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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
OPOHKMFD_00001	3.32e-24	-	-	-	-	-	-	-	-
OPOHKMFD_00003	1.85e-40	-	-	-	S	-	-	-	BhlA holin family
OPOHKMFD_00004	8.42e-67	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
OPOHKMFD_00005	3e-45	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
OPOHKMFD_00008	5.95e-73	-	-	-	-	-	-	-	-
OPOHKMFD_00011	5.18e-127	-	-	-	K	-	-	-	Helix-turn-helix domain
OPOHKMFD_00012	6.77e-181	ysnF	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_00013	1.55e-44	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
OPOHKMFD_00015	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
OPOHKMFD_00016	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
OPOHKMFD_00017	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OPOHKMFD_00018	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OPOHKMFD_00019	8.67e-255	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
OPOHKMFD_00020	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OPOHKMFD_00021	4.4e-149	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OPOHKMFD_00022	3.19e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
OPOHKMFD_00023	2.54e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
OPOHKMFD_00024	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OPOHKMFD_00025	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
OPOHKMFD_00026	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OPOHKMFD_00027	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
OPOHKMFD_00028	4.77e-116	ysxD	-	-	-	-	-	-	-
OPOHKMFD_00029	6.39e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OPOHKMFD_00030	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
OPOHKMFD_00031	8.91e-220	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
OPOHKMFD_00032	1.23e-184	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
OPOHKMFD_00033	3.7e-233	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
OPOHKMFD_00034	3.53e-312	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
OPOHKMFD_00035	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
OPOHKMFD_00036	2.79e-251	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OPOHKMFD_00037	1.53e-35	-	-	-	-	-	-	-	-
OPOHKMFD_00038	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
OPOHKMFD_00039	1.83e-314	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
OPOHKMFD_00040	1.28e-108	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
OPOHKMFD_00041	3.91e-207	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
OPOHKMFD_00042	1.66e-130	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
OPOHKMFD_00043	1.39e-161	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
OPOHKMFD_00044	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
OPOHKMFD_00045	7.78e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
OPOHKMFD_00046	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
OPOHKMFD_00047	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
OPOHKMFD_00048	2.91e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
OPOHKMFD_00049	1.23e-185	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
OPOHKMFD_00050	3.74e-208	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
OPOHKMFD_00051	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
OPOHKMFD_00052	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
OPOHKMFD_00053	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
OPOHKMFD_00054	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
OPOHKMFD_00055	5.59e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OPOHKMFD_00056	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
OPOHKMFD_00057	1.43e-208	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
OPOHKMFD_00058	5.02e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
OPOHKMFD_00059	2.36e-290	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
OPOHKMFD_00060	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
OPOHKMFD_00061	8.4e-201	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
OPOHKMFD_00062	1.32e-271	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OPOHKMFD_00063	2.43e-217	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
OPOHKMFD_00064	2.55e-70	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OPOHKMFD_00065	8.63e-165	yebC	-	-	K	-	-	-	transcriptional regulatory protein
OPOHKMFD_00066	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
OPOHKMFD_00067	6.26e-68	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
OPOHKMFD_00069	1.91e-151	yrzF	-	-	T	-	-	-	serine threonine protein kinase
OPOHKMFD_00070	4.59e-247	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
OPOHKMFD_00071	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
OPOHKMFD_00072	1.85e-120	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
OPOHKMFD_00073	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
OPOHKMFD_00074	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
OPOHKMFD_00075	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
OPOHKMFD_00076	6.03e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OPOHKMFD_00077	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
OPOHKMFD_00078	1.29e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
OPOHKMFD_00079	1.46e-96	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
OPOHKMFD_00080	5.83e-143	yrbG	-	-	S	-	-	-	membrane
OPOHKMFD_00081	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OPOHKMFD_00082	5.53e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
OPOHKMFD_00083	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OPOHKMFD_00084	2.65e-113	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
OPOHKMFD_00085	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
OPOHKMFD_00086	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
OPOHKMFD_00087	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OPOHKMFD_00088	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OPOHKMFD_00089	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
OPOHKMFD_00090	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
OPOHKMFD_00092	7.06e-309	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
OPOHKMFD_00093	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OPOHKMFD_00094	2.29e-176	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
OPOHKMFD_00095	6.69e-301	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
OPOHKMFD_00096	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_00097	2.98e-269	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
OPOHKMFD_00098	5.64e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
OPOHKMFD_00099	1.02e-38	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
OPOHKMFD_00100	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
OPOHKMFD_00101	1.44e-107	yrrD	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_00102	8.4e-42	yrzR	-	-	-	-	-	-	-
OPOHKMFD_00103	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
OPOHKMFD_00104	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
OPOHKMFD_00105	3.24e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
OPOHKMFD_00106	1.01e-184	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
OPOHKMFD_00107	2.21e-168	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
OPOHKMFD_00108	1.25e-241	yrrI	-	-	S	-	-	-	AI-2E family transporter
OPOHKMFD_00109	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OPOHKMFD_00110	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
OPOHKMFD_00111	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OPOHKMFD_00112	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
OPOHKMFD_00113	7.51e-242	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OPOHKMFD_00114	1.98e-154	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
OPOHKMFD_00115	6.3e-222	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
OPOHKMFD_00116	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
OPOHKMFD_00117	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
OPOHKMFD_00118	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OPOHKMFD_00119	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
OPOHKMFD_00120	1.42e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
OPOHKMFD_00121	4.94e-36	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
OPOHKMFD_00122	3.44e-153	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
OPOHKMFD_00123	1.97e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OPOHKMFD_00124	1.66e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
OPOHKMFD_00125	8.55e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
OPOHKMFD_00126	6.93e-49	yrhC	-	-	S	-	-	-	YrhC-like protein
OPOHKMFD_00127	3.5e-102	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
OPOHKMFD_00128	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
OPOHKMFD_00129	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
OPOHKMFD_00130	1.38e-183	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
OPOHKMFD_00132	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
OPOHKMFD_00133	8.67e-124	yrhH	-	-	Q	-	-	-	methyltransferase
OPOHKMFD_00134	2.26e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
OPOHKMFD_00135	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
OPOHKMFD_00136	6.32e-59	yrhK	-	-	S	-	-	-	YrhK-like protein
OPOHKMFD_00137	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
OPOHKMFD_00138	1.12e-187	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
OPOHKMFD_00139	5.77e-113	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
OPOHKMFD_00140	5.9e-194	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
OPOHKMFD_00141	4.63e-136	yrhP	-	-	E	-	-	-	LysE type translocator
OPOHKMFD_00142	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
OPOHKMFD_00143	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
OPOHKMFD_00144	5.36e-97	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
OPOHKMFD_00145	7.63e-107	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
OPOHKMFD_00146	6.11e-168	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
OPOHKMFD_00147	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
OPOHKMFD_00148	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
OPOHKMFD_00149	2.25e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
OPOHKMFD_00150	4.81e-253	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
OPOHKMFD_00151	2.9e-10	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
OPOHKMFD_00152	1.83e-67	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
OPOHKMFD_00153	7.23e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
OPOHKMFD_00154	1.23e-35	yraE	-	-	-	ko:K06440	-	ko00000	-
OPOHKMFD_00155	4.84e-279	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OPOHKMFD_00156	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
OPOHKMFD_00157	4.19e-50	yraG	-	-	-	ko:K06440	-	ko00000	-
OPOHKMFD_00158	3.15e-85	-	-	-	E	-	-	-	Glyoxalase-like domain
OPOHKMFD_00159	1.44e-79	-	-	-	T	-	-	-	sh3 domain protein
OPOHKMFD_00160	7.73e-79	-	-	-	T	-	-	-	sh3 domain protein
OPOHKMFD_00161	6.66e-192	-	-	-	S	-	-	-	Alpha beta hydrolase
OPOHKMFD_00162	1.45e-55	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OPOHKMFD_00163	3.87e-200	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
OPOHKMFD_00164	5.95e-263	yraM	-	-	S	-	-	-	PrpF protein
OPOHKMFD_00165	2.97e-210	yraN	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_00166	5.31e-286	yraO	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
OPOHKMFD_00167	5.96e-240	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
OPOHKMFD_00168	2.92e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
OPOHKMFD_00169	7.31e-167	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
OPOHKMFD_00170	1.51e-85	napB	-	-	K	-	-	-	MarR family transcriptional regulator
OPOHKMFD_00171	7.88e-281	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
OPOHKMFD_00173	5.45e-176	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG3959 Transketolase, N-terminal subunit
OPOHKMFD_00174	2.91e-192	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
OPOHKMFD_00175	3.43e-145	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPOHKMFD_00176	2.76e-266	-	-	-	P	-	-	-	Major Facilitator Superfamily
OPOHKMFD_00178	2.34e-128	-	-	-	K	ko:K05799	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
OPOHKMFD_00179	2.39e-162	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
OPOHKMFD_00180	1.56e-184	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
OPOHKMFD_00181	4.23e-246	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
OPOHKMFD_00182	8.54e-212	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
OPOHKMFD_00183	2.01e-118	yrdA	-	-	S	-	-	-	DinB family
OPOHKMFD_00184	1.04e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
OPOHKMFD_00185	2.11e-130	yrdC	-	-	Q	-	-	-	Isochorismatase family
OPOHKMFD_00187	3.11e-289	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
OPOHKMFD_00188	7.91e-55	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
OPOHKMFD_00189	4.82e-103	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
OPOHKMFD_00190	6.57e-176	azlC	-	-	E	-	-	-	AzlC protein
OPOHKMFD_00191	1.97e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
OPOHKMFD_00192	2.03e-291	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
OPOHKMFD_00194	6e-213	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
OPOHKMFD_00195	1.23e-253	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
OPOHKMFD_00196	1.15e-202	-	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_00197	2.84e-215	yrdR	-	-	EG	-	-	-	EamA-like transporter family
OPOHKMFD_00198	2.45e-23	-	-	-	S	-	-	-	YrzO-like protein
OPOHKMFD_00199	1.33e-293	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
OPOHKMFD_00200	2.16e-108	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
OPOHKMFD_00201	2.17e-268	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
OPOHKMFD_00202	4.42e-185	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
OPOHKMFD_00203	1.28e-137	yrkC	-	-	G	-	-	-	Cupin domain
OPOHKMFD_00204	3.32e-28	-	-	-	-	-	-	-	-
OPOHKMFD_00205	4.38e-52	yrkD	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_00206	6.83e-109	yrkE	-	-	O	-	-	-	DsrE/DsrF/DrsH-like family
OPOHKMFD_00207	4.61e-126	yrkF	-	-	OP	-	-	-	Belongs to the sulfur carrier protein TusA family
OPOHKMFD_00208	0.000112	perX	-	-	S	-	-	-	DsrE/DsrF-like family
OPOHKMFD_00209	9.59e-269	yrkH	-	-	P	-	-	-	Rhodanese Homology Domain
OPOHKMFD_00210	6.46e-49	yrkI	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
OPOHKMFD_00211	6.63e-162	yrkJ	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
OPOHKMFD_00212	2.21e-102	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
OPOHKMFD_00213	4.7e-125	yrkL	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
OPOHKMFD_00214	8.99e-133	yrkN	-	-	K	-	-	-	Acetyltransferase (GNAT) family
OPOHKMFD_00215	7.21e-281	yrkO	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
OPOHKMFD_00216	7.15e-164	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
OPOHKMFD_00217	4.05e-303	yrkQ	-	-	T	-	-	-	Histidine kinase
OPOHKMFD_00218	1.48e-81	psiE	-	-	S	ko:K13256	-	ko00000	Protein PsiE homolog
