ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NOGEOMFM_00001 5.55e-301 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NOGEOMFM_00002 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NOGEOMFM_00003 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
NOGEOMFM_00004 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NOGEOMFM_00005 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
NOGEOMFM_00006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NOGEOMFM_00007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NOGEOMFM_00008 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NOGEOMFM_00011 2.14e-232 yaaC - - S - - - YaaC-like Protein
NOGEOMFM_00012 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NOGEOMFM_00013 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NOGEOMFM_00014 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NOGEOMFM_00015 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NOGEOMFM_00016 6.6e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NOGEOMFM_00018 2.15e-158 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
NOGEOMFM_00019 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
NOGEOMFM_00020 2.99e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
NOGEOMFM_00021 1.89e-123 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
NOGEOMFM_00022 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NOGEOMFM_00023 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NOGEOMFM_00024 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NOGEOMFM_00025 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NOGEOMFM_00026 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
NOGEOMFM_00027 6.2e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
NOGEOMFM_00028 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NOGEOMFM_00031 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
NOGEOMFM_00032 3.28e-133 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NOGEOMFM_00033 8.37e-259 yaaN - - P - - - Belongs to the TelA family
NOGEOMFM_00034 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
NOGEOMFM_00035 2.82e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NOGEOMFM_00036 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
NOGEOMFM_00037 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
NOGEOMFM_00038 2.42e-236 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NOGEOMFM_00039 1.1e-189 yaaT - - S - - - stage 0 sporulation protein
NOGEOMFM_00040 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
NOGEOMFM_00041 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
NOGEOMFM_00042 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
NOGEOMFM_00043 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NOGEOMFM_00044 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
NOGEOMFM_00045 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NOGEOMFM_00046 4.85e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
NOGEOMFM_00047 1.18e-277 yabE - - T - - - protein conserved in bacteria
NOGEOMFM_00048 1.43e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NOGEOMFM_00049 5.04e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NOGEOMFM_00050 1.84e-197 yabG - - S ko:K06436 - ko00000 peptidase
NOGEOMFM_00051 5.32e-53 veg - - S - - - protein conserved in bacteria
NOGEOMFM_00052 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
NOGEOMFM_00053 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NOGEOMFM_00054 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NOGEOMFM_00055 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
NOGEOMFM_00056 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NOGEOMFM_00057 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NOGEOMFM_00058 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NOGEOMFM_00059 9.8e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NOGEOMFM_00060 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NOGEOMFM_00061 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
NOGEOMFM_00062 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NOGEOMFM_00063 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
NOGEOMFM_00064 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NOGEOMFM_00065 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NOGEOMFM_00066 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NOGEOMFM_00067 1.91e-66 yabP - - S - - - Sporulation protein YabP
NOGEOMFM_00068 2.21e-139 yabQ - - S - - - spore cortex biosynthesis protein
NOGEOMFM_00069 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NOGEOMFM_00070 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NOGEOMFM_00073 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
NOGEOMFM_00074 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NOGEOMFM_00075 1.63e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
NOGEOMFM_00076 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NOGEOMFM_00077 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
NOGEOMFM_00078 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NOGEOMFM_00079 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NOGEOMFM_00080 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NOGEOMFM_00081 2.72e-195 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
NOGEOMFM_00082 1.26e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NOGEOMFM_00083 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NOGEOMFM_00084 1.72e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
NOGEOMFM_00085 1.54e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
NOGEOMFM_00086 1.11e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NOGEOMFM_00087 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NOGEOMFM_00088 9.21e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NOGEOMFM_00089 1.81e-41 yazB - - K - - - transcriptional
NOGEOMFM_00090 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NOGEOMFM_00091 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NOGEOMFM_00092 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NOGEOMFM_00102 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NOGEOMFM_00103 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NOGEOMFM_00104 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
NOGEOMFM_00105 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NOGEOMFM_00106 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
NOGEOMFM_00107 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NOGEOMFM_00108 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NOGEOMFM_00109 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
NOGEOMFM_00110 4.29e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NOGEOMFM_00111 2.59e-112 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NOGEOMFM_00112 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NOGEOMFM_00113 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
NOGEOMFM_00114 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NOGEOMFM_00115 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NOGEOMFM_00116 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NOGEOMFM_00117 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
NOGEOMFM_00118 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
NOGEOMFM_00119 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NOGEOMFM_00120 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NOGEOMFM_00121 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NOGEOMFM_00122 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NOGEOMFM_00123 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NOGEOMFM_00124 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NOGEOMFM_00125 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
NOGEOMFM_00126 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NOGEOMFM_00127 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NOGEOMFM_00128 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
NOGEOMFM_00129 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NOGEOMFM_00130 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NOGEOMFM_00131 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NOGEOMFM_00132 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NOGEOMFM_00133 8.68e-229 ybaC - - S - - - Alpha/beta hydrolase family
NOGEOMFM_00134 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NOGEOMFM_00135 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NOGEOMFM_00136 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NOGEOMFM_00137 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NOGEOMFM_00138 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NOGEOMFM_00139 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NOGEOMFM_00140 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NOGEOMFM_00141 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NOGEOMFM_00142 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NOGEOMFM_00143 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NOGEOMFM_00144 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NOGEOMFM_00145 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NOGEOMFM_00146 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NOGEOMFM_00147 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NOGEOMFM_00148 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NOGEOMFM_00149 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NOGEOMFM_00150 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NOGEOMFM_00151 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NOGEOMFM_00152 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NOGEOMFM_00153 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NOGEOMFM_00154 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NOGEOMFM_00155 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NOGEOMFM_00156 1.46e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NOGEOMFM_00157 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NOGEOMFM_00158 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NOGEOMFM_00159 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NOGEOMFM_00160 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NOGEOMFM_00161 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NOGEOMFM_00162 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NOGEOMFM_00163 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NOGEOMFM_00164 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NOGEOMFM_00165 1.28e-195 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NOGEOMFM_00166 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NOGEOMFM_00167 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NOGEOMFM_00168 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NOGEOMFM_00169 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NOGEOMFM_00170 2.14e-186 ybaJ - - Q - - - Methyltransferase domain
NOGEOMFM_00171 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
NOGEOMFM_00172 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NOGEOMFM_00173 4.47e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NOGEOMFM_00174 1.04e-122 gerD - - - ko:K06294 - ko00000 -
NOGEOMFM_00175 2.42e-132 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
NOGEOMFM_00176 2.49e-180 pdaB - - G - - - Polysaccharide deacetylase
NOGEOMFM_00177 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NOGEOMFM_00184 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NOGEOMFM_00185 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NOGEOMFM_00186 2.61e-316 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NOGEOMFM_00188 5.36e-203 ybaS - - S - - - Na -dependent transporter
NOGEOMFM_00189 5.87e-177 ybbA - - S ko:K07017 - ko00000 Putative esterase
NOGEOMFM_00190 2.37e-226 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NOGEOMFM_00191 1.17e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NOGEOMFM_00192 1.26e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
NOGEOMFM_00193 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
NOGEOMFM_00194 8.14e-303 ybbC - - S - - - protein conserved in bacteria
NOGEOMFM_00195 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
NOGEOMFM_00196 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
NOGEOMFM_00197 1.04e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NOGEOMFM_00198 3.01e-191 ybbH - - K - - - transcriptional
NOGEOMFM_00199 1.11e-208 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NOGEOMFM_00200 1.81e-113 ybbJ - - J - - - acetyltransferase
NOGEOMFM_00201 4.19e-101 ybbK - - S - - - Protein of unknown function (DUF523)
NOGEOMFM_00207 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NOGEOMFM_00208 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NOGEOMFM_00209 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NOGEOMFM_00210 3.41e-291 ybbR - - S - - - protein conserved in bacteria
NOGEOMFM_00211 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NOGEOMFM_00212 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NOGEOMFM_00213 5.38e-220 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NOGEOMFM_00214 1.71e-152 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
NOGEOMFM_00215 1.06e-128 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NOGEOMFM_00216 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NOGEOMFM_00217 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
NOGEOMFM_00218 1.83e-118 ybcF - - P - - - carbonic anhydrase
NOGEOMFM_00219 1.6e-63 - - - - - - - -
NOGEOMFM_00220 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
NOGEOMFM_00222 9.45e-67 - - - K - - - Helix-turn-helix domain
NOGEOMFM_00223 1.81e-255 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
NOGEOMFM_00225 1.21e-21 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NOGEOMFM_00226 7.04e-139 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
NOGEOMFM_00227 6.48e-50 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C family protein
NOGEOMFM_00229 6.47e-176 abcA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NOGEOMFM_00230 2.31e-232 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NOGEOMFM_00231 3.28e-156 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
NOGEOMFM_00232 1.61e-218 - - - T - - - His Kinase A (phospho-acceptor) domain
NOGEOMFM_00234 3.26e-177 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
NOGEOMFM_00235 7.4e-193 ybdN - - - - - - -
NOGEOMFM_00236 1.22e-271 ybdO - - S - - - Domain of unknown function (DUF4885)
NOGEOMFM_00237 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NOGEOMFM_00238 5.46e-51 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
NOGEOMFM_00239 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
NOGEOMFM_00240 1.06e-192 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
NOGEOMFM_00241 3.64e-312 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
NOGEOMFM_00242 1.11e-54 ybyB - - - - - - -
NOGEOMFM_00243 0.0 ybeC - - E - - - amino acid
NOGEOMFM_00244 2.85e-210 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
NOGEOMFM_00245 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
NOGEOMFM_00246 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
NOGEOMFM_00247 2.1e-218 ybfA - - K - - - FR47-like protein
NOGEOMFM_00248 2.75e-286 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
NOGEOMFM_00250 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
NOGEOMFM_00251 5.27e-208 ybfH - - EG - - - EamA-like transporter family
NOGEOMFM_00252 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
NOGEOMFM_00253 5.85e-274 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NOGEOMFM_00254 5.04e-230 mpr - - M - - - Belongs to the peptidase S1B family
NOGEOMFM_00256 2.02e-216 - - - S - - - Alpha/beta hydrolase family
NOGEOMFM_00257 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NOGEOMFM_00258 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
NOGEOMFM_00259 4.33e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NOGEOMFM_00260 1.58e-59 ybfN - - - - - - -
NOGEOMFM_00261 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
NOGEOMFM_00262 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NOGEOMFM_00263 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NOGEOMFM_00264 2.59e-175 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NOGEOMFM_00265 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
NOGEOMFM_00267 2.82e-260 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NOGEOMFM_00268 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NOGEOMFM_00269 5.26e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
NOGEOMFM_00270 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NOGEOMFM_00271 9.16e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NOGEOMFM_00272 3.55e-294 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NOGEOMFM_00273 1.72e-217 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
NOGEOMFM_00274 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
NOGEOMFM_00275 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NOGEOMFM_00276 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NOGEOMFM_00277 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NOGEOMFM_00278 4.63e-161 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
NOGEOMFM_00279 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
NOGEOMFM_00280 2.47e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
NOGEOMFM_00281 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
NOGEOMFM_00282 7.31e-218 eamA1 - - EG - - - spore germination
NOGEOMFM_00283 3.71e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NOGEOMFM_00284 6.21e-214 ycbM - - T - - - Histidine kinase
NOGEOMFM_00285 1.66e-216 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_00286 2.87e-148 - - - S - - - ABC-2 family transporter protein
NOGEOMFM_00287 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
NOGEOMFM_00288 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
NOGEOMFM_00289 5.44e-174 ycbR - - T - - - vWA found in TerF C terminus
NOGEOMFM_00290 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
NOGEOMFM_00291 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NOGEOMFM_00292 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NOGEOMFM_00293 9.85e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NOGEOMFM_00294 4.86e-259 ycbU - - E - - - Selenocysteine lyase
NOGEOMFM_00295 2.51e-302 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
NOGEOMFM_00296 1.88e-131 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NOGEOMFM_00297 1.97e-256 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NOGEOMFM_00298 1.63e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NOGEOMFM_00299 4.32e-78 - - - S - - - RDD family
NOGEOMFM_00300 1.01e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
NOGEOMFM_00301 1.77e-212 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NOGEOMFM_00302 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NOGEOMFM_00303 2.2e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NOGEOMFM_00304 5.64e-257 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NOGEOMFM_00305 6.81e-222 yccK - - C - - - Aldo keto reductase
NOGEOMFM_00306 1.35e-241 ycdA - - S - - - Domain of unknown function (DUF5105)
NOGEOMFM_00307 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NOGEOMFM_00308 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NOGEOMFM_00309 2.65e-123 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NOGEOMFM_00310 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
NOGEOMFM_00311 1.96e-179 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
NOGEOMFM_00312 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NOGEOMFM_00313 2.27e-220 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NOGEOMFM_00314 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NOGEOMFM_00315 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NOGEOMFM_00316 5.95e-238 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NOGEOMFM_00317 2.17e-140 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
NOGEOMFM_00318 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NOGEOMFM_00319 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
NOGEOMFM_00320 1.37e-174 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
NOGEOMFM_00321 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
NOGEOMFM_00322 2.96e-245 yceH - - P - - - Belongs to the TelA family
NOGEOMFM_00323 3.84e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
NOGEOMFM_00324 1.3e-264 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
NOGEOMFM_00325 1.97e-60 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NOGEOMFM_00326 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
NOGEOMFM_00327 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NOGEOMFM_00328 1.16e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
NOGEOMFM_00329 1.97e-276 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
NOGEOMFM_00330 0.0 ycgA - - S - - - Membrane
NOGEOMFM_00331 2.72e-105 ycgB - - - - - - -
NOGEOMFM_00332 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
NOGEOMFM_00333 9.79e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NOGEOMFM_00334 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NOGEOMFM_00335 0.0 mdr - - EGP - - - the major facilitator superfamily
NOGEOMFM_00336 3.7e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
NOGEOMFM_00337 6.42e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
NOGEOMFM_00338 2.07e-192 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
NOGEOMFM_00339 9.32e-317 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NOGEOMFM_00340 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
NOGEOMFM_00341 5.24e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NOGEOMFM_00342 1.43e-53 tmrB - - S - - - AAA domain
NOGEOMFM_00343 2.39e-22 tmrB - - S - - - AAA domain
NOGEOMFM_00345 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NOGEOMFM_00346 1.02e-183 - - - Q - - - ubiE/COQ5 methyltransferase family
NOGEOMFM_00347 5.4e-226 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
NOGEOMFM_00348 3.16e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
NOGEOMFM_00349 1.75e-183 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
NOGEOMFM_00350 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NOGEOMFM_00351 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NOGEOMFM_00352 2.64e-316 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NOGEOMFM_00353 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
NOGEOMFM_00354 7.72e-195 ycgQ - - S ko:K08986 - ko00000 membrane
NOGEOMFM_00355 2.41e-184 ycgR - - S ko:K07089 - ko00000 permeases
NOGEOMFM_00356 2.32e-200 ycgS - - I - - - alpha/beta hydrolase fold
NOGEOMFM_00357 1.48e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NOGEOMFM_00358 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NOGEOMFM_00359 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
NOGEOMFM_00360 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NOGEOMFM_00361 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NOGEOMFM_00362 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
NOGEOMFM_00363 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NOGEOMFM_00364 1.08e-215 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
NOGEOMFM_00365 1.04e-140 - - - M - - - ErfK YbiS YcfS YnhG
NOGEOMFM_00366 3.76e-288 yciC - - S - - - GTPases (G3E family)
NOGEOMFM_00367 9.69e-149 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NOGEOMFM_00368 7.26e-185 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NOGEOMFM_00371 1.29e-95 yckC - - S - - - membrane
NOGEOMFM_00372 1.01e-68 yckD - - S - - - Protein of unknown function (DUF2680)
NOGEOMFM_00373 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NOGEOMFM_00374 4.78e-91 nin - - S - - - Competence protein J (ComJ)
NOGEOMFM_00375 3.23e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
NOGEOMFM_00376 1.86e-268 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NOGEOMFM_00377 1.13e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
NOGEOMFM_00378 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
NOGEOMFM_00379 6.05e-86 hxlR - - K - - - transcriptional
NOGEOMFM_00380 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NOGEOMFM_00381 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NOGEOMFM_00382 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
NOGEOMFM_00383 2.71e-178 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
NOGEOMFM_00384 6.53e-290 - - - EGP - - - Major Facilitator Superfamily
NOGEOMFM_00385 2.87e-120 - - - S - - - YcxB-like protein
NOGEOMFM_00386 7.69e-204 ycxC - - EG - - - EamA-like transporter family
NOGEOMFM_00387 0.0 ycxD - - K - - - GntR family transcriptional regulator
NOGEOMFM_00388 2.02e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
NOGEOMFM_00389 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
NOGEOMFM_00390 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NOGEOMFM_00391 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NOGEOMFM_00392 2.49e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NOGEOMFM_00393 5.32e-209 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
NOGEOMFM_00394 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NOGEOMFM_00395 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NOGEOMFM_00396 9.86e-53 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
NOGEOMFM_00397 2.82e-105 yclD - - - - - - -
NOGEOMFM_00398 2.15e-199 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
NOGEOMFM_00399 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
NOGEOMFM_00400 0.0 yclG - - M - - - Pectate lyase superfamily protein
NOGEOMFM_00402 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
NOGEOMFM_00403 8.35e-297 gerKC - - S ko:K06297 - ko00000 spore germination
NOGEOMFM_00404 2.29e-254 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
NOGEOMFM_00405 2.05e-156 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NOGEOMFM_00406 2.27e-279 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
NOGEOMFM_00407 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NOGEOMFM_00408 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NOGEOMFM_00409 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NOGEOMFM_00411 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NOGEOMFM_00412 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NOGEOMFM_00413 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NOGEOMFM_00414 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NOGEOMFM_00415 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_00416 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
NOGEOMFM_00417 1.18e-96 - - - V - - - Restriction endonuclease
NOGEOMFM_00418 0.0 ycnB - - EGP - - - the major facilitator superfamily
NOGEOMFM_00419 5.87e-198 ycnC - - K - - - Transcriptional regulator
NOGEOMFM_00420 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NOGEOMFM_00421 1.68e-60 ycnE - - S - - - Monooxygenase
NOGEOMFM_00422 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NOGEOMFM_00423 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NOGEOMFM_00424 4.64e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NOGEOMFM_00425 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NOGEOMFM_00426 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
NOGEOMFM_00427 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NOGEOMFM_00428 3.99e-134 ycnI - - S - - - protein conserved in bacteria
NOGEOMFM_00429 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
NOGEOMFM_00430 1.22e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NOGEOMFM_00431 1.34e-74 - - - - - - - -
NOGEOMFM_00432 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
NOGEOMFM_00433 4.81e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NOGEOMFM_00434 8.5e-266 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
NOGEOMFM_00435 5.62e-254 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
NOGEOMFM_00437 7.47e-56 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NOGEOMFM_00438 1.71e-143 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
NOGEOMFM_00439 1.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
NOGEOMFM_00441 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
NOGEOMFM_00442 3.82e-181 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
NOGEOMFM_00443 1.87e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
NOGEOMFM_00444 7.45e-20 ycsI - - S - - - Belongs to the D-glutamate cyclase family
NOGEOMFM_00445 1.68e-144 ycsI - - S - - - Belongs to the D-glutamate cyclase family
NOGEOMFM_00446 5.04e-173 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
NOGEOMFM_00447 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
NOGEOMFM_00448 3.8e-171 kipR - - K - - - Transcriptional regulator
NOGEOMFM_00449 4.18e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
NOGEOMFM_00451 7.67e-66 yczJ - - S - - - biosynthesis
NOGEOMFM_00452 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
NOGEOMFM_00453 8.6e-220 ycsN - - S - - - Oxidoreductase
NOGEOMFM_00454 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
NOGEOMFM_00455 0.0 ydaB - - IQ - - - acyl-CoA ligase
NOGEOMFM_00456 1e-127 ydaC - - Q - - - Methyltransferase domain
NOGEOMFM_00457 1.07e-206 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NOGEOMFM_00458 1.12e-124 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
NOGEOMFM_00459 6.34e-132 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NOGEOMFM_00460 3.04e-100 ydaG - - S - - - general stress protein
NOGEOMFM_00461 1.31e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NOGEOMFM_00462 1.09e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
NOGEOMFM_00463 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NOGEOMFM_00464 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NOGEOMFM_00465 1.11e-260 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
NOGEOMFM_00466 3.66e-192 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
NOGEOMFM_00467 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
NOGEOMFM_00468 1.93e-304 ydaM - - M - - - Glycosyl transferase family group 2
NOGEOMFM_00469 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
NOGEOMFM_00470 0.0 ydaO - - E - - - amino acid
NOGEOMFM_00471 2.54e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NOGEOMFM_00472 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
NOGEOMFM_00474 6.14e-53 - - - - - - - -
NOGEOMFM_00475 3.2e-285 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NOGEOMFM_00476 1.67e-42 ydaS - - S - - - membrane
NOGEOMFM_00477 2.25e-100 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
NOGEOMFM_00478 7.14e-189 ydbA - - P - - - EcsC protein family
NOGEOMFM_00479 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
NOGEOMFM_00480 7.58e-79 ydbB - - G - - - Cupin domain
NOGEOMFM_00481 4.45e-83 ydbC - - S - - - Domain of unknown function (DUF4937
NOGEOMFM_00482 1.06e-195 ydbD - - P ko:K07217 - ko00000 Catalase
NOGEOMFM_00483 1.43e-250 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NOGEOMFM_00484 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NOGEOMFM_00485 1.38e-154 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NOGEOMFM_00486 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NOGEOMFM_00487 1.32e-230 ydbI - - S - - - AI-2E family transporter
NOGEOMFM_00488 3.23e-219 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_00489 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NOGEOMFM_00490 7.67e-69 ydbL - - - - - - -
NOGEOMFM_00491 7.45e-280 ydbM - - I - - - acyl-CoA dehydrogenase
NOGEOMFM_00492 1.49e-26 - - - S - - - Fur-regulated basic protein B
NOGEOMFM_00494 1.35e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NOGEOMFM_00495 4.19e-75 ydbP - - CO - - - Thioredoxin
NOGEOMFM_00496 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NOGEOMFM_00497 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NOGEOMFM_00498 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NOGEOMFM_00499 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
NOGEOMFM_00500 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
NOGEOMFM_00501 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
NOGEOMFM_00502 1.6e-77 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NOGEOMFM_00503 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
NOGEOMFM_00504 5.29e-284 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NOGEOMFM_00505 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NOGEOMFM_00506 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NOGEOMFM_00507 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
NOGEOMFM_00508 7.34e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
NOGEOMFM_00509 8.56e-90 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NOGEOMFM_00510 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
NOGEOMFM_00511 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
NOGEOMFM_00512 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NOGEOMFM_00513 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NOGEOMFM_00514 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
NOGEOMFM_00518 1.32e-106 ydcG - - S - - - EVE domain
NOGEOMFM_00519 1.54e-101 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NOGEOMFM_00520 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
NOGEOMFM_00521 1.53e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NOGEOMFM_00529 7.32e-92 - - - J - - - Acetyltransferase (GNAT) domain
NOGEOMFM_00530 2.85e-58 - - - - - - - -
NOGEOMFM_00531 3.85e-24 - - - S ko:K21493 - ko00000,ko01000,ko02048 LXG domain of WXG superfamily
NOGEOMFM_00532 8.43e-29 - - - L ko:K07451,ko:K07452 - ko00000,ko01000,ko02048 HNH endonuclease
NOGEOMFM_00533 9.05e-56 - - - L - - - HNH nucleases
NOGEOMFM_00536 7.24e-08 - - - S - - - Putative amidase domain
NOGEOMFM_00539 1.54e-46 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
NOGEOMFM_00540 6e-53 - - - - - - - -
NOGEOMFM_00544 4.24e-146 ydeA - - S - - - DJ-1/PfpI family
NOGEOMFM_00545 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
NOGEOMFM_00546 5.92e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
NOGEOMFM_00547 3.56e-184 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NOGEOMFM_00548 2.18e-213 - - - K - - - AraC-like ligand binding domain
NOGEOMFM_00549 2.37e-222 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NOGEOMFM_00550 4.94e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
NOGEOMFM_00551 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NOGEOMFM_00552 3.8e-277 ydeG - - EGP - - - Major facilitator superfamily
NOGEOMFM_00553 9.2e-70 ydeH - - - - - - -
NOGEOMFM_00554 6.99e-136 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
NOGEOMFM_00555 2.46e-140 - - - - - - - -
