - - E ko:K03294 - ko00000 amino acid
LKCGKMCK_01351 3.43e-234 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LKCGKMCK_01353 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LKCGKMCK_01354 1.34e-230 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LKCGKMCK_01356 6.72e-288 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKCGKMCK_01357 1.54e-183 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
LKCGKMCK_01358 2.42e-197 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
LKCGKMCK_01359 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKCGKMCK_01360 6.35e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKCGKMCK_01361 6.22e-242 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKCGKMCK_01362 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LKCGKMCK_01364 4.26e-228 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
LKCGKMCK_01365 1.24e-259 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LKCGKMCK_01366 2.56e-219 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LKCGKMCK_01367 1.77e-238 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKCGKMCK_01368 9.83e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
LKCGKMCK_01369 4.37e-206 ykgA - - E - - - Amidinotransferase
LKCGKMCK_01370 3.82e-120 ykhA - - I - - - Acyl-CoA hydrolase
LKCGKMCK_01371 2.65e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LKCGKMCK_01372 5.85e-13 - - - - - - - -
LKCGKMCK_01373 4.81e-168 ykjA - - S - - - Protein of unknown function (DUF421)
LKCGKMCK_01374 1.57e-128 ykkA - - S - - - Protein of unknown function (DUF664)
LKCGKMCK_01375 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LKCGKMCK_01376 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
LKCGKMCK_01377 2.86e-68 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
LKCGKMCK_01378 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LKCGKMCK_01379 3.16e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LKCGKMCK_01380 3.38e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LKCGKMCK_01381 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
LKCGKMCK_01382 1.21e-98 ohrR - - K - - - COG1846 Transcriptional regulators
LKCGKMCK_01383 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
LKCGKMCK_01385 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
LKCGKMCK_01386 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LKCGKMCK_01387 3.66e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LKCGKMCK_01388 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKCGKMCK_01389 3.8e-175 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
LKCGKMCK_01390 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_01391 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
LKCGKMCK_01392 7.28e-144 ykoF - - S - - - YKOF-related Family
LKCGKMCK_01393 1.28e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKCGKMCK_01394 8.05e-312 ykoH - - T - - - Histidine kinase
LKCGKMCK_01395 3.35e-146 ykoI - - S - - - Peptidase propeptide and YPEB domain
LKCGKMCK_01396 2.24e-112 ykoJ - - S - - - Peptidase propeptide and YPEB domain
LKCGKMCK_01397 1.45e-08 - - - - - - - -
LKCGKMCK_01399 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
LKCGKMCK_01400 1.49e-70 tnrA - - K - - - transcriptional
LKCGKMCK_01401 1.63e-25 - - - - - - - -
LKCGKMCK_01402 3.04e-36 ykoL - - - - - - -
LKCGKMCK_01403 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
LKCGKMCK_01404 1.19e-281 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
LKCGKMCK_01405 2.48e-129 ykoP - - G - - - polysaccharide deacetylase
LKCGKMCK_01406 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
LKCGKMCK_01407 0.0 ykoS - - - - - - -
LKCGKMCK_01408 5.72e-239 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
LKCGKMCK_01409 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
LKCGKMCK_01410 7.55e-206 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LKCGKMCK_01411 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
LKCGKMCK_01412 4.48e-153 ykoX - - S - - - membrane-associated protein
LKCGKMCK_01413 1.88e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LKCGKMCK_01414 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKCGKMCK_01415 9.33e-219 rsgI - - S - - - Anti-sigma factor N-terminus
LKCGKMCK_01416 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
LKCGKMCK_01417 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
LKCGKMCK_01418 3.4e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
LKCGKMCK_01419 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
LKCGKMCK_01421 8.33e-31 ykzE - - - - - - -
LKCGKMCK_01422 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
LKCGKMCK_01423 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKCGKMCK_01424 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LKCGKMCK_01426 1.62e-253 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LKCGKMCK_01427 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LKCGKMCK_01428 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LKCGKMCK_01429 4.81e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LKCGKMCK_01430 3.39e-295 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
LKCGKMCK_01431 1.07e-176 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LKCGKMCK_01432 4.52e-147 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
LKCGKMCK_01433 1.5e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LKCGKMCK_01434 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
LKCGKMCK_01436 5.84e-95 eag - - - - - - -
LKCGKMCK_01437 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LKCGKMCK_01438 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
LKCGKMCK_01439 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
LKCGKMCK_01440 3.23e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
LKCGKMCK_01441 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
LKCGKMCK_01442 4.26e-230 ykvI - - S - - - membrane
LKCGKMCK_01443 1.11e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LKCGKMCK_01444 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
LKCGKMCK_01445 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LKCGKMCK_01446 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LKCGKMCK_01447 2.8e-81 ykvN - - K - - - Transcriptional regulator
LKCGKMCK_01448 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LKCGKMCK_01449 2.69e-275 - - - M - - - Glycosyl transferases group 1
LKCGKMCK_01450 1.85e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
LKCGKMCK_01451 2.5e-169 - - - G - - - Glycosyl hydrolases family 18
LKCGKMCK_01452 2.67e-62 ykvR - - S - - - Protein of unknown function (DUF3219)
LKCGKMCK_01453 5.43e-35 ykvS - - S - - - protein conserved in bacteria
LKCGKMCK_01454 2.6e-39 - - - - - - - -
LKCGKMCK_01455 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
LKCGKMCK_01456 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKCGKMCK_01457 5.79e-117 stoA - - CO - - - thiol-disulfide
LKCGKMCK_01458 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
LKCGKMCK_01459 3.99e-09 - - - - - - - -
LKCGKMCK_01460 7.85e-266 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
LKCGKMCK_01462 3.28e-230 ykvZ - - K - - - Transcriptional regulator
LKCGKMCK_01464 3.41e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
LKCGKMCK_01465 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKCGKMCK_01466 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
LKCGKMCK_01467 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LKCGKMCK_01468 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_01469 2.13e-257 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
LKCGKMCK_01470 5.49e-170 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKCGKMCK_01471 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LKCGKMCK_01472 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LKCGKMCK_01473 5.36e-172 ykwD - - J - - - protein with SCP PR1 domains
LKCGKMCK_01474 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LKCGKMCK_01475 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKCGKMCK_01476 5.32e-286 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LKCGKMCK_01477 1.05e-22 - - - - - - - -
LKCGKMCK_01478 4.24e-217 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
LKCGKMCK_01479 3.71e-110 ykyB - - S - - - YkyB-like protein
LKCGKMCK_01480 8.89e-306 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LKCGKMCK_01481 7.1e-116 ykuD - - S - - - protein conserved in bacteria
LKCGKMCK_01482 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
LKCGKMCK_01483 1.83e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKCGKMCK_01484 0.0 ybfG - - M - - - Putative peptidoglycan binding domain
LKCGKMCK_01485 1.52e-120 - - - M - - - Peptidoglycan-binding domain 1 protein
LKCGKMCK_01487 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
LKCGKMCK_01488 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
LKCGKMCK_01489 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
LKCGKMCK_01490 7.83e-38 ykzF - - S - - - Antirepressor AbbA
LKCGKMCK_01491 5.15e-100 ykuL - - S - - - CBS domain
LKCGKMCK_01492 6.52e-216 ccpC - - K - - - Transcriptional regulator
LKCGKMCK_01493 7.72e-114 - - - C ko:K03839 - ko00000 Flavodoxin domain
LKCGKMCK_01494 1.33e-226 ykuO - - - - - - -
LKCGKMCK_01495 1.3e-104 fld - - C ko:K03839 - ko00000 Flavodoxin
LKCGKMCK_01496 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LKCGKMCK_01497 7.99e-276 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LKCGKMCK_01498 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
LKCGKMCK_01499 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
LKCGKMCK_01500 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
LKCGKMCK_01501 6.25e-106 ykuV - - CO - - - thiol-disulfide
LKCGKMCK_01502 4.71e-122 rok - - K - - - Repressor of ComK
LKCGKMCK_01503 1.47e-201 yknT - - - ko:K06437 - ko00000 -
LKCGKMCK_01504 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LKCGKMCK_01505 6.5e-246 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LKCGKMCK_01506 1.05e-313 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
LKCGKMCK_01507 3.44e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
LKCGKMCK_01508 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
LKCGKMCK_01509 6.92e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LKCGKMCK_01510 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LKCGKMCK_01511 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LKCGKMCK_01512 1.6e-151 yknW - - S - - - Yip1 domain
LKCGKMCK_01513 4.93e-235 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LKCGKMCK_01514 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_01515 2.1e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LKCGKMCK_01516 1.49e-175 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_01517 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
LKCGKMCK_01518 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LKCGKMCK_01519 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LKCGKMCK_01520 5.43e-52 ykoA - - - - - - -
LKCGKMCK_01521 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LKCGKMCK_01522 2.99e-217 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LKCGKMCK_01523 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
LKCGKMCK_01524 1.09e-18 - - - S - - - Uncharacterized protein YkpC
LKCGKMCK_01525 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
LKCGKMCK_01526 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
LKCGKMCK_01527 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LKCGKMCK_01528 9.21e-208 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
LKCGKMCK_01529 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
LKCGKMCK_01530 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LKCGKMCK_01531 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LKCGKMCK_01532 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
LKCGKMCK_01533 2.03e-187 ykrA - - S - - - hydrolases of the HAD superfamily
LKCGKMCK_01534 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LKCGKMCK_01535 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LKCGKMCK_01536 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
LKCGKMCK_01537 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LKCGKMCK_01538 1.75e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LKCGKMCK_01539 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LKCGKMCK_01540 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LKCGKMCK_01541 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
LKCGKMCK_01542 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
LKCGKMCK_01543 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
LKCGKMCK_01544 1.3e-152 yktB - - S - - - Belongs to the UPF0637 family
LKCGKMCK_01545 4.48e-35 ykzI - - - - - - -
LKCGKMCK_01546 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
LKCGKMCK_01547 1.48e-100 ykzC - - S - - - Acetyltransferase (GNAT) family
LKCGKMCK_01548 1.28e-223 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LKCGKMCK_01549 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
LKCGKMCK_01550 0.0 ylaA - - - - - - -
LKCGKMCK_01551 1.44e-56 ylaB - - - - - - -
LKCGKMCK_01552 4.51e-118 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LKCGKMCK_01554 1.74e-57 ylaE - - - - - - -
LKCGKMCK_01555 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
LKCGKMCK_01556 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
LKCGKMCK_01557 4.4e-63 ylaH - - S - - - YlaH-like protein
LKCGKMCK_01558 8.92e-44 ylaI - - S - - - protein conserved in bacteria
LKCGKMCK_01559 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LKCGKMCK_01560 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
LKCGKMCK_01561 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LKCGKMCK_01562 4.25e-220 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
LKCGKMCK_01563 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
LKCGKMCK_01564 2.57e-273 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LKCGKMCK_01565 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LKCGKMCK_01566 2.97e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LKCGKMCK_01567 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LKCGKMCK_01568 5.85e-253 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LKCGKMCK_01569 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LKCGKMCK_01570 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LKCGKMCK_01571 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LKCGKMCK_01572 1.04e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
LKCGKMCK_01573 1.61e-81 ylbA - - S - - - YugN-like family
LKCGKMCK_01574 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
LKCGKMCK_01575 4.58e-258 ylbC - - S - - - protein with SCP PR1 domains
LKCGKMCK_01576 3.24e-89 ylbD - - S - - - Putative coat protein
LKCGKMCK_01577 1.73e-48 ylbE - - S - - - YlbE-like protein
LKCGKMCK_01578 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
LKCGKMCK_01579 4.36e-52 ylbG - - S - - - UPF0298 protein
LKCGKMCK_01580 2.12e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
LKCGKMCK_01581 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LKCGKMCK_01582 2.73e-282 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
LKCGKMCK_01583 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
LKCGKMCK_01584 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
LKCGKMCK_01585 5.94e-301 ylbM - - S - - - Belongs to the UPF0348 family
LKCGKMCK_01587 1.7e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
LKCGKMCK_01588 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
LKCGKMCK_01589 5.75e-108 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LKCGKMCK_01590 3.26e-116 ylbP - - K - - - n-acetyltransferase
LKCGKMCK_01591 1.66e-216 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LKCGKMCK_01592 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LKCGKMCK_01593 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
LKCGKMCK_01594 4.97e-220 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LKCGKMCK_01595 3.42e-68 ftsL - - D - - - Essential cell division protein
LKCGKMCK_01596 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LKCGKMCK_01597 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
LKCGKMCK_01598 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LKCGKMCK_01599 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LKCGKMCK_01600 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LKCGKMCK_01601 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LKCGKMCK_01602 9.42e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LKCGKMCK_01603 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
LKCGKMCK_01604 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LKCGKMCK_01605 3.45e-146 ylxW - - S - - - protein conserved in bacteria
LKCGKMCK_01606 1.06e-132 ylxX - - S - - - protein conserved in bacteria
LKCGKMCK_01607 5.37e-76 sbp - - S - - - small basic protein
LKCGKMCK_01608 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LKCGKMCK_01609 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LKCGKMCK_01610 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
LKCGKMCK_01611 1.06e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LKCGKMCK_01612 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKCGKMCK_01613 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKCGKMCK_01614 3.84e-189 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LKCGKMCK_01615 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
LKCGKMCK_01616 3.58e-51 ylmC - - S - - - sporulation protein
LKCGKMCK_01617 5.53e-205 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
LKCGKMCK_01618 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LKCGKMCK_01619 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LKCGKMCK_01620 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
LKCGKMCK_01621 3.67e-179 ylmH - - S - - - conserved protein, contains S4-like domain
LKCGKMCK_01622 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
LKCGKMCK_01623 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LKCGKMCK_01624 1.58e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
LKCGKMCK_01625 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LKCGKMCK_01626 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LKCGKMCK_01627 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LKCGKMCK_01628 2.24e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
LKCGKMCK_01629 4.4e-215 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
LKCGKMCK_01630 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LKCGKMCK_01631 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LKCGKMCK_01632 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
LKCGKMCK_01633 3.84e-185 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LKCGKMCK_01634 1.33e-224 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LKCGKMCK_01635 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LKCGKMCK_01636 3.8e-150 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LKCGKMCK_01638 3.58e-183 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
LKCGKMCK_01639 7.32e-230 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
LKCGKMCK_01640 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
LKCGKMCK_01641 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
LKCGKMCK_01642 1.24e-186 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
LKCGKMCK_01643 4.33e-189 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
LKCGKMCK_01644 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
LKCGKMCK_01645 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
LKCGKMCK_01646 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
LKCGKMCK_01647 8.41e-202 yloC - - S - - - stress-induced protein
LKCGKMCK_01648 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
LKCGKMCK_01649 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LKCGKMCK_01650 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LKCGKMCK_01651 4.59e-289 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LKCGKMCK_01652 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LKCGKMCK_01653 2.89e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LKCGKMCK_01654 2.21e-226 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LKCGKMCK_01655 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LKCGKMCK_01656 3.73e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LKCGKMCK_01657 3.03e-181 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
LKCGKMCK_01658 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
LKCGKMCK_01659 1.37e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LKCGKMCK_01660 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LKCGKMCK_01661 2.83e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
LKCGKMCK_01662 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
LKCGKMCK_01663 3.65e-78 yloU - - S - - - protein conserved in bacteria
LKCGKMCK_01664 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
LKCGKMCK_01665 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
LKCGKMCK_01666 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
LKCGKMCK_01667 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LKCGKMCK_01668 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LKCGKMCK_01669 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LKCGKMCK_01670 1.31e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LKCGKMCK_01671 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LKCGKMCK_01672 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LKCGKMCK_01673 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LKCGKMCK_01674 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
LKCGKMCK_01675 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LKCGKMCK_01676 1.67e-114 - - - - - - - -
LKCGKMCK_01677 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LKCGKMCK_01678 9.7e-309 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LKCGKMCK_01679 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
LKCGKMCK_01680 2.95e-50 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
LKCGKMCK_01681 5.89e-81 ylqD - - S - - - YlqD protein
LKCGKMCK_01682 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LKCGKMCK_01683 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
LKCGKMCK_01684 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LKCGKMCK_01685 1.2e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LKCGKMCK_01686 2.04e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LKCGKMCK_01687 0.0 ylqG - - - - - - -
LKCGKMCK_01688 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
LKCGKMCK_01689 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LKCGKMCK_01690 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LKCGKMCK_01691 6.53e-218 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
LKCGKMCK_01692 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LKCGKMCK_01693 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LKCGKMCK_01694 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