OPOHKMFD_00219	7.53e-161	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OPOHKMFD_00220	7.25e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
OPOHKMFD_00221	5.21e-168	-	-	-	-	-	-	-	-
OPOHKMFD_00222	8.54e-214	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
OPOHKMFD_00223	8.6e-131	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
OPOHKMFD_00224	2.05e-177	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
OPOHKMFD_00225	1.84e-181	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
OPOHKMFD_00227	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
OPOHKMFD_00228	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
OPOHKMFD_00229	8.1e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OPOHKMFD_00230	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
OPOHKMFD_00231	2.47e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OPOHKMFD_00232	4.81e-133	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
OPOHKMFD_00233	1.14e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
OPOHKMFD_00234	4.66e-177	yqeM	-	-	Q	-	-	-	Methyltransferase
OPOHKMFD_00235	2.69e-189	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OPOHKMFD_00236	2.35e-127	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
OPOHKMFD_00237	2.67e-136	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
OPOHKMFD_00238	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
OPOHKMFD_00239	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
OPOHKMFD_00240	9.55e-243	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
OPOHKMFD_00241	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
OPOHKMFD_00242	4.16e-259	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OPOHKMFD_00243	9.53e-284	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
OPOHKMFD_00244	6.28e-73	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
OPOHKMFD_00245	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
OPOHKMFD_00246	2.9e-276	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
OPOHKMFD_00247	1.65e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
OPOHKMFD_00248	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OPOHKMFD_00249	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
OPOHKMFD_00250	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
OPOHKMFD_00251	5.63e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
OPOHKMFD_00252	1.01e-180	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
OPOHKMFD_00253	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
OPOHKMFD_00254	4.02e-201	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
OPOHKMFD_00255	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
OPOHKMFD_00256	2.25e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
OPOHKMFD_00257	7.97e-292	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
OPOHKMFD_00258	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
OPOHKMFD_00259	1.4e-66	yqfB	-	-	-	-	-	-	-
OPOHKMFD_00260	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
OPOHKMFD_00261	1.21e-241	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
OPOHKMFD_00262	4.99e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
OPOHKMFD_00264	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
OPOHKMFD_00265	7.14e-105	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OPOHKMFD_00266	1.16e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
OPOHKMFD_00267	6.71e-93	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
OPOHKMFD_00268	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OPOHKMFD_00269	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
OPOHKMFD_00270	5.26e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
OPOHKMFD_00271	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
OPOHKMFD_00272	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
OPOHKMFD_00273	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
OPOHKMFD_00274	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
OPOHKMFD_00275	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
OPOHKMFD_00276	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
OPOHKMFD_00277	2.79e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
OPOHKMFD_00278	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
OPOHKMFD_00279	1.1e-146	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
OPOHKMFD_00280	1.08e-268	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OPOHKMFD_00281	1.75e-226	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OPOHKMFD_00282	3.36e-49	yqfQ	-	-	S	-	-	-	YqfQ-like protein
OPOHKMFD_00283	3.13e-310	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
OPOHKMFD_00284	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OPOHKMFD_00285	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
OPOHKMFD_00286	3.83e-199	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
OPOHKMFD_00287	8.59e-107	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
OPOHKMFD_00288	4.78e-141	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
OPOHKMFD_00289	2.04e-81	yqfX	-	-	S	-	-	-	membrane
OPOHKMFD_00290	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OPOHKMFD_00291	1.35e-61	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
OPOHKMFD_00292	2.74e-168	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
OPOHKMFD_00293	8.25e-101	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
OPOHKMFD_00294	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
OPOHKMFD_00295	3.96e-293	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
OPOHKMFD_00296	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
OPOHKMFD_00297	4.32e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
OPOHKMFD_00298	7.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
OPOHKMFD_00299	8.71e-201	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
OPOHKMFD_00300	9.78e-190	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OPOHKMFD_00301	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OPOHKMFD_00302	6.33e-93	yqzC	-	-	S	-	-	-	YceG-like family
OPOHKMFD_00303	3.42e-68	yqzD	-	-	-	-	-	-	-
OPOHKMFD_00305	1.05e-252	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
OPOHKMFD_00306	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
OPOHKMFD_00307	4.27e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OPOHKMFD_00308	3.38e-14	yqgO	-	-	-	-	-	-	-
OPOHKMFD_00309	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
OPOHKMFD_00310	1.07e-43	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
OPOHKMFD_00311	2.31e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
OPOHKMFD_00312	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
OPOHKMFD_00313	4.14e-281	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
OPOHKMFD_00314	5.42e-256	yqgU	-	-	-	-	-	-	-
OPOHKMFD_00315	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
OPOHKMFD_00316	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
OPOHKMFD_00317	1.3e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
OPOHKMFD_00318	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
OPOHKMFD_00319	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
OPOHKMFD_00321	8.33e-191	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OPOHKMFD_00322	1.36e-303	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
OPOHKMFD_00323	1.51e-233	yqxL	-	-	P	-	-	-	Mg2 transporter protein
OPOHKMFD_00324	3.73e-09	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
OPOHKMFD_00326	9.05e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OPOHKMFD_00327	8.73e-219	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
OPOHKMFD_00328	3.09e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
OPOHKMFD_00329	1.05e-88	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
OPOHKMFD_00330	4.35e-79	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
OPOHKMFD_00331	9.65e-59	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
OPOHKMFD_00332	3.24e-58	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
OPOHKMFD_00333	3.33e-35	yqzE	-	-	S	-	-	-	YqzE-like protein
OPOHKMFD_00334	6.36e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
OPOHKMFD_00335	8e-156	yqxM	-	-	-	ko:K19433	-	ko00000	-
OPOHKMFD_00336	4.27e-97	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
OPOHKMFD_00337	9e-182	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
OPOHKMFD_00338	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
OPOHKMFD_00339	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
OPOHKMFD_00340	9.14e-197	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
OPOHKMFD_00341	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
OPOHKMFD_00342	8.13e-263	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
OPOHKMFD_00343	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OPOHKMFD_00344	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OPOHKMFD_00345	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
OPOHKMFD_00346	9.17e-204	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
OPOHKMFD_00347	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
OPOHKMFD_00348	4.93e-210	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
OPOHKMFD_00349	5.18e-81	yqhP	-	-	-	-	-	-	-
OPOHKMFD_00350	2.98e-220	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
OPOHKMFD_00351	9.37e-120	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
OPOHKMFD_00352	2.75e-100	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
OPOHKMFD_00353	2.99e-249	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
OPOHKMFD_00354	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OPOHKMFD_00355	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
OPOHKMFD_00356	1.66e-216	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
OPOHKMFD_00357	9.44e-110	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
OPOHKMFD_00358	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
OPOHKMFD_00359	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
OPOHKMFD_00360	7.65e-257	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
OPOHKMFD_00361	1.28e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
OPOHKMFD_00362	1.08e-148	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
OPOHKMFD_00363	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
OPOHKMFD_00364	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
OPOHKMFD_00365	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
OPOHKMFD_00366	9.55e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_00367	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OPOHKMFD_00368	1.07e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OPOHKMFD_00369	3.55e-312	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OPOHKMFD_00370	1.09e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OPOHKMFD_00371	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
OPOHKMFD_00372	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OPOHKMFD_00373	1.77e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
OPOHKMFD_00374	3.08e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
OPOHKMFD_00375	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
OPOHKMFD_00376	5.12e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
OPOHKMFD_00377	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
OPOHKMFD_00379	3.72e-131	-	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
OPOHKMFD_00380	4.7e-246	-	-	-	O	-	-	-	Subtilase family
OPOHKMFD_00383	1.98e-273	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
OPOHKMFD_00384	4.74e-37	-	-	-	-	-	-	-	-
OPOHKMFD_00385	9.4e-138	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
OPOHKMFD_00386	3.39e-168	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
OPOHKMFD_00387	1.83e-277	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
OPOHKMFD_00388	3.99e-198	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
OPOHKMFD_00389	2.86e-267	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
OPOHKMFD_00390	1.85e-264	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
OPOHKMFD_00391	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
OPOHKMFD_00392	4.18e-207	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OPOHKMFD_00393	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
OPOHKMFD_00394	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
OPOHKMFD_00395	1.74e-198	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
OPOHKMFD_00396	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
OPOHKMFD_00397	1.18e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
OPOHKMFD_00398	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OPOHKMFD_00399	2.24e-237	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OPOHKMFD_00400	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OPOHKMFD_00401	8.87e-287	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OPOHKMFD_00402	6.38e-195	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
OPOHKMFD_00403	3.09e-267	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
OPOHKMFD_00404	9.96e-213	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OPOHKMFD_00405	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
OPOHKMFD_00406	1.43e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
OPOHKMFD_00407	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
OPOHKMFD_00408	5.2e-166	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
OPOHKMFD_00409	1.09e-224	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
OPOHKMFD_00410	3.43e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_00412	7.17e-99	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
OPOHKMFD_00413	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OPOHKMFD_00414	5.26e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
OPOHKMFD_00415	1.2e-181	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
OPOHKMFD_00416	3.36e-184	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OPOHKMFD_00417	1.77e-32	yqzJ	-	-	-	-	-	-	-
OPOHKMFD_00418	2.72e-301	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OPOHKMFD_00419	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OPOHKMFD_00420	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OPOHKMFD_00421	7.66e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
OPOHKMFD_00422	3.86e-188	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OPOHKMFD_00423	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
OPOHKMFD_00424	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
OPOHKMFD_00425	6.84e-190	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OPOHKMFD_00426	1.62e-229	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
OPOHKMFD_00427	1.39e-184	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
OPOHKMFD_00428	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
OPOHKMFD_00429	2.69e-228	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
OPOHKMFD_00430	3.82e-95	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OPOHKMFD_00432	4.41e-284	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
OPOHKMFD_00434	1.46e-304	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OPOHKMFD_00435	3.23e-66	yqiX	-	-	S	-	-	-	YolD-like protein
OPOHKMFD_00436	5.46e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