NOGEOMFM_00556 2.79e-100 - - - I - - - Ribosomal RNA adenine dimethylase
NOGEOMFM_00557 5.54e-146 - - - T - - - Transcriptional regulator
NOGEOMFM_00558 2.65e-176 - - - T - - - COG0642 Signal transduction histidine kinase
NOGEOMFM_00559 4.01e-92 - - - S - - - SNARE associated Golgi protein
NOGEOMFM_00560 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
NOGEOMFM_00561 4.22e-111 - - - K - - - Transcriptional regulator C-terminal region
NOGEOMFM_00563 1.49e-193 ydeK - - EG - - - -transporter
NOGEOMFM_00564 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NOGEOMFM_00565 3.54e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
NOGEOMFM_00566 2.31e-133 - - - S ko:K07002 - ko00000 Serine hydrolase
NOGEOMFM_00567 8.68e-74 - - - K - - - HxlR-like helix-turn-helix
NOGEOMFM_00568 1.32e-193 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NOGEOMFM_00569 2.92e-90 ydeP - - K - - - Transcriptional regulator
NOGEOMFM_00570 2.36e-143 ywrO - - S ko:K11748 - ko00000,ko02000 NADPH-quinone reductase (modulator of drug activity B)
NOGEOMFM_00571 1.13e-256 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
NOGEOMFM_00572 4.73e-133 ydeS - - K - - - Transcriptional regulator
NOGEOMFM_00573 1.05e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
NOGEOMFM_00574 3.53e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NOGEOMFM_00575 2.59e-187 - - - J - - - GNAT acetyltransferase
NOGEOMFM_00576 9.56e-195 - - - EG - - - EamA-like transporter family
NOGEOMFM_00577 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NOGEOMFM_00578 2.34e-148 ydfE - - S - - - Flavin reductase like domain
NOGEOMFM_00579 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
NOGEOMFM_00580 1.12e-103 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NOGEOMFM_00582 7.24e-247 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NOGEOMFM_00583 2.3e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NOGEOMFM_00584 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
NOGEOMFM_00585 5.32e-186 - - - S - - - Alpha/beta hydrolase family
NOGEOMFM_00586 3.87e-13 - - - S - - - Alpha/beta hydrolase family
NOGEOMFM_00587 3.77e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
NOGEOMFM_00588 1.18e-186 - - - K - - - Bacterial transcription activator, effector binding domain
NOGEOMFM_00589 5.22e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NOGEOMFM_00590 2.83e-144 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
NOGEOMFM_00591 1.51e-235 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NOGEOMFM_00592 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
NOGEOMFM_00593 7.63e-74 ydfQ - - CO - - - Thioredoxin
NOGEOMFM_00594 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
NOGEOMFM_00595 5.33e-39 - - - - - - - -
NOGEOMFM_00597 6.08e-153 ydfR - - S - - - Protein of unknown function (DUF421)
NOGEOMFM_00598 2.57e-159 ydfS - - S - - - Protein of unknown function (DUF421)
NOGEOMFM_00599 3.13e-99 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NOGEOMFM_00600 2.74e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
NOGEOMFM_00601 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
NOGEOMFM_00602 4.04e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
NOGEOMFM_00603 1.93e-68 - - - S - - - DoxX-like family
NOGEOMFM_00604 2.46e-68 yycN - - K - - - Acetyltransferase
NOGEOMFM_00605 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
NOGEOMFM_00606 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NOGEOMFM_00607 2.32e-115 - - - S - - - DinB family
NOGEOMFM_00608 8.04e-102 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NOGEOMFM_00609 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
NOGEOMFM_00610 9.12e-147 ydgI - - C - - - nitroreductase
NOGEOMFM_00611 6.63e-90 - - - K - - - Winged helix DNA-binding domain
NOGEOMFM_00612 4.02e-265 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
NOGEOMFM_00613 1.02e-154 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
NOGEOMFM_00614 4.31e-157 ydhC - - K - - - FCD
NOGEOMFM_00615 7.33e-309 ydhD - - M - - - Glycosyl hydrolase
NOGEOMFM_00616 7.9e-289 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NOGEOMFM_00617 4.79e-160 - - - - - - - -
NOGEOMFM_00618 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
NOGEOMFM_00619 2.74e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
NOGEOMFM_00621 2.2e-107 - - - K - - - Acetyltransferase (GNAT) domain
NOGEOMFM_00622 9.03e-230 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NOGEOMFM_00623 7.76e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
NOGEOMFM_00624 8.95e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
NOGEOMFM_00625 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NOGEOMFM_00626 3.39e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NOGEOMFM_00627 6.51e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NOGEOMFM_00628 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NOGEOMFM_00629 1.83e-169 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
NOGEOMFM_00630 4.94e-214 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
NOGEOMFM_00631 8.45e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NOGEOMFM_00632 6.49e-269 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
NOGEOMFM_00633 4.89e-202 ydhU - - P ko:K07217 - ko00000 Catalase
NOGEOMFM_00636 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NOGEOMFM_00639 1.9e-231 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NOGEOMFM_00640 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
NOGEOMFM_00641 1.76e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
NOGEOMFM_00642 2.34e-107 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NOGEOMFM_00643 5.46e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NOGEOMFM_00644 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
NOGEOMFM_00645 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NOGEOMFM_00646 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NOGEOMFM_00647 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NOGEOMFM_00648 8.73e-162 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NOGEOMFM_00649 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
NOGEOMFM_00650 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
NOGEOMFM_00651 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NOGEOMFM_00652 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NOGEOMFM_00654 1.93e-53 - - - - - - - -
NOGEOMFM_00655 7.05e-293 - - - S - - - Bacterial EndoU nuclease
NOGEOMFM_00658 4.31e-82 yozB - - S ko:K08976 - ko00000 Membrane
NOGEOMFM_00659 8.95e-31 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
NOGEOMFM_00660 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
NOGEOMFM_00661 4.32e-258 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
NOGEOMFM_00662 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
NOGEOMFM_00663 7.03e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
NOGEOMFM_00664 1.08e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
NOGEOMFM_00665 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NOGEOMFM_00666 3.96e-177 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
NOGEOMFM_00667 1.79e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
NOGEOMFM_00668 1.37e-248 - - - S - - - Ion transport 2 domain protein
NOGEOMFM_00669 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NOGEOMFM_00670 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
NOGEOMFM_00671 1.79e-84 ydjM - - M - - - Lytic transglycolase
NOGEOMFM_00672 1.27e-204 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
NOGEOMFM_00674 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
NOGEOMFM_00675 3.21e-205 - - - I - - - Alpha/beta hydrolase family
NOGEOMFM_00676 1.9e-233 yeaA - - S - - - Protein of unknown function (DUF4003)
NOGEOMFM_00677 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
NOGEOMFM_00678 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NOGEOMFM_00679 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NOGEOMFM_00680 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
NOGEOMFM_00681 1.59e-285 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NOGEOMFM_00682 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
NOGEOMFM_00683 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NOGEOMFM_00684 2.81e-282 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NOGEOMFM_00685 2.78e-163 yebC - - M - - - Membrane
NOGEOMFM_00687 2.66e-120 yebE - - S - - - UPF0316 protein
NOGEOMFM_00688 3.13e-38 yebG - - S - - - NETI protein
NOGEOMFM_00689 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NOGEOMFM_00690 4.83e-274 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NOGEOMFM_00691 1.98e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NOGEOMFM_00692 7.13e-169 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NOGEOMFM_00693 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NOGEOMFM_00694 6.66e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NOGEOMFM_00695 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NOGEOMFM_00696 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NOGEOMFM_00697 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NOGEOMFM_00698 8.88e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NOGEOMFM_00699 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NOGEOMFM_00700 5.69e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NOGEOMFM_00701 1.29e-94 - - - K - - - helix_turn_helix ASNC type
NOGEOMFM_00702 4.8e-291 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
NOGEOMFM_00703 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
NOGEOMFM_00704 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
NOGEOMFM_00705 9.18e-242 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
NOGEOMFM_00706 7.62e-68 yerC - - S - - - protein conserved in bacteria
NOGEOMFM_00707 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
NOGEOMFM_00709 7.43e-160 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NOGEOMFM_00710 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NOGEOMFM_00711 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NOGEOMFM_00712 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
NOGEOMFM_00713 2.45e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
NOGEOMFM_00714 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
NOGEOMFM_00715 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NOGEOMFM_00716 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NOGEOMFM_00717 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NOGEOMFM_00718 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NOGEOMFM_00719 2.08e-190 yerO - - K - - - Transcriptional regulator
NOGEOMFM_00720 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NOGEOMFM_00721 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NOGEOMFM_00722 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NOGEOMFM_00723 0.0 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system methyltransferase subunit()
NOGEOMFM_00724 6.7e-95 - - - V - - - Type I restriction modification DNA specificity domain
NOGEOMFM_00727 3.95e-125 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NOGEOMFM_00729 4.5e-41 - - - S - - - Colicin immunity protein / pyocin immunity protein
NOGEOMFM_00731 8.48e-105 - - - S - - - Protein of unknown function, DUF600
NOGEOMFM_00732 1.09e-73 - - - S - - - Protein of unknown function, DUF600
NOGEOMFM_00733 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
NOGEOMFM_00734 2.32e-235 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
NOGEOMFM_00735 1.42e-270 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
NOGEOMFM_00737 1.09e-162 yeeN - - K - - - transcriptional regulatory protein
NOGEOMFM_00739 2.85e-129 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_00740 2.02e-106 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
NOGEOMFM_00741 1.23e-195 yesF - - GM - - - NAD(P)H-binding
NOGEOMFM_00742 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
NOGEOMFM_00743 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
NOGEOMFM_00744 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
NOGEOMFM_00745 2.4e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
NOGEOMFM_00746 1.95e-132 yesL - - S - - - Protein of unknown function, DUF624
NOGEOMFM_00747 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NOGEOMFM_00748 1.89e-255 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
NOGEOMFM_00749 6.85e-313 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
NOGEOMFM_00750 2.02e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NOGEOMFM_00751 5.11e-210 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NOGEOMFM_00752 5.63e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
NOGEOMFM_00753 0.0 yesS - - K - - - Transcriptional regulator
NOGEOMFM_00754 9.8e-169 - - - E - - - GDSL-like Lipase/Acylhydrolase
NOGEOMFM_00755 7.22e-163 yesU - - S - - - Domain of unknown function (DUF1961)
NOGEOMFM_00756 7.78e-143 - - - S - - - Protein of unknown function, DUF624
NOGEOMFM_00757 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
NOGEOMFM_00758 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
NOGEOMFM_00759 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
NOGEOMFM_00760 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
NOGEOMFM_00761 0.0 yetA - - - - - - -
NOGEOMFM_00762 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NOGEOMFM_00763 6.84e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
NOGEOMFM_00764 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NOGEOMFM_00765 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
NOGEOMFM_00766 1.49e-156 yetF - - S - - - membrane
NOGEOMFM_00767 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
NOGEOMFM_00768 7.08e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NOGEOMFM_00769 9.79e-45 - - - - - - - -
NOGEOMFM_00770 3.08e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NOGEOMFM_00771 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
NOGEOMFM_00772 2.45e-133 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
NOGEOMFM_00773 2.75e-116 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
NOGEOMFM_00774 1.78e-265 yetM - - CH - - - FAD binding domain
NOGEOMFM_00775 2.57e-171 - - - M - - - Membrane
NOGEOMFM_00776 4.11e-251 yetN - - S - - - Protein of unknown function (DUF3900)
NOGEOMFM_00777 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NOGEOMFM_00778 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NOGEOMFM_00779 2.41e-187 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
NOGEOMFM_00780 1.37e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
NOGEOMFM_00781 3.99e-231 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
NOGEOMFM_00782 2.44e-286 yfnE - - S - - - Glycosyltransferase like family 2
NOGEOMFM_00783 2.84e-244 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
NOGEOMFM_00784 6.21e-268 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NOGEOMFM_00785 9.43e-171 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NOGEOMFM_00786 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
NOGEOMFM_00787 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NOGEOMFM_00788 5.14e-161 yfmS - - NT - - - chemotaxis protein
NOGEOMFM_00789 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NOGEOMFM_00790 6.48e-99 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
NOGEOMFM_00791 3.03e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
NOGEOMFM_00792 7.24e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
NOGEOMFM_00793 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NOGEOMFM_00794 1.2e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
NOGEOMFM_00795 2.55e-105 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
NOGEOMFM_00796 6.98e-241 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
NOGEOMFM_00797 1.72e-268 - - - G - - - Major Facilitator Superfamily
NOGEOMFM_00798 0.0 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
NOGEOMFM_00799 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
NOGEOMFM_00800 4.94e-222 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NOGEOMFM_00801 8.17e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NOGEOMFM_00802 2.76e-219 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NOGEOMFM_00803 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
NOGEOMFM_00804 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
NOGEOMFM_00805 4.06e-306 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
NOGEOMFM_00806 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NOGEOMFM_00807 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NOGEOMFM_00808 3.96e-154 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NOGEOMFM_00809 1.45e-232 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
NOGEOMFM_00810 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NOGEOMFM_00811 2.94e-193 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NOGEOMFM_00812 1.37e-275 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NOGEOMFM_00813 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NOGEOMFM_00814 5.91e-158 yflK - - S - - - protein conserved in bacteria
NOGEOMFM_00815 1.1e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
NOGEOMFM_00816 9.81e-27 yflI - - - - - - -
NOGEOMFM_00817 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
NOGEOMFM_00818 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
NOGEOMFM_00819 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NOGEOMFM_00820 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NOGEOMFM_00821 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
NOGEOMFM_00822 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
NOGEOMFM_00823 2.19e-249 yfkT - - E ko:K06309 - ko00000 Spore germination protein
NOGEOMFM_00825 9.28e-271 yfkR - - S ko:K06297,ko:K06308 - ko00000 spore germination
NOGEOMFM_00826 0.0 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
NOGEOMFM_00827 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NOGEOMFM_00828 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
NOGEOMFM_00829 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
NOGEOMFM_00830 5.27e-161 frp - - C - - - nitroreductase
NOGEOMFM_00831 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NOGEOMFM_00832 8.44e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NOGEOMFM_00833 6.21e-266 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NOGEOMFM_00834 7.27e-42 yfkK - - S - - - Belongs to the UPF0435 family
NOGEOMFM_00835 2.14e-110 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NOGEOMFM_00836 2.53e-67 yfkI - - S - - - gas vesicle protein
NOGEOMFM_00837 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NOGEOMFM_00838 1.64e-12 - - - - - - - -
NOGEOMFM_00839 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NOGEOMFM_00840 1.9e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
NOGEOMFM_00841 3.69e-189 yfkD - - S - - - YfkD-like protein
NOGEOMFM_00842 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
NOGEOMFM_00843 7.17e-283 yfkA - - S - - - YfkB-like domain
NOGEOMFM_00844 3.26e-36 yfjT - - - - - - -
NOGEOMFM_00845 4.19e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
NOGEOMFM_00846 5.16e-189 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NOGEOMFM_00847 7.8e-237 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
NOGEOMFM_00848 2.76e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NOGEOMFM_00849 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NOGEOMFM_00850 3.04e-59 - - - S - - - YfzA-like protein
NOGEOMFM_00851 3.47e-243 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NOGEOMFM_00852 9.55e-111 yfjM - - S - - - Psort location Cytoplasmic, score
NOGEOMFM_00853 9.2e-243 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NOGEOMFM_00854 2.64e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NOGEOMFM_00855 2.7e-261 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NOGEOMFM_00856 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NOGEOMFM_00857 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
NOGEOMFM_00858 2.75e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
NOGEOMFM_00859 7.42e-75 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
NOGEOMFM_00860 1.9e-109 - - - S - - - Family of unknown function (DUF5381)
NOGEOMFM_00861 3.83e-161 yfjC - - - - - - -
NOGEOMFM_00862 6.91e-241 yfjB - - - - - - -
NOGEOMFM_00863 1.6e-60 yfjA - - S - - - Belongs to the WXG100 family
NOGEOMFM_00864 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NOGEOMFM_00865 2.05e-179 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
NOGEOMFM_00866 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NOGEOMFM_00867 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
NOGEOMFM_00868 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
NOGEOMFM_00869 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NOGEOMFM_00870 3.34e-83 yfiD3 - - S - - - DoxX
NOGEOMFM_00871 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
NOGEOMFM_00873 1.98e-271 baeS - - T - - - Histidine kinase
NOGEOMFM_00874 6.07e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
NOGEOMFM_00875 7.89e-217 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_00876 1.46e-264 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
NOGEOMFM_00877 3.84e-259 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NOGEOMFM_00878 1.89e-128 padR - - K - - - transcriptional
NOGEOMFM_00879 3.2e-127 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
NOGEOMFM_00880 8.95e-251 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NOGEOMFM_00881 9.81e-129 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
NOGEOMFM_00882 0.0 yfiU - - EGP - - - the major facilitator superfamily
NOGEOMFM_00883 2.11e-103 yfiV - - K - - - transcriptional
NOGEOMFM_00884 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NOGEOMFM_00885 1.56e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NOGEOMFM_00886 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NOGEOMFM_00887 7.36e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NOGEOMFM_00888 7.61e-215 yfhB - - S - - - PhzF family
NOGEOMFM_00889 2.87e-138 yfhC - - C - - - nitroreductase
NOGEOMFM_00890 8.86e-35 yfhD - - S - - - YfhD-like protein
NOGEOMFM_00891 3.11e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
NOGEOMFM_00892 9.32e-181 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
NOGEOMFM_00893 4.8e-67 yfhH - - S - - - Protein of unknown function (DUF1811)
NOGEOMFM_00894 3.47e-268 yfhI - - EGP - - - -transporter
NOGEOMFM_00895 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
NOGEOMFM_00896 8.95e-60 yfhJ - - S - - - WVELL protein
NOGEOMFM_00897 1.7e-117 yfhK - - T - - - Bacterial SH3 domain homologues
NOGEOMFM_00898 4.74e-62 yfhL - - S - - - SdpI/YhfL protein family
NOGEOMFM_00899 3.93e-218 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
NOGEOMFM_00900 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NOGEOMFM_00901 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NOGEOMFM_00902 7.22e-237 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
NOGEOMFM_00903 1.2e-267 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
NOGEOMFM_00904 1.73e-48 yfhS - - - - - - -
NOGEOMFM_00905 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NOGEOMFM_00906 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
NOGEOMFM_00907 1.88e-63 ygaB - - S - - - YgaB-like protein
NOGEOMFM_00908 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
NOGEOMFM_00909 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
NOGEOMFM_00910 1.87e-238 ygaE - - S - - - Membrane
NOGEOMFM_00911 1.33e-311 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NOGEOMFM_00912 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
NOGEOMFM_00913 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NOGEOMFM_00914 3.95e-72 ygzB - - S - - - UPF0295 protein
NOGEOMFM_00915 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
NOGEOMFM_00916 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NOGEOMFM_00933 8.59e-98 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
NOGEOMFM_00934 1.58e-36 - - - - - - - -
NOGEOMFM_00935 3.18e-169 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
NOGEOMFM_00936 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NOGEOMFM_00937 0.0 ygaK - - C - - - Berberine and berberine like
NOGEOMFM_00939 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NOGEOMFM_00940 9.01e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NOGEOMFM_00941 8.45e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
NOGEOMFM_00942 4.82e-189 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NOGEOMFM_00943 2.2e-274 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
NOGEOMFM_00945 4.82e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NOGEOMFM_00946 2.79e-102 ygaO - - - - - - -
NOGEOMFM_00947 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_00949 1.92e-147 yhzB - - S - - - B3/4 domain
NOGEOMFM_00950 4.88e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NOGEOMFM_00951 1.32e-223 yhbB - - S - - - Putative amidase domain
NOGEOMFM_00952 5.37e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NOGEOMFM_00953 1.38e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
NOGEOMFM_00954 2.66e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NOGEOMFM_00955 4.06e-103 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
NOGEOMFM_00956 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
NOGEOMFM_00957 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
NOGEOMFM_00958 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
NOGEOMFM_00959 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
NOGEOMFM_00960 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
NOGEOMFM_00961 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
NOGEOMFM_00962 3.95e-59 yhcC - - - - - - -
NOGEOMFM_00963 2.92e-69 - - - - - - - -
NOGEOMFM_00964 4.78e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_00965 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_00966 4.37e-211 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_00967 1.4e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NOGEOMFM_00968 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
NOGEOMFM_00969 1.34e-195 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NOGEOMFM_00970 7.08e-251 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
NOGEOMFM_00971 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NOGEOMFM_00972 1.13e-70 yhcM - - - - - - -
NOGEOMFM_00973 1.74e-107 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NOGEOMFM_00974 3.64e-223 yhcP - - - - - - -
NOGEOMFM_00975 1.68e-146 yhcQ - - M - - - Spore coat protein
NOGEOMFM_00976 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NOGEOMFM_00977 7.24e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
NOGEOMFM_00978 4.78e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NOGEOMFM_00979 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
NOGEOMFM_00980 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
NOGEOMFM_00981 4.32e-155 yhcW - - S ko:K07025 - ko00000 hydrolase
NOGEOMFM_00982 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NOGEOMFM_00983 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NOGEOMFM_00984 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NOGEOMFM_00985 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NOGEOMFM_00986 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NOGEOMFM_00987 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NOGEOMFM_00988 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
NOGEOMFM_00989 7.33e-270 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
NOGEOMFM_00990 7.42e-142 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NOGEOMFM_00991 5.68e-117 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
NOGEOMFM_00992 1.65e-51 yhdB - - S - - - YhdB-like protein
NOGEOMFM_00993 1.25e-72 yhdC - - S - - - Protein of unknown function (DUF3889)
NOGEOMFM_00994 1.2e-268 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NOGEOMFM_00995 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
NOGEOMFM_00996 1.51e-306 ygxB - - M - - - Conserved TM helix
NOGEOMFM_00997 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
NOGEOMFM_00998 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
NOGEOMFM_00999 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NOGEOMFM_01000 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_01001 1.45e-258 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NOGEOMFM_01002 1.58e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NOGEOMFM_01003 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
NOGEOMFM_01004 2.48e-309 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NOGEOMFM_01005 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NOGEOMFM_01006 2.05e-99 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NOGEOMFM_01007 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
NOGEOMFM_01008 3.54e-257 yhdL - - S - - - Sigma factor regulator N-terminal
NOGEOMFM_01009 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NOGEOMFM_01010 1.93e-243 yhdN - - C - - - Aldo keto reductase
NOGEOMFM_01011 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NOGEOMFM_01012 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NOGEOMFM_01013 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
NOGEOMFM_01014 2.08e-283 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NOGEOMFM_01015 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
NOGEOMFM_01016 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NOGEOMFM_01017 5.83e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NOGEOMFM_01018 5.44e-174 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NOGEOMFM_01019 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
NOGEOMFM_01020 4.51e-260 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
NOGEOMFM_01021 2.93e-180 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NOGEOMFM_01022 5.7e-200 nodB1 - - G - - - deacetylase
NOGEOMFM_01023 3.16e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NOGEOMFM_01024 3.77e-305 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NOGEOMFM_01025 3.85e-109 nhaX - - T - - - Belongs to the universal stress protein A family
NOGEOMFM_01026 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NOGEOMFM_01027 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NOGEOMFM_01028 3.31e-143 yheG - - GM - - - NAD(P)H-binding
NOGEOMFM_01029 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
NOGEOMFM_01030 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
NOGEOMFM_01031 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
NOGEOMFM_01032 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
NOGEOMFM_01033 1.69e-258 yheB - - S - - - Belongs to the UPF0754 family
NOGEOMFM_01034 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
NOGEOMFM_01035 2.24e-262 yhaZ - - L - - - DNA alkylation repair enzyme
NOGEOMFM_01036 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
NOGEOMFM_01037 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
NOGEOMFM_01038 7.54e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
NOGEOMFM_01039 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NOGEOMFM_01041 1.6e-172 yhaR - - I - - - enoyl-CoA hydratase
NOGEOMFM_01042 2.29e-36 - - - S - - - YhzD-like protein
NOGEOMFM_01043 1.31e-213 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_01044 5.99e-271 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
NOGEOMFM_01045 2.22e-299 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
NOGEOMFM_01046 0.0 yhaN - - L - - - AAA domain
NOGEOMFM_01047 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
NOGEOMFM_01048 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
NOGEOMFM_01049 2.29e-179 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NOGEOMFM_01050 1.4e-116 yhaK - - S - - - Putative zincin peptidase
NOGEOMFM_01051 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
NOGEOMFM_01052 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
NOGEOMFM_01053 1.74e-54 yhaH - - S - - - YtxH-like protein
NOGEOMFM_01054 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
NOGEOMFM_01055 2.51e-260 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NOGEOMFM_01056 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NOGEOMFM_01057 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
NOGEOMFM_01058 1.27e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NOGEOMFM_01059 1.01e-161 ecsC - - S - - - EcsC protein family
NOGEOMFM_01060 1.48e-289 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NOGEOMFM_01061 2.31e-313 yhfA - - C - - - membrane
NOGEOMFM_01062 1.23e-45 - - - C - - - Rubrerythrin
NOGEOMFM_01063 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NOGEOMFM_01064 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NOGEOMFM_01065 1.76e-257 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NOGEOMFM_01066 5.66e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NOGEOMFM_01067 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NOGEOMFM_01068 1e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_01069 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
NOGEOMFM_01070 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NOGEOMFM_01071 1.61e-178 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
NOGEOMFM_01072 2.68e-253 yhfE - - G - - - peptidase M42
NOGEOMFM_01073 6.22e-93 - - - S - - - ASCH
NOGEOMFM_01074 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NOGEOMFM_01075 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NOGEOMFM_01076 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NOGEOMFM_01077 1.01e-141 yhfK - - GM - - - NmrA-like family
NOGEOMFM_01078 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NOGEOMFM_01079 5.6e-85 yhfM - - - - - - -
NOGEOMFM_01080 1.37e-307 yhfN - - O - - - Peptidase M48
NOGEOMFM_01081 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NOGEOMFM_01082 1.47e-100 - - - K - - - acetyltransferase
NOGEOMFM_01083 8.03e-231 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
NOGEOMFM_01084 2.77e-223 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NOGEOMFM_01085 3.93e-140 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
NOGEOMFM_01086 1.48e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NOGEOMFM_01087 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
NOGEOMFM_01088 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NOGEOMFM_01089 2.62e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
NOGEOMFM_01090 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
NOGEOMFM_01091 7.82e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NOGEOMFM_01092 9.84e-45 yhzC - - S - - - IDEAL