LKCGKMCK_01695 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LKCGKMCK_01696 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LKCGKMCK_01697 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LKCGKMCK_01698 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LKCGKMCK_01699 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
LKCGKMCK_01700 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
LKCGKMCK_01701 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
LKCGKMCK_01702 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LKCGKMCK_01703 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
LKCGKMCK_01704 2.11e-308 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LKCGKMCK_01705 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
LKCGKMCK_01706 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
LKCGKMCK_01707 2.31e-314 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
LKCGKMCK_01708 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
LKCGKMCK_01709 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
LKCGKMCK_01710 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
LKCGKMCK_01711 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LKCGKMCK_01712 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LKCGKMCK_01713 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
LKCGKMCK_01714 5.54e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
LKCGKMCK_01715 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
LKCGKMCK_01716 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
LKCGKMCK_01717 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
LKCGKMCK_01718 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LKCGKMCK_01719 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LKCGKMCK_01720 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
LKCGKMCK_01721 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
LKCGKMCK_01722 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LKCGKMCK_01723 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
LKCGKMCK_01724 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
LKCGKMCK_01725 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LKCGKMCK_01726 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LKCGKMCK_01727 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKCGKMCK_01728 6.91e-101 ylxL - - - - - - -
LKCGKMCK_01729 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
LKCGKMCK_01730 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LKCGKMCK_01731 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
LKCGKMCK_01732 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LKCGKMCK_01733 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LKCGKMCK_01734 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
LKCGKMCK_01735 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LKCGKMCK_01736 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
LKCGKMCK_01737 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LKCGKMCK_01738 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LKCGKMCK_01739 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
LKCGKMCK_01740 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
LKCGKMCK_01741 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
LKCGKMCK_01742 6.16e-63 ylxQ - - J - - - ribosomal protein
LKCGKMCK_01743 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LKCGKMCK_01744 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
LKCGKMCK_01745 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LKCGKMCK_01746 5.18e-221 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LKCGKMCK_01747 1.63e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LKCGKMCK_01748 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LKCGKMCK_01749 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LKCGKMCK_01750 1.29e-235 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
LKCGKMCK_01751 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
LKCGKMCK_01752 1.53e-56 ymxH - - S - - - YlmC YmxH family
LKCGKMCK_01753 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
LKCGKMCK_01754 9.94e-142 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LKCGKMCK_01755 1.66e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LKCGKMCK_01756 1.2e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LKCGKMCK_01757 1.57e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LKCGKMCK_01758 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LKCGKMCK_01759 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
LKCGKMCK_01760 4.94e-44 - - - S - - - YlzJ-like protein
LKCGKMCK_01761 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LKCGKMCK_01762 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_01763 2.08e-267 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LKCGKMCK_01764 3.45e-301 albE - - S - - - Peptidase M16
LKCGKMCK_01765 2.37e-309 ymfH - - S - - - zinc protease
LKCGKMCK_01766 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
LKCGKMCK_01767 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
LKCGKMCK_01768 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
LKCGKMCK_01769 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
LKCGKMCK_01770 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LKCGKMCK_01771 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
LKCGKMCK_01772 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LKCGKMCK_01773 8.43e-282 pbpX - - V - - - Beta-lactamase
LKCGKMCK_01774 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
LKCGKMCK_01775 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
LKCGKMCK_01776 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
LKCGKMCK_01777 3.02e-255 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
LKCGKMCK_01778 1.02e-278 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LKCGKMCK_01779 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LKCGKMCK_01780 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
LKCGKMCK_01781 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
LKCGKMCK_01782 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LKCGKMCK_01783 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LKCGKMCK_01784 7.19e-93 - - - S - - - Regulatory protein YrvL
LKCGKMCK_01786 1.38e-127 ymcC - - S - - - Membrane
LKCGKMCK_01787 2.94e-141 pksA - - K - - - Transcriptional regulator
LKCGKMCK_01788 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
LKCGKMCK_01789 1.31e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LKCGKMCK_01791 2.08e-239 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
LKCGKMCK_01792 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LKCGKMCK_01793 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
LKCGKMCK_01794 5.31e-304 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LKCGKMCK_01795 9.7e-314 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
LKCGKMCK_01796 2.48e-184 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
LKCGKMCK_01797 2.69e-177 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
LKCGKMCK_01798 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
LKCGKMCK_01799 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LKCGKMCK_01800 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
LKCGKMCK_01801 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
LKCGKMCK_01802 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
LKCGKMCK_01803 2.49e-297 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LKCGKMCK_01804 2.8e-81 ymzB - - - - - - -
LKCGKMCK_01805 4.8e-210 - - - S - - - Metallo-beta-lactamase superfamily
LKCGKMCK_01806 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
LKCGKMCK_01807 3.96e-163 ymaC - - S - - - Replication protein
LKCGKMCK_01808 1.03e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
LKCGKMCK_01809 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
LKCGKMCK_01810 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LKCGKMCK_01812 5.41e-76 ymaF - - S - - - YmaF family
LKCGKMCK_01813 9.69e-224 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LKCGKMCK_01814 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LKCGKMCK_01815 8.07e-32 - - - - - - - -
LKCGKMCK_01816 1.2e-30 ymzA - - - - - - -
LKCGKMCK_01817 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
LKCGKMCK_01818 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LKCGKMCK_01819 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LKCGKMCK_01820 2.24e-141 - - - - - - - -
LKCGKMCK_01821 1.72e-151 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LKCGKMCK_01822 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
LKCGKMCK_01823 4.47e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LKCGKMCK_01824 5.82e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LKCGKMCK_01825 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
LKCGKMCK_01826 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
LKCGKMCK_01827 2.23e-170 int - - L - - - Belongs to the 'phage' integrase family
LKCGKMCK_01828 6.02e-55 - - - E - - - Zn peptidase
LKCGKMCK_01829 1.14e-33 - - - K - - - Helix-turn-helix XRE-family like proteins
LKCGKMCK_01831 1.48e-31 - - - - - - - -
LKCGKMCK_01833 9.02e-105 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
LKCGKMCK_01836 2.28e-108 - - - L - - - DnaD domain protein
LKCGKMCK_01837 1.96e-17 - - - S - - - Loader and inhibitor of phage G40P
LKCGKMCK_01838 1.63e-212 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 replicative DNA helicase
LKCGKMCK_01839 5.34e-31 - - - - - - - -
LKCGKMCK_01840 6.08e-12 - - - S - - - Phage-like element PBSX protein XtrA
LKCGKMCK_01841 0.000611 - - - - - - - -
LKCGKMCK_01842 3.89e-66 - - - M - - - ArpU family transcriptional regulator
LKCGKMCK_01846 1.29e-113 yrdC - - Q - - - Isochorismatase family
LKCGKMCK_01849 2.11e-101 - - - L - - - phage terminase small subunit
LKCGKMCK_01850 0.0 - - - S - - - Terminase
LKCGKMCK_01851 3.89e-220 - - - S - - - Phage portal protein
LKCGKMCK_01852 5.33e-102 - - - S - - - peptidase activity
LKCGKMCK_01853 4.29e-201 - - - S - - - capsid protein
LKCGKMCK_01854 3.8e-34 - - - - - - - -
LKCGKMCK_01855 9.84e-51 - - - S - - - Phage gp6-like head-tail connector protein
LKCGKMCK_01856 3.02e-51 - - - S - - - Phage head-tail joining protein
LKCGKMCK_01857 3.42e-66 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LKCGKMCK_01859 5.6e-102 - - - S - - - Phage tail tube protein
LKCGKMCK_01862 0.0 - - - D - - - phage tail tape measure protein
LKCGKMCK_01863 2.06e-143 - - - S - - - Phage tail protein
LKCGKMCK_01864 7.09e-278 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
LKCGKMCK_01865 0.0 - - - S - - - Peptidase_G2, IMC autoproteolytic cleavage domain
LKCGKMCK_01866 3.21e-144 - - - S - - - Domain of unknown function (DUF2479)
LKCGKMCK_01869 6.25e-75 - - - S - - - Bacteriophage holin family
LKCGKMCK_01870 1.07e-160 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LKCGKMCK_01871 9.44e-85 - - - S - - - Immunity protein 70
LKCGKMCK_01872 1.45e-243 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
LKCGKMCK_01873 3.38e-138 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LKCGKMCK_01877 2.95e-14 - - - - - - - -
LKCGKMCK_01878 2.61e-40 - - - - - - - -
LKCGKMCK_01879 7.13e-52 - - - - - - - -
LKCGKMCK_01880 5.4e-105 - - - G - - - regulation of fungal-type cell wall biogenesis
LKCGKMCK_01881 1.97e-186 ynaC - - - - - - -
LKCGKMCK_01882 7.56e-129 ynaD - - J - - - Acetyltransferase (GNAT) domain
LKCGKMCK_01883 1.65e-160 - - - S - - - Domain of unknown function (DUF3885)
LKCGKMCK_01884 1.06e-80 ynaF - - - - - - -
LKCGKMCK_01887 4.32e-110 - - - E - - - phosphoribosylanthranilate isomerase activity
LKCGKMCK_01888 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
LKCGKMCK_01889 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
LKCGKMCK_01890 3.15e-278 xylR - - GK - - - ROK family
LKCGKMCK_01891 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
LKCGKMCK_01892 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
LKCGKMCK_01893 9.1e-148 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
LKCGKMCK_01894 3.64e-313 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LKCGKMCK_01895 3.05e-281 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LKCGKMCK_01896 3.44e-110 - - - S - - - Protein of unknown function (DUF2691)
LKCGKMCK_01897 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
LKCGKMCK_01898 7.54e-22 - - - - - - - -
LKCGKMCK_01901 7.03e-213 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LKCGKMCK_01903 1.55e-172 - - - S - - - Domain of unknown function, YrpD
LKCGKMCK_01906 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
LKCGKMCK_01907 8.92e-96 - - - - - - - -
LKCGKMCK_01908 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
LKCGKMCK_01911 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LKCGKMCK_01912 2.38e-251 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
LKCGKMCK_01913 9.64e-290 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
LKCGKMCK_01914 9.15e-199 yndG - - S - - - DoxX-like family
LKCGKMCK_01915 1.26e-151 - - - S - - - Domain of unknown function (DUF4166)
LKCGKMCK_01916 0.0 yndJ - - S - - - YndJ-like protein
LKCGKMCK_01918 1.68e-177 yndL - - S - - - Replication protein
LKCGKMCK_01919 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
LKCGKMCK_01920 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LKCGKMCK_01922 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LKCGKMCK_01923 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
LKCGKMCK_01924 3.97e-145 yneB - - L - - - resolvase
LKCGKMCK_01925 1.15e-43 ynzC - - S - - - UPF0291 protein
LKCGKMCK_01926 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LKCGKMCK_01927 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
LKCGKMCK_01928 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
LKCGKMCK_01929 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
LKCGKMCK_01930 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
LKCGKMCK_01931 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
LKCGKMCK_01932 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
LKCGKMCK_01933 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
LKCGKMCK_01934 1.21e-86 cotM - - O ko:K06335 - ko00000 Spore coat protein
LKCGKMCK_01935 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
LKCGKMCK_01936 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
LKCGKMCK_01937 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LKCGKMCK_01938 3.74e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LKCGKMCK_01939 9.26e-10 - - - S - - - Fur-regulated basic protein B
LKCGKMCK_01941 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
LKCGKMCK_01942 1.4e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
LKCGKMCK_01943 1.63e-71 yneQ - - - - - - -
LKCGKMCK_01944 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
LKCGKMCK_01945 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LKCGKMCK_01946 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
LKCGKMCK_01947 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LKCGKMCK_01948 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LKCGKMCK_01949 1.82e-18 - - - - - - - -
LKCGKMCK_01950 1.06e-75 ynfC - - - - - - -
LKCGKMCK_01951 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
LKCGKMCK_01952 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
LKCGKMCK_01954 0.0 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
LKCGKMCK_01955 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
LKCGKMCK_01956 1.04e-104 yngA - - S - - - membrane
LKCGKMCK_01957 2.74e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LKCGKMCK_01958 2.01e-134 yngC - - S - - - membrane-associated protein
LKCGKMCK_01959 4.46e-297 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
LKCGKMCK_01960 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LKCGKMCK_01961 1.48e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
LKCGKMCK_01962 7.02e-214 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
LKCGKMCK_01963 1.23e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
LKCGKMCK_01964 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
LKCGKMCK_01965 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LKCGKMCK_01966 1.31e-268 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
LKCGKMCK_01967 4.3e-41 - - - S - - - Family of unknown function (DUF5367)
LKCGKMCK_01968 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
LKCGKMCK_01969 2.12e-84 yngL - - S - - - Protein of unknown function (DUF1360)
LKCGKMCK_01970 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
LKCGKMCK_01971 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKCGKMCK_01972 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKCGKMCK_01973 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKCGKMCK_01974 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKCGKMCK_01975 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
LKCGKMCK_01976 2.54e-245 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LKCGKMCK_01977 9.8e-313 yoeA - - V - - - MATE efflux family protein
LKCGKMCK_01978 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
LKCGKMCK_01980 1.14e-124 - - - L - - - Integrase
LKCGKMCK_01981 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
LKCGKMCK_01982 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
LKCGKMCK_01983 1.3e-202 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_01984 7.23e-238 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LKCGKMCK_01985 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LKCGKMCK_01986 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
LKCGKMCK_01987 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_01988 8.13e-263 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LKCGKMCK_01989 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LKCGKMCK_01990 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
LKCGKMCK_01991 7.94e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LKCGKMCK_01992 8.39e-57 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
LKCGKMCK_01993 1.34e-185 yoxB - - - - - - -
LKCGKMCK_01994 5.91e-125 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LKCGKMCK_01995 1.11e-300 yoaB - - EGP - - - the major facilitator superfamily
LKCGKMCK_01996 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
LKCGKMCK_01997 3.41e-243 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKCGKMCK_01998 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LKCGKMCK_01999 2.08e-44 yoaF - - - - - - -
LKCGKMCK_02001 1.25e-20 - - - - - - - -
LKCGKMCK_02002 8.23e-62 - - - S - - - Protein of unknown function (DUF4025)
LKCGKMCK_02003 0.0 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
LKCGKMCK_02004 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
LKCGKMCK_02005 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
LKCGKMCK_02006 1.79e-145 yoaK - - S - - - Membrane
LKCGKMCK_02007 5e-253 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
LKCGKMCK_02008 5.08e-171 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
LKCGKMCK_02010 1.95e-296 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
LKCGKMCK_02012 9.48e-188 yoaP - - K - - - YoaP-like
LKCGKMCK_02013 7.38e-88 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
LKCGKMCK_02014 2.36e-116 - - - - - - - -
LKCGKMCK_02015 3.63e-218 yoaR - - V - - - vancomycin resistance protein
LKCGKMCK_02016 1.6e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
LKCGKMCK_02017 7.38e-50 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_02018 6.92e-192 yoaT - - S - - - Protein of unknown function (DUF817)
LKCGKMCK_02019 6.67e-203 yoaU - - K - - - LysR substrate binding domain
LKCGKMCK_02020 1.11e-202 yoaV - - EG - - - EamA-like transporter family
LKCGKMCK_02021 6.84e-103 yoaW - - - - - - -
LKCGKMCK_02022 3.88e-153 lin0465 - - S - - - DJ-1/PfpI family
LKCGKMCK_02023 9.26e-218 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
LKCGKMCK_02027 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
LKCGKMCK_02028 1.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
LKCGKMCK_02029 6.27e-51 - - - S - - - TM2 domain
LKCGKMCK_02030 3.92e-76 - - - K - - - Helix-turn-helix
LKCGKMCK_02032 1.21e-90 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
LKCGKMCK_02033 1.92e-162 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
LKCGKMCK_02034 6.85e-229 - - - - - - - -
LKCGKMCK_02035 1.36e-08 - - - - - - - -
LKCGKMCK_02039 6.23e-267 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LKCGKMCK_02041 6.17e-158 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LKCGKMCK_02042 1.52e-79 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LKCGKMCK_02043 2.05e-51 - - - S - - - YolD-like protein
LKCGKMCK_02044 2.08e-64 - - - - - - - -
LKCGKMCK_02045 0.0 - - - K - - - Psort location Cytoplasmic, score
LKCGKMCK_02046 3.58e-202 - - - - - - - -
LKCGKMCK_02047 6.69e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
LKCGKMCK_02048 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LKCGKMCK_02049 4.3e-136 yokH - - G - - - SMI1 / KNR4 family
LKCGKMCK_02050 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
LKCGKMCK_02051 0.0 yobO - - M - - - Pectate lyase superfamily protein
LKCGKMCK_02052 2.21e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
LKCGKMCK_02053 5.23e-175 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
LKCGKMCK_02054 1.29e-183 - - - J - - - FR47-like protein
LKCGKMCK_02055 9.22e-129 yobS - - K - - - Transcriptional regulator
LKCGKMCK_02056 1.34e-169 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LKCGKMCK_02057 1.55e-114 - - - K - - - Bacterial transcription activator, effector binding domain
LKCGKMCK_02058 2.05e-229 yobV - - K - - - WYL domain
LKCGKMCK_02059 7.69e-123 yobW - - - - - - -
LKCGKMCK_02060 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
LKCGKMCK_02061 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LKCGKMCK_02062 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
LKCGKMCK_02063 4.49e-186 - - - - - - - -
LKCGKMCK_02064 1.32e-122 yocC - - - - - - -
LKCGKMCK_02065 1.21e-243 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
LKCGKMCK_02066 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
LKCGKMCK_02067 1.22e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKCGKMCK_02068 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKCGKMCK_02069 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
LKCGKMCK_02070 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
LKCGKMCK_02071 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LKCGKMCK_02072 1.42e-107 yocK - - T - - - general stress protein
LKCGKMCK_02073 3.02e-70 yocL - - - - - - -
LKCGKMCK_02074 7.29e-46 - - - - - - - -
LKCGKMCK_02075 6.6e-115 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LKCGKMCK_02076 2.94e-55 yozN - - - - - - -
LKCGKMCK_02077 1.83e-49 yocN - - - - - - -
LKCGKMCK_02078 2.17e-74 yozO - - S - - - Bacterial PH domain
LKCGKMCK_02079 1.91e-42 yozC - - - - - - -
LKCGKMCK_02080 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LKCGKMCK_02081 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