OPOHKMFD_00437	3.71e-57	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
OPOHKMFD_00438	2.28e-248	yqkA	-	-	K	-	-	-	GrpB protein
OPOHKMFD_00439	1.25e-72	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
OPOHKMFD_00440	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
OPOHKMFD_00441	5.61e-221	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
OPOHKMFD_00442	6.61e-26	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
OPOHKMFD_00443	1.04e-214	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
OPOHKMFD_00444	8.21e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
OPOHKMFD_00445	4.07e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
OPOHKMFD_00446	1.19e-279	yqxK	-	-	L	-	-	-	DNA helicase
OPOHKMFD_00447	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_00448	7.23e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
OPOHKMFD_00449	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
OPOHKMFD_00450	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
OPOHKMFD_00451	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
OPOHKMFD_00452	7.27e-42	yqkK	-	-	-	-	-	-	-
OPOHKMFD_00453	2.78e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
OPOHKMFD_00454	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
OPOHKMFD_00455	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
OPOHKMFD_00456	1.86e-212	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
OPOHKMFD_00457	6.8e-294	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
OPOHKMFD_00458	1.39e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OPOHKMFD_00459	2.37e-271	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
OPOHKMFD_00460	3e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
OPOHKMFD_00461	1.37e-99	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
OPOHKMFD_00462	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OPOHKMFD_00463	1.15e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
OPOHKMFD_00464	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
OPOHKMFD_00465	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
OPOHKMFD_00466	6.02e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
OPOHKMFD_00467	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
OPOHKMFD_00468	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
OPOHKMFD_00469	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
OPOHKMFD_00470	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
OPOHKMFD_00471	8.93e-192	ypuA	-	-	S	-	-	-	Secreted protein
OPOHKMFD_00472	4.66e-41	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OPOHKMFD_00473	8.64e-97	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OPOHKMFD_00478	7.27e-26	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
OPOHKMFD_00480	7.72e-57	-	-	-	-	-	-	-	-
OPOHKMFD_00481	1.15e-302	-	-	-	I	-	-	-	Pfam Lipase (class 3)
OPOHKMFD_00482	8.22e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
OPOHKMFD_00484	3.29e-104	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
OPOHKMFD_00485	4.49e-136	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
OPOHKMFD_00489	1.87e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
OPOHKMFD_00490	1.73e-13	-	-	-	-	-	-	-	-
OPOHKMFD_00491	3.96e-84	-	-	-	O	-	-	-	Papain family cysteine protease
OPOHKMFD_00493	1.22e-29	-	-	-	L	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	DNA/RNA non-specific endonuclease
OPOHKMFD_00494	3.82e-37	-	-	-	-	-	-	-	-
OPOHKMFD_00496	8.28e-56	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OPOHKMFD_00498	6.74e-30	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
OPOHKMFD_00500	2.66e-122	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
OPOHKMFD_00501	5.98e-72	ypuD	-	-	-	-	-	-	-
OPOHKMFD_00502	1.39e-258	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OPOHKMFD_00503	2.5e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
OPOHKMFD_00504	2.1e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OPOHKMFD_00505	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
OPOHKMFD_00506	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OPOHKMFD_00507	1.7e-118	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
OPOHKMFD_00508	3.82e-167	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OPOHKMFD_00509	2e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OPOHKMFD_00510	2.92e-126	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
OPOHKMFD_00511	4.11e-273	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
OPOHKMFD_00512	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
OPOHKMFD_00513	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
OPOHKMFD_00514	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
OPOHKMFD_00515	1.5e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
OPOHKMFD_00516	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
OPOHKMFD_00517	4.67e-279	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
OPOHKMFD_00518	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPOHKMFD_00519	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OPOHKMFD_00520	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
OPOHKMFD_00521	2.7e-257	rsiX	-	-	-	-	-	-	-
OPOHKMFD_00522	2.89e-175	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
OPOHKMFD_00523	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OPOHKMFD_00524	3.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OPOHKMFD_00525	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
OPOHKMFD_00526	5.67e-258	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
OPOHKMFD_00527	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
OPOHKMFD_00528	6.13e-129	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
OPOHKMFD_00529	5.04e-148	ypbE	-	-	M	-	-	-	Lysin motif
OPOHKMFD_00530	1.42e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
OPOHKMFD_00531	4.33e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
OPOHKMFD_00532	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OPOHKMFD_00533	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
OPOHKMFD_00534	2.68e-226	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
OPOHKMFD_00535	1.02e-152	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
OPOHKMFD_00536	4.88e-208	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
OPOHKMFD_00537	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
OPOHKMFD_00538	2.68e-143	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
OPOHKMFD_00539	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
OPOHKMFD_00540	1.73e-147	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
OPOHKMFD_00541	9.5e-263	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
OPOHKMFD_00542	6.91e-237	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
OPOHKMFD_00543	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
OPOHKMFD_00544	2.73e-134	yphA	-	-	-	-	-	-	-
OPOHKMFD_00545	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
OPOHKMFD_00546	8.69e-40	ypzH	-	-	-	-	-	-	-
OPOHKMFD_00547	4.77e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
OPOHKMFD_00548	2.01e-243	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
OPOHKMFD_00549	7.09e-27	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
OPOHKMFD_00550	5.25e-177	yphF	-	-	-	-	-	-	-
OPOHKMFD_00551	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OPOHKMFD_00552	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OPOHKMFD_00553	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
OPOHKMFD_00554	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
OPOHKMFD_00555	8.72e-178	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
OPOHKMFD_00556	5.46e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
OPOHKMFD_00557	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
OPOHKMFD_00558	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
OPOHKMFD_00559	3.69e-183	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
OPOHKMFD_00560	1.44e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OPOHKMFD_00561	4.7e-262	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OPOHKMFD_00562	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
OPOHKMFD_00563	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OPOHKMFD_00564	8.47e-221	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OPOHKMFD_00565	4.18e-145	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
OPOHKMFD_00566	8.71e-148	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
OPOHKMFD_00567	1.81e-292	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
OPOHKMFD_00568	3.82e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
OPOHKMFD_00569	3.7e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OPOHKMFD_00570	1.21e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
OPOHKMFD_00571	1.64e-300	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
OPOHKMFD_00572	3.56e-297	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
OPOHKMFD_00573	1.83e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
OPOHKMFD_00574	5.55e-100	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
OPOHKMFD_00575	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
OPOHKMFD_00576	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
OPOHKMFD_00577	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
OPOHKMFD_00578	6.63e-125	ypjA	-	-	S	-	-	-	membrane
OPOHKMFD_00579	2.79e-182	ypjB	-	-	S	-	-	-	sporulation protein
OPOHKMFD_00580	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
OPOHKMFD_00581	1.01e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
OPOHKMFD_00582	9.78e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
OPOHKMFD_00583	2.52e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
OPOHKMFD_00584	6.34e-165	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
OPOHKMFD_00585	1.41e-266	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
OPOHKMFD_00586	3.04e-278	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
OPOHKMFD_00587	4.87e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
OPOHKMFD_00588	4.85e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
OPOHKMFD_00589	3.69e-198	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OPOHKMFD_00590	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OPOHKMFD_00591	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
OPOHKMFD_00592	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
OPOHKMFD_00593	2.66e-102	ypmB	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_00594	5.1e-284	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
OPOHKMFD_00595	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
OPOHKMFD_00596	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
OPOHKMFD_00597	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OPOHKMFD_00598	1.95e-119	ypoC	-	-	-	-	-	-	-
OPOHKMFD_00599	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
OPOHKMFD_00600	1.3e-149	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OPOHKMFD_00601	2.52e-238	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
OPOHKMFD_00604	1.42e-10	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
OPOHKMFD_00605	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
OPOHKMFD_00606	8.72e-68	yppG	-	-	S	-	-	-	YppG-like protein
OPOHKMFD_00607	1.02e-93	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
OPOHKMFD_00608	1.52e-109	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
OPOHKMFD_00609	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
OPOHKMFD_00610	1.39e-298	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
OPOHKMFD_00611	6.62e-126	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
OPOHKMFD_00612	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
OPOHKMFD_00613	1.16e-285	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
OPOHKMFD_00615	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
OPOHKMFD_00616	4.63e-176	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPOHKMFD_00617	8.48e-203	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OPOHKMFD_00618	7.8e-238	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
OPOHKMFD_00619	2.83e-237	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
OPOHKMFD_00620	1.2e-131	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
OPOHKMFD_00621	4.09e-224	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
OPOHKMFD_00622	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OPOHKMFD_00623	1.11e-126	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
OPOHKMFD_00624	1e-290	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
OPOHKMFD_00625	2.63e-265	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
OPOHKMFD_00626	9.54e-113	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
OPOHKMFD_00627	0.0	ypbR	-	-	S	-	-	-	Dynamin family
OPOHKMFD_00628	4.07e-52	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
OPOHKMFD_00629	1.08e-11	-	-	-	-	-	-	-	-
OPOHKMFD_00630	2.26e-213	ypcP	-	-	L	-	-	-	5'3' exonuclease
OPOHKMFD_00631	5.23e-05	-	-	-	-	ko:K06429	-	ko00000	-
OPOHKMFD_00632	1.6e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
OPOHKMFD_00633	8.02e-137	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OPOHKMFD_00634	2.31e-162	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
OPOHKMFD_00635	7.99e-41	ypeQ	-	-	S	-	-	-	Zinc-finger
OPOHKMFD_00636	1.23e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
OPOHKMFD_00637	1.17e-22	degR	-	-	-	-	-	-	-
OPOHKMFD_00638	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
OPOHKMFD_00639	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
OPOHKMFD_00640	6.09e-225	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OPOHKMFD_00641	3.66e-113	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
OPOHKMFD_00642	2.94e-141	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
OPOHKMFD_00643	8.11e-204	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
OPOHKMFD_00644	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
OPOHKMFD_00645	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
OPOHKMFD_00646	1.19e-184	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
OPOHKMFD_00647	1.41e-147	ypjP	-	-	S	-	-	-	YpjP-like protein
OPOHKMFD_00648	8.91e-121	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
OPOHKMFD_00649	7.88e-121	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OPOHKMFD_00650	2.24e-141	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OPOHKMFD_00651	8.03e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
OPOHKMFD_00652	1.4e-236	yplP	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_00653	1.04e-309	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OPOHKMFD_00654	2.12e-53	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
OPOHKMFD_00655	7.93e-140	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
OPOHKMFD_00656	1.82e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
OPOHKMFD_00657	1.95e-128	ypmS	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_00658	8.69e-40	ypmT	-	-	S	-	-	-	Uncharacterized ympT
OPOHKMFD_00659	9.99e-290	mepA	-	-	V	-	-	-	MATE efflux family protein
OPOHKMFD_00660	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
OPOHKMFD_00661	9.83e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OPOHKMFD_00662	4.13e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