NOGEOMFM_01093 6.29e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
NOGEOMFM_01094 2.1e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NOGEOMFM_01095 2.04e-56 yhjA - - S - - - Excalibur calcium-binding domain
NOGEOMFM_01096 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NOGEOMFM_01097 9.31e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
NOGEOMFM_01098 2.12e-77 yhjD - - - - - - -
NOGEOMFM_01099 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
NOGEOMFM_01100 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NOGEOMFM_01101 0.0 yhjG - - CH - - - FAD binding domain
NOGEOMFM_01102 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
NOGEOMFM_01103 3.12e-273 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
NOGEOMFM_01104 3.98e-257 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
NOGEOMFM_01105 2.63e-205 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
NOGEOMFM_01106 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
NOGEOMFM_01107 1.07e-239 yhjM - - K - - - Transcriptional regulator
NOGEOMFM_01108 1.02e-258 yhjN - - S ko:K07120 - ko00000 membrane
NOGEOMFM_01109 4.25e-271 - - - EGP - - - Transmembrane secretion effector
NOGEOMFM_01110 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
NOGEOMFM_01111 2.06e-67 yhjQ - - C - - - COG1145 Ferredoxin
NOGEOMFM_01112 2.19e-100 yhjR - - S - - - Rubrerythrin
NOGEOMFM_01113 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
NOGEOMFM_01114 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NOGEOMFM_01115 1.63e-279 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NOGEOMFM_01116 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
NOGEOMFM_01117 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
NOGEOMFM_01118 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
NOGEOMFM_01119 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
NOGEOMFM_01120 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
NOGEOMFM_01121 1e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
NOGEOMFM_01122 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
NOGEOMFM_01123 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
NOGEOMFM_01124 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
NOGEOMFM_01125 8.94e-221 cotH - - M ko:K06330 - ko00000 Spore Coat
NOGEOMFM_01126 7.64e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NOGEOMFM_01127 1.02e-74 yisL - - S - - - UPF0344 protein
NOGEOMFM_01128 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NOGEOMFM_01129 7.42e-132 yisN - - S - - - Protein of unknown function (DUF2777)
NOGEOMFM_01130 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NOGEOMFM_01131 1.07e-114 yizA - - S - - - Damage-inducible protein DinB
NOGEOMFM_01132 1.54e-189 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
NOGEOMFM_01133 1.01e-310 yisQ - - V - - - Mate efflux family protein
NOGEOMFM_01134 4.04e-207 yisR - - K - - - Transcriptional regulator
NOGEOMFM_01135 1.83e-235 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
NOGEOMFM_01136 5.17e-249 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
NOGEOMFM_01137 9.94e-120 yisT - - S - - - DinB family
NOGEOMFM_01138 5.96e-128 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
NOGEOMFM_01139 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NOGEOMFM_01140 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
NOGEOMFM_01141 2.25e-199 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NOGEOMFM_01142 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NOGEOMFM_01143 1.6e-294 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
NOGEOMFM_01144 2.15e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
NOGEOMFM_01145 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
NOGEOMFM_01146 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
NOGEOMFM_01147 6.77e-145 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NOGEOMFM_01148 2.14e-283 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NOGEOMFM_01149 1.01e-291 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NOGEOMFM_01150 1.4e-200 yitH - - K - - - Acetyltransferase (GNAT) domain
NOGEOMFM_01151 5.09e-92 - - - S - - - Acetyltransferase (GNAT) domain
NOGEOMFM_01152 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NOGEOMFM_01153 1.06e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
NOGEOMFM_01154 1.94e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
NOGEOMFM_01155 4.16e-122 - - - - - - - -
NOGEOMFM_01156 1.42e-218 - - - - - - - -
NOGEOMFM_01157 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
NOGEOMFM_01158 1.2e-76 - - - K - - - Transcriptional regulator PadR-like family
NOGEOMFM_01159 6.11e-120 - - - - - - - -
NOGEOMFM_01160 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
NOGEOMFM_01161 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
NOGEOMFM_01162 9.13e-202 yitS - - S - - - protein conserved in bacteria
NOGEOMFM_01163 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NOGEOMFM_01164 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
NOGEOMFM_01165 4.11e-25 - - - S - - - Protein of unknown function (DUF3813)
NOGEOMFM_01166 1.92e-08 - - - - - - - -
NOGEOMFM_01167 3.19e-200 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NOGEOMFM_01168 5.05e-185 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NOGEOMFM_01169 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
NOGEOMFM_01170 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
NOGEOMFM_01171 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
NOGEOMFM_01172 2.04e-91 yitZ - - G - - - Major Facilitator Superfamily
NOGEOMFM_01173 7.41e-255 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NOGEOMFM_01174 7.4e-295 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NOGEOMFM_01175 5.4e-177 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
NOGEOMFM_01176 3.98e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
NOGEOMFM_01177 1.4e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NOGEOMFM_01178 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
NOGEOMFM_01179 3.66e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NOGEOMFM_01180 2.51e-39 yjzC - - S - - - YjzC-like protein
NOGEOMFM_01181 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
NOGEOMFM_01182 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
NOGEOMFM_01183 5.41e-134 yjaV - - - - - - -
NOGEOMFM_01184 6.4e-235 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
NOGEOMFM_01185 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
NOGEOMFM_01186 2.67e-38 yjzB - - - - - - -
NOGEOMFM_01187 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NOGEOMFM_01188 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NOGEOMFM_01189 9.48e-193 yjaZ - - O - - - Zn-dependent protease
NOGEOMFM_01190 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NOGEOMFM_01191 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NOGEOMFM_01192 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
NOGEOMFM_01193 3.73e-213 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NOGEOMFM_01194 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NOGEOMFM_01195 7.51e-189 yjbA - - S - - - Belongs to the UPF0736 family
NOGEOMFM_01196 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
NOGEOMFM_01197 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NOGEOMFM_01198 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NOGEOMFM_01199 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NOGEOMFM_01200 3.92e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NOGEOMFM_01201 3.12e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NOGEOMFM_01202 9.6e-260 yjbB - - EGP - - - Major Facilitator Superfamily
NOGEOMFM_01203 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NOGEOMFM_01204 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NOGEOMFM_01205 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
NOGEOMFM_01206 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NOGEOMFM_01207 4.38e-282 coiA - - S ko:K06198 - ko00000 Competence protein
NOGEOMFM_01208 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
NOGEOMFM_01209 2.68e-28 - - - - - - - -
NOGEOMFM_01211 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NOGEOMFM_01212 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
NOGEOMFM_01213 7.22e-129 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NOGEOMFM_01214 4.94e-128 yjbK - - S - - - protein conserved in bacteria
NOGEOMFM_01215 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
NOGEOMFM_01216 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
NOGEOMFM_01217 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NOGEOMFM_01218 9.01e-204 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NOGEOMFM_01219 6.5e-162 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NOGEOMFM_01220 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NOGEOMFM_01221 1.11e-174 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NOGEOMFM_01222 2.32e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
NOGEOMFM_01223 1.42e-271 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
NOGEOMFM_01224 1.8e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
NOGEOMFM_01225 2.76e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NOGEOMFM_01226 6.18e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NOGEOMFM_01227 3.98e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NOGEOMFM_01228 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NOGEOMFM_01229 3.11e-98 yjbX - - S - - - Spore coat protein
NOGEOMFM_01230 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
NOGEOMFM_01231 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
NOGEOMFM_01232 1.23e-95 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
NOGEOMFM_01233 9.3e-32 cotW - - - ko:K06341 - ko00000 -
NOGEOMFM_01234 2.34e-66 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
NOGEOMFM_01235 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
NOGEOMFM_01238 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
NOGEOMFM_01239 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NOGEOMFM_01240 6.31e-51 - - - - - - - -
NOGEOMFM_01241 1.1e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NOGEOMFM_01242 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
NOGEOMFM_01243 1.91e-177 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
NOGEOMFM_01244 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NOGEOMFM_01245 7.47e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NOGEOMFM_01246 7.14e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
NOGEOMFM_01247 1.05e-273 yjcL - - S - - - Protein of unknown function (DUF819)
NOGEOMFM_01250 1.33e-50 - - - - - - - -
NOGEOMFM_01252 2.35e-295 - - - M - - - nucleic acid phosphodiester bond hydrolysis
NOGEOMFM_01255 1.42e-09 - - - S - - - YolD-like protein
NOGEOMFM_01256 1.92e-47 - - - - - - - -
NOGEOMFM_01257 3.94e-26 - - - - - - - -
NOGEOMFM_01258 2.49e-07 - - - - - - - -
NOGEOMFM_01259 5.19e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
NOGEOMFM_01260 9.79e-181 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
NOGEOMFM_01261 0.000759 - - - - - - - -
NOGEOMFM_01262 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
NOGEOMFM_01263 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NOGEOMFM_01264 1.4e-237 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NOGEOMFM_01265 3.08e-74 yjdF3 - - S - - - Protein of unknown function (DUF2992)
NOGEOMFM_01266 5.12e-117 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NOGEOMFM_01268 8.3e-105 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NOGEOMFM_01269 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
NOGEOMFM_01270 4.66e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
NOGEOMFM_01271 1.52e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NOGEOMFM_01273 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
NOGEOMFM_01274 2.22e-108 - - - S - - - Protein of unknown function (DUF2690)
NOGEOMFM_01275 1.95e-30 yjfB - - S - - - Putative motility protein
NOGEOMFM_01276 1.42e-213 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
NOGEOMFM_01277 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
NOGEOMFM_01278 1.22e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
NOGEOMFM_01279 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
NOGEOMFM_01280 6.51e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
NOGEOMFM_01282 3.17e-148 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NOGEOMFM_01284 1.25e-281 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NOGEOMFM_01285 5.89e-278 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NOGEOMFM_01286 1.11e-41 - - - - - - - -
NOGEOMFM_01287 1.13e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NOGEOMFM_01288 1.82e-155 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
NOGEOMFM_01289 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NOGEOMFM_01290 3.12e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
NOGEOMFM_01291 1.42e-117 yjlB - - S - - - Cupin domain
NOGEOMFM_01292 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
NOGEOMFM_01293 3.56e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NOGEOMFM_01294 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
NOGEOMFM_01295 4.34e-314 - - - G ko:K03292 - ko00000 symporter YjmB
NOGEOMFM_01296 2.08e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
NOGEOMFM_01297 9.24e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
NOGEOMFM_01298 3.92e-273 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
NOGEOMFM_01299 5.47e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NOGEOMFM_01300 9.24e-288 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
NOGEOMFM_01301 9.87e-238 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
NOGEOMFM_01302 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
NOGEOMFM_01303 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
NOGEOMFM_01304 1.59e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
NOGEOMFM_01305 2.71e-103 yjoA - - S - - - DinB family
NOGEOMFM_01306 1.67e-311 VCP - - O - - - AAA domain (dynein-related subfamily)
NOGEOMFM_01307 3.5e-271 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NOGEOMFM_01309 1.79e-55 - - - S - - - YCII-related domain
NOGEOMFM_01310 5.12e-216 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NOGEOMFM_01311 1.35e-80 yjqA - - S - - - Bacterial PH domain
NOGEOMFM_01312 3.73e-137 yjqB - - S - - - Pfam:DUF867
NOGEOMFM_01313 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
NOGEOMFM_01314 1.79e-143 xkdA - - E - - - IrrE N-terminal-like domain
NOGEOMFM_01315 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
NOGEOMFM_01317 3.73e-203 xkdB - - K - - - sequence-specific DNA binding
NOGEOMFM_01318 3.55e-151 xkdC - - L - - - Bacterial dnaA protein
NOGEOMFM_01322 9.88e-111 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NOGEOMFM_01323 7.93e-178 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
NOGEOMFM_01324 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
NOGEOMFM_01325 0.0 yqbA - - S - - - portal protein
NOGEOMFM_01326 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
NOGEOMFM_01327 3.91e-217 xkdG - - S - - - Phage capsid family
NOGEOMFM_01328 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
NOGEOMFM_01329 1.5e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
NOGEOMFM_01330 8.3e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
NOGEOMFM_01331 2.87e-101 xkdJ - - - - - - -
NOGEOMFM_01332 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
NOGEOMFM_01333 6.01e-99 xkdM - - S - - - Phage tail tube protein
NOGEOMFM_01334 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
NOGEOMFM_01335 0.0 xkdO - - L - - - Transglycosylase SLT domain
NOGEOMFM_01336 4.25e-152 xkdP - - S - - - Lysin motif
NOGEOMFM_01337 1.56e-230 xkdQ - - G - - - NLP P60 protein
NOGEOMFM_01338 5.05e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
NOGEOMFM_01339 1.1e-89 xkdS - - S - - - Protein of unknown function (DUF2634)
NOGEOMFM_01340 1.47e-242 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NOGEOMFM_01341 3.23e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
NOGEOMFM_01342 4.43e-56 - - - - - - - -
NOGEOMFM_01343 1.87e-219 - - - - - - - -
NOGEOMFM_01344 1.28e-59 xkdW - - S - - - XkdW protein
NOGEOMFM_01345 6.35e-31 xkdX - - - - - - -
NOGEOMFM_01346 2.21e-193 xepA - - - - - - -
NOGEOMFM_01347 2.21e-51 xhlA - - S - - - Haemolysin XhlA
NOGEOMFM_01348 1.15e-52 xhlB - - S - - - SPP1 phage holin
NOGEOMFM_01349 5.3e-208 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
NOGEOMFM_01351 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
NOGEOMFM_01352 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
NOGEOMFM_01353 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
NOGEOMFM_01354 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
NOGEOMFM_01355 8.98e-310 steT - - E ko:K03294 - ko00000 amino acid
NOGEOMFM_01356 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NOGEOMFM_01357 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NOGEOMFM_01358 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NOGEOMFM_01360 2.41e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NOGEOMFM_01361 1.16e-178 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
NOGEOMFM_01362 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
NOGEOMFM_01363 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NOGEOMFM_01364 9.02e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NOGEOMFM_01365 1.35e-236 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NOGEOMFM_01366 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
NOGEOMFM_01368 4.26e-228 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
NOGEOMFM_01369 1.24e-259 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
NOGEOMFM_01370 2.56e-219 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NOGEOMFM_01371 7.23e-238 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NOGEOMFM_01372 9.83e-262 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
NOGEOMFM_01373 4.37e-206 ykgA - - E - - - Amidinotransferase
NOGEOMFM_01374 3.82e-120 ykhA - - I - - - Acyl-CoA hydrolase
NOGEOMFM_01375 2.65e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NOGEOMFM_01376 5.85e-13 - - - - - - - -
NOGEOMFM_01377 3.95e-167 ykjA - - S - - - Protein of unknown function (DUF421)
NOGEOMFM_01378 1.57e-128 ykkA - - S - - - Protein of unknown function (DUF664)
NOGEOMFM_01379 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NOGEOMFM_01380 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
NOGEOMFM_01381 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
NOGEOMFM_01382 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NOGEOMFM_01383 3.16e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NOGEOMFM_01384 3.38e-291 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NOGEOMFM_01386 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
NOGEOMFM_01387 1.42e-97 ohrR - - K - - - COG1846 Transcriptional regulators
NOGEOMFM_01388 8.15e-94 ohrB - - O - - - Organic hydroperoxide resistance protein
NOGEOMFM_01389 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
NOGEOMFM_01390 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NOGEOMFM_01391 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NOGEOMFM_01392 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NOGEOMFM_01393 3.65e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NOGEOMFM_01394 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_01395 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NOGEOMFM_01396 2.34e-140 ykoF - - S - - - YKOF-related Family
NOGEOMFM_01397 3.03e-159 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NOGEOMFM_01398 3.13e-309 ykoH - - T - - - Histidine kinase
NOGEOMFM_01399 2.26e-144 ykoI - - S - - - Peptidase propeptide and YPEB domain
NOGEOMFM_01400 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
NOGEOMFM_01401 1.45e-08 - - - - - - - -
NOGEOMFM_01403 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
NOGEOMFM_01404 1.49e-70 tnrA - - K - - - transcriptional
NOGEOMFM_01405 1.63e-25 - - - - - - - -
NOGEOMFM_01406 3.04e-36 ykoL - - - - - - -
NOGEOMFM_01407 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
NOGEOMFM_01408 6.37e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NOGEOMFM_01409 1.44e-128 ykoP - - G - - - polysaccharide deacetylase
NOGEOMFM_01410 4.35e-198 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
NOGEOMFM_01411 0.0 ykoS - - - - - - -
NOGEOMFM_01412 5.72e-239 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
NOGEOMFM_01413 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
NOGEOMFM_01414 1.25e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NOGEOMFM_01415 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
NOGEOMFM_01416 1.71e-143 ykoX - - S - - - membrane-associated protein
NOGEOMFM_01417 1.33e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NOGEOMFM_01418 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NOGEOMFM_01419 1.63e-212 rsgI - - S - - - Anti-sigma factor N-terminus
NOGEOMFM_01420 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
NOGEOMFM_01421 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
NOGEOMFM_01422 9.33e-198 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NOGEOMFM_01423 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
NOGEOMFM_01425 1.77e-28 ykzE - - - - - - -
NOGEOMFM_01426 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
NOGEOMFM_01427 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NOGEOMFM_01428 1.53e-112 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NOGEOMFM_01430 1.33e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NOGEOMFM_01431 2.47e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NOGEOMFM_01432 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NOGEOMFM_01433 2.67e-293 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NOGEOMFM_01434 2.29e-293 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NOGEOMFM_01435 1.77e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NOGEOMFM_01436 1.84e-146 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NOGEOMFM_01437 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NOGEOMFM_01438 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
NOGEOMFM_01440 5.62e-93 eag - - - - - - -
NOGEOMFM_01441 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NOGEOMFM_01442 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
NOGEOMFM_01443 4.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NOGEOMFM_01444 2.01e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NOGEOMFM_01445 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
NOGEOMFM_01446 2.36e-227 ykvI - - S - - - membrane
NOGEOMFM_01447 2.61e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NOGEOMFM_01448 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
NOGEOMFM_01449 2.06e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NOGEOMFM_01450 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NOGEOMFM_01451 2.8e-81 ykvN - - K - - - Transcriptional regulator
NOGEOMFM_01452 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NOGEOMFM_01453 1.82e-273 - - - M - - - Glycosyl transferases group 1
NOGEOMFM_01454 7.56e-48 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
NOGEOMFM_01455 1.75e-204 - - - G - - - Glycosyl hydrolases family 18
NOGEOMFM_01456 8.95e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
NOGEOMFM_01457 5.43e-35 ykvS - - S - - - protein conserved in bacteria
NOGEOMFM_01458 2.5e-39 - - - - - - - -
NOGEOMFM_01459 9.09e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
NOGEOMFM_01460 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NOGEOMFM_01461 1.31e-113 stoA - - CO - - - thiol-disulfide
NOGEOMFM_01462 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NOGEOMFM_01463 3.99e-09 - - - - - - - -
NOGEOMFM_01464 1.93e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NOGEOMFM_01465 6.34e-228 ykvZ - - K - - - Transcriptional regulator
NOGEOMFM_01467 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
NOGEOMFM_01468 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NOGEOMFM_01469 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
NOGEOMFM_01470 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NOGEOMFM_01471 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_01472 2.13e-257 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
NOGEOMFM_01473 1.06e-167 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NOGEOMFM_01474 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NOGEOMFM_01475 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NOGEOMFM_01476 2.97e-169 ykwD - - J - - - protein with SCP PR1 domains
NOGEOMFM_01477 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NOGEOMFM_01478 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NOGEOMFM_01479 3.44e-282 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NOGEOMFM_01480 1.05e-22 - - - - - - - -
NOGEOMFM_01481 2.02e-215 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
NOGEOMFM_01482 3.71e-110 ykyB - - S - - - YkyB-like protein
NOGEOMFM_01483 2.97e-304 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NOGEOMFM_01484 5.84e-115 ykuD - - S - - - protein conserved in bacteria
NOGEOMFM_01485 2.45e-210 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
NOGEOMFM_01486 2.91e-179 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NOGEOMFM_01487 2.05e-297 ykuI - - T - - - Diguanylate phosphodiesterase
NOGEOMFM_01488 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
NOGEOMFM_01489 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
NOGEOMFM_01490 7.83e-38 ykzF - - S - - - Antirepressor AbbA
NOGEOMFM_01491 5.15e-100 ykuL - - S - - - CBS domain
NOGEOMFM_01492 6.52e-216 ccpC - - K - - - Transcriptional regulator
NOGEOMFM_01493 8.34e-109 - - - C ko:K03839 - ko00000 Flavodoxin domain
NOGEOMFM_01494 7.7e-226 ykuO - - - - - - -
NOGEOMFM_01495 6.2e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
NOGEOMFM_01496 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NOGEOMFM_01497 7.66e-274 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NOGEOMFM_01498 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
NOGEOMFM_01499 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
NOGEOMFM_01500 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
NOGEOMFM_01501 1.47e-104 ykuV - - CO - - - thiol-disulfide
NOGEOMFM_01502 4.71e-122 rok - - K - - - Repressor of ComK
NOGEOMFM_01503 2.43e-200 yknT - - - ko:K06437 - ko00000 -
NOGEOMFM_01504 3.75e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NOGEOMFM_01505 1.26e-243 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NOGEOMFM_01506 2.38e-310 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
NOGEOMFM_01507 4.89e-122 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
NOGEOMFM_01508 3.83e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
NOGEOMFM_01509 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NOGEOMFM_01510 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NOGEOMFM_01511 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NOGEOMFM_01512 5.34e-150 yknW - - S - - - Yip1 domain
NOGEOMFM_01513 8.16e-234 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NOGEOMFM_01514 1.44e-158 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_01515 1.58e-264 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NOGEOMFM_01516 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_01517 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
NOGEOMFM_01518 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NOGEOMFM_01519 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NOGEOMFM_01520 5.43e-52 ykoA - - - - - - -
NOGEOMFM_01521 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NOGEOMFM_01522 2.86e-215 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NOGEOMFM_01523 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
NOGEOMFM_01524 1.09e-18 - - - S - - - Uncharacterized protein YkpC
NOGEOMFM_01525 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
NOGEOMFM_01526 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
NOGEOMFM_01527 2.65e-306 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NOGEOMFM_01528 8.06e-197 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
NOGEOMFM_01529 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NOGEOMFM_01530 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NOGEOMFM_01531 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NOGEOMFM_01532 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
NOGEOMFM_01533 4.79e-186 ykrA - - S - - - hydrolases of the HAD superfamily
NOGEOMFM_01534 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NOGEOMFM_01535 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
NOGEOMFM_01536 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
NOGEOMFM_01537 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NOGEOMFM_01538 1.75e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NOGEOMFM_01539 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NOGEOMFM_01540 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NOGEOMFM_01541 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
NOGEOMFM_01542 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
NOGEOMFM_01543 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
NOGEOMFM_01544 1.45e-149 yktB - - S - - - Belongs to the UPF0637 family
NOGEOMFM_01545 4.48e-35 ykzI - - - - - - -
NOGEOMFM_01546 9.48e-195 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
NOGEOMFM_01547 2.98e-100 ykzC - - S - - - Acetyltransferase (GNAT) family
NOGEOMFM_01548 2.88e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NOGEOMFM_01549 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
NOGEOMFM_01550 0.0 ylaA - - - - - - -
NOGEOMFM_01551 1.44e-56 ylaB - - - - - - -
NOGEOMFM_01552 1.45e-114 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NOGEOMFM_01554 1.74e-57 ylaE - - - - - - -
NOGEOMFM_01555 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
NOGEOMFM_01556 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NOGEOMFM_01557 4.4e-63 ylaH - - S - - - YlaH-like protein
NOGEOMFM_01558 8.92e-44 ylaI - - S - - - protein conserved in bacteria
NOGEOMFM_01559 2.97e-127 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NOGEOMFM_01560 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
NOGEOMFM_01561 1.09e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NOGEOMFM_01562 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NOGEOMFM_01563 5.71e-58 ylaN - - S - - - Belongs to the UPF0358 family
NOGEOMFM_01564 2.87e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NOGEOMFM_01565 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NOGEOMFM_01566 1.65e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NOGEOMFM_01567 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NOGEOMFM_01568 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NOGEOMFM_01569 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NOGEOMFM_01570 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NOGEOMFM_01571 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NOGEOMFM_01572 1.04e-214 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
NOGEOMFM_01573 1.61e-81 ylbA - - S - - - YugN-like family
NOGEOMFM_01574 3.09e-97 ylbB - - T - - - COG0517 FOG CBS domain
NOGEOMFM_01575 1.53e-256 ylbC - - S - - - protein with SCP PR1 domains
NOGEOMFM_01576 3.24e-89 ylbD - - S - - - Putative coat protein
NOGEOMFM_01577 1.73e-48 ylbE - - S - - - YlbE-like protein
NOGEOMFM_01578 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
NOGEOMFM_01579 8.8e-52 ylbG - - S - - - UPF0298 protein
NOGEOMFM_01580 1.74e-125 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
NOGEOMFM_01581 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NOGEOMFM_01582 5.5e-282 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
NOGEOMFM_01583 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NOGEOMFM_01584 3.18e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NOGEOMFM_01585 1.05e-294 ylbM - - S - - - Belongs to the UPF0348 family
NOGEOMFM_01587 1.99e-116 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
NOGEOMFM_01588 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NOGEOMFM_01589 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NOGEOMFM_01590 1.33e-115 ylbP - - K - - - n-acetyltransferase
NOGEOMFM_01591 9.62e-216 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NOGEOMFM_01592 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NOGEOMFM_01593 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NOGEOMFM_01594 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NOGEOMFM_01595 3.42e-68 ftsL - - D - - - Essential cell division protein
NOGEOMFM_01596 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NOGEOMFM_01597 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
NOGEOMFM_01598 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NOGEOMFM_01599 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NOGEOMFM_01600 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NOGEOMFM_01601 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NOGEOMFM_01602 4.66e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NOGEOMFM_01603 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
NOGEOMFM_01604 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NOGEOMFM_01605 4.5e-142 ylxW - - S - - - protein conserved in bacteria
NOGEOMFM_01606 1.03e-123 ylxX - - S - - - protein conserved in bacteria
NOGEOMFM_01607 5.37e-76 sbp - - S - - - small basic protein
NOGEOMFM_01608 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NOGEOMFM_01609 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NOGEOMFM_01610 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
NOGEOMFM_01612 1.48e-220 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NOGEOMFM_01613 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NOGEOMFM_01614 1.14e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NOGEOMFM_01615 1.83e-187 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NOGEOMFM_01616 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
NOGEOMFM_01617 3.58e-51 ylmC - - S - - - sporulation protein
NOGEOMFM_01618 7.23e-201 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
NOGEOMFM_01619 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NOGEOMFM_01620 4.47e-87 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NOGEOMFM_01621 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
NOGEOMFM_01622 3.67e-179 ylmH - - S - - - conserved protein, contains S4-like domain
NOGEOMFM_01623 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