LKCGKMCK_02082 3.35e-212 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
LKCGKMCK_02083 4.35e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LKCGKMCK_02084 3.31e-214 yocS - - S ko:K03453 - ko00000 -transporter
LKCGKMCK_02085 3.16e-265 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LKCGKMCK_02086 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LKCGKMCK_02087 0.0 yojO - - P - - - Von Willebrand factor
LKCGKMCK_02088 1.33e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
LKCGKMCK_02089 3.62e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LKCGKMCK_02090 1.3e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LKCGKMCK_02091 5.62e-294 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
LKCGKMCK_02092 3.69e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LKCGKMCK_02094 5.06e-314 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
LKCGKMCK_02095 2.49e-194 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKCGKMCK_02096 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
LKCGKMCK_02097 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
LKCGKMCK_02098 1.85e-58 - - - - - - - -
LKCGKMCK_02099 1.21e-209 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
LKCGKMCK_02100 7.43e-107 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
LKCGKMCK_02101 1.95e-14 - - - - - - - -
LKCGKMCK_02102 1.01e-293 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
LKCGKMCK_02103 2.05e-86 iolK - - S - - - tautomerase
LKCGKMCK_02104 1.37e-76 yodB - - K - - - transcriptional
LKCGKMCK_02105 1.92e-140 yodC - - C - - - nitroreductase
LKCGKMCK_02106 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
LKCGKMCK_02107 1.18e-223 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LKCGKMCK_02108 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
LKCGKMCK_02109 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKCGKMCK_02110 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LKCGKMCK_02111 6.38e-168 yodH - - Q - - - Methyltransferase
LKCGKMCK_02112 2.93e-42 yodI - - - - - - -
LKCGKMCK_02113 1.62e-190 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
LKCGKMCK_02114 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
LKCGKMCK_02115 2.08e-12 - - - - - - - -
LKCGKMCK_02116 1.17e-71 yodL - - S - - - YodL-like
LKCGKMCK_02117 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
LKCGKMCK_02118 5.18e-34 yozD - - S - - - YozD-like protein
LKCGKMCK_02120 3.84e-161 yodN - - - - - - -
LKCGKMCK_02121 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
LKCGKMCK_02122 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
LKCGKMCK_02123 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
LKCGKMCK_02124 9.5e-200 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
LKCGKMCK_02125 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
LKCGKMCK_02126 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LKCGKMCK_02128 0.0 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LKCGKMCK_02131 2.06e-186 yiiD - - K ko:K06323 - ko00000 acetyltransferase
LKCGKMCK_02132 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
LKCGKMCK_02133 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
LKCGKMCK_02134 5.57e-86 cgeA - - - ko:K06319 - ko00000 -
LKCGKMCK_02135 2.95e-240 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
LKCGKMCK_02136 4.17e-282 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
LKCGKMCK_02137 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LKCGKMCK_02138 3.52e-105 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
LKCGKMCK_02139 8.41e-134 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LKCGKMCK_02140 4.14e-94 ypoP - - K - - - transcriptional
LKCGKMCK_02141 3.49e-290 mepA - - V - - - MATE efflux family protein
LKCGKMCK_02142 2.13e-40 ypmT - - S - - - Uncharacterized ympT
LKCGKMCK_02143 6.8e-129 ypmS - - S - - - protein conserved in bacteria
LKCGKMCK_02144 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
LKCGKMCK_02145 2.77e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LKCGKMCK_02146 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
LKCGKMCK_02147 3.64e-310 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LKCGKMCK_02148 1.4e-236 yplP - - K - - - Transcriptional regulator
LKCGKMCK_02149 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
LKCGKMCK_02150 1.71e-145 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LKCGKMCK_02151 1.21e-124 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LKCGKMCK_02152 7.27e-203 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LKCGKMCK_02153 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
LKCGKMCK_02154 3.47e-148 ypjP - - S - - - YpjP-like protein
LKCGKMCK_02155 6.15e-187 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
LKCGKMCK_02156 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
LKCGKMCK_02157 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
LKCGKMCK_02158 8.52e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
LKCGKMCK_02159 2.52e-142 yagB - - S ko:K06950 - ko00000 phosphohydrolase
LKCGKMCK_02160 1.89e-115 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
LKCGKMCK_02161 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LKCGKMCK_02162 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
LKCGKMCK_02163 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
LKCGKMCK_02164 1.17e-22 degR - - - - - - -
LKCGKMCK_02165 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
LKCGKMCK_02166 1.54e-37 ypeQ - - S - - - Zinc-finger
LKCGKMCK_02167 4e-163 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
LKCGKMCK_02168 2.4e-138 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LKCGKMCK_02169 1.6e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
LKCGKMCK_02170 5.23e-05 - - - - ko:K06429 - ko00000 -
LKCGKMCK_02171 2.26e-213 ypcP - - L - - - 5'3' exonuclease
LKCGKMCK_02172 1.08e-11 - - - - - - - -
LKCGKMCK_02173 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
LKCGKMCK_02174 0.0 ypbR - - S - - - Dynamin family
LKCGKMCK_02175 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
LKCGKMCK_02176 4.55e-266 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
LKCGKMCK_02177 3.14e-294 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
LKCGKMCK_02178 8.16e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LKCGKMCK_02179 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LKCGKMCK_02180 1e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
LKCGKMCK_02181 2.53e-133 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
LKCGKMCK_02182 6.95e-238 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
LKCGKMCK_02183 1.92e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
LKCGKMCK_02184 1.25e-204 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LKCGKMCK_02185 2.05e-179 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKCGKMCK_02186 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
LKCGKMCK_02188 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
LKCGKMCK_02189 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LKCGKMCK_02190 3.41e-130 ypsA - - S - - - Belongs to the UPF0398 family
LKCGKMCK_02191 7.21e-301 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
LKCGKMCK_02192 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LKCGKMCK_02193 2.34e-113 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
LKCGKMCK_02194 4.33e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LKCGKMCK_02195 8.72e-68 yppG - - S - - - YppG-like protein
LKCGKMCK_02196 9.21e-11 - - - S - - - YppF-like protein
LKCGKMCK_02197 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
LKCGKMCK_02200 4.54e-241 yppC - - S - - - Protein of unknown function (DUF2515)
LKCGKMCK_02201 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LKCGKMCK_02202 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LKCGKMCK_02203 1.43e-121 ypoC - - - - - - -
LKCGKMCK_02204 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LKCGKMCK_02205 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
LKCGKMCK_02206 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
LKCGKMCK_02207 1.07e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LKCGKMCK_02208 2.27e-103 ypmB - - S - - - protein conserved in bacteria
LKCGKMCK_02209 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
LKCGKMCK_02210 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LKCGKMCK_02211 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LKCGKMCK_02212 1.34e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LKCGKMCK_02213 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LKCGKMCK_02214 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LKCGKMCK_02215 1.41e-283 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LKCGKMCK_02216 1.04e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
LKCGKMCK_02217 6.61e-167 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
LKCGKMCK_02218 1.52e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
LKCGKMCK_02219 8.38e-190 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LKCGKMCK_02220 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
LKCGKMCK_02221 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LKCGKMCK_02222 6.84e-183 ypjB - - S - - - sporulation protein
LKCGKMCK_02223 1.63e-125 ypjA - - S - - - membrane
LKCGKMCK_02224 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
LKCGKMCK_02225 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
LKCGKMCK_02226 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
LKCGKMCK_02227 4.75e-101 ypiF - - S - - - Protein of unknown function (DUF2487)
LKCGKMCK_02228 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
LKCGKMCK_02229 5.27e-299 ypiA - - S - - - COG0457 FOG TPR repeat
LKCGKMCK_02230 9.91e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LKCGKMCK_02231 1.71e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
LKCGKMCK_02232 4.5e-259 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LKCGKMCK_02233 3.82e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LKCGKMCK_02234 9.33e-295 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LKCGKMCK_02235 2.82e-153 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
LKCGKMCK_02236 4.18e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
LKCGKMCK_02237 6.08e-230 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LKCGKMCK_02238 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LKCGKMCK_02239 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LKCGKMCK_02240 8.48e-265 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LKCGKMCK_02241 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LKCGKMCK_02242 3.69e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
LKCGKMCK_02243 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LKCGKMCK_02244 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LKCGKMCK_02245 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LKCGKMCK_02246 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
LKCGKMCK_02247 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LKCGKMCK_02248 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
LKCGKMCK_02249 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LKCGKMCK_02250 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LKCGKMCK_02251 9.07e-178 yphF - - - - - - -
LKCGKMCK_02252 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
LKCGKMCK_02253 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
LKCGKMCK_02254 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
LKCGKMCK_02255 8.69e-40 ypzH - - - - - - -
LKCGKMCK_02256 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
LKCGKMCK_02257 2.73e-134 yphA - - - - - - -
LKCGKMCK_02258 1.13e-11 - - - S - - - YpzI-like protein
LKCGKMCK_02259 8.41e-238 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LKCGKMCK_02260 9.5e-263 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
LKCGKMCK_02261 1.73e-147 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
LKCGKMCK_02262 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
LKCGKMCK_02263 4.63e-144 ypfA - - M - - - Flagellar protein YcgR
LKCGKMCK_02264 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
LKCGKMCK_02265 4.88e-208 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
LKCGKMCK_02266 4.33e-154 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
LKCGKMCK_02267 1.62e-227 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
LKCGKMCK_02268 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LKCGKMCK_02269 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LKCGKMCK_02270 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
LKCGKMCK_02271 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
LKCGKMCK_02272 5.04e-148 ypbE - - M - - - Lysin motif
LKCGKMCK_02273 6.13e-129 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
LKCGKMCK_02274 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
LKCGKMCK_02275 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
LKCGKMCK_02276 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
LKCGKMCK_02277 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LKCGKMCK_02278 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKCGKMCK_02279 2.89e-175 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LKCGKMCK_02280 2.7e-257 rsiX - - - - - - -
LKCGKMCK_02281 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LKCGKMCK_02282 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKCGKMCK_02283 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKCGKMCK_02284 4.67e-279 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LKCGKMCK_02285 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
LKCGKMCK_02286 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LKCGKMCK_02287 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LKCGKMCK_02288 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
LKCGKMCK_02289 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
LKCGKMCK_02290 4.11e-273 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LKCGKMCK_02291 6.13e-128 ypuI - - S - - - Protein of unknown function (DUF3907)
LKCGKMCK_02292 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LKCGKMCK_02293 1.33e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LKCGKMCK_02294 3.18e-123 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
LKCGKMCK_02295 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKCGKMCK_02296 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LKCGKMCK_02297 3.12e-292 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LKCGKMCK_02298 1.24e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
LKCGKMCK_02299 1.77e-261 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LKCGKMCK_02300 2.96e-72 ypuD - - - - - - -
LKCGKMCK_02301 1.18e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LKCGKMCK_02302 1.28e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
LKCGKMCK_02304 3.82e-09 - - - S - - - SNARE associated Golgi protein
LKCGKMCK_02306 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LKCGKMCK_02307 2.67e-193 ypuA - - S - - - Secreted protein
LKCGKMCK_02308 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LKCGKMCK_02309 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
LKCGKMCK_02310 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
LKCGKMCK_02311 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
LKCGKMCK_02312 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
LKCGKMCK_02313 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
LKCGKMCK_02314 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
LKCGKMCK_02315 5.72e-144 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
LKCGKMCK_02316 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKCGKMCK_02317 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LKCGKMCK_02318 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
LKCGKMCK_02319 2.89e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LKCGKMCK_02320 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LKCGKMCK_02321 2.89e-295 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
LKCGKMCK_02322 3.91e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
LKCGKMCK_02323 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
LKCGKMCK_02324 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
LKCGKMCK_02325 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LKCGKMCK_02326 3.73e-44 yqkK - - - - - - -
LKCGKMCK_02327 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
LKCGKMCK_02328 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
LKCGKMCK_02329 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
LKCGKMCK_02330 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
LKCGKMCK_02331 3.18e-77 ansR - - K - - - Transcriptional regulator
LKCGKMCK_02332 2.62e-283 yqxK - - L - - - DNA helicase
LKCGKMCK_02333 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
LKCGKMCK_02334 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
LKCGKMCK_02335 9.26e-218 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
LKCGKMCK_02336 1.78e-29 yqkE - - S - - - Protein of unknown function (DUF3886)
LKCGKMCK_02337 4.29e-227 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LKCGKMCK_02338 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
LKCGKMCK_02339 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
LKCGKMCK_02340 2.89e-251 yqkA - - K - - - GrpB protein
LKCGKMCK_02341 5.51e-79 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
LKCGKMCK_02342 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
LKCGKMCK_02343 1.87e-65 yqiX - - S - - - YolD-like protein
LKCGKMCK_02344 4.03e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LKCGKMCK_02346 1.08e-289 yqjV - - G - - - Major Facilitator Superfamily
LKCGKMCK_02348 1.33e-95 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKCGKMCK_02349 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
LKCGKMCK_02350 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
LKCGKMCK_02351 3.41e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LKCGKMCK_02352 3.98e-230 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LKCGKMCK_02353 6.84e-190 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LKCGKMCK_02354 0.0 rocB - - E - - - arginine degradation protein
LKCGKMCK_02355 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LKCGKMCK_02356 3.86e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LKCGKMCK_02357 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LKCGKMCK_02358 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LKCGKMCK_02359 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LKCGKMCK_02360 2.72e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LKCGKMCK_02361 1.77e-32 yqzJ - - - - - - -
LKCGKMCK_02362 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LKCGKMCK_02363 8.77e-184 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
LKCGKMCK_02364 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
LKCGKMCK_02365 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LKCGKMCK_02366 7.17e-99 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
LKCGKMCK_02368 2.41e-128 yqjB - - S - - - protein conserved in bacteria
LKCGKMCK_02369 9.33e-226 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
LKCGKMCK_02370 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LKCGKMCK_02371 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LKCGKMCK_02372 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LKCGKMCK_02373 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
LKCGKMCK_02374 4.23e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LKCGKMCK_02375 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
LKCGKMCK_02376 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
LKCGKMCK_02377 1.57e-296 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LKCGKMCK_02378 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LKCGKMCK_02379 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LKCGKMCK_02380 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LKCGKMCK_02381 1.18e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
LKCGKMCK_02382 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LKCGKMCK_02383 6.35e-201 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
LKCGKMCK_02384 0.0 bkdR - - KT - - - Transcriptional regulator
LKCGKMCK_02385 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
LKCGKMCK_02386 1.07e-209 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LKCGKMCK_02387 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
LKCGKMCK_02388 1.66e-267 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LKCGKMCK_02389 5.16e-270 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
LKCGKMCK_02390 7.2e-201 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
LKCGKMCK_02391 5.7e-281 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LKCGKMCK_02392 3.68e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LKCGKMCK_02393 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
LKCGKMCK_02394 2.26e-37 - - - - - - - -
LKCGKMCK_02395 1.77e-276 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
LKCGKMCK_02397 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LKCGKMCK_02398 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
LKCGKMCK_02399 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
LKCGKMCK_02400 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LKCGKMCK_02401 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
LKCGKMCK_02402 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LKCGKMCK_02403 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LKCGKMCK_02404 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LKCGKMCK_02405 2.5e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LKCGKMCK_02406 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LKCGKMCK_02407 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LKCGKMCK_02408 1.65e-88 yqhY - - S - - - protein conserved in bacteria
LKCGKMCK_02409 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LKCGKMCK_02410 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LKCGKMCK_02411 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
LKCGKMCK_02412 9.25e-150 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
LKCGKMCK_02413 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
LKCGKMCK_02414 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
LKCGKMCK_02415 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
LKCGKMCK_02416 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
LKCGKMCK_02417 6.93e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
LKCGKMCK_02418 1.22e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
LKCGKMCK_02419 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
LKCGKMCK_02420 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LKCGKMCK_02421 3.65e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
LKCGKMCK_02422 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
LKCGKMCK_02423 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
LKCGKMCK_02424 4.42e-222 yqhQ - - S - - - Protein of unknown function (DUF1385)