OPOHKMFD_00663	1.66e-157	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
OPOHKMFD_00664	9.41e-279	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
OPOHKMFD_00665	2.69e-227	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
OPOHKMFD_00666	1.79e-82	cgeA	-	-	-	ko:K06319	-	ko00000	-
OPOHKMFD_00667	9.46e-29	cgeC	-	-	-	ko:K06321	-	ko00000	-
OPOHKMFD_00668	9.12e-13	cgeC	-	-	-	ko:K06321	-	ko00000	-
OPOHKMFD_00669	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
OPOHKMFD_00670	2.81e-184	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
OPOHKMFD_00671	3.85e-314	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OPOHKMFD_00672	2.3e-159	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OPOHKMFD_00673	3.85e-152	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OPOHKMFD_00674	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
OPOHKMFD_00675	5.27e-197	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
OPOHKMFD_00676	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
OPOHKMFD_00677	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
OPOHKMFD_00678	7.3e-50	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
OPOHKMFD_00679	7.44e-159	yodN	-	-	-	-	-	-	-
OPOHKMFD_00681	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
OPOHKMFD_00682	1.35e-136	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
OPOHKMFD_00683	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
OPOHKMFD_00684	2.08e-12	-	-	-	-	-	-	-	-
OPOHKMFD_00685	1.68e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
OPOHKMFD_00686	1.33e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
OPOHKMFD_00687	4.86e-41	yodI	-	-	-	-	-	-	-
OPOHKMFD_00688	1.24e-165	yodH	-	-	Q	-	-	-	Methyltransferase
OPOHKMFD_00689	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
OPOHKMFD_00690	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OPOHKMFD_00691	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
OPOHKMFD_00692	8.09e-215	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
OPOHKMFD_00693	1.31e-146	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
OPOHKMFD_00694	4.53e-139	yodC	-	-	C	-	-	-	nitroreductase
OPOHKMFD_00695	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
OPOHKMFD_00696	5.64e-84	iolK	-	-	S	-	-	-	tautomerase
OPOHKMFD_00697	1.31e-289	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
OPOHKMFD_00698	1.95e-14	-	-	-	-	-	-	-	-
OPOHKMFD_00699	8.34e-104	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
OPOHKMFD_00700	2.33e-207	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
OPOHKMFD_00701	1.52e-57	-	-	-	-	-	-	-	-
OPOHKMFD_00702	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
OPOHKMFD_00703	3.71e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
OPOHKMFD_00704	1.44e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OPOHKMFD_00705	1.69e-312	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
OPOHKMFD_00707	3.54e-140	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OPOHKMFD_00708	1.13e-293	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
OPOHKMFD_00709	1.3e-267	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
OPOHKMFD_00710	1.04e-141	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OPOHKMFD_00711	1.55e-206	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
OPOHKMFD_00712	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
OPOHKMFD_00713	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
OPOHKMFD_00714	2.59e-264	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
OPOHKMFD_00715	9.48e-214	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
OPOHKMFD_00716	4.35e-300	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OPOHKMFD_00717	3.91e-211	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
OPOHKMFD_00718	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
OPOHKMFD_00719	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
OPOHKMFD_00720	1.91e-42	yozC	-	-	-	-	-	-	-
OPOHKMFD_00721	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
OPOHKMFD_00722	1.83e-49	yocN	-	-	-	-	-	-	-
OPOHKMFD_00723	2.94e-55	yozN	-	-	-	-	-	-	-
OPOHKMFD_00724	2.69e-114	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
OPOHKMFD_00725	2.02e-43	-	-	-	-	-	-	-	-
OPOHKMFD_00726	3.02e-70	yocL	-	-	-	-	-	-	-
OPOHKMFD_00727	1.42e-107	yocK	-	-	T	-	-	-	general stress protein
OPOHKMFD_00728	5.95e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OPOHKMFD_00729	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
OPOHKMFD_00730	6.78e-174	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
OPOHKMFD_00731	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OPOHKMFD_00732	4.99e-252	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OPOHKMFD_00733	3.99e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
OPOHKMFD_00734	6.44e-239	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
OPOHKMFD_00735	1.32e-122	yocC	-	-	-	-	-	-	-
OPOHKMFD_00736	6.12e-184	-	-	-	-	-	-	-	-
OPOHKMFD_00737	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
OPOHKMFD_00738	9.39e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OPOHKMFD_00739	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
OPOHKMFD_00740	5.2e-121	yobW	-	-	-	-	-	-	-
OPOHKMFD_00741	1.37e-220	yobV	-	-	K	-	-	-	WYL domain
OPOHKMFD_00742	1.43e-110	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
OPOHKMFD_00743	4.49e-168	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
OPOHKMFD_00744	1.26e-126	yobS	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_00745	5.06e-181	-	-	-	J	-	-	-	FR47-like protein
OPOHKMFD_00746	2.39e-171	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
OPOHKMFD_00747	5.01e-69	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
OPOHKMFD_00748	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
OPOHKMFD_00749	2.75e-116	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
OPOHKMFD_00750	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
OPOHKMFD_00751	6.69e-112	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
OPOHKMFD_00752	1.66e-52	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
OPOHKMFD_00753	1.65e-127	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
OPOHKMFD_00754	1.76e-126	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
OPOHKMFD_00756	9.73e-49	-	-	-	-	-	-	-	-
OPOHKMFD_00758	9.74e-67	-	-	-	S	-	-	-	YolD-like protein
OPOHKMFD_00759	2.3e-294	-	-	-	S	-	-	-	damaged DNA binding
OPOHKMFD_00761	2.14e-17	-	-	-	Q	-	-	-	methyltransferase
OPOHKMFD_00762	4.01e-33	-	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
OPOHKMFD_00763	0.000751	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
OPOHKMFD_00764	3.91e-52	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OPOHKMFD_00766	1.57e-121	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
OPOHKMFD_00768	9.95e-23	-	-	-	-	-	-	-	-
OPOHKMFD_00769	3.23e-86	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
OPOHKMFD_00770	3.12e-98	-	-	-	-	-	-	-	-
OPOHKMFD_00772	3.46e-10	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
OPOHKMFD_00773	4.98e-106	yoaW	-	-	-	-	-	-	-
OPOHKMFD_00774	2.82e-36	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
OPOHKMFD_00775	6.23e-131	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
OPOHKMFD_00776	3.25e-67	ynaF	-	-	-	-	-	-	-
OPOHKMFD_00783	1.15e-22	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
OPOHKMFD_00784	1.38e-172	-	-	-	-	-	-	-	-
OPOHKMFD_00785	2.49e-43	yoaF	-	-	-	-	-	-	-
OPOHKMFD_00787	2.11e-49	-	-	-	S	-	-	-	TM2 domain
OPOHKMFD_00788	7.53e-157	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
OPOHKMFD_00789	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
OPOHKMFD_00792	1.11e-202	yoaV	-	-	EG	-	-	-	EamA-like transporter family
OPOHKMFD_00793	6.67e-203	yoaU	-	-	K	-	-	-	LysR substrate binding domain
OPOHKMFD_00794	1.34e-189	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
OPOHKMFD_00795	7.19e-41	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_00796	3.22e-98	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
OPOHKMFD_00797	1.04e-217	yoaR	-	-	V	-	-	-	vancomycin resistance protein
OPOHKMFD_00798	3.22e-114	-	-	-	-	-	-	-	-
OPOHKMFD_00799	1.49e-87	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
OPOHKMFD_00800	3.71e-185	yoaP	-	-	K	-	-	-	YoaP-like
OPOHKMFD_00802	4.23e-291	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
OPOHKMFD_00804	2.42e-169	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
OPOHKMFD_00805	5e-253	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
OPOHKMFD_00806	1.79e-145	yoaK	-	-	S	-	-	-	Membrane
OPOHKMFD_00807	2.61e-171	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
OPOHKMFD_00808	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
OPOHKMFD_00809	2.49e-286	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
OPOHKMFD_00810	2.46e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
OPOHKMFD_00811	1.46e-19	-	-	-	-	-	-	-	-
OPOHKMFD_00813	2.08e-44	yoaF	-	-	-	-	-	-	-
OPOHKMFD_00814	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OPOHKMFD_00815	5.57e-233	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OPOHKMFD_00816	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
OPOHKMFD_00817	1.11e-300	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
OPOHKMFD_00818	3.26e-113	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OPOHKMFD_00819	5.51e-168	yoxB	-	-	-	-	-	-	-
OPOHKMFD_00820	9.05e-52	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
OPOHKMFD_00821	6.25e-157	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
OPOHKMFD_00822	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
OPOHKMFD_00823	2.72e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OPOHKMFD_00824	3.86e-261	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OPOHKMFD_00825	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_00826	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
OPOHKMFD_00827	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
OPOHKMFD_00828	6.64e-234	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
OPOHKMFD_00829	3.99e-197	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_00830	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
OPOHKMFD_00831	1.92e-46	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
OPOHKMFD_00832	1.14e-124	-	-	-	L	-	-	-	Integrase
OPOHKMFD_00834	4.13e-127	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
OPOHKMFD_00835	1.33e-310	yoeA	-	-	V	-	-	-	MATE efflux family protein
OPOHKMFD_00836	9.53e-241	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
OPOHKMFD_00837	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
OPOHKMFD_00838	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OPOHKMFD_00839	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
OPOHKMFD_00840	2.12e-84	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
OPOHKMFD_00841	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
OPOHKMFD_00842	3.09e-267	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
OPOHKMFD_00843	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OPOHKMFD_00844	2.81e-316	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
OPOHKMFD_00845	8.37e-42	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
OPOHKMFD_00846	9.56e-212	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
OPOHKMFD_00847	6.03e-175	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
OPOHKMFD_00848	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OPOHKMFD_00849	7.39e-296	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
OPOHKMFD_00850	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
OPOHKMFD_00851	5.53e-210	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
OPOHKMFD_00852	9.97e-103	yngA	-	-	S	-	-	-	membrane
OPOHKMFD_00853	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
OPOHKMFD_00854	9.85e-317	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
OPOHKMFD_00856	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
OPOHKMFD_00857	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
OPOHKMFD_00858	8.74e-75	ynfC	-	-	-	-	-	-	-
OPOHKMFD_00859	7.45e-18	-	-	-	-	-	-	-	-
OPOHKMFD_00860	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OPOHKMFD_00861	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OPOHKMFD_00862	1.72e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
OPOHKMFD_00863	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
OPOHKMFD_00864	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
OPOHKMFD_00865	1.63e-71	yneQ	-	-	-	-	-	-	-
OPOHKMFD_00866	1.4e-95	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
OPOHKMFD_00867	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
OPOHKMFD_00869	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
OPOHKMFD_00870	4.37e-119	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OPOHKMFD_00871	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OPOHKMFD_00872	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
OPOHKMFD_00873	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
OPOHKMFD_00874	5.77e-85	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
OPOHKMFD_00875	3.97e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
OPOHKMFD_00876	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
OPOHKMFD_00877	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
OPOHKMFD_00878	1.68e-164	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
OPOHKMFD_00879	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
OPOHKMFD_00880	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
OPOHKMFD_00881	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
OPOHKMFD_00882	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OPOHKMFD_00883	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
OPOHKMFD_00884	2.29e-144	yneB	-	-	L	-	-	-	resolvase
OPOHKMFD_00885	2.44e-64	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
OPOHKMFD_00886	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OPOHKMFD_00887	2.47e-101	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
OPOHKMFD_00888	3.79e-96	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
OPOHKMFD_00889	2.57e-172	yndL	-	-	S	-	-	-	Replication protein
OPOHKMFD_00891	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
OPOHKMFD_00892	1.21e-149	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
OPOHKMFD_00893	1.2e-194	yndG	-	-	S	-	-	-	DoxX-like family
OPOHKMFD_00894	5.12e-285	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
OPOHKMFD_00895	9.26e-249	yndE7	-	-	U	ko:K06311	-	ko00000,ko02000	Spore germination
OPOHKMFD_00896	0.0	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
OPOHKMFD_00899	1.81e-103	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
OPOHKMFD_00900	1.04e-94	-	-	-	-	-	-	-	-
OPOHKMFD_00901	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
OPOHKMFD_00904	8.59e-170	-	-	-	S	-	-	-	Domain of unknown function, YrpD
OPOHKMFD_00906	1.12e-209	-	-	-	S	-	-	-	Thymidylate synthase
OPOHKMFD_00909	3.01e-102	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
OPOHKMFD_00910	9.48e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2691)