NOGEOMFM_01624 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NOGEOMFM_01625 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
NOGEOMFM_01626 5.47e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NOGEOMFM_01627 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NOGEOMFM_01628 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NOGEOMFM_01629 3.71e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
NOGEOMFM_01630 1.04e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NOGEOMFM_01631 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NOGEOMFM_01632 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
NOGEOMFM_01633 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
NOGEOMFM_01634 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NOGEOMFM_01635 1.22e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NOGEOMFM_01636 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NOGEOMFM_01637 1.27e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NOGEOMFM_01639 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
NOGEOMFM_01640 6.01e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
NOGEOMFM_01641 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
NOGEOMFM_01642 3.76e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NOGEOMFM_01643 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
NOGEOMFM_01644 1.45e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
NOGEOMFM_01645 1.08e-106 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
NOGEOMFM_01646 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
NOGEOMFM_01647 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
NOGEOMFM_01648 8.41e-202 yloC - - S - - - stress-induced protein
NOGEOMFM_01649 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
NOGEOMFM_01650 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NOGEOMFM_01651 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NOGEOMFM_01652 2.96e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NOGEOMFM_01653 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NOGEOMFM_01654 8.3e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NOGEOMFM_01655 1.28e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NOGEOMFM_01656 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NOGEOMFM_01657 5.3e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NOGEOMFM_01658 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NOGEOMFM_01659 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NOGEOMFM_01660 3.92e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NOGEOMFM_01661 1.1e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NOGEOMFM_01662 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NOGEOMFM_01663 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NOGEOMFM_01664 3.65e-78 yloU - - S - - - protein conserved in bacteria
NOGEOMFM_01665 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
NOGEOMFM_01666 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NOGEOMFM_01667 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
NOGEOMFM_01668 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NOGEOMFM_01669 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NOGEOMFM_01670 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NOGEOMFM_01671 1.79e-216 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NOGEOMFM_01672 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NOGEOMFM_01673 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NOGEOMFM_01674 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NOGEOMFM_01675 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NOGEOMFM_01676 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NOGEOMFM_01677 1.67e-114 - - - - - - - -
NOGEOMFM_01678 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NOGEOMFM_01679 9.7e-309 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NOGEOMFM_01680 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NOGEOMFM_01681 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NOGEOMFM_01682 3.41e-80 ylqD - - S - - - YlqD protein
NOGEOMFM_01683 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NOGEOMFM_01684 2.41e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NOGEOMFM_01685 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NOGEOMFM_01686 4.89e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NOGEOMFM_01687 2.89e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NOGEOMFM_01688 0.0 ylqG - - - - - - -
NOGEOMFM_01689 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
NOGEOMFM_01690 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NOGEOMFM_01691 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NOGEOMFM_01692 2.66e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
NOGEOMFM_01693 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NOGEOMFM_01694 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NOGEOMFM_01695 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
NOGEOMFM_01696 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NOGEOMFM_01697 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NOGEOMFM_01698 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NOGEOMFM_01699 3.27e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NOGEOMFM_01700 7.54e-99 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
NOGEOMFM_01701 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
NOGEOMFM_01702 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
NOGEOMFM_01703 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NOGEOMFM_01704 1.92e-144 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
NOGEOMFM_01705 1.22e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NOGEOMFM_01706 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
NOGEOMFM_01707 5.08e-84 ylxF - - S - - - MgtE intracellular N domain
NOGEOMFM_01708 1.28e-311 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
NOGEOMFM_01709 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
NOGEOMFM_01710 1.09e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
NOGEOMFM_01711 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
NOGEOMFM_01712 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NOGEOMFM_01713 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NOGEOMFM_01714 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
NOGEOMFM_01715 7.87e-137 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
NOGEOMFM_01716 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
NOGEOMFM_01717 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
NOGEOMFM_01718 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
NOGEOMFM_01719 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NOGEOMFM_01720 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NOGEOMFM_01721 5.65e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
NOGEOMFM_01722 1.09e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
NOGEOMFM_01723 2.58e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NOGEOMFM_01724 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
NOGEOMFM_01725 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
NOGEOMFM_01726 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NOGEOMFM_01727 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NOGEOMFM_01728 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NOGEOMFM_01729 6.62e-99 ylxL - - - - - - -
NOGEOMFM_01730 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NOGEOMFM_01731 5.68e-201 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NOGEOMFM_01732 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NOGEOMFM_01733 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NOGEOMFM_01734 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NOGEOMFM_01735 1.36e-177 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NOGEOMFM_01736 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NOGEOMFM_01737 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NOGEOMFM_01738 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NOGEOMFM_01739 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NOGEOMFM_01740 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NOGEOMFM_01741 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NOGEOMFM_01742 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
NOGEOMFM_01743 6.16e-63 ylxQ - - J - - - ribosomal protein
NOGEOMFM_01744 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NOGEOMFM_01745 7.83e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
NOGEOMFM_01746 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NOGEOMFM_01747 1.17e-217 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NOGEOMFM_01748 3.84e-231 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NOGEOMFM_01749 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NOGEOMFM_01750 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NOGEOMFM_01751 3.98e-230 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
NOGEOMFM_01752 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
NOGEOMFM_01753 1.53e-56 ymxH - - S - - - YlmC YmxH family
NOGEOMFM_01754 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
NOGEOMFM_01755 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NOGEOMFM_01756 4.77e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NOGEOMFM_01757 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NOGEOMFM_01758 9.08e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NOGEOMFM_01759 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NOGEOMFM_01760 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
NOGEOMFM_01761 4.94e-44 - - - S - - - YlzJ-like protein
NOGEOMFM_01762 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NOGEOMFM_01763 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_01764 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NOGEOMFM_01765 1.35e-298 albE - - S - - - Peptidase M16
NOGEOMFM_01766 6.8e-309 ymfH - - S - - - zinc protease
NOGEOMFM_01767 1.49e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NOGEOMFM_01768 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
NOGEOMFM_01769 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
NOGEOMFM_01770 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
NOGEOMFM_01771 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NOGEOMFM_01772 4.33e-299 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NOGEOMFM_01773 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NOGEOMFM_01774 2.82e-280 pbpX - - V - - - Beta-lactamase
NOGEOMFM_01775 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NOGEOMFM_01776 5.08e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
NOGEOMFM_01777 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
NOGEOMFM_01778 7.12e-254 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NOGEOMFM_01779 2.4e-277 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NOGEOMFM_01780 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NOGEOMFM_01781 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
NOGEOMFM_01782 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
NOGEOMFM_01783 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NOGEOMFM_01784 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NOGEOMFM_01785 2.93e-92 - - - S - - - Regulatory protein YrvL
NOGEOMFM_01787 1.13e-126 ymcC - - S - - - Membrane
NOGEOMFM_01788 3.43e-140 pksA - - K - - - Transcriptional regulator
NOGEOMFM_01789 9.47e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
NOGEOMFM_01790 1.78e-206 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NOGEOMFM_01792 1.64e-236 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
NOGEOMFM_01793 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
NOGEOMFM_01794 5.46e-51 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
NOGEOMFM_01795 4.36e-303 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NOGEOMFM_01796 9.7e-314 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
NOGEOMFM_01797 2.04e-183 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
NOGEOMFM_01798 1.75e-173 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
NOGEOMFM_01799 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NOGEOMFM_01800 0.0 - - - Q ko:K13612 - ko00000,ko01004,ko01008 Polyketide synthase of type I
NOGEOMFM_01801 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NOGEOMFM_01802 0.0 - - - IQ ko:K13611,ko:K13613,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
NOGEOMFM_01803 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
NOGEOMFM_01804 9.72e-295 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NOGEOMFM_01805 9.39e-80 ymzB - - - - - - -
NOGEOMFM_01806 7.65e-207 - - - S - - - Metallo-beta-lactamase superfamily
NOGEOMFM_01807 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
NOGEOMFM_01809 3.96e-163 ymaC - - S - - - Replication protein
NOGEOMFM_01810 8.49e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
NOGEOMFM_01811 6.39e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
NOGEOMFM_01812 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NOGEOMFM_01814 5.41e-76 ymaF - - S - - - YmaF family
NOGEOMFM_01815 3.95e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NOGEOMFM_01816 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NOGEOMFM_01817 1.63e-31 - - - - - - - -
NOGEOMFM_01818 1.2e-30 ymzA - - - - - - -
NOGEOMFM_01819 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
NOGEOMFM_01820 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NOGEOMFM_01821 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NOGEOMFM_01822 2.24e-141 - - - - - - - -
NOGEOMFM_01823 2e-150 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NOGEOMFM_01824 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
NOGEOMFM_01825 2.12e-292 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NOGEOMFM_01826 1.95e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NOGEOMFM_01827 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
NOGEOMFM_01828 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NOGEOMFM_01829 4.61e-47 - - - L - - - Arm DNA-binding domain
NOGEOMFM_01830 9.44e-127 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 replicative DNA helicase
NOGEOMFM_01831 3.5e-30 - - - - - - - -
NOGEOMFM_01834 4.9e-66 - - - M - - - ArpU family transcriptional regulator
NOGEOMFM_01835 1.82e-31 - - - S - - - FRG
NOGEOMFM_01836 1.4e-86 - - - S - - - regulation of transcription, DNA-dependent
NOGEOMFM_01837 4.25e-25 - - - N - - - HicA toxin of bacterial toxin-antitoxin,
NOGEOMFM_01842 1.89e-63 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
NOGEOMFM_01843 6.85e-103 - - - L - - - phage terminase small subunit
NOGEOMFM_01844 1.7e-34 - - - S - - - Terminase
NOGEOMFM_01847 4.18e-14 - - - - - - - -
NOGEOMFM_01850 2.26e-118 - - - M - - - Glycosyltransferase like family
NOGEOMFM_01851 7.89e-154 - - - H - - - Methionine biosynthesis protein MetW
NOGEOMFM_01852 1.03e-240 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
NOGEOMFM_01853 1.56e-274 - - - H - - - N-terminal domain of galactosyltransferase
NOGEOMFM_01855 3.38e-125 ynaD - - J - - - Acetyltransferase (GNAT) domain
NOGEOMFM_01857 3.45e-90 - - - S - - - CAAX protease self-immunity
NOGEOMFM_01858 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NOGEOMFM_01859 2.79e-30 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NOGEOMFM_01860 1.1e-142 - - - S - - - Domain of unknown function (DUF3885)
NOGEOMFM_01861 1.14e-61 ynaF - - - - - - -
NOGEOMFM_01863 1.76e-109 - - - E - - - phosphoribosylanthranilate isomerase activity
NOGEOMFM_01864 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
NOGEOMFM_01865 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NOGEOMFM_01866 5.85e-274 xylR - - GK - - - ROK family
NOGEOMFM_01867 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
NOGEOMFM_01868 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
NOGEOMFM_01869 2.06e-144 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
NOGEOMFM_01870 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NOGEOMFM_01871 5.06e-280 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NOGEOMFM_01872 3.86e-107 - - - S - - - Protein of unknown function (DUF2691)
NOGEOMFM_01873 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
NOGEOMFM_01874 7.54e-22 - - - - - - - -
NOGEOMFM_01877 2.75e-210 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NOGEOMFM_01879 4.44e-172 - - - S - - - Domain of unknown function, YrpD
NOGEOMFM_01882 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
NOGEOMFM_01883 8.92e-96 - - - - - - - -
NOGEOMFM_01884 1.05e-102 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
NOGEOMFM_01887 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NOGEOMFM_01888 1.95e-250 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
NOGEOMFM_01889 5.57e-289 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
NOGEOMFM_01890 1.85e-198 yndG - - S - - - DoxX-like family
NOGEOMFM_01891 3.46e-149 - - - S - - - Domain of unknown function (DUF4166)
NOGEOMFM_01892 0.0 yndJ - - S - - - YndJ-like protein
NOGEOMFM_01894 3.26e-175 yndL - - S - - - Replication protein
NOGEOMFM_01895 1.32e-96 yndM - - S - - - Protein of unknown function (DUF2512)
NOGEOMFM_01896 4.44e-104 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NOGEOMFM_01897 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NOGEOMFM_01898 2.44e-64 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NOGEOMFM_01899 2.29e-144 yneB - - L - - - resolvase
NOGEOMFM_01900 1.15e-43 ynzC - - S - - - UPF0291 protein
NOGEOMFM_01901 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NOGEOMFM_01902 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
NOGEOMFM_01903 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
NOGEOMFM_01904 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
NOGEOMFM_01905 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
NOGEOMFM_01906 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
NOGEOMFM_01907 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
NOGEOMFM_01908 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
NOGEOMFM_01909 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
NOGEOMFM_01910 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
NOGEOMFM_01911 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
NOGEOMFM_01912 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NOGEOMFM_01913 2.53e-118 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NOGEOMFM_01914 9.26e-10 - - - S - - - Fur-regulated basic protein B
NOGEOMFM_01916 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
NOGEOMFM_01917 1.64e-94 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
NOGEOMFM_01918 2.32e-71 yneQ - - - - - - -
NOGEOMFM_01919 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
NOGEOMFM_01920 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NOGEOMFM_01921 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
NOGEOMFM_01922 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NOGEOMFM_01923 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NOGEOMFM_01924 1.82e-18 - - - - - - - -
NOGEOMFM_01925 1.06e-75 ynfC - - - - - - -
NOGEOMFM_01926 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
NOGEOMFM_01927 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
NOGEOMFM_01929 9.85e-317 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
NOGEOMFM_01930 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NOGEOMFM_01931 4.06e-102 yngA - - S - - - membrane
NOGEOMFM_01932 7.53e-208 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NOGEOMFM_01933 2.01e-134 yngC - - S - - - membrane-associated protein
NOGEOMFM_01934 7.39e-296 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
NOGEOMFM_01935 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NOGEOMFM_01936 1.42e-173 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
NOGEOMFM_01937 3.89e-211 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
NOGEOMFM_01938 1.19e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
NOGEOMFM_01939 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
NOGEOMFM_01940 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NOGEOMFM_01941 7.28e-266 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NOGEOMFM_01942 2.97e-07 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
NOGEOMFM_01943 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
NOGEOMFM_01944 2.48e-83 yngL - - S - - - Protein of unknown function (DUF1360)
NOGEOMFM_01945 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
NOGEOMFM_01946 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NOGEOMFM_01947 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NOGEOMFM_01948 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NOGEOMFM_01949 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NOGEOMFM_01950 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
NOGEOMFM_01951 9.53e-241 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NOGEOMFM_01952 1.33e-310 yoeA - - V - - - MATE efflux family protein
NOGEOMFM_01953 4.13e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
NOGEOMFM_01955 1.14e-124 - - - L - - - Integrase
NOGEOMFM_01956 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
NOGEOMFM_01957 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NOGEOMFM_01958 1.3e-202 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_01959 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NOGEOMFM_01960 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NOGEOMFM_01961 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
NOGEOMFM_01962 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_01963 1.91e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NOGEOMFM_01964 2.24e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NOGEOMFM_01965 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NOGEOMFM_01966 7.3e-156 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NOGEOMFM_01967 1.7e-54 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
NOGEOMFM_01968 5.79e-171 yoxB - - - - - - -
NOGEOMFM_01969 7.43e-119 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NOGEOMFM_01970 1.7e-300 - - - S - - - Arylsulfotransferase (ASST)
NOGEOMFM_01971 2.75e-160 - 3.1.1.3 - I ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 Lipase (class 3)
NOGEOMFM_01972 1.84e-299 yoaB - - EGP - - - the major facilitator superfamily
NOGEOMFM_01973 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
NOGEOMFM_01974 3.36e-234 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NOGEOMFM_01975 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NOGEOMFM_01976 7.24e-45 yoaF - - - - - - -
NOGEOMFM_01979 1.46e-19 - - - - - - - -
NOGEOMFM_01980 2.99e-55 - - - S - - - Protein of unknown function (DUF4025)
NOGEOMFM_01981 6.22e-308 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
NOGEOMFM_01982 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
NOGEOMFM_01983 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
NOGEOMFM_01984 1.79e-145 yoaK - - S - - - Membrane
NOGEOMFM_01985 1.43e-252 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
NOGEOMFM_01986 2.07e-170 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
NOGEOMFM_01989 8.89e-293 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NOGEOMFM_01991 3.86e-183 yoaP - - K - - - YoaP-like
NOGEOMFM_01992 3.01e-87 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
NOGEOMFM_01994 1.87e-113 - - - - - - - -
NOGEOMFM_01995 1.04e-217 yoaR - - V - - - vancomycin resistance protein
NOGEOMFM_01996 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
NOGEOMFM_01997 7.19e-41 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_01998 1.57e-188 yoaT - - S - - - Protein of unknown function (DUF817)
NOGEOMFM_01999 1.11e-201 yoaU - - K - - - LysR substrate binding domain
NOGEOMFM_02000 3.7e-201 yoaV - - EG - - - EamA-like transporter family
NOGEOMFM_02001 1.89e-100 yoaW - - - - - - -
NOGEOMFM_02002 5.94e-148 lin0465 - - S - - - DJ-1/PfpI family
NOGEOMFM_02003 2.09e-214 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
NOGEOMFM_02006 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
NOGEOMFM_02007 1.07e-156 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
NOGEOMFM_02008 1e-47 - - - S - - - TM2 domain
NOGEOMFM_02009 7.63e-74 - - - K - - - Helix-turn-helix
NOGEOMFM_02012 7.44e-66 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
NOGEOMFM_02017 1.56e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NOGEOMFM_02021 6.81e-66 - - - S - - - Tetratricopeptide repeat
NOGEOMFM_02022 2.51e-74 - - - J - - - tRNA cytidylyltransferase activity
NOGEOMFM_02030 8.49e-265 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NOGEOMFM_02032 4.52e-201 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NOGEOMFM_02033 2.36e-44 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NOGEOMFM_02034 1.43e-64 - - - - - - - -
NOGEOMFM_02036 5.21e-26 - - - - - - - -
NOGEOMFM_02037 8.94e-13 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NOGEOMFM_02038 3.93e-117 yokH - - G - - - SMI1 / KNR4 family
NOGEOMFM_02039 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
NOGEOMFM_02040 5.21e-71 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
NOGEOMFM_02041 6.11e-174 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
NOGEOMFM_02042 3.05e-182 - - - J - - - FR47-like protein
NOGEOMFM_02043 1.53e-127 yobS - - K - - - Transcriptional regulator
NOGEOMFM_02044 3.16e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NOGEOMFM_02045 1.01e-110 - - - K - - - Bacterial transcription activator, effector binding domain
NOGEOMFM_02046 2.3e-226 yobV - - K - - - WYL domain
NOGEOMFM_02047 3.01e-120 yobW - - - - - - -
NOGEOMFM_02048 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
NOGEOMFM_02049 2.89e-151 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NOGEOMFM_02050 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
NOGEOMFM_02051 2.49e-183 - - - - - - - -
NOGEOMFM_02052 1.08e-121 yocC - - - - - - -
NOGEOMFM_02053 6.71e-241 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
NOGEOMFM_02054 5.67e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
NOGEOMFM_02055 3.51e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NOGEOMFM_02056 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NOGEOMFM_02057 1.67e-174 yocH - - M - - - COG1388 FOG LysM repeat
NOGEOMFM_02058 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NOGEOMFM_02059 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NOGEOMFM_02060 4.07e-107 yocK - - T - - - general stress protein
NOGEOMFM_02061 3.02e-70 yocL - - - - - - -
NOGEOMFM_02062 3.93e-41 - - - - - - - -
NOGEOMFM_02063 2.21e-113 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NOGEOMFM_02064 2.94e-55 yozN - - - - - - -
NOGEOMFM_02065 1.83e-49 yocN - - - - - - -
NOGEOMFM_02066 2.17e-74 yozO - - S - - - Bacterial PH domain
NOGEOMFM_02067 1.91e-42 yozC - - - - - - -
NOGEOMFM_02068 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NOGEOMFM_02069 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
NOGEOMFM_02070 3.91e-211 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
NOGEOMFM_02071 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NOGEOMFM_02072 4.5e-212 yocS - - S ko:K03453 - ko00000 -transporter
NOGEOMFM_02073 2.59e-264 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NOGEOMFM_02074 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NOGEOMFM_02075 0.0 yojO - - P - - - Von Willebrand factor
NOGEOMFM_02076 3.82e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
NOGEOMFM_02077 7.31e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NOGEOMFM_02078 7.5e-267 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
NOGEOMFM_02079 1.13e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
NOGEOMFM_02080 1.19e-138 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NOGEOMFM_02082 2.06e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
NOGEOMFM_02083 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NOGEOMFM_02084 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
NOGEOMFM_02085 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
NOGEOMFM_02086 1.07e-57 - - - - - - - -
NOGEOMFM_02087 2.84e-208 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
NOGEOMFM_02088 7.69e-100 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
NOGEOMFM_02089 5.59e-14 - - - - - - - -
NOGEOMFM_02090 1.6e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
NOGEOMFM_02091 3.97e-84 iolK - - S - - - tautomerase
NOGEOMFM_02092 2.63e-73 yodB - - K - - - transcriptional
NOGEOMFM_02093 1.11e-139 yodC - - C - - - nitroreductase
NOGEOMFM_02094 8.86e-145 yahD - - S ko:K06999 - ko00000 Carboxylesterase
NOGEOMFM_02095 3.24e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
NOGEOMFM_02096 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
NOGEOMFM_02097 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NOGEOMFM_02098 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NOGEOMFM_02099 3.69e-167 yodH - - Q - - - Methyltransferase
NOGEOMFM_02100 8.39e-42 yodI - - - - - - -
NOGEOMFM_02101 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
NOGEOMFM_02102 1.19e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
NOGEOMFM_02103 2.08e-12 - - - - - - - -
NOGEOMFM_02104 1.17e-71 yodL - - S - - - YodL-like
NOGEOMFM_02105 2.14e-133 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
NOGEOMFM_02106 5.18e-34 yozD - - S - - - YozD-like protein
NOGEOMFM_02108 1.29e-159 yodN - - - - - - -
NOGEOMFM_02109 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
NOGEOMFM_02110 1.4e-62 yokU - - S - - - YokU-like protein, putative antitoxin
NOGEOMFM_02111 2.43e-65 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
NOGEOMFM_02112 4.3e-54 - - - S - - - Domain of unknown function (DUF4652)
NOGEOMFM_02115 1.11e-40 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NOGEOMFM_02117 4.12e-118 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NOGEOMFM_02120 2.22e-40 - - - S - - - Macro domain
NOGEOMFM_02130 1.84e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
NOGEOMFM_02134 1.35e-44 - - - - - - - -
NOGEOMFM_02136 3.29e-39 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NOGEOMFM_02137 3.08e-207 - - - S - - - Thymidylate synthase
NOGEOMFM_02141 1.71e-17 XK27_09885 - - V - - - COG4767 Glycopeptide antibiotics resistance protein
NOGEOMFM_02142 2.56e-98 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
NOGEOMFM_02143 3.21e-49 - - - O - - - Glutaredoxin
NOGEOMFM_02144 4.35e-125 - - - L - - - HNH endonuclease
NOGEOMFM_02145 1.44e-135 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NOGEOMFM_02147 1.88e-251 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NOGEOMFM_02148 3.83e-43 - - - L - - - GIY-YIG catalytic domain
NOGEOMFM_02149 1.15e-157 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NOGEOMFM_02150 3.12e-82 - - - S - - - NrdI Flavodoxin like
NOGEOMFM_02169 1.82e-101 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
NOGEOMFM_02170 2.42e-117 yorS - - S - - - 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
NOGEOMFM_02171 1.47e-110 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
NOGEOMFM_02176 1.09e-136 - - - S - - - protein conserved in bacteria
NOGEOMFM_02177 0.0 - 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NOGEOMFM_02178 0.0 - - - S - - - Bacterial DNA polymerase III alpha subunit
NOGEOMFM_02179 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NOGEOMFM_02180 7.79e-285 - - - L - - - DNA primase activity
NOGEOMFM_02181 0.0 - - - J - - - DnaB-like helicase C terminal domain
NOGEOMFM_02182 7.45e-111 - - - - - - - -
NOGEOMFM_02183 6.35e-229 - - - L - - - AAA domain
NOGEOMFM_02184 1.26e-214 - - - - - - - -
NOGEOMFM_02188 0.0 - - - M - - - Parallel beta-helix repeats
NOGEOMFM_02189 6.44e-177 - - - S - - - Pfam:DUF867
NOGEOMFM_02191 2.39e-26 - - - S - - - YopX protein
NOGEOMFM_02193 7.21e-165 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
NOGEOMFM_02194 8.69e-189 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
NOGEOMFM_02199 6.72e-94 - - - - - - - -
NOGEOMFM_02202 1.78e-56 - - - - - - - -
NOGEOMFM_02207 2.65e-15 - - - S - - - Protein of unknown function (DUF2815)
NOGEOMFM_02208 3.18e-84 - - - N - - - bacterial-type flagellum assembly
NOGEOMFM_02213 8.82e-22 - - - - - - - -
NOGEOMFM_02219 4.78e-46 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_02220 6.81e-225 - - - - - - - -
NOGEOMFM_02221 0.0 - - - S - - - DNA-sulfur modification-associated
NOGEOMFM_02222 2.9e-254 - - - L - - - Belongs to the 'phage' integrase family
NOGEOMFM_02227 1.6e-134 - - - - - - - -
NOGEOMFM_02230 7.69e-08 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil DNA glycosylase superfamily
NOGEOMFM_02235 1.56e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NOGEOMFM_02239 3.17e-23 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NOGEOMFM_02240 4.98e-106 yoaW - - - - - - -
NOGEOMFM_02241 7.83e-08 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NOGEOMFM_02242 6.01e-96 - - - - - - - -
NOGEOMFM_02248 5.79e-258 - - - - - - - -
NOGEOMFM_02251 0.0 - - - - - - - -
NOGEOMFM_02252 1.17e-47 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NOGEOMFM_02253 1.21e-257 - - - - - - - -
NOGEOMFM_02256 2.96e-267 - - - S - - - Calcineurin-like phosphoesterase superfamily domain
NOGEOMFM_02258 1.64e-85 - - - - - - - -
NOGEOMFM_02259 6.98e-225 - - - - - - - -
NOGEOMFM_02260 0.0 - - - - - - - -
NOGEOMFM_02261 0.0 - - - - - - - -
NOGEOMFM_02262 7.15e-122 - - - - - - - -
NOGEOMFM_02263 9.83e-236 - - - - - - - -
NOGEOMFM_02264 2.31e-105 - - - - - - - -
NOGEOMFM_02265 1.22e-88 - - - - - - - -
NOGEOMFM_02267 5.49e-156 - - - - - - - -
NOGEOMFM_02268 3.16e-102 - - - - - - - -
NOGEOMFM_02269 1.09e-115 - - - - - - - -
NOGEOMFM_02270 6.41e-75 - - - - - - - -
NOGEOMFM_02273 1.56e-69 - - - - - - - -
NOGEOMFM_02274 5.87e-33 - - - - - - - -
NOGEOMFM_02277 1.12e-110 - - - - - - - -
NOGEOMFM_02278 3.06e-89 - - - - - - - -
NOGEOMFM_02279 4.75e-245 - - - A - - - Belongs to the 'phage' integrase family
NOGEOMFM_02280 3.31e-52 - - - K - - - Helix-turn-helix
NOGEOMFM_02281 1.55e-66 - - - - - - - -
NOGEOMFM_02282 0.0 - - - S - - - peptidoglycan catabolic process
NOGEOMFM_02283 2.48e-106 - - - S - - - Phage tail protein
NOGEOMFM_02284 0.0 - - - S - - - Pfam Transposase IS66
NOGEOMFM_02285 6.68e-143 - - - - - - - -
NOGEOMFM_02286 2.12e-55 - - - S - - - virus tail, fiber
NOGEOMFM_02287 3.07e-111 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
NOGEOMFM_02289 3.98e-49 - - - S - - - Bacteriophage holin
NOGEOMFM_02290 1.29e-125 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NOGEOMFM_02292 4.81e-53 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NOGEOMFM_02294 4.01e-33 - 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
