ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
CFDGDPAD_00017 1.29e-184 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
CFDGDPAD_00018 1.58e-36 - - - - - - - -
CFDGDPAD_00019 4.02e-172 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
CFDGDPAD_00021 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CFDGDPAD_00022 0.0 ygaK - - C - - - Berberine and berberine like
CFDGDPAD_00024 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
CFDGDPAD_00025 3.01e-177 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
CFDGDPAD_00026 1.7e-217 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
CFDGDPAD_00027 4.82e-189 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
CFDGDPAD_00028 9.35e-276 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
CFDGDPAD_00030 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFDGDPAD_00031 2.79e-102 ygaO - - - - - - -
CFDGDPAD_00032 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_00034 1.92e-147 yhzB - - S - - - B3/4 domain
CFDGDPAD_00035 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFDGDPAD_00036 9.27e-224 yhbB - - S - - - Putative amidase domain
CFDGDPAD_00037 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CFDGDPAD_00038 3.97e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
CFDGDPAD_00039 1.32e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
CFDGDPAD_00040 3.32e-102 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
CFDGDPAD_00041 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
CFDGDPAD_00042 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
CFDGDPAD_00043 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
CFDGDPAD_00044 3.8e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
CFDGDPAD_00045 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
CFDGDPAD_00046 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
CFDGDPAD_00047 3.24e-58 yhcC - - - - - - -
CFDGDPAD_00048 2.92e-69 - - - - - - - -
CFDGDPAD_00049 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_00050 3.38e-158 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_00051 5.31e-212 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_00052 3.45e-212 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CFDGDPAD_00053 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
CFDGDPAD_00054 4.31e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
CFDGDPAD_00055 1.17e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
CFDGDPAD_00056 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CFDGDPAD_00057 2.51e-74 yhcM - - - - - - -
CFDGDPAD_00058 2.69e-111 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CFDGDPAD_00059 3.96e-227 yhcP - - - - - - -
CFDGDPAD_00060 1.68e-146 yhcQ - - M - - - Spore coat protein
CFDGDPAD_00061 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
CFDGDPAD_00062 3.9e-138 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
CFDGDPAD_00063 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
CFDGDPAD_00064 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
CFDGDPAD_00065 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
CFDGDPAD_00066 2.92e-153 yhcW - - S ko:K07025 - ko00000 hydrolase
CFDGDPAD_00067 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CFDGDPAD_00068 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFDGDPAD_00069 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CFDGDPAD_00070 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
CFDGDPAD_00071 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CFDGDPAD_00072 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CFDGDPAD_00073 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
CFDGDPAD_00074 3.11e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
CFDGDPAD_00075 3.83e-144 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFDGDPAD_00076 1.63e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
CFDGDPAD_00077 1.65e-51 yhdB - - S - - - YhdB-like protein
CFDGDPAD_00078 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
CFDGDPAD_00079 1.14e-273 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
CFDGDPAD_00080 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
CFDGDPAD_00081 1.51e-306 ygxB - - M - - - Conserved TM helix
CFDGDPAD_00082 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
CFDGDPAD_00083 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
CFDGDPAD_00084 5.92e-203 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
CFDGDPAD_00085 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_00086 9.13e-262 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
CFDGDPAD_00087 1.58e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDGDPAD_00088 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
CFDGDPAD_00089 4.29e-310 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CFDGDPAD_00090 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CFDGDPAD_00091 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFDGDPAD_00092 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
CFDGDPAD_00093 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
CFDGDPAD_00094 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CFDGDPAD_00095 6.74e-244 yhdN - - C - - - Aldo keto reductase
CFDGDPAD_00096 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CFDGDPAD_00097 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
CFDGDPAD_00098 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
CFDGDPAD_00099 9.86e-282 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
CFDGDPAD_00100 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
CFDGDPAD_00101 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFDGDPAD_00102 3.38e-86 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CFDGDPAD_00103 1.56e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
CFDGDPAD_00104 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
CFDGDPAD_00105 1.06e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
CFDGDPAD_00106 1.98e-178 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
CFDGDPAD_00107 3.54e-194 nodB1 - - G - - - deacetylase
CFDGDPAD_00108 6.65e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
CFDGDPAD_00109 3.61e-303 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
CFDGDPAD_00110 1.29e-107 nhaX - - T - - - Belongs to the universal stress protein A family
CFDGDPAD_00111 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
CFDGDPAD_00112 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
CFDGDPAD_00113 1.11e-141 yheG - - GM - - - NAD(P)H-binding
CFDGDPAD_00114 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
CFDGDPAD_00115 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
CFDGDPAD_00116 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
CFDGDPAD_00117 3.94e-275 yheC - - HJ - - - YheC/D like ATP-grasp
CFDGDPAD_00118 4.16e-259 yheB - - S - - - Belongs to the UPF0754 family
CFDGDPAD_00119 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
CFDGDPAD_00120 5.27e-261 yhaZ - - L - - - DNA alkylation repair enzyme
CFDGDPAD_00121 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
CFDGDPAD_00122 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
CFDGDPAD_00123 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
CFDGDPAD_00124 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
CFDGDPAD_00126 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
CFDGDPAD_00127 2.29e-36 - - - S - - - YhzD-like protein
CFDGDPAD_00128 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_00129 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
CFDGDPAD_00130 6.11e-297 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
CFDGDPAD_00131 0.0 yhaN - - L - - - AAA domain
CFDGDPAD_00132 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
CFDGDPAD_00133 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
CFDGDPAD_00134 4.04e-162 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CFDGDPAD_00135 1.4e-116 yhaK - - S - - - Putative zincin peptidase
CFDGDPAD_00136 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
CFDGDPAD_00137 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
CFDGDPAD_00138 3.89e-54 yhaH - - S - - - YtxH-like protein
CFDGDPAD_00139 9.66e-30 - - - - - - - -
CFDGDPAD_00140 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
CFDGDPAD_00141 2.61e-260 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CFDGDPAD_00142 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
CFDGDPAD_00143 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
CFDGDPAD_00144 2.01e-268 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
CFDGDPAD_00145 2.89e-161 ecsC - - S - - - EcsC protein family
CFDGDPAD_00146 1.27e-290 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CFDGDPAD_00147 3.29e-313 yhfA - - C - - - membrane
CFDGDPAD_00148 2.18e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
CFDGDPAD_00149 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
CFDGDPAD_00150 1.29e-259 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CFDGDPAD_00151 3.41e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
CFDGDPAD_00152 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CFDGDPAD_00153 1e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_00154 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
CFDGDPAD_00155 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFDGDPAD_00156 9.33e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
CFDGDPAD_00157 1.55e-252 yhfE - - G - - - peptidase M42
CFDGDPAD_00158 1.53e-93 - - - S - - - ASCH
CFDGDPAD_00159 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CFDGDPAD_00160 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
CFDGDPAD_00161 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
CFDGDPAD_00162 7.43e-144 yhfK - - GM - - - NmrA-like family
CFDGDPAD_00163 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
CFDGDPAD_00164 2.78e-85 yhfM - - - - - - -
CFDGDPAD_00165 1.12e-306 yhfN - - O - - - Peptidase M48
CFDGDPAD_00166 1.7e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
CFDGDPAD_00167 6.23e-102 - - - K - - - acetyltransferase
CFDGDPAD_00168 1.39e-231 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
CFDGDPAD_00169 2.77e-223 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
CFDGDPAD_00170 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
CFDGDPAD_00171 2.87e-248 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
CFDGDPAD_00172 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
CFDGDPAD_00173 4.21e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
CFDGDPAD_00174 5.29e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
CFDGDPAD_00175 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
CFDGDPAD_00176 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDGDPAD_00177 9.84e-45 yhzC - - S - - - IDEAL
CFDGDPAD_00178 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
CFDGDPAD_00179 2.55e-216 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
CFDGDPAD_00180 4.82e-55 yhjA - - S - - - Excalibur calcium-binding domain
CFDGDPAD_00181 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFDGDPAD_00182 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
CFDGDPAD_00183 2.12e-77 yhjD - - - - - - -
CFDGDPAD_00184 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
CFDGDPAD_00185 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
CFDGDPAD_00186 0.0 yhjG - - CH - - - FAD binding domain
CFDGDPAD_00187 4.68e-121 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
CFDGDPAD_00188 2.11e-271 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
CFDGDPAD_00189 1.14e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
CFDGDPAD_00190 5.31e-205 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
CFDGDPAD_00191 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
CFDGDPAD_00192 2.52e-238 yhjM - - K - - - Transcriptional regulator
CFDGDPAD_00193 1.19e-257 yhjN - - S ko:K07120 - ko00000 membrane
CFDGDPAD_00194 4.74e-268 - - - EGP - - - Transmembrane secretion effector
CFDGDPAD_00195 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
CFDGDPAD_00196 9.3e-102 yhjR - - S - - - Rubrerythrin
CFDGDPAD_00197 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
CFDGDPAD_00198 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
CFDGDPAD_00199 1.4e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CFDGDPAD_00200 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
CFDGDPAD_00201 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
CFDGDPAD_00202 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
CFDGDPAD_00203 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
CFDGDPAD_00204 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
CFDGDPAD_00205 2.88e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
CFDGDPAD_00206 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
CFDGDPAD_00207 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
CFDGDPAD_00208 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
CFDGDPAD_00209 7.66e-222 cotH - - M ko:K06330 - ko00000 Spore Coat
CFDGDPAD_00210 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
CFDGDPAD_00211 2.05e-74 yisL - - S - - - UPF0344 protein
CFDGDPAD_00212 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
CFDGDPAD_00213 3.68e-132 yisN - - S - - - Protein of unknown function (DUF2777)
CFDGDPAD_00214 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
CFDGDPAD_00215 1.07e-114 yizA - - S - - - Damage-inducible protein DinB
CFDGDPAD_00216 3.11e-189 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
CFDGDPAD_00217 1.01e-310 yisQ - - V - - - Mate efflux family protein
CFDGDPAD_00218 4.04e-207 yisR - - K - - - Transcriptional regulator
CFDGDPAD_00219 2.14e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
CFDGDPAD_00221 8.22e-246 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
CFDGDPAD_00222 5.98e-121 yisT - - S - - - DinB family
CFDGDPAD_00223 1.49e-137 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
CFDGDPAD_00224 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CFDGDPAD_00225 4.25e-65 yisX - - S - - - Pentapeptide repeats (9 copies)
CFDGDPAD_00226 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CFDGDPAD_00227 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
CFDGDPAD_00228 1.6e-294 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
CFDGDPAD_00229 1.3e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
CFDGDPAD_00230 9.04e-161 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
CFDGDPAD_00231 1.75e-179 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
CFDGDPAD_00232 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
CFDGDPAD_00233 2.5e-282 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
CFDGDPAD_00234 1.01e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CFDGDPAD_00235 3.69e-196 yitH - - K - - - Acetyltransferase (GNAT) domain
CFDGDPAD_00236 1.46e-91 - - - S - - - Acetyltransferase (GNAT) domain
CFDGDPAD_00237 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
CFDGDPAD_00238 4.29e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
CFDGDPAD_00239 2.75e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
CFDGDPAD_00240 4.16e-122 - - - - - - - -
CFDGDPAD_00241 1.17e-217 - - - - - - - -
CFDGDPAD_00242 5.46e-126 - - - S - - - Sporulation delaying protein SdpA
CFDGDPAD_00243 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
CFDGDPAD_00244 4.49e-122 - - - - - - - -
CFDGDPAD_00245 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
CFDGDPAD_00246 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
CFDGDPAD_00247 9.13e-202 yitS - - S - - - protein conserved in bacteria
CFDGDPAD_00248 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
CFDGDPAD_00249 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
CFDGDPAD_00250 4.11e-25 - - - S - - - Protein of unknown function (DUF3813)
CFDGDPAD_00251 1.92e-08 - - - - - - - -
CFDGDPAD_00252 4.35e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
CFDGDPAD_00253 2.92e-184 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
CFDGDPAD_00254 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
CFDGDPAD_00255 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
CFDGDPAD_00256 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
CFDGDPAD_00257 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
CFDGDPAD_00258 3.52e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CFDGDPAD_00259 8.64e-294 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFDGDPAD_00260 3.64e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
CFDGDPAD_00261 1.55e-274 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
CFDGDPAD_00262 2.33e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
CFDGDPAD_00263 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
CFDGDPAD_00264 1.05e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CFDGDPAD_00265 2.51e-39 yjzC - - S - - - YjzC-like protein
CFDGDPAD_00266 1.53e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
CFDGDPAD_00267 2.82e-181 yjaU - - I - - - carboxylic ester hydrolase activity
CFDGDPAD_00268 4.11e-129 yjaV - - - - - - -
CFDGDPAD_00269 3.7e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
CFDGDPAD_00270 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
CFDGDPAD_00271 2.67e-38 yjzB - - - - - - -
CFDGDPAD_00272 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFDGDPAD_00273 1.25e-301 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CFDGDPAD_00274 9.48e-193 yjaZ - - O - - - Zn-dependent protease
CFDGDPAD_00275 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CFDGDPAD_00276 4.01e-235 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CFDGDPAD_00277 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
CFDGDPAD_00278 6.73e-216 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFDGDPAD_00279 3.49e-196 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFDGDPAD_00280 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
CFDGDPAD_00281 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
CFDGDPAD_00282 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
CFDGDPAD_00283 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFDGDPAD_00284 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFDGDPAD_00285 3.22e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CFDGDPAD_00286 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CFDGDPAD_00287 2.26e-258 yjbB - - EGP - - - Major Facilitator Superfamily
CFDGDPAD_00288 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFDGDPAD_00289 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CFDGDPAD_00290 2.03e-143 yjbE - - P - - - Integral membrane protein TerC family
CFDGDPAD_00291 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CFDGDPAD_00292 4.91e-279 coiA - - S ko:K06198 - ko00000 Competence protein
CFDGDPAD_00293 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
CFDGDPAD_00294 2.68e-28 - - - - - - - -
CFDGDPAD_00296 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
CFDGDPAD_00297 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
CFDGDPAD_00298 3.42e-127 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CFDGDPAD_00299 2.98e-129 yjbK - - S - - - protein conserved in bacteria
CFDGDPAD_00300 5.35e-81 yjbL - - S - - - Belongs to the UPF0738 family
CFDGDPAD_00301 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
CFDGDPAD_00302 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFDGDPAD_00303 9.01e-204 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
CFDGDPAD_00304 2.71e-179 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
CFDGDPAD_00305 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CFDGDPAD_00306 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CFDGDPAD_00307 2.71e-137 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
CFDGDPAD_00308 1e-271 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
CFDGDPAD_00309 2.18e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
CFDGDPAD_00310 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
CFDGDPAD_00311 2.52e-237 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CFDGDPAD_00312 4.85e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
CFDGDPAD_00313 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
CFDGDPAD_00314 2.56e-104 yjbX - - S - - - Spore coat protein
CFDGDPAD_00315 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
CFDGDPAD_00316 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
CFDGDPAD_00317 1.23e-95 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
CFDGDPAD_00318 9.3e-32 cotW - - - ko:K06341 - ko00000 -
CFDGDPAD_00319 6.69e-66 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
CFDGDPAD_00320 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
CFDGDPAD_00323 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
CFDGDPAD_00324 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
CFDGDPAD_00325 6.31e-51 - - - - - - - -
CFDGDPAD_00326 1.1e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFDGDPAD_00327 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
CFDGDPAD_00328 1.91e-177 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
CFDGDPAD_00329 7.71e-271 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
CFDGDPAD_00330 1.84e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
CFDGDPAD_00331 7.14e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
CFDGDPAD_00332 3.08e-259 yjcL - - S - - - Protein of unknown function (DUF819)
CFDGDPAD_00334 1.56e-11 int7 - - L - - - Belongs to the 'phage' integrase family
CFDGDPAD_00335 2e-64 - - - - - - - -
CFDGDPAD_00336 8.54e-239 - - - S - - - Bacterial EndoU nuclease
CFDGDPAD_00337 1.34e-23 - - - M - - - nucleic acid phosphodiester bond hydrolysis
CFDGDPAD_00340 3.46e-36 - - - K - - - Cro/C1-type HTH DNA-binding domain
CFDGDPAD_00342 6.31e-62 - - - - - - - -
CFDGDPAD_00343 1.51e-309 - - - I - - - Pfam Lipase (class 3)
CFDGDPAD_00346 1.5e-89 - - - - - - - -
CFDGDPAD_00348 2.55e-228 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
CFDGDPAD_00349 5.19e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
CFDGDPAD_00350 2.81e-180 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
CFDGDPAD_00351 0.000759 - - - - - - - -
CFDGDPAD_00352 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
CFDGDPAD_00353 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CFDGDPAD_00354 4.89e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
CFDGDPAD_00355 4.79e-78 yjdF3 - - S - - - Protein of unknown function (DUF2992)
CFDGDPAD_00356 1.47e-116 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
CFDGDPAD_00358 1.38e-103 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFDGDPAD_00359 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
CFDGDPAD_00360 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
CFDGDPAD_00361 5.31e-224 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CFDGDPAD_00363 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
CFDGDPAD_00364 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
CFDGDPAD_00365 1.13e-29 yjfB - - S - - - Putative motility protein
CFDGDPAD_00366 3.48e-214 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
CFDGDPAD_00367 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
CFDGDPAD_00368 5.79e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
CFDGDPAD_00369 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
CFDGDPAD_00370 6.51e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
CFDGDPAD_00372 3.17e-148 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
CFDGDPAD_00374 1.25e-281 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
CFDGDPAD_00375 5.89e-278 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CFDGDPAD_00376 1.11e-41 - - - - - - - -
CFDGDPAD_00377 1.13e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
CFDGDPAD_00378 3.68e-155 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
CFDGDPAD_00379 2.3e-174 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
CFDGDPAD_00380 1.27e-224 yjlA - - EG - - - Putative multidrug resistance efflux transporter
CFDGDPAD_00381 2.46e-118 yjlB - - S - - - Cupin domain
CFDGDPAD_00382 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
CFDGDPAD_00383 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
CFDGDPAD_00384 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
CFDGDPAD_00385 1.51e-314 - - - G ko:K03292 - ko00000 symporter YjmB
CFDGDPAD_00386 7.79e-237 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
CFDGDPAD_00387 8.86e-244 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
CFDGDPAD_00388 1.94e-273 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
CFDGDPAD_00389 2.71e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDGDPAD_00390 2.27e-288 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
CFDGDPAD_00391 4.02e-237 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
CFDGDPAD_00392 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
CFDGDPAD_00393 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
CFDGDPAD_00394 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
CFDGDPAD_00395 4.68e-104 yjoA - - S - - - DinB family
CFDGDPAD_00396 5.59e-310 VCP - - O - - - AAA domain (dynein-related subfamily)
CFDGDPAD_00397 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
CFDGDPAD_00399 1.79e-55 - - - S - - - YCII-related domain
CFDGDPAD_00400 2.08e-215 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
CFDGDPAD_00401 1.35e-80 yjqA - - S - - - Bacterial PH domain
CFDGDPAD_00402 5.99e-143 yjqB - - S - - - Pfam:DUF867
CFDGDPAD_00403 1.85e-203 yjqC - - P ko:K07217 - ko00000 Catalase
CFDGDPAD_00404 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
CFDGDPAD_00405 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
CFDGDPAD_00407 4.36e-202 xkdB - - K - - - sequence-specific DNA binding
CFDGDPAD_00408 1.44e-150 xkdC - - L - - - Bacterial dnaA protein
CFDGDPAD_00412 2.72e-108 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
CFDGDPAD_00413 1.6e-177 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
CFDGDPAD_00414 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
CFDGDPAD_00415 0.0 yqbA - - S - - - portal protein
CFDGDPAD_00416 5.47e-174 xkdF3 - - L - - - Putative phage serine protease XkdF
CFDGDPAD_00417 7.89e-217 xkdG - - S - - - Phage capsid family
CFDGDPAD_00418 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
CFDGDPAD_00419 1.5e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
CFDGDPAD_00420 9.69e-114 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
CFDGDPAD_00421 2.87e-101 xkdJ - - - - - - -
CFDGDPAD_00422 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
CFDGDPAD_00423 6.01e-99 xkdM - - S - - - Phage tail tube protein
CFDGDPAD_00424 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
CFDGDPAD_00425 0.0 xkdO - - L - - - Transglycosylase SLT domain
CFDGDPAD_00426 8.57e-152 xkdP - - S - - - Lysin motif
CFDGDPAD_00427 4.67e-232 xkdQ - - G - - - NLP P60 protein
CFDGDPAD_00428 6.14e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
CFDGDPAD_00429 1.56e-89 xkdS - - S - - - Protein of unknown function (DUF2634)
CFDGDPAD_00430 3.09e-244 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
CFDGDPAD_00431 3.77e-133 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
CFDGDPAD_00432 1.81e-55 - - - - - - - -
CFDGDPAD_00433 0.0 - - - - - - - -
CFDGDPAD_00434 9.77e-71 xkdW - - S - - - XkdW protein
CFDGDPAD_00435 9.34e-33 xkdX - - - - - - -
CFDGDPAD_00436 1.51e-198 xepA - - - - - - -
CFDGDPAD_00437 7.71e-52 xhlA - - S - - - Haemolysin XhlA
CFDGDPAD_00438 8.12e-53 xhlB - - S - - - SPP1 phage holin
CFDGDPAD_00439 5.76e-212 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
CFDGDPAD_00440 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
CFDGDPAD_00441 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
CFDGDPAD_00442 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
CFDGDPAD_00443 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
CFDGDPAD_00444 7.7e-311 steT - - E ko:K03294 - ko00000 amino acid
CFDGDPAD_00445 2.31e-232 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
CFDGDPAD_00447 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CFDGDPAD_00448 1.34e-230 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
CFDGDPAD_00450 1.14e-282 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFDGDPAD_00451 2.25e-176 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
CFDGDPAD_00452 2.82e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
CFDGDPAD_00453 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFDGDPAD_00454 1.01e-222 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFDGDPAD_00455 2.23e-235 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CFDGDPAD_00456 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
CFDGDPAD_00457 1.59e-223 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
CFDGDPAD_00458 5.9e-258 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
CFDGDPAD_00459 5.11e-210 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CFDGDPAD_00460 4.88e-236 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CFDGDPAD_00461 1.34e-259 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
CFDGDPAD_00462 1.78e-205 ykgA - - E - - - Amidinotransferase
CFDGDPAD_00463 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
CFDGDPAD_00464 1.53e-288 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CFDGDPAD_00465 3.55e-14 - - - - - - - -
CFDGDPAD_00466 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
CFDGDPAD_00467 5.28e-127 ykkA - - S - - - Protein of unknown function (DUF664)
CFDGDPAD_00468 1.2e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CFDGDPAD_00469 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
CFDGDPAD_00470 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
CFDGDPAD_00471 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
CFDGDPAD_00472 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFDGDPAD_00473 1.6e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CFDGDPAD_00474 1.97e-92 ohrA - - O - - - Organic hydroperoxide resistance protein
CFDGDPAD_00475 1.42e-97 ohrR - - K - - - COG1846 Transcriptional regulators
CFDGDPAD_00476 1.35e-92 ohrB - - O - - - Organic hydroperoxide resistance protein
CFDGDPAD_00477 1.9e-113 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
CFDGDPAD_00478 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CFDGDPAD_00479 6.07e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
CFDGDPAD_00480 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CFDGDPAD_00481 2.11e-172 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
CFDGDPAD_00482 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_00483 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
CFDGDPAD_00484 2.44e-142 ykoF - - S - - - YKOF-related Family
CFDGDPAD_00485 1.5e-159 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDGDPAD_00486 2.46e-306 ykoH - - T - - - Histidine kinase
CFDGDPAD_00487 9.2e-144 ykoI - - S - - - Peptidase propeptide and YPEB domain
CFDGDPAD_00488 5.28e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
CFDGDPAD_00489 1.45e-08 - - - - - - - -
CFDGDPAD_00491 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
CFDGDPAD_00492 1.49e-70 tnrA - - K - - - transcriptional
CFDGDPAD_00493 3.3e-25 - - - - - - - -
CFDGDPAD_00494 2.51e-35 ykoL - - - - - - -
CFDGDPAD_00495 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
CFDGDPAD_00496 1.09e-277 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
CFDGDPAD_00497 2.9e-128 ykoP - - G - - - polysaccharide deacetylase
CFDGDPAD_00498 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
CFDGDPAD_00499 0.0 ykoS - - - - - - -
CFDGDPAD_00500 3.86e-237 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
CFDGDPAD_00501 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
CFDGDPAD_00502 5.1e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CFDGDPAD_00503 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
CFDGDPAD_00504 1.71e-143 ykoX - - S - - - membrane-associated protein
CFDGDPAD_00505 1.33e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
CFDGDPAD_00506 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFDGDPAD_00507 8.08e-213 rsgI - - S - - - Anti-sigma factor N-terminus
CFDGDPAD_00508 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
CFDGDPAD_00509 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
CFDGDPAD_00510 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
CFDGDPAD_00511 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
CFDGDPAD_00513 2.51e-28 ykzE - - - - - - -
CFDGDPAD_00514 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
CFDGDPAD_00515 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFDGDPAD_00516 7.91e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFDGDPAD_00518 1.55e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CFDGDPAD_00519 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CFDGDPAD_00520 6.67e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CFDGDPAD_00521 6.84e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
CFDGDPAD_00522 5.39e-292 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
CFDGDPAD_00523 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CFDGDPAD_00524 1.84e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
CFDGDPAD_00525 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CFDGDPAD_00526 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
CFDGDPAD_00528 5.84e-95 eag - - - - - - -
CFDGDPAD_00529 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
CFDGDPAD_00530 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
CFDGDPAD_00531 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
CFDGDPAD_00532 1.65e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
CFDGDPAD_00533 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
CFDGDPAD_00534 6.76e-227 ykvI - - S - - - membrane
CFDGDPAD_00535 1.11e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CFDGDPAD_00536 4.03e-104 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
CFDGDPAD_00537 3.56e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
CFDGDPAD_00538 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CFDGDPAD_00539 7.06e-80 - - - K - - - HxlR-like helix-turn-helix
CFDGDPAD_00540 1.09e-171 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