OPOHKMFD_00912	5.91e-279	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OPOHKMFD_00913	0.0	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
OPOHKMFD_00914	7.18e-145	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
OPOHKMFD_00915	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
OPOHKMFD_00916	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
OPOHKMFD_00917	5.23e-277	xylR	-	-	GK	-	-	-	ROK family
OPOHKMFD_00918	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
OPOHKMFD_00919	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
OPOHKMFD_00920	1.56e-103	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
OPOHKMFD_00921	9.53e-160	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
OPOHKMFD_00922	5.75e-124	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
OPOHKMFD_00923	6.63e-122	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
OPOHKMFD_00924	4.15e-49	-	-	-	-	-	-	-	-
OPOHKMFD_00925	2.44e-155	-	-	-	-	-	-	-	-
OPOHKMFD_00927	2.46e-13	-	-	-	-	-	-	-	-
OPOHKMFD_00928	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
OPOHKMFD_00929	1.16e-88	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
OPOHKMFD_00930	3.37e-310	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
OPOHKMFD_00931	1.82e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OPOHKMFD_00932	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
OPOHKMFD_00933	9.94e-151	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
OPOHKMFD_00934	2.24e-141	-	-	-	-	-	-	-	-
OPOHKMFD_00935	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OPOHKMFD_00936	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OPOHKMFD_00937	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
OPOHKMFD_00938	1.2e-30	ymzA	-	-	-	-	-	-	-
OPOHKMFD_00939	1.63e-31	-	-	-	-	-	-	-	-
OPOHKMFD_00940	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
OPOHKMFD_00941	1.38e-223	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OPOHKMFD_00942	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
OPOHKMFD_00944	2.02e-66	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
OPOHKMFD_00945	2.23e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
OPOHKMFD_00946	5.98e-105	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
OPOHKMFD_00947	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
OPOHKMFD_00949	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
OPOHKMFD_00950	2.67e-207	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
OPOHKMFD_00951	8.03e-81	ymzB	-	-	-	-	-	-	-
OPOHKMFD_00952	1.24e-135	pksA	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_00953	2.67e-125	ymcC	-	-	S	-	-	-	Membrane
OPOHKMFD_00955	1.91e-91	-	-	-	S	-	-	-	Regulatory protein YrvL
OPOHKMFD_00956	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OPOHKMFD_00957	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OPOHKMFD_00958	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
OPOHKMFD_00959	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
OPOHKMFD_00960	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OPOHKMFD_00961	1.89e-274	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OPOHKMFD_00962	8.31e-253	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
OPOHKMFD_00963	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
OPOHKMFD_00964	6.18e-195	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
OPOHKMFD_00965	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
OPOHKMFD_00966	1.82e-276	pbpX	-	-	V	-	-	-	Beta-lactamase
OPOHKMFD_00967	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OPOHKMFD_00968	3.71e-300	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
OPOHKMFD_00969	3.34e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OPOHKMFD_00970	8.75e-177	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
OPOHKMFD_00971	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
OPOHKMFD_00972	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
OPOHKMFD_00973	3.01e-166	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
OPOHKMFD_00974	3.37e-309	ymfH	-	-	S	-	-	-	zinc protease
OPOHKMFD_00975	4.5e-297	albE	-	-	S	-	-	-	Peptidase M16
OPOHKMFD_00976	5.1e-266	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
OPOHKMFD_00977	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_00978	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
OPOHKMFD_00979	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
OPOHKMFD_00980	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
OPOHKMFD_00981	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OPOHKMFD_00982	6.39e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OPOHKMFD_00983	4.9e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
OPOHKMFD_00984	5.56e-246	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OPOHKMFD_00985	8.17e-141	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
OPOHKMFD_00986	1.52e-207	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
OPOHKMFD_00987	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
OPOHKMFD_00988	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
OPOHKMFD_00989	2.4e-231	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
OPOHKMFD_00990	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
OPOHKMFD_00991	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OPOHKMFD_00992	2.22e-230	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
OPOHKMFD_00993	6.04e-220	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OPOHKMFD_00994	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OPOHKMFD_00995	1.11e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
OPOHKMFD_00996	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OPOHKMFD_00997	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
OPOHKMFD_00998	1.66e-56	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
OPOHKMFD_00999	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
OPOHKMFD_01000	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
OPOHKMFD_01001	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OPOHKMFD_01002	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
OPOHKMFD_01003	4.72e-285	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
OPOHKMFD_01004	1.39e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
OPOHKMFD_01005	5.77e-179	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
OPOHKMFD_01006	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OPOHKMFD_01007	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
OPOHKMFD_01008	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
OPOHKMFD_01009	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OPOHKMFD_01010	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
OPOHKMFD_01011	1.15e-99	ylxL	-	-	-	-	-	-	-
OPOHKMFD_01012	1.33e-175	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OPOHKMFD_01013	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
OPOHKMFD_01014	5.06e-144	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
OPOHKMFD_01015	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
OPOHKMFD_01016	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
OPOHKMFD_01017	1.81e-252	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
OPOHKMFD_01018	4.46e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
OPOHKMFD_01019	5.42e-254	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
OPOHKMFD_01020	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OPOHKMFD_01021	3.89e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OPOHKMFD_01022	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
OPOHKMFD_01023	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
OPOHKMFD_01024	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
OPOHKMFD_01025	7.87e-137	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
OPOHKMFD_01026	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
OPOHKMFD_01027	1.38e-253	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OPOHKMFD_01028	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OPOHKMFD_01029	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
OPOHKMFD_01030	1.09e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
OPOHKMFD_01031	2.81e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
OPOHKMFD_01032	2.61e-304	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
OPOHKMFD_01033	1.51e-78	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
OPOHKMFD_01034	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
OPOHKMFD_01035	1e-306	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
OPOHKMFD_01036	1.92e-144	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
OPOHKMFD_01037	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OPOHKMFD_01038	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
OPOHKMFD_01039	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
OPOHKMFD_01040	8.81e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
OPOHKMFD_01041	1.62e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
OPOHKMFD_01042	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OPOHKMFD_01043	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OPOHKMFD_01044	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OPOHKMFD_01045	1.13e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
OPOHKMFD_01046	2.59e-312	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OPOHKMFD_01047	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OPOHKMFD_01048	3.62e-215	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
OPOHKMFD_01049	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OPOHKMFD_01050	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
OPOHKMFD_01051	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
OPOHKMFD_01052	0.0	ylqG	-	-	-	-	-	-	-
OPOHKMFD_01053	5.83e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OPOHKMFD_01054	2.83e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OPOHKMFD_01055	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
OPOHKMFD_01056	2.41e-177	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
OPOHKMFD_01057	1.84e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OPOHKMFD_01058	9.77e-80	ylqD	-	-	S	-	-	-	YlqD protein
OPOHKMFD_01059	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
OPOHKMFD_01060	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
OPOHKMFD_01061	3.95e-308	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OPOHKMFD_01062	8.01e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OPOHKMFD_01063	1.67e-114	-	-	-	-	-	-	-	-
OPOHKMFD_01064	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
OPOHKMFD_01065	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
OPOHKMFD_01066	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
OPOHKMFD_01067	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OPOHKMFD_01068	3.5e-167	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
OPOHKMFD_01069	4.39e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
OPOHKMFD_01070	3.39e-229	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
OPOHKMFD_01071	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
OPOHKMFD_01072	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OPOHKMFD_01073	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
OPOHKMFD_01074	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
OPOHKMFD_01075	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
OPOHKMFD_01076	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_01077	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
OPOHKMFD_01078	8.13e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
OPOHKMFD_01079	9.44e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
OPOHKMFD_01080	4.57e-214	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
OPOHKMFD_01081	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
OPOHKMFD_01082	2.05e-179	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
OPOHKMFD_01083	3.07e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
OPOHKMFD_01084	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OPOHKMFD_01085	1.05e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OPOHKMFD_01086	4.8e-109	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OPOHKMFD_01087	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OPOHKMFD_01088	4.21e-285	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OPOHKMFD_01089	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
OPOHKMFD_01090	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
OPOHKMFD_01091	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
OPOHKMFD_01092	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
OPOHKMFD_01093	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
OPOHKMFD_01094	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
OPOHKMFD_01095	5.37e-107	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
OPOHKMFD_01096	5.05e-188	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
OPOHKMFD_01097	4.85e-184	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
OPOHKMFD_01098	1.59e-141	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
OPOHKMFD_01099	2.62e-285	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
OPOHKMFD_01100	1.41e-227	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
OPOHKMFD_01101	5.95e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
OPOHKMFD_01103	8.96e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OPOHKMFD_01104	2.67e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
OPOHKMFD_01105	2.46e-220	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
OPOHKMFD_01106	4.31e-182	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
OPOHKMFD_01107	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
OPOHKMFD_01108	1.31e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
OPOHKMFD_01109	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
OPOHKMFD_01110	2.97e-213	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
OPOHKMFD_01111	2.24e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
OPOHKMFD_01112	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OPOHKMFD_01113	8.3e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
OPOHKMFD_01114	2.71e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OPOHKMFD_01115	2.63e-82	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
OPOHKMFD_01116	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OPOHKMFD_01117	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
OPOHKMFD_01118	1.74e-177	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
OPOHKMFD_01119	1.22e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
OPOHKMFD_01120	1.28e-86	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
OPOHKMFD_01121	1.28e-161	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OPOHKMFD_01122	9.17e-204	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
OPOHKMFD_01123	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
OPOHKMFD_01124	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
OPOHKMFD_01125	1.83e-187	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
OPOHKMFD_01126	7.99e-180	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OPOHKMFD_01127	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OPOHKMFD_01128	2.05e-218	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