NOGEOMFM_02295 2.14e-17 - - - Q - - - methyltransferase
NOGEOMFM_02297 1.19e-296 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NOGEOMFM_02298 2.9e-68 - - - S - - - YolD-like protein
NOGEOMFM_02300 5.23e-49 - - - - - - - -
NOGEOMFM_02304 1.76e-126 - - - J - - - Acetyltransferase (GNAT) domain
NOGEOMFM_02305 3.47e-129 yokK - - S - - - SMI1 / KNR4 family
NOGEOMFM_02306 1.25e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
NOGEOMFM_02307 1.87e-43 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NOGEOMFM_02308 7e-289 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NOGEOMFM_02309 1.42e-167 - - - V - - - HNH endonuclease
NOGEOMFM_02310 3.69e-85 - - - G - - - SMI1-KNR4 cell-wall
NOGEOMFM_02311 8.25e-168 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
NOGEOMFM_02312 9.2e-104 - - - S ko:K03824 - ko00000,ko01000 family acetyltransferase
NOGEOMFM_02313 0.0 - - - S - - - Recombinase
NOGEOMFM_02314 1.36e-251 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
NOGEOMFM_02315 1.84e-197 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
NOGEOMFM_02316 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
NOGEOMFM_02317 2.71e-152 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NOGEOMFM_02318 3.27e-159 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NOGEOMFM_02319 2.34e-315 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NOGEOMFM_02321 9.78e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
NOGEOMFM_02322 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
NOGEOMFM_02323 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
NOGEOMFM_02324 1.12e-85 cgeA - - - ko:K06319 - ko00000 -
NOGEOMFM_02325 4.7e-237 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
NOGEOMFM_02326 2.31e-279 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
NOGEOMFM_02327 4.75e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NOGEOMFM_02328 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NOGEOMFM_02329 1.4e-132 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NOGEOMFM_02330 4.14e-94 ypoP - - K - - - transcriptional
NOGEOMFM_02331 9.99e-290 mepA - - V - - - MATE efflux family protein
NOGEOMFM_02332 2.13e-40 ypmT - - S - - - Uncharacterized ympT
NOGEOMFM_02333 6.8e-129 ypmS - - S - - - protein conserved in bacteria
NOGEOMFM_02334 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
NOGEOMFM_02335 2.77e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NOGEOMFM_02336 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
NOGEOMFM_02337 3.64e-310 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NOGEOMFM_02338 1.4e-236 yplP - - K - - - Transcriptional regulator
NOGEOMFM_02339 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
NOGEOMFM_02340 1.71e-145 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NOGEOMFM_02341 1.21e-124 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NOGEOMFM_02342 7.27e-203 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NOGEOMFM_02343 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
NOGEOMFM_02344 3.47e-148 ypjP - - S - - - YpjP-like protein
NOGEOMFM_02345 6.15e-187 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
NOGEOMFM_02346 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
NOGEOMFM_02347 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
NOGEOMFM_02348 8.52e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
NOGEOMFM_02349 3.3e-138 yagB - - S ko:K06950 - ko00000 phosphohydrolase
NOGEOMFM_02350 3.13e-114 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
NOGEOMFM_02351 1.28e-226 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NOGEOMFM_02352 4.89e-63 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NOGEOMFM_02353 4.02e-199 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NOGEOMFM_02354 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
NOGEOMFM_02355 1.17e-22 degR - - - - - - -
NOGEOMFM_02356 5.22e-41 - - - S - - - Protein of unknown function (DUF2564)
NOGEOMFM_02357 7.99e-41 ypeQ - - S - - - Zinc-finger
NOGEOMFM_02358 6.45e-173 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
NOGEOMFM_02359 3.27e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NOGEOMFM_02360 7.64e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
NOGEOMFM_02361 5.23e-05 - - - - ko:K06429 - ko00000 -
NOGEOMFM_02362 2.26e-213 ypcP - - L - - - 5'3' exonuclease
NOGEOMFM_02363 1.08e-11 - - - - - - - -
NOGEOMFM_02364 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
NOGEOMFM_02365 0.0 ypbR - - S - - - Dynamin family
NOGEOMFM_02366 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
NOGEOMFM_02367 2.07e-262 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
NOGEOMFM_02368 3.51e-291 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
NOGEOMFM_02369 1.65e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NOGEOMFM_02370 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NOGEOMFM_02371 4.09e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NOGEOMFM_02372 1.47e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
NOGEOMFM_02373 2.83e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
NOGEOMFM_02374 4.51e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
NOGEOMFM_02375 1.2e-202 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NOGEOMFM_02376 1.88e-175 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NOGEOMFM_02377 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
NOGEOMFM_02379 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NOGEOMFM_02380 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NOGEOMFM_02381 9.4e-128 ypsA - - S - - - Belongs to the UPF0398 family
NOGEOMFM_02382 9.82e-299 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
NOGEOMFM_02383 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NOGEOMFM_02384 1.34e-112 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
NOGEOMFM_02385 4.33e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NOGEOMFM_02386 8.72e-68 yppG - - S - - - YppG-like protein
NOGEOMFM_02387 2.27e-11 - - - S - - - YppF-like protein
NOGEOMFM_02388 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
NOGEOMFM_02391 1.03e-237 yppC - - S - - - Protein of unknown function (DUF2515)
NOGEOMFM_02392 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NOGEOMFM_02393 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NOGEOMFM_02394 1.17e-120 ypoC - - - - - - -
NOGEOMFM_02395 5.92e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NOGEOMFM_02396 1.9e-164 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
NOGEOMFM_02397 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
NOGEOMFM_02398 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
NOGEOMFM_02399 2.27e-103 ypmB - - S - - - protein conserved in bacteria
NOGEOMFM_02400 6.21e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
NOGEOMFM_02401 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NOGEOMFM_02402 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NOGEOMFM_02403 2.23e-199 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NOGEOMFM_02404 9.39e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NOGEOMFM_02405 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NOGEOMFM_02406 3.7e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NOGEOMFM_02407 1.65e-265 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
NOGEOMFM_02408 2.21e-165 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
NOGEOMFM_02409 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
NOGEOMFM_02410 6.89e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NOGEOMFM_02411 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
NOGEOMFM_02412 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NOGEOMFM_02413 6.84e-183 ypjB - - S - - - sporulation protein
NOGEOMFM_02414 1.15e-125 ypjA - - S - - - membrane
NOGEOMFM_02415 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
NOGEOMFM_02416 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
NOGEOMFM_02417 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
NOGEOMFM_02418 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
NOGEOMFM_02419 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
NOGEOMFM_02420 8.74e-298 ypiA - - S - - - COG0457 FOG TPR repeat
NOGEOMFM_02421 1.64e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NOGEOMFM_02422 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
NOGEOMFM_02423 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NOGEOMFM_02424 5.43e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NOGEOMFM_02425 3.12e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NOGEOMFM_02426 5.25e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
NOGEOMFM_02427 2.82e-143 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NOGEOMFM_02428 2.48e-229 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NOGEOMFM_02429 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NOGEOMFM_02430 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NOGEOMFM_02431 7.79e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NOGEOMFM_02432 5.88e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NOGEOMFM_02433 2.13e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
NOGEOMFM_02434 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NOGEOMFM_02435 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NOGEOMFM_02436 3.84e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NOGEOMFM_02437 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NOGEOMFM_02438 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NOGEOMFM_02439 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
NOGEOMFM_02440 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NOGEOMFM_02441 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NOGEOMFM_02442 2.5e-175 yphF - - - - - - -
NOGEOMFM_02443 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
NOGEOMFM_02444 6.32e-231 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NOGEOMFM_02445 1.72e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NOGEOMFM_02446 5.91e-38 ypzH - - - - - - -
NOGEOMFM_02447 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
NOGEOMFM_02448 3.87e-134 yphA - - - - - - -
NOGEOMFM_02449 5.6e-12 - - - S - - - YpzI-like protein
NOGEOMFM_02450 1.1e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NOGEOMFM_02451 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NOGEOMFM_02452 3.91e-144 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NOGEOMFM_02453 2.48e-32 - - - S - - - Family of unknown function (DUF5359)
NOGEOMFM_02454 8.95e-142 ypfA - - M - - - Flagellar protein YcgR
NOGEOMFM_02455 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
NOGEOMFM_02456 1.1e-204 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
NOGEOMFM_02457 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
NOGEOMFM_02458 4.25e-223 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
NOGEOMFM_02459 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NOGEOMFM_02460 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NOGEOMFM_02461 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
NOGEOMFM_02462 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
NOGEOMFM_02463 4.22e-139 ypbE - - M - - - Lysin motif
NOGEOMFM_02464 6.13e-129 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
NOGEOMFM_02465 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
NOGEOMFM_02466 5.67e-258 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
NOGEOMFM_02467 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
NOGEOMFM_02468 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NOGEOMFM_02469 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NOGEOMFM_02470 3.37e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NOGEOMFM_02471 1.49e-254 rsiX - - - - - - -
NOGEOMFM_02472 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NOGEOMFM_02473 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NOGEOMFM_02474 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NOGEOMFM_02475 1.34e-278 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NOGEOMFM_02476 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
NOGEOMFM_02477 8.71e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NOGEOMFM_02478 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NOGEOMFM_02479 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
NOGEOMFM_02480 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
NOGEOMFM_02481 1.37e-271 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NOGEOMFM_02482 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
NOGEOMFM_02483 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NOGEOMFM_02484 4.45e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NOGEOMFM_02485 3.43e-118 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
NOGEOMFM_02486 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NOGEOMFM_02487 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NOGEOMFM_02488 2.1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NOGEOMFM_02489 2.05e-146 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NOGEOMFM_02490 1.77e-261 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NOGEOMFM_02491 2.96e-72 ypuD - - - - - - -
NOGEOMFM_02492 4.99e-127 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NOGEOMFM_02493 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
NOGEOMFM_02494 1.61e-16 - - - S - - - SNARE associated Golgi protein
NOGEOMFM_02496 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NOGEOMFM_02497 2.67e-193 ypuA - - S - - - Secreted protein
NOGEOMFM_02498 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NOGEOMFM_02499 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
NOGEOMFM_02500 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
NOGEOMFM_02501 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
NOGEOMFM_02502 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
NOGEOMFM_02503 5.52e-101 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
NOGEOMFM_02504 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
NOGEOMFM_02505 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
NOGEOMFM_02506 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NOGEOMFM_02507 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NOGEOMFM_02508 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
NOGEOMFM_02509 2.89e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NOGEOMFM_02510 8.04e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NOGEOMFM_02511 2.77e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NOGEOMFM_02512 1.59e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
NOGEOMFM_02513 2.25e-49 - - - S - - - Protein of unknown function (DUF4227)
NOGEOMFM_02514 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NOGEOMFM_02515 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NOGEOMFM_02516 3.73e-44 yqkK - - - - - - -
NOGEOMFM_02517 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NOGEOMFM_02518 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
NOGEOMFM_02519 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
NOGEOMFM_02520 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
NOGEOMFM_02521 3.18e-77 ansR - - K - - - Transcriptional regulator
NOGEOMFM_02522 2.62e-283 yqxK - - L - - - DNA helicase
NOGEOMFM_02523 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
NOGEOMFM_02524 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
NOGEOMFM_02525 2.65e-217 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
NOGEOMFM_02526 1.78e-29 yqkE - - S - - - Protein of unknown function (DUF3886)
NOGEOMFM_02527 7.12e-226 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
NOGEOMFM_02528 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
NOGEOMFM_02529 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
NOGEOMFM_02530 3.37e-250 yqkA - - K - - - GrpB protein
NOGEOMFM_02531 2.25e-71 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
NOGEOMFM_02532 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
NOGEOMFM_02533 9.27e-66 yqiX - - S - - - YolD-like protein
NOGEOMFM_02534 4.7e-303 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NOGEOMFM_02536 7.01e-286 yqjV - - G - - - Major Facilitator Superfamily
NOGEOMFM_02538 1.28e-93 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NOGEOMFM_02539 6.6e-229 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NOGEOMFM_02540 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
NOGEOMFM_02541 3.41e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NOGEOMFM_02542 1.09e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NOGEOMFM_02543 2.56e-185 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NOGEOMFM_02544 0.0 rocB - - E - - - arginine degradation protein
NOGEOMFM_02545 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NOGEOMFM_02546 1.29e-186 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NOGEOMFM_02547 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NOGEOMFM_02548 7.66e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NOGEOMFM_02549 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NOGEOMFM_02550 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NOGEOMFM_02551 2.72e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NOGEOMFM_02552 1.77e-32 yqzJ - - - - - - -
NOGEOMFM_02553 3.36e-184 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NOGEOMFM_02554 8.77e-184 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
NOGEOMFM_02555 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
NOGEOMFM_02556 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NOGEOMFM_02557 7.17e-99 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
NOGEOMFM_02559 2.41e-128 yqjB - - S - - - protein conserved in bacteria
NOGEOMFM_02560 1.55e-224 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
NOGEOMFM_02561 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NOGEOMFM_02562 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NOGEOMFM_02563 6.81e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NOGEOMFM_02564 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
NOGEOMFM_02565 4.06e-212 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NOGEOMFM_02566 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NOGEOMFM_02567 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
NOGEOMFM_02568 3.77e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NOGEOMFM_02569 1.98e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NOGEOMFM_02570 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NOGEOMFM_02571 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NOGEOMFM_02572 3.39e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
NOGEOMFM_02573 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NOGEOMFM_02574 1.18e-196 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
NOGEOMFM_02575 0.0 bkdR - - KT - - - Transcriptional regulator
NOGEOMFM_02576 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
NOGEOMFM_02577 7.23e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NOGEOMFM_02578 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
NOGEOMFM_02579 3.9e-266 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NOGEOMFM_02580 2.01e-267 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
NOGEOMFM_02581 1.19e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
NOGEOMFM_02582 2.59e-277 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NOGEOMFM_02583 7.42e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NOGEOMFM_02584 1.14e-138 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
NOGEOMFM_02585 4.74e-37 - - - - - - - -
NOGEOMFM_02586 2.81e-273 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NOGEOMFM_02588 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NOGEOMFM_02589 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
NOGEOMFM_02590 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NOGEOMFM_02591 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NOGEOMFM_02592 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
NOGEOMFM_02593 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NOGEOMFM_02594 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NOGEOMFM_02595 3.81e-50 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NOGEOMFM_02596 2.05e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NOGEOMFM_02597 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NOGEOMFM_02598 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NOGEOMFM_02599 1.65e-88 yqhY - - S - - - protein conserved in bacteria
NOGEOMFM_02600 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NOGEOMFM_02601 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NOGEOMFM_02602 4.04e-134 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
NOGEOMFM_02603 2.43e-145 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
NOGEOMFM_02604 2.58e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
NOGEOMFM_02605 1.8e-255 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
NOGEOMFM_02606 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
NOGEOMFM_02607 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
NOGEOMFM_02608 5.69e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
NOGEOMFM_02609 3.35e-216 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
NOGEOMFM_02610 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
NOGEOMFM_02611 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NOGEOMFM_02612 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NOGEOMFM_02613 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
NOGEOMFM_02614 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
NOGEOMFM_02615 6.02e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
NOGEOMFM_02616 5.18e-81 yqhP - - - - - - -
NOGEOMFM_02617 3.33e-208 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NOGEOMFM_02618 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NOGEOMFM_02619 9.17e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NOGEOMFM_02620 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
NOGEOMFM_02621 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NOGEOMFM_02622 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NOGEOMFM_02623 1.11e-260 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
NOGEOMFM_02624 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NOGEOMFM_02625 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
NOGEOMFM_02626 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
NOGEOMFM_02627 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
NOGEOMFM_02628 9e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
NOGEOMFM_02629 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
NOGEOMFM_02630 8e-156 yqxM - - - ko:K19433 - ko00000 -
NOGEOMFM_02631 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
NOGEOMFM_02632 3.33e-35 yqzE - - S - - - YqzE-like protein
NOGEOMFM_02633 3.24e-58 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
NOGEOMFM_02634 9.65e-59 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
NOGEOMFM_02635 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
NOGEOMFM_02636 1.05e-88 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
NOGEOMFM_02637 3.09e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
NOGEOMFM_02638 2.14e-219 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
NOGEOMFM_02639 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NOGEOMFM_02641 3.8e-06 - - - S - - - Domain in cystathionine beta-synthase and other proteins.
NOGEOMFM_02642 1.51e-233 yqxL - - P - - - Mg2 transporter protein
NOGEOMFM_02643 2.86e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NOGEOMFM_02644 7.14e-192 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NOGEOMFM_02646 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
NOGEOMFM_02647 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
NOGEOMFM_02648 3.2e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
NOGEOMFM_02649 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
NOGEOMFM_02650 7.34e-66 yqgV - - S - - - Thiamine-binding protein
NOGEOMFM_02651 2.69e-256 yqgU - - - - - - -
NOGEOMFM_02652 3.04e-283 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
NOGEOMFM_02653 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
NOGEOMFM_02654 2.81e-231 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NOGEOMFM_02655 2.19e-44 yqgQ - - S - - - Protein conserved in bacteria
NOGEOMFM_02656 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
NOGEOMFM_02657 3.38e-14 yqgO - - - - - - -
NOGEOMFM_02658 3.8e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NOGEOMFM_02659 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NOGEOMFM_02660 2.81e-257 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
NOGEOMFM_02662 2.81e-67 yqzD - - - - - - -
NOGEOMFM_02663 1.09e-93 yqzC - - S - - - YceG-like family
NOGEOMFM_02664 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NOGEOMFM_02665 2.4e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NOGEOMFM_02666 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
NOGEOMFM_02667 1.43e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NOGEOMFM_02668 2.61e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NOGEOMFM_02669 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
NOGEOMFM_02670 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
NOGEOMFM_02671 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
NOGEOMFM_02672 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
NOGEOMFM_02673 1.58e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
NOGEOMFM_02674 1.64e-62 yqfZ - - M ko:K06417 - ko00000 LysM domain
NOGEOMFM_02675 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NOGEOMFM_02676 2.04e-81 yqfX - - S - - - membrane
NOGEOMFM_02677 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
NOGEOMFM_02678 2.47e-106 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
NOGEOMFM_02679 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NOGEOMFM_02680 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
NOGEOMFM_02681 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NOGEOMFM_02682 5.42e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NOGEOMFM_02683 4.89e-58 yqfQ - - S - - - YqfQ-like protein
NOGEOMFM_02684 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NOGEOMFM_02685 9.26e-270 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NOGEOMFM_02686 2.41e-150 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NOGEOMFM_02687 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NOGEOMFM_02688 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NOGEOMFM_02689 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NOGEOMFM_02690 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
NOGEOMFM_02691 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NOGEOMFM_02692 3.29e-144 ccpN - - K - - - CBS domain
NOGEOMFM_02693 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NOGEOMFM_02694 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NOGEOMFM_02695 5.26e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NOGEOMFM_02696 5.29e-27 - - - S - - - YqzL-like protein
NOGEOMFM_02697 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NOGEOMFM_02698 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NOGEOMFM_02699 1.42e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NOGEOMFM_02700 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NOGEOMFM_02701 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
NOGEOMFM_02703 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
NOGEOMFM_02704 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
NOGEOMFM_02705 2.07e-60 yqfC - - S - - - sporulation protein YqfC
NOGEOMFM_02706 3.13e-79 yqfB - - - - - - -
NOGEOMFM_02707 8.78e-192 yqfA - - S - - - UPF0365 protein
NOGEOMFM_02708 1.32e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
NOGEOMFM_02709 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
NOGEOMFM_02710 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NOGEOMFM_02711 1.4e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
NOGEOMFM_02712 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
NOGEOMFM_02713 6.85e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NOGEOMFM_02714 9.34e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
NOGEOMFM_02715 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NOGEOMFM_02716 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NOGEOMFM_02717 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NOGEOMFM_02718 1.65e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NOGEOMFM_02719 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
NOGEOMFM_02720 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NOGEOMFM_02721 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
NOGEOMFM_02722 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
NOGEOMFM_02723 1.39e-257 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NOGEOMFM_02724 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NOGEOMFM_02725 1.16e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NOGEOMFM_02726 2.36e-22 - - - S - - - YqzM-like protein
NOGEOMFM_02727 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NOGEOMFM_02728 5.39e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NOGEOMFM_02729 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
NOGEOMFM_02730 2.69e-189 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NOGEOMFM_02731 9.8e-179 yqeM - - Q - - - Methyltransferase
NOGEOMFM_02732 9.76e-82 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NOGEOMFM_02733 4.81e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
NOGEOMFM_02734 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NOGEOMFM_02735 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
NOGEOMFM_02736 8.44e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NOGEOMFM_02737 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NOGEOMFM_02738 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
NOGEOMFM_02740 6.41e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
NOGEOMFM_02741 4.44e-172 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
NOGEOMFM_02742 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
NOGEOMFM_02743 1.29e-23 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
NOGEOMFM_02744 3e-169 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
NOGEOMFM_02745 9.38e-171 - - - - - - - -
NOGEOMFM_02746 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
NOGEOMFM_02747 1.1e-72 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NOGEOMFM_02748 0.0 - - - L ko:K06400 - ko00000 Recombinase
NOGEOMFM_02749 9.82e-101 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
NOGEOMFM_02750 7.13e-233 arsB - - P ko:K03325 - ko00000,ko02000 Arsenic resistance protein
NOGEOMFM_02751 2.56e-104 cadI 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NOGEOMFM_02752 1.53e-72 arsR - - K ko:K03892 - ko00000,ko03000 ArsR family transcriptional regulator
NOGEOMFM_02753 2.08e-197 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
NOGEOMFM_02754 1.37e-30 - - - S - - - YtkA-like
NOGEOMFM_02755 9e-62 - - - S - - - PepSY-associated TM region
NOGEOMFM_02756 1.69e-142 - - - S - - - PepSY-associated TM region
NOGEOMFM_02757 3.16e-81 - - - K - - - BetI-type transcriptional repressor, C-terminal
NOGEOMFM_02758 1.78e-175 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
NOGEOMFM_02759 1.77e-61 - - - - - - - -
NOGEOMFM_02760 1.51e-54 - - - S - - - Protein of unknown function (DUF3992)
NOGEOMFM_02761 4.35e-53 - - - S - - - Spore coat protein Z
NOGEOMFM_02762 1.14e-117 - - - S - - - Tetratricopeptide repeat
NOGEOMFM_02765 0.0 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
NOGEOMFM_02766 1.37e-135 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
NOGEOMFM_02768 5.4e-80 - - - - - - - -
NOGEOMFM_02770 9.72e-187 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
NOGEOMFM_02771 8.36e-89 - - - S - - - Bacteriophage holin family
NOGEOMFM_02772 2.45e-213 xepA - - - - - - -
NOGEOMFM_02773 9.34e-33 - - - - - - - -
NOGEOMFM_02774 1.01e-73 xkdW - - S - - - XkdW protein
NOGEOMFM_02775 2.91e-283 - - - - - - - -
NOGEOMFM_02776 3e-54 - - - - - - - -
NOGEOMFM_02777 4.58e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
NOGEOMFM_02778 1.31e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NOGEOMFM_02779 1.14e-91 xkdS - - S - - - Protein of unknown function (DUF2634)
NOGEOMFM_02780 6.68e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
NOGEOMFM_02781 1.02e-231 xkdQ - - G - - - NLP P60 protein
NOGEOMFM_02782 6.56e-156 xkdP - - S - - - Lysin motif
NOGEOMFM_02783 0.0 xkdO - - L - - - Transglycosylase SLT domain
NOGEOMFM_02784 9.14e-88 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
NOGEOMFM_02786 7.03e-98 xkdM - - S - - - Phage tail tube protein
NOGEOMFM_02787 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
NOGEOMFM_02788 1.21e-34 - - - - - - - -
NOGEOMFM_02789 1.48e-98 yqbJ - - - - - - -
NOGEOMFM_02790 1.79e-112 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NOGEOMFM_02791 9.68e-83 yqbH - - S - - - Domain of unknown function (DUF3599)
NOGEOMFM_02792 2.89e-87 - - - S - - - Protein of unknown function (DUF3199)
NOGEOMFM_02793 4.44e-62 - - - S - - - YqbF, hypothetical protein domain
NOGEOMFM_02794 9.21e-216 xkdG - - S - - - Phage capsid family
NOGEOMFM_02795 1.89e-154 yqbD - - L - - - Putative phage serine protease XkdF
NOGEOMFM_02797 5.71e-191 - - - S - - - Phage Mu protein F like protein
NOGEOMFM_02798 0.0 yqbA - - S - - - portal protein
NOGEOMFM_02799 1.35e-315 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
NOGEOMFM_02800 6.34e-146 yqaS - - L - - - DNA packaging
NOGEOMFM_02802 2.33e-116 yrdC - - Q - - - Isochorismatase family
NOGEOMFM_02806 1.11e-65 - - - M - - - ArpU family transcriptional regulator
NOGEOMFM_02807 0.000203 - - - S - - - Bacillus cereus group antimicrobial protein
NOGEOMFM_02808 3.42e-41 yqaO - - S - - - Phage-like element PBSX protein XtrA
NOGEOMFM_02809 2.38e-89 rusA - - L - - - Endodeoxyribonuclease RusA
NOGEOMFM_02811 6.14e-208 yqaM - - L - - - IstB-like ATP binding protein
NOGEOMFM_02812 1.3e-156 yqaL - - L - - - DnaD domain protein
NOGEOMFM_02813 2.98e-187 recT - - L ko:K07455 - ko00000,ko03400 RecT family
NOGEOMFM_02814 1.95e-221 yqaJ - - L - - - YqaJ-like viral recombinase domain
NOGEOMFM_02818 3.5e-132 - - - - - - - -
NOGEOMFM_02820 6.26e-24 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
NOGEOMFM_02821 1.88e-42 - - - K - - - sequence-specific DNA binding
NOGEOMFM_02823 8.73e-132 yqaC - - F - - - adenylate kinase activity
NOGEOMFM_02824 7.83e-123 xkdA - - E - - - IrrE N-terminal-like domain
NOGEOMFM_02825 4.46e-79 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NOGEOMFM_02826 7.32e-306 yrkQ - - T - - - Histidine kinase