CFDGDPAD_00541 1.74e-271 - - - M - - - Glycosyl transferases group 1
CFDGDPAD_00542 7.56e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
CFDGDPAD_00543 2.48e-204 - - - G - - - Glycosyl hydrolases family 18
CFDGDPAD_00544 2.67e-62 ykvR - - S - - - Protein of unknown function (DUF3219)
CFDGDPAD_00545 5.43e-35 ykvS - - S - - - protein conserved in bacteria
CFDGDPAD_00546 2.6e-39 - - - - - - - -
CFDGDPAD_00547 3.7e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
CFDGDPAD_00548 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CFDGDPAD_00549 5.57e-115 stoA - - CO - - - thiol-disulfide
CFDGDPAD_00550 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
CFDGDPAD_00551 3.19e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
CFDGDPAD_00552 7.72e-229 ykvZ - - K - - - Transcriptional regulator
CFDGDPAD_00554 2.79e-167 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
CFDGDPAD_00555 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CFDGDPAD_00556 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
CFDGDPAD_00557 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFDGDPAD_00558 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_00559 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
CFDGDPAD_00560 4.37e-162 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFDGDPAD_00561 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CFDGDPAD_00562 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
CFDGDPAD_00563 8.88e-171 ykwD - - J - - - protein with SCP PR1 domains
CFDGDPAD_00564 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
CFDGDPAD_00565 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFDGDPAD_00566 1.46e-283 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
CFDGDPAD_00567 1.05e-22 - - - - - - - -
CFDGDPAD_00568 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
CFDGDPAD_00569 3.71e-110 ykyB - - S - - - YkyB-like protein
CFDGDPAD_00570 3.62e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
CFDGDPAD_00571 5.84e-115 ykuD - - S - - - protein conserved in bacteria
CFDGDPAD_00572 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
CFDGDPAD_00573 1.83e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDGDPAD_00574 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
CFDGDPAD_00575 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
CFDGDPAD_00576 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
CFDGDPAD_00577 7.83e-38 ykzF - - S - - - Antirepressor AbbA
CFDGDPAD_00578 5.15e-100 ykuL - - S - - - CBS domain
CFDGDPAD_00579 6.52e-216 ccpC - - K - - - Transcriptional regulator
CFDGDPAD_00580 1.44e-109 - - - C ko:K03839 - ko00000 Flavodoxin domain
CFDGDPAD_00581 2.58e-224 ykuO - - - - - - -
CFDGDPAD_00582 6.2e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
CFDGDPAD_00583 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CFDGDPAD_00584 1.88e-274 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CFDGDPAD_00585 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
CFDGDPAD_00586 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
CFDGDPAD_00587 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
CFDGDPAD_00588 2.86e-102 ykuV - - CO - - - thiol-disulfide
CFDGDPAD_00589 4.71e-122 rok - - K - - - Repressor of ComK
CFDGDPAD_00590 3.45e-200 yknT - - - ko:K06437 - ko00000 -
CFDGDPAD_00591 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
CFDGDPAD_00592 5.34e-245 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CFDGDPAD_00593 1.75e-312 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
CFDGDPAD_00594 3.44e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
CFDGDPAD_00595 3.83e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
CFDGDPAD_00596 6.92e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CFDGDPAD_00597 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
CFDGDPAD_00598 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
CFDGDPAD_00599 1.31e-150 yknW - - S - - - Yip1 domain
CFDGDPAD_00600 2.72e-232 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFDGDPAD_00601 8.67e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_00602 3.33e-266 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
CFDGDPAD_00603 8.65e-175 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_00604 6.74e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
CFDGDPAD_00605 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
CFDGDPAD_00606 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
CFDGDPAD_00607 5.43e-52 ykoA - - - - - - -
CFDGDPAD_00608 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CFDGDPAD_00609 2.86e-215 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFDGDPAD_00610 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
CFDGDPAD_00611 1.09e-18 - - - S - - - Uncharacterized protein YkpC
CFDGDPAD_00612 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
CFDGDPAD_00613 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
CFDGDPAD_00614 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
CFDGDPAD_00615 9.21e-208 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
CFDGDPAD_00616 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
CFDGDPAD_00617 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CFDGDPAD_00618 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CFDGDPAD_00619 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
CFDGDPAD_00620 2.03e-187 ykrA - - S - - - hydrolases of the HAD superfamily
CFDGDPAD_00621 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CFDGDPAD_00622 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
CFDGDPAD_00623 8.67e-138 ykyA - - L - - - Putative cell-wall binding lipoprotein
CFDGDPAD_00624 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CFDGDPAD_00625 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CFDGDPAD_00626 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CFDGDPAD_00627 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CFDGDPAD_00628 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
CFDGDPAD_00629 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
CFDGDPAD_00630 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
CFDGDPAD_00631 1.3e-152 yktB - - S - - - Belongs to the UPF0637 family
CFDGDPAD_00632 4.48e-35 ykzI - - - - - - -
CFDGDPAD_00633 3.86e-194 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
CFDGDPAD_00634 1.48e-100 ykzC - - S - - - Acetyltransferase (GNAT) family
CFDGDPAD_00635 7.08e-221 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CFDGDPAD_00636 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
CFDGDPAD_00637 0.0 ylaA - - - - - - -
CFDGDPAD_00638 1.44e-56 ylaB - - - - - - -
CFDGDPAD_00639 5.27e-117 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CFDGDPAD_00641 5.7e-56 ylaE - - - - - - -
CFDGDPAD_00642 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
CFDGDPAD_00643 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
CFDGDPAD_00644 5.14e-62 ylaH - - S - - - YlaH-like protein
CFDGDPAD_00645 8.92e-44 ylaI - - S - - - protein conserved in bacteria
CFDGDPAD_00646 5.49e-123 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CFDGDPAD_00647 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
CFDGDPAD_00648 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CFDGDPAD_00649 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
CFDGDPAD_00650 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
CFDGDPAD_00651 2.87e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
CFDGDPAD_00652 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CFDGDPAD_00653 4.04e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
CFDGDPAD_00654 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CFDGDPAD_00655 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
CFDGDPAD_00656 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFDGDPAD_00657 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
CFDGDPAD_00658 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
CFDGDPAD_00659 1.48e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
CFDGDPAD_00660 1.61e-81 ylbA - - S - - - YugN-like family
CFDGDPAD_00661 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
CFDGDPAD_00662 6.24e-256 ylbC - - S - - - protein with SCP PR1 domains
CFDGDPAD_00663 3.24e-89 ylbD - - S - - - Putative coat protein
CFDGDPAD_00664 1.73e-48 ylbE - - S - - - YlbE-like protein
CFDGDPAD_00665 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
CFDGDPAD_00666 5.1e-51 ylbG - - S - - - UPF0298 protein
CFDGDPAD_00667 3.51e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
CFDGDPAD_00668 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFDGDPAD_00669 1.58e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
CFDGDPAD_00670 3.64e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
CFDGDPAD_00671 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
CFDGDPAD_00672 5.94e-301 ylbM - - S - - - Belongs to the UPF0348 family
CFDGDPAD_00674 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
CFDGDPAD_00675 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
CFDGDPAD_00676 1.11e-105 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
CFDGDPAD_00677 1.33e-115 ylbP - - K - - - n-acetyltransferase
CFDGDPAD_00678 9.62e-216 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFDGDPAD_00679 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CFDGDPAD_00680 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
CFDGDPAD_00681 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CFDGDPAD_00682 3.42e-68 ftsL - - D - - - Essential cell division protein
CFDGDPAD_00683 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
CFDGDPAD_00684 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
CFDGDPAD_00685 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFDGDPAD_00686 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFDGDPAD_00687 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFDGDPAD_00688 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
CFDGDPAD_00689 3.15e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFDGDPAD_00690 1.85e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
CFDGDPAD_00691 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CFDGDPAD_00692 4.5e-142 ylxW - - S - - - protein conserved in bacteria
CFDGDPAD_00693 2.43e-122 ylxX - - S - - - protein conserved in bacteria
CFDGDPAD_00694 5.37e-76 sbp - - S - - - small basic protein
CFDGDPAD_00695 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CFDGDPAD_00696 2.14e-259 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFDGDPAD_00697 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
CFDGDPAD_00698 1.06e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
CFDGDPAD_00699 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFDGDPAD_00700 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFDGDPAD_00701 1.57e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
CFDGDPAD_00702 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
CFDGDPAD_00703 1.46e-50 ylmC - - S - - - sporulation protein
CFDGDPAD_00704 9.17e-204 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
CFDGDPAD_00705 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CFDGDPAD_00706 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CFDGDPAD_00707 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
CFDGDPAD_00708 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
CFDGDPAD_00709 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
CFDGDPAD_00710 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFDGDPAD_00711 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
CFDGDPAD_00712 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFDGDPAD_00713 2.04e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
CFDGDPAD_00714 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CFDGDPAD_00715 1.3e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
CFDGDPAD_00716 9.92e-212 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
CFDGDPAD_00717 2.91e-316 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CFDGDPAD_00718 1.08e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
CFDGDPAD_00719 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
CFDGDPAD_00720 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
CFDGDPAD_00721 3.65e-222 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CFDGDPAD_00722 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CFDGDPAD_00723 1.22e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFDGDPAD_00724 1.03e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
CFDGDPAD_00725 1.04e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
CFDGDPAD_00726 2.62e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
CFDGDPAD_00727 1.59e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
CFDGDPAD_00728 4.85e-184 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
CFDGDPAD_00729 1.76e-188 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
CFDGDPAD_00730 2.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
CFDGDPAD_00731 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
CFDGDPAD_00732 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
CFDGDPAD_00733 1.19e-201 yloC - - S - - - stress-induced protein
CFDGDPAD_00734 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
CFDGDPAD_00735 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
CFDGDPAD_00736 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CFDGDPAD_00737 5.98e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFDGDPAD_00738 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CFDGDPAD_00739 2.89e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CFDGDPAD_00740 3.51e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFDGDPAD_00741 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFDGDPAD_00742 5.3e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CFDGDPAD_00743 5.87e-179 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
CFDGDPAD_00744 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
CFDGDPAD_00745 3.92e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CFDGDPAD_00746 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
CFDGDPAD_00747 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
CFDGDPAD_00748 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
CFDGDPAD_00749 3.65e-78 yloU - - S - - - protein conserved in bacteria
CFDGDPAD_00750 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
CFDGDPAD_00751 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
CFDGDPAD_00752 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
CFDGDPAD_00753 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CFDGDPAD_00754 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
CFDGDPAD_00755 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CFDGDPAD_00756 3.09e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
CFDGDPAD_00757 1.17e-165 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
CFDGDPAD_00758 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFDGDPAD_00759 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CFDGDPAD_00760 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
CFDGDPAD_00761 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CFDGDPAD_00762 1.67e-114 - - - - - - - -
CFDGDPAD_00763 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CFDGDPAD_00764 3.95e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFDGDPAD_00765 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
CFDGDPAD_00766 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
CFDGDPAD_00767 9.77e-80 ylqD - - S - - - YlqD protein
CFDGDPAD_00768 1.06e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFDGDPAD_00769 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
CFDGDPAD_00770 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CFDGDPAD_00771 5.7e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CFDGDPAD_00772 5.83e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFDGDPAD_00773 0.0 ylqG - - - - - - -
CFDGDPAD_00774 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
CFDGDPAD_00775 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
CFDGDPAD_00776 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CFDGDPAD_00777 2.66e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
CFDGDPAD_00778 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFDGDPAD_00779 1.1e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CFDGDPAD_00780 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
CFDGDPAD_00781 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CFDGDPAD_00782 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CFDGDPAD_00783 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CFDGDPAD_00784 1.62e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
CFDGDPAD_00785 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
CFDGDPAD_00786 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
CFDGDPAD_00787 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
CFDGDPAD_00788 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CFDGDPAD_00789 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
CFDGDPAD_00790 7.06e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
CFDGDPAD_00791 7.27e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
CFDGDPAD_00792 1.02e-83 ylxF - - S - - - MgtE intracellular N domain
CFDGDPAD_00793 1.28e-311 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
CFDGDPAD_00794 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
CFDGDPAD_00795 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
CFDGDPAD_00796 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
CFDGDPAD_00797 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CFDGDPAD_00798 3.77e-251 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CFDGDPAD_00799 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
CFDGDPAD_00800 7.53e-135 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
CFDGDPAD_00801 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
CFDGDPAD_00802 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
CFDGDPAD_00803 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
CFDGDPAD_00804 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFDGDPAD_00805 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CFDGDPAD_00806 1.62e-255 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
CFDGDPAD_00807 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
CFDGDPAD_00808 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
CFDGDPAD_00809 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
CFDGDPAD_00810 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
CFDGDPAD_00811 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
CFDGDPAD_00812 1.36e-111 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
CFDGDPAD_00813 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFDGDPAD_00814 6.62e-99 ylxL - - - - - - -
CFDGDPAD_00815 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
CFDGDPAD_00816 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFDGDPAD_00817 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
CFDGDPAD_00818 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CFDGDPAD_00819 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFDGDPAD_00820 1.36e-177 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
CFDGDPAD_00821 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
CFDGDPAD_00822 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
CFDGDPAD_00823 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CFDGDPAD_00824 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFDGDPAD_00825 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
CFDGDPAD_00826 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
CFDGDPAD_00827 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
CFDGDPAD_00828 6.16e-63 ylxQ - - J - - - ribosomal protein
CFDGDPAD_00829 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFDGDPAD_00830 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
CFDGDPAD_00831 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFDGDPAD_00832 6.04e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFDGDPAD_00833 3.84e-231 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
CFDGDPAD_00834 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFDGDPAD_00835 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CFDGDPAD_00836 1.69e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
CFDGDPAD_00837 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
CFDGDPAD_00838 1.53e-56 ymxH - - S - - - YlmC YmxH family
CFDGDPAD_00839 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
CFDGDPAD_00840 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
CFDGDPAD_00841 4.77e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CFDGDPAD_00842 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
CFDGDPAD_00843 1.57e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFDGDPAD_00844 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CFDGDPAD_00845 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
CFDGDPAD_00846 8.23e-43 - - - S - - - YlzJ-like protein
CFDGDPAD_00847 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
CFDGDPAD_00848 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_00849 8.48e-267 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CFDGDPAD_00850 3.45e-301 albE - - S - - - Peptidase M16
CFDGDPAD_00851 5.35e-306 ymfH - - S - - - zinc protease
CFDGDPAD_00852 1.74e-165 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
CFDGDPAD_00853 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
CFDGDPAD_00854 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
CFDGDPAD_00855 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
CFDGDPAD_00856 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFDGDPAD_00857 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
CFDGDPAD_00858 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFDGDPAD_00859 5.92e-280 pbpX - - V - - - Beta-lactamase
CFDGDPAD_00860 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
CFDGDPAD_00861 3.57e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
CFDGDPAD_00862 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
CFDGDPAD_00863 3.02e-255 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
CFDGDPAD_00864 1.02e-278 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CFDGDPAD_00865 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CFDGDPAD_00866 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
CFDGDPAD_00867 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
CFDGDPAD_00868 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFDGDPAD_00869 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFDGDPAD_00870 1.64e-92 - - - S - - - Regulatory protein YrvL
CFDGDPAD_00871 7.96e-127 ymcC - - S - - - Membrane
CFDGDPAD_00872 1.2e-140 pksA - - K - - - Transcriptional regulator
CFDGDPAD_00873 4.02e-167 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
CFDGDPAD_00874 5.32e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
CFDGDPAD_00876 9.87e-238 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
CFDGDPAD_00877 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
CFDGDPAD_00878 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
CFDGDPAD_00879 4.36e-303 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CFDGDPAD_00880 1.13e-312 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
CFDGDPAD_00881 8.31e-183 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
CFDGDPAD_00882 1.5e-174 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
CFDGDPAD_00883 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
CFDGDPAD_00884 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
CFDGDPAD_00885 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
CFDGDPAD_00886 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
CFDGDPAD_00887 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
CFDGDPAD_00888 4.13e-296 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
CFDGDPAD_00889 8.03e-81 ymzB - - - - - - -
CFDGDPAD_00890 4.61e-208 - - - S - - - Metallo-beta-lactamase superfamily
CFDGDPAD_00891 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
CFDGDPAD_00893 3.96e-163 ymaC - - S - - - Replication protein
CFDGDPAD_00894 1.21e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
CFDGDPAD_00895 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
CFDGDPAD_00896 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
CFDGDPAD_00898 5.41e-76 ymaF - - S - - - YmaF family
CFDGDPAD_00899 2.28e-222 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFDGDPAD_00900 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
CFDGDPAD_00901 1.63e-31 - - - - - - - -
CFDGDPAD_00902 1.2e-30 ymzA - - - - - - -
CFDGDPAD_00903 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
CFDGDPAD_00904 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFDGDPAD_00905 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFDGDPAD_00906 2.24e-141 - - - - - - - -
CFDGDPAD_00907 1.11e-147 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
CFDGDPAD_00908 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
CFDGDPAD_00909 1.74e-291 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFDGDPAD_00910 1.67e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
CFDGDPAD_00911 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
CFDGDPAD_00912 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
CFDGDPAD_00913 1.04e-195 - - - L - - - Belongs to the 'phage' integrase family
CFDGDPAD_00914 5.51e-85 - - - S - - - SMI1 / KNR4 family
CFDGDPAD_00915 1.55e-75 - - - S - - - DNase/tRNase domain of colicin-like bacteriocin
CFDGDPAD_00916 4.55e-165 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
CFDGDPAD_00917 1.69e-48 - - - - - - - -
CFDGDPAD_00918 2.72e-75 - - - - - - - -
CFDGDPAD_00919 5.86e-84 - - - G - - - SMI1-KNR4 cell-wall
CFDGDPAD_00920 0.0 - - - UW ko:K21487,ko:K21489,ko:K21491,ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
CFDGDPAD_00921 8.91e-121 - - - S ko:K21490 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
CFDGDPAD_00922 8.42e-121 yokK - - S - - - SMI1 / KNR4 family
CFDGDPAD_00923 6.15e-127 - - - J - - - Acetyltransferase (GNAT) domain
CFDGDPAD_00925 8.09e-53 - - - - - - - -
CFDGDPAD_00926 5.01e-69 - - - S - - - YolD-like protein
CFDGDPAD_00927 1.76e-298 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFDGDPAD_00929 1.21e-264 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
CFDGDPAD_00930 1.14e-48 - - - S - - - Bacteriophage holin
CFDGDPAD_00932 8.07e-109 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
CFDGDPAD_00934 2.68e-146 - - - - - - - -
CFDGDPAD_00935 0.0 - - - S - - - Pfam Transposase IS66
CFDGDPAD_00936 1.52e-109 - - - S - - - Phage tail protein
CFDGDPAD_00937 0.0 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CFDGDPAD_00938 0.0 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CFDGDPAD_00939 3.93e-150 - - - - - - - -
CFDGDPAD_00944 7.88e-244 - - - A - - - Belongs to the 'phage' integrase family
CFDGDPAD_00945 1.58e-91 - - - - - - - -
CFDGDPAD_00946 1.27e-91 - - - - - - - -
CFDGDPAD_00949 9.84e-81 - - - S - - - Domain of unknown function (DUF2479)
CFDGDPAD_00950 1.1e-67 - - - - - - - -
CFDGDPAD_00953 5.27e-144 - - - - - - - -
CFDGDPAD_00954 3.98e-168 - - - - - - - -
CFDGDPAD_00955 3.61e-117 - - - - - - - -
CFDGDPAD_00956 9.48e-157 - - - - - - - -
CFDGDPAD_00958 8.95e-91 - - - - - - - -
CFDGDPAD_00959 2.31e-105 - - - - - - - -
CFDGDPAD_00960 3.43e-236 - - - - - - - -
CFDGDPAD_00961 2.05e-121 - - - - - - - -
CFDGDPAD_00962 0.0 - - - - - - - -
CFDGDPAD_00963 0.0 - - - - - - - -
CFDGDPAD_00964 0.0 - - - S - - - Terminase-like family
CFDGDPAD_00965 1.93e-218 - - - - - - - -
CFDGDPAD_00969 9.19e-267 - - - S - - - Calcineurin-like phosphoesterase superfamily domain
CFDGDPAD_00972 1.19e-252 - - - - - - - -
CFDGDPAD_00973 2.87e-48 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CFDGDPAD_00974 7.12e-100 - - - - - - - -
CFDGDPAD_00975 1.3e-07 - - - S - - - nucleic acid binding
CFDGDPAD_00976 0.0 - - - - - - - -
CFDGDPAD_00979 1.05e-260 - - - - - - - -
CFDGDPAD_00986 7.31e-151 - - - - - - - -
CFDGDPAD_00987 2.09e-45 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
CFDGDPAD_00990 2.26e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
CFDGDPAD_00992 2.35e-95 - - - K - - - Divergent AAA domain
CFDGDPAD_00998 1.55e-40 - - - - - - - -
CFDGDPAD_00999 1.55e-125 - - - - - - - -
CFDGDPAD_01001 8.3e-161 - - - - - - - -
CFDGDPAD_01006 3.39e-253 - - - L - - - Belongs to the 'phage' integrase family
CFDGDPAD_01007 0.0 - - - S - - - DNA-sulfur modification-associated
CFDGDPAD_01008 4.11e-226 - - - - - - - -
CFDGDPAD_01009 4.78e-46 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_01021 3.21e-115 - - - S - - - Protein of unknown function (DUF1273)
CFDGDPAD_01024 1.65e-52 - - - - - - - -
CFDGDPAD_01030 7.6e-106 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 deoxyuridine 5'-triphosphate nucleotidohydrolase
CFDGDPAD_01032 6.43e-96 - - - - - - - -
CFDGDPAD_01033 4.3e-189 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
CFDGDPAD_01034 9.79e-105 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
CFDGDPAD_01035 2.89e-30 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
CFDGDPAD_01037 2.23e-239 - - - - - - - -
CFDGDPAD_01042 1.22e-196 - - - - - - - -
CFDGDPAD_01043 5.21e-228 - - - L - - - AAA domain
CFDGDPAD_01044 1.83e-111 - - - - - - - -
CFDGDPAD_01045 0.0 - - - J - - - DnaB-like helicase C terminal domain
CFDGDPAD_01046 1.06e-282 - - - L - - - DNA primase activity
CFDGDPAD_01047 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
CFDGDPAD_01048 0.0 - - - S - - - Bacterial DNA polymerase III alpha subunit
CFDGDPAD_01049 1.09e-142 - - - S - - - protein conserved in bacteria
CFDGDPAD_01054 6.25e-112 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
CFDGDPAD_01055 5.71e-116 yorS - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CFDGDPAD_01056 2.34e-109 - 2.7.6.1 - EF ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl synthetase-associated domain
CFDGDPAD_01057 2.77e-249 - 2.4.2.12 - H ko:K03462 ko00760,ko01100,ko04621,map00760,map01100,map04621 ko00000,ko00001,ko01000 Nicotinate phosphoribosyltransferase (NAPRTase) family
CFDGDPAD_01073 2.28e-84 - - - S - - - NrdI Flavodoxin like
CFDGDPAD_01074 1.27e-156 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFDGDPAD_01075 1.54e-47 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFDGDPAD_01076 2.63e-207 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFDGDPAD_01078 7.13e-136 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFDGDPAD_01079 1.07e-125 - - - L - - - HNH endonuclease
CFDGDPAD_01080 8.45e-71 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFDGDPAD_01081 4.57e-49 - - - O - - - Glutaredoxin
CFDGDPAD_01082 2.11e-97 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
CFDGDPAD_01083 4.01e-20 XK27_09885 - - V - - - COG4767 Glycopeptide antibiotics resistance protein
CFDGDPAD_01086 2.12e-50 - - - S - - - Protein of unknown function (DUF1643)
CFDGDPAD_01087 1.41e-203 - - - S - - - Thymidylate synthase
CFDGDPAD_01088 4.67e-39 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CFDGDPAD_01091 1.14e-31 - - - - - - - -
CFDGDPAD_01092 2.24e-41 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
CFDGDPAD_01093 3.08e-205 - - - S - - - Calcineurin-like phosphoesterase
CFDGDPAD_01096 5.49e-34 - - - - - - - -
CFDGDPAD_01098 2.22e-40 - - - S - - - Macro domain
CFDGDPAD_01101 4.77e-116 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CFDGDPAD_01102 3.39e-37 - - - - - - - -
CFDGDPAD_01103 3.06e-14 - - - - - - - -
CFDGDPAD_01105 4.12e-80 - - - Q - - - Collagen triple helix repeat (20 copies)
CFDGDPAD_01106 1.12e-118 - - - M - - - Glycosyltransferase like family
CFDGDPAD_01107 1.17e-155 - - - H - - - Methionine biosynthesis protein MetW
CFDGDPAD_01108 2.47e-247 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
CFDGDPAD_01109 1.1e-274 - - - H - - - N-terminal domain of galactosyltransferase
CFDGDPAD_01111 9.7e-125 ynaD - - J - - - Acetyltransferase (GNAT) domain
CFDGDPAD_01113 9.9e-95 - - - S - - - CAAX protease self-immunity
CFDGDPAD_01115 3.39e-31 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
CFDGDPAD_01116 2.3e-144 - - - S - - - Domain of unknown function (DUF3885)
CFDGDPAD_01119 6.62e-105 - - - E - - - phosphoribosylanthranilate isomerase activity
CFDGDPAD_01120 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
CFDGDPAD_01121 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
CFDGDPAD_01122 3.02e-276 xylR - - GK - - - ROK family
CFDGDPAD_01123 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
CFDGDPAD_01124 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
CFDGDPAD_01125 2.51e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
CFDGDPAD_01126 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CFDGDPAD_01127 5.91e-279 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFDGDPAD_01128 1.22e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
CFDGDPAD_01131 3.91e-210 - - - S - - - Thymidylate synthase
CFDGDPAD_01132 8.27e-40 - - - - - - - -
CFDGDPAD_01134 1.55e-172 - - - S - - - Domain of unknown function, YrpD
CFDGDPAD_01137 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
CFDGDPAD_01138 8.92e-96 - - - - - - - -
CFDGDPAD_01139 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
CFDGDPAD_01142 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
CFDGDPAD_01143 1.95e-250 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
CFDGDPAD_01144 9.64e-290 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
CFDGDPAD_01145 8.78e-197 yndG - - S - - - DoxX-like family
CFDGDPAD_01146 4.21e-150 - - - S - - - Domain of unknown function (DUF4166)
CFDGDPAD_01147 0.0 yndJ - - S - - - YndJ-like protein
CFDGDPAD_01149 3.97e-176 yndL - - S - - - Replication protein
CFDGDPAD_01150 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
CFDGDPAD_01151 3.01e-102 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
CFDGDPAD_01152 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CFDGDPAD_01153 2.44e-64 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
CFDGDPAD_01154 3.8e-143 yneB - - L - - - resolvase