OPOHKMFD_01129	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
OPOHKMFD_01130	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OPOHKMFD_01131	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
OPOHKMFD_01132	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
OPOHKMFD_01133	1.5e-132	ylxX	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_01134	1.35e-143	ylxW	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_01135	3.37e-178	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
OPOHKMFD_01136	3.74e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
OPOHKMFD_01137	1.82e-255	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OPOHKMFD_01138	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
OPOHKMFD_01139	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OPOHKMFD_01140	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OPOHKMFD_01141	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OPOHKMFD_01142	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
OPOHKMFD_01143	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
OPOHKMFD_01144	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
OPOHKMFD_01145	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
OPOHKMFD_01146	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
OPOHKMFD_01147	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OPOHKMFD_01148	5.34e-213	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OPOHKMFD_01149	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
OPOHKMFD_01150	4.72e-107	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
OPOHKMFD_01151	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
OPOHKMFD_01152	6.94e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
OPOHKMFD_01154	7.11e-293	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
OPOHKMFD_01155	2.24e-238	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
OPOHKMFD_01156	2.56e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
OPOHKMFD_01157	9.11e-281	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
OPOHKMFD_01158	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OPOHKMFD_01159	6.07e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
OPOHKMFD_01160	4.36e-52	ylbG	-	-	S	-	-	-	UPF0298 protein
OPOHKMFD_01161	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
OPOHKMFD_01162	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
OPOHKMFD_01163	9.28e-89	ylbD	-	-	S	-	-	-	Putative coat protein
OPOHKMFD_01164	4.39e-256	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
OPOHKMFD_01165	1.08e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
OPOHKMFD_01166	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
OPOHKMFD_01167	1.21e-213	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
OPOHKMFD_01168	6.09e-70	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
OPOHKMFD_01169	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
OPOHKMFD_01170	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OPOHKMFD_01171	2.38e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
OPOHKMFD_01172	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OPOHKMFD_01173	2e-212	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
OPOHKMFD_01174	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OPOHKMFD_01175	2.57e-273	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
OPOHKMFD_01176	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
OPOHKMFD_01177	4.25e-220	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
OPOHKMFD_01178	9.32e-112	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OPOHKMFD_01179	3.76e-316	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
OPOHKMFD_01180	2.44e-126	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OPOHKMFD_01181	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_01182	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
OPOHKMFD_01183	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
OPOHKMFD_01184	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
OPOHKMFD_01185	1.74e-57	ylaE	-	-	-	-	-	-	-
OPOHKMFD_01187	3.56e-51	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
OPOHKMFD_01188	1.44e-56	ylaB	-	-	-	-	-	-	-
OPOHKMFD_01189	0.0	ylaA	-	-	-	-	-	-	-
OPOHKMFD_01190	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
OPOHKMFD_01191	1.28e-223	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OPOHKMFD_01192	1.48e-100	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
OPOHKMFD_01193	9.48e-195	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
OPOHKMFD_01194	4.48e-35	ykzI	-	-	-	-	-	-	-
OPOHKMFD_01195	1.25e-150	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
OPOHKMFD_01196	1.34e-56	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
OPOHKMFD_01197	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
OPOHKMFD_01198	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
OPOHKMFD_01199	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OPOHKMFD_01200	1.47e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OPOHKMFD_01201	3.52e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OPOHKMFD_01202	1.06e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OPOHKMFD_01203	6.82e-149	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
OPOHKMFD_01204	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
OPOHKMFD_01205	1.14e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OPOHKMFD_01206	4.79e-186	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
OPOHKMFD_01207	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
OPOHKMFD_01208	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OPOHKMFD_01209	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OPOHKMFD_01210	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
OPOHKMFD_01211	2.41e-198	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
OPOHKMFD_01212	2.65e-306	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
OPOHKMFD_01213	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
OPOHKMFD_01214	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
OPOHKMFD_01215	6.35e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
OPOHKMFD_01216	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
OPOHKMFD_01217	6.74e-214	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OPOHKMFD_01218	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OPOHKMFD_01219	5.43e-52	ykoA	-	-	-	-	-	-	-
OPOHKMFD_01220	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
OPOHKMFD_01221	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
OPOHKMFD_01222	4.07e-215	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
OPOHKMFD_01223	7.41e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_01224	1.11e-264	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
OPOHKMFD_01225	6.1e-160	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_01226	1.16e-233	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPOHKMFD_01227	5.97e-147	yknW	-	-	S	-	-	-	Yip1 domain
OPOHKMFD_01228	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
OPOHKMFD_01229	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
OPOHKMFD_01230	2.82e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OPOHKMFD_01231	6.61e-110	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
OPOHKMFD_01232	1.99e-121	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
OPOHKMFD_01233	4.29e-313	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
OPOHKMFD_01234	2.54e-243	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OPOHKMFD_01235	2.17e-140	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
OPOHKMFD_01236	3.3e-198	yknT	-	-	-	ko:K06437	-	ko00000	-
OPOHKMFD_01237	1.78e-120	rok	-	-	K	-	-	-	Repressor of ComK
OPOHKMFD_01238	6.01e-104	ykuV	-	-	CO	-	-	-	thiol-disulfide
OPOHKMFD_01239	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
OPOHKMFD_01240	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
OPOHKMFD_01241	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
OPOHKMFD_01242	1.27e-272	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
OPOHKMFD_01243	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
OPOHKMFD_01244	1.2e-100	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
OPOHKMFD_01245	1.18e-220	ykuO	-	-	-	-	-	-	-
OPOHKMFD_01246	1.44e-109	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
OPOHKMFD_01247	6.52e-216	ccpC	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_01248	5.15e-100	ykuL	-	-	S	-	-	-	CBS domain
OPOHKMFD_01249	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
OPOHKMFD_01250	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
OPOHKMFD_01251	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_01252	7.16e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
OPOHKMFD_01253	1.06e-181	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPOHKMFD_01254	3.48e-212	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
OPOHKMFD_01255	5.84e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_01256	3.62e-305	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
OPOHKMFD_01257	2.15e-109	ykyB	-	-	S	-	-	-	YkyB-like protein
OPOHKMFD_01258	4.95e-216	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
OPOHKMFD_01259	1.05e-22	-	-	-	-	-	-	-	-
OPOHKMFD_01260	3.44e-282	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
OPOHKMFD_01261	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OPOHKMFD_01262	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
OPOHKMFD_01263	1.04e-169	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
OPOHKMFD_01264	1.68e-17	vgb	-	-	H	ko:K18235	-	ko00000,ko01000,ko01504	Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
OPOHKMFD_01265	1.4e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
OPOHKMFD_01266	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
OPOHKMFD_01267	4.2e-160	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OPOHKMFD_01268	2.49e-256	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
OPOHKMFD_01269	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_01270	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OPOHKMFD_01271	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
OPOHKMFD_01272	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
OPOHKMFD_01273	6.87e-168	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
OPOHKMFD_01275	5.43e-229	ykvZ	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_01277	1.93e-264	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
OPOHKMFD_01278	3.99e-09	-	-	-	-	-	-	-	-
OPOHKMFD_01279	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
OPOHKMFD_01280	5.79e-117	stoA	-	-	CO	-	-	-	thiol-disulfide
OPOHKMFD_01281	9.18e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OPOHKMFD_01282	9.09e-142	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
OPOHKMFD_01283	2.5e-39	-	-	-	-	-	-	-	-
OPOHKMFD_01284	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_01285	2.67e-62	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
OPOHKMFD_01286	7.68e-172	ykvO	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
OPOHKMFD_01287	2.8e-81	ykvN	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_01288	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OPOHKMFD_01289	3.56e-179	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
OPOHKMFD_01290	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
OPOHKMFD_01291	6.42e-161	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OPOHKMFD_01292	3.35e-227	ykvI	-	-	S	-	-	-	membrane
OPOHKMFD_01293	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
OPOHKMFD_01294	1.65e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
OPOHKMFD_01295	4.91e-170	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
OPOHKMFD_01296	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
OPOHKMFD_01297	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
OPOHKMFD_01298	5.84e-95	eag	-	-	-	-	-	-	-
OPOHKMFD_01300	8.82e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
OPOHKMFD_01301	8.7e-123	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OPOHKMFD_01302	1.84e-146	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
OPOHKMFD_01303	1.77e-175	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
OPOHKMFD_01304	1.88e-292	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
OPOHKMFD_01305	2.29e-294	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
OPOHKMFD_01306	4.7e-192	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OPOHKMFD_01307	1.17e-291	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
OPOHKMFD_01308	3.8e-252	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OPOHKMFD_01310	4.58e-114	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OPOHKMFD_01311	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OPOHKMFD_01312	3.34e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
OPOHKMFD_01313	1.77e-28	ykzE	-	-	-	-	-	-	-
OPOHKMFD_01315	2.58e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
OPOHKMFD_01316	3.97e-199	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
OPOHKMFD_01317	1.55e-159	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
OPOHKMFD_01318	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
OPOHKMFD_01319	9.93e-200	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
OPOHKMFD_01320	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OPOHKMFD_01321	4.63e-227	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
OPOHKMFD_01322	1.71e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
OPOHKMFD_01323	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
OPOHKMFD_01324	5.94e-203	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OPOHKMFD_01325	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
OPOHKMFD_01326	1.35e-237	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
OPOHKMFD_01327	0.0	ykoS	-	-	-	-	-	-	-
OPOHKMFD_01328	2.42e-195	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
OPOHKMFD_01329	2.38e-127	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
OPOHKMFD_01330	3.68e-275	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
OPOHKMFD_01331	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
OPOHKMFD_01332	2.51e-35	ykoL	-	-	-	-	-	-	-
OPOHKMFD_01333	3.3e-25	-	-	-	-	-	-	-	-
OPOHKMFD_01334	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
OPOHKMFD_01335	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
OPOHKMFD_01337	1.45e-08	-	-	-	-	-	-	-	-
OPOHKMFD_01338	5.28e-111	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
OPOHKMFD_01339	9.6e-146	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
OPOHKMFD_01340	1.42e-305	ykoH	-	-	T	-	-	-	Histidine kinase
OPOHKMFD_01341	1.01e-157	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPOHKMFD_01342	3.73e-137	ykoF	-	-	S	-	-	-	YKOF-related Family
OPOHKMFD_01343	1.39e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
OPOHKMFD_01344	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_01345	7.36e-173	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
OPOHKMFD_01346	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OPOHKMFD_01347	8.62e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