NOGEOMFM_02827 1.24e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
NOGEOMFM_02828 2.16e-282 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
NOGEOMFM_02829 6.33e-133 yrkN - - K - - - Acetyltransferase (GNAT) family
NOGEOMFM_02830 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
NOGEOMFM_02831 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
NOGEOMFM_02832 1.9e-149 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
NOGEOMFM_02833 3.2e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
NOGEOMFM_02834 2.07e-263 yrkH - - P - - - Rhodanese Homology Domain
NOGEOMFM_02835 2.28e-126 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
NOGEOMFM_02836 7.44e-86 yrkE - - O - - - DsrE/DsrF/DrsH-like family
NOGEOMFM_02837 4.38e-52 yrkD - - S - - - protein conserved in bacteria
NOGEOMFM_02838 1.82e-137 yrkC - - G - - - Cupin domain
NOGEOMFM_02839 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
NOGEOMFM_02840 7.59e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
NOGEOMFM_02841 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
NOGEOMFM_02842 1.02e-297 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NOGEOMFM_02843 2.45e-23 - - - S - - - YrzO-like protein
NOGEOMFM_02844 2.84e-215 yrdR - - EG - - - EamA-like transporter family
NOGEOMFM_02845 1.64e-202 - - - K - - - Transcriptional regulator
NOGEOMFM_02846 7.41e-255 trkA - - P ko:K07222 - ko00000 Oxidoreductase
NOGEOMFM_02847 2e-211 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
NOGEOMFM_02848 1.44e-86 yodA - - S - - - tautomerase
NOGEOMFM_02849 6.6e-201 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
NOGEOMFM_02850 5.01e-41 - - - C - - - COG2041 Sulfite oxidase and related enzymes
NOGEOMFM_02851 1.43e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NOGEOMFM_02852 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
NOGEOMFM_02853 9.34e-176 azlC - - E - - - AzlC protein
NOGEOMFM_02854 1.18e-103 bkdR - - K - - - helix_turn_helix ASNC type
NOGEOMFM_02855 5.04e-22 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
NOGEOMFM_02856 8.91e-289 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NOGEOMFM_02857 7.38e-131 yrdC - - Q - - - Isochorismatase family
NOGEOMFM_02858 2.99e-71 - - - S - - - Protein of unknown function (DUF2568)
NOGEOMFM_02859 1.17e-117 yrdA - - S - - - DinB family
NOGEOMFM_02860 5.77e-210 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
NOGEOMFM_02861 5.15e-247 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NOGEOMFM_02862 1.39e-187 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NOGEOMFM_02863 4.62e-160 yrpD - - S - - - Domain of unknown function, YrpD
NOGEOMFM_02864 6.71e-128 - - - K ko:K05799 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
NOGEOMFM_02866 4.11e-268 - - - P - - - Major Facilitator Superfamily
NOGEOMFM_02867 6.21e-148 - - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NOGEOMFM_02868 1.02e-192 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
NOGEOMFM_02869 4.98e-172 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG3959 Transketolase, N-terminal subunit
NOGEOMFM_02870 3.1e-126 - - - S - - - Flavin reductase like domain
NOGEOMFM_02871 1.12e-156 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
NOGEOMFM_02872 1.62e-63 - - - S - - - YjbR
NOGEOMFM_02873 7.31e-167 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NOGEOMFM_02874 3.99e-118 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NOGEOMFM_02875 5.96e-240 yrpG - - C - - - Aldo/keto reductase family
NOGEOMFM_02876 2.16e-285 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NOGEOMFM_02877 2.97e-210 yraN - - K - - - Transcriptional regulator
NOGEOMFM_02878 1.71e-262 yraM - - S - - - PrpF protein
NOGEOMFM_02879 9.5e-201 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NOGEOMFM_02880 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NOGEOMFM_02881 2.33e-194 - - - S - - - Alpha beta hydrolase
NOGEOMFM_02882 6.61e-80 - - - T - - - sh3 domain protein
NOGEOMFM_02883 1.69e-80 - - - T - - - sh3 domain protein
NOGEOMFM_02884 5.45e-86 - - - E - - - Glyoxalase-like domain
NOGEOMFM_02885 1.2e-49 yraG - - - ko:K06440 - ko00000 -
NOGEOMFM_02886 7.91e-83 yraF - - M - - - Spore coat protein
NOGEOMFM_02887 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NOGEOMFM_02888 6.11e-36 yraE - - - ko:K06440 - ko00000 -
NOGEOMFM_02889 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
NOGEOMFM_02890 3.7e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
NOGEOMFM_02891 3.95e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
NOGEOMFM_02892 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
NOGEOMFM_02893 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NOGEOMFM_02894 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NOGEOMFM_02895 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NOGEOMFM_02896 8.91e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
NOGEOMFM_02897 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
NOGEOMFM_02898 0.0 levR - - K - - - PTS system fructose IIA component
NOGEOMFM_02899 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
NOGEOMFM_02900 5.63e-137 yrhP - - E - - - LysE type translocator
NOGEOMFM_02901 1.98e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
NOGEOMFM_02902 8.2e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NOGEOMFM_02903 7.4e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
NOGEOMFM_02904 0.0 oatA - - I - - - Acyltransferase family
NOGEOMFM_02905 1.15e-70 oatA - - I - - - Acyltransferase family
NOGEOMFM_02906 1.55e-61 yrhK - - S - - - YrhK-like protein
NOGEOMFM_02907 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
NOGEOMFM_02908 9.22e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
NOGEOMFM_02909 7.42e-125 yrhH - - Q - - - methyltransferase
NOGEOMFM_02910 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
NOGEOMFM_02912 1.38e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
NOGEOMFM_02914 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
NOGEOMFM_02915 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
NOGEOMFM_02916 4.26e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
NOGEOMFM_02917 6.93e-49 yrhC - - S - - - YrhC-like protein
NOGEOMFM_02918 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NOGEOMFM_02919 7.04e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
NOGEOMFM_02920 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NOGEOMFM_02921 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
NOGEOMFM_02922 8.52e-37 yrzA - - S - - - Protein of unknown function (DUF2536)
NOGEOMFM_02923 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
NOGEOMFM_02924 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
NOGEOMFM_02925 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NOGEOMFM_02926 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NOGEOMFM_02927 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
NOGEOMFM_02928 7.67e-223 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
NOGEOMFM_02929 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
NOGEOMFM_02930 7.19e-240 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NOGEOMFM_02931 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
NOGEOMFM_02932 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NOGEOMFM_02933 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
NOGEOMFM_02934 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NOGEOMFM_02935 8.81e-242 yrrI - - S - - - AI-2E family transporter
NOGEOMFM_02936 1.89e-169 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NOGEOMFM_02937 1.28e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NOGEOMFM_02938 6.53e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NOGEOMFM_02939 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NOGEOMFM_02940 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
NOGEOMFM_02941 8.4e-42 yrzR - - - - - - -
NOGEOMFM_02942 3.39e-106 yrrD - - S - - - protein conserved in bacteria
NOGEOMFM_02943 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NOGEOMFM_02944 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
NOGEOMFM_02945 3.4e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NOGEOMFM_02946 1.09e-271 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NOGEOMFM_02947 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_02948 2.44e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NOGEOMFM_02949 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NOGEOMFM_02950 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NOGEOMFM_02951 1.27e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NOGEOMFM_02953 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
NOGEOMFM_02954 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NOGEOMFM_02955 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NOGEOMFM_02956 8.47e-117 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NOGEOMFM_02957 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NOGEOMFM_02958 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
NOGEOMFM_02959 3.1e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
NOGEOMFM_02960 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NOGEOMFM_02961 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
NOGEOMFM_02962 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NOGEOMFM_02963 5.83e-143 yrbG - - S - - - membrane
NOGEOMFM_02964 2.95e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
NOGEOMFM_02965 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
NOGEOMFM_02966 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NOGEOMFM_02967 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NOGEOMFM_02968 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
NOGEOMFM_02969 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NOGEOMFM_02970 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NOGEOMFM_02971 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
NOGEOMFM_02972 0.0 csbX - - EGP - - - the major facilitator superfamily
NOGEOMFM_02973 2.65e-246 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
NOGEOMFM_02974 2.32e-152 yrzF - - T - - - serine threonine protein kinase
NOGEOMFM_02976 2.55e-67 - - - S - - - Family of unknown function (DUF5412)
NOGEOMFM_02977 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
NOGEOMFM_02978 8.63e-165 yebC - - K - - - transcriptional regulatory protein
NOGEOMFM_02979 2.08e-69 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NOGEOMFM_02980 4.02e-216 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
NOGEOMFM_02981 7.94e-273 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NOGEOMFM_02982 5.07e-202 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
NOGEOMFM_02983 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
NOGEOMFM_02984 3.35e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NOGEOMFM_02985 5.86e-122 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
NOGEOMFM_02986 4.99e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
NOGEOMFM_02987 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
NOGEOMFM_02988 1.6e-307 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NOGEOMFM_02989 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
NOGEOMFM_02990 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NOGEOMFM_02991 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
NOGEOMFM_02992 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NOGEOMFM_02993 1.25e-206 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
NOGEOMFM_02994 1.5e-186 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NOGEOMFM_02995 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
NOGEOMFM_02996 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NOGEOMFM_02997 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
NOGEOMFM_02998 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NOGEOMFM_02999 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
NOGEOMFM_03000 1.97e-161 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
NOGEOMFM_03001 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
NOGEOMFM_03002 3.08e-206 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
NOGEOMFM_03003 1.81e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NOGEOMFM_03004 7.42e-314 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NOGEOMFM_03005 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NOGEOMFM_03006 1.53e-35 - - - - - - - -
NOGEOMFM_03007 9.73e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NOGEOMFM_03008 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
NOGEOMFM_03009 3.53e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
NOGEOMFM_03010 3.04e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
NOGEOMFM_03011 2.49e-184 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NOGEOMFM_03012 2.19e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NOGEOMFM_03013 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
NOGEOMFM_03014 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NOGEOMFM_03015 4.77e-116 ysxD - - - - - - -
NOGEOMFM_03016 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NOGEOMFM_03017 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NOGEOMFM_03018 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
NOGEOMFM_03019 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NOGEOMFM_03020 4.21e-285 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NOGEOMFM_03021 2.73e-240 ysoA - - H - - - Tetratricopeptide repeat
NOGEOMFM_03022 5.35e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NOGEOMFM_03023 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NOGEOMFM_03024 1.75e-254 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NOGEOMFM_03025 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NOGEOMFM_03026 3.91e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NOGEOMFM_03027 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NOGEOMFM_03028 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
NOGEOMFM_03030 1.71e-100 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
NOGEOMFM_03031 9.59e-48 ysnF - - S - - - protein conserved in bacteria
NOGEOMFM_03033 2.34e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
NOGEOMFM_03034 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NOGEOMFM_03035 2.04e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NOGEOMFM_03036 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
NOGEOMFM_03037 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NOGEOMFM_03038 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
NOGEOMFM_03039 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_03040 1.79e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
NOGEOMFM_03041 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NOGEOMFM_03042 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
NOGEOMFM_03043 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
NOGEOMFM_03044 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
NOGEOMFM_03045 3.96e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NOGEOMFM_03046 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NOGEOMFM_03047 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NOGEOMFM_03048 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
NOGEOMFM_03050 1.23e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
NOGEOMFM_03051 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
NOGEOMFM_03052 2.2e-176 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
NOGEOMFM_03053 1.21e-130 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_03054 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NOGEOMFM_03055 7.59e-89 yshE - - S ko:K08989 - ko00000 membrane
NOGEOMFM_03056 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NOGEOMFM_03057 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
NOGEOMFM_03058 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
NOGEOMFM_03059 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NOGEOMFM_03060 2.96e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NOGEOMFM_03061 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NOGEOMFM_03062 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NOGEOMFM_03063 2.57e-170 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NOGEOMFM_03064 4.37e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
NOGEOMFM_03065 1.92e-264 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
NOGEOMFM_03066 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
NOGEOMFM_03067 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
NOGEOMFM_03068 2.94e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
NOGEOMFM_03069 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
NOGEOMFM_03070 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
NOGEOMFM_03071 6.34e-192 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
NOGEOMFM_03072 6.77e-219 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
NOGEOMFM_03073 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
NOGEOMFM_03074 3.72e-282 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NOGEOMFM_03075 1.74e-186 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
NOGEOMFM_03076 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NOGEOMFM_03077 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
NOGEOMFM_03078 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
NOGEOMFM_03079 4.04e-241 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NOGEOMFM_03080 4.35e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
NOGEOMFM_03081 2.29e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
NOGEOMFM_03082 1.27e-59 ysdA - - S - - - Membrane
NOGEOMFM_03083 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NOGEOMFM_03084 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NOGEOMFM_03085 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NOGEOMFM_03087 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NOGEOMFM_03088 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NOGEOMFM_03089 1.96e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
NOGEOMFM_03090 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NOGEOMFM_03091 1.2e-190 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
NOGEOMFM_03092 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NOGEOMFM_03093 5.98e-206 ytxC - - S - - - YtxC-like family
NOGEOMFM_03094 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
NOGEOMFM_03095 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NOGEOMFM_03096 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
NOGEOMFM_03097 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NOGEOMFM_03098 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NOGEOMFM_03099 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NOGEOMFM_03100 9.85e-88 ytcD - - K - - - Transcriptional regulator
NOGEOMFM_03101 1.12e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
NOGEOMFM_03102 4.54e-205 ytbE - - S - - - reductase
NOGEOMFM_03103 2.82e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NOGEOMFM_03104 5.63e-137 ytaF - - P - - - Probably functions as a manganese efflux pump
NOGEOMFM_03105 3.88e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NOGEOMFM_03106 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NOGEOMFM_03107 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
NOGEOMFM_03108 3.27e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NOGEOMFM_03109 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
NOGEOMFM_03110 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
NOGEOMFM_03111 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
NOGEOMFM_03112 9.38e-95 ytwI - - S - - - membrane
NOGEOMFM_03113 6.42e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
NOGEOMFM_03114 4.68e-82 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
NOGEOMFM_03115 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NOGEOMFM_03116 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NOGEOMFM_03117 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NOGEOMFM_03118 2.17e-208 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NOGEOMFM_03119 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NOGEOMFM_03120 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NOGEOMFM_03121 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
NOGEOMFM_03122 5.98e-111 ytrI - - - - - - -
NOGEOMFM_03123 1.15e-39 - - - - - - - -
NOGEOMFM_03124 1.02e-229 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
NOGEOMFM_03125 2.15e-63 ytpI - - S - - - YtpI-like protein
NOGEOMFM_03126 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
NOGEOMFM_03127 6.14e-204 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
NOGEOMFM_03128 1.41e-304 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
NOGEOMFM_03129 9.41e-164 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
NOGEOMFM_03130 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NOGEOMFM_03131 1.24e-61 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
NOGEOMFM_03132 6.9e-234 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NOGEOMFM_03133 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
NOGEOMFM_03134 2.64e-152 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NOGEOMFM_03135 6.75e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NOGEOMFM_03136 2.71e-192 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NOGEOMFM_03137 2.15e-193 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NOGEOMFM_03138 2.31e-127 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
NOGEOMFM_03139 4.99e-223 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
NOGEOMFM_03140 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
NOGEOMFM_03141 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NOGEOMFM_03143 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NOGEOMFM_03144 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NOGEOMFM_03145 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
NOGEOMFM_03146 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NOGEOMFM_03147 6.26e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
NOGEOMFM_03148 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NOGEOMFM_03149 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
NOGEOMFM_03150 5.03e-150 ytfI - - S - - - Protein of unknown function (DUF2953)
NOGEOMFM_03151 2.36e-111 yteJ - - S - - - RDD family
NOGEOMFM_03152 5.87e-231 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
NOGEOMFM_03153 4.85e-189 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NOGEOMFM_03154 0.0 ytcJ - - S - - - amidohydrolase
NOGEOMFM_03155 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NOGEOMFM_03156 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
NOGEOMFM_03157 6.26e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NOGEOMFM_03158 1.22e-269 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
NOGEOMFM_03159 8.23e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NOGEOMFM_03160 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NOGEOMFM_03161 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NOGEOMFM_03162 1.2e-141 yttP - - K - - - Transcriptional regulator
NOGEOMFM_03163 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
NOGEOMFM_03164 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
NOGEOMFM_03165 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NOGEOMFM_03167 1.85e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NOGEOMFM_03168 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NOGEOMFM_03169 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NOGEOMFM_03170 6.16e-152 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
NOGEOMFM_03171 2.65e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
NOGEOMFM_03172 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
NOGEOMFM_03173 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
NOGEOMFM_03174 4.86e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NOGEOMFM_03175 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NOGEOMFM_03176 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
NOGEOMFM_03177 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
NOGEOMFM_03178 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NOGEOMFM_03179 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NOGEOMFM_03180 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NOGEOMFM_03181 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NOGEOMFM_03182 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
NOGEOMFM_03183 3.17e-75 ytpP - - CO - - - Thioredoxin
NOGEOMFM_03184 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
NOGEOMFM_03185 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
NOGEOMFM_03186 1.17e-67 ytzB - - S - - - small secreted protein
NOGEOMFM_03187 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
NOGEOMFM_03188 5.09e-192 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
NOGEOMFM_03189 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NOGEOMFM_03190 9.51e-61 ytzH - - S - - - YtzH-like protein
NOGEOMFM_03191 3.02e-192 ytmP - - M - - - Phosphotransferase
NOGEOMFM_03192 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NOGEOMFM_03193 9.05e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
NOGEOMFM_03194 4.04e-211 ytlQ - - - - - - -
NOGEOMFM_03195 4.29e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NOGEOMFM_03196 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NOGEOMFM_03197 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
NOGEOMFM_03198 2.35e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
NOGEOMFM_03199 3.51e-255 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
NOGEOMFM_03200 5.66e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NOGEOMFM_03201 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
NOGEOMFM_03202 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NOGEOMFM_03203 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NOGEOMFM_03204 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
NOGEOMFM_03205 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
NOGEOMFM_03206 2.14e-36 yteV - - S - - - Sporulation protein Cse60
NOGEOMFM_03207 1.55e-149 yteU - - S - - - Integral membrane protein
NOGEOMFM_03208 0.0 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
NOGEOMFM_03209 4.78e-94 yteS - - G - - - transport
NOGEOMFM_03210 1.88e-275 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NOGEOMFM_03211 2.27e-221 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
NOGEOMFM_03212 0.0 ytdP - - K - - - Transcriptional regulator
NOGEOMFM_03213 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
NOGEOMFM_03214 1.02e-191 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
NOGEOMFM_03215 8.64e-176 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
NOGEOMFM_03216 1.03e-284 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NOGEOMFM_03217 2.64e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NOGEOMFM_03218 9.36e-160 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NOGEOMFM_03219 6.91e-280 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NOGEOMFM_03220 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NOGEOMFM_03221 2.73e-180 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NOGEOMFM_03222 1.95e-220 - - - S - - - Acetyl xylan esterase (AXE1)
NOGEOMFM_03223 1.53e-242 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_03224 7.08e-310 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
NOGEOMFM_03225 5.54e-213 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NOGEOMFM_03226 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NOGEOMFM_03227 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
NOGEOMFM_03228 7.08e-68 ytwF - - P - - - Sulfurtransferase
NOGEOMFM_03229 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NOGEOMFM_03230 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
NOGEOMFM_03231 5.43e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NOGEOMFM_03232 1.21e-268 yttB - - EGP - - - Major facilitator superfamily
NOGEOMFM_03233 5.75e-78 yttA - - S - - - Pfam Transposase IS66
NOGEOMFM_03234 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
NOGEOMFM_03235 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_03236 4.53e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
NOGEOMFM_03237 2.07e-166 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NOGEOMFM_03238 6.91e-297 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NOGEOMFM_03239 1.02e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_03240 1.63e-163 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
NOGEOMFM_03241 5.22e-187 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
NOGEOMFM_03242 1.4e-205 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_03243 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
NOGEOMFM_03245 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
NOGEOMFM_03246 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
NOGEOMFM_03247 1.59e-135 ytqB - - J - - - Putative rRNA methylase
NOGEOMFM_03248 2.78e-275 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
NOGEOMFM_03249 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
NOGEOMFM_03250 5.88e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NOGEOMFM_03251 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NOGEOMFM_03252 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NOGEOMFM_03253 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NOGEOMFM_03254 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NOGEOMFM_03255 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
NOGEOMFM_03256 5.48e-190 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NOGEOMFM_03257 6.26e-239 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NOGEOMFM_03258 6.12e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NOGEOMFM_03259 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NOGEOMFM_03260 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
NOGEOMFM_03261 6.47e-81 ytkC - - S - - - Bacteriophage holin family
NOGEOMFM_03262 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NOGEOMFM_03264 6.79e-95 ytkA - - S - - - YtkA-like
NOGEOMFM_03265 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NOGEOMFM_03266 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NOGEOMFM_03267 1.44e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NOGEOMFM_03268 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NOGEOMFM_03269 6.96e-240 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NOGEOMFM_03270 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
NOGEOMFM_03271 2.65e-191 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NOGEOMFM_03272 1.01e-293 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NOGEOMFM_03273 9.74e-176 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NOGEOMFM_03274 3.77e-217 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NOGEOMFM_03275 2.88e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NOGEOMFM_03276 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NOGEOMFM_03277 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NOGEOMFM_03278 1.29e-192 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NOGEOMFM_03279 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NOGEOMFM_03280 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NOGEOMFM_03281 7.13e-168 yteA - - T - - - COG1734 DnaK suppressor protein
NOGEOMFM_03282 2.82e-195 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
NOGEOMFM_03283 1.6e-307 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NOGEOMFM_03284 1.23e-227 ytcB - - M - - - NAD-dependent epimerase dehydratase
NOGEOMFM_03285 5.88e-297 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
NOGEOMFM_03287 2.82e-262 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
NOGEOMFM_03288 1.01e-275 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
NOGEOMFM_03289 1.29e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
NOGEOMFM_03290 1.9e-99 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
NOGEOMFM_03291 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NOGEOMFM_03292 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
NOGEOMFM_03293 5.28e-238 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
NOGEOMFM_03294 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NOGEOMFM_03295 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NOGEOMFM_03317 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
NOGEOMFM_03318 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
NOGEOMFM_03319 1.2e-122 - - - M - - - FR47-like protein
NOGEOMFM_03320 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
NOGEOMFM_03321 4.82e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
NOGEOMFM_03322 1.95e-109 yuaE - - S - - - DinB superfamily
NOGEOMFM_03323 8.58e-139 yuaD - - - - - - -
NOGEOMFM_03324 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
NOGEOMFM_03325 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NOGEOMFM_03326 3.53e-123 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
NOGEOMFM_03327 5.83e-118 yuaB - - - - - - -
NOGEOMFM_03328 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
NOGEOMFM_03329 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
NOGEOMFM_03330 3.31e-52 yubF - - S - - - yiaA/B two helix domain
NOGEOMFM_03331 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NOGEOMFM_03332 0.0 yubD - - P - - - Major Facilitator Superfamily
NOGEOMFM_03333 1.61e-112 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
NOGEOMFM_03335 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NOGEOMFM_03336 7.34e-254 yubA - - S - - - transporter activity
NOGEOMFM_03337 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NOGEOMFM_03338 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
NOGEOMFM_03339 2.02e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
NOGEOMFM_03340 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NOGEOMFM_03341 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NOGEOMFM_03342 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
NOGEOMFM_03343 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NOGEOMFM_03344 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NOGEOMFM_03345 1.31e-294 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NOGEOMFM_03346 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NOGEOMFM_03347 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
NOGEOMFM_03348 1.44e-47 - - - - - - - -
NOGEOMFM_03349 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
NOGEOMFM_03350 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NOGEOMFM_03351 1.03e-299 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
NOGEOMFM_03352 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