CFDGDPAD_01155 1.15e-43 ynzC - - S - - - UPF0291 protein
CFDGDPAD_01156 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CFDGDPAD_01157 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
CFDGDPAD_01158 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
CFDGDPAD_01159 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
CFDGDPAD_01160 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
CFDGDPAD_01161 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
CFDGDPAD_01162 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
CFDGDPAD_01163 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
CFDGDPAD_01164 1.21e-86 cotM - - O ko:K06335 - ko00000 Spore coat protein
CFDGDPAD_01165 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
CFDGDPAD_01166 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
CFDGDPAD_01167 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFDGDPAD_01168 3.74e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CFDGDPAD_01169 9.26e-10 - - - S - - - Fur-regulated basic protein B
CFDGDPAD_01171 1.9e-47 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
CFDGDPAD_01172 1.4e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
CFDGDPAD_01173 1.63e-71 yneQ - - - - - - -
CFDGDPAD_01174 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
CFDGDPAD_01175 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CFDGDPAD_01176 7e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
CFDGDPAD_01177 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CFDGDPAD_01178 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CFDGDPAD_01179 1.82e-18 - - - - - - - -
CFDGDPAD_01180 1.06e-75 ynfC - - - - - - -
CFDGDPAD_01181 9.17e-303 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
CFDGDPAD_01182 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
CFDGDPAD_01184 3.94e-316 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
CFDGDPAD_01185 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
CFDGDPAD_01186 1.04e-104 yngA - - S - - - membrane
CFDGDPAD_01187 3.73e-208 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
CFDGDPAD_01188 2.01e-134 yngC - - S - - - membrane-associated protein
CFDGDPAD_01189 9e-297 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
CFDGDPAD_01190 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CFDGDPAD_01191 4.25e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
CFDGDPAD_01192 1.36e-211 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
CFDGDPAD_01193 2.4e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
CFDGDPAD_01194 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
CFDGDPAD_01195 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CFDGDPAD_01196 1.53e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
CFDGDPAD_01197 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
CFDGDPAD_01198 6.08e-84 yngL - - S - - - Protein of unknown function (DUF1360)
CFDGDPAD_01199 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
CFDGDPAD_01200 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDGDPAD_01201 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFDGDPAD_01202 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFDGDPAD_01203 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
CFDGDPAD_01204 4.54e-264 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFDGDPAD_01205 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
CFDGDPAD_01206 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CFDGDPAD_01207 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFDGDPAD_01208 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CFDGDPAD_01209 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CFDGDPAD_01210 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
CFDGDPAD_01211 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CFDGDPAD_01212 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CFDGDPAD_01213 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
CFDGDPAD_01214 2.58e-192 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
CFDGDPAD_01215 1.87e-97 - - - S - - - Bacterial PH domain
CFDGDPAD_01216 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
CFDGDPAD_01217 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
CFDGDPAD_01218 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
CFDGDPAD_01219 5.34e-227 yyaD - - S - - - Membrane
CFDGDPAD_01220 7.41e-45 yyzM - - S - - - protein conserved in bacteria
CFDGDPAD_01221 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CFDGDPAD_01222 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CFDGDPAD_01223 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
CFDGDPAD_01224 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CFDGDPAD_01225 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFDGDPAD_01226 3.43e-186 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
CFDGDPAD_01227 1.44e-228 ccpB - - K - - - Transcriptional regulator
CFDGDPAD_01228 1.64e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CFDGDPAD_01229 3.81e-129 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
CFDGDPAD_01230 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
CFDGDPAD_01231 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
CFDGDPAD_01232 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
CFDGDPAD_01233 1.99e-207 - - - EG - - - EamA-like transporter family
CFDGDPAD_01234 1.34e-88 - - - K - - - MerR HTH family regulatory protein
CFDGDPAD_01235 9.96e-30 - - - K - - - acetyltransferase
CFDGDPAD_01236 4.98e-20 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
CFDGDPAD_01237 8.28e-135 yyaP - - H - - - RibD C-terminal domain
CFDGDPAD_01238 4.29e-85 - - - S - - - YjbR
CFDGDPAD_01239 2.72e-119 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
CFDGDPAD_01240 4.28e-125 yyaS - - S ko:K07149 - ko00000 Membrane
CFDGDPAD_01241 2.07e-90 yjcF - - S - - - Acetyltransferase (GNAT) domain
CFDGDPAD_01242 4.54e-100 yybA - - K - - - transcriptional
CFDGDPAD_01243 6.18e-164 - - - S - - - Metallo-beta-lactamase superfamily
CFDGDPAD_01244 2.99e-98 yybC - - - - - - -
CFDGDPAD_01245 1.87e-102 yjcF - - S - - - Acetyltransferase (GNAT) domain
CFDGDPAD_01246 1.07e-209 yybE - - K - - - Transcriptional regulator
CFDGDPAD_01247 2.13e-277 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CFDGDPAD_01248 3.81e-160 yybG - - S - - - Pentapeptide repeat-containing protein
CFDGDPAD_01249 3.02e-88 - - - S - - - SnoaL-like domain
CFDGDPAD_01250 9.72e-182 - - - - - - - -
CFDGDPAD_01251 1.25e-141 - - - K - - - TipAS antibiotic-recognition domain
CFDGDPAD_01252 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CFDGDPAD_01254 3.19e-90 - - - - - - - -
CFDGDPAD_01255 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
CFDGDPAD_01256 6.43e-88 yybR - - K - - - Transcriptional regulator
CFDGDPAD_01257 6.83e-109 cotF - - M ko:K06329 - ko00000 Spore coat protein
CFDGDPAD_01259 2.13e-204 yybS - - S - - - membrane
CFDGDPAD_01260 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
CFDGDPAD_01261 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
CFDGDPAD_01262 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CFDGDPAD_01263 1.4e-281 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
CFDGDPAD_01264 1.89e-22 yycC - - K - - - YycC-like protein
CFDGDPAD_01266 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
CFDGDPAD_01267 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
CFDGDPAD_01268 1.4e-100 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CFDGDPAD_01269 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFDGDPAD_01274 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDGDPAD_01275 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFDGDPAD_01276 0.0 yycH - - S - - - protein conserved in bacteria
CFDGDPAD_01277 2.83e-199 yycI - - S - - - protein conserved in bacteria
CFDGDPAD_01278 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
CFDGDPAD_01279 6.09e-275 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFDGDPAD_01280 1.74e-41 - - - S - - - Peptidase propeptide and YPEB domain
CFDGDPAD_01281 2.01e-99 - - - S - - - Peptidase propeptide and YPEB domain
CFDGDPAD_01282 2.36e-122 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
CFDGDPAD_01283 9.16e-215 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
CFDGDPAD_01284 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
CFDGDPAD_01285 2.89e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
CFDGDPAD_01286 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
CFDGDPAD_01287 6.49e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
CFDGDPAD_01289 3.54e-238 - - - S - - - aspartate phosphatase
CFDGDPAD_01290 1.45e-108 yycN - - K - - - Acetyltransferase
CFDGDPAD_01291 2.78e-168 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CFDGDPAD_01292 3.92e-269 yycP - - - - - - -
CFDGDPAD_01293 4.53e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
CFDGDPAD_01295 1.05e-296 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CFDGDPAD_01296 1.3e-86 - - - - - - - -
CFDGDPAD_01298 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CFDGDPAD_01299 0.0 - - - L - - - helicase superfamily c-terminal domain
CFDGDPAD_01300 1.22e-106 - - - S - - - Domain of unknown function (DUF1837)
CFDGDPAD_01301 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
CFDGDPAD_01302 2.4e-23 - - - - - - - -
CFDGDPAD_01304 1.86e-196 - - - - - - - -
CFDGDPAD_01305 4.48e-12 - 3.4.24.84 - O ko:K03799,ko:K06013 ko00900,ko01130,map00900,map01130 ko00000,ko00001,ko00002,ko01000,ko01002,ko04147 metalloendopeptidase activity
CFDGDPAD_01306 0.0 - - - L - - - COG0210 Superfamily I DNA and RNA helicases
CFDGDPAD_01307 1.23e-162 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_01308 7.28e-42 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
CFDGDPAD_01309 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CFDGDPAD_01310 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
CFDGDPAD_01311 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
CFDGDPAD_01312 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CFDGDPAD_01313 5.87e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
CFDGDPAD_01314 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
CFDGDPAD_01315 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
CFDGDPAD_01316 2.33e-263 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
CFDGDPAD_01317 1.79e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
CFDGDPAD_01318 3.63e-152 yxaC - - M - - - effector of murein hydrolase
CFDGDPAD_01319 5.1e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
CFDGDPAD_01320 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
CFDGDPAD_01321 1.23e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDGDPAD_01322 3.91e-130 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
CFDGDPAD_01323 2.11e-250 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
CFDGDPAD_01324 6.77e-289 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
CFDGDPAD_01325 4.7e-98 yxaI - - S - - - membrane protein domain
CFDGDPAD_01326 1.38e-83 - - - S - - - Family of unknown function (DUF5391)
CFDGDPAD_01327 3.47e-135 yxaL - - S - - - PQQ-like domain
CFDGDPAD_01328 1.67e-13 - - - S - - - RDD family
CFDGDPAD_01329 7.19e-315 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
CFDGDPAD_01330 6.51e-269 yxbF - - K - - - Bacterial regulatory proteins, tetR family
CFDGDPAD_01331 5.66e-191 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
CFDGDPAD_01333 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
CFDGDPAD_01334 5.91e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CFDGDPAD_01335 8.67e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
CFDGDPAD_01337 1.74e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
CFDGDPAD_01338 6.35e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
CFDGDPAD_01339 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CFDGDPAD_01340 4.9e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
CFDGDPAD_01341 2.48e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
CFDGDPAD_01342 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
CFDGDPAD_01343 8.63e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
CFDGDPAD_01344 1.99e-296 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
CFDGDPAD_01345 1.55e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
CFDGDPAD_01346 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
CFDGDPAD_01347 8.93e-186 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
CFDGDPAD_01348 2.43e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
CFDGDPAD_01349 3.27e-159 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDGDPAD_01350 6.35e-230 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFDGDPAD_01351 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_01352 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
CFDGDPAD_01353 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
CFDGDPAD_01354 9.01e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CFDGDPAD_01355 3.46e-82 - - - - - - - -
CFDGDPAD_01356 3.06e-27 yxeD - - - - - - -
CFDGDPAD_01357 7.32e-42 yxeE - - - - - - -
CFDGDPAD_01360 2.32e-193 yxeH - - S - - - hydrolases of the HAD superfamily
CFDGDPAD_01361 1.11e-236 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
CFDGDPAD_01362 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFDGDPAD_01363 2.19e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFDGDPAD_01364 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
CFDGDPAD_01365 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
CFDGDPAD_01366 6.82e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_01367 7.09e-273 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
CFDGDPAD_01368 5.04e-315 yxeQ - - S - - - MmgE/PrpD family
CFDGDPAD_01369 6.62e-257 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
CFDGDPAD_01370 9.11e-198 - - - S - - - Domain of Unknown Function (DUF1206)
CFDGDPAD_01371 1.22e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CFDGDPAD_01372 8.3e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CFDGDPAD_01373 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CFDGDPAD_01374 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
CFDGDPAD_01375 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
CFDGDPAD_01376 4.15e-232 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
CFDGDPAD_01377 2.72e-300 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
CFDGDPAD_01378 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CFDGDPAD_01379 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
CFDGDPAD_01380 7.02e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
CFDGDPAD_01381 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
CFDGDPAD_01382 2.45e-192 - - - L - - - Protein of unknown function (DUF2726)
CFDGDPAD_01383 6.09e-79 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
CFDGDPAD_01384 0.0 - - - L - - - HKD family nuclease
CFDGDPAD_01385 3.59e-35 - - - S - - - Domain of unknown function (DUF5082)
CFDGDPAD_01386 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
CFDGDPAD_01387 4.05e-274 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
CFDGDPAD_01388 8.25e-69 - - - - - - - -
CFDGDPAD_01389 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CFDGDPAD_01390 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CFDGDPAD_01391 3.46e-94 yxiE - - T - - - Belongs to the universal stress protein A family
CFDGDPAD_01392 5.53e-158 - 1.14.11.45 - E ko:K20418 - ko00000,ko01000 2OG-Fe dioxygenase
CFDGDPAD_01393 2.01e-162 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDGDPAD_01394 1.7e-209 yxxF - - EG - - - EamA-like transporter family
CFDGDPAD_01395 0.0 wapA - - M - - - COG3209 Rhs family protein
CFDGDPAD_01396 1.27e-69 - - - - - - - -
CFDGDPAD_01398 5.12e-161 - - - - - - - -
CFDGDPAD_01399 1.8e-118 - - - S - - - Protein of unknown function (DUF4240)
CFDGDPAD_01400 2.22e-103 - - - - - - - -
CFDGDPAD_01401 1.53e-65 - - - - - - - -
CFDGDPAD_01402 6.12e-47 yxiG - - - - - - -
CFDGDPAD_01403 2.78e-67 yxxG - - - - - - -
CFDGDPAD_01404 6.09e-50 - - - S - - - Protein of unknown function (DUF2750)
CFDGDPAD_01407 1.62e-171 - - - - - - - -
CFDGDPAD_01408 1.95e-109 yxiI - - S - - - Protein of unknown function (DUF2716)
CFDGDPAD_01409 3.22e-55 yxiJ - - S - - - YxiJ-like protein
CFDGDPAD_01412 5e-274 - - - E - - - GDSL-like Lipase/Acylhydrolase
CFDGDPAD_01413 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
CFDGDPAD_01414 1.22e-288 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
CFDGDPAD_01415 5.09e-141 - - - - - - - -
CFDGDPAD_01416 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
CFDGDPAD_01417 1.25e-183 bglS - - M - - - licheninase activity
CFDGDPAD_01418 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
CFDGDPAD_01419 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
CFDGDPAD_01420 2.28e-63 yxiS - - - - - - -
CFDGDPAD_01421 1.78e-134 - - - T - - - Domain of unknown function (DUF4163)
CFDGDPAD_01422 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CFDGDPAD_01423 1.7e-201 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
CFDGDPAD_01424 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
CFDGDPAD_01425 6.6e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CFDGDPAD_01426 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CFDGDPAD_01427 5.83e-176 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
CFDGDPAD_01428 3.13e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
CFDGDPAD_01429 2.13e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
CFDGDPAD_01430 7.94e-109 yxjI - - S - - - LURP-one-related
CFDGDPAD_01433 2.13e-296 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
CFDGDPAD_01434 1.74e-144 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
CFDGDPAD_01435 1.13e-257 - - - T - - - Signal transduction histidine kinase
CFDGDPAD_01436 2.68e-100 - - - S - - - Protein of unknown function (DUF1453)
CFDGDPAD_01437 1.74e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
CFDGDPAD_01438 2.67e-187 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
CFDGDPAD_01439 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CFDGDPAD_01440 1.12e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
CFDGDPAD_01441 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CFDGDPAD_01442 8.75e-198 yxkH - - G - - - Polysaccharide deacetylase
CFDGDPAD_01444 0.0 - - - O - - - Peptidase family M48
CFDGDPAD_01445 2.67e-308 cimH - - C - - - COG3493 Na citrate symporter
CFDGDPAD_01446 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
CFDGDPAD_01447 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
CFDGDPAD_01448 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
CFDGDPAD_01449 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
CFDGDPAD_01450 3.07e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CFDGDPAD_01451 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
CFDGDPAD_01452 1.06e-123 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CFDGDPAD_01453 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
CFDGDPAD_01454 1.75e-43 - - - - - - - -
CFDGDPAD_01455 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
CFDGDPAD_01456 1.93e-209 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_01457 1.88e-177 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CFDGDPAD_01458 1.01e-273 yxlH - - EGP - - - Major Facilitator Superfamily
CFDGDPAD_01459 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
CFDGDPAD_01460 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
CFDGDPAD_01461 8.94e-28 yxzF - - - - - - -
CFDGDPAD_01462 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
CFDGDPAD_01463 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
CFDGDPAD_01464 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CFDGDPAD_01465 1.3e-49 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CFDGDPAD_01466 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CFDGDPAD_01467 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
CFDGDPAD_01468 4.83e-177 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDGDPAD_01469 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CFDGDPAD_01470 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDGDPAD_01471 1.88e-296 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
CFDGDPAD_01472 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDGDPAD_01473 5.95e-212 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
CFDGDPAD_01474 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
CFDGDPAD_01475 3.96e-165 - - - EGP - - - Permeases of the major facilitator superfamily
CFDGDPAD_01476 5.58e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
CFDGDPAD_01477 5.37e-116 - - - K - - - Helix-turn-helix XRE-family like proteins
CFDGDPAD_01478 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
CFDGDPAD_01479 4.11e-293 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFDGDPAD_01480 1.25e-114 ywaE - - K - - - Transcriptional regulator
CFDGDPAD_01481 6.76e-156 ywaF - - S - - - Integral membrane protein
CFDGDPAD_01482 5.37e-216 gspA - - M - - - General stress
CFDGDPAD_01483 9.07e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
CFDGDPAD_01484 1.19e-311 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CFDGDPAD_01485 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
CFDGDPAD_01486 2.6e-314 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CFDGDPAD_01487 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
CFDGDPAD_01488 2.31e-279 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
CFDGDPAD_01489 6.33e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
CFDGDPAD_01490 2.91e-275 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
CFDGDPAD_01491 1.21e-143 ywbG - - M - - - effector of murein hydrolase
CFDGDPAD_01492 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
CFDGDPAD_01493 1.56e-202 ywbI - - K - - - Transcriptional regulator
CFDGDPAD_01494 3.25e-185 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CFDGDPAD_01495 3.5e-146 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CFDGDPAD_01496 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
CFDGDPAD_01497 6.92e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
CFDGDPAD_01498 5.13e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
CFDGDPAD_01499 3.12e-142 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
CFDGDPAD_01500 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFDGDPAD_01501 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
CFDGDPAD_01503 9.8e-158 ywcC - - K - - - transcriptional regulator
CFDGDPAD_01504 3.88e-76 gtcA - - S - - - GtrA-like protein
CFDGDPAD_01505 3.76e-289 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CFDGDPAD_01506 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
CFDGDPAD_01507 5.11e-49 ydaS - - S - - - membrane
CFDGDPAD_01508 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
CFDGDPAD_01509 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CFDGDPAD_01510 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
CFDGDPAD_01511 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
CFDGDPAD_01512 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
CFDGDPAD_01513 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
CFDGDPAD_01514 9.4e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
CFDGDPAD_01515 3.44e-238 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFDGDPAD_01516 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
CFDGDPAD_01518 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
CFDGDPAD_01519 2.91e-180 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
CFDGDPAD_01520 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CFDGDPAD_01521 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
CFDGDPAD_01522 6.19e-39 ywdA - - - - - - -
CFDGDPAD_01523 2.21e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
CFDGDPAD_01524 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
CFDGDPAD_01525 2.4e-143 ywdD - - - - - - -
CFDGDPAD_01527 4.68e-192 ywdF - - S - - - Glycosyltransferase like family 2
CFDGDPAD_01528 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFDGDPAD_01529 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
CFDGDPAD_01530 9.23e-65 ywdI - - S - - - Family of unknown function (DUF5327)
CFDGDPAD_01531 1.86e-303 ywdJ - - F - - - Xanthine uracil
CFDGDPAD_01532 1.59e-78 ywdK - - S - - - small membrane protein
CFDGDPAD_01533 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
CFDGDPAD_01534 1.9e-185 spsA - - M - - - Spore Coat
CFDGDPAD_01535 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
CFDGDPAD_01536 8.77e-283 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
CFDGDPAD_01537 8.51e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
CFDGDPAD_01538 2.27e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
CFDGDPAD_01539 1.74e-164 spsF - - M ko:K07257 - ko00000 Spore Coat
CFDGDPAD_01540 5.73e-240 spsG - - M - - - Spore Coat
CFDGDPAD_01541 2.14e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CFDGDPAD_01542 1.51e-232 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CFDGDPAD_01543 3.32e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CFDGDPAD_01544 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
CFDGDPAD_01545 3.7e-101 - - - - - - - -
CFDGDPAD_01546 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
CFDGDPAD_01547 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
CFDGDPAD_01548 0.0 rocB - - E - - - arginine degradation protein
CFDGDPAD_01549 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
CFDGDPAD_01550 4.44e-274 ywfA - - EGP - - - -transporter
CFDGDPAD_01551 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
CFDGDPAD_01552 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
CFDGDPAD_01553 4.47e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDGDPAD_01554 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
CFDGDPAD_01555 1.31e-266 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
CFDGDPAD_01556 2.21e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
CFDGDPAD_01557 1.67e-176 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
CFDGDPAD_01558 1.4e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
CFDGDPAD_01559 4.79e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
CFDGDPAD_01560 2.16e-208 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_01561 1.45e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
CFDGDPAD_01562 3.7e-203 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
CFDGDPAD_01563 6.58e-146 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
CFDGDPAD_01564 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
CFDGDPAD_01565 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
CFDGDPAD_01566 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
CFDGDPAD_01567 1.28e-102 yffB - - K - - - Transcriptional regulator
CFDGDPAD_01568 3.9e-303 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
CFDGDPAD_01570 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFDGDPAD_01571 1.76e-94 ywhA - - K - - - Transcriptional regulator
CFDGDPAD_01572 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
CFDGDPAD_01573 3.29e-154 ywhC - - S - - - Peptidase family M50
CFDGDPAD_01574 7.83e-123 ywhD - - S - - - YwhD family
CFDGDPAD_01575 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
CFDGDPAD_01576 6.45e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CFDGDPAD_01577 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
CFDGDPAD_01579 5.77e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
CFDGDPAD_01580 9.47e-275 ywhK - - CO - - - amine dehydrogenase activity
CFDGDPAD_01581 9.08e-317 ywhL - - CO - - - amine dehydrogenase activity
CFDGDPAD_01583 1.89e-314 - - - L - - - Peptidase, M16
CFDGDPAD_01584 4.48e-272 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
CFDGDPAD_01585 2.31e-295 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
CFDGDPAD_01586 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
CFDGDPAD_01588 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
CFDGDPAD_01589 3.71e-12 - - - S - - - Bacteriocin subtilosin A
CFDGDPAD_01590 4.64e-96 ywiB - - S - - - protein conserved in bacteria
CFDGDPAD_01591 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
CFDGDPAD_01592 1.7e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
CFDGDPAD_01593 3.27e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
CFDGDPAD_01594 5.62e-117 ywiC - - S - - - YwiC-like protein
CFDGDPAD_01595 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
CFDGDPAD_01596 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CFDGDPAD_01597 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
CFDGDPAD_01598 7.94e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
CFDGDPAD_01599 2.06e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
CFDGDPAD_01600 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFDGDPAD_01601 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
CFDGDPAD_01602 1.35e-124 ywjB - - H - - - RibD C-terminal domain
CFDGDPAD_01603 1.32e-57 ywjC - - - - - - -
CFDGDPAD_01604 8.09e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
CFDGDPAD_01605 8.56e-290 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
CFDGDPAD_01606 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
CFDGDPAD_01607 4.95e-268 acdA - - I - - - acyl-CoA dehydrogenase
CFDGDPAD_01608 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CFDGDPAD_01609 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CFDGDPAD_01610 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
CFDGDPAD_01611 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
CFDGDPAD_01612 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
CFDGDPAD_01613 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CFDGDPAD_01614 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFDGDPAD_01615 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
CFDGDPAD_01616 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CFDGDPAD_01617 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
CFDGDPAD_01618 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
CFDGDPAD_01619 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
CFDGDPAD_01620 4.6e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
CFDGDPAD_01621 2.85e-115 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
CFDGDPAD_01622 2.21e-87 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CFDGDPAD_01623 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFDGDPAD_01624 2.42e-204 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CFDGDPAD_01626 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
CFDGDPAD_01627 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
CFDGDPAD_01628 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
CFDGDPAD_01629 1.22e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CFDGDPAD_01630 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
CFDGDPAD_01631 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFDGDPAD_01632 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
CFDGDPAD_01633 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
CFDGDPAD_01634 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFDGDPAD_01635 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFDGDPAD_01636 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
CFDGDPAD_01637 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
CFDGDPAD_01638 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFDGDPAD_01639 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFDGDPAD_01640 2.89e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFDGDPAD_01641 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFDGDPAD_01642 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFDGDPAD_01643 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFDGDPAD_01644 3.89e-72 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
CFDGDPAD_01645 8.36e-113 ywmA - - - - - - -
CFDGDPAD_01646 7.55e-44 ywzB - - S - - - membrane
CFDGDPAD_01647 1.97e-173 ywmB - - S - - - TATA-box binding
CFDGDPAD_01648 1e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFDGDPAD_01649 2.8e-233 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
CFDGDPAD_01650 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
CFDGDPAD_01651 5.87e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
CFDGDPAD_01653 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CFDGDPAD_01654 5.35e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CFDGDPAD_01655 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
CFDGDPAD_01656 1.21e-109 ywmF - - S - - - Peptidase M50
CFDGDPAD_01657 1.84e-20 csbD - - K - - - CsbD-like
CFDGDPAD_01658 3.46e-05 urtA - - E ko:K11959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
CFDGDPAD_01659 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
CFDGDPAD_01660 3.2e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
CFDGDPAD_01661 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
CFDGDPAD_01662 4.58e-85 ywnA - - K - - - Transcriptional regulator
CFDGDPAD_01663 1.69e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
CFDGDPAD_01664 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
CFDGDPAD_01665 4.85e-184 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
CFDGDPAD_01666 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFDGDPAD_01667 1.43e-91 ywnF - - S - - - Family of unknown function (DUF5392)
CFDGDPAD_01668 4.73e-234 - - - M - - - NeuB family
CFDGDPAD_01669 2.32e-22 ywnC - - S - - - Family of unknown function (DUF5362)
CFDGDPAD_01670 5.19e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
CFDGDPAD_01671 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
CFDGDPAD_01672 3.84e-94 ywnJ - - S - - - VanZ like family
CFDGDPAD_01673 3.48e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
CFDGDPAD_01674 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
CFDGDPAD_01675 1.86e-287 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
CFDGDPAD_01676 1.69e-99 - - - - - - - -
CFDGDPAD_01677 1.48e-133 yjgF - - Q - - - Isochorismatase family
CFDGDPAD_01678 1.54e-306 ywoD - - EGP - - - Major facilitator superfamily
CFDGDPAD_01679 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
CFDGDPAD_01680 1.19e-311 ywoF - - P - - - Right handed beta helix region