OPOHKMFD_01348	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OPOHKMFD_01349	1.9e-113	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
OPOHKMFD_01350	8.15e-94	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
OPOHKMFD_01351	2.86e-97	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
OPOHKMFD_01352	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
OPOHKMFD_01353	1.32e-288	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OPOHKMFD_01354	4.3e-255	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OPOHKMFD_01355	1.66e-217	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
OPOHKMFD_01356	1.36e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
OPOHKMFD_01357	1.27e-72	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
OPOHKMFD_01358	2.43e-126	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OPOHKMFD_01359	6.42e-128	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
OPOHKMFD_01360	3.95e-167	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
OPOHKMFD_01361	2.11e-16	-	-	-	-	-	-	-	-
OPOHKMFD_01362	1.26e-287	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OPOHKMFD_01363	1.55e-119	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
OPOHKMFD_01364	1.78e-205	ykgA	-	-	E	-	-	-	Amidinotransferase
OPOHKMFD_01365	3.16e-258	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
OPOHKMFD_01366	2.82e-235	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
OPOHKMFD_01367	1.78e-210	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OPOHKMFD_01368	1.55e-253	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
OPOHKMFD_01369	2.64e-222	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
OPOHKMFD_01371	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
OPOHKMFD_01372	1.29e-234	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
OPOHKMFD_01373	3.02e-224	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OPOHKMFD_01374	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OPOHKMFD_01375	1.15e-195	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
OPOHKMFD_01376	3.2e-176	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
OPOHKMFD_01377	2.41e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OPOHKMFD_01379	2.21e-229	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
OPOHKMFD_01380	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OPOHKMFD_01382	1.9e-231	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
OPOHKMFD_01383	2.57e-309	steT	-	-	E	ko:K03294	-	ko00000	amino acid
OPOHKMFD_01384	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
OPOHKMFD_01385	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
OPOHKMFD_01386	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
OPOHKMFD_01387	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
OPOHKMFD_01388	5.76e-212	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
OPOHKMFD_01389	8.12e-53	xhlB	-	-	S	-	-	-	SPP1 phage holin
OPOHKMFD_01390	7.71e-52	xhlA	-	-	S	-	-	-	Haemolysin XhlA
OPOHKMFD_01391	6.16e-198	xepA	-	-	-	-	-	-	-
OPOHKMFD_01392	1.1e-31	xkdX	-	-	-	-	-	-	-
OPOHKMFD_01393	5.66e-70	xkdW	-	-	S	-	-	-	XkdW protein
OPOHKMFD_01394	0.0	-	-	-	-	-	-	-	-
OPOHKMFD_01395	4.43e-56	-	-	-	-	-	-	-	-
OPOHKMFD_01396	6.51e-134	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
OPOHKMFD_01397	1.26e-243	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
OPOHKMFD_01398	3.82e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
OPOHKMFD_01399	1.45e-51	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
OPOHKMFD_01400	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
OPOHKMFD_01401	4.25e-152	xkdP	-	-	S	-	-	-	Lysin motif
OPOHKMFD_01402	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
OPOHKMFD_01403	9.21e-99	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
OPOHKMFD_01404	6.01e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
OPOHKMFD_01405	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
OPOHKMFD_01406	2.87e-101	xkdJ	-	-	-	-	-	-	-
OPOHKMFD_01407	2.38e-114	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
OPOHKMFD_01408	2.91e-83	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
OPOHKMFD_01409	6.64e-82	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
OPOHKMFD_01410	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
OPOHKMFD_01411	1.4e-176	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
OPOHKMFD_01412	0.0	yqbA	-	-	S	-	-	-	portal protein
OPOHKMFD_01413	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
OPOHKMFD_01414	4.58e-177	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
OPOHKMFD_01415	8.12e-110	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OPOHKMFD_01419	7.48e-153	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
OPOHKMFD_01420	3.73e-203	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
OPOHKMFD_01422	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
OPOHKMFD_01423	1.53e-144	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
OPOHKMFD_01424	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
OPOHKMFD_01425	1.3e-137	yjqB	-	-	S	-	-	-	Pfam:DUF867
OPOHKMFD_01426	1.35e-80	yjqA	-	-	S	-	-	-	Bacterial PH domain
OPOHKMFD_01427	5.34e-218	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
OPOHKMFD_01428	1.79e-55	-	-	-	S	-	-	-	YCII-related domain
OPOHKMFD_01430	7.06e-271	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
OPOHKMFD_01431	1.23e-313	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
OPOHKMFD_01432	2.71e-103	yjoA	-	-	S	-	-	-	DinB family
OPOHKMFD_01433	1.31e-166	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
OPOHKMFD_01434	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
OPOHKMFD_01435	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
OPOHKMFD_01436	9.87e-238	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
OPOHKMFD_01437	3.93e-289	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
OPOHKMFD_01438	2.23e-195	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
OPOHKMFD_01439	1.08e-270	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
OPOHKMFD_01440	1.86e-245	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
OPOHKMFD_01441	4.91e-240	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
OPOHKMFD_01442	1.19e-311	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
OPOHKMFD_01443	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
OPOHKMFD_01444	2.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
OPOHKMFD_01445	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
OPOHKMFD_01446	2.36e-116	yjlB	-	-	S	-	-	-	Cupin domain
OPOHKMFD_01447	8.95e-225	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
OPOHKMFD_01448	2.79e-175	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
OPOHKMFD_01449	9.04e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
OPOHKMFD_01450	8.69e-189	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
OPOHKMFD_01451	1.11e-41	-	-	-	-	-	-	-	-
OPOHKMFD_01452	1.19e-277	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OPOHKMFD_01453	1.16e-286	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
OPOHKMFD_01455	1.45e-144	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
OPOHKMFD_01457	1.6e-122	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
OPOHKMFD_01458	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
OPOHKMFD_01459	4.96e-133	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
OPOHKMFD_01460	3.78e-45	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
OPOHKMFD_01461	4.5e-61	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
OPOHKMFD_01462	1.27e-133	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
OPOHKMFD_01463	1.13e-29	yjfB	-	-	S	-	-	-	Putative motility protein
OPOHKMFD_01464	8.68e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
OPOHKMFD_01465	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
OPOHKMFD_01467	5.08e-222	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OPOHKMFD_01468	2.31e-69	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
OPOHKMFD_01469	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
OPOHKMFD_01470	8.3e-105	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OPOHKMFD_01472	1.47e-116	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
OPOHKMFD_01473	7.58e-75	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
OPOHKMFD_01474	3.58e-240	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
OPOHKMFD_01475	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
OPOHKMFD_01476	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
OPOHKMFD_01477	8.47e-59	yjcN	-	-	-	-	-	-	-
OPOHKMFD_01478	2.59e-22	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
OPOHKMFD_01479	4.48e-23	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
OPOHKMFD_01480	2.49e-07	-	-	-	-	-	-	-	-
OPOHKMFD_01481	2.28e-25	-	-	-	-	-	-	-	-
OPOHKMFD_01482	1.92e-47	-	-	-	-	-	-	-	-
OPOHKMFD_01486	2.51e-19	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_01488	6.79e-11	-	-	-	S	-	-	-	Family of unknown function (DUF5316)
OPOHKMFD_01490	1.8e-87	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
OPOHKMFD_01491	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
OPOHKMFD_01492	4.49e-136	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
OPOHKMFD_01498	4.34e-94	-	-	-	S	-	-	-	peptidoglycan catabolic process
OPOHKMFD_01500	9.06e-82	-	-	-	-	-	-	-	-
OPOHKMFD_01502	2.3e-41	-	-	-	-	-	-	-	-
OPOHKMFD_01503	2.53e-23	-	-	-	-	-	-	-	-
OPOHKMFD_01508	2.21e-56	-	-	-	-	-	-	-	-
OPOHKMFD_01509	1.6e-309	-	-	-	I	-	-	-	Pfam Lipase (class 3)
OPOHKMFD_01510	2.11e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
OPOHKMFD_01511	3.64e-158	ynaC	-	-	-	-	-	-	-
OPOHKMFD_01512	8.25e-61	-	-	-	S	-	-	-	Restriction endonuclease
OPOHKMFD_01513	3.17e-32	-	-	-	-	-	-	-	-
OPOHKMFD_01514	1.14e-20	-	-	-	S	-	-	-	peptidoglycan catabolic process
OPOHKMFD_01515	5.35e-61	-	-	-	K	-	-	-	Helix-turn-helix domain
OPOHKMFD_01516	8.18e-07	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
OPOHKMFD_01517	3.71e-96	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
OPOHKMFD_01518	7.5e-80	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
OPOHKMFD_01519	1.38e-66	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
OPOHKMFD_01520	4.17e-103	-	-	-	-	-	-	-	-
OPOHKMFD_01521	3.77e-12	-	-	-	S	-	-	-	Helix-turn-helix domain
OPOHKMFD_01522	4.52e-21	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
OPOHKMFD_01523	6.49e-58	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
OPOHKMFD_01526	2.47e-272	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
OPOHKMFD_01527	1.68e-126	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
OPOHKMFD_01528	1.84e-280	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
OPOHKMFD_01529	8.05e-273	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
OPOHKMFD_01530	1.63e-178	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
OPOHKMFD_01531	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
OPOHKMFD_01532	7.75e-94	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OPOHKMFD_01533	6.31e-51	-	-	-	-	-	-	-	-
OPOHKMFD_01534	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
OPOHKMFD_01535	1.88e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
OPOHKMFD_01538	1.23e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
OPOHKMFD_01539	1.44e-72	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
OPOHKMFD_01540	1.08e-54	cotW	-	-	-	ko:K06341	-	ko00000	-
OPOHKMFD_01541	3.55e-110	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
OPOHKMFD_01542	6.3e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
OPOHKMFD_01543	4.57e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
OPOHKMFD_01544	1.71e-102	yjbX	-	-	S	-	-	-	Spore coat protein
OPOHKMFD_01545	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
OPOHKMFD_01546	4.85e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
OPOHKMFD_01547	1.52e-238	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OPOHKMFD_01548	6.78e-174	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
OPOHKMFD_01549	2.18e-41	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
OPOHKMFD_01550	1.33e-276	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
OPOHKMFD_01551	2.32e-138	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
OPOHKMFD_01552	5.7e-177	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OPOHKMFD_01553	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
OPOHKMFD_01554	6.65e-180	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
OPOHKMFD_01555	4.28e-202	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
OPOHKMFD_01556	4.17e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OPOHKMFD_01557	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
OPOHKMFD_01558	1.87e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
OPOHKMFD_01559	7.32e-130	yjbK	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_01560	4.85e-127	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OPOHKMFD_01561	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
OPOHKMFD_01562	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
OPOHKMFD_01563	2.68e-28	-	-	-	-	-	-	-	-
OPOHKMFD_01564	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
OPOHKMFD_01565	4.7e-277	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
OPOHKMFD_01566	4.65e-149	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OPOHKMFD_01567	7.1e-144	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
OPOHKMFD_01568	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
OPOHKMFD_01569	8.88e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OPOHKMFD_01570	3.35e-260	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
OPOHKMFD_01571	1.27e-219	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
OPOHKMFD_01572	1.12e-248	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
OPOHKMFD_01573	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OPOHKMFD_01574	3.44e-211	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OPOHKMFD_01575	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
OPOHKMFD_01576	6.15e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
OPOHKMFD_01577	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
OPOHKMFD_01578	4.25e-197	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OPOHKMFD_01579	6.73e-216	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OPOHKMFD_01580	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
OPOHKMFD_01581	1.99e-235	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
OPOHKMFD_01582	2.5e-233	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
OPOHKMFD_01583	3.17e-191	yjaZ	-	-	O	-	-	-	Zn-dependent protease
OPOHKMFD_01584	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OPOHKMFD_01585	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OPOHKMFD_01586	3.48e-33	yjzB	-	-	-	-	-	-	-
OPOHKMFD_01587	1.07e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
OPOHKMFD_01588	3.7e-234	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
OPOHKMFD_01589	5.84e-129	yjaV	-	-	-	-	-	-	-
OPOHKMFD_01590	2.42e-182	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
OPOHKMFD_01591	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
OPOHKMFD_01592	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