NOGEOMFM_03353 1.58e-50 - - - - - - - -
NOGEOMFM_03354 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
NOGEOMFM_03355 1.45e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
NOGEOMFM_03356 9.97e-94 yugN - - S - - - YugN-like family
NOGEOMFM_03358 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NOGEOMFM_03359 5.34e-289 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
NOGEOMFM_03360 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
NOGEOMFM_03361 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
NOGEOMFM_03362 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
NOGEOMFM_03363 3.14e-254 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
NOGEOMFM_03364 6.74e-112 alaR - - K - - - Transcriptional regulator
NOGEOMFM_03365 9.89e-201 yugF - - I - - - Hydrolase
NOGEOMFM_03366 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
NOGEOMFM_03367 4.53e-284 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NOGEOMFM_03368 1.06e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NOGEOMFM_03369 1.44e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
NOGEOMFM_03370 8.49e-150 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
NOGEOMFM_03372 8.9e-242 yuxJ - - EGP - - - Major facilitator superfamily
NOGEOMFM_03373 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
NOGEOMFM_03374 3.31e-98 yuxK - - S - - - protein conserved in bacteria
NOGEOMFM_03375 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
NOGEOMFM_03376 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
NOGEOMFM_03377 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
NOGEOMFM_03378 1.84e-246 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
NOGEOMFM_03379 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_03380 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NOGEOMFM_03381 6.97e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NOGEOMFM_03382 7.99e-309 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
NOGEOMFM_03383 1.73e-22 - - - - - - - -
NOGEOMFM_03384 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NOGEOMFM_03385 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NOGEOMFM_03386 1.72e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NOGEOMFM_03387 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NOGEOMFM_03388 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NOGEOMFM_03389 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NOGEOMFM_03390 9.92e-78 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
NOGEOMFM_03391 2.24e-82 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
NOGEOMFM_03392 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NOGEOMFM_03393 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NOGEOMFM_03395 8.19e-169 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
NOGEOMFM_03396 6.29e-10 - - - S - - - DegQ (SacQ) family
NOGEOMFM_03397 8.73e-09 yuzC - - - - - - -
NOGEOMFM_03398 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
NOGEOMFM_03399 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NOGEOMFM_03400 7.71e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
NOGEOMFM_03401 3.64e-86 - - - S - - - Protein of unknown function (DUF1694)
NOGEOMFM_03402 1.63e-52 yueH - - S - - - YueH-like protein
NOGEOMFM_03403 2.05e-42 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
NOGEOMFM_03404 5.5e-244 yueF - - S - - - transporter activity
NOGEOMFM_03405 7.71e-91 - - - S - - - Protein of unknown function (DUF2283)
NOGEOMFM_03406 8.4e-33 - - - S - - - Protein of unknown function (DUF2642)
NOGEOMFM_03407 1.91e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
NOGEOMFM_03408 2.04e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NOGEOMFM_03409 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
NOGEOMFM_03410 0.0 yueB - - S - - - type VII secretion protein EsaA
NOGEOMFM_03411 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NOGEOMFM_03412 3.93e-270 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
NOGEOMFM_03413 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
NOGEOMFM_03414 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
NOGEOMFM_03415 8.49e-292 yukF - - QT - - - Transcriptional regulator
NOGEOMFM_03416 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
NOGEOMFM_03417 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
NOGEOMFM_03418 4.08e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
NOGEOMFM_03419 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NOGEOMFM_03420 4.47e-228 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
NOGEOMFM_03421 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
NOGEOMFM_03422 7.34e-291 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
NOGEOMFM_03423 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NOGEOMFM_03424 8.58e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
NOGEOMFM_03425 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
NOGEOMFM_03426 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
NOGEOMFM_03427 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
NOGEOMFM_03428 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NOGEOMFM_03429 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
NOGEOMFM_03430 3.14e-149 yuiC - - S - - - protein conserved in bacteria
NOGEOMFM_03431 1.14e-45 yuiB - - S - - - Putative membrane protein
NOGEOMFM_03432 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NOGEOMFM_03433 1.16e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
NOGEOMFM_03435 4.51e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NOGEOMFM_03436 8.15e-149 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
NOGEOMFM_03437 3.98e-115 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NOGEOMFM_03438 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
NOGEOMFM_03439 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NOGEOMFM_03440 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NOGEOMFM_03441 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
NOGEOMFM_03442 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NOGEOMFM_03443 5.44e-74 yuzD - - S - - - protein conserved in bacteria
NOGEOMFM_03444 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
NOGEOMFM_03445 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
NOGEOMFM_03446 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NOGEOMFM_03447 2.4e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NOGEOMFM_03448 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NOGEOMFM_03449 1.55e-253 yutH - - S - - - Spore coat protein
NOGEOMFM_03450 3.21e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
NOGEOMFM_03451 2.49e-181 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NOGEOMFM_03452 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
NOGEOMFM_03453 3.2e-63 yutD - - S - - - protein conserved in bacteria
NOGEOMFM_03454 5.47e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NOGEOMFM_03455 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NOGEOMFM_03456 3.11e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
NOGEOMFM_03457 2.46e-171 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
NOGEOMFM_03458 3.41e-65 yunC - - S - - - Domain of unknown function (DUF1805)
NOGEOMFM_03459 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NOGEOMFM_03460 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
NOGEOMFM_03461 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
NOGEOMFM_03462 1.07e-79 yunG - - - - - - -
NOGEOMFM_03463 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NOGEOMFM_03464 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
NOGEOMFM_03465 2.82e-298 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
NOGEOMFM_03466 1.24e-280 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
NOGEOMFM_03467 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NOGEOMFM_03468 2.09e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NOGEOMFM_03469 2.42e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NOGEOMFM_03470 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NOGEOMFM_03471 4.85e-194 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NOGEOMFM_03472 6.18e-143 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
NOGEOMFM_03473 3.56e-234 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NOGEOMFM_03474 8.16e-304 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NOGEOMFM_03475 1.64e-301 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NOGEOMFM_03476 1.8e-215 bsn - - L - - - Ribonuclease
NOGEOMFM_03477 2.42e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NOGEOMFM_03478 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
NOGEOMFM_03479 5.54e-208 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
NOGEOMFM_03480 4.58e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
NOGEOMFM_03481 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
NOGEOMFM_03482 1.66e-306 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
NOGEOMFM_03483 5.27e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NOGEOMFM_03484 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
NOGEOMFM_03485 2.52e-262 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
NOGEOMFM_03487 3.35e-56 - - - - - - - -
NOGEOMFM_03488 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
NOGEOMFM_03489 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
NOGEOMFM_03490 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NOGEOMFM_03491 1.23e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
NOGEOMFM_03492 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NOGEOMFM_03493 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NOGEOMFM_03494 1.01e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
NOGEOMFM_03495 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
NOGEOMFM_03496 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NOGEOMFM_03497 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
NOGEOMFM_03498 2e-73 yusE - - CO - - - Thioredoxin
NOGEOMFM_03499 7.62e-97 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
NOGEOMFM_03500 7.34e-54 yusG - - S - - - Protein of unknown function (DUF2553)
NOGEOMFM_03501 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NOGEOMFM_03502 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
NOGEOMFM_03503 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
NOGEOMFM_03504 1.34e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
NOGEOMFM_03505 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
NOGEOMFM_03506 1.11e-13 - - - S - - - YuzL-like protein
NOGEOMFM_03507 6.98e-211 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
NOGEOMFM_03508 2.23e-54 - - - - - - - -
NOGEOMFM_03509 8.66e-70 yusN - - M - - - Coat F domain
NOGEOMFM_03510 4.47e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
NOGEOMFM_03511 0.0 yusP - - P - - - Major facilitator superfamily
NOGEOMFM_03512 2.93e-85 yusQ - - S - - - Tautomerase enzyme
NOGEOMFM_03513 8.6e-139 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NOGEOMFM_03514 8.42e-204 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
NOGEOMFM_03515 3.66e-64 yusU - - S - - - Protein of unknown function (DUF2573)
NOGEOMFM_03516 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NOGEOMFM_03517 2.86e-87 - - - S - - - YusW-like protein
NOGEOMFM_03518 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
NOGEOMFM_03519 1.1e-196 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NOGEOMFM_03520 8.76e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
NOGEOMFM_03521 5.56e-305 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NOGEOMFM_03522 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NOGEOMFM_03523 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NOGEOMFM_03524 3.06e-204 yuxN - - K - - - Transcriptional regulator
NOGEOMFM_03525 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NOGEOMFM_03526 4.48e-34 - - - S - - - Protein of unknown function (DUF3970)
NOGEOMFM_03527 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
NOGEOMFM_03528 2.9e-253 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NOGEOMFM_03529 3.48e-249 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
NOGEOMFM_03530 9.39e-141 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NOGEOMFM_03531 2.74e-244 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NOGEOMFM_03532 7.65e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
NOGEOMFM_03533 2.48e-166 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
NOGEOMFM_03534 2.44e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NOGEOMFM_03535 1.51e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
NOGEOMFM_03536 9.24e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NOGEOMFM_03537 4.56e-130 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
NOGEOMFM_03538 2.47e-307 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NOGEOMFM_03539 2.7e-236 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NOGEOMFM_03540 1.21e-217 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NOGEOMFM_03541 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NOGEOMFM_03542 3.79e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
NOGEOMFM_03543 0.0 yvrG - - T - - - Histidine kinase
NOGEOMFM_03544 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NOGEOMFM_03545 5.07e-32 - - - - - - - -
NOGEOMFM_03546 5.77e-127 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
NOGEOMFM_03547 4.92e-26 - - - S - - - YvrJ protein family
NOGEOMFM_03548 1.86e-291 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
NOGEOMFM_03549 8.13e-85 yvrL - - S - - - Regulatory protein YrvL
NOGEOMFM_03550 2.21e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
NOGEOMFM_03551 3.82e-158 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_03552 3.61e-231 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
NOGEOMFM_03553 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NOGEOMFM_03554 3.76e-223 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NOGEOMFM_03555 2e-235 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NOGEOMFM_03556 4.45e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NOGEOMFM_03558 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
NOGEOMFM_03559 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
NOGEOMFM_03560 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
NOGEOMFM_03561 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
NOGEOMFM_03562 4.91e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
NOGEOMFM_03563 2.11e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
NOGEOMFM_03564 1.95e-150 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
NOGEOMFM_03565 6.19e-201 yvgN - - S - - - reductase
NOGEOMFM_03566 7.97e-113 yvgO - - - - - - -
NOGEOMFM_03567 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
NOGEOMFM_03568 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NOGEOMFM_03569 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NOGEOMFM_03570 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NOGEOMFM_03572 2.34e-139 yvgT - - S - - - membrane
NOGEOMFM_03573 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
NOGEOMFM_03574 3.45e-137 bdbD - - O - - - Thioredoxin
NOGEOMFM_03575 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
NOGEOMFM_03576 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NOGEOMFM_03577 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
NOGEOMFM_03578 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
NOGEOMFM_03579 1.4e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
NOGEOMFM_03580 2.08e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NOGEOMFM_03581 0.0 - - - S - - - Fusaric acid resistance protein-like
NOGEOMFM_03582 2.02e-97 yvaD - - S - - - Family of unknown function (DUF5360)
NOGEOMFM_03583 3.52e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
NOGEOMFM_03584 1.51e-123 - - - K - - - Bacterial regulatory proteins, tetR family
NOGEOMFM_03585 9.32e-181 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NOGEOMFM_03587 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NOGEOMFM_03588 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NOGEOMFM_03589 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
NOGEOMFM_03590 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
NOGEOMFM_03591 5.5e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
NOGEOMFM_03592 3.44e-48 yvzC - - K - - - transcriptional
NOGEOMFM_03593 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
NOGEOMFM_03594 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
NOGEOMFM_03595 3.85e-72 yvaP - - K - - - transcriptional
NOGEOMFM_03596 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
NOGEOMFM_03597 1.31e-143 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NOGEOMFM_03598 3.37e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NOGEOMFM_03599 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NOGEOMFM_03600 8.57e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NOGEOMFM_03601 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NOGEOMFM_03602 1.37e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NOGEOMFM_03603 4.11e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NOGEOMFM_03604 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
NOGEOMFM_03605 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NOGEOMFM_03606 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
NOGEOMFM_03607 7.95e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
NOGEOMFM_03608 9.9e-144 yvbH - - S - - - YvbH-like oligomerisation region
NOGEOMFM_03609 1.61e-156 yvbI - - M - - - Membrane
NOGEOMFM_03610 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
NOGEOMFM_03611 6.87e-106 yvbK - - K - - - acetyltransferase
NOGEOMFM_03612 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NOGEOMFM_03613 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
NOGEOMFM_03614 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NOGEOMFM_03615 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NOGEOMFM_03616 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NOGEOMFM_03617 9.84e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NOGEOMFM_03618 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NOGEOMFM_03619 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
NOGEOMFM_03620 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NOGEOMFM_03622 5.49e-205 yvbU - - K - - - Transcriptional regulator
NOGEOMFM_03623 3.93e-198 yvbV - - EG - - - EamA-like transporter family
NOGEOMFM_03624 1.43e-306 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
NOGEOMFM_03625 1.22e-248 - - - S - - - Glycosyl hydrolase
NOGEOMFM_03626 2.92e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NOGEOMFM_03627 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NOGEOMFM_03628 2.6e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NOGEOMFM_03629 2.52e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NOGEOMFM_03630 7.33e-250 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NOGEOMFM_03631 5.01e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
NOGEOMFM_03632 1.7e-208 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
NOGEOMFM_03633 4.2e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
NOGEOMFM_03634 2.93e-263 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
NOGEOMFM_03635 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
NOGEOMFM_03636 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
NOGEOMFM_03637 1.1e-193 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
NOGEOMFM_03638 2.15e-300 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
NOGEOMFM_03639 1.68e-294 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
NOGEOMFM_03640 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_03641 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
NOGEOMFM_03642 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
NOGEOMFM_03643 3.35e-304 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NOGEOMFM_03644 5.69e-44 yvfG - - S - - - YvfG protein
NOGEOMFM_03645 7.54e-241 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
NOGEOMFM_03646 1.91e-281 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
NOGEOMFM_03647 8.22e-77 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NOGEOMFM_03648 7.83e-140 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NOGEOMFM_03649 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NOGEOMFM_03650 2.36e-246 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
NOGEOMFM_03651 4.13e-254 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
NOGEOMFM_03652 3.5e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NOGEOMFM_03653 3.59e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
NOGEOMFM_03654 5.9e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
NOGEOMFM_03655 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
NOGEOMFM_03656 4.5e-281 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
NOGEOMFM_03657 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
NOGEOMFM_03658 7.94e-150 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NOGEOMFM_03659 1.61e-157 epsA - - M ko:K19420 - ko00000 biosynthesis protein
NOGEOMFM_03660 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
NOGEOMFM_03661 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
NOGEOMFM_03663 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
NOGEOMFM_03664 4.48e-96 - - - S - - - Protein of unknown function (DUF3237)
NOGEOMFM_03665 1.69e-160 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NOGEOMFM_03666 0.0 pbpE - - V - - - Beta-lactamase
NOGEOMFM_03667 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
NOGEOMFM_03668 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NOGEOMFM_03669 0.0 ybeC - - E - - - amino acid
NOGEOMFM_03670 1.17e-137 yvdT_1 - - K - - - Transcriptional regulator
NOGEOMFM_03671 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
NOGEOMFM_03672 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
NOGEOMFM_03673 5.53e-122 yvdQ - - S - - - Protein of unknown function (DUF3231)
NOGEOMFM_03674 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
NOGEOMFM_03675 9.45e-234 - - - S - - - Patatin-like phospholipase
NOGEOMFM_03677 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NOGEOMFM_03678 2.05e-156 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
NOGEOMFM_03679 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
NOGEOMFM_03680 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
NOGEOMFM_03681 3.96e-197 malA - - S - - - Protein of unknown function (DUF1189)
NOGEOMFM_03682 6.84e-190 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
NOGEOMFM_03683 8.65e-311 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
NOGEOMFM_03684 1.63e-299 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
NOGEOMFM_03685 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
NOGEOMFM_03686 1.54e-221 yvdE - - K - - - Transcriptional regulator
NOGEOMFM_03687 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NOGEOMFM_03688 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
NOGEOMFM_03689 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
NOGEOMFM_03690 3.73e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NOGEOMFM_03691 1.15e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NOGEOMFM_03692 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
NOGEOMFM_03693 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_03694 5.37e-249 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
NOGEOMFM_03695 7.75e-171 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NOGEOMFM_03696 1.37e-45 - - - - - - - -
NOGEOMFM_03697 8.35e-185 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
NOGEOMFM_03698 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
NOGEOMFM_03699 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NOGEOMFM_03700 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NOGEOMFM_03701 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NOGEOMFM_03702 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NOGEOMFM_03703 8.31e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NOGEOMFM_03704 2.18e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
NOGEOMFM_03705 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
NOGEOMFM_03706 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NOGEOMFM_03708 0.0 - - - - - - - -
NOGEOMFM_03709 6.36e-172 - - - - - - - -
NOGEOMFM_03710 2.61e-146 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
NOGEOMFM_03711 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NOGEOMFM_03712 1.32e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NOGEOMFM_03713 1.15e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NOGEOMFM_03714 2.87e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
NOGEOMFM_03715 3e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NOGEOMFM_03716 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NOGEOMFM_03717 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NOGEOMFM_03718 5.03e-178 yvpB - - NU - - - protein conserved in bacteria
NOGEOMFM_03719 1.1e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
NOGEOMFM_03720 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NOGEOMFM_03721 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NOGEOMFM_03722 3.72e-211 yvoD - - P - - - COG0370 Fe2 transport system protein B
NOGEOMFM_03723 2.61e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NOGEOMFM_03724 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NOGEOMFM_03725 9.39e-277 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
NOGEOMFM_03726 2.12e-166 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NOGEOMFM_03727 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
NOGEOMFM_03728 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
NOGEOMFM_03729 9.4e-110 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
NOGEOMFM_03730 9.32e-293 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
NOGEOMFM_03731 2.49e-177 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
NOGEOMFM_03732 1.03e-112 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
NOGEOMFM_03733 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
NOGEOMFM_03734 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
NOGEOMFM_03735 2.49e-35 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
NOGEOMFM_03736 1.85e-217 yvlB - - S - - - Putative adhesin
NOGEOMFM_03737 3.3e-64 yvlA - - - - - - -
NOGEOMFM_03738 2.25e-45 yvkN - - - - - - -
NOGEOMFM_03739 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NOGEOMFM_03740 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NOGEOMFM_03741 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NOGEOMFM_03742 2.54e-42 csbA - - S - - - protein conserved in bacteria
NOGEOMFM_03743 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
NOGEOMFM_03744 2.36e-130 yvkB - - K - - - Transcriptional regulator
NOGEOMFM_03745 5.24e-296 yvkA - - P - - - -transporter
NOGEOMFM_03746 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NOGEOMFM_03747 1.38e-73 swrA - - S - - - Swarming motility protein
NOGEOMFM_03748 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NOGEOMFM_03749 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NOGEOMFM_03750 3.03e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
NOGEOMFM_03751 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
NOGEOMFM_03752 6.5e-185 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
NOGEOMFM_03753 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NOGEOMFM_03754 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NOGEOMFM_03755 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NOGEOMFM_03756 9.14e-88 - - - - - - - -
NOGEOMFM_03757 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
NOGEOMFM_03758 8.56e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
NOGEOMFM_03759 8.97e-313 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NOGEOMFM_03760 1.62e-69 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
NOGEOMFM_03761 1.43e-124 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NOGEOMFM_03762 5.02e-39 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NOGEOMFM_03763 5e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NOGEOMFM_03764 6.92e-92 yviE - - - - - - -
NOGEOMFM_03765 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
NOGEOMFM_03766 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
NOGEOMFM_03767 7.06e-102 yvyG - - NOU - - - FlgN protein
NOGEOMFM_03768 4.32e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
NOGEOMFM_03769 1.83e-96 yvyF - - S - - - flagellar protein
NOGEOMFM_03770 7.56e-161 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
NOGEOMFM_03771 1.04e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
NOGEOMFM_03772 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NOGEOMFM_03773 1.77e-198 degV - - S - - - protein conserved in bacteria
NOGEOMFM_03774 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NOGEOMFM_03775 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NOGEOMFM_03776 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
NOGEOMFM_03777 3.81e-223 yvhJ - - K - - - Transcriptional regulator
NOGEOMFM_03778 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NOGEOMFM_03779 3.69e-300 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
NOGEOMFM_03780 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
NOGEOMFM_03781 5.79e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
NOGEOMFM_03782 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
NOGEOMFM_03783 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NOGEOMFM_03784 5.68e-279 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
NOGEOMFM_03785 2.58e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NOGEOMFM_03786 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NOGEOMFM_03787 7e-108 - - - M - - - Glycosyltransferase like family 2
NOGEOMFM_03788 2.25e-265 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
NOGEOMFM_03789 0.0 lytB - - D - - - Stage II sporulation protein
NOGEOMFM_03790 9.07e-16 - - - - - - - -
NOGEOMFM_03791 1.16e-211 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NOGEOMFM_03792 7.71e-277 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NOGEOMFM_03793 2.94e-103 - - - M - - - Glycosyltransferase like family 2
NOGEOMFM_03794 3.05e-119 - - - M - - - Glycosyl transferases group 1
NOGEOMFM_03796 2.74e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NOGEOMFM_03797 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NOGEOMFM_03798 1.95e-167 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
NOGEOMFM_03799 7.8e-102 - - - - - - - -
NOGEOMFM_03800 5.37e-68 - - - - - - - -
NOGEOMFM_03801 7.58e-249 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NOGEOMFM_03802 4.14e-106 - - - M - - - Glycosyltransferase like family 2
NOGEOMFM_03803 6.53e-180 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NOGEOMFM_03804 1.32e-73 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
NOGEOMFM_03805 6.82e-111 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NOGEOMFM_03806 1.01e-129 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NOGEOMFM_03807 1.46e-134 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NOGEOMFM_03808 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NOGEOMFM_03809 6.69e-110 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NOGEOMFM_03810 1.42e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NOGEOMFM_03811 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NOGEOMFM_03812 9.14e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NOGEOMFM_03813 3.12e-310 gerBA - - EG ko:K06291,ko:K06310 - ko00000 Spore germination protein
NOGEOMFM_03814 3.4e-238 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
NOGEOMFM_03815 1.95e-251 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
NOGEOMFM_03816 2.27e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NOGEOMFM_03817 1.42e-220 ywtF_2 - - K - - - Transcriptional regulator
NOGEOMFM_03818 4.69e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NOGEOMFM_03819 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NOGEOMFM_03820 2.29e-29 ywtC - - - - - - -
NOGEOMFM_03821 1.1e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NOGEOMFM_03822 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
NOGEOMFM_03823 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
NOGEOMFM_03824 2.68e-227 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
NOGEOMFM_03825 1.85e-206 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NOGEOMFM_03826 4.61e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NOGEOMFM_03827 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NOGEOMFM_03828 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NOGEOMFM_03829 9.04e-204 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
NOGEOMFM_03830 1.62e-118 batE - - T - - - Sh3 type 3 domain protein
NOGEOMFM_03831 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
NOGEOMFM_03832 8.76e-126 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
NOGEOMFM_03833 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
NOGEOMFM_03834 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NOGEOMFM_03835 3.36e-218 alsR - - K - - - LysR substrate binding domain
NOGEOMFM_03836 1.68e-281 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NOGEOMFM_03837 2.5e-161 ywrJ - - - - - - -
NOGEOMFM_03838 1.37e-194 cotB - - - ko:K06325 - ko00000 -
NOGEOMFM_03839 2.64e-268 cotH - - M ko:K06330 - ko00000 Spore Coat
NOGEOMFM_03840 2.17e-16 - - - - - - - -
NOGEOMFM_03841 1.77e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NOGEOMFM_03842 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
NOGEOMFM_03843 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
NOGEOMFM_03844 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
NOGEOMFM_03845 6.44e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
NOGEOMFM_03846 3.51e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
NOGEOMFM_03848 6.11e-129 ywqN - - S - - - NAD(P)H-dependent
NOGEOMFM_03849 3.33e-209 - - - K - - - Transcriptional regulator
NOGEOMFM_03850 8.51e-155 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NOGEOMFM_03851 1.13e-126 - - - - - - - -
NOGEOMFM_03853 2.2e-66 - - - - - - - -
NOGEOMFM_03854 1.29e-97 - - - - - - - -
NOGEOMFM_03855 1.95e-297 ywqJ - - S - - - Pre-toxin TG
NOGEOMFM_03856 4.98e-50 ywqI - - S - - - Family of unknown function (DUF5344)
NOGEOMFM_03858 1.71e-195 ywqG - - S - - - Domain of unknown function (DUF1963)
NOGEOMFM_03859 1.34e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NOGEOMFM_03860 1.18e-178 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
NOGEOMFM_03861 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