LKCGKMCK_02425 5.18e-81 yqhP - - - - - - -
LKCGKMCK_02426 1.21e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
LKCGKMCK_02427 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LKCGKMCK_02428 1.12e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LKCGKMCK_02429 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
LKCGKMCK_02430 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LKCGKMCK_02431 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LKCGKMCK_02432 8.13e-263 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
LKCGKMCK_02433 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LKCGKMCK_02434 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
LKCGKMCK_02435 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
LKCGKMCK_02436 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
LKCGKMCK_02437 1.56e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
LKCGKMCK_02438 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
LKCGKMCK_02439 8.73e-160 yqxM - - - ko:K19433 - ko00000 -
LKCGKMCK_02440 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
LKCGKMCK_02441 4.9e-37 yqzE - - S - - - YqzE-like protein
LKCGKMCK_02442 2.55e-55 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
LKCGKMCK_02443 3.44e-65 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
LKCGKMCK_02444 4.35e-79 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
LKCGKMCK_02445 9.7e-94 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
LKCGKMCK_02446 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
LKCGKMCK_02447 1.29e-220 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
LKCGKMCK_02448 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LKCGKMCK_02450 1.51e-233 yqxL - - P - - - Mg2 transporter protein
LKCGKMCK_02451 8.56e-307 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LKCGKMCK_02452 1.06e-193 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKCGKMCK_02454 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
LKCGKMCK_02455 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
LKCGKMCK_02456 5.52e-158 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
LKCGKMCK_02457 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
LKCGKMCK_02458 7.34e-66 yqgV - - S - - - Thiamine-binding protein
LKCGKMCK_02459 5.65e-258 yqgU - - - - - - -
LKCGKMCK_02460 1.06e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
LKCGKMCK_02461 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LKCGKMCK_02462 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
LKCGKMCK_02463 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
LKCGKMCK_02464 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
LKCGKMCK_02465 3.38e-14 yqgO - - - - - - -
LKCGKMCK_02466 2.38e-138 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LKCGKMCK_02467 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LKCGKMCK_02468 1.24e-260 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
LKCGKMCK_02470 3.42e-68 yqzD - - - - - - -
LKCGKMCK_02471 2.92e-98 yqzC - - S - - - YceG-like family
LKCGKMCK_02472 2.71e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LKCGKMCK_02473 2.4e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LKCGKMCK_02474 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
LKCGKMCK_02475 7.43e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
LKCGKMCK_02476 4.51e-206 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LKCGKMCK_02477 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
LKCGKMCK_02478 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
LKCGKMCK_02479 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
LKCGKMCK_02480 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
LKCGKMCK_02481 9.27e-172 yqgB - - S - - - Protein of unknown function (DUF1189)
LKCGKMCK_02482 2.05e-99 yqgA - - - - - - -
LKCGKMCK_02483 2.84e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
LKCGKMCK_02484 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LKCGKMCK_02485 2.04e-81 yqfX - - S - - - membrane
LKCGKMCK_02486 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
LKCGKMCK_02487 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
LKCGKMCK_02488 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LKCGKMCK_02489 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
LKCGKMCK_02490 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LKCGKMCK_02491 5.42e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LKCGKMCK_02492 4.89e-58 yqfQ - - S - - - YqfQ-like protein
LKCGKMCK_02493 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LKCGKMCK_02494 2.27e-270 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LKCGKMCK_02495 2.41e-150 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
LKCGKMCK_02496 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
LKCGKMCK_02497 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LKCGKMCK_02498 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LKCGKMCK_02499 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
LKCGKMCK_02500 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LKCGKMCK_02501 3.29e-144 ccpN - - K - - - CBS domain
LKCGKMCK_02502 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
LKCGKMCK_02503 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
LKCGKMCK_02504 5.26e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
LKCGKMCK_02505 5.29e-27 - - - S - - - YqzL-like protein
LKCGKMCK_02506 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LKCGKMCK_02507 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LKCGKMCK_02508 1.42e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
LKCGKMCK_02509 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LKCGKMCK_02510 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
LKCGKMCK_02512 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
LKCGKMCK_02513 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
LKCGKMCK_02514 2.07e-60 yqfC - - S - - - sporulation protein YqfC
LKCGKMCK_02515 3.13e-79 yqfB - - - - - - -
LKCGKMCK_02516 4.35e-192 yqfA - - S - - - UPF0365 protein
LKCGKMCK_02517 7.97e-292 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
LKCGKMCK_02518 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
LKCGKMCK_02519 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
LKCGKMCK_02520 3.45e-202 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
LKCGKMCK_02521 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
LKCGKMCK_02522 1.01e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LKCGKMCK_02523 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
LKCGKMCK_02524 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LKCGKMCK_02525 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
LKCGKMCK_02526 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LKCGKMCK_02527 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LKCGKMCK_02528 4.3e-278 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
LKCGKMCK_02529 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LKCGKMCK_02530 6.28e-73 yqxA - - S - - - Protein of unknown function (DUF3679)
LKCGKMCK_02531 9.53e-284 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
LKCGKMCK_02532 4.16e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LKCGKMCK_02533 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
LKCGKMCK_02534 2.01e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
LKCGKMCK_02535 2.36e-22 - - - S - - - YqzM-like protein
LKCGKMCK_02536 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LKCGKMCK_02537 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
LKCGKMCK_02538 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
LKCGKMCK_02539 2.69e-189 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LKCGKMCK_02540 9.8e-179 yqeM - - Q - - - Methyltransferase
LKCGKMCK_02541 9.76e-82 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LKCGKMCK_02542 4.81e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
LKCGKMCK_02543 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LKCGKMCK_02544 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
LKCGKMCK_02545 8.44e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LKCGKMCK_02546 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LKCGKMCK_02547 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
LKCGKMCK_02549 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
LKCGKMCK_02550 7.45e-180 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
LKCGKMCK_02551 3.97e-136 yqeD - - S - - - SNARE associated Golgi protein
LKCGKMCK_02552 7.95e-219 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
LKCGKMCK_02553 9.38e-171 - - - - - - - -
LKCGKMCK_02554 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
LKCGKMCK_02555 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKCGKMCK_02556 0.0 - - - L ko:K06400 - ko00000 Recombinase
LKCGKMCK_02557 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
LKCGKMCK_02558 7.13e-233 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
LKCGKMCK_02559 2.56e-104 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKCGKMCK_02560 1.53e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
LKCGKMCK_02561 2.08e-197 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
LKCGKMCK_02562 8.68e-120 - - - S - - - Tetratricopeptide repeat
LKCGKMCK_02565 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
LKCGKMCK_02566 1.66e-136 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
LKCGKMCK_02568 5.4e-80 - - - - - - - -
LKCGKMCK_02570 9.72e-187 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LKCGKMCK_02571 8.36e-89 - - - S - - - Bacteriophage holin family
LKCGKMCK_02572 2.45e-213 xepA - - - - - - -
LKCGKMCK_02573 9.34e-33 - - - - - - - -
LKCGKMCK_02574 1.01e-73 xkdW - - S - - - XkdW protein
LKCGKMCK_02575 2.91e-283 - - - - - - - -
LKCGKMCK_02576 3e-54 - - - - - - - -
LKCGKMCK_02577 4.58e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
LKCGKMCK_02578 1.31e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LKCGKMCK_02579 1.14e-91 xkdS - - S - - - Protein of unknown function (DUF2634)
LKCGKMCK_02580 6.68e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
LKCGKMCK_02581 1.02e-231 xkdQ - - G - - - NLP P60 protein
LKCGKMCK_02582 6.56e-156 xkdP - - S - - - Lysin motif
LKCGKMCK_02583 0.0 xkdO - - L - - - Transglycosylase SLT domain
LKCGKMCK_02584 9.14e-88 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
LKCGKMCK_02586 4.23e-99 xkdM - - S - - - Phage tail tube protein
LKCGKMCK_02587 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
LKCGKMCK_02588 2.52e-36 - - - - - - - -
LKCGKMCK_02589 3.24e-102 yqbJ - - - - - - -
LKCGKMCK_02590 7.59e-123 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LKCGKMCK_02591 7.08e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
LKCGKMCK_02592 7.09e-88 - - - S - - - Protein of unknown function (DUF3199)
LKCGKMCK_02593 2.47e-68 - - - S - - - YqbF, hypothetical protein domain
LKCGKMCK_02594 9.21e-216 xkdG - - S - - - Phage capsid family
LKCGKMCK_02595 5.46e-186 yqbD - - L - - - Putative phage serine protease XkdF
LKCGKMCK_02596 2.13e-149 - - - - - - - -
LKCGKMCK_02597 1.73e-217 - - - S - - - Phage Mu protein F like protein
LKCGKMCK_02598 0.0 yqbA - - S - - - portal protein
LKCGKMCK_02599 0.0 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
LKCGKMCK_02600 2.02e-158 yqaS - - L - - - DNA packaging
LKCGKMCK_02602 1.58e-105 yqaQ - - L - - - Transposase
LKCGKMCK_02603 7.56e-214 - - - - - - - -
LKCGKMCK_02604 2.49e-43 yqaO - - S - - - Phage-like element PBSX protein XtrA
LKCGKMCK_02605 1.38e-97 rusA - - L - - - Endodeoxyribonuclease RusA
LKCGKMCK_02607 4.9e-214 yqaM - - L - - - IstB-like ATP binding protein
LKCGKMCK_02608 1.92e-158 yqaL - - L - - - DnaD domain protein
LKCGKMCK_02609 1.1e-198 recT - - L ko:K07455 - ko00000,ko03400 RecT family
LKCGKMCK_02610 9.38e-229 yqaJ - - L - - - YqaJ-like viral recombinase domain
LKCGKMCK_02614 1.27e-134 - - - - - - - -
LKCGKMCK_02616 3.43e-49 - - - K - - - Helix-turn-helix XRE-family like proteins
LKCGKMCK_02617 1.25e-74 - - - K - - - sequence-specific DNA binding
LKCGKMCK_02619 8.73e-132 yqaC - - F - - - adenylate kinase activity
LKCGKMCK_02620 2.25e-131 xkdA - - E - - - IrrE N-terminal-like domain
LKCGKMCK_02621 1.42e-78 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKCGKMCK_02622 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
LKCGKMCK_02623 7.32e-306 yrkQ - - T - - - Histidine kinase
LKCGKMCK_02624 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
LKCGKMCK_02625 7.53e-283 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
LKCGKMCK_02626 1.33e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
LKCGKMCK_02627 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
LKCGKMCK_02628 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
LKCGKMCK_02629 1.21e-170 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
LKCGKMCK_02630 1.11e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
LKCGKMCK_02631 2.1e-272 yrkH - - P - - - Rhodanese Homology Domain
LKCGKMCK_02632 2.04e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
LKCGKMCK_02633 2.38e-109 yrkE - - O - - - DsrE/DsrF/DrsH-like family
LKCGKMCK_02634 4.38e-52 yrkD - - S - - - protein conserved in bacteria
LKCGKMCK_02635 3.81e-139 yrkC - - G - - - Cupin domain
LKCGKMCK_02636 2.15e-195 bltR - - K - - - helix_turn_helix, mercury resistance
LKCGKMCK_02637 1.31e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
LKCGKMCK_02638 3.73e-109 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
LKCGKMCK_02639 1.58e-301 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LKCGKMCK_02640 7.28e-25 - - - S - - - YrzO-like protein
LKCGKMCK_02641 1.53e-219 yrdR - - EG - - - EamA-like transporter family
LKCGKMCK_02642 1.2e-204 - - - K - - - Transcriptional regulator
LKCGKMCK_02643 2.58e-255 trkA - - P ko:K07222 - ko00000 Oxidoreductase
LKCGKMCK_02644 2.26e-216 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
LKCGKMCK_02645 1.75e-87 yodA - - S - - - tautomerase
LKCGKMCK_02646 2.08e-209 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
LKCGKMCK_02648 2.22e-295 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LKCGKMCK_02649 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
LKCGKMCK_02650 2.29e-176 azlC - - E - - - AzlC protein
LKCGKMCK_02651 1.44e-104 bkdR - - K - - - helix_turn_helix ASNC type
LKCGKMCK_02652 1.07e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
LKCGKMCK_02653 1.75e-295 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LKCGKMCK_02655 7.37e-133 yrdC - - Q - - - Isochorismatase family
LKCGKMCK_02656 2.28e-75 - - - S - - - Protein of unknown function (DUF2568)
LKCGKMCK_02657 1.47e-120 yrdA - - S - - - DinB family
LKCGKMCK_02658 2.66e-215 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
LKCGKMCK_02659 3.79e-249 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LKCGKMCK_02660 8.73e-191 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LKCGKMCK_02661 5.87e-163 yrpD - - S - - - Domain of unknown function, YrpD
LKCGKMCK_02663 9.28e-170 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
LKCGKMCK_02664 1.1e-124 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LKCGKMCK_02665 5.96e-240 yrpG - - C - - - Aldo/keto reductase family
LKCGKMCK_02666 9.19e-287 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LKCGKMCK_02667 5.13e-211 yraN - - K - - - Transcriptional regulator
LKCGKMCK_02668 7.25e-264 yraM - - S - - - PrpF protein
LKCGKMCK_02670 5.73e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
LKCGKMCK_02671 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKCGKMCK_02672 4.9e-200 - - - S - - - Alpha beta hydrolase
LKCGKMCK_02673 6.61e-80 - - - T - - - sh3 domain protein
LKCGKMCK_02674 2.92e-81 - - - T - - - sh3 domain protein
LKCGKMCK_02675 6.62e-87 - - - E - - - Glyoxalase-like domain
LKCGKMCK_02676 4.19e-50 yraG - - - ko:K06440 - ko00000 -
LKCGKMCK_02677 9.61e-84 yraF - - M - - - Spore coat protein
LKCGKMCK_02678 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LKCGKMCK_02679 1.05e-36 yraE - - - ko:K06440 - ko00000 -
LKCGKMCK_02680 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
LKCGKMCK_02681 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
LKCGKMCK_02682 3.03e-40 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
LKCGKMCK_02683 4.3e-256 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
LKCGKMCK_02684 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
LKCGKMCK_02685 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
LKCGKMCK_02686 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
LKCGKMCK_02687 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
LKCGKMCK_02688 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
LKCGKMCK_02689 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
LKCGKMCK_02690 0.0 levR - - K - - - PTS system fructose IIA component
LKCGKMCK_02691 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LKCGKMCK_02692 5.63e-137 yrhP - - E - - - LysE type translocator
LKCGKMCK_02693 5.9e-194 yrhO - - K - - - Archaeal transcriptional regulator TrmB
LKCGKMCK_02694 9.97e-114 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LKCGKMCK_02695 3.67e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
LKCGKMCK_02696 0.0 oatA - - I - - - Acyltransferase family
LKCGKMCK_02697 2.67e-62 yrhK - - S - - - YrhK-like protein
LKCGKMCK_02698 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
LKCGKMCK_02699 1.12e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
LKCGKMCK_02700 1.1e-126 yrhH - - Q - - - methyltransferase
LKCGKMCK_02701 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
LKCGKMCK_02703 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
LKCGKMCK_02704 1.08e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
LKCGKMCK_02705 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
LKCGKMCK_02706 4.26e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
LKCGKMCK_02707 6.93e-49 yrhC - - S - - - YrhC-like protein
LKCGKMCK_02708 4.24e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LKCGKMCK_02709 7.04e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
LKCGKMCK_02710 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LKCGKMCK_02711 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
LKCGKMCK_02712 8.52e-37 yrzA - - S - - - Protein of unknown function (DUF2536)
LKCGKMCK_02713 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
LKCGKMCK_02714 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
LKCGKMCK_02715 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LKCGKMCK_02716 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
LKCGKMCK_02717 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
LKCGKMCK_02718 6.57e-224 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
LKCGKMCK_02719 1.7e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
LKCGKMCK_02720 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LKCGKMCK_02721 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
LKCGKMCK_02722 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LKCGKMCK_02723 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
LKCGKMCK_02724 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LKCGKMCK_02725 3.07e-242 yrrI - - S - - - AI-2E family transporter
LKCGKMCK_02726 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LKCGKMCK_02727 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LKCGKMCK_02728 2.28e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LKCGKMCK_02729 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LKCGKMCK_02730 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
LKCGKMCK_02731 8.4e-42 yrzR - - - - - - -
LKCGKMCK_02732 1.23e-108 yrrD - - S - - - protein conserved in bacteria
LKCGKMCK_02733 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LKCGKMCK_02734 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
LKCGKMCK_02735 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LKCGKMCK_02736 2.67e-272 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LKCGKMCK_02737 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_02738 8.5e-304 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LKCGKMCK_02739 3.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LKCGKMCK_02740 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LKCGKMCK_02741 1.27e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
LKCGKMCK_02743 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
LKCGKMCK_02744 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LKCGKMCK_02745 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LKCGKMCK_02746 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LKCGKMCK_02747 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LKCGKMCK_02748 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
LKCGKMCK_02749 6.51e-114 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
LKCGKMCK_02750 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LKCGKMCK_02751 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
LKCGKMCK_02752 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKCGKMCK_02753 6.34e-147 yrbG - - S - - - membrane
LKCGKMCK_02754 1.07e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
LKCGKMCK_02755 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
LKCGKMCK_02756 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LKCGKMCK_02757 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LKCGKMCK_02758 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
LKCGKMCK_02759 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LKCGKMCK_02760 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LKCGKMCK_02761 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
LKCGKMCK_02762 0.0 csbX - - EGP - - - the major facilitator superfamily
LKCGKMCK_02763 2.77e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
LKCGKMCK_02764 2.32e-152 yrzF - - T - - - serine threonine protein kinase
LKCGKMCK_02766 2.42e-47 - - - S - - - Family of unknown function (DUF5412)
LKCGKMCK_02767 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
LKCGKMCK_02768 8.63e-165 yebC - - K - - - transcriptional regulatory protein
LKCGKMCK_02769 7.28e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LKCGKMCK_02770 1.71e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
LKCGKMCK_02771 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LKCGKMCK_02772 8.17e-208 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
LKCGKMCK_02773 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
LKCGKMCK_02774 1.27e-294 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LKCGKMCK_02775 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
LKCGKMCK_02776 4.99e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
LKCGKMCK_02777 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
LKCGKMCK_02778 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LKCGKMCK_02779 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
LKCGKMCK_02780 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
LKCGKMCK_02781 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