CFDGDPAD_01682 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
CFDGDPAD_01683 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
CFDGDPAD_01684 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
CFDGDPAD_01685 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
CFDGDPAD_01686 4.16e-171 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
CFDGDPAD_01687 3.37e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
CFDGDPAD_01688 4.47e-256 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
CFDGDPAD_01689 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CFDGDPAD_01690 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CFDGDPAD_01691 0.0 ywpD - - T - - - Histidine kinase
CFDGDPAD_01692 1.18e-221 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
CFDGDPAD_01693 0.0 - - - M - - - cell wall anchor domain
CFDGDPAD_01694 1.01e-107 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
CFDGDPAD_01695 8.81e-89 ywpF - - S - - - YwpF-like protein
CFDGDPAD_01696 3.04e-87 ywpG - - - - - - -
CFDGDPAD_01697 8.53e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
CFDGDPAD_01698 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
CFDGDPAD_01699 8.76e-201 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
CFDGDPAD_01700 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
CFDGDPAD_01701 0.0 ywqB - - S - - - SWIM zinc finger
CFDGDPAD_01702 3.6e-25 - - - - - - - -
CFDGDPAD_01703 3.08e-162 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
CFDGDPAD_01704 1.22e-156 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
CFDGDPAD_01705 4.13e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
CFDGDPAD_01706 2.21e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFDGDPAD_01707 8.46e-196 ywqG - - S - - - Domain of unknown function (DUF1963)
CFDGDPAD_01709 1.04e-51 ywqI - - S - - - Family of unknown function (DUF5344)
CFDGDPAD_01710 2.04e-302 ywqJ - - S - - - Pre-toxin TG
CFDGDPAD_01712 7.19e-149 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
CFDGDPAD_01713 3.33e-209 - - - K - - - Transcriptional regulator
CFDGDPAD_01714 5.23e-130 ywqN - - S - - - NAD(P)H-dependent
CFDGDPAD_01716 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
CFDGDPAD_01717 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
CFDGDPAD_01718 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
CFDGDPAD_01719 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
CFDGDPAD_01720 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
CFDGDPAD_01721 4.35e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFDGDPAD_01722 2.17e-16 - - - - - - - -
CFDGDPAD_01723 4.57e-269 cotH - - M ko:K06330 - ko00000 Spore Coat
CFDGDPAD_01724 5.79e-182 cotB - - - ko:K06325 - ko00000 -
CFDGDPAD_01725 5.05e-161 ywrJ - - - - - - -
CFDGDPAD_01726 2.79e-280 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CFDGDPAD_01727 3.36e-218 alsR - - K - - - LysR substrate binding domain
CFDGDPAD_01728 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
CFDGDPAD_01729 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
CFDGDPAD_01730 3.57e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
CFDGDPAD_01731 9.2e-64 ywsA - - S - - - Protein of unknown function (DUF3892)
CFDGDPAD_01732 2.05e-121 batE - - T - - - Sh3 type 3 domain protein
CFDGDPAD_01733 1.56e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
CFDGDPAD_01734 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
CFDGDPAD_01735 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
CFDGDPAD_01736 9.31e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CFDGDPAD_01737 3.06e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CFDGDPAD_01738 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
CFDGDPAD_01739 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
CFDGDPAD_01740 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
CFDGDPAD_01741 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
CFDGDPAD_01742 2.29e-29 ywtC - - - - - - -
CFDGDPAD_01743 5.57e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CFDGDPAD_01744 1.46e-204 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
CFDGDPAD_01745 1.18e-176 ywtF_2 - - K - - - Transcriptional regulator
CFDGDPAD_01746 1.06e-313 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CFDGDPAD_01747 6.3e-273 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
CFDGDPAD_01748 1.76e-256 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
CFDGDPAD_01749 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
CFDGDPAD_01750 2.73e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
CFDGDPAD_01751 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CFDGDPAD_01752 6.65e-261 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CFDGDPAD_01753 5.03e-183 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CFDGDPAD_01754 2.81e-89 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
CFDGDPAD_01755 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CFDGDPAD_01756 0.0 tagF2 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CFDGDPAD_01758 6.48e-22 - - - M - - - transferase activity, transferring glycosyl groups
CFDGDPAD_01759 1.29e-172 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
CFDGDPAD_01760 2.7e-204 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CFDGDPAD_01761 1.07e-14 - - - L - - - COG2963 Transposase and inactivated derivatives
CFDGDPAD_01762 1.64e-204 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
CFDGDPAD_01763 4.03e-263 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CFDGDPAD_01764 4.48e-22 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
CFDGDPAD_01765 1.39e-15 - - - - - - - -
CFDGDPAD_01766 0.0 lytB - - D - - - Stage II sporulation protein
CFDGDPAD_01767 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
CFDGDPAD_01768 2.13e-150 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CFDGDPAD_01769 1.82e-300 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CFDGDPAD_01770 6.07e-257 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
CFDGDPAD_01771 2.01e-302 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFDGDPAD_01773 1.55e-315 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
CFDGDPAD_01774 2.8e-135 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
CFDGDPAD_01775 1.33e-174 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
CFDGDPAD_01776 1.38e-295 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
CFDGDPAD_01777 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
CFDGDPAD_01779 6.05e-100 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_01782 1.45e-50 - - - S - - - Psort location CytoplasmicMembrane, score
CFDGDPAD_01786 1.23e-151 - - - K - - - Transcriptional regulator
CFDGDPAD_01787 1.94e-136 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
CFDGDPAD_01788 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
CFDGDPAD_01789 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFDGDPAD_01790 2.15e-199 degV - - S - - - protein conserved in bacteria
CFDGDPAD_01791 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CFDGDPAD_01792 2.45e-59 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
CFDGDPAD_01793 2.26e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
CFDGDPAD_01794 1.83e-96 yvyF - - S - - - flagellar protein
CFDGDPAD_01795 5.05e-52 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
CFDGDPAD_01796 3.5e-102 yvyG - - NOU - - - FlgN protein
CFDGDPAD_01797 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
CFDGDPAD_01798 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
CFDGDPAD_01799 2.3e-90 yviE - - - - - - -
CFDGDPAD_01800 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CFDGDPAD_01801 1.05e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CFDGDPAD_01802 2.33e-160 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFDGDPAD_01803 3.03e-74 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
CFDGDPAD_01804 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CFDGDPAD_01805 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
CFDGDPAD_01806 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
CFDGDPAD_01807 1e-66 - - - - - - - -
CFDGDPAD_01808 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFDGDPAD_01809 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CFDGDPAD_01810 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CFDGDPAD_01811 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
CFDGDPAD_01812 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
CFDGDPAD_01813 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
CFDGDPAD_01814 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
CFDGDPAD_01815 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
CFDGDPAD_01816 1.38e-73 swrA - - S - - - Swarming motility protein
CFDGDPAD_01817 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFDGDPAD_01818 3.03e-295 yvkA - - P - - - -transporter
CFDGDPAD_01819 2.36e-130 yvkB - - K - - - Transcriptional regulator
CFDGDPAD_01820 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
CFDGDPAD_01821 2.54e-42 csbA - - S - - - protein conserved in bacteria
CFDGDPAD_01822 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CFDGDPAD_01823 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CFDGDPAD_01824 4.09e-156 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CFDGDPAD_01825 2.25e-45 yvkN - - - - - - -
CFDGDPAD_01826 8.09e-65 yvlA - - - - - - -
CFDGDPAD_01827 5.8e-221 yvlB - - S - - - Putative adhesin
CFDGDPAD_01828 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
CFDGDPAD_01829 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
CFDGDPAD_01830 6.75e-269 yvmA - - EGP - - - Major Facilitator Superfamily
CFDGDPAD_01831 1.03e-112 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
CFDGDPAD_01832 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
CFDGDPAD_01833 7.66e-292 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
CFDGDPAD_01834 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
CFDGDPAD_01835 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
CFDGDPAD_01836 4.12e-169 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
CFDGDPAD_01837 3.66e-167 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CFDGDPAD_01838 4.66e-277 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFDGDPAD_01839 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CFDGDPAD_01840 6.41e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CFDGDPAD_01841 1.84e-211 yvoD - - P - - - COG0370 Fe2 transport system protein B
CFDGDPAD_01842 1.06e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
CFDGDPAD_01843 5.29e-121 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
CFDGDPAD_01844 5.68e-156 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
CFDGDPAD_01845 2.49e-178 yvpB - - NU - - - protein conserved in bacteria
CFDGDPAD_01846 6.92e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CFDGDPAD_01847 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
CFDGDPAD_01848 1.81e-292 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFDGDPAD_01849 4.96e-139 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
CFDGDPAD_01850 3.43e-148 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFDGDPAD_01851 2.56e-164 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFDGDPAD_01852 3.26e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CFDGDPAD_01853 4.67e-144 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
CFDGDPAD_01854 1.01e-116 - - - S - - - Predicted membrane protein (DUF2339)
CFDGDPAD_01855 1.3e-88 - - - - - - - -
CFDGDPAD_01857 4.47e-86 - - - - - - - -
CFDGDPAD_01858 1.23e-109 - - - - - - - -
CFDGDPAD_01859 0.0 - - - - - - - -
CFDGDPAD_01861 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
CFDGDPAD_01862 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
CFDGDPAD_01863 1.08e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
CFDGDPAD_01864 1.18e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CFDGDPAD_01865 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
CFDGDPAD_01866 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
CFDGDPAD_01867 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
CFDGDPAD_01868 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
CFDGDPAD_01869 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
CFDGDPAD_01870 1.05e-178 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
CFDGDPAD_01871 1.37e-45 - - - - - - - -
CFDGDPAD_01872 1.83e-169 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDGDPAD_01873 4.61e-250 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
CFDGDPAD_01874 2.58e-180 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_01875 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
CFDGDPAD_01876 6.37e-232 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFDGDPAD_01877 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
CFDGDPAD_01878 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
CFDGDPAD_01879 3.2e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
CFDGDPAD_01880 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
CFDGDPAD_01881 1.54e-221 yvdE - - K - - - Transcriptional regulator
CFDGDPAD_01882 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
CFDGDPAD_01883 1.1e-297 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
CFDGDPAD_01884 8.65e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
CFDGDPAD_01885 2.79e-189 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
CFDGDPAD_01886 1.61e-196 malA - - S - - - Protein of unknown function (DUF1189)
CFDGDPAD_01887 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
CFDGDPAD_01888 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
CFDGDPAD_01889 1.74e-152 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
CFDGDPAD_01890 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CFDGDPAD_01892 9.45e-234 - - - S - - - Patatin-like phospholipase
CFDGDPAD_01893 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
CFDGDPAD_01894 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
CFDGDPAD_01895 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
CFDGDPAD_01896 6.31e-68 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
CFDGDPAD_01897 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
CFDGDPAD_01898 0.0 ybeC - - E - - - amino acid
CFDGDPAD_01899 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
CFDGDPAD_01900 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
CFDGDPAD_01901 0.0 pbpE - - V - - - Beta-lactamase
CFDGDPAD_01902 2.06e-161 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
CFDGDPAD_01903 1.11e-49 - - - S - - - Protein of unknown function (DUF3237)
CFDGDPAD_01904 1.81e-118 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
CFDGDPAD_01906 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
CFDGDPAD_01907 1.24e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
CFDGDPAD_01908 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
CFDGDPAD_01909 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
CFDGDPAD_01910 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
CFDGDPAD_01911 4.02e-284 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
CFDGDPAD_01912 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
CFDGDPAD_01913 5.65e-275 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
CFDGDPAD_01914 3.59e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
CFDGDPAD_01915 1.22e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
CFDGDPAD_01916 9.86e-262 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
CFDGDPAD_01917 2.46e-248 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
CFDGDPAD_01918 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CFDGDPAD_01919 1.11e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CFDGDPAD_01920 2.03e-77 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
CFDGDPAD_01921 2.14e-278 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
CFDGDPAD_01922 7.24e-239 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
CFDGDPAD_01923 5.69e-44 yvfG - - S - - - YvfG protein
CFDGDPAD_01924 6.75e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
CFDGDPAD_01925 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
CFDGDPAD_01926 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
CFDGDPAD_01927 1.51e-235 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_01928 7.78e-286 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
CFDGDPAD_01929 2.15e-300 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
CFDGDPAD_01930 1.1e-193 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
CFDGDPAD_01931 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
CFDGDPAD_01932 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
CFDGDPAD_01933 6.3e-258 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
CFDGDPAD_01934 7.25e-201 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
CFDGDPAD_01935 5.95e-209 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
CFDGDPAD_01936 2.48e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
CFDGDPAD_01937 1.88e-252 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFDGDPAD_01938 4.36e-136 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFDGDPAD_01939 5.47e-176 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CFDGDPAD_01940 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
CFDGDPAD_01941 1.45e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CFDGDPAD_01942 2.68e-252 - - - S - - - Glycosyl hydrolase
CFDGDPAD_01943 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
CFDGDPAD_01944 3.93e-198 yvbV - - EG - - - EamA-like transporter family
CFDGDPAD_01945 4.9e-206 yvbU - - K - - - Transcriptional regulator
CFDGDPAD_01946 2.45e-244 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFDGDPAD_01947 5.04e-257 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
CFDGDPAD_01948 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CFDGDPAD_01949 5.69e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CFDGDPAD_01950 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CFDGDPAD_01951 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
CFDGDPAD_01952 6.09e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CFDGDPAD_01953 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
CFDGDPAD_01954 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CFDGDPAD_01956 6.59e-10 - - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFDGDPAD_01957 4.6e-29 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CFDGDPAD_01958 9.87e-142 - 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CFDGDPAD_01959 5.55e-12 - 2.3.1.179 - IQ ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 synthase
CFDGDPAD_01960 2.04e-75 - 1.1.1.100 - IQ ko:K00059,ko:K07535 ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
CFDGDPAD_01963 6.09e-100 yvbK - - K - - - acetyltransferase
CFDGDPAD_01964 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
CFDGDPAD_01965 3.24e-156 yvbI - - M - - - Membrane
CFDGDPAD_01966 2.96e-145 yvbH - - S - - - YvbH-like oligomerisation region
CFDGDPAD_01967 1.13e-134 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
CFDGDPAD_01968 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
CFDGDPAD_01969 3.76e-268 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CFDGDPAD_01970 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
CFDGDPAD_01971 2.58e-223 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CFDGDPAD_01972 9.67e-137 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
CFDGDPAD_01973 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
CFDGDPAD_01974 2.02e-268 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CFDGDPAD_01975 2.2e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
CFDGDPAD_01976 7.93e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CFDGDPAD_01977 2.26e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
CFDGDPAD_01978 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CFDGDPAD_01979 3.85e-72 yvaP - - K - - - transcriptional
CFDGDPAD_01980 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
CFDGDPAD_01981 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
CFDGDPAD_01982 3.44e-48 yvzC - - K - - - transcriptional
CFDGDPAD_01983 6.64e-192 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
CFDGDPAD_01984 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
CFDGDPAD_01985 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
CFDGDPAD_01986 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CFDGDPAD_01987 1.97e-106 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CFDGDPAD_01989 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDGDPAD_01990 8.55e-129 - - - K - - - Bacterial regulatory proteins, tetR family
CFDGDPAD_01991 3.39e-69 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
CFDGDPAD_01992 8.22e-97 yvaD - - S - - - Family of unknown function (DUF5360)
CFDGDPAD_01993 0.0 - - - S - - - Fusaric acid resistance protein-like
CFDGDPAD_01994 5.95e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFDGDPAD_01995 1.64e-246 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
CFDGDPAD_01996 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
CFDGDPAD_01997 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
CFDGDPAD_01998 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
CFDGDPAD_01999 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
CFDGDPAD_02000 3.45e-137 bdbD - - O - - - Thioredoxin
CFDGDPAD_02001 1.64e-94 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
CFDGDPAD_02002 2.34e-139 yvgT - - S - - - membrane
CFDGDPAD_02004 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
CFDGDPAD_02005 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CFDGDPAD_02006 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
CFDGDPAD_02007 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
CFDGDPAD_02008 7.97e-113 yvgO - - - - - - -
CFDGDPAD_02009 2.63e-202 yvgN - - S - - - reductase
CFDGDPAD_02010 4.79e-151 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
CFDGDPAD_02011 1.8e-176 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
CFDGDPAD_02012 2.54e-214 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
CFDGDPAD_02013 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
CFDGDPAD_02014 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
CFDGDPAD_02015 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
CFDGDPAD_02016 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
CFDGDPAD_02017 5.19e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CFDGDPAD_02018 1.72e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDGDPAD_02019 3.22e-224 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDGDPAD_02020 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
CFDGDPAD_02021 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
CFDGDPAD_02022 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_02023 3.36e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
CFDGDPAD_02024 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
CFDGDPAD_02025 6.23e-290 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
CFDGDPAD_02026 3.46e-26 - - - S - - - YvrJ protein family
CFDGDPAD_02027 5.77e-127 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
CFDGDPAD_02028 7.2e-32 - - - - - - - -
CFDGDPAD_02029 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDGDPAD_02030 0.0 yvrG - - T - - - Histidine kinase
CFDGDPAD_02031 7.64e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
CFDGDPAD_02032 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDGDPAD_02033 1.58e-213 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
CFDGDPAD_02034 2.22e-235 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDGDPAD_02035 7.39e-309 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
CFDGDPAD_02036 6.75e-132 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
CFDGDPAD_02037 3.76e-287 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
CFDGDPAD_02038 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
CFDGDPAD_02039 9.94e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
CFDGDPAD_02040 2.19e-176 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
CFDGDPAD_02041 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
CFDGDPAD_02042 1.16e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFDGDPAD_02043 2.69e-140 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFDGDPAD_02044 2.4e-240 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
CFDGDPAD_02045 9.69e-252 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
CFDGDPAD_02046 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
CFDGDPAD_02047 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
CFDGDPAD_02048 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CFDGDPAD_02049 3.06e-204 yuxN - - K - - - Transcriptional regulator
CFDGDPAD_02050 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFDGDPAD_02051 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDGDPAD_02052 9.21e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CFDGDPAD_02053 1.07e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
CFDGDPAD_02054 1.29e-195 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDGDPAD_02055 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
CFDGDPAD_02056 2.01e-87 - - - S - - - YusW-like protein
CFDGDPAD_02057 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
CFDGDPAD_02058 3.99e-53 yusU - - S - - - Protein of unknown function (DUF2573)
CFDGDPAD_02059 8.42e-204 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
CFDGDPAD_02060 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDGDPAD_02061 1.7e-84 yusQ - - S - - - Tautomerase enzyme
CFDGDPAD_02062 0.0 yusP - - P - - - Major facilitator superfamily
CFDGDPAD_02063 4.47e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
CFDGDPAD_02064 2.12e-70 yusN - - M - - - Coat F domain
CFDGDPAD_02065 2.23e-54 - - - - - - - -
CFDGDPAD_02066 2.09e-212 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
CFDGDPAD_02067 1.11e-13 - - - S - - - YuzL-like protein
CFDGDPAD_02068 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
CFDGDPAD_02069 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
CFDGDPAD_02070 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
CFDGDPAD_02071 8.34e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
CFDGDPAD_02072 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
CFDGDPAD_02073 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
CFDGDPAD_02074 2.66e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
CFDGDPAD_02075 2e-73 yusE - - CO - - - Thioredoxin
CFDGDPAD_02076 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
CFDGDPAD_02077 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFDGDPAD_02078 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
CFDGDPAD_02079 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
CFDGDPAD_02080 3.15e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFDGDPAD_02081 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
CFDGDPAD_02082 7.43e-313 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
CFDGDPAD_02083 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFDGDPAD_02084 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
CFDGDPAD_02085 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
CFDGDPAD_02086 1.43e-69 - - - S - - - MazG-like family
CFDGDPAD_02087 0.0 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
CFDGDPAD_02088 3.35e-56 - - - - - - - -
CFDGDPAD_02090 1.36e-266 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
CFDGDPAD_02091 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
CFDGDPAD_02092 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
CFDGDPAD_02093 3.35e-306 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
CFDGDPAD_02094 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CFDGDPAD_02095 4.58e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
CFDGDPAD_02096 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
CFDGDPAD_02097 7.46e-176 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
CFDGDPAD_02098 9.87e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
CFDGDPAD_02099 6.53e-218 bsn - - L - - - Ribonuclease
CFDGDPAD_02100 4.9e-303 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
CFDGDPAD_02101 8.51e-306 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
CFDGDPAD_02103 1.06e-235 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CFDGDPAD_02104 4.88e-140 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
CFDGDPAD_02105 5.2e-189 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
CFDGDPAD_02106 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
CFDGDPAD_02107 1.7e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
CFDGDPAD_02108 1.47e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
CFDGDPAD_02109 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
CFDGDPAD_02110 1.11e-283 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
CFDGDPAD_02111 6.93e-299 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
CFDGDPAD_02112 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
CFDGDPAD_02113 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
CFDGDPAD_02114 1.07e-79 yunG - - - - - - -
CFDGDPAD_02115 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
CFDGDPAD_02116 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
CFDGDPAD_02117 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
CFDGDPAD_02118 1.39e-64 yunC - - S - - - Domain of unknown function (DUF1805)
CFDGDPAD_02119 1.42e-168 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
CFDGDPAD_02120 6.28e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
CFDGDPAD_02121 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CFDGDPAD_02122 7.77e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CFDGDPAD_02123 3.2e-63 yutD - - S - - - protein conserved in bacteria
CFDGDPAD_02124 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
CFDGDPAD_02125 3.69e-183 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CFDGDPAD_02126 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
CFDGDPAD_02127 1.17e-250 yutH - - S - - - Spore coat protein
CFDGDPAD_02128 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
CFDGDPAD_02129 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CFDGDPAD_02130 1.04e-220 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CFDGDPAD_02131 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
CFDGDPAD_02132 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
CFDGDPAD_02133 6.61e-75 yuzD - - S - - - protein conserved in bacteria
CFDGDPAD_02134 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
CFDGDPAD_02135 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
CFDGDPAD_02136 2.54e-269 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CFDGDPAD_02137 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CFDGDPAD_02138 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
CFDGDPAD_02139 3.28e-114 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFDGDPAD_02140 9.91e-150 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
CFDGDPAD_02141 1.84e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CFDGDPAD_02143 1.92e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
CFDGDPAD_02144 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
CFDGDPAD_02145 9.78e-47 yuiB - - S - - - Putative membrane protein
CFDGDPAD_02146 1.39e-150 yuiC - - S - - - protein conserved in bacteria
CFDGDPAD_02147 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
CFDGDPAD_02148 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CFDGDPAD_02149 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
CFDGDPAD_02150 1.38e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
CFDGDPAD_02151 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
CFDGDPAD_02152 7.35e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
CFDGDPAD_02153 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDGDPAD_02154 7.34e-291 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
CFDGDPAD_02155 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
CFDGDPAD_02156 3.83e-229 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
CFDGDPAD_02157 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDGDPAD_02158 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
CFDGDPAD_02159 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
CFDGDPAD_02160 1.64e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
CFDGDPAD_02161 1.03e-292 yukF - - QT - - - Transcriptional regulator
CFDGDPAD_02162 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
CFDGDPAD_02163 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
CFDGDPAD_02164 4.08e-269 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
CFDGDPAD_02165 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
CFDGDPAD_02166 0.0 yueB - - S - - - type VII secretion protein EsaA
CFDGDPAD_02167 5.1e-96 yueC - - S - - - Family of unknown function (DUF5383)
CFDGDPAD_02168 1.18e-168 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDGDPAD_02169 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
CFDGDPAD_02170 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
CFDGDPAD_02171 9.01e-90 - - - S - - - Protein of unknown function (DUF2283)
CFDGDPAD_02172 2.24e-243 yueF - - S - - - transporter activity
CFDGDPAD_02173 1.23e-43 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
CFDGDPAD_02174 1.63e-52 yueH - - S - - - YueH-like protein
CFDGDPAD_02175 8.92e-87 - - - S - - - Protein of unknown function (DUF1694)
CFDGDPAD_02176 3.27e-134 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
CFDGDPAD_02177 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFDGDPAD_02178 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
CFDGDPAD_02179 8.73e-09 yuzC - - - - - - -
CFDGDPAD_02180 6.29e-10 - - - S - - - DegQ (SacQ) family
CFDGDPAD_02181 3.3e-208 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
CFDGDPAD_02183 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFDGDPAD_02184 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFDGDPAD_02185 7.81e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
CFDGDPAD_02186 5.97e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