NOGEOMFM_03862 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
NOGEOMFM_03863 3.6e-25 - - - - - - - -
NOGEOMFM_03864 0.0 ywqB - - S - - - SWIM zinc finger
NOGEOMFM_03865 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
NOGEOMFM_03866 1.45e-199 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
NOGEOMFM_03867 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NOGEOMFM_03868 1.04e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
NOGEOMFM_03869 3.56e-86 ywpG - - - - - - -
NOGEOMFM_03870 3.59e-88 ywpF - - S - - - YwpF-like protein
NOGEOMFM_03871 6.34e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
NOGEOMFM_03872 2.51e-18 - - - M - - - cell wall anchor domain
NOGEOMFM_03873 1.28e-66 ywpD - - T - - - Histidine kinase
NOGEOMFM_03874 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NOGEOMFM_03875 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NOGEOMFM_03876 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
NOGEOMFM_03877 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NOGEOMFM_03878 9.79e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
NOGEOMFM_03879 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
NOGEOMFM_03880 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
NOGEOMFM_03881 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
NOGEOMFM_03882 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
NOGEOMFM_03883 7.65e-308 ywoF - - P - - - Right handed beta helix region
NOGEOMFM_03884 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
NOGEOMFM_03885 5.39e-307 ywoD - - EGP - - - Major facilitator superfamily
NOGEOMFM_03886 1.04e-133 yjgF - - Q - - - Isochorismatase family
NOGEOMFM_03887 5.04e-101 - - - - - - - -
NOGEOMFM_03888 6.5e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
NOGEOMFM_03889 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
NOGEOMFM_03890 3.48e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
NOGEOMFM_03891 6.63e-95 ywnJ - - S - - - VanZ like family
NOGEOMFM_03892 1.3e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
NOGEOMFM_03893 5.19e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
NOGEOMFM_03894 1.29e-16 ywnC - - S - - - Family of unknown function (DUF5362)
NOGEOMFM_03895 1.43e-91 ywnF - - S - - - Family of unknown function (DUF5392)
NOGEOMFM_03896 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NOGEOMFM_03897 2.31e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
NOGEOMFM_03898 1.24e-77 ywnC - - S - - - Family of unknown function (DUF5362)
NOGEOMFM_03899 1.02e-145 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
NOGEOMFM_03900 4.58e-85 ywnA - - K - - - Transcriptional regulator
NOGEOMFM_03901 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NOGEOMFM_03902 7.55e-82 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
NOGEOMFM_03903 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
NOGEOMFM_03905 1.84e-20 csbD - - K - - - CsbD-like
NOGEOMFM_03906 1.12e-109 ywmF - - S - - - Peptidase M50
NOGEOMFM_03907 1.25e-128 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NOGEOMFM_03908 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NOGEOMFM_03909 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NOGEOMFM_03911 1.02e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NOGEOMFM_03912 1.89e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
NOGEOMFM_03913 9.77e-234 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
NOGEOMFM_03914 1e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NOGEOMFM_03915 2.68e-171 ywmB - - S - - - TATA-box binding
NOGEOMFM_03916 4.54e-45 ywzB - - S - - - membrane
NOGEOMFM_03917 4.84e-112 ywmA - - - - - - -
NOGEOMFM_03918 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NOGEOMFM_03919 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NOGEOMFM_03920 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NOGEOMFM_03921 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NOGEOMFM_03922 9.66e-117 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NOGEOMFM_03923 1.24e-77 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NOGEOMFM_03924 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NOGEOMFM_03925 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NOGEOMFM_03926 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
NOGEOMFM_03927 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NOGEOMFM_03928 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NOGEOMFM_03929 2.9e-122 ywlG - - S - - - Belongs to the UPF0340 family
NOGEOMFM_03930 1.36e-105 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
NOGEOMFM_03931 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NOGEOMFM_03932 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
NOGEOMFM_03933 1.22e-249 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NOGEOMFM_03934 1.04e-99 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
NOGEOMFM_03935 1.55e-150 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
NOGEOMFM_03936 5.61e-73 ywlA - - S - - - Uncharacterised protein family (UPF0715)
NOGEOMFM_03938 7.78e-201 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NOGEOMFM_03939 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NOGEOMFM_03940 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NOGEOMFM_03941 6.01e-117 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NOGEOMFM_03942 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
NOGEOMFM_03943 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
NOGEOMFM_03944 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NOGEOMFM_03945 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
NOGEOMFM_03946 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NOGEOMFM_03947 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
NOGEOMFM_03948 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NOGEOMFM_03949 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NOGEOMFM_03950 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
NOGEOMFM_03951 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
NOGEOMFM_03952 3.86e-119 ywjG - - S - - - Domain of unknown function (DUF2529)
NOGEOMFM_03953 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NOGEOMFM_03954 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NOGEOMFM_03955 1.65e-266 acdA - - I - - - acyl-CoA dehydrogenase
NOGEOMFM_03956 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
NOGEOMFM_03957 9.57e-287 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NOGEOMFM_03958 2.82e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NOGEOMFM_03959 1.32e-57 ywjC - - - - - - -
NOGEOMFM_03960 7.5e-122 ywjB - - H - - - RibD C-terminal domain
NOGEOMFM_03961 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
NOGEOMFM_03962 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NOGEOMFM_03963 1.02e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
NOGEOMFM_03964 6.53e-121 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
NOGEOMFM_03965 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
NOGEOMFM_03966 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NOGEOMFM_03967 3.53e-110 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
NOGEOMFM_03968 1.51e-178 ywiC - - S - - - YwiC-like protein
NOGEOMFM_03969 2.3e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
NOGEOMFM_03970 1.4e-272 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
NOGEOMFM_03971 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NOGEOMFM_03972 4.64e-96 ywiB - - S - - - protein conserved in bacteria
NOGEOMFM_03973 3.71e-12 - - - S - - - Bacteriocin subtilosin A
NOGEOMFM_03974 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
NOGEOMFM_03976 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NOGEOMFM_03977 1.46e-298 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
NOGEOMFM_03978 4.88e-276 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
NOGEOMFM_03979 0.0 - - - L - - - Peptidase, M16
NOGEOMFM_03981 0.0 ywhL - - CO - - - amine dehydrogenase activity
NOGEOMFM_03982 9.47e-275 ywhK - - CO - - - amine dehydrogenase activity
NOGEOMFM_03983 6.56e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
NOGEOMFM_03987 1.3e-10 - - - - - - - -
NOGEOMFM_03990 1.4e-74 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
NOGEOMFM_03992 1.42e-213 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NOGEOMFM_03993 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NOGEOMFM_03994 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NOGEOMFM_03995 5.51e-123 ywhD - - S - - - YwhD family
NOGEOMFM_03996 3.29e-154 ywhC - - S - - - Peptidase family M50
NOGEOMFM_03997 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
NOGEOMFM_03998 1.45e-93 ywhA - - K - - - Transcriptional regulator
NOGEOMFM_03999 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NOGEOMFM_04001 2.66e-263 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
NOGEOMFM_04002 6.12e-20 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
NOGEOMFM_04003 1.28e-102 yffB - - K - - - Transcriptional regulator
NOGEOMFM_04004 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
NOGEOMFM_04005 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
NOGEOMFM_04006 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
NOGEOMFM_04007 5.39e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
NOGEOMFM_04008 3.69e-201 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
NOGEOMFM_04009 2.51e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NOGEOMFM_04010 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_04011 6.8e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
NOGEOMFM_04012 3.43e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
NOGEOMFM_04013 2.37e-176 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
NOGEOMFM_04014 1.74e-294 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
NOGEOMFM_04015 1.85e-266 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
NOGEOMFM_04016 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NOGEOMFM_04017 1.56e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NOGEOMFM_04018 7.2e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NOGEOMFM_04019 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NOGEOMFM_04020 3.12e-274 ywfA - - EGP - - - -transporter
NOGEOMFM_04021 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NOGEOMFM_04022 0.0 rocB - - E - - - arginine degradation protein
NOGEOMFM_04023 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
NOGEOMFM_04024 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NOGEOMFM_04025 1.1e-102 - - - - - - - -
NOGEOMFM_04026 9.16e-114 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
NOGEOMFM_04027 2.44e-206 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NOGEOMFM_04028 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NOGEOMFM_04029 2.6e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NOGEOMFM_04030 2.54e-243 spsG - - M - - - Spore Coat
NOGEOMFM_04031 4.64e-169 spsF - - M ko:K07257 - ko00000 Spore Coat
NOGEOMFM_04032 1.13e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
NOGEOMFM_04033 4.22e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
NOGEOMFM_04034 1.85e-284 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
NOGEOMFM_04035 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
NOGEOMFM_04036 2.32e-186 spsA - - M - - - Spore Coat
NOGEOMFM_04037 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NOGEOMFM_04038 1.59e-78 ywdK - - S - - - small membrane protein
NOGEOMFM_04039 1.86e-303 ywdJ - - F - - - Xanthine uracil
NOGEOMFM_04040 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
NOGEOMFM_04041 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NOGEOMFM_04042 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NOGEOMFM_04043 1.9e-191 ywdF - - S - - - Glycosyltransferase like family 2
NOGEOMFM_04045 8.74e-146 ywdD - - - - - - -
NOGEOMFM_04046 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
NOGEOMFM_04047 7.39e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NOGEOMFM_04048 6.19e-39 ywdA - - - - - - -
NOGEOMFM_04049 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
NOGEOMFM_04050 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NOGEOMFM_04051 8e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
NOGEOMFM_04052 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NOGEOMFM_04054 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NOGEOMFM_04055 3.44e-238 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NOGEOMFM_04056 5.44e-177 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
NOGEOMFM_04057 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NOGEOMFM_04058 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
NOGEOMFM_04059 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NOGEOMFM_04060 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
NOGEOMFM_04061 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NOGEOMFM_04062 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NOGEOMFM_04063 5.11e-49 ydaS - - S - - - membrane
NOGEOMFM_04064 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NOGEOMFM_04065 1.79e-287 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NOGEOMFM_04066 3.33e-77 gtcA - - S - - - GtrA-like protein
NOGEOMFM_04067 4.16e-159 ywcC - - K - - - transcriptional regulator
NOGEOMFM_04069 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
NOGEOMFM_04070 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NOGEOMFM_04071 1.26e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
NOGEOMFM_04072 2.54e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
NOGEOMFM_04073 1.98e-245 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
NOGEOMFM_04074 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
NOGEOMFM_04075 1e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NOGEOMFM_04076 1.32e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NOGEOMFM_04077 2.7e-203 ywbI - - K - - - Transcriptional regulator
NOGEOMFM_04078 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NOGEOMFM_04079 1.21e-143 ywbG - - M - - - effector of murein hydrolase
NOGEOMFM_04080 1.76e-276 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
NOGEOMFM_04081 6.33e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
NOGEOMFM_04082 4e-280 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
NOGEOMFM_04083 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
NOGEOMFM_04084 1.59e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NOGEOMFM_04085 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
NOGEOMFM_04086 1.45e-312 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NOGEOMFM_04087 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NOGEOMFM_04088 4.41e-215 gspA - - M - - - General stress
NOGEOMFM_04089 1.66e-156 ywaF - - S - - - Integral membrane protein
NOGEOMFM_04090 4.18e-113 ywaE - - K - - - Transcriptional regulator
NOGEOMFM_04091 1.56e-297 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NOGEOMFM_04092 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
NOGEOMFM_04093 5.37e-116 - - - K - - - Helix-turn-helix XRE-family like proteins
NOGEOMFM_04094 7.93e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
NOGEOMFM_04095 2.79e-165 - - - EGP - - - Permeases of the major facilitator superfamily
NOGEOMFM_04096 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
NOGEOMFM_04097 5.7e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
NOGEOMFM_04098 1.27e-20 - - - S - - - D-Ala-teichoic acid biosynthesis protein
NOGEOMFM_04099 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NOGEOMFM_04100 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
NOGEOMFM_04101 1.61e-48 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NOGEOMFM_04102 8.26e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NOGEOMFM_04103 8e-176 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
NOGEOMFM_04104 3.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
NOGEOMFM_04105 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NOGEOMFM_04106 1.18e-67 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NOGEOMFM_04107 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NOGEOMFM_04108 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
NOGEOMFM_04109 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
NOGEOMFM_04110 8.94e-28 yxzF - - - - - - -
NOGEOMFM_04111 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NOGEOMFM_04112 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NOGEOMFM_04113 3.23e-270 yxlH - - EGP - - - Major Facilitator Superfamily
NOGEOMFM_04114 8.58e-174 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NOGEOMFM_04115 1.65e-210 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_04116 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
NOGEOMFM_04117 1.75e-43 - - - - - - - -
NOGEOMFM_04118 4.05e-64 yxlC - - S - - - Family of unknown function (DUF5345)
NOGEOMFM_04119 1.06e-123 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NOGEOMFM_04120 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
NOGEOMFM_04121 1.52e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NOGEOMFM_04122 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
NOGEOMFM_04123 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
NOGEOMFM_04124 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
NOGEOMFM_04125 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
NOGEOMFM_04126 3.97e-310 cimH - - C - - - COG3493 Na citrate symporter
NOGEOMFM_04127 0.0 - - - O - - - Peptidase family M48
NOGEOMFM_04129 6.16e-198 yxkH - - G - - - Polysaccharide deacetylase
NOGEOMFM_04130 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NOGEOMFM_04131 3.89e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
NOGEOMFM_04132 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NOGEOMFM_04133 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
NOGEOMFM_04134 1.17e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
NOGEOMFM_04135 4.98e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NOGEOMFM_04136 7.69e-100 - - - S - - - Protein of unknown function (DUF1453)
NOGEOMFM_04137 4.59e-257 - - - T - - - Signal transduction histidine kinase
NOGEOMFM_04138 4.65e-149 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
NOGEOMFM_04139 2.6e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NOGEOMFM_04142 1.43e-111 yxjI - - S - - - LURP-one-related
NOGEOMFM_04143 1.28e-278 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
NOGEOMFM_04144 9.77e-279 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
NOGEOMFM_04145 6.8e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NOGEOMFM_04146 5.91e-151 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NOGEOMFM_04147 3.82e-167 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NOGEOMFM_04148 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
NOGEOMFM_04149 8.81e-204 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
NOGEOMFM_04150 2.1e-269 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NOGEOMFM_04151 2.83e-131 - - - T - - - Domain of unknown function (DUF4163)
NOGEOMFM_04152 5.39e-62 yxiS - - - - - - -
NOGEOMFM_04153 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
NOGEOMFM_04154 3.31e-283 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
NOGEOMFM_04155 1.46e-182 bglS - - M - - - licheninase activity
NOGEOMFM_04156 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
NOGEOMFM_04157 4.37e-142 - - - - - - - -
NOGEOMFM_04158 1.09e-291 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
NOGEOMFM_04159 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NOGEOMFM_04160 2.37e-272 - - - E - - - GDSL-like Lipase/Acylhydrolase
NOGEOMFM_04161 1.86e-70 - - - K - - - Transcriptional regulator PadR-like family
NOGEOMFM_04162 2.16e-53 - - - S - - - Protein of unknown function (DUF2812)
NOGEOMFM_04163 2.34e-21 - - - S - - - YxiJ-like protein
NOGEOMFM_04164 0.0 wapA - - M - - - COG3209 Rhs family protein
NOGEOMFM_04165 8.44e-210 yxxF - - EG - - - EamA-like transporter family
NOGEOMFM_04166 2.2e-28 - - - - - - - -
NOGEOMFM_04167 2.01e-75 - - - K - - - helix_turn_helix, mercury resistance
NOGEOMFM_04169 1.24e-113 - - - - - - - -
NOGEOMFM_04170 2.77e-35 - - - S - - - Sporulation delaying protein SdpA
NOGEOMFM_04171 6.99e-94 yxiE - - T - - - Belongs to the universal stress protein A family
NOGEOMFM_04172 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NOGEOMFM_04173 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NOGEOMFM_04174 1.33e-62 - - - - - - - -
NOGEOMFM_04175 9.25e-103 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
NOGEOMFM_04176 6.09e-292 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
NOGEOMFM_04178 2.81e-26 - - - S - - - protein conserved in bacteria
NOGEOMFM_04180 2.14e-156 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
NOGEOMFM_04181 4.47e-51 yxiC - - S - - - Family of unknown function (DUF5344)
NOGEOMFM_04182 2.18e-36 - - - S - - - Domain of unknown function (DUF5082)
NOGEOMFM_04183 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
NOGEOMFM_04184 4.06e-102 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NOGEOMFM_04185 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
NOGEOMFM_04186 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NOGEOMFM_04187 2.61e-298 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
NOGEOMFM_04188 8.04e-230 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NOGEOMFM_04189 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NOGEOMFM_04190 6.66e-298 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
NOGEOMFM_04191 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NOGEOMFM_04192 4.8e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NOGEOMFM_04193 1.22e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NOGEOMFM_04194 1.76e-195 - - - S - - - Domain of Unknown Function (DUF1206)
NOGEOMFM_04195 7.72e-256 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
NOGEOMFM_04196 1.39e-312 yxeQ - - S - - - MmgE/PrpD family
NOGEOMFM_04197 2.65e-268 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
NOGEOMFM_04198 2.78e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_04199 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
NOGEOMFM_04200 5.02e-185 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
NOGEOMFM_04201 1.54e-121 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NOGEOMFM_04202 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NOGEOMFM_04203 9.11e-236 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
NOGEOMFM_04204 1.4e-194 yxeH - - S - - - hydrolases of the HAD superfamily
NOGEOMFM_04207 7.32e-42 yxeE - - - - - - -
NOGEOMFM_04208 7.57e-28 yxeD - - - - - - -
NOGEOMFM_04209 6.79e-91 - - - - - - - -
NOGEOMFM_04210 4.99e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NOGEOMFM_04211 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
NOGEOMFM_04212 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
NOGEOMFM_04213 9.39e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NOGEOMFM_04214 2.7e-231 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NOGEOMFM_04215 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NOGEOMFM_04216 2.83e-204 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NOGEOMFM_04217 1.96e-194 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NOGEOMFM_04218 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
NOGEOMFM_04219 1.55e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NOGEOMFM_04220 4.68e-295 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
NOGEOMFM_04221 1.74e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NOGEOMFM_04222 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NOGEOMFM_04223 6.09e-228 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NOGEOMFM_04224 9.89e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NOGEOMFM_04225 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NOGEOMFM_04226 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
NOGEOMFM_04227 3.52e-224 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
NOGEOMFM_04229 2.13e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
NOGEOMFM_04230 2.4e-312 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NOGEOMFM_04231 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
NOGEOMFM_04233 8.38e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NOGEOMFM_04234 1.03e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
NOGEOMFM_04235 2.4e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NOGEOMFM_04236 2.09e-16 yxaI - - S - - - membrane protein domain
NOGEOMFM_04237 1.73e-135 yxaL - - S - - - PQQ-like domain
NOGEOMFM_04238 1.96e-83 - - - S - - - Family of unknown function (DUF5391)
NOGEOMFM_04239 4.03e-99 yxaI - - S - - - membrane protein domain
NOGEOMFM_04240 6.77e-289 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
NOGEOMFM_04241 1e-248 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
NOGEOMFM_04242 7.9e-130 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
NOGEOMFM_04243 5.01e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NOGEOMFM_04244 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
NOGEOMFM_04245 5.96e-77 - - - S ko:K06518 - ko00000,ko02000 LrgA family
NOGEOMFM_04246 7.33e-152 yxaC - - M - - - effector of murein hydrolase
NOGEOMFM_04247 7.3e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
NOGEOMFM_04248 1.64e-263 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NOGEOMFM_04249 2.56e-163 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
NOGEOMFM_04250 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NOGEOMFM_04251 5.87e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
NOGEOMFM_04252 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NOGEOMFM_04253 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
NOGEOMFM_04254 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
NOGEOMFM_04255 5.52e-238 - - - S - - - Polysaccharide pyruvyl transferase
NOGEOMFM_04256 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
NOGEOMFM_04257 8.38e-44 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
NOGEOMFM_04258 1.23e-162 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
NOGEOMFM_04259 2.4e-23 - - - - - - - -
NOGEOMFM_04260 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
NOGEOMFM_04261 0.0 - - - L - - - AAA domain
NOGEOMFM_04262 6.93e-310 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NOGEOMFM_04263 3.64e-56 - - - S - - - MazG-like family
NOGEOMFM_04264 1.36e-141 - - - S - - - Caspase domain
NOGEOMFM_04265 1.23e-134 - - - L - - - reverse transcriptase
NOGEOMFM_04267 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NOGEOMFM_04269 8.12e-90 - - - - - - - -
NOGEOMFM_04270 1.81e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NOGEOMFM_04272 2.24e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
NOGEOMFM_04273 1.01e-271 yycP - - - - - - -
NOGEOMFM_04274 1.68e-169 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NOGEOMFM_04275 5.25e-111 yycN - - K - - - Acetyltransferase
NOGEOMFM_04276 1.06e-239 - - - S - - - aspartate phosphatase
NOGEOMFM_04278 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
NOGEOMFM_04279 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
NOGEOMFM_04280 8.29e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
NOGEOMFM_04281 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NOGEOMFM_04282 5.58e-216 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
NOGEOMFM_04283 2.36e-122 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
NOGEOMFM_04284 9.34e-98 - - - S - - - Peptidase propeptide and YPEB domain
NOGEOMFM_04285 2.2e-42 - - - S - - - Peptidase propeptide and YPEB domain
NOGEOMFM_04286 1.56e-277 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NOGEOMFM_04287 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NOGEOMFM_04288 2.83e-199 yycI - - S - - - protein conserved in bacteria
NOGEOMFM_04289 0.0 yycH - - S - - - protein conserved in bacteria
NOGEOMFM_04290 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NOGEOMFM_04291 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NOGEOMFM_04296 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NOGEOMFM_04297 3.85e-98 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NOGEOMFM_04298 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NOGEOMFM_04299 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
NOGEOMFM_04301 1.89e-22 yycC - - K - - - YycC-like protein
NOGEOMFM_04302 4.19e-283 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
NOGEOMFM_04303 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NOGEOMFM_04304 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NOGEOMFM_04305 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NOGEOMFM_04306 8.66e-204 yybS - - S - - - membrane
NOGEOMFM_04308 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
NOGEOMFM_04309 1.3e-87 yybR - - K - - - Transcriptional regulator
NOGEOMFM_04310 4.89e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
NOGEOMFM_04311 3.67e-80 - - - - - - - -
NOGEOMFM_04313 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NOGEOMFM_04314 1.46e-140 - - - K - - - TipAS antibiotic-recognition domain
NOGEOMFM_04315 2.05e-183 - - - - - - - -
NOGEOMFM_04316 2.49e-87 - - - S - - - SnoaL-like domain
NOGEOMFM_04317 5.67e-162 yybG - - S - - - Pentapeptide repeat-containing protein
NOGEOMFM_04318 8.32e-275 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
NOGEOMFM_04319 1.31e-210 yybE - - K - - - Transcriptional regulator
NOGEOMFM_04320 1.26e-100 yjcF - - S - - - Acetyltransferase (GNAT) domain
NOGEOMFM_04321 1.94e-94 yybC - - - - - - -
NOGEOMFM_04322 1.77e-161 - - - S - - - Metallo-beta-lactamase superfamily
NOGEOMFM_04323 4.54e-100 yybA - - K - - - transcriptional
NOGEOMFM_04324 2.85e-93 yjcF - - S - - - Acetyltransferase (GNAT) domain
NOGEOMFM_04325 1.74e-124 yyaS - - S ko:K07149 - ko00000 Membrane
NOGEOMFM_04326 1.84e-117 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
NOGEOMFM_04327 1.23e-84 - - - S - - - YjbR
NOGEOMFM_04328 7.09e-136 yyaP - - H - - - RibD C-terminal domain
NOGEOMFM_04329 0.0 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
NOGEOMFM_04330 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
NOGEOMFM_04331 4.94e-214 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
NOGEOMFM_04332 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
NOGEOMFM_04333 1.55e-128 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
NOGEOMFM_04334 9.85e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NOGEOMFM_04335 6.85e-227 ccpB - - K - - - Transcriptional regulator
NOGEOMFM_04336 4.68e-184 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NOGEOMFM_04337 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NOGEOMFM_04338 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NOGEOMFM_04339 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NOGEOMFM_04340 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NOGEOMFM_04341 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NOGEOMFM_04342 7.41e-45 yyzM - - S - - - protein conserved in bacteria
NOGEOMFM_04343 5.34e-227 yyaD - - S - - - Membrane
NOGEOMFM_04344 4.53e-145 yyaC - - S - - - Sporulation protein YyaC
NOGEOMFM_04345 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NOGEOMFM_04346 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
NOGEOMFM_04347 9.26e-98 - - - S - - - Bacterial PH domain
NOGEOMFM_04348 2.58e-192 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NOGEOMFM_04349 5.86e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NOGEOMFM_04350 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NOGEOMFM_04351 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NOGEOMFM_04352 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
NOGEOMFM_04353 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NOGEOMFM_04354 5.7e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NOGEOMFM_04356 1.37e-94 - - - L - - - integrase family
NOGEOMFM_04359 4.22e-23 - - - S - - - 3D domain
NOGEOMFM_04360 1.18e-67 - - - S - - - DNA ligase (ATP) activity
NOGEOMFM_04362 2.05e-103 - - - - - - - -
NOGEOMFM_04364 1.72e-226 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
NOGEOMFM_04367 0.000231 - - - L - - - Phage terminase small Subunit
NOGEOMFM_04370 3.23e-56 - - - S - - - endonuclease activity
NOGEOMFM_04371 3.22e-164 - - - S - - - Phage Terminase
NOGEOMFM_04372 1.82e-131 - - - S - - - Phage portal protein
NOGEOMFM_04373 4.5e-65 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
NOGEOMFM_04374 1.96e-109 - - - S - - - Phage capsid family
NOGEOMFM_04376 0.000105 - - - S - - - Phage gp6-like head-tail connector protein
NOGEOMFM_04380 2.66e-52 - - - S - - - Phage tail tube protein
NOGEOMFM_04382 1.12e-174 - - - D - - - Phage tail tape measure protein
NOGEOMFM_04383 1.62e-239 - - - S - - - Phage tail protein
NOGEOMFM_04384 3.46e-159 - - - S - - - peptidoglycan catabolic process
NOGEOMFM_04386 1.37e-84 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
NOGEOMFM_04391 4.38e-150 - - - M - - - Glycosyl hydrolases family 25
NOGEOMFM_04392 5.22e-122 - - - S - - - Phage integrase family
NOGEOMFM_04393 3.38e-242 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
NOGEOMFM_04394 7.45e-82 - - - S - - - Immunity protein 70
NOGEOMFM_04396 1.62e-76 - - - - - - - -
NOGEOMFM_04404 6.82e-71 - - - L - - - Domain of unknown function (DUF1738)
NOGEOMFM_04405 6.66e-181 - - - S - - - DNA gyrase/topoisomerase IV, subunit A
NOGEOMFM_04406 1.41e-229 - - - S - - - DNA gyrase B
NOGEOMFM_04407 5.92e-17 - - - S - - - Replication initiator protein A (RepA) N-terminus
NOGEOMFM_04415 7.95e-18 - - - F - - - Guanylate kinase homologues.
NOGEOMFM_04419 0.0 - - - S - - - Bacterial DNA polymerase III alpha subunit
NOGEOMFM_04423 4.61e-60 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NOGEOMFM_04429 2.57e-13 M1-624 - - K - - - Transcriptional regulator
NOGEOMFM_04430 2.46e-101 - - - S - - - exonuclease activity
NOGEOMFM_04432 4.79e-111 - - - S - - - DNA primase activity
NOGEOMFM_04433 7.74e-133 - - - S - - - DNA helicase activity
NOGEOMFM_04434 1.21e-11 - - - - - - - -
NOGEOMFM_04437 2.45e-51 - - - - - - - -
NOGEOMFM_04440 7.45e-130 - - - S - - - Ribonucleotide reductase, small chain
NOGEOMFM_04441 0.0 - - - S - - - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
NOGEOMFM_04442 2.72e-80 - - - S - - - AAA domain
NOGEOMFM_04445 2.56e-62 - - - F - - - Nucleoside 2-deoxyribosyltransferase
NOGEOMFM_04449 2.2e-43 yxcD - - S - - - Protein of unknown function (DUF2653)
NOGEOMFM_04451 5.79e-19 - - - - - - - -
NOGEOMFM_04452 3.05e-53 - - - S ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphoribosyl-ATP pyrophosphohydrolase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)