LKCGKMCK_02782 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
LKCGKMCK_02783 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
LKCGKMCK_02784 1.83e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
LKCGKMCK_02785 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
LKCGKMCK_02786 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LKCGKMCK_02787 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
LKCGKMCK_02788 1.91e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
LKCGKMCK_02789 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
LKCGKMCK_02790 8.35e-163 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
LKCGKMCK_02791 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
LKCGKMCK_02792 4.67e-215 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
LKCGKMCK_02793 3.15e-109 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LKCGKMCK_02794 5.8e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LKCGKMCK_02795 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LKCGKMCK_02796 1.53e-35 - - - - - - - -
LKCGKMCK_02797 2.91e-253 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LKCGKMCK_02798 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
LKCGKMCK_02799 8.99e-315 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
LKCGKMCK_02800 6.39e-234 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
LKCGKMCK_02801 1.57e-187 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
LKCGKMCK_02802 2.66e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LKCGKMCK_02803 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
LKCGKMCK_02804 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LKCGKMCK_02805 8.23e-117 ysxD - - - - - - -
LKCGKMCK_02806 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
LKCGKMCK_02807 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LKCGKMCK_02808 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
LKCGKMCK_02809 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LKCGKMCK_02810 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LKCGKMCK_02811 2.73e-240 ysoA - - H - - - Tetratricopeptide repeat
LKCGKMCK_02812 5.35e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LKCGKMCK_02813 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LKCGKMCK_02814 1.06e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LKCGKMCK_02815 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LKCGKMCK_02816 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LKCGKMCK_02817 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
LKCGKMCK_02818 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
LKCGKMCK_02820 3.32e-107 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
LKCGKMCK_02821 1.01e-184 ysnF - - S - - - protein conserved in bacteria
LKCGKMCK_02823 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
LKCGKMCK_02824 1.06e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LKCGKMCK_02825 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LKCGKMCK_02826 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
LKCGKMCK_02827 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LKCGKMCK_02828 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKCGKMCK_02829 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_02830 1.6e-103 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
LKCGKMCK_02831 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
LKCGKMCK_02832 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
LKCGKMCK_02833 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
LKCGKMCK_02834 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
LKCGKMCK_02835 4.83e-276 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LKCGKMCK_02836 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LKCGKMCK_02837 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LKCGKMCK_02838 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
LKCGKMCK_02840 3.02e-228 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
LKCGKMCK_02841 1.28e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
LKCGKMCK_02842 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
LKCGKMCK_02843 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_02844 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LKCGKMCK_02845 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
LKCGKMCK_02846 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LKCGKMCK_02847 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
LKCGKMCK_02848 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
LKCGKMCK_02849 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LKCGKMCK_02850 6.77e-219 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LKCGKMCK_02851 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LKCGKMCK_02852 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LKCGKMCK_02853 7.68e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LKCGKMCK_02854 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
LKCGKMCK_02855 6.71e-265 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
LKCGKMCK_02856 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
LKCGKMCK_02857 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
LKCGKMCK_02858 8.17e-52 ysfE 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 lactoylglutathione lyase activity
LKCGKMCK_02860 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
LKCGKMCK_02861 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
LKCGKMCK_02862 6.34e-192 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
LKCGKMCK_02863 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
LKCGKMCK_02864 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
LKCGKMCK_02865 1.47e-288 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
LKCGKMCK_02866 1.05e-187 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
LKCGKMCK_02867 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LKCGKMCK_02868 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
LKCGKMCK_02869 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
LKCGKMCK_02870 4.21e-243 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
LKCGKMCK_02871 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
LKCGKMCK_02872 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
LKCGKMCK_02873 1.27e-59 ysdA - - S - - - Membrane
LKCGKMCK_02874 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LKCGKMCK_02875 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
LKCGKMCK_02876 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LKCGKMCK_02878 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LKCGKMCK_02879 2.08e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LKCGKMCK_02880 2.9e-168 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
LKCGKMCK_02881 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKCGKMCK_02882 2.07e-191 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
LKCGKMCK_02883 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LKCGKMCK_02884 5.98e-206 ytxC - - S - - - YtxC-like family
LKCGKMCK_02885 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
LKCGKMCK_02886 1.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
LKCGKMCK_02887 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
LKCGKMCK_02888 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LKCGKMCK_02889 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LKCGKMCK_02890 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LKCGKMCK_02891 9.85e-88 ytcD - - K - - - Transcriptional regulator
LKCGKMCK_02892 5.44e-260 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
LKCGKMCK_02893 4.54e-205 ytbE - - S - - - reductase
LKCGKMCK_02894 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LKCGKMCK_02895 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
LKCGKMCK_02896 7e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LKCGKMCK_02897 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LKCGKMCK_02898 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
LKCGKMCK_02899 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKCGKMCK_02900 2.55e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
LKCGKMCK_02901 2.28e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
LKCGKMCK_02902 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LKCGKMCK_02903 9.38e-95 ytwI - - S - - - membrane
LKCGKMCK_02904 2.73e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
LKCGKMCK_02905 5.68e-83 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
LKCGKMCK_02906 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
LKCGKMCK_02907 1.62e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LKCGKMCK_02908 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LKCGKMCK_02909 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LKCGKMCK_02910 6.01e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
LKCGKMCK_02911 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
LKCGKMCK_02912 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
LKCGKMCK_02913 5.12e-112 ytrI - - - - - - -
LKCGKMCK_02914 1.15e-39 - - - - - - - -
LKCGKMCK_02915 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
LKCGKMCK_02916 2.15e-63 ytpI - - S - - - YtpI-like protein
LKCGKMCK_02917 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
LKCGKMCK_02918 2.24e-206 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
LKCGKMCK_02919 2.09e-306 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
LKCGKMCK_02920 1.69e-166 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
LKCGKMCK_02921 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKCGKMCK_02922 5.26e-63 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
LKCGKMCK_02923 1.52e-237 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKCGKMCK_02924 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LKCGKMCK_02925 4.08e-156 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LKCGKMCK_02926 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LKCGKMCK_02927 4.01e-194 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
LKCGKMCK_02928 3.18e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
LKCGKMCK_02929 8.39e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LKCGKMCK_02930 4.99e-223 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
LKCGKMCK_02931 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
LKCGKMCK_02932 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKCGKMCK_02934 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
LKCGKMCK_02935 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
LKCGKMCK_02936 8.14e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
LKCGKMCK_02937 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LKCGKMCK_02938 3.78e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
LKCGKMCK_02939 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LKCGKMCK_02940 2.24e-96 ytfJ - - S - - - Sporulation protein YtfJ
LKCGKMCK_02941 5.03e-150 ytfI - - S - - - Protein of unknown function (DUF2953)
LKCGKMCK_02942 7.05e-113 yteJ - - S - - - RDD family
LKCGKMCK_02943 6.13e-233 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
LKCGKMCK_02944 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LKCGKMCK_02945 0.0 ytcJ - - S - - - amidohydrolase
LKCGKMCK_02946 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LKCGKMCK_02947 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
LKCGKMCK_02948 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LKCGKMCK_02949 1.22e-269 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LKCGKMCK_02950 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LKCGKMCK_02951 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LKCGKMCK_02952 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
LKCGKMCK_02953 2.94e-142 yttP - - K - - - Transcriptional regulator
LKCGKMCK_02954 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
LKCGKMCK_02955 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
LKCGKMCK_02956 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LKCGKMCK_02958 6.47e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LKCGKMCK_02959 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LKCGKMCK_02960 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LKCGKMCK_02961 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
LKCGKMCK_02962 6.51e-293 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
LKCGKMCK_02963 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
LKCGKMCK_02964 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
LKCGKMCK_02965 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
LKCGKMCK_02966 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LKCGKMCK_02967 1.9e-72 ytxJ - - O - - - Protein of unknown function (DUF2847)
LKCGKMCK_02968 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
LKCGKMCK_02969 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LKCGKMCK_02970 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
LKCGKMCK_02971 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LKCGKMCK_02972 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LKCGKMCK_02973 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
LKCGKMCK_02974 3.17e-75 ytpP - - CO - - - Thioredoxin
LKCGKMCK_02975 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
LKCGKMCK_02976 2.24e-262 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
LKCGKMCK_02977 4.06e-68 ytzB - - S - - - small secreted protein
LKCGKMCK_02978 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
LKCGKMCK_02979 2.16e-193 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LKCGKMCK_02980 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LKCGKMCK_02981 9.51e-61 ytzH - - S - - - YtzH-like protein
LKCGKMCK_02982 3.02e-192 ytmP - - M - - - Phosphotransferase
LKCGKMCK_02983 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LKCGKMCK_02984 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LKCGKMCK_02985 4.92e-212 ytlQ - - - - - - -
LKCGKMCK_02986 7.71e-133 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LKCGKMCK_02987 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LKCGKMCK_02988 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
LKCGKMCK_02989 1.73e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
LKCGKMCK_02990 8.45e-263 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
LKCGKMCK_02991 2.4e-169 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LKCGKMCK_02992 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
LKCGKMCK_02993 9.04e-171 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LKCGKMCK_02994 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKCGKMCK_02995 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
LKCGKMCK_02996 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
LKCGKMCK_02997 2.14e-36 yteV - - S - - - Sporulation protein Cse60
LKCGKMCK_02998 1.97e-152 yteU - - S - - - Integral membrane protein
LKCGKMCK_02999 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
LKCGKMCK_03000 5.81e-95 yteS - - G - - - transport
LKCGKMCK_03001 2.23e-286 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
LKCGKMCK_03002 2.27e-221 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
LKCGKMCK_03003 0.0 ytdP - - K - - - Transcriptional regulator
LKCGKMCK_03004 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
LKCGKMCK_03005 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
LKCGKMCK_03006 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
LKCGKMCK_03007 2.64e-287 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LKCGKMCK_03008 4.57e-244 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LKCGKMCK_03009 5.04e-164 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LKCGKMCK_03010 3.73e-284 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LKCGKMCK_03011 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
LKCGKMCK_03012 4.04e-182 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
LKCGKMCK_03013 1.43e-222 - - - S - - - Acetyl xylan esterase (AXE1)
LKCGKMCK_03014 1.12e-244 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_03015 4.68e-315 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LKCGKMCK_03016 2.86e-215 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LKCGKMCK_03017 1.32e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LKCGKMCK_03018 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
LKCGKMCK_03019 1.22e-68 ytwF - - P - - - Sulfurtransferase
LKCGKMCK_03020 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
LKCGKMCK_03021 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
LKCGKMCK_03022 6.61e-184 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
LKCGKMCK_03023 2.98e-269 yttB - - EGP - - - Major facilitator superfamily
LKCGKMCK_03024 2.02e-78 yttA - - S - - - Pfam Transposase IS66
LKCGKMCK_03025 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
LKCGKMCK_03026 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_03027 1.58e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
LKCGKMCK_03028 1.77e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKCGKMCK_03029 5.92e-298 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LKCGKMCK_03030 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_03031 1.07e-189 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
LKCGKMCK_03032 3.35e-222 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LKCGKMCK_03033 1.03e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_03034 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
LKCGKMCK_03036 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
LKCGKMCK_03037 4.06e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
LKCGKMCK_03038 6.76e-137 ytqB - - J - - - Putative rRNA methylase
LKCGKMCK_03039 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
LKCGKMCK_03040 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
LKCGKMCK_03041 8.35e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LKCGKMCK_03042 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LKCGKMCK_03043 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LKCGKMCK_03044 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LKCGKMCK_03045 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LKCGKMCK_03046 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
LKCGKMCK_03047 6.67e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LKCGKMCK_03048 2.77e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LKCGKMCK_03049 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LKCGKMCK_03050 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LKCGKMCK_03051 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
LKCGKMCK_03052 1.59e-81 ytkC - - S - - - Bacteriophage holin family
LKCGKMCK_03053 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
LKCGKMCK_03055 8.26e-96 ytkA - - S - - - YtkA-like
LKCGKMCK_03056 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LKCGKMCK_03057 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
LKCGKMCK_03058 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
LKCGKMCK_03059 2.81e-316 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
LKCGKMCK_03060 2.96e-241 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
LKCGKMCK_03061 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
LKCGKMCK_03062 9.65e-194 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
LKCGKMCK_03063 1.64e-299 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LKCGKMCK_03064 1.83e-180 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LKCGKMCK_03065 1.13e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LKCGKMCK_03066 1.22e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LKCGKMCK_03067 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LKCGKMCK_03068 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LKCGKMCK_03069 5.09e-199 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LKCGKMCK_03070 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LKCGKMCK_03071 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
LKCGKMCK_03072 8.68e-169 yteA - - T - - - COG1734 DnaK suppressor protein
LKCGKMCK_03073 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
LKCGKMCK_03074 2.03e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LKCGKMCK_03075 7.74e-231 ytcB - - M - - - NAD-dependent epimerase dehydratase
LKCGKMCK_03076 3.7e-300 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
LKCGKMCK_03078 1.7e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
LKCGKMCK_03079 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
LKCGKMCK_03080 9.43e-263 cotI - - S ko:K06331 - ko00000 Spore coat protein
LKCGKMCK_03081 1.97e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
LKCGKMCK_03082 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LKCGKMCK_03083 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
LKCGKMCK_03084 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
LKCGKMCK_03085 2.96e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LKCGKMCK_03086 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LKCGKMCK_03108 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LKCGKMCK_03109 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
LKCGKMCK_03110 1.2e-122 - - - M - - - FR47-like protein
LKCGKMCK_03111 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
LKCGKMCK_03112 4.06e-110 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
LKCGKMCK_03113 1.95e-109 yuaE - - S - - - DinB superfamily
LKCGKMCK_03114 8.58e-139 yuaD - - - - - - -
LKCGKMCK_03115 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
LKCGKMCK_03116 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LKCGKMCK_03117 3.53e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
LKCGKMCK_03118 5.83e-118 yuaB - - - - - - -
LKCGKMCK_03119 1.83e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
LKCGKMCK_03120 1.85e-301 - - - P ko:K03498 - ko00000,ko02000 Potassium
LKCGKMCK_03121 3.31e-52 yubF - - S - - - yiaA/B two helix domain
LKCGKMCK_03122 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LKCGKMCK_03123 0.0 yubD - - P - - - Major Facilitator Superfamily
LKCGKMCK_03124 6.82e-114 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
LKCGKMCK_03126 6.02e-183 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LKCGKMCK_03127 3.8e-256 yubA - - S - - - transporter activity
LKCGKMCK_03128 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LKCGKMCK_03129 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
LKCGKMCK_03130 4.94e-73 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
LKCGKMCK_03131 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
LKCGKMCK_03132 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LKCGKMCK_03133 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
LKCGKMCK_03134 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LKCGKMCK_03135 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LKCGKMCK_03136 6.34e-300 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LKCGKMCK_03137 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LKCGKMCK_03138 1.06e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
LKCGKMCK_03139 5e-48 - - - - - - - -