CFDGDPAD_02187 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CFDGDPAD_02188 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CFDGDPAD_02189 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CFDGDPAD_02190 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CFDGDPAD_02191 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CFDGDPAD_02192 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
CFDGDPAD_02193 1.17e-20 - - - - - - - -
CFDGDPAD_02194 1.61e-308 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
CFDGDPAD_02195 2.43e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
CFDGDPAD_02196 9.08e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
CFDGDPAD_02197 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_02198 2.12e-252 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
CFDGDPAD_02199 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
CFDGDPAD_02200 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
CFDGDPAD_02201 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
CFDGDPAD_02202 1.35e-97 yuxK - - S - - - protein conserved in bacteria
CFDGDPAD_02203 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
CFDGDPAD_02204 1.54e-242 yuxJ - - EGP - - - Major facilitator superfamily
CFDGDPAD_02206 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
CFDGDPAD_02207 7.15e-91 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
CFDGDPAD_02208 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFDGDPAD_02209 1.11e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
CFDGDPAD_02210 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
CFDGDPAD_02211 9.89e-201 yugF - - I - - - Hydrolase
CFDGDPAD_02212 6.74e-112 alaR - - K - - - Transcriptional regulator
CFDGDPAD_02213 2.21e-254 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
CFDGDPAD_02214 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
CFDGDPAD_02215 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
CFDGDPAD_02216 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
CFDGDPAD_02217 2.64e-289 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
CFDGDPAD_02218 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
CFDGDPAD_02220 4.22e-95 yugN - - S - - - YugN-like family
CFDGDPAD_02221 2.92e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
CFDGDPAD_02222 2.48e-69 mstX - - S - - - Membrane-integrating protein Mistic
CFDGDPAD_02223 2.16e-48 - - - - - - - -
CFDGDPAD_02224 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
CFDGDPAD_02225 2.52e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
CFDGDPAD_02226 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
CFDGDPAD_02227 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
CFDGDPAD_02228 5e-48 - - - - - - - -
CFDGDPAD_02229 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
CFDGDPAD_02230 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CFDGDPAD_02231 9.82e-297 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CFDGDPAD_02232 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CFDGDPAD_02233 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CFDGDPAD_02234 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
CFDGDPAD_02235 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
CFDGDPAD_02236 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
CFDGDPAD_02237 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
CFDGDPAD_02238 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
CFDGDPAD_02239 2.61e-235 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
CFDGDPAD_02240 1.73e-252 yubA - - S - - - transporter activity
CFDGDPAD_02241 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CFDGDPAD_02243 3.95e-113 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
CFDGDPAD_02244 0.0 yubD - - P - - - Major Facilitator Superfamily
CFDGDPAD_02245 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CFDGDPAD_02246 3.31e-52 yubF - - S - - - yiaA/B two helix domain
CFDGDPAD_02247 4.35e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
CFDGDPAD_02248 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
CFDGDPAD_02249 5.83e-118 yuaB - - - - - - -
CFDGDPAD_02250 2.39e-121 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
CFDGDPAD_02251 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
CFDGDPAD_02252 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
CFDGDPAD_02253 3.5e-138 yuaD - - - - - - -
CFDGDPAD_02254 1.95e-109 yuaE - - S - - - DinB superfamily
CFDGDPAD_02255 4.82e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
CFDGDPAD_02256 2.61e-257 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
CFDGDPAD_02257 9.48e-120 - - - M - - - FR47-like protein
CFDGDPAD_02258 3.58e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
CFDGDPAD_02259 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
CFDGDPAD_02260 1.92e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
CFDGDPAD_02261 9.8e-313 yoeA - - V - - - MATE efflux family protein
CFDGDPAD_02262 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
CFDGDPAD_02264 1.14e-124 - - - L - - - Integrase
CFDGDPAD_02265 9.51e-47 yoeD - - G - - - Helix-turn-helix domain
CFDGDPAD_02266 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
CFDGDPAD_02267 1.3e-202 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_02268 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
CFDGDPAD_02269 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
CFDGDPAD_02270 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
CFDGDPAD_02271 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_02272 3.86e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFDGDPAD_02273 2.72e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CFDGDPAD_02274 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
CFDGDPAD_02275 6.25e-157 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDGDPAD_02276 9.05e-52 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
CFDGDPAD_02277 2.4e-162 yoxB - - - - - - -
CFDGDPAD_02278 3.96e-114 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CFDGDPAD_02279 6.87e-300 - - - S - - - Arylsulfotransferase (ASST)
CFDGDPAD_02280 2.75e-160 - 3.1.1.3 - I ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 Lipase (class 3)
CFDGDPAD_02281 4.51e-300 yoaB - - EGP - - - the major facilitator superfamily
CFDGDPAD_02282 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
CFDGDPAD_02283 1.43e-235 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFDGDPAD_02284 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CFDGDPAD_02285 7.24e-45 yoaF - - - - - - -
CFDGDPAD_02287 1.25e-20 - - - - - - - -
CFDGDPAD_02288 1.13e-59 - - - S - - - Protein of unknown function (DUF4025)
CFDGDPAD_02289 3.08e-308 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
CFDGDPAD_02290 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
CFDGDPAD_02291 1.76e-169 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
CFDGDPAD_02292 1.79e-145 yoaK - - S - - - Membrane
CFDGDPAD_02293 5e-253 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
CFDGDPAD_02294 3.3e-167 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
CFDGDPAD_02297 8.53e-291 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
CFDGDPAD_02299 2.14e-184 yoaP - - K - - - YoaP-like
CFDGDPAD_02300 1.49e-87 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
CFDGDPAD_02302 4.87e-91 - - - - - - - -
CFDGDPAD_02303 4.24e-217 yoaR - - V - - - vancomycin resistance protein
CFDGDPAD_02304 2.65e-97 yoaS - - S - - - Protein of unknown function (DUF2975)
CFDGDPAD_02305 7.19e-41 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_02306 6.64e-190 yoaT - - S - - - Protein of unknown function (DUF817)
CFDGDPAD_02307 1.29e-200 yoaU - - K - - - LysR substrate binding domain
CFDGDPAD_02308 3.7e-201 yoaV - - EG - - - EamA-like transporter family
CFDGDPAD_02309 3.26e-101 yoaW - - - - - - -
CFDGDPAD_02310 1.91e-144 lin0465 - - S - - - DJ-1/PfpI family
CFDGDPAD_02311 2e-212 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
CFDGDPAD_02314 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
CFDGDPAD_02315 7.53e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
CFDGDPAD_02316 6.27e-51 - - - S - - - TM2 domain
CFDGDPAD_02317 2.26e-63 - - - K - - - Helix-turn-helix
CFDGDPAD_02319 1.45e-38 - - - - - - - -
CFDGDPAD_02324 2.19e-72 - - - J - - - tRNA cytidylyltransferase activity
CFDGDPAD_02325 1.16e-55 - - - - - - - -
CFDGDPAD_02326 1.49e-09 ywlA - - S - - - Uncharacterised protein family (UPF0715)
CFDGDPAD_02328 5.18e-99 - - - - - - - -
CFDGDPAD_02329 1.48e-82 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
CFDGDPAD_02330 3.29e-161 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
CFDGDPAD_02331 3.65e-224 - - - - - - - -
CFDGDPAD_02332 3.35e-11 - - - - - - - -
CFDGDPAD_02337 9.08e-134 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
CFDGDPAD_02339 1.95e-26 - - - - - - - -
CFDGDPAD_02340 2.56e-43 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFDGDPAD_02341 2.01e-109 - - - S - - - damaged DNA binding
CFDGDPAD_02342 1.58e-25 - - - S - - - YolD-like protein
CFDGDPAD_02344 1.76e-126 - - - J - - - Acetyltransferase (GNAT) domain
CFDGDPAD_02345 1.37e-56 yokK - - S - - - SMI1 / KNR4 family
CFDGDPAD_02346 3.61e-61 yokK - - S - - - SMI1 / KNR4 family
CFDGDPAD_02347 3.88e-64 - - - S - - - SMI1-KNR4 cell-wall
CFDGDPAD_02348 4.97e-25 - - - S - - - SMI1-KNR4 cell-wall
CFDGDPAD_02349 2.24e-110 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
CFDGDPAD_02350 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CFDGDPAD_02351 1.14e-131 yokH - - G - - - SMI1 / KNR4 family
CFDGDPAD_02352 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
CFDGDPAD_02353 1.49e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
CFDGDPAD_02354 6.36e-172 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
CFDGDPAD_02355 4.16e-180 - - - J - - - FR47-like protein
CFDGDPAD_02356 4.91e-124 yobS - - K - - - Transcriptional regulator
CFDGDPAD_02357 2.22e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
CFDGDPAD_02358 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
CFDGDPAD_02359 9.35e-226 yobV - - K - - - WYL domain
CFDGDPAD_02360 3.01e-120 yobW - - - - - - -
CFDGDPAD_02361 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
CFDGDPAD_02362 2.12e-155 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CFDGDPAD_02363 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
CFDGDPAD_02364 2.91e-182 - - - - - - - -
CFDGDPAD_02365 2.55e-120 yocC - - - - - - -
CFDGDPAD_02366 8.17e-242 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
CFDGDPAD_02367 3.28e-257 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
CFDGDPAD_02368 3.51e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFDGDPAD_02369 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFDGDPAD_02370 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
CFDGDPAD_02371 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
CFDGDPAD_02372 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CFDGDPAD_02373 2.02e-107 yocK - - T - - - general stress protein
CFDGDPAD_02374 4.13e-68 yocL - - - - - - -
CFDGDPAD_02375 3.93e-41 - - - - - - - -
CFDGDPAD_02376 1.56e-113 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
CFDGDPAD_02377 2.94e-55 yozN - - - - - - -
CFDGDPAD_02378 1.83e-49 yocN - - - - - - -
CFDGDPAD_02379 2.17e-74 yozO - - S - - - Bacterial PH domain
CFDGDPAD_02380 1.91e-42 yozC - - - - - - -
CFDGDPAD_02381 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
CFDGDPAD_02382 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
CFDGDPAD_02383 2.26e-210 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
CFDGDPAD_02384 6.18e-300 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CFDGDPAD_02385 2.52e-205 yocS - - S ko:K03453 - ko00000 -transporter
CFDGDPAD_02386 2.59e-264 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
CFDGDPAD_02387 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
CFDGDPAD_02388 0.0 yojO - - P - - - Von Willebrand factor
CFDGDPAD_02389 7.7e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
CFDGDPAD_02390 6.01e-141 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CFDGDPAD_02391 1.23e-262 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
CFDGDPAD_02392 5.62e-294 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
CFDGDPAD_02393 4.31e-141 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CFDGDPAD_02395 2.93e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
CFDGDPAD_02396 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CFDGDPAD_02397 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
CFDGDPAD_02398 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
CFDGDPAD_02399 1.85e-58 - - - - - - - -
CFDGDPAD_02400 8.13e-208 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
CFDGDPAD_02401 3.03e-106 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
CFDGDPAD_02402 5.59e-14 - - - - - - - -
CFDGDPAD_02403 3.23e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
CFDGDPAD_02404 5.64e-84 iolK - - S - - - tautomerase
CFDGDPAD_02405 2.63e-73 yodB - - K - - - transcriptional
CFDGDPAD_02406 1.11e-139 yodC - - C - - - nitroreductase
CFDGDPAD_02407 1.31e-146 yahD - - S ko:K06999 - ko00000 Carboxylesterase
CFDGDPAD_02408 4.61e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
CFDGDPAD_02409 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
CFDGDPAD_02410 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFDGDPAD_02411 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
CFDGDPAD_02412 3.03e-166 yodH - - Q - - - Methyltransferase
CFDGDPAD_02413 2.93e-42 yodI - - - - - - -
CFDGDPAD_02414 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
CFDGDPAD_02415 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
CFDGDPAD_02416 2.08e-12 - - - - - - - -
CFDGDPAD_02417 1.17e-71 yodL - - S - - - YodL-like
CFDGDPAD_02418 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
CFDGDPAD_02419 5.18e-34 yozD - - S - - - YozD-like protein
CFDGDPAD_02421 1.29e-159 yodN - - - - - - -
CFDGDPAD_02422 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
CFDGDPAD_02423 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
CFDGDPAD_02424 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
CFDGDPAD_02425 1.51e-196 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
CFDGDPAD_02426 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
CFDGDPAD_02427 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CFDGDPAD_02428 2.8e-160 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CFDGDPAD_02429 9.36e-317 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFDGDPAD_02431 3.67e-180 yiiD - - K ko:K06323 - ko00000 acetyltransferase
CFDGDPAD_02432 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
CFDGDPAD_02433 6.14e-59 cgeC - - - ko:K06321 - ko00000 -
CFDGDPAD_02434 5.35e-84 cgeA - - - ko:K06319 - ko00000 -
CFDGDPAD_02435 1.2e-239 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
CFDGDPAD_02436 7.73e-278 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
CFDGDPAD_02437 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
CFDGDPAD_02438 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
CFDGDPAD_02439 3.85e-132 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFDGDPAD_02440 4.14e-94 ypoP - - K - - - transcriptional
CFDGDPAD_02441 4.95e-290 mepA - - V - - - MATE efflux family protein
CFDGDPAD_02442 2.13e-40 ypmT - - S - - - Uncharacterized ympT
CFDGDPAD_02443 6.8e-129 ypmS - - S - - - protein conserved in bacteria
CFDGDPAD_02444 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
CFDGDPAD_02445 3.23e-139 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
CFDGDPAD_02446 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
CFDGDPAD_02447 2.46e-308 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFDGDPAD_02448 2.32e-235 yplP - - K - - - Transcriptional regulator
CFDGDPAD_02449 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
CFDGDPAD_02450 8.12e-144 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CFDGDPAD_02451 4.75e-122 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CFDGDPAD_02452 2.43e-201 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CFDGDPAD_02453 2.56e-120 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
CFDGDPAD_02454 1.16e-146 ypjP - - S - - - YpjP-like protein
CFDGDPAD_02455 4.15e-185 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
CFDGDPAD_02456 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
CFDGDPAD_02457 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
CFDGDPAD_02458 2e-204 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
CFDGDPAD_02459 6.65e-138 yagB - - S ko:K06950 - ko00000 phosphohydrolase
CFDGDPAD_02460 3.13e-114 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
CFDGDPAD_02461 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFDGDPAD_02463 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
CFDGDPAD_02464 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
CFDGDPAD_02465 1.17e-22 degR - - - - - - -
CFDGDPAD_02466 1.5e-40 - - - S - - - Protein of unknown function (DUF2564)
CFDGDPAD_02467 7.99e-41 ypeQ - - S - - - Zinc-finger
CFDGDPAD_02468 1.1e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
CFDGDPAD_02469 3.98e-137 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CFDGDPAD_02470 5.37e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
CFDGDPAD_02471 5.23e-05 - - - - ko:K06429 - ko00000 -
CFDGDPAD_02472 1.31e-212 ypcP - - L - - - 5'3' exonuclease
CFDGDPAD_02473 1.08e-11 - - - - - - - -
CFDGDPAD_02474 1.17e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
CFDGDPAD_02475 0.0 ypbR - - S - - - Dynamin family
CFDGDPAD_02476 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
CFDGDPAD_02477 1.85e-265 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
CFDGDPAD_02478 3.14e-294 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
CFDGDPAD_02479 2.34e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CFDGDPAD_02480 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CFDGDPAD_02481 2.88e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
CFDGDPAD_02482 1.03e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
CFDGDPAD_02483 6.95e-238 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
CFDGDPAD_02484 1.19e-234 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
CFDGDPAD_02485 4.2e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CFDGDPAD_02486 1.68e-178 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDGDPAD_02487 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
CFDGDPAD_02489 1.16e-285 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
CFDGDPAD_02490 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CFDGDPAD_02491 3.41e-128 ypsA - - S - - - Belongs to the UPF0398 family
CFDGDPAD_02492 5.68e-298 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
CFDGDPAD_02493 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
CFDGDPAD_02494 5.3e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
CFDGDPAD_02495 1.76e-94 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
CFDGDPAD_02496 8.72e-68 yppG - - S - - - YppG-like protein
CFDGDPAD_02497 9.21e-11 - - - S - - - YppF-like protein
CFDGDPAD_02498 1.42e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
CFDGDPAD_02501 4.54e-241 yppC - - S - - - Protein of unknown function (DUF2515)
CFDGDPAD_02502 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CFDGDPAD_02503 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
CFDGDPAD_02504 4.09e-121 ypoC - - - - - - -
CFDGDPAD_02505 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CFDGDPAD_02506 3.83e-164 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
CFDGDPAD_02507 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
CFDGDPAD_02508 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
CFDGDPAD_02509 2.27e-103 ypmB - - S - - - protein conserved in bacteria
CFDGDPAD_02510 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
CFDGDPAD_02511 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
CFDGDPAD_02512 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CFDGDPAD_02513 5.47e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CFDGDPAD_02514 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
CFDGDPAD_02515 1.63e-232 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CFDGDPAD_02516 1.41e-283 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CFDGDPAD_02517 8.54e-268 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
CFDGDPAD_02518 3.82e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
CFDGDPAD_02519 1.52e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
CFDGDPAD_02520 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CFDGDPAD_02521 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
CFDGDPAD_02522 7.46e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
CFDGDPAD_02523 6.84e-183 ypjB - - S - - - sporulation protein
CFDGDPAD_02524 2.82e-126 ypjA - - S - - - membrane
CFDGDPAD_02525 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
CFDGDPAD_02526 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
CFDGDPAD_02527 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
CFDGDPAD_02528 1.86e-98 ypiF - - S - - - Protein of unknown function (DUF2487)
CFDGDPAD_02529 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
CFDGDPAD_02530 3.56e-297 ypiA - - S - - - COG0457 FOG TPR repeat
CFDGDPAD_02531 9.91e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CFDGDPAD_02532 1.71e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
CFDGDPAD_02533 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFDGDPAD_02534 3.66e-184 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CFDGDPAD_02535 3.8e-294 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CFDGDPAD_02536 2.71e-151 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
CFDGDPAD_02537 2.07e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
CFDGDPAD_02538 6.08e-230 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFDGDPAD_02539 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFDGDPAD_02540 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
CFDGDPAD_02541 4.7e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFDGDPAD_02542 2.91e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CFDGDPAD_02543 3.69e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
CFDGDPAD_02544 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
CFDGDPAD_02545 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
CFDGDPAD_02546 5.46e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CFDGDPAD_02547 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
CFDGDPAD_02548 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
CFDGDPAD_02549 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
CFDGDPAD_02550 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CFDGDPAD_02551 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CFDGDPAD_02552 8.71e-176 yphF - - - - - - -
CFDGDPAD_02553 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
CFDGDPAD_02554 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
CFDGDPAD_02555 1.72e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
CFDGDPAD_02556 8.69e-40 ypzH - - - - - - -
CFDGDPAD_02557 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
CFDGDPAD_02558 3.87e-134 yphA - - - - - - -
CFDGDPAD_02559 1.13e-11 - - - S - - - YpzI-like protein
CFDGDPAD_02560 8.06e-236 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CFDGDPAD_02561 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
CFDGDPAD_02562 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
CFDGDPAD_02563 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
CFDGDPAD_02564 1.09e-142 ypfA - - M - - - Flagellar protein YcgR
CFDGDPAD_02565 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
CFDGDPAD_02566 1.4e-207 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
CFDGDPAD_02567 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
CFDGDPAD_02568 2.57e-224 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
CFDGDPAD_02569 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
CFDGDPAD_02570 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CFDGDPAD_02571 1.02e-186 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
CFDGDPAD_02572 5.79e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
CFDGDPAD_02573 8.61e-143 ypbE - - M - - - Lysin motif
CFDGDPAD_02574 4.14e-127 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
CFDGDPAD_02575 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
CFDGDPAD_02576 4.66e-257 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
CFDGDPAD_02577 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
CFDGDPAD_02578 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CFDGDPAD_02579 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFDGDPAD_02580 1.95e-173 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CFDGDPAD_02581 2.27e-249 rsiX - - - - - - -
CFDGDPAD_02582 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CFDGDPAD_02583 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFDGDPAD_02584 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDGDPAD_02585 1.34e-278 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
CFDGDPAD_02586 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
CFDGDPAD_02587 8.71e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
CFDGDPAD_02588 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
CFDGDPAD_02589 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
CFDGDPAD_02590 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
CFDGDPAD_02591 4.11e-273 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
CFDGDPAD_02592 6.13e-128 ypuI - - S - - - Protein of unknown function (DUF3907)
CFDGDPAD_02593 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFDGDPAD_02594 1.55e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFDGDPAD_02595 1.02e-119 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
CFDGDPAD_02596 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFDGDPAD_02597 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CFDGDPAD_02598 2.1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CFDGDPAD_02599 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
CFDGDPAD_02600 2.07e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CFDGDPAD_02601 5.98e-72 ypuD - - - - - - -
CFDGDPAD_02602 4.1e-126 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
CFDGDPAD_02603 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
CFDGDPAD_02604 1.36e-35 - - - S - - - SNARE associated Golgi protein
CFDGDPAD_02607 2.61e-34 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CFDGDPAD_02612 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CFDGDPAD_02613 1.8e-191 ypuA - - S - - - Secreted protein
CFDGDPAD_02614 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CFDGDPAD_02615 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
CFDGDPAD_02616 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
CFDGDPAD_02617 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
CFDGDPAD_02618 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
CFDGDPAD_02619 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
CFDGDPAD_02620 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
CFDGDPAD_02621 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
CFDGDPAD_02622 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFDGDPAD_02623 1.37e-99 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
CFDGDPAD_02624 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
CFDGDPAD_02625 7.93e-270 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
CFDGDPAD_02626 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CFDGDPAD_02627 6.8e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
CFDGDPAD_02628 1.12e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
CFDGDPAD_02629 2.25e-49 - - - S - - - Protein of unknown function (DUF4227)
CFDGDPAD_02630 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
CFDGDPAD_02631 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
CFDGDPAD_02632 2.34e-40 yqkK - - - - - - -
CFDGDPAD_02633 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
CFDGDPAD_02634 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
CFDGDPAD_02635 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
CFDGDPAD_02636 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
CFDGDPAD_02637 3.18e-77 ansR - - K - - - Transcriptional regulator
CFDGDPAD_02638 5.06e-281 yqxK - - L - - - DNA helicase
CFDGDPAD_02639 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
CFDGDPAD_02640 2.65e-217 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
CFDGDPAD_02641 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
CFDGDPAD_02642 1.38e-223 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
CFDGDPAD_02643 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
CFDGDPAD_02644 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
CFDGDPAD_02645 3.23e-248 yqkA - - K - - - GrpB protein
CFDGDPAD_02646 2.25e-71 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
CFDGDPAD_02647 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
CFDGDPAD_02648 3.23e-66 yqiX - - S - - - YolD-like protein
CFDGDPAD_02649 4.9e-303 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFDGDPAD_02651 2.55e-288 yqjV - - G - - - Major Facilitator Superfamily
CFDGDPAD_02653 1.06e-92 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CFDGDPAD_02654 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
CFDGDPAD_02655 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
CFDGDPAD_02656 1.62e-183 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDGDPAD_02657 3.14e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
CFDGDPAD_02658 2.98e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CFDGDPAD_02659 0.0 rocB - - E - - - arginine degradation protein
CFDGDPAD_02660 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
CFDGDPAD_02661 3.86e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CFDGDPAD_02662 7.08e-26 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
CFDGDPAD_02663 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CFDGDPAD_02664 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CFDGDPAD_02665 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CFDGDPAD_02666 9.1e-300 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFDGDPAD_02667 1.77e-32 yqzJ - - - - - - -
CFDGDPAD_02668 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CFDGDPAD_02669 3.43e-181 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
CFDGDPAD_02670 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
CFDGDPAD_02671 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CFDGDPAD_02672 6.89e-97 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
CFDGDPAD_02674 2.82e-127 yqjB - - S - - - protein conserved in bacteria
CFDGDPAD_02675 4.95e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
CFDGDPAD_02676 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
CFDGDPAD_02677 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
CFDGDPAD_02678 5.83e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
CFDGDPAD_02679 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
CFDGDPAD_02680 1.72e-213 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CFDGDPAD_02681 6.23e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
CFDGDPAD_02682 3.69e-194 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
CFDGDPAD_02683 4.59e-289 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CFDGDPAD_02684 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CFDGDPAD_02685 2.24e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CFDGDPAD_02686 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CFDGDPAD_02687 3.39e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
CFDGDPAD_02688 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
CFDGDPAD_02689 1.74e-198 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
CFDGDPAD_02690 0.0 bkdR - - KT - - - Transcriptional regulator
CFDGDPAD_02691 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
CFDGDPAD_02692 7.23e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CFDGDPAD_02693 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
CFDGDPAD_02694 1.66e-267 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
CFDGDPAD_02695 5.16e-270 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
CFDGDPAD_02696 4.16e-200 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
CFDGDPAD_02697 5.7e-281 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
CFDGDPAD_02698 3.39e-168 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
CFDGDPAD_02699 1.63e-138 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
CFDGDPAD_02700 2.26e-37 - - - - - - - -
CFDGDPAD_02701 2.81e-273 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
CFDGDPAD_02703 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
CFDGDPAD_02704 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
CFDGDPAD_02705 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
CFDGDPAD_02706 1.53e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
CFDGDPAD_02707 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
CFDGDPAD_02708 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CFDGDPAD_02709 2.43e-208 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
CFDGDPAD_02710 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CFDGDPAD_02711 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CFDGDPAD_02712 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFDGDPAD_02713 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFDGDPAD_02714 1.65e-88 yqhY - - S - - - protein conserved in bacteria
CFDGDPAD_02715 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
CFDGDPAD_02716 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CFDGDPAD_02717 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
CFDGDPAD_02718 7.28e-147 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
CFDGDPAD_02719 5.2e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
CFDGDPAD_02720 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
CFDGDPAD_02721 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
CFDGDPAD_02722 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