LKCGKMCK_03140 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
LKCGKMCK_03141 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LKCGKMCK_03142 1.07e-301 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LKCGKMCK_03143 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
LKCGKMCK_03144 1.35e-51 - - - - - - - -
LKCGKMCK_03145 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
LKCGKMCK_03146 1.76e-233 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
LKCGKMCK_03147 4.22e-95 yugN - - S - - - YugN-like family
LKCGKMCK_03149 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
LKCGKMCK_03150 5.56e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
LKCGKMCK_03151 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
LKCGKMCK_03152 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
LKCGKMCK_03153 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
LKCGKMCK_03154 6.62e-256 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
LKCGKMCK_03155 6.74e-112 alaR - - K - - - Transcriptional regulator
LKCGKMCK_03156 1.2e-201 yugF - - I - - - Hydrolase
LKCGKMCK_03157 6.7e-56 yugE - - S - - - Domain of unknown function (DUF1871)
LKCGKMCK_03158 2.09e-289 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LKCGKMCK_03159 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKCGKMCK_03160 4.3e-92 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
LKCGKMCK_03161 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
LKCGKMCK_03163 1.96e-245 yuxJ - - EGP - - - Major facilitator superfamily
LKCGKMCK_03164 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
LKCGKMCK_03165 3.31e-98 yuxK - - S - - - protein conserved in bacteria
LKCGKMCK_03166 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
LKCGKMCK_03167 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LKCGKMCK_03168 1.14e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
LKCGKMCK_03169 9.13e-247 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
LKCGKMCK_03170 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_03171 1.57e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LKCGKMCK_03172 1.47e-216 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LKCGKMCK_03173 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
LKCGKMCK_03174 7.06e-22 - - - - - - - -
LKCGKMCK_03175 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LKCGKMCK_03176 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKCGKMCK_03177 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKCGKMCK_03178 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKCGKMCK_03179 7.39e-103 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKCGKMCK_03180 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKCGKMCK_03181 5.97e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
LKCGKMCK_03182 3.18e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
LKCGKMCK_03183 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKCGKMCK_03184 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKCGKMCK_03186 1.4e-209 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
LKCGKMCK_03187 6.29e-10 - - - S - - - DegQ (SacQ) family
LKCGKMCK_03188 9.63e-08 - - - - - - - -
LKCGKMCK_03189 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
LKCGKMCK_03190 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LKCGKMCK_03191 5.65e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
LKCGKMCK_03192 1.32e-88 - - - S - - - Protein of unknown function (DUF1694)
LKCGKMCK_03193 1.63e-52 yueH - - S - - - YueH-like protein
LKCGKMCK_03194 1.23e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
LKCGKMCK_03195 4.72e-245 yueF - - S - - - transporter activity
LKCGKMCK_03196 3.97e-93 - - - S - - - Protein of unknown function (DUF2283)
LKCGKMCK_03197 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
LKCGKMCK_03198 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
LKCGKMCK_03199 6.1e-171 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKCGKMCK_03200 4.37e-97 yueC - - S - - - Family of unknown function (DUF5383)
LKCGKMCK_03201 0.0 yueB - - S - - - type VII secretion protein EsaA
LKCGKMCK_03202 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LKCGKMCK_03203 4.28e-271 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
LKCGKMCK_03204 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
LKCGKMCK_03205 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
LKCGKMCK_03206 1.03e-292 yukF - - QT - - - Transcriptional regulator
LKCGKMCK_03207 4.9e-263 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
LKCGKMCK_03208 2.07e-169 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
LKCGKMCK_03209 1.42e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
LKCGKMCK_03210 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKCGKMCK_03211 3.83e-229 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
LKCGKMCK_03212 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
LKCGKMCK_03213 7.34e-291 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
LKCGKMCK_03214 1.43e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LKCGKMCK_03215 1.55e-213 eSD - - S ko:K07017 - ko00000 Putative esterase
LKCGKMCK_03216 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
LKCGKMCK_03217 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
LKCGKMCK_03218 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
LKCGKMCK_03219 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LKCGKMCK_03220 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
LKCGKMCK_03221 3.28e-151 yuiC - - S - - - protein conserved in bacteria
LKCGKMCK_03222 9.78e-47 yuiB - - S - - - Putative membrane protein
LKCGKMCK_03223 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LKCGKMCK_03224 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
LKCGKMCK_03226 1.15e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LKCGKMCK_03227 2.96e-151 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
LKCGKMCK_03228 6.88e-116 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKCGKMCK_03229 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
LKCGKMCK_03230 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LKCGKMCK_03231 1.54e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LKCGKMCK_03232 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
LKCGKMCK_03233 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LKCGKMCK_03234 6.61e-75 yuzD - - S - - - protein conserved in bacteria
LKCGKMCK_03235 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
LKCGKMCK_03236 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
LKCGKMCK_03237 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LKCGKMCK_03238 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LKCGKMCK_03239 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LKCGKMCK_03240 4.63e-255 yutH - - S - - - Spore coat protein
LKCGKMCK_03241 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
LKCGKMCK_03242 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LKCGKMCK_03243 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
LKCGKMCK_03244 3.2e-63 yutD - - S - - - protein conserved in bacteria
LKCGKMCK_03245 9.45e-145 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LKCGKMCK_03246 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LKCGKMCK_03247 2.66e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
LKCGKMCK_03248 4.25e-172 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
LKCGKMCK_03249 3.41e-65 yunC - - S - - - Domain of unknown function (DUF1805)
LKCGKMCK_03250 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LKCGKMCK_03251 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
LKCGKMCK_03252 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
LKCGKMCK_03253 2.72e-82 yunG - - - - - - -
LKCGKMCK_03254 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LKCGKMCK_03255 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
LKCGKMCK_03256 1.46e-300 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
LKCGKMCK_03257 1.65e-285 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
LKCGKMCK_03258 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
LKCGKMCK_03259 1.41e-79 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
LKCGKMCK_03260 1.3e-126 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
LKCGKMCK_03261 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
LKCGKMCK_03262 4.85e-194 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
LKCGKMCK_03263 2.62e-144 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
LKCGKMCK_03264 5.12e-243 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LKCGKMCK_03266 8.51e-306 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LKCGKMCK_03267 4.9e-303 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LKCGKMCK_03268 6.53e-218 bsn - - L - - - Ribonuclease
LKCGKMCK_03269 2.95e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKCGKMCK_03270 7.46e-176 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
LKCGKMCK_03271 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
LKCGKMCK_03272 1.94e-216 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
LKCGKMCK_03273 1.24e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LKCGKMCK_03274 2.46e-308 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
LKCGKMCK_03275 2.24e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
LKCGKMCK_03276 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
LKCGKMCK_03277 1.42e-268 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
LKCGKMCK_03279 3.35e-56 - - - - - - - -
LKCGKMCK_03280 2.14e-87 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKCGKMCK_03281 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
LKCGKMCK_03282 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
LKCGKMCK_03283 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LKCGKMCK_03284 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
LKCGKMCK_03285 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LKCGKMCK_03286 5.44e-81 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LKCGKMCK_03287 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
LKCGKMCK_03288 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
LKCGKMCK_03289 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LKCGKMCK_03290 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
LKCGKMCK_03291 2e-73 yusE - - CO - - - Thioredoxin
LKCGKMCK_03292 1.32e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
LKCGKMCK_03293 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
LKCGKMCK_03294 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LKCGKMCK_03295 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
LKCGKMCK_03296 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
LKCGKMCK_03297 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
LKCGKMCK_03298 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
LKCGKMCK_03299 2.86e-14 - - - S - - - YuzL-like protein
LKCGKMCK_03300 2.09e-212 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
LKCGKMCK_03301 2.23e-54 - - - - - - - -
LKCGKMCK_03302 2.12e-70 yusN - - M - - - Coat F domain
LKCGKMCK_03303 3.83e-99 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
LKCGKMCK_03304 0.0 yusP - - P - - - Major facilitator superfamily
LKCGKMCK_03305 1.76e-86 yusQ - - S - - - Tautomerase enzyme
LKCGKMCK_03306 5.64e-84 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LKCGKMCK_03307 4.48e-67 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LKCGKMCK_03308 1.52e-206 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
LKCGKMCK_03309 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
LKCGKMCK_03310 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LKCGKMCK_03311 2.01e-87 - - - S - - - YusW-like protein
LKCGKMCK_03312 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
LKCGKMCK_03313 1.21e-41 pepF2 - - E - - - COG1164 Oligoendopeptidase F
LKCGKMCK_03314 6.65e-198 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LKCGKMCK_03315 1.07e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
LKCGKMCK_03316 9.63e-306 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKCGKMCK_03317 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKCGKMCK_03318 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKCGKMCK_03319 3.06e-204 yuxN - - K - - - Transcriptional regulator
LKCGKMCK_03320 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LKCGKMCK_03321 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
LKCGKMCK_03322 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LKCGKMCK_03323 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
LKCGKMCK_03324 3.48e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
LKCGKMCK_03325 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKCGKMCK_03326 4.06e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKCGKMCK_03327 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
LKCGKMCK_03328 6.57e-178 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
LKCGKMCK_03329 4.22e-144 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
LKCGKMCK_03330 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
LKCGKMCK_03331 1.13e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LKCGKMCK_03332 8.21e-133 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
LKCGKMCK_03333 0.0 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
LKCGKMCK_03334 3.29e-237 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKCGKMCK_03335 5.15e-219 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
LKCGKMCK_03336 5.21e-182 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LKCGKMCK_03337 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
LKCGKMCK_03338 0.0 yvrG - - T - - - Histidine kinase
LKCGKMCK_03339 2.08e-169 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKCGKMCK_03340 5.07e-32 - - - - - - - -
LKCGKMCK_03341 6.74e-126 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
LKCGKMCK_03342 3.46e-26 - - - S - - - YvrJ protein family
LKCGKMCK_03343 1.59e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
LKCGKMCK_03344 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
LKCGKMCK_03345 1.17e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LKCGKMCK_03346 1.62e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_03347 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
LKCGKMCK_03348 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LKCGKMCK_03349 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKCGKMCK_03350 1.48e-237 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKCGKMCK_03351 1.14e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LKCGKMCK_03353 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
LKCGKMCK_03354 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
LKCGKMCK_03355 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
LKCGKMCK_03356 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
LKCGKMCK_03357 5.58e-218 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
LKCGKMCK_03358 6.57e-179 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
LKCGKMCK_03359 6.08e-154 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
LKCGKMCK_03360 4.54e-203 yvgN - - S - - - reductase
LKCGKMCK_03361 7.97e-113 yvgO - - - - - - -
LKCGKMCK_03362 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
LKCGKMCK_03363 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LKCGKMCK_03364 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LKCGKMCK_03365 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LKCGKMCK_03366 3.88e-140 yvgT - - S - - - membrane
LKCGKMCK_03367 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
LKCGKMCK_03368 3.45e-137 bdbD - - O - - - Thioredoxin
LKCGKMCK_03369 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
LKCGKMCK_03370 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LKCGKMCK_03371 3.66e-41 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
LKCGKMCK_03372 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
LKCGKMCK_03373 7.89e-254 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LKCGKMCK_03374 3.59e-154 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LKCGKMCK_03375 0.0 - - - S - - - Fusaric acid resistance protein-like
LKCGKMCK_03376 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
LKCGKMCK_03377 4.28e-72 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
LKCGKMCK_03378 8.9e-131 - - - K - - - Bacterial regulatory proteins, tetR family
LKCGKMCK_03379 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LKCGKMCK_03381 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LKCGKMCK_03382 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LKCGKMCK_03383 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
LKCGKMCK_03384 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
LKCGKMCK_03385 4.03e-196 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
LKCGKMCK_03386 3.44e-48 yvzC - - K - - - transcriptional
LKCGKMCK_03387 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
LKCGKMCK_03388 1.19e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
LKCGKMCK_03389 3.85e-72 yvaP - - K - - - transcriptional
LKCGKMCK_03390 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LKCGKMCK_03391 2.26e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LKCGKMCK_03392 2.89e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LKCGKMCK_03393 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LKCGKMCK_03394 6.29e-272 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LKCGKMCK_03395 1.15e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
LKCGKMCK_03396 2.75e-11 - - - S - - - Sporulation delaying protein SdpA
LKCGKMCK_03397 4.79e-224 - - - - - - - -
LKCGKMCK_03399 8.32e-133 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
LKCGKMCK_03400 9.63e-60 sdpR - - K - - - transcriptional
LKCGKMCK_03401 1.03e-146 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LKCGKMCK_03402 2.58e-223 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LKCGKMCK_03403 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LKCGKMCK_03404 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LKCGKMCK_03405 1.74e-130 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
LKCGKMCK_03406 9.68e-136 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
LKCGKMCK_03407 1.03e-145 yvbH - - S - - - YvbH-like oligomerisation region
LKCGKMCK_03408 2.38e-158 yvbI - - M - - - Membrane
LKCGKMCK_03409 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
LKCGKMCK_03410 2.4e-106 yvbK - - K - - - acetyltransferase
LKCGKMCK_03411 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LKCGKMCK_03412 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
LKCGKMCK_03413 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LKCGKMCK_03414 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
LKCGKMCK_03415 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LKCGKMCK_03416 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LKCGKMCK_03417 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LKCGKMCK_03418 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
LKCGKMCK_03419 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKCGKMCK_03420 3.45e-206 yvbU - - K - - - Transcriptional regulator
LKCGKMCK_03421 2.37e-199 yvbV - - EG - - - EamA-like transporter family
LKCGKMCK_03422 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LKCGKMCK_03423 2.68e-252 - - - S - - - Glycosyl hydrolase
LKCGKMCK_03424 1.45e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LKCGKMCK_03425 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LKCGKMCK_03426 5.47e-176 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LKCGKMCK_03427 7.53e-137 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKCGKMCK_03428 1.76e-257 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKCGKMCK_03429 2.48e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
LKCGKMCK_03430 1.03e-209 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
LKCGKMCK_03431 7.25e-201 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
LKCGKMCK_03432 1.52e-265 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
LKCGKMCK_03433 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
LKCGKMCK_03434 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
LKCGKMCK_03435 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
LKCGKMCK_03436 1.3e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
LKCGKMCK_03437 2.05e-295 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
LKCGKMCK_03438 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_03439 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
LKCGKMCK_03440 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LKCGKMCK_03441 2.57e-308 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LKCGKMCK_03442 5.69e-44 yvfG - - S - - - YvfG protein
LKCGKMCK_03443 1.85e-241 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
LKCGKMCK_03444 1.2e-284 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
LKCGKMCK_03445 6.53e-81 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
LKCGKMCK_03446 1.65e-141 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LKCGKMCK_03447 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKCGKMCK_03448 4.44e-251 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LKCGKMCK_03449 5.09e-264 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
LKCGKMCK_03450 6.3e-251 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
LKCGKMCK_03451 8.82e-265 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
LKCGKMCK_03452 7.49e-280 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LKCGKMCK_03453 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
LKCGKMCK_03454 2.95e-286 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
LKCGKMCK_03455 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LKCGKMCK_03456 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
LKCGKMCK_03457 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
LKCGKMCK_03458 2.15e-99 - - - K ko:K19417 - ko00000,ko03000 transcriptional
LKCGKMCK_03459 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
LKCGKMCK_03461 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
LKCGKMCK_03462 5.1e-64 - - - S - - - Protein of unknown function (DUF3237)
LKCGKMCK_03463 1.51e-163 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LKCGKMCK_03464 0.0 pbpE - - V - - - Beta-lactamase
LKCGKMCK_03465 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
LKCGKMCK_03466 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
LKCGKMCK_03467 0.0 ybeC - - E - - - amino acid
LKCGKMCK_03468 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
LKCGKMCK_03469 6.31e-68 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LKCGKMCK_03470 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
LKCGKMCK_03471 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
LKCGKMCK_03472 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
LKCGKMCK_03473 1.99e-235 - - - S - - - Patatin-like phospholipase