CFDGDPAD_02723 8.09e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
CFDGDPAD_02724 3.35e-216 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
CFDGDPAD_02725 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
CFDGDPAD_02726 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFDGDPAD_02727 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
CFDGDPAD_02728 9.59e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
CFDGDPAD_02729 1.14e-120 yqhR - - S - - - Conserved membrane protein YqhR
CFDGDPAD_02730 1.48e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
CFDGDPAD_02731 5.18e-81 yqhP - - - - - - -
CFDGDPAD_02732 5.75e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
CFDGDPAD_02733 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
CFDGDPAD_02734 9.17e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
CFDGDPAD_02735 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
CFDGDPAD_02736 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFDGDPAD_02737 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CFDGDPAD_02738 5.26e-259 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
CFDGDPAD_02739 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
CFDGDPAD_02740 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
CFDGDPAD_02741 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
CFDGDPAD_02742 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
CFDGDPAD_02743 9e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
CFDGDPAD_02744 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
CFDGDPAD_02745 1.76e-159 yqxM - - - ko:K19433 - ko00000 -
CFDGDPAD_02746 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
CFDGDPAD_02747 4.9e-37 yqzE - - S - - - YqzE-like protein
CFDGDPAD_02748 1.88e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
CFDGDPAD_02749 2.9e-46 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
CFDGDPAD_02750 4.35e-79 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
CFDGDPAD_02751 9.7e-94 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
CFDGDPAD_02752 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
CFDGDPAD_02753 1.51e-219 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
CFDGDPAD_02754 7.43e-256 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CFDGDPAD_02756 7.17e-232 yqxL - - P - - - Mg2 transporter protein
CFDGDPAD_02757 5.77e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
CFDGDPAD_02758 2.49e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CFDGDPAD_02760 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
CFDGDPAD_02761 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
CFDGDPAD_02762 1.07e-155 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
CFDGDPAD_02763 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
CFDGDPAD_02764 8.58e-65 yqgV - - S - - - Thiamine-binding protein
CFDGDPAD_02765 3.27e-257 yqgU - - - - - - -
CFDGDPAD_02766 5.04e-282 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
CFDGDPAD_02767 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
CFDGDPAD_02768 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
CFDGDPAD_02769 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
CFDGDPAD_02770 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
CFDGDPAD_02771 3.38e-14 yqgO - - - - - - -
CFDGDPAD_02772 7.98e-137 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CFDGDPAD_02773 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
CFDGDPAD_02774 4.1e-250 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
CFDGDPAD_02776 2.81e-67 yqzD - - - - - - -
CFDGDPAD_02777 6.33e-93 yqzC - - S - - - YceG-like family
CFDGDPAD_02778 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CFDGDPAD_02779 9.78e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CFDGDPAD_02780 8.71e-201 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
CFDGDPAD_02781 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
CFDGDPAD_02782 4.51e-206 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
CFDGDPAD_02783 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
CFDGDPAD_02784 2.29e-292 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
CFDGDPAD_02785 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
CFDGDPAD_02786 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
CFDGDPAD_02787 2.74e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
CFDGDPAD_02788 2.84e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
CFDGDPAD_02789 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CFDGDPAD_02790 2.04e-81 yqfX - - S - - - membrane
CFDGDPAD_02791 6.79e-141 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
CFDGDPAD_02792 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
CFDGDPAD_02793 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
CFDGDPAD_02794 6.07e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
CFDGDPAD_02795 8.54e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CFDGDPAD_02796 5.42e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CFDGDPAD_02797 4.89e-58 yqfQ - - S - - - YqfQ-like protein
CFDGDPAD_02798 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CFDGDPAD_02799 3.77e-269 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CFDGDPAD_02800 1.98e-149 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
CFDGDPAD_02801 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
CFDGDPAD_02802 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CFDGDPAD_02803 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CFDGDPAD_02804 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
CFDGDPAD_02805 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CFDGDPAD_02806 3.29e-144 ccpN - - K - - - CBS domain
CFDGDPAD_02807 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
CFDGDPAD_02808 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
CFDGDPAD_02809 7.48e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
CFDGDPAD_02810 5.29e-27 - - - S - - - YqzL-like protein
CFDGDPAD_02811 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFDGDPAD_02812 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CFDGDPAD_02813 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
CFDGDPAD_02814 1.68e-103 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFDGDPAD_02815 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
CFDGDPAD_02817 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
CFDGDPAD_02818 2.33e-239 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
CFDGDPAD_02819 2.07e-60 yqfC - - S - - - sporulation protein YqfC
CFDGDPAD_02820 1.37e-73 yqfB - - - - - - -
CFDGDPAD_02821 2.06e-190 yqfA - - S - - - UPF0365 protein
CFDGDPAD_02822 7.62e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
CFDGDPAD_02823 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
CFDGDPAD_02824 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
CFDGDPAD_02825 4.02e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
CFDGDPAD_02826 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
CFDGDPAD_02827 1.38e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CFDGDPAD_02828 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
CFDGDPAD_02829 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CFDGDPAD_02830 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
CFDGDPAD_02831 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFDGDPAD_02832 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CFDGDPAD_02833 1.68e-275 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
CFDGDPAD_02834 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CFDGDPAD_02835 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
CFDGDPAD_02836 1.3e-281 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
CFDGDPAD_02837 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CFDGDPAD_02838 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
CFDGDPAD_02839 1.16e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
CFDGDPAD_02840 2.36e-22 - - - S - - - YqzM-like protein
CFDGDPAD_02841 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
CFDGDPAD_02842 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
CFDGDPAD_02843 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
CFDGDPAD_02844 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CFDGDPAD_02845 5.67e-178 yqeM - - Q - - - Methyltransferase
CFDGDPAD_02846 6.61e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CFDGDPAD_02847 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
CFDGDPAD_02848 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CFDGDPAD_02849 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
CFDGDPAD_02850 2.42e-200 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFDGDPAD_02851 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
CFDGDPAD_02852 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
CFDGDPAD_02854 2.61e-181 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
CFDGDPAD_02855 4.44e-172 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
CFDGDPAD_02856 2.3e-135 yqeD - - S - - - SNARE associated Golgi protein
CFDGDPAD_02857 4.88e-137 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
CFDGDPAD_02858 9.38e-65 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
CFDGDPAD_02859 9.38e-171 - - - - - - - -
CFDGDPAD_02860 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
CFDGDPAD_02861 2.91e-81 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
CFDGDPAD_02862 1.73e-282 yfjF - - EGP - - - Belongs to the major facilitator superfamily
CFDGDPAD_02863 0.0 - - - L ko:K06400 - ko00000 Recombinase
CFDGDPAD_02864 8.34e-134 ywqM - - K - - - Transcriptional regulator
CFDGDPAD_02865 1.45e-156 - - - E - - - amino acid
CFDGDPAD_02867 9.94e-169 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
CFDGDPAD_02870 2.72e-269 - - - M - - - nucleic acid phosphodiester bond hydrolysis
CFDGDPAD_02871 3.38e-38 - - - S - - - SMI1-KNR4 cell-wall
CFDGDPAD_02872 5.91e-41 - - - - - - - -
CFDGDPAD_02873 5.46e-32 - - - S - - - SMI1-KNR4 cell-wall
CFDGDPAD_02874 1.23e-19 - - - S - - - SMI1 / KNR4 family
CFDGDPAD_02875 1.83e-60 - - - - - - - -
CFDGDPAD_02879 5.3e-124 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
CFDGDPAD_02880 1.33e-40 - - - - - - - -
CFDGDPAD_02882 9.49e-10 xkdM - - S - - - Phage tail tube protein
CFDGDPAD_02883 5.07e-48 yqaS - - L - - - DNA packaging
CFDGDPAD_02884 0.000188 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
CFDGDPAD_02885 2.54e-36 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
CFDGDPAD_02886 3.63e-53 yqaQ - - L - - - Transposase
CFDGDPAD_02887 3.56e-08 - - - S - - - Bacillus cereus group antimicrobial protein
CFDGDPAD_02889 3.57e-49 yqaM - - L - - - IstB-like ATP binding protein
CFDGDPAD_02891 1.85e-204 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
CFDGDPAD_02892 1.31e-116 - - - K - - - Transcriptional regulator PadR-like family
CFDGDPAD_02893 1.5e-123 yqaC - - F - - - adenylate kinase activity
CFDGDPAD_02895 3.17e-59 xkdA - - E - - - IrrE N-terminal-like domain
CFDGDPAD_02896 1.81e-78 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFDGDPAD_02897 3.74e-143 tetR3 - - K ko:K18476 - ko00000,ko00002,ko03000 Transcriptional regulator
CFDGDPAD_02898 2.72e-275 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 Multidrug transporter MatE
CFDGDPAD_02899 1.26e-207 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
CFDGDPAD_02900 5.31e-155 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
CFDGDPAD_02901 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
CFDGDPAD_02902 4.88e-262 yrkH - - P - - - Rhodanese Homology Domain
CFDGDPAD_02903 4.61e-126 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
CFDGDPAD_02904 1.96e-108 yrkE - - O - - - DsrE/DsrF/DrsH-like family
CFDGDPAD_02905 4.38e-52 yrkD - - S - - - protein conserved in bacteria
CFDGDPAD_02906 2.21e-138 yrkC - - G - - - Cupin domain
CFDGDPAD_02907 5.9e-193 bltR - - K - - - helix_turn_helix, mercury resistance
CFDGDPAD_02908 1.31e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
CFDGDPAD_02909 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
CFDGDPAD_02910 1.25e-298 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
CFDGDPAD_02911 2.45e-23 - - - S - - - YrzO-like protein
CFDGDPAD_02912 1.53e-219 yrdR - - EG - - - EamA-like transporter family
CFDGDPAD_02913 3.3e-202 - - - K - - - Transcriptional regulator
CFDGDPAD_02914 1.01e-252 trkA - - P ko:K07222 - ko00000 Oxidoreductase
CFDGDPAD_02915 2.79e-202 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
CFDGDPAD_02916 1.75e-87 yodA - - S - - - tautomerase
CFDGDPAD_02917 4.34e-206 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
CFDGDPAD_02918 1.43e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
CFDGDPAD_02919 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
CFDGDPAD_02920 7.67e-175 azlC - - E - - - AzlC protein
CFDGDPAD_02921 4.13e-104 bkdR - - K - - - helix_turn_helix ASNC type
CFDGDPAD_02922 5.64e-45 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
CFDGDPAD_02923 5.86e-294 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
CFDGDPAD_02924 3.51e-129 yrdC - - Q - - - Isochorismatase family
CFDGDPAD_02925 6.04e-71 - - - S - - - Protein of unknown function (DUF2568)
CFDGDPAD_02926 3.9e-116 yrdA - - S - - - DinB family
CFDGDPAD_02927 8.39e-195 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
CFDGDPAD_02928 0.00014 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
CFDGDPAD_02929 4.23e-246 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
CFDGDPAD_02930 3.41e-188 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
CFDGDPAD_02931 5.63e-161 yrpD - - S - - - Domain of unknown function, YrpD
CFDGDPAD_02933 2.55e-167 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
CFDGDPAD_02934 1.24e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CFDGDPAD_02935 4.9e-239 yrpG - - C - - - Aldo/keto reductase family
CFDGDPAD_02936 2.93e-283 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
CFDGDPAD_02937 7e-209 yraN - - K - - - Transcriptional regulator
CFDGDPAD_02938 3.44e-262 yraM - - S - - - PrpF protein
CFDGDPAD_02939 5.73e-202 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
CFDGDPAD_02940 5.07e-56 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFDGDPAD_02941 8.04e-190 - - - S - - - Alpha beta hydrolase
CFDGDPAD_02942 1.33e-79 - - - T - - - sh3 domain protein
CFDGDPAD_02943 2.92e-81 - - - T - - - sh3 domain protein
CFDGDPAD_02944 6.62e-87 - - - E - - - Glyoxalase-like domain
CFDGDPAD_02945 4.19e-50 yraG - - - ko:K06440 - ko00000 -
CFDGDPAD_02946 9.61e-84 yraF - - M - - - Spore coat protein
CFDGDPAD_02947 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CFDGDPAD_02948 6.11e-36 yraE - - - ko:K06440 - ko00000 -
CFDGDPAD_02949 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
CFDGDPAD_02950 2.13e-66 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
CFDGDPAD_02951 1.02e-38 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
CFDGDPAD_02952 3.95e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
CFDGDPAD_02953 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
CFDGDPAD_02954 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
CFDGDPAD_02955 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
CFDGDPAD_02956 2.79e-166 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
CFDGDPAD_02957 8.91e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
CFDGDPAD_02958 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
CFDGDPAD_02959 0.0 levR - - K - - - PTS system fructose IIA component
CFDGDPAD_02960 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
CFDGDPAD_02961 1.14e-136 yrhP - - E - - - LysE type translocator
CFDGDPAD_02962 6.61e-191 yrhO - - K - - - Archaeal transcriptional regulator TrmB
CFDGDPAD_02963 9.97e-114 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CFDGDPAD_02964 1.43e-190 rsiV - - S - - - Protein of unknown function (DUF3298)
CFDGDPAD_02965 0.0 oatA - - I - - - Acyltransferase family
CFDGDPAD_02966 2.67e-62 yrhK - - S - - - YrhK-like protein
CFDGDPAD_02967 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
CFDGDPAD_02968 1.12e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
CFDGDPAD_02969 1.1e-126 yrhH - - Q - - - methyltransferase
CFDGDPAD_02970 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
CFDGDPAD_02972 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
CFDGDPAD_02973 1.08e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
CFDGDPAD_02974 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
CFDGDPAD_02975 4.26e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
CFDGDPAD_02976 6.93e-49 yrhC - - S - - - YrhC-like protein
CFDGDPAD_02977 8.19e-267 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
CFDGDPAD_02978 1.66e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
CFDGDPAD_02979 8.02e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFDGDPAD_02980 2.42e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
CFDGDPAD_02981 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
CFDGDPAD_02982 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
CFDGDPAD_02983 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
CFDGDPAD_02984 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CFDGDPAD_02985 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
CFDGDPAD_02986 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
CFDGDPAD_02987 1.27e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
CFDGDPAD_02988 1.7e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
CFDGDPAD_02989 4.34e-241 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFDGDPAD_02990 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
CFDGDPAD_02991 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFDGDPAD_02992 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
CFDGDPAD_02993 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFDGDPAD_02994 3.07e-242 yrrI - - S - - - AI-2E family transporter
CFDGDPAD_02995 1.89e-169 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
CFDGDPAD_02996 5.2e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
CFDGDPAD_02997 2.28e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CFDGDPAD_02998 7.61e-139 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CFDGDPAD_02999 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
CFDGDPAD_03000 8.4e-42 yrzR - - - - - - -
CFDGDPAD_03001 3.54e-108 yrrD - - S - - - protein conserved in bacteria
CFDGDPAD_03002 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CFDGDPAD_03003 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
CFDGDPAD_03004 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CFDGDPAD_03005 2.56e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
CFDGDPAD_03006 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_03007 8.5e-304 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
CFDGDPAD_03008 3.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
CFDGDPAD_03009 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CFDGDPAD_03010 3.5e-309 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
CFDGDPAD_03012 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
CFDGDPAD_03013 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CFDGDPAD_03014 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFDGDPAD_03015 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFDGDPAD_03016 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
CFDGDPAD_03017 4.35e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
CFDGDPAD_03018 2.09e-110 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
CFDGDPAD_03019 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CFDGDPAD_03020 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
CFDGDPAD_03021 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CFDGDPAD_03022 5.83e-143 yrbG - - S - - - membrane
CFDGDPAD_03023 1.46e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
CFDGDPAD_03024 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
CFDGDPAD_03025 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CFDGDPAD_03026 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFDGDPAD_03027 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
CFDGDPAD_03028 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CFDGDPAD_03029 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CFDGDPAD_03030 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
CFDGDPAD_03031 0.0 csbX - - EGP - - - the major facilitator superfamily
CFDGDPAD_03032 7.93e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
CFDGDPAD_03033 2.6e-149 yrzF - - T - - - serine threonine protein kinase
CFDGDPAD_03035 7.31e-67 - - - S - - - Family of unknown function (DUF5412)
CFDGDPAD_03036 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
CFDGDPAD_03037 4.1e-163 yebC - - K - - - transcriptional regulatory protein
CFDGDPAD_03038 1.47e-69 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CFDGDPAD_03039 4.02e-216 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
CFDGDPAD_03040 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CFDGDPAD_03041 3.42e-200 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
CFDGDPAD_03042 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
CFDGDPAD_03043 8.59e-293 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
CFDGDPAD_03044 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
CFDGDPAD_03045 1.43e-208 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
CFDGDPAD_03046 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
CFDGDPAD_03047 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFDGDPAD_03048 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
CFDGDPAD_03049 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
CFDGDPAD_03050 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
CFDGDPAD_03051 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
CFDGDPAD_03052 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
CFDGDPAD_03053 1.83e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
CFDGDPAD_03054 6.84e-185 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
CFDGDPAD_03055 2.05e-156 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
CFDGDPAD_03056 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
CFDGDPAD_03057 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
CFDGDPAD_03058 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
CFDGDPAD_03059 8.35e-163 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
CFDGDPAD_03060 1e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
CFDGDPAD_03061 3.51e-210 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
CFDGDPAD_03062 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
CFDGDPAD_03063 1.55e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
CFDGDPAD_03064 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CFDGDPAD_03065 1.53e-35 - - - - - - - -
CFDGDPAD_03066 2.29e-250 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CFDGDPAD_03067 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
CFDGDPAD_03068 8.3e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
CFDGDPAD_03069 3.7e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
CFDGDPAD_03070 8.33e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
CFDGDPAD_03071 8.91e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
CFDGDPAD_03072 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
CFDGDPAD_03073 7.77e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CFDGDPAD_03074 8.23e-117 ysxD - - - - - - -
CFDGDPAD_03075 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
CFDGDPAD_03076 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CFDGDPAD_03077 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
CFDGDPAD_03078 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFDGDPAD_03079 8.87e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CFDGDPAD_03080 1.11e-239 ysoA - - H - - - Tetratricopeptide repeat
CFDGDPAD_03081 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFDGDPAD_03082 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFDGDPAD_03083 1.06e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CFDGDPAD_03084 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFDGDPAD_03085 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CFDGDPAD_03086 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
CFDGDPAD_03087 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
CFDGDPAD_03089 3.32e-107 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
CFDGDPAD_03090 3.92e-180 ysnF - - S - - - protein conserved in bacteria
CFDGDPAD_03092 1.65e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
CFDGDPAD_03093 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFDGDPAD_03094 2.04e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CFDGDPAD_03095 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
CFDGDPAD_03096 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
CFDGDPAD_03097 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
CFDGDPAD_03098 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_03099 2.65e-102 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
CFDGDPAD_03100 2.33e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
CFDGDPAD_03101 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
CFDGDPAD_03102 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
CFDGDPAD_03103 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
CFDGDPAD_03104 3.96e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
CFDGDPAD_03105 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CFDGDPAD_03106 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
CFDGDPAD_03107 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
CFDGDPAD_03109 1.23e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
CFDGDPAD_03110 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
CFDGDPAD_03111 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
CFDGDPAD_03112 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_03113 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CFDGDPAD_03114 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
CFDGDPAD_03115 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CFDGDPAD_03116 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
CFDGDPAD_03117 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
CFDGDPAD_03118 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CFDGDPAD_03119 2.76e-218 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFDGDPAD_03120 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CFDGDPAD_03121 7.36e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFDGDPAD_03122 2.57e-170 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFDGDPAD_03123 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
CFDGDPAD_03124 6.71e-265 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
CFDGDPAD_03125 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
CFDGDPAD_03126 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
CFDGDPAD_03127 3.09e-70 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
CFDGDPAD_03129 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
CFDGDPAD_03130 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
CFDGDPAD_03131 1.05e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
CFDGDPAD_03132 5.56e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
CFDGDPAD_03133 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
CFDGDPAD_03134 9.53e-285 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
CFDGDPAD_03135 2.03e-185 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
CFDGDPAD_03136 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
CFDGDPAD_03137 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
CFDGDPAD_03138 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
CFDGDPAD_03139 4.21e-243 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
CFDGDPAD_03140 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
CFDGDPAD_03141 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
CFDGDPAD_03142 1.27e-59 ysdA - - S - - - Membrane
CFDGDPAD_03143 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFDGDPAD_03144 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
CFDGDPAD_03145 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFDGDPAD_03147 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CFDGDPAD_03148 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CFDGDPAD_03149 5.62e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
CFDGDPAD_03150 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFDGDPAD_03151 1.2e-190 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
CFDGDPAD_03152 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFDGDPAD_03154 5.98e-206 ytxC - - S - - - YtxC-like family
CFDGDPAD_03155 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
CFDGDPAD_03156 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
CFDGDPAD_03157 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
CFDGDPAD_03158 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CFDGDPAD_03159 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CFDGDPAD_03160 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CFDGDPAD_03161 9.85e-88 ytcD - - K - - - Transcriptional regulator
CFDGDPAD_03162 9.22e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
CFDGDPAD_03163 4.54e-205 ytbE - - S - - - reductase
CFDGDPAD_03164 3.29e-125 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CFDGDPAD_03165 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
CFDGDPAD_03166 1.92e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CFDGDPAD_03167 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFDGDPAD_03168 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
CFDGDPAD_03169 3.27e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDGDPAD_03170 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
CFDGDPAD_03171 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
CFDGDPAD_03172 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
CFDGDPAD_03173 1.56e-93 ytwI - - S - - - membrane
CFDGDPAD_03174 2.24e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
CFDGDPAD_03175 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
CFDGDPAD_03176 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
CFDGDPAD_03177 1.62e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CFDGDPAD_03178 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
CFDGDPAD_03179 1.03e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CFDGDPAD_03180 6.01e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
CFDGDPAD_03181 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
CFDGDPAD_03182 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
CFDGDPAD_03183 5.12e-112 ytrI - - - - - - -
CFDGDPAD_03184 1.15e-39 - - - - - - - -
CFDGDPAD_03185 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
CFDGDPAD_03186 2.15e-63 ytpI - - S - - - YtpI-like protein
CFDGDPAD_03187 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
CFDGDPAD_03188 2.24e-206 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
CFDGDPAD_03189 3.05e-299 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
CFDGDPAD_03190 5.44e-163 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
CFDGDPAD_03191 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFDGDPAD_03192 2.14e-62 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
CFDGDPAD_03193 2.51e-236 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFDGDPAD_03194 5.43e-182 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
CFDGDPAD_03195 1.86e-152 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CFDGDPAD_03196 4.36e-153 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CFDGDPAD_03197 2.19e-187 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
CFDGDPAD_03198 3.18e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
CFDGDPAD_03199 3.42e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
CFDGDPAD_03200 2.89e-222 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
CFDGDPAD_03201 7.78e-166 ytkL - - S - - - Belongs to the UPF0173 family
CFDGDPAD_03202 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDGDPAD_03204 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
CFDGDPAD_03205 8.67e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
CFDGDPAD_03206 8.14e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
CFDGDPAD_03207 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFDGDPAD_03208 1.79e-222 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
CFDGDPAD_03209 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CFDGDPAD_03210 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
CFDGDPAD_03211 5.63e-147 ytfI - - S - - - Protein of unknown function (DUF2953)
CFDGDPAD_03212 2.36e-111 yteJ - - S - - - RDD family
CFDGDPAD_03213 1.13e-228 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
CFDGDPAD_03214 2.92e-190 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFDGDPAD_03215 0.0 ytcJ - - S - - - amidohydrolase
CFDGDPAD_03216 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CFDGDPAD_03217 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
CFDGDPAD_03218 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFDGDPAD_03219 4.75e-267 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
CFDGDPAD_03220 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
CFDGDPAD_03221 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CFDGDPAD_03222 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
CFDGDPAD_03223 1.2e-141 yttP - - K - - - Transcriptional regulator
CFDGDPAD_03224 5.59e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
CFDGDPAD_03225 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
CFDGDPAD_03226 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFDGDPAD_03228 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFDGDPAD_03229 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CFDGDPAD_03230 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
CFDGDPAD_03231 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
CFDGDPAD_03232 3.82e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
CFDGDPAD_03233 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
CFDGDPAD_03234 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
CFDGDPAD_03235 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