LKCGKMCK_03475 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LKCGKMCK_03476 1.01e-156 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LKCGKMCK_03477 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LKCGKMCK_03478 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
LKCGKMCK_03479 2.42e-203 malA - - S - - - Protein of unknown function (DUF1189)
LKCGKMCK_03480 1.18e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
LKCGKMCK_03481 2.12e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
LKCGKMCK_03482 1.03e-302 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
LKCGKMCK_03483 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
LKCGKMCK_03484 2.28e-223 yvdE - - K - - - Transcriptional regulator
LKCGKMCK_03485 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
LKCGKMCK_03486 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
LKCGKMCK_03487 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
LKCGKMCK_03488 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
LKCGKMCK_03489 1.4e-235 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKCGKMCK_03490 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
LKCGKMCK_03491 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_03492 1.68e-252 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
LKCGKMCK_03493 4.67e-172 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKCGKMCK_03494 1.37e-45 - - - - - - - -
LKCGKMCK_03495 5.24e-188 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
LKCGKMCK_03496 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
LKCGKMCK_03497 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LKCGKMCK_03498 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
LKCGKMCK_03499 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
LKCGKMCK_03500 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LKCGKMCK_03501 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LKCGKMCK_03502 3.05e-190 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
LKCGKMCK_03503 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
LKCGKMCK_03504 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
LKCGKMCK_03506 0.0 - - - - - - - -
LKCGKMCK_03507 6.36e-172 - - - - - - - -
LKCGKMCK_03508 2.61e-146 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
LKCGKMCK_03509 9.74e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LKCGKMCK_03510 1.44e-170 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LKCGKMCK_03511 7.21e-150 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LKCGKMCK_03512 4.96e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
LKCGKMCK_03513 1.19e-297 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LKCGKMCK_03514 9.09e-149 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LKCGKMCK_03515 2.07e-282 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LKCGKMCK_03516 2.14e-179 yvpB - - NU - - - protein conserved in bacteria
LKCGKMCK_03517 5.68e-156 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
LKCGKMCK_03518 5.29e-121 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
LKCGKMCK_03519 4.51e-155 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LKCGKMCK_03520 3.19e-212 yvoD - - P - - - COG0370 Fe2 transport system protein B
LKCGKMCK_03521 3.18e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LKCGKMCK_03522 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LKCGKMCK_03523 2.25e-284 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
LKCGKMCK_03524 1.39e-171 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LKCGKMCK_03525 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
LKCGKMCK_03526 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
LKCGKMCK_03527 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKCGKMCK_03528 1.61e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LKCGKMCK_03529 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
LKCGKMCK_03530 6.2e-114 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKCGKMCK_03531 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
LKCGKMCK_03532 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
LKCGKMCK_03533 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
LKCGKMCK_03534 5.8e-221 yvlB - - S - - - Putative adhesin
LKCGKMCK_03535 8.09e-65 yvlA - - - - - - -
LKCGKMCK_03536 2.73e-46 yvkN - - - - - - -
LKCGKMCK_03537 2.57e-104 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LKCGKMCK_03538 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LKCGKMCK_03539 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LKCGKMCK_03540 2.54e-42 csbA - - S - - - protein conserved in bacteria
LKCGKMCK_03541 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
LKCGKMCK_03543 1.43e-131 yvkB - - K - - - Transcriptional regulator
LKCGKMCK_03544 5.47e-298 yvkA - - P - - - -transporter
LKCGKMCK_03545 3.86e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKCGKMCK_03546 1.38e-73 swrA - - S - - - Swarming motility protein
LKCGKMCK_03547 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LKCGKMCK_03548 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LKCGKMCK_03549 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
LKCGKMCK_03550 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
LKCGKMCK_03551 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LKCGKMCK_03552 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LKCGKMCK_03553 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LKCGKMCK_03554 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LKCGKMCK_03555 9.14e-88 - - - - - - - -
LKCGKMCK_03556 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
LKCGKMCK_03557 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
LKCGKMCK_03558 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LKCGKMCK_03559 1.1e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
LKCGKMCK_03560 8.01e-202 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LKCGKMCK_03561 2.58e-41 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LKCGKMCK_03562 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LKCGKMCK_03563 4.19e-93 yviE - - - - - - -
LKCGKMCK_03564 1.97e-199 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
LKCGKMCK_03565 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
LKCGKMCK_03566 3.5e-102 yvyG - - NOU - - - FlgN protein
LKCGKMCK_03567 1.06e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
LKCGKMCK_03568 1.83e-96 yvyF - - S - - - flagellar protein
LKCGKMCK_03569 9.99e-166 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
LKCGKMCK_03570 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
LKCGKMCK_03571 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LKCGKMCK_03572 2.15e-199 degV - - S - - - protein conserved in bacteria
LKCGKMCK_03573 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKCGKMCK_03574 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LKCGKMCK_03575 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
LKCGKMCK_03576 3.99e-225 yvhJ - - K - - - Transcriptional regulator
LKCGKMCK_03577 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LKCGKMCK_03578 3.3e-303 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
LKCGKMCK_03579 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
LKCGKMCK_03580 6.04e-149 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
LKCGKMCK_03581 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
LKCGKMCK_03582 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LKCGKMCK_03583 8.77e-283 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
LKCGKMCK_03584 2.58e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKCGKMCK_03585 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LKCGKMCK_03586 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LKCGKMCK_03587 0.0 lytB - - D - - - Stage II sporulation protein
LKCGKMCK_03588 3.26e-50 - - - - - - - -
LKCGKMCK_03589 2.77e-219 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LKCGKMCK_03590 6.61e-278 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LKCGKMCK_03591 1.78e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LKCGKMCK_03592 0.0 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LKCGKMCK_03593 0.0 - - - M - - - Glycosyltransferase like family 2
LKCGKMCK_03594 5.43e-05 - 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase-like
LKCGKMCK_03595 2.13e-127 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LKCGKMCK_03596 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LKCGKMCK_03597 2.06e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
LKCGKMCK_03598 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LKCGKMCK_03599 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
LKCGKMCK_03600 3.82e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
LKCGKMCK_03601 1.9e-185 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LKCGKMCK_03602 3.8e-273 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LKCGKMCK_03603 0.0 - - - - - - - -
LKCGKMCK_03604 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LKCGKMCK_03605 1.16e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LKCGKMCK_03606 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LKCGKMCK_03607 1.24e-256 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
LKCGKMCK_03608 2.29e-275 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
LKCGKMCK_03609 8.19e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LKCGKMCK_03610 1.48e-222 ywtF_2 - - K - - - Transcriptional regulator
LKCGKMCK_03611 7.24e-205 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LKCGKMCK_03612 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LKCGKMCK_03613 2.29e-29 ywtC - - - - - - -
LKCGKMCK_03614 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
LKCGKMCK_03615 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
LKCGKMCK_03616 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
LKCGKMCK_03617 2.3e-228 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
LKCGKMCK_03618 6.44e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LKCGKMCK_03619 5.6e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LKCGKMCK_03620 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LKCGKMCK_03621 2.87e-204 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LKCGKMCK_03622 1.34e-205 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
LKCGKMCK_03623 2.49e-122 batE - - T - - - Sh3 type 3 domain protein
LKCGKMCK_03624 9.2e-64 ywsA - - S - - - Protein of unknown function (DUF3892)
LKCGKMCK_03625 2.15e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
LKCGKMCK_03626 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
LKCGKMCK_03627 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LKCGKMCK_03628 3.36e-218 alsR - - K - - - LysR substrate binding domain
LKCGKMCK_03629 1.68e-281 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LKCGKMCK_03630 9.09e-164 ywrJ - - - - - - -
LKCGKMCK_03631 1.02e-196 cotB - - - ko:K06325 - ko00000 -
LKCGKMCK_03632 1.12e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
LKCGKMCK_03633 2.17e-16 - - - - - - - -
LKCGKMCK_03634 4.35e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LKCGKMCK_03635 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
LKCGKMCK_03636 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
LKCGKMCK_03637 4.83e-108 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
LKCGKMCK_03638 5.52e-133 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
LKCGKMCK_03639 3.66e-115 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
LKCGKMCK_03641 3.83e-132 ywqN - - S - - - NAD(P)H-dependent
LKCGKMCK_03642 1.16e-209 - - - K - - - Transcriptional regulator
LKCGKMCK_03643 7.78e-176 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
LKCGKMCK_03644 1.36e-71 - - - S - - - MORN repeat variant
LKCGKMCK_03645 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
LKCGKMCK_03646 2.17e-52 ywqI - - S - - - Family of unknown function (DUF5344)
LKCGKMCK_03648 2.52e-197 ywqG - - S - - - Domain of unknown function (DUF1963)
LKCGKMCK_03649 9.82e-315 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LKCGKMCK_03650 3.16e-183 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
LKCGKMCK_03651 4.51e-156 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
LKCGKMCK_03652 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
LKCGKMCK_03653 3.6e-25 - - - - - - - -
LKCGKMCK_03654 0.0 ywqB - - S - - - SWIM zinc finger
LKCGKMCK_03655 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LKCGKMCK_03656 4.53e-203 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LKCGKMCK_03657 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LKCGKMCK_03658 1.04e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
LKCGKMCK_03659 5.26e-88 ywpG - - - - - - -
LKCGKMCK_03660 8.81e-89 ywpF - - S - - - YwpF-like protein
LKCGKMCK_03661 4.63e-68 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
LKCGKMCK_03662 2.55e-197 ywpD - - T - - - Histidine kinase
LKCGKMCK_03663 1.13e-79 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LKCGKMCK_03664 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LKCGKMCK_03665 5.45e-257 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
LKCGKMCK_03666 4.1e-182 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
LKCGKMCK_03667 6.18e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
LKCGKMCK_03668 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
LKCGKMCK_03669 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
LKCGKMCK_03670 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
LKCGKMCK_03671 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LKCGKMCK_03672 1.02e-312 ywoF - - P - - - Right handed beta helix region
LKCGKMCK_03673 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
LKCGKMCK_03674 8e-309 ywoD - - EGP - - - Major facilitator superfamily
LKCGKMCK_03675 2.56e-134 yjgF - - Q - - - Isochorismatase family
LKCGKMCK_03676 3.04e-102 - - - - - - - -
LKCGKMCK_03677 1.6e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
LKCGKMCK_03678 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
LKCGKMCK_03679 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
LKCGKMCK_03680 1.63e-95 ywnJ - - S - - - VanZ like family
LKCGKMCK_03681 2.13e-175 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
LKCGKMCK_03682 1.55e-116 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
LKCGKMCK_03683 3.28e-22 ywnC - - S - - - Family of unknown function (DUF5362)
LKCGKMCK_03684 7.07e-92 ywnF - - S - - - Family of unknown function (DUF5392)
LKCGKMCK_03685 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LKCGKMCK_03686 3.41e-184 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
LKCGKMCK_03687 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
LKCGKMCK_03688 1.29e-148 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
LKCGKMCK_03689 4.58e-85 ywnA - - K - - - Transcriptional regulator
LKCGKMCK_03690 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LKCGKMCK_03691 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
LKCGKMCK_03692 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
LKCGKMCK_03694 1.11e-21 csbD - - K - - - CsbD-like
LKCGKMCK_03695 1.12e-109 ywmF - - S - - - Peptidase M50
LKCGKMCK_03696 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LKCGKMCK_03697 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LKCGKMCK_03698 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LKCGKMCK_03700 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LKCGKMCK_03701 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LKCGKMCK_03702 3.72e-238 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
LKCGKMCK_03703 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LKCGKMCK_03704 2.39e-174 ywmB - - S - - - TATA-box binding
LKCGKMCK_03705 4.54e-45 ywzB - - S - - - membrane
LKCGKMCK_03706 6.12e-115 ywmA - - - - - - -
LKCGKMCK_03707 1.04e-76 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
LKCGKMCK_03708 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LKCGKMCK_03709 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LKCGKMCK_03710 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LKCGKMCK_03711 2.89e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LKCGKMCK_03712 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LKCGKMCK_03713 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LKCGKMCK_03714 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
LKCGKMCK_03715 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
LKCGKMCK_03716 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LKCGKMCK_03717 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LKCGKMCK_03718 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
LKCGKMCK_03719 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
LKCGKMCK_03720 5.75e-103 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LKCGKMCK_03721 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
LKCGKMCK_03722 4.44e-252 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LKCGKMCK_03723 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
LKCGKMCK_03724 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
LKCGKMCK_03725 1.67e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
LKCGKMCK_03727 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LKCGKMCK_03728 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LKCGKMCK_03729 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKCGKMCK_03730 6.26e-119 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
LKCGKMCK_03731 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
LKCGKMCK_03732 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
LKCGKMCK_03733 8.53e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
LKCGKMCK_03734 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
LKCGKMCK_03735 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LKCGKMCK_03736 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
LKCGKMCK_03737 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LKCGKMCK_03738 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LKCGKMCK_03739 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
LKCGKMCK_03740 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
LKCGKMCK_03741 3.31e-120 ywjG - - S - - - Domain of unknown function (DUF2529)
LKCGKMCK_03742 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LKCGKMCK_03743 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LKCGKMCK_03744 2.1e-269 acdA - - I - - - acyl-CoA dehydrogenase
LKCGKMCK_03745 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
LKCGKMCK_03746 8.56e-290 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LKCGKMCK_03747 4.88e-236 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
LKCGKMCK_03748 1.32e-57 ywjC - - - - - - -
LKCGKMCK_03749 1.35e-124 ywjB - - H - - - RibD C-terminal domain
LKCGKMCK_03750 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
LKCGKMCK_03751 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LKCGKMCK_03752 1.02e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
LKCGKMCK_03753 6.32e-128 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
LKCGKMCK_03754 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
LKCGKMCK_03755 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LKCGKMCK_03756 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
LKCGKMCK_03757 1.57e-180 ywiC - - S - - - YwiC-like protein
LKCGKMCK_03758 3.98e-169 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
LKCGKMCK_03759 3.39e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
LKCGKMCK_03760 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
LKCGKMCK_03761 4.64e-96 ywiB - - S - - - protein conserved in bacteria
LKCGKMCK_03762 3.71e-12 - - - S - - - Bacteriocin subtilosin A
LKCGKMCK_03763 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
LKCGKMCK_03765 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LKCGKMCK_03766 1.07e-300 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
LKCGKMCK_03767 7.55e-280 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
LKCGKMCK_03768 0.0 - - - L - - - Peptidase, M16
LKCGKMCK_03770 0.0 ywhL - - CO - - - amine dehydrogenase activity
LKCGKMCK_03771 2.36e-291 ywhK - - CO - - - amine dehydrogenase activity
LKCGKMCK_03772 2.88e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LKCGKMCK_03774 6.61e-110 - - - S - - - Aminoacyl-tRNA editing domain
LKCGKMCK_03775 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
LKCGKMCK_03776 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LKCGKMCK_03777 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LKCGKMCK_03778 1.92e-123 ywhD - - S - - - YwhD family
LKCGKMCK_03779 3.29e-154 ywhC - - S - - - Peptidase family M50
LKCGKMCK_03780 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
LKCGKMCK_03781 1.76e-94 ywhA - - K - - - Transcriptional regulator
LKCGKMCK_03782 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LKCGKMCK_03784 2.66e-307 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
LKCGKMCK_03785 1.1e-103 yffB - - K - - - Transcriptional regulator
LKCGKMCK_03786 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
LKCGKMCK_03787 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
LKCGKMCK_03788 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
LKCGKMCK_03789 5.65e-147 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
LKCGKMCK_03790 1.57e-204 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
LKCGKMCK_03791 2.15e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LKCGKMCK_03792 9.56e-212 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_03793 7.1e-226 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
LKCGKMCK_03794 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
LKCGKMCK_03795 3.52e-178 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
LKCGKMCK_03796 1.89e-298 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
LKCGKMCK_03797 1.36e-268 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
LKCGKMCK_03798 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
LKCGKMCK_03799 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKCGKMCK_03800 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
LKCGKMCK_03801 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
LKCGKMCK_03802 1.89e-275 ywfA - - EGP - - - -transporter
LKCGKMCK_03803 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LKCGKMCK_03804 0.0 rocB - - E - - - arginine degradation protein
LKCGKMCK_03805 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
LKCGKMCK_03806 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LKCGKMCK_03807 1.1e-102 - - - - - - - -
LKCGKMCK_03808 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
LKCGKMCK_03809 2.44e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LKCGKMCK_03810 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LKCGKMCK_03811 2.6e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LKCGKMCK_03812 2.54e-243 spsG - - M - - - Spore Coat
LKCGKMCK_03813 4.64e-169 spsF - - M ko:K07257 - ko00000 Spore Coat
LKCGKMCK_03814 6.8e-272 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
LKCGKMCK_03815 1.04e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
LKCGKMCK_03816 4.54e-285 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