CFDGDPAD_03236 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
CFDGDPAD_03237 1.57e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
CFDGDPAD_03238 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
CFDGDPAD_03239 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CFDGDPAD_03240 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
CFDGDPAD_03241 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
CFDGDPAD_03242 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CFDGDPAD_03243 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
CFDGDPAD_03244 3.17e-75 ytpP - - CO - - - Thioredoxin
CFDGDPAD_03245 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
CFDGDPAD_03246 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
CFDGDPAD_03247 6.75e-67 ytzB - - S - - - small secreted protein
CFDGDPAD_03248 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
CFDGDPAD_03249 7.23e-192 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
CFDGDPAD_03250 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CFDGDPAD_03251 9.51e-61 ytzH - - S - - - YtzH-like protein
CFDGDPAD_03252 3.02e-192 ytmP - - M - - - Phosphotransferase
CFDGDPAD_03253 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
CFDGDPAD_03254 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
CFDGDPAD_03255 2e-211 ytlQ - - - - - - -
CFDGDPAD_03256 4.29e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CFDGDPAD_03257 6.05e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
CFDGDPAD_03258 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
CFDGDPAD_03259 1.65e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
CFDGDPAD_03260 1.17e-253 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
CFDGDPAD_03261 8.04e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
CFDGDPAD_03262 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
CFDGDPAD_03263 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
CFDGDPAD_03264 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CFDGDPAD_03265 1.41e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
CFDGDPAD_03266 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
CFDGDPAD_03267 2.14e-36 yteV - - S - - - Sporulation protein Cse60
CFDGDPAD_03268 1.05e-147 yteU - - S - - - Integral membrane protein
CFDGDPAD_03269 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
CFDGDPAD_03270 3.36e-94 yteS - - G - - - transport
CFDGDPAD_03271 1.88e-275 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
CFDGDPAD_03272 1.87e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
CFDGDPAD_03273 0.0 ytdP - - K - - - Transcriptional regulator
CFDGDPAD_03274 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
CFDGDPAD_03275 2.52e-192 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
CFDGDPAD_03276 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
CFDGDPAD_03277 3.75e-287 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
CFDGDPAD_03278 2.64e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CFDGDPAD_03279 9.36e-160 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CFDGDPAD_03280 3.01e-274 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CFDGDPAD_03281 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
CFDGDPAD_03282 1.58e-179 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
CFDGDPAD_03283 7.95e-220 - - - S - - - Acetyl xylan esterase (AXE1)
CFDGDPAD_03284 2.64e-243 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_03285 7.71e-314 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
CFDGDPAD_03286 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
CFDGDPAD_03287 8.93e-185 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
CFDGDPAD_03288 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
CFDGDPAD_03289 1.22e-68 ytwF - - P - - - Sulfurtransferase
CFDGDPAD_03290 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
CFDGDPAD_03291 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
CFDGDPAD_03292 5.43e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
CFDGDPAD_03293 6.01e-269 yttB - - EGP - - - Major facilitator superfamily
CFDGDPAD_03294 3.78e-76 yttA - - S - - - Pfam Transposase IS66
CFDGDPAD_03295 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
CFDGDPAD_03296 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_03297 4.53e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
CFDGDPAD_03298 1.29e-166 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDGDPAD_03299 9.81e-297 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
CFDGDPAD_03300 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_03301 6.47e-191 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
CFDGDPAD_03302 4.87e-215 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
CFDGDPAD_03303 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_03304 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
CFDGDPAD_03306 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
CFDGDPAD_03307 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
CFDGDPAD_03308 2.75e-136 ytqB - - J - - - Putative rRNA methylase
CFDGDPAD_03309 1.54e-272 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
CFDGDPAD_03310 4.7e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
CFDGDPAD_03311 5.88e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CFDGDPAD_03312 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
CFDGDPAD_03313 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
CFDGDPAD_03314 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFDGDPAD_03315 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CFDGDPAD_03316 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
CFDGDPAD_03317 3.86e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
CFDGDPAD_03318 1.87e-240 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
CFDGDPAD_03319 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
CFDGDPAD_03320 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
CFDGDPAD_03321 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
CFDGDPAD_03322 5.32e-80 ytkC - - S - - - Bacteriophage holin family
CFDGDPAD_03323 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
CFDGDPAD_03325 4.78e-95 ytkA - - S - - - YtkA-like
CFDGDPAD_03326 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CFDGDPAD_03327 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
CFDGDPAD_03328 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
CFDGDPAD_03329 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
CFDGDPAD_03330 2.96e-241 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
CFDGDPAD_03331 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
CFDGDPAD_03332 5.58e-193 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
CFDGDPAD_03333 3.17e-297 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
CFDGDPAD_03334 1.5e-179 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
CFDGDPAD_03335 9.26e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
CFDGDPAD_03336 4.09e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
CFDGDPAD_03337 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CFDGDPAD_03338 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CFDGDPAD_03339 9.85e-197 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
CFDGDPAD_03340 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CFDGDPAD_03341 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
CFDGDPAD_03342 1.75e-168 yteA - - T - - - COG1734 DnaK suppressor protein
CFDGDPAD_03343 1.7e-196 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
CFDGDPAD_03344 4.79e-309 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CFDGDPAD_03345 5.23e-229 ytcB - - M - - - NAD-dependent epimerase dehydratase
CFDGDPAD_03346 1.24e-298 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
CFDGDPAD_03348 4.88e-263 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
CFDGDPAD_03349 1.75e-276 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
CFDGDPAD_03350 3.16e-261 cotI - - S ko:K06331 - ko00000 Spore coat protein
CFDGDPAD_03351 1.14e-100 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
CFDGDPAD_03352 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CFDGDPAD_03353 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
CFDGDPAD_03354 2.15e-237 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
CFDGDPAD_03355 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CFDGDPAD_03356 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CFDGDPAD_03378 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
CFDGDPAD_03379 5.46e-74 ygzB - - S - - - UPF0295 protein
CFDGDPAD_03380 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
CFDGDPAD_03381 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
CFDGDPAD_03382 1.19e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
CFDGDPAD_03383 1.87e-238 ygaE - - S - - - Membrane
CFDGDPAD_03384 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
CFDGDPAD_03385 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
CFDGDPAD_03386 2.01e-49 ygaB - - S - - - YgaB-like protein
CFDGDPAD_03387 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
CFDGDPAD_03388 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDGDPAD_03389 1.73e-48 yfhS - - - - - - -
CFDGDPAD_03390 1.31e-265 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
CFDGDPAD_03391 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
CFDGDPAD_03392 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
CFDGDPAD_03393 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
CFDGDPAD_03394 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
CFDGDPAD_03395 1.81e-65 yfhL - - S - - - SdpI/YhfL protein family
CFDGDPAD_03396 3.58e-119 yfhK - - T - - - Bacterial SH3 domain homologues
CFDGDPAD_03397 8.95e-60 yfhJ - - S - - - WVELL protein
CFDGDPAD_03398 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
CFDGDPAD_03399 3.47e-268 yfhI - - EGP - - - -transporter
CFDGDPAD_03401 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
CFDGDPAD_03402 3.25e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
CFDGDPAD_03403 9.3e-221 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
CFDGDPAD_03405 8.86e-35 yfhD - - S - - - YfhD-like protein
CFDGDPAD_03406 2.87e-138 yfhC - - C - - - nitroreductase
CFDGDPAD_03407 1.26e-213 yfhB - - S - - - PhzF family
CFDGDPAD_03408 4.25e-228 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDGDPAD_03409 1.54e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDGDPAD_03410 2.81e-233 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
CFDGDPAD_03411 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CFDGDPAD_03412 1.27e-104 yfiV - - K - - - transcriptional
CFDGDPAD_03413 0.0 yfiU - - EGP - - - the major facilitator superfamily
CFDGDPAD_03414 6.37e-125 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
CFDGDPAD_03415 2.99e-249 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CFDGDPAD_03416 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
CFDGDPAD_03417 1.89e-128 padR - - K - - - transcriptional
CFDGDPAD_03418 3.84e-259 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
CFDGDPAD_03419 2.53e-265 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
CFDGDPAD_03420 5.33e-215 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_03421 1.01e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
CFDGDPAD_03422 1.15e-270 baeS - - T - - - Histidine kinase
CFDGDPAD_03424 1.47e-208 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
CFDGDPAD_03425 2.01e-84 yfiD3 - - S - - - DoxX
CFDGDPAD_03426 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
CFDGDPAD_03427 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
CFDGDPAD_03428 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
CFDGDPAD_03429 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CFDGDPAD_03430 2.13e-181 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
CFDGDPAD_03431 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CFDGDPAD_03432 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
CFDGDPAD_03433 5.56e-270 yfjB - - - - - - -
CFDGDPAD_03434 2.5e-185 yfjC - - - - - - -
CFDGDPAD_03435 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
CFDGDPAD_03436 1.59e-102 - - - S - - - Family of unknown function (DUF5381)
CFDGDPAD_03437 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
CFDGDPAD_03438 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
CFDGDPAD_03439 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
CFDGDPAD_03440 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CFDGDPAD_03441 4.19e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CFDGDPAD_03442 3.59e-240 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CFDGDPAD_03443 2.75e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CFDGDPAD_03445 2.96e-105 yfjM - - S - - - Psort location Cytoplasmic, score
CFDGDPAD_03446 1.92e-240 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFDGDPAD_03447 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFDGDPAD_03448 5.74e-207 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CFDGDPAD_03449 3.05e-234 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
CFDGDPAD_03450 1.8e-189 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
CFDGDPAD_03451 7.24e-198 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
CFDGDPAD_03452 3.26e-36 yfjT - - - - - - -
CFDGDPAD_03453 1.76e-283 yfkA - - S - - - YfkB-like domain
CFDGDPAD_03454 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
CFDGDPAD_03455 3.69e-189 yfkD - - S - - - YfkD-like protein
CFDGDPAD_03456 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
CFDGDPAD_03457 1.1e-277 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
CFDGDPAD_03458 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
CFDGDPAD_03459 1.03e-66 yfkI - - S - - - gas vesicle protein
CFDGDPAD_03460 3.99e-106 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFDGDPAD_03461 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
CFDGDPAD_03462 1.7e-263 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
CFDGDPAD_03463 7.78e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
CFDGDPAD_03464 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
CFDGDPAD_03465 6.16e-160 frp - - C - - - nitroreductase
CFDGDPAD_03466 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
CFDGDPAD_03467 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
CFDGDPAD_03468 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CFDGDPAD_03469 2.74e-17 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
CFDGDPAD_03470 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
CFDGDPAD_03471 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
CFDGDPAD_03472 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
CFDGDPAD_03473 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
CFDGDPAD_03474 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
CFDGDPAD_03475 1.48e-65 yflH - - S - - - Protein of unknown function (DUF3243)
CFDGDPAD_03476 9.81e-27 yflI - - - - - - -
CFDGDPAD_03477 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
CFDGDPAD_03478 1.15e-155 yflK - - S - - - protein conserved in bacteria
CFDGDPAD_03479 2.09e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
CFDGDPAD_03480 1.13e-274 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CFDGDPAD_03481 5.93e-193 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
CFDGDPAD_03482 2.18e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
CFDGDPAD_03483 2.4e-231 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
CFDGDPAD_03484 1.88e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
CFDGDPAD_03485 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
CFDGDPAD_03486 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
CFDGDPAD_03487 2.45e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
CFDGDPAD_03488 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
CFDGDPAD_03489 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
CFDGDPAD_03490 5.57e-219 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
CFDGDPAD_03491 4.72e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDGDPAD_03492 5.76e-221 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDGDPAD_03493 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
CFDGDPAD_03494 1.41e-240 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
CFDGDPAD_03495 2.55e-105 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
CFDGDPAD_03496 2.42e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
CFDGDPAD_03497 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CFDGDPAD_03498 1.69e-24 - - - - - - - -
CFDGDPAD_03499 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
CFDGDPAD_03500 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
CFDGDPAD_03501 1.08e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
CFDGDPAD_03502 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CFDGDPAD_03503 1.47e-160 yfmS - - NT - - - chemotaxis protein
CFDGDPAD_03504 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CFDGDPAD_03505 3.41e-312 yfnA - - E ko:K03294 - ko00000 amino acid
CFDGDPAD_03506 7.44e-168 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
CFDGDPAD_03507 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CFDGDPAD_03508 3.88e-242 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
CFDGDPAD_03509 3.32e-284 yfnE - - S - - - Glycosyltransferase like family 2
CFDGDPAD_03510 3.99e-231 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
CFDGDPAD_03511 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
CFDGDPAD_03512 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
CFDGDPAD_03513 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
CFDGDPAD_03514 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
CFDGDPAD_03515 6.1e-255 yetN - - S - - - Protein of unknown function (DUF3900)
CFDGDPAD_03516 1.94e-269 yetM - - CH - - - FAD binding domain
CFDGDPAD_03517 3.08e-113 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
CFDGDPAD_03518 4.95e-201 - - - EG - - - EamA-like transporter family
CFDGDPAD_03519 2.55e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
CFDGDPAD_03520 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
CFDGDPAD_03521 3.59e-184 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CFDGDPAD_03522 9.79e-45 - - - - - - - -
CFDGDPAD_03523 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CFDGDPAD_03524 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
CFDGDPAD_03525 1.49e-156 yetF - - S - - - membrane
CFDGDPAD_03526 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
CFDGDPAD_03527 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CFDGDPAD_03528 1.01e-227 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
CFDGDPAD_03529 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
CFDGDPAD_03530 0.0 yetA - - - - - - -
CFDGDPAD_03531 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
CFDGDPAD_03532 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
CFDGDPAD_03533 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
CFDGDPAD_03534 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
CFDGDPAD_03535 9.47e-144 - - - S - - - Protein of unknown function, DUF624
CFDGDPAD_03536 4.35e-164 yesU - - S - - - Domain of unknown function (DUF1961)
CFDGDPAD_03537 5.22e-164 - - - E - - - GDSL-like Lipase/Acylhydrolase
CFDGDPAD_03538 0.0 yesS - - K - - - Transcriptional regulator
CFDGDPAD_03539 8e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
CFDGDPAD_03540 1.26e-210 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CFDGDPAD_03541 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
CFDGDPAD_03542 1.44e-314 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
CFDGDPAD_03543 1.05e-252 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
CFDGDPAD_03544 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFDGDPAD_03545 2.56e-132 yesL - - S - - - Protein of unknown function, DUF624
CFDGDPAD_03547 5.66e-129 yesJ - - K - - - Acetyltransferase (GNAT) family
CFDGDPAD_03548 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
CFDGDPAD_03549 1.34e-60 cotJB - - S ko:K06333 - ko00000 CotJB protein
CFDGDPAD_03550 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
CFDGDPAD_03551 2.37e-193 yesF - - GM - - - NAD(P)H-binding
CFDGDPAD_03552 4.76e-105 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
CFDGDPAD_03553 2.17e-133 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
CFDGDPAD_03555 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
CFDGDPAD_03557 2.87e-270 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
CFDGDPAD_03559 1.36e-177 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
CFDGDPAD_03560 1.14e-125 - - - L - - - endonuclease activity
CFDGDPAD_03562 2.05e-228 - - - S - - - Bacterial EndoU nuclease
CFDGDPAD_03563 2.42e-54 - - - S - - - Immunity protein 22
CFDGDPAD_03565 3.2e-124 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
CFDGDPAD_03567 6.61e-167 - - - K - - - Pfam:DUF955
CFDGDPAD_03568 1.05e-47 - - - S - - - Plasmid maintenance system killer
CFDGDPAD_03569 7.55e-148 cll - - - - - - -
CFDGDPAD_03570 7.52e-163 - - - - - - - -
CFDGDPAD_03571 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFDGDPAD_03572 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CFDGDPAD_03573 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CFDGDPAD_03574 4.21e-190 yerO - - K - - - Transcriptional regulator
CFDGDPAD_03575 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFDGDPAD_03576 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CFDGDPAD_03577 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFDGDPAD_03578 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFDGDPAD_03579 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
CFDGDPAD_03580 2.45e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
CFDGDPAD_03581 2.41e-279 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
CFDGDPAD_03582 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFDGDPAD_03583 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
CFDGDPAD_03584 6.36e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CFDGDPAD_03585 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
CFDGDPAD_03586 7.62e-68 yerC - - S - - - protein conserved in bacteria
CFDGDPAD_03587 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
CFDGDPAD_03588 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
CFDGDPAD_03589 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
CFDGDPAD_03590 5.58e-271 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
CFDGDPAD_03591 1.06e-95 - - - K - - - helix_turn_helix ASNC type
CFDGDPAD_03592 1.63e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
CFDGDPAD_03593 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
CFDGDPAD_03594 8.88e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFDGDPAD_03595 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
CFDGDPAD_03596 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFDGDPAD_03597 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFDGDPAD_03598 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFDGDPAD_03599 2.2e-51 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFDGDPAD_03600 1.18e-167 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
CFDGDPAD_03601 5.65e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFDGDPAD_03602 7.71e-277 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFDGDPAD_03603 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFDGDPAD_03604 3.13e-38 yebG - - S - - - NETI protein
CFDGDPAD_03605 2.66e-120 yebE - - S - - - UPF0316 protein
CFDGDPAD_03607 5.85e-165 yebC - - M - - - Membrane
CFDGDPAD_03608 3.27e-281 pbuG - - S ko:K06901 - ko00000,ko02000 permease
CFDGDPAD_03609 2.21e-312 - - - S - - - Domain of unknown function (DUF4179)
CFDGDPAD_03610 1.33e-112 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CFDGDPAD_03611 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
CFDGDPAD_03612 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
CFDGDPAD_03613 8.42e-281 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
CFDGDPAD_03614 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
CFDGDPAD_03615 4.13e-197 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFDGDPAD_03616 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
CFDGDPAD_03617 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
CFDGDPAD_03618 7.65e-226 yeaA - - S - - - Protein of unknown function (DUF4003)
CFDGDPAD_03619 1.2e-200 - - - I - - - Alpha/beta hydrolase family
CFDGDPAD_03620 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
CFDGDPAD_03622 9.38e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
CFDGDPAD_03623 1.79e-84 ydjM - - M - - - Lytic transglycolase
CFDGDPAD_03624 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
CFDGDPAD_03625 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CFDGDPAD_03626 1.1e-142 - - - S - - - Ion transport 2 domain protein
CFDGDPAD_03627 1.48e-221 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
CFDGDPAD_03628 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
CFDGDPAD_03629 1.24e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
CFDGDPAD_03630 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
CFDGDPAD_03631 2.69e-193 ydjC - - S - - - Abhydrolase domain containing 18
CFDGDPAD_03634 1.64e-106 - - - - - - - -
CFDGDPAD_03635 1.36e-37 - - - K - - - Helix-turn-helix domain
CFDGDPAD_03637 4.72e-51 - - - S - - - protein domain associated with
CFDGDPAD_03638 2.05e-158 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
CFDGDPAD_03639 1.25e-38 xhlB - - S - - - SPP1 phage holin
CFDGDPAD_03640 7.72e-37 xhlA - - S - - - Haemolysin XhlA
CFDGDPAD_03641 4.24e-122 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
CFDGDPAD_03643 4.39e-12 - - - - - - - -
CFDGDPAD_03644 2.68e-22 - - - - - - - -
CFDGDPAD_03645 1.22e-78 - - - - - - - -
CFDGDPAD_03646 1.84e-130 - - - S - - - homolog of phage Mu protein gp47
CFDGDPAD_03647 6.43e-30 - - - S - - - Protein of unknown function (DUF2634)
CFDGDPAD_03649 3.69e-111 - - - - - - - -
CFDGDPAD_03650 1.13e-41 - - - - - - - -
CFDGDPAD_03651 6.22e-47 - - - M - - - LysM domain
CFDGDPAD_03652 2.41e-161 - - - N - - - phage tail tape measure protein
CFDGDPAD_03653 1.59e-10 - - - - - - - -
CFDGDPAD_03654 8.46e-46 - - - - - - - -
CFDGDPAD_03655 4.59e-128 - - - S - - - Protein of unknown function (DUF3383)
CFDGDPAD_03656 6.84e-40 - - - - - - - -
CFDGDPAD_03658 2.44e-61 - - - - - - - -
CFDGDPAD_03660 1.04e-39 - - - S - - - Phage Mu protein F like protein
CFDGDPAD_03662 8.27e-157 - - - S - - - Phage capsid family
CFDGDPAD_03663 4.59e-77 - - - S - - - Domain of unknown function (DUF4355)
CFDGDPAD_03665 1.61e-192 - - - S - - - Phage portal protein, SPP1 Gp6-like
CFDGDPAD_03666 5.15e-233 - - - S - - - Terminase-like family
CFDGDPAD_03667 7.14e-113 yqaS - - L - - - DNA packaging
CFDGDPAD_03670 8.99e-20 - - - K - - - Transcriptional regulator
CFDGDPAD_03672 4.33e-90 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
CFDGDPAD_03678 2.97e-26 yqaO - - S - - - Phage-like element PBSX protein XtrA
CFDGDPAD_03680 1.83e-70 - - - S - - - Protein of unknown function (DUF1064)
CFDGDPAD_03681 6.29e-13 - - - S - - - YopX protein
CFDGDPAD_03683 5.09e-164 yqaM - - L - - - IstB-like ATP binding protein
CFDGDPAD_03684 1.23e-43 yqaL - - L - - - DnaD domain protein
CFDGDPAD_03685 2.54e-171 recT - - L ko:K07455 - ko00000,ko03400 RecT family
CFDGDPAD_03686 1.33e-193 yqaJ - - L - - - YqaJ-like viral recombinase domain
CFDGDPAD_03691 4.65e-112 - - - - - - - -
CFDGDPAD_03692 5.93e-93 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
CFDGDPAD_03693 9.71e-48 - - - - - - - -
CFDGDPAD_03694 3e-05 - - - K - - - Helix-turn-helix domain
CFDGDPAD_03695 1.01e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
CFDGDPAD_03697 4.37e-84 - - - - - - - -
CFDGDPAD_03698 2.92e-43 - - - S - - - Protein of unknown function (DUF4064)
CFDGDPAD_03699 1.35e-61 xkdA - - E - - - IrrE N-terminal-like domain
CFDGDPAD_03700 1.56e-181 - - - L - - - Belongs to the 'phage' integrase family
CFDGDPAD_03701 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CFDGDPAD_03702 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFDGDPAD_03703 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
CFDGDPAD_03704 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
CFDGDPAD_03705 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFDGDPAD_03706 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CFDGDPAD_03707 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CFDGDPAD_03708 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
CFDGDPAD_03709 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
CFDGDPAD_03710 5.46e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFDGDPAD_03711 4.91e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CFDGDPAD_03712 2.8e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
CFDGDPAD_03713 3.68e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
CFDGDPAD_03714 9.03e-230 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CFDGDPAD_03717 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDGDPAD_03718 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
CFDGDPAD_03719 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
CFDGDPAD_03720 6.26e-288 - - - EGP - - - Major Facilitator Superfamily
CFDGDPAD_03721 6.03e-122 - - - S - - - YcxB-like protein
CFDGDPAD_03722 3.27e-205 ycxC - - EG - - - EamA-like transporter family
CFDGDPAD_03723 0.0 ycxD - - K - - - GntR family transcriptional regulator
CFDGDPAD_03724 1.94e-144 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
CFDGDPAD_03725 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
CFDGDPAD_03726 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
CFDGDPAD_03727 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
CFDGDPAD_03728 1.23e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
CFDGDPAD_03729 8.83e-208 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
CFDGDPAD_03730 1.35e-141 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
CFDGDPAD_03731 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
CFDGDPAD_03732 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
CFDGDPAD_03733 1.34e-103 yclD - - - - - - -
CFDGDPAD_03734 3.87e-202 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
CFDGDPAD_03735 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
CFDGDPAD_03736 0.0 yclG - - M - - - Pectate lyase superfamily protein
CFDGDPAD_03738 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
CFDGDPAD_03739 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
CFDGDPAD_03740 2.29e-254 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
CFDGDPAD_03741 5.87e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
CFDGDPAD_03742 6.2e-277 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
CFDGDPAD_03743 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDGDPAD_03744 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
CFDGDPAD_03745 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
CFDGDPAD_03747 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
CFDGDPAD_03748 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
CFDGDPAD_03749 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDGDPAD_03750 2.23e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDGDPAD_03751 5.63e-176 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_03752 1.94e-220 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
CFDGDPAD_03753 0.0 ycnB - - EGP - - - the major facilitator superfamily
CFDGDPAD_03754 6.85e-197 ycnC - - K - - - Transcriptional regulator
CFDGDPAD_03755 2.48e-173 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
CFDGDPAD_03756 1.68e-60 ycnE - - S - - - Monooxygenase
CFDGDPAD_03757 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
CFDGDPAD_03758 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CFDGDPAD_03759 8.96e-309 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CFDGDPAD_03760 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CFDGDPAD_03761 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
CFDGDPAD_03762 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDGDPAD_03763 6.62e-133 ycnI - - S - - - protein conserved in bacteria
CFDGDPAD_03764 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
CFDGDPAD_03765 8.26e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
CFDGDPAD_03766 9.44e-75 - - - - - - - -
CFDGDPAD_03767 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
CFDGDPAD_03768 2.38e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
CFDGDPAD_03769 2.97e-266 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
CFDGDPAD_03770 2.29e-253 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
CFDGDPAD_03772 6.21e-97 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
CFDGDPAD_03773 3.08e-146 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
CFDGDPAD_03774 9.34e-88 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
CFDGDPAD_03776 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
CFDGDPAD_03777 1.1e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
CFDGDPAD_03778 2.78e-273 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
CFDGDPAD_03779 2.01e-189 ycsI - - S - - - Belongs to the D-glutamate cyclase family
CFDGDPAD_03780 4.84e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
CFDGDPAD_03781 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
CFDGDPAD_03782 3.8e-171 kipR - - K - - - Transcriptional regulator
CFDGDPAD_03783 8.44e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
CFDGDPAD_03785 7.67e-66 yczJ - - S - - - biosynthesis
CFDGDPAD_03786 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
CFDGDPAD_03787 3e-220 ycsN - - S - - - Oxidoreductase
CFDGDPAD_03788 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
CFDGDPAD_03789 0.0 ydaB - - IQ - - - acyl-CoA ligase
CFDGDPAD_03790 1e-127 ydaC - - Q - - - Methyltransferase domain
CFDGDPAD_03791 1.25e-205 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CFDGDPAD_03792 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
CFDGDPAD_03793 1.33e-133 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CFDGDPAD_03794 5.24e-101 ydaG - - S - - - general stress protein
CFDGDPAD_03795 2.65e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
CFDGDPAD_03796 3.12e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
CFDGDPAD_03797 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
CFDGDPAD_03798 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFDGDPAD_03799 6.96e-264 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
CFDGDPAD_03800 1.33e-194 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
CFDGDPAD_03801 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
CFDGDPAD_03802 5.53e-304 ydaM - - M - - - Glycosyl transferase family group 2
CFDGDPAD_03803 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
CFDGDPAD_03804 0.0 ydaO - - E - - - amino acid
CFDGDPAD_03805 1.21e-99 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
CFDGDPAD_03806 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
CFDGDPAD_03808 2.5e-52 - - - - - - - -
CFDGDPAD_03809 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
CFDGDPAD_03810 1.67e-42 ydaS - - S - - - membrane
CFDGDPAD_03811 9.17e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
CFDGDPAD_03812 1.68e-187 ydbA - - P - - - EcsC protein family
CFDGDPAD_03813 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
CFDGDPAD_03814 7.58e-79 ydbB - - G - - - Cupin domain
CFDGDPAD_03815 4.45e-83 ydbC - - S - - - Domain of unknown function (DUF4937
CFDGDPAD_03816 7.49e-196 ydbD - - P ko:K07217 - ko00000 Catalase
CFDGDPAD_03817 1.23e-251 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
CFDGDPAD_03818 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
CFDGDPAD_03819 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
CFDGDPAD_03820 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CFDGDPAD_03821 1.32e-230 ydbI - - S - - - AI-2E family transporter
CFDGDPAD_03822 1.32e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_03823 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CFDGDPAD_03824 9.32e-70 ydbL - - - - - - -
CFDGDPAD_03825 1.5e-279 ydbM - - I - - - acyl-CoA dehydrogenase
CFDGDPAD_03826 1.49e-26 - - - S - - - Fur-regulated basic protein B
CFDGDPAD_03827 2.1e-11 - - - S - - - Fur-regulated basic protein A
CFDGDPAD_03828 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFDGDPAD_03829 4.19e-75 ydbP - - CO - - - Thioredoxin
CFDGDPAD_03830 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
CFDGDPAD_03831 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CFDGDPAD_03832 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CFDGDPAD_03833 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
CFDGDPAD_03834 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
CFDGDPAD_03835 2.96e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
CFDGDPAD_03836 1.6e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CFDGDPAD_03837 1.9e-233 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
CFDGDPAD_03838 1.77e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFDGDPAD_03839 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
CFDGDPAD_03840 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
CFDGDPAD_03841 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
CFDGDPAD_03842 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
CFDGDPAD_03843 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
CFDGDPAD_03844 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
CFDGDPAD_03845 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
CFDGDPAD_03846 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
CFDGDPAD_03847 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CFDGDPAD_03848 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
CFDGDPAD_03849 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
CFDGDPAD_03850 2.17e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
CFDGDPAD_03858 3.99e-96 - - - J - - - Acetyltransferase (GNAT) domain
CFDGDPAD_03859 2.01e-58 - - - - - - - -
CFDGDPAD_03860 1.08e-176 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CFDGDPAD_03861 8.9e-46 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
CFDGDPAD_03862 1.54e-55 - - - - - - - -
CFDGDPAD_03863 2.25e-232 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
CFDGDPAD_03864 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
CFDGDPAD_03865 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
CFDGDPAD_03866 1.14e-180 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CFDGDPAD_03867 2.97e-211 - - - K - - - AraC-like ligand binding domain
CFDGDPAD_03868 3.09e-218 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CFDGDPAD_03869 1.19e-101 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
CFDGDPAD_03870 1.19e-95 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
CFDGDPAD_03871 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CFDGDPAD_03872 1.6e-274 ydeG - - EGP - - - Major facilitator superfamily
CFDGDPAD_03873 9.2e-70 ydeH - - - - - - -
CFDGDPAD_03874 6.99e-136 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
CFDGDPAD_03875 8.57e-141 - - - - - - - -
CFDGDPAD_03876 1.69e-41 - - - S - - - SNARE associated Golgi protein
CFDGDPAD_03877 1.64e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
CFDGDPAD_03878 4.22e-111 - - - K - - - Transcriptional regulator C-terminal region
CFDGDPAD_03879 4.66e-197 ydeK - - EG - - - -transporter
CFDGDPAD_03880 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CFDGDPAD_03881 1.06e-96 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
CFDGDPAD_03882 3.37e-135 - - - S ko:K07002 - ko00000 Serine hydrolase
CFDGDPAD_03883 2.13e-74 - - - K - - - HxlR-like helix-turn-helix
CFDGDPAD_03884 3.96e-195 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
CFDGDPAD_03885 5.03e-91 ydeP - - K - - - Transcriptional regulator
CFDGDPAD_03886 1e-144 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
CFDGDPAD_03887 9.71e-258 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
CFDGDPAD_03888 1.78e-134 ydeS - - K - - - Transcriptional regulator
CFDGDPAD_03889 2.11e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
CFDGDPAD_03890 3.53e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CFDGDPAD_03891 1.28e-187 - - - J - - - GNAT acetyltransferase
CFDGDPAD_03892 1.09e-200 - - - EG - - - EamA-like transporter family
CFDGDPAD_03893 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CFDGDPAD_03894 9.91e-150 ydfE - - S - - - Flavin reductase like domain
CFDGDPAD_03895 1.5e-158 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
CFDGDPAD_03896 1.12e-103 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CFDGDPAD_03898 7.24e-247 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFDGDPAD_03899 2.69e-141 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFDGDPAD_03900 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
CFDGDPAD_03901 3.8e-223 - - - S - - - Alpha/beta hydrolase family
CFDGDPAD_03902 2.27e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
CFDGDPAD_03903 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
CFDGDPAD_03904 2.59e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFDGDPAD_03905 7.8e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
CFDGDPAD_03906 4.51e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
CFDGDPAD_03907 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
CFDGDPAD_03908 8.92e-73 ydfQ - - CO - - - Thioredoxin
CFDGDPAD_03909 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
CFDGDPAD_03910 5.33e-39 - - - - - - - -
CFDGDPAD_03912 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
CFDGDPAD_03913 2.57e-159 ydfS - - S - - - Protein of unknown function (DUF421)
CFDGDPAD_03914 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
CFDGDPAD_03915 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
CFDGDPAD_03916 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
CFDGDPAD_03917 1.35e-124 ydgC - - K - - - Bacterial regulatory proteins, tetR family
CFDGDPAD_03918 2.85e-70 - - - S - - - DoxX-like family
CFDGDPAD_03919 4.14e-113 yycN - - K - - - Acetyltransferase
CFDGDPAD_03920 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
CFDGDPAD_03921 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
CFDGDPAD_03922 5.94e-118 - - - S - - - DinB family
CFDGDPAD_03923 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
CFDGDPAD_03924 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
CFDGDPAD_03925 7.5e-146 ydgI - - C - - - nitroreductase
CFDGDPAD_03926 3.29e-90 - - - K - - - Winged helix DNA-binding domain
CFDGDPAD_03927 1.99e-265 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
CFDGDPAD_03928 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
CFDGDPAD_03929 4.31e-157 ydhC - - K - - - FCD
CFDGDPAD_03930 5.16e-309 ydhD - - M - - - Glycosyl hydrolase
CFDGDPAD_03931 1.86e-287 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CFDGDPAD_03932 1.18e-160 - - - - - - - -
CFDGDPAD_03933 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
CFDGDPAD_03934 3.33e-89 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
CFDGDPAD_03936 1.73e-106 - - - K - - - Acetyltransferase (GNAT) domain
CFDGDPAD_03937 3.28e-232 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
CFDGDPAD_03938 1.57e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
CFDGDPAD_03939 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
CFDGDPAD_03940 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CFDGDPAD_03941 3.39e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CFDGDPAD_03942 2.27e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CFDGDPAD_03943 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CFDGDPAD_03944 7.75e-171 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
CFDGDPAD_03945 4.06e-213 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
CFDGDPAD_03946 5.09e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
CFDGDPAD_03947 6.49e-269 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
CFDGDPAD_03948 3.44e-202 ydhU - - P ko:K07217 - ko00000 Catalase
CFDGDPAD_03951 1.93e-122 - - GH19 M ko:K03791 - ko00000 Lysin motif
CFDGDPAD_03952 4.12e-73 - - - - - - - -
CFDGDPAD_03953 2.18e-269 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CFDGDPAD_03954 4.14e-229 mpr - - M - - - Belongs to the peptidase S1B family
CFDGDPAD_03956 4.76e-215 - - - S - - - Alpha/beta hydrolase family
CFDGDPAD_03957 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFDGDPAD_03958 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
CFDGDPAD_03959 3.41e-187 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
CFDGDPAD_03960 2.42e-58 ybfN - - - - - - -
CFDGDPAD_03961 1.24e-09 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
CFDGDPAD_03962 1.36e-243 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
CFDGDPAD_03963 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CFDGDPAD_03964 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CFDGDPAD_03965 1.82e-175 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CFDGDPAD_03966 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
CFDGDPAD_03968 6.2e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
CFDGDPAD_03969 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
CFDGDPAD_03970 8.72e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
CFDGDPAD_03971 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
CFDGDPAD_03972 3.06e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
CFDGDPAD_03973 2.05e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
CFDGDPAD_03974 7.01e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
CFDGDPAD_03975 3.37e-221 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
CFDGDPAD_03976 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CFDGDPAD_03977 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
CFDGDPAD_03978 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
CFDGDPAD_03979 2.3e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
CFDGDPAD_03980 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
CFDGDPAD_03981 3.01e-223 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
CFDGDPAD_03982 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
CFDGDPAD_03983 6.19e-214 eamA1 - - EG - - - spore germination
CFDGDPAD_03984 3.18e-161 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDGDPAD_03985 6.48e-216 ycbM - - T - - - Histidine kinase
CFDGDPAD_03986 1.31e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
CFDGDPAD_03987 6.75e-147 - - - S - - - ABC-2 family transporter protein
CFDGDPAD_03988 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
CFDGDPAD_03989 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
CFDGDPAD_03990 4.66e-175 ycbR - - T - - - vWA found in TerF C terminus
CFDGDPAD_03991 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
CFDGDPAD_03992 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CFDGDPAD_03993 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFDGDPAD_03994 2.42e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CFDGDPAD_03995 4.17e-260 ycbU - - E - - - Selenocysteine lyase
CFDGDPAD_03996 2.87e-308 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
CFDGDPAD_03997 6.54e-132 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
CFDGDPAD_03998 3.56e-259 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
CFDGDPAD_03999 6.75e-139 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
CFDGDPAD_04000 2.69e-72 - - - S - - - RDD family
CFDGDPAD_04001 1.18e-253 yccF - - K ko:K07039 - ko00000 SEC-C motif
CFDGDPAD_04002 1.52e-213 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
CFDGDPAD_04003 2.79e-162 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
CFDGDPAD_04004 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
CFDGDPAD_04005 1.62e-256 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
CFDGDPAD_04006 2.38e-222 yccK - - C - - - Aldo keto reductase
CFDGDPAD_04007 1.92e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
CFDGDPAD_04008 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CFDGDPAD_04009 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CFDGDPAD_04010 2.27e-124 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
CFDGDPAD_04011 1.42e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
CFDGDPAD_04012 2.79e-179 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
CFDGDPAD_04013 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
CFDGDPAD_04014 2.27e-220 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
CFDGDPAD_04015 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
CFDGDPAD_04016 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
CFDGDPAD_04017 9.18e-242 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFDGDPAD_04018 3.08e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
CFDGDPAD_04019 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
CFDGDPAD_04020 2.87e-137 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
CFDGDPAD_04021 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
CFDGDPAD_04022 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
CFDGDPAD_04023 2.96e-245 yceH - - P - - - Belongs to the TelA family
CFDGDPAD_04024 7.75e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
CFDGDPAD_04025 3.06e-263 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
CFDGDPAD_04026 1.97e-60 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
CFDGDPAD_04027 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
CFDGDPAD_04028 6.02e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
CFDGDPAD_04029 1.16e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
CFDGDPAD_04030 1.97e-276 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
CFDGDPAD_04031 0.0 ycgA - - S - - - Membrane
CFDGDPAD_04032 2.72e-105 ycgB - - - - - - -
CFDGDPAD_04033 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
CFDGDPAD_04034 4.85e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
CFDGDPAD_04035 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
CFDGDPAD_04036 0.0 mdr - - EGP - - - the major facilitator superfamily
CFDGDPAD_04037 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
CFDGDPAD_04038 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
CFDGDPAD_04039 2.33e-189 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
CFDGDPAD_04040 0.0 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
CFDGDPAD_04041 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
CFDGDPAD_04042 5.24e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CFDGDPAD_04043 2.54e-138 tmrB - - S - - - AAA domain
CFDGDPAD_04045 8.64e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFDGDPAD_04046 1.29e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
CFDGDPAD_04047 1.88e-226 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
CFDGDPAD_04048 6.64e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
CFDGDPAD_04049 7.76e-187 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
CFDGDPAD_04050 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
CFDGDPAD_04051 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
CFDGDPAD_04052 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CFDGDPAD_04053 1.12e-287 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
CFDGDPAD_04054 1.1e-194 ycgQ - - S ko:K08986 - ko00000 membrane
CFDGDPAD_04055 2.41e-184 ycgR - - S ko:K07089 - ko00000 permeases
CFDGDPAD_04056 5.47e-199 ycgS - - I - - - alpha/beta hydrolase fold
CFDGDPAD_04057 5.08e-237 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
CFDGDPAD_04058 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
CFDGDPAD_04059 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
CFDGDPAD_04060 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CFDGDPAD_04061 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CFDGDPAD_04062 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
CFDGDPAD_04063 9.13e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
CFDGDPAD_04064 1.22e-221 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
CFDGDPAD_04065 3.14e-130 - - - M - - - ErfK YbiS YcfS YnhG
CFDGDPAD_04066 1.12e-289 yciC - - S - - - GTPases (G3E family)
CFDGDPAD_04067 1.22e-148 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
CFDGDPAD_04068 1.53e-186 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
CFDGDPAD_04070 1.33e-60 yckC - - S - - - membrane
CFDGDPAD_04071 1.01e-68 yckD - - S - - - Protein of unknown function (DUF2680)
CFDGDPAD_04072 7.43e-58 - - - K - - - MarR family
CFDGDPAD_04073 9e-32 - - - - - - - -
CFDGDPAD_04074 1.16e-154 - - - S - - - AAA domain
CFDGDPAD_04075 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
CFDGDPAD_04076 2.77e-90 nin - - S - - - Competence protein J (ComJ)
CFDGDPAD_04077 1.13e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
CFDGDPAD_04078 1.86e-268 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
CFDGDPAD_04079 1.32e-125 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
CFDGDPAD_04080 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
CFDGDPAD_04081 6.05e-86 hxlR - - K - - - transcriptional
CFDGDPAD_04082 2.61e-316 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
CFDGDPAD_04084 1.08e-202 ybaS - - S - - - Na -dependent transporter
CFDGDPAD_04085 1.24e-178 ybbA - - S ko:K07017 - ko00000 Putative esterase
CFDGDPAD_04086 1.01e-227 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDGDPAD_04087 2.88e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDGDPAD_04088 5.12e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
CFDGDPAD_04089 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
CFDGDPAD_04090 2.33e-302 ybbC - - S - - - protein conserved in bacteria
CFDGDPAD_04091 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
CFDGDPAD_04092 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
CFDGDPAD_04093 8.5e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
CFDGDPAD_04094 1.82e-192 ybbH - - K - - - transcriptional
CFDGDPAD_04095 3.87e-209 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CFDGDPAD_04096 3.13e-114 ybbJ - - J - - - acetyltransferase
CFDGDPAD_04097 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
CFDGDPAD_04103 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
CFDGDPAD_04104 2.63e-150 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
CFDGDPAD_04105 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CFDGDPAD_04106 1.44e-290 ybbR - - S - - - protein conserved in bacteria
CFDGDPAD_04107 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFDGDPAD_04108 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CFDGDPAD_04109 1.96e-222 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CFDGDPAD_04110 2.16e-155 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
CFDGDPAD_04111 2.14e-128 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CFDGDPAD_04112 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
CFDGDPAD_04113 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
CFDGDPAD_04114 1.63e-121 ybcF - - P - - - carbonic anhydrase
CFDGDPAD_04115 5.59e-64 - - - - - - - -
CFDGDPAD_04116 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
CFDGDPAD_04117 9.45e-67 - - - K - - - Helix-turn-helix domain
CFDGDPAD_04118 1.14e-258 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
CFDGDPAD_04119 7.97e-73 - - - - - - - -
CFDGDPAD_04120 2.31e-232 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CFDGDPAD_04121 1.39e-157 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
CFDGDPAD_04122 4.22e-214 - - - T - - - His Kinase A (phospho-acceptor) domain
CFDGDPAD_04124 1.68e-179 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
CFDGDPAD_04125 1.82e-193 ybdN - - - - - - -
CFDGDPAD_04126 4.65e-276 ybdO - - S - - - Domain of unknown function (DUF4885)
CFDGDPAD_04127 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
CFDGDPAD_04128 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
CFDGDPAD_04129 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
CFDGDPAD_04130 8.74e-192 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
CFDGDPAD_04131 2.2e-313 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
CFDGDPAD_04132 1.11e-54 ybyB - - - - - - -
CFDGDPAD_04133 0.0 ybeC - - E - - - amino acid
CFDGDPAD_04134 7.3e-213 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
CFDGDPAD_04135 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
CFDGDPAD_04136 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
CFDGDPAD_04137 1.48e-218 ybfA - - K - - - FR47-like protein
CFDGDPAD_04138 4.36e-283 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
CFDGDPAD_04139 1.19e-204 ybfH - - EG - - - EamA-like transporter family
CFDGDPAD_04140 2.12e-187 ybfI - - K - - - AraC-like ligand binding domain
CFDGDPAD_04141 1.27e-43 - - - K - - - sigma factor activity
CFDGDPAD_04142 2.73e-28 xhlB - - S - - - SPP1 phage holin
CFDGDPAD_04143 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
CFDGDPAD_04144 3.44e-132 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
CFDGDPAD_04145 1.04e-122 gerD - - - ko:K06294 - ko00000 -
CFDGDPAD_04146 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
CFDGDPAD_04147 9.05e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
CFDGDPAD_04148 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
CFDGDPAD_04149 6.15e-186 ybaJ - - Q - - - Methyltransferase domain
CFDGDPAD_04150 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
CFDGDPAD_04151 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFDGDPAD_04152 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CFDGDPAD_04153 3.23e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFDGDPAD_04154 4.47e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFDGDPAD_04155 7.5e-200 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFDGDPAD_04156 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
CFDGDPAD_04157 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFDGDPAD_04158 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFDGDPAD_04159 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFDGDPAD_04160 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
CFDGDPAD_04161 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFDGDPAD_04162 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
CFDGDPAD_04163 1.46e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CFDGDPAD_04164 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CFDGDPAD_04165 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
CFDGDPAD_04166 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
CFDGDPAD_04167 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFDGDPAD_04168 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFDGDPAD_04169 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFDGDPAD_04170 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFDGDPAD_04171 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFDGDPAD_04172 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFDGDPAD_04173 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFDGDPAD_04174 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFDGDPAD_04175 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFDGDPAD_04176 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
CFDGDPAD_04177 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFDGDPAD_04178 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFDGDPAD_04179 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFDGDPAD_04180 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFDGDPAD_04181 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFDGDPAD_04182 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CFDGDPAD_04183 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
CFDGDPAD_04184 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFDGDPAD_04185 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
CFDGDPAD_04186 3.16e-231 ybaC - - S - - - Alpha/beta hydrolase family
CFDGDPAD_04187 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFDGDPAD_04188 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFDGDPAD_04189 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CFDGDPAD_04190 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFDGDPAD_04191 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
CFDGDPAD_04192 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFDGDPAD_04193 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFDGDPAD_04194 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
CFDGDPAD_04195 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CFDGDPAD_04196 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFDGDPAD_04197 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CFDGDPAD_04198 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFDGDPAD_04199 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
CFDGDPAD_04200 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CFDGDPAD_04201 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
CFDGDPAD_04202 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
CFDGDPAD_04203 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFDGDPAD_04204 2.04e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CFDGDPAD_04205 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
CFDGDPAD_04206 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
CFDGDPAD_04207 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFDGDPAD_04208 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
CFDGDPAD_04209 2.13e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
CFDGDPAD_04210 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
CFDGDPAD_04211 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CFDGDPAD_04212 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CFDGDPAD_04213 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
CFDGDPAD_04214 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
CFDGDPAD_04215 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
CFDGDPAD_04216 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
CFDGDPAD_04217 1.82e-41 csfB - - S - - - Inhibitor of sigma-G Gin
CFDGDPAD_04218 1.82e-130 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
CFDGDPAD_04219 3.4e-258 yaaN - - P - - - Belongs to the TelA family
CFDGDPAD_04220 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
CFDGDPAD_04221 1.34e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFDGDPAD_04222 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
CFDGDPAD_04223 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
CFDGDPAD_04224 2.42e-236 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
CFDGDPAD_04225 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
CFDGDPAD_04226 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
CFDGDPAD_04227 1.14e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
CFDGDPAD_04228 2.43e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
CFDGDPAD_04229 2.43e-206 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CFDGDPAD_04230 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
CFDGDPAD_04231 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFDGDPAD_04232 1.19e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
CFDGDPAD_04233 1.91e-283 yabE - - T - - - protein conserved in bacteria
CFDGDPAD_04234 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CFDGDPAD_04235 1.68e-197 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CFDGDPAD_04236 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
CFDGDPAD_04237 5.32e-53 veg - - S - - - protein conserved in bacteria
CFDGDPAD_04238 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CFDGDPAD_04239 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
CFDGDPAD_04240 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
CFDGDPAD_04241 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
CFDGDPAD_04242 6.06e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFDGDPAD_04243 1.43e-222 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFDGDPAD_04244 4.16e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CFDGDPAD_04245 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CFDGDPAD_04246 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
CFDGDPAD_04247 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFDGDPAD_04248 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
CFDGDPAD_04249 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CFDGDPAD_04250 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
CFDGDPAD_04251 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
CFDGDPAD_04252 1.91e-66 yabP - - S - - - Sporulation protein YabP
CFDGDPAD_04253 4.28e-137 yabQ - - S - - - spore cortex biosynthesis protein
CFDGDPAD_04254 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
CFDGDPAD_04255 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
CFDGDPAD_04258 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
CFDGDPAD_04259 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
CFDGDPAD_04260 4.67e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
CFDGDPAD_04261 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CFDGDPAD_04262 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
CFDGDPAD_04263 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFDGDPAD_04264 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CFDGDPAD_04265 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CFDGDPAD_04266 2.72e-195 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
CFDGDPAD_04267 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
CFDGDPAD_04268 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFDGDPAD_04269 1.72e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
CFDGDPAD_04270 1.54e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
CFDGDPAD_04271 7.82e-204 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFDGDPAD_04272 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CFDGDPAD_04273 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFDGDPAD_04274 1.81e-41 yazB - - K - - - transcriptional
CFDGDPAD_04275 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFDGDPAD_04276 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
CFDGDPAD_04277 2.6e-233 yaaC - - S - - - YaaC-like Protein
CFDGDPAD_04278 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CFDGDPAD_04279 7.51e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
CFDGDPAD_04280 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CFDGDPAD_04281 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CFDGDPAD_04282 3.98e-295 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFDGDPAD_04284 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
CFDGDPAD_04285 3.88e-147 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
CFDGDPAD_04286 2.11e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
CFDGDPAD_04287 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
CFDGDPAD_04288 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CFDGDPAD_04289 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFDGDPAD_04290 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CFDGDPAD_04291 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFDGDPAD_04292 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
CFDGDPAD_04293 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
CFDGDPAD_04294 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDGDPAD_04295 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDGDPAD_04300 2.4e-76 - - - - - - - -
CFDGDPAD_04302 8.73e-256 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
CFDGDPAD_04303 3.42e-55 - - - - - - - -
CFDGDPAD_04305 1.86e-23 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
CFDGDPAD_04307 1.92e-40 - - - - - - - -
CFDGDPAD_04309 2.65e-21 - - - - - - - -
CFDGDPAD_04310 2.22e-155 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
CFDGDPAD_04311 1.6e-71 - - - K - - - DNA binding
CFDGDPAD_04314 4.98e-35 - - - - - - - -
CFDGDPAD_04317 1.32e-10 - - - L - - - Phage integrase family
CFDGDPAD_04320 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDGDPAD_04321 3.08e-283 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDGDPAD_04325 1.13e-249 - - - L - - - Replication protein
CFDGDPAD_04326 1.08e-135 rapE - - S ko:K06363 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
CFDGDPAD_04328 1.66e-97 - - - K - - - Transcriptional regulator
CFDGDPAD_04329 1.28e-290 pre - - D - - - plasmid recombination enzyme
CFDGDPAD_04330 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
CFDGDPAD_04339 7.11e-10 - - - - - - - -

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)