LKCGKMCK_03817 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
LKCGKMCK_03818 4.87e-188 spsA - - M - - - Spore Coat
LKCGKMCK_03819 7.61e-114 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LKCGKMCK_03820 1.59e-78 ywdK - - S - - - small membrane protein
LKCGKMCK_03821 4.57e-304 ywdJ - - F - - - Xanthine uracil
LKCGKMCK_03822 9.23e-65 ywdI - - S - - - Family of unknown function (DUF5327)
LKCGKMCK_03823 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LKCGKMCK_03824 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LKCGKMCK_03825 5.69e-193 ywdF - - S - - - Glycosyltransferase like family 2
LKCGKMCK_03827 8.74e-146 ywdD - - - - - - -
LKCGKMCK_03828 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
LKCGKMCK_03829 5.43e-188 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LKCGKMCK_03830 6.19e-39 ywdA - - - - - - -
LKCGKMCK_03831 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LKCGKMCK_03832 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKCGKMCK_03833 2.91e-180 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
LKCGKMCK_03834 4.49e-194 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
LKCGKMCK_03836 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LKCGKMCK_03837 4.19e-239 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKCGKMCK_03838 1.98e-179 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
LKCGKMCK_03839 8.89e-269 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
LKCGKMCK_03840 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
LKCGKMCK_03841 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
LKCGKMCK_03842 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
LKCGKMCK_03843 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LKCGKMCK_03844 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LKCGKMCK_03845 5.11e-49 ydaS - - S - - - membrane
LKCGKMCK_03846 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LKCGKMCK_03847 5.56e-291 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LKCGKMCK_03848 3.33e-77 gtcA - - S - - - GtrA-like protein
LKCGKMCK_03849 4.16e-159 ywcC - - K - - - transcriptional regulator
LKCGKMCK_03851 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
LKCGKMCK_03852 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKCGKMCK_03853 1.08e-145 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
LKCGKMCK_03854 3.23e-310 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
LKCGKMCK_03855 6.21e-249 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
LKCGKMCK_03856 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
LKCGKMCK_03857 7.69e-150 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LKCGKMCK_03858 3.25e-185 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LKCGKMCK_03859 2.7e-203 ywbI - - K - - - Transcriptional regulator
LKCGKMCK_03860 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LKCGKMCK_03861 1.21e-143 ywbG - - M - - - effector of murein hydrolase
LKCGKMCK_03862 1.29e-280 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
LKCGKMCK_03863 1.32e-39 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
LKCGKMCK_03864 1.3e-283 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
LKCGKMCK_03865 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
LKCGKMCK_03866 7.78e-165 ywbB - - S - - - Protein of unknown function (DUF2711)
LKCGKMCK_03867 9.36e-317 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKCGKMCK_03868 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LKCGKMCK_03869 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKCGKMCK_03870 9.07e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
LKCGKMCK_03871 6.53e-217 gspA - - M - - - General stress
LKCGKMCK_03872 3.96e-164 ywaF - - S - - - Integral membrane protein
LKCGKMCK_03873 2.15e-115 ywaE - - K - - - Transcriptional regulator
LKCGKMCK_03874 2.7e-298 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LKCGKMCK_03875 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
LKCGKMCK_03876 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
LKCGKMCK_03877 5.1e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
LKCGKMCK_03878 1.27e-20 - - - S - - - D-Ala-teichoic acid biosynthesis protein
LKCGKMCK_03879 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKCGKMCK_03880 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
LKCGKMCK_03881 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKCGKMCK_03882 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LKCGKMCK_03883 2.91e-178 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LKCGKMCK_03884 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LKCGKMCK_03885 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LKCGKMCK_03886 1.58e-50 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKCGKMCK_03887 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKCGKMCK_03888 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
LKCGKMCK_03889 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
LKCGKMCK_03890 8.94e-28 yxzF - - - - - - -
LKCGKMCK_03891 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
LKCGKMCK_03892 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LKCGKMCK_03893 4.48e-277 yxlH - - EGP - - - Major Facilitator Superfamily
LKCGKMCK_03894 3.96e-179 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LKCGKMCK_03895 2.09e-213 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_03896 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
LKCGKMCK_03897 1.75e-43 - - - - - - - -
LKCGKMCK_03898 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
LKCGKMCK_03899 9.06e-125 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LKCGKMCK_03900 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
LKCGKMCK_03901 2.01e-206 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LKCGKMCK_03902 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
LKCGKMCK_03903 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
LKCGKMCK_03904 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
LKCGKMCK_03905 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
LKCGKMCK_03906 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
LKCGKMCK_03907 0.0 - - - O - - - Peptidase family M48
LKCGKMCK_03909 1.58e-200 yxkH - - G - - - Polysaccharide deacetylase
LKCGKMCK_03910 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKCGKMCK_03911 1.16e-211 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
LKCGKMCK_03912 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LKCGKMCK_03913 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LKCGKMCK_03914 1.66e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
LKCGKMCK_03915 2.11e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LKCGKMCK_03916 2.01e-123 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
LKCGKMCK_03917 1.53e-213 - - - K - - - LysR substrate binding domain
LKCGKMCK_03918 5.63e-102 - - - S - - - Protein of unknown function (DUF1453)
LKCGKMCK_03919 7.13e-261 - - - T - - - Signal transduction histidine kinase
LKCGKMCK_03920 5.66e-150 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
LKCGKMCK_03921 7.76e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LKCGKMCK_03924 2.57e-114 yxjI - - S - - - LURP-one-related
LKCGKMCK_03925 7.74e-280 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
LKCGKMCK_03926 9.77e-279 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
LKCGKMCK_03927 5.83e-176 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LKCGKMCK_03928 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LKCGKMCK_03929 4.65e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LKCGKMCK_03930 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
LKCGKMCK_03931 4.55e-206 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
LKCGKMCK_03932 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LKCGKMCK_03933 2.96e-29 - - - T - - - Domain of unknown function (DUF4163)
LKCGKMCK_03934 9.65e-65 yxiS - - - - - - -
LKCGKMCK_03935 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LKCGKMCK_03936 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LKCGKMCK_03937 2.62e-185 bglS - - M - - - licheninase activity
LKCGKMCK_03938 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
LKCGKMCK_03939 2.75e-145 - - - - - - - -
LKCGKMCK_03940 3.97e-294 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
LKCGKMCK_03941 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
LKCGKMCK_03942 3.28e-279 - - - E - - - GDSL-like Lipase/Acylhydrolase
LKCGKMCK_03945 5.53e-65 yxiJ - - S - - - YxiJ-like protein
LKCGKMCK_03946 3.79e-125 yxiI - - S - - - Protein of unknown function (DUF2716)
LKCGKMCK_03947 6.22e-107 - - - - - - - -
LKCGKMCK_03948 1.2e-57 - - - - - - - -
LKCGKMCK_03949 8.76e-99 yxiG - - - - - - -
LKCGKMCK_03950 1.12e-82 - - - - - - - -
LKCGKMCK_03951 3.69e-111 - - - - - - - -
LKCGKMCK_03952 1.09e-94 yxxG - - - - - - -
LKCGKMCK_03953 0.0 wapA - - M - - - COG3209 Rhs family protein
LKCGKMCK_03954 1.17e-216 yxxF - - EG - - - EamA-like transporter family
LKCGKMCK_03955 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
LKCGKMCK_03956 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LKCGKMCK_03957 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKCGKMCK_03958 1.33e-67 - - - - - - - -
LKCGKMCK_03959 9.25e-103 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
LKCGKMCK_03960 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
LKCGKMCK_03961 2.3e-53 yxiC - - S - - - Family of unknown function (DUF5344)
LKCGKMCK_03962 1.88e-37 - - - S - - - Domain of unknown function (DUF5082)
LKCGKMCK_03963 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
LKCGKMCK_03964 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
LKCGKMCK_03965 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
LKCGKMCK_03966 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LKCGKMCK_03967 2.44e-303 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
LKCGKMCK_03968 4.15e-232 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
LKCGKMCK_03969 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LKCGKMCK_03970 4.9e-300 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
LKCGKMCK_03971 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LKCGKMCK_03972 1.44e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LKCGKMCK_03973 4.26e-222 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LKCGKMCK_03974 9.11e-198 - - - S - - - Domain of Unknown Function (DUF1206)
LKCGKMCK_03975 4.86e-259 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
LKCGKMCK_03976 0.0 yxeQ - - S - - - MmgE/PrpD family
LKCGKMCK_03977 5.21e-275 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
LKCGKMCK_03978 1.67e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_03979 1.81e-149 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LKCGKMCK_03980 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LKCGKMCK_03981 1.54e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKCGKMCK_03982 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKCGKMCK_03984 2.17e-243 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
LKCGKMCK_03985 1.4e-194 yxeH - - S - - - hydrolases of the HAD superfamily
LKCGKMCK_03988 7.32e-42 yxeE - - - - - - -
LKCGKMCK_03989 2.66e-28 yxeD - - - - - - -
LKCGKMCK_03990 6.79e-91 - - - - - - - -
LKCGKMCK_03991 9.01e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LKCGKMCK_03992 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
LKCGKMCK_03993 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LKCGKMCK_03994 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LKCGKMCK_03995 4e-233 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKCGKMCK_03996 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKCGKMCK_03997 2.43e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LKCGKMCK_03998 9.32e-188 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
LKCGKMCK_03999 1.87e-213 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
LKCGKMCK_04000 1.55e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LKCGKMCK_04001 1.46e-298 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
LKCGKMCK_04002 4.27e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LKCGKMCK_04003 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LKCGKMCK_04004 2.13e-228 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LKCGKMCK_04005 1.46e-201 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LKCGKMCK_04006 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LKCGKMCK_04007 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LKCGKMCK_04008 1.74e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
LKCGKMCK_04010 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
LKCGKMCK_04011 1.77e-314 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LKCGKMCK_04012 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
LKCGKMCK_04014 4.33e-195 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LKCGKMCK_04015 8.57e-217 yxbF - - K - - - Bacterial regulatory proteins, tetR family
LKCGKMCK_04016 2.51e-35 yxbF - - K - - - Bacterial regulatory proteins, tetR family
LKCGKMCK_04017 1.21e-315 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LKCGKMCK_04018 6.59e-111 yxbD 3.2.2.20 - K ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Acetyltransferase (GNAT) domain
LKCGKMCK_04019 1.16e-239 - - - S - - - A domain family that is part of the cupin metalloenzyme superfamily.
LKCGKMCK_04020 1.29e-177 yxbB - - Q - - - Met-10+ like-protein
LKCGKMCK_04021 3.65e-59 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
LKCGKMCK_04022 8.99e-114 yxnB - - - - - - -
LKCGKMCK_04023 0.0 - 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LKCGKMCK_04024 1.8e-271 yxaM - - U - - - MFS_1 like family
LKCGKMCK_04025 2.63e-137 yxaL - - S - - - PQQ-like domain
LKCGKMCK_04026 1.43e-85 - - - S - - - Family of unknown function (DUF5391)
LKCGKMCK_04027 2.83e-99 yxaI - - S - - - membrane protein domain
LKCGKMCK_04028 2.88e-290 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
LKCGKMCK_04029 9.33e-254 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
LKCGKMCK_04030 9.61e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
LKCGKMCK_04031 4.48e-257 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LKCGKMCK_04032 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKCGKMCK_04033 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
LKCGKMCK_04034 2.19e-153 yxaC - - M - - - effector of murein hydrolase
LKCGKMCK_04035 1.79e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
LKCGKMCK_04036 2.54e-267 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
LKCGKMCK_04037 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
LKCGKMCK_04038 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
LKCGKMCK_04039 2.05e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
LKCGKMCK_04040 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LKCGKMCK_04041 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
LKCGKMCK_04042 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
LKCGKMCK_04043 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LKCGKMCK_04044 1.2e-23 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKCGKMCK_04045 6.34e-165 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
LKCGKMCK_04046 1.44e-24 - - - - - - - -
LKCGKMCK_04047 4.04e-154 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LKCGKMCK_04048 5.06e-144 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LKCGKMCK_04049 1.55e-173 - - - O ko:K16922 - ko00000,ko01002 Peptidase M50
LKCGKMCK_04050 1.35e-237 - - - S - - - Radical SAM superfamily
LKCGKMCK_04051 1.99e-17 - - - - - - - -
LKCGKMCK_04052 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
LKCGKMCK_04053 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
LKCGKMCK_04054 7.17e-86 - - - - - - - -
LKCGKMCK_04055 0.0 - - - S - - - Calcineurin-like phosphoesterase
LKCGKMCK_04056 1.23e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LKCGKMCK_04058 1.25e-93 - - - - - - - -
LKCGKMCK_04059 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LKCGKMCK_04061 1.7e-45 yycQ - - S - - - Protein of unknown function (DUF2651)
LKCGKMCK_04062 1.77e-281 yycP - - - - - - -
LKCGKMCK_04063 1.68e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LKCGKMCK_04064 3.84e-113 yycN - - K - - - Acetyltransferase
LKCGKMCK_04065 3.03e-239 - - - S - - - aspartate phosphatase
LKCGKMCK_04067 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
LKCGKMCK_04068 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LKCGKMCK_04069 1.5e-296 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
LKCGKMCK_04070 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LKCGKMCK_04071 2.42e-281 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKCGKMCK_04072 4.01e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LKCGKMCK_04073 1.2e-200 yycI - - S - - - protein conserved in bacteria
LKCGKMCK_04074 0.0 yycH - - S - - - protein conserved in bacteria
LKCGKMCK_04075 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKCGKMCK_04076 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKCGKMCK_04081 6.38e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LKCGKMCK_04082 1.19e-101 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKCGKMCK_04083 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LKCGKMCK_04084 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
LKCGKMCK_04086 1.89e-22 yycC - - K - - - YycC-like protein
LKCGKMCK_04087 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
LKCGKMCK_04088 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LKCGKMCK_04089 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
LKCGKMCK_04090 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
LKCGKMCK_04091 5.23e-205 yybS - - S - - - membrane
LKCGKMCK_04093 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
LKCGKMCK_04094 6.68e-90 yybR - - K - - - Transcriptional regulator
LKCGKMCK_04095 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
LKCGKMCK_04096 2.34e-92 - - - - - - - -
LKCGKMCK_04098 6.8e-308 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LKCGKMCK_04099 3.44e-22 - - - - - - - -
LKCGKMCK_04100 1.61e-102 yybN - - S - - - Protein of unknown function (DUF2712)
LKCGKMCK_04101 3.78e-169 - - - - - - - -
LKCGKMCK_04102 5.36e-157 - - - - - - - -
LKCGKMCK_04103 2.34e-163 - - - S - - - Protein of unknown function (DUF2705)
LKCGKMCK_04104 1.14e-149 yybJ - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LKCGKMCK_04105 4.35e-194 - - - - - - - -
LKCGKMCK_04106 3.02e-88 - - - S - - - SnoaL-like domain
LKCGKMCK_04107 1.46e-164 yybG - - S - - - Pentapeptide repeat-containing protein
LKCGKMCK_04108 3.31e-281 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LKCGKMCK_04109 1.36e-212 yybE - - K - - - Transcriptional regulator
LKCGKMCK_04110 7.91e-104 yjcF - - S - - - Acetyltransferase (GNAT) domain
LKCGKMCK_04111 1.27e-99 yybC - - - - - - -
LKCGKMCK_04112 5.29e-165 - - - S - - - Metallo-beta-lactamase superfamily
LKCGKMCK_04113 4.54e-100 yybA - - K - - - transcriptional
LKCGKMCK_04114 2.45e-103 yjcF - - S - - - Acetyltransferase (GNAT) domain
LKCGKMCK_04115 8.73e-132 yyaS - - S ko:K07149 - ko00000 Membrane
LKCGKMCK_04116 4.03e-130 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
LKCGKMCK_04117 1.09e-87 - - - S - - - YjbR
LKCGKMCK_04118 2.2e-139 yyaP - - H - - - RibD C-terminal domain
LKCGKMCK_04119 0.0 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
LKCGKMCK_04120 1.46e-58 yyaL - - O ko:K06888 - ko00000 Highly conserved protein containing a thioredoxin domain
LKCGKMCK_04121 1.34e-88 - - - K - - - MerR HTH family regulatory protein
LKCGKMCK_04122 1.99e-207 - - - EG - - - EamA-like transporter family
LKCGKMCK_04123 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
LKCGKMCK_04124 8.91e-217 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
LKCGKMCK_04125 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
LKCGKMCK_04126 1.14e-130 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
LKCGKMCK_04127 7.2e-90 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKCGKMCK_04128 3.03e-230 ccpB - - K - - - Transcriptional regulator
LKCGKMCK_04129 2.07e-187 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LKCGKMCK_04130 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LKCGKMCK_04131 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LKCGKMCK_04132 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
LKCGKMCK_04133 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LKCGKMCK_04134 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LKCGKMCK_04135 7.41e-45 yyzM - - S - - - protein conserved in bacteria
LKCGKMCK_04136 5.34e-227 yyaD - - S - - - Membrane
LKCGKMCK_04137 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
LKCGKMCK_04138 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LKCGKMCK_04139 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
LKCGKMCK_04140 1.13e-98 - - - S - - - Bacterial PH domain
LKCGKMCK_04141 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LKCGKMCK_04142 8.68e-169 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LKCGKMCK_04143 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LKCGKMCK_04144 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LKCGKMCK_04145 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
LKCGKMCK_04146 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LKCGKMCK_04147 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LKCGKMCK_04150 5.95e-71 - - - - ko:K18640 - ko00000,ko04812 -
LKCGKMCK_04168 3.05e-67 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LKCGKMCK_04169 5.04e-128 dcm 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
LKCGKMCK_04173 2.59e-16 - - - L - - - Psort location Cytoplasmic, score 8.96
LKCGKMCK_04174 1.28e-32 - - - - - - - -
LKCGKMCK_04175 1.43e-123 - - - S ko:K06361,ko:K06365 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
LKCGKMCK_04177 0.000876 - - - M - - - PFAM L,D-transpeptidase catalytic domain
LKCGKMCK_04179 1.26e-97 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LKCGKMCK_04181 1.43e-29 - - - V - - - VanZ like family
LKCGKMCK_04183 5.37e-35 - - - - - - - -
LKCGKMCK_04185 3.9e-20 - - - S - - - YolD-like protein
LKCGKMCK_04188 1.22e-167 - - - L - - - Phage integrase, N-terminal SAM-like domain
LKCGKMCK_04191 1.71e-167 - 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LKCGKMCK_04194 1.47e-17 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LKCGKMCK_04195 4.11e-60 - 3.1.31.1 - L ko:K01174 - ko00000,ko01000 Staphylococcal nuclease homologues
LKCGKMCK_04199 6.89e-05 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LKCGKMCK_04205 9.36e-06 - - - D ko:K04562 - ko00000,ko02035 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family
LKCGKMCK_04206 2.64e-30 cpaF1 - - U ko:K02283 - ko00000,ko02035,ko02044 Type II/IV secretion system protein
LKCGKMCK_04214 2.89e-94 - - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Transglycosylase SLT domain

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)