OPOHKMFD_01593	2.88e-223	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OPOHKMFD_01594	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
OPOHKMFD_01595	8.11e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
OPOHKMFD_01596	3.27e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
OPOHKMFD_01597	1.27e-175	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
OPOHKMFD_01598	6.08e-294	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OPOHKMFD_01599	8.29e-252	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OPOHKMFD_01600	1.32e-113	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
OPOHKMFD_01601	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
OPOHKMFD_01602	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
OPOHKMFD_01603	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
OPOHKMFD_01604	5.05e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
OPOHKMFD_01605	1.52e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
OPOHKMFD_01606	1.01e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
OPOHKMFD_01607	7.97e-93	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
OPOHKMFD_01608	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
OPOHKMFD_01609	6.16e-200	yitS	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_01610	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
OPOHKMFD_01611	5.37e-58	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
OPOHKMFD_01612	5.02e-119	-	-	-	-	-	-	-	-
OPOHKMFD_01613	2.08e-77	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
OPOHKMFD_01614	3.29e-127	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
OPOHKMFD_01615	4.76e-217	-	-	-	-	-	-	-	-
OPOHKMFD_01616	4.16e-122	-	-	-	-	-	-	-	-
OPOHKMFD_01617	2.75e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
OPOHKMFD_01618	1.75e-76	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
OPOHKMFD_01619	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
OPOHKMFD_01620	8.44e-91	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
OPOHKMFD_01621	2.39e-192	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
OPOHKMFD_01622	8.28e-291	yitG	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
OPOHKMFD_01623	6.13e-283	yitF	5.5.1.27	-	M	ko:K18983	ko00053,map00053	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
OPOHKMFD_01624	6.77e-145	yitE	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OPOHKMFD_01625	4.31e-180	yitD	4.4.1.19	-	S	ko:K08097	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	synthase
OPOHKMFD_01626	3.84e-162	-	3.1.3.71	-	H	ko:K05979	ko00680,ko01120,map00680,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the ComB family
OPOHKMFD_01627	9.51e-185	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
OPOHKMFD_01628	1.37e-295	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
OPOHKMFD_01629	4.06e-145	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
OPOHKMFD_01630	2.25e-199	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OPOHKMFD_01631	2.15e-96	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
OPOHKMFD_01632	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OPOHKMFD_01633	5.19e-138	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
OPOHKMFD_01634	1.72e-120	yisT	-	-	S	-	-	-	DinB family
OPOHKMFD_01635	1.73e-247	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
OPOHKMFD_01636	3.04e-234	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
OPOHKMFD_01637	1.41e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_01638	2.91e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
OPOHKMFD_01639	8.91e-189	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
OPOHKMFD_01640	1.07e-114	yizA	-	-	S	-	-	-	Damage-inducible protein DinB
OPOHKMFD_01641	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
OPOHKMFD_01642	2.49e-130	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
OPOHKMFD_01643	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
OPOHKMFD_01644	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
OPOHKMFD_01645	2.66e-219	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
OPOHKMFD_01646	2.11e-219	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
OPOHKMFD_01647	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
OPOHKMFD_01648	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
OPOHKMFD_01649	1.76e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
OPOHKMFD_01650	3.34e-92	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
OPOHKMFD_01651	1.49e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
OPOHKMFD_01652	4.58e-85	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
OPOHKMFD_01653	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
OPOHKMFD_01654	1.84e-64	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
OPOHKMFD_01655	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
OPOHKMFD_01656	1.4e-280	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
OPOHKMFD_01657	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
OPOHKMFD_01658	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
OPOHKMFD_01659	8.94e-100	yhjR	-	-	S	-	-	-	Rubrerythrin
OPOHKMFD_01660	3.54e-77	yhjQ	-	-	C	-	-	-	COG1145 Ferredoxin
OPOHKMFD_01661	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
OPOHKMFD_01662	9.56e-268	-	-	-	EGP	-	-	-	Transmembrane secretion effector
OPOHKMFD_01663	2.5e-259	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
OPOHKMFD_01664	2.07e-237	yhjM	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_01665	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
OPOHKMFD_01666	1.07e-204	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
OPOHKMFD_01667	1.14e-256	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
OPOHKMFD_01668	1.49e-270	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
OPOHKMFD_01671	4.01e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
OPOHKMFD_01672	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
OPOHKMFD_01673	1.79e-117	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
OPOHKMFD_01674	4.87e-141	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
OPOHKMFD_01675	4.13e-78	yhjD	-	-	-	-	-	-	-
OPOHKMFD_01676	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
OPOHKMFD_01677	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OPOHKMFD_01678	2.04e-56	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
OPOHKMFD_01679	1.04e-215	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
OPOHKMFD_01680	6.29e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
OPOHKMFD_01681	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
OPOHKMFD_01682	2.24e-203	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPOHKMFD_01683	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
OPOHKMFD_01684	1.85e-260	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
OPOHKMFD_01685	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
OPOHKMFD_01686	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
OPOHKMFD_01687	1.39e-255	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
OPOHKMFD_01688	1.95e-140	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
OPOHKMFD_01689	6.52e-222	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
OPOHKMFD_01690	1.97e-231	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
OPOHKMFD_01691	1.47e-100	-	-	-	K	-	-	-	acetyltransferase
OPOHKMFD_01692	6.91e-260	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
OPOHKMFD_01693	1.08e-304	yhfN	-	-	O	-	-	-	Peptidase M48
OPOHKMFD_01694	2.28e-84	yhfM	-	-	-	-	-	-	-
OPOHKMFD_01695	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
OPOHKMFD_01696	2.48e-142	yhfK	-	-	GM	-	-	-	NmrA-like family
OPOHKMFD_01697	3.34e-244	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
OPOHKMFD_01698	5.93e-183	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
OPOHKMFD_01699	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OPOHKMFD_01700	1.53e-93	-	-	-	S	-	-	-	ASCH
OPOHKMFD_01701	1.55e-252	yhfE	-	-	G	-	-	-	peptidase M42
OPOHKMFD_01703	3.8e-177	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
OPOHKMFD_01704	8.77e-237	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OPOHKMFD_01705	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
OPOHKMFD_01706	5.79e-132	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_01707	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OPOHKMFD_01708	3.99e-230	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
OPOHKMFD_01709	1.29e-259	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OPOHKMFD_01710	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
OPOHKMFD_01711	1.31e-118	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
OPOHKMFD_01712	2.72e-44	-	-	-	C	-	-	-	Rubrerythrin
OPOHKMFD_01713	7.73e-312	yhfA	-	-	C	-	-	-	membrane
OPOHKMFD_01714	6.27e-291	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
OPOHKMFD_01715	7.62e-157	ecsC	-	-	S	-	-	-	EcsC protein family
OPOHKMFD_01716	2.55e-271	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
OPOHKMFD_01717	1.28e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
OPOHKMFD_01718	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
OPOHKMFD_01719	2.15e-261	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OPOHKMFD_01720	6.32e-104	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
OPOHKMFD_01721	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
OPOHKMFD_01722	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
OPOHKMFD_01723	8.48e-73	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
OPOHKMFD_01724	3.3e-115	yhaK	-	-	S	-	-	-	Putative zincin peptidase
OPOHKMFD_01725	2.33e-161	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OPOHKMFD_01726	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
OPOHKMFD_01727	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
OPOHKMFD_01728	0.0	yhaN	-	-	L	-	-	-	AAA domain
OPOHKMFD_01729	9.44e-301	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
OPOHKMFD_01730	5.14e-272	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
OPOHKMFD_01731	4.57e-214	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_01732	9.36e-36	-	-	-	S	-	-	-	YhzD-like protein
OPOHKMFD_01733	1.79e-169	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
OPOHKMFD_01735	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
OPOHKMFD_01736	1.85e-267	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
OPOHKMFD_01737	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
OPOHKMFD_01738	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
OPOHKMFD_01739	1.29e-261	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
OPOHKMFD_01740	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
OPOHKMFD_01741	7.19e-260	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
OPOHKMFD_01742	1.32e-273	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
OPOHKMFD_01743	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
OPOHKMFD_01744	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
OPOHKMFD_01745	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
OPOHKMFD_01746	1.29e-140	yheG	-	-	GM	-	-	-	NAD(P)H-binding
OPOHKMFD_01747	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
OPOHKMFD_01748	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
OPOHKMFD_01749	3.6e-107	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
OPOHKMFD_01750	8.11e-300	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
OPOHKMFD_01751	9.07e-197	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
OPOHKMFD_01752	1.18e-192	nodB1	-	-	G	-	-	-	deacetylase
OPOHKMFD_01753	2.7e-176	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
OPOHKMFD_01754	1.06e-258	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
OPOHKMFD_01755	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
OPOHKMFD_01756	1.05e-171	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
OPOHKMFD_01757	1.38e-85	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OPOHKMFD_01758	2.48e-66	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OPOHKMFD_01759	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
OPOHKMFD_01760	5.1e-284	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
OPOHKMFD_01761	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
OPOHKMFD_01762	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
OPOHKMFD_01763	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OPOHKMFD_01764	2.74e-243	yhdN	-	-	C	-	-	-	Aldo keto reductase
OPOHKMFD_01765	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
OPOHKMFD_01766	6.13e-258	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
OPOHKMFD_01767	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
OPOHKMFD_01768	1.75e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OPOHKMFD_01769	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OPOHKMFD_01770	5e-309	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OPOHKMFD_01771	3.58e-316	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
OPOHKMFD_01772	1.84e-204	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPOHKMFD_01773	1.19e-257	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
OPOHKMFD_01774	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_01775	1.45e-203	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
OPOHKMFD_01776	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
OPOHKMFD_01777	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
OPOHKMFD_01778	5.29e-307	ygxB	-	-	M	-	-	-	Conserved TM helix
OPOHKMFD_01779	1.37e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
OPOHKMFD_01780	4.84e-275	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
OPOHKMFD_01781	1.02e-71	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
OPOHKMFD_01782	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
OPOHKMFD_01783	1.1e-114	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
OPOHKMFD_01784	5.44e-144	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OPOHKMFD_01785	8.92e-271	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
OPOHKMFD_01786	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
OPOHKMFD_01787	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OPOHKMFD_01788	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OPOHKMFD_01789	5.7e-196	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
OPOHKMFD_01790	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OPOHKMFD_01791	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OPOHKMFD_01792	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OPOHKMFD_01793	2.5e-154	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
OPOHKMFD_01794	1.76e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
OPOHKMFD_01795	4.27e-89	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
OPOHKMFD_01796	4.78e-218	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
OPOHKMFD_01797	5.1e-134	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
OPOHKMFD_01798	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
OPOHKMFD_01799	1.68e-146	yhcQ	-	-	M	-	-	-	Spore coat protein
OPOHKMFD_01800	1.09e-224	yhcP	-	-	-	-	-	-	-
OPOHKMFD_01801	3.47e-103	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OPOHKMFD_01802	3.63e-60	yhcM	-	-	-	-	-	-	-
OPOHKMFD_01803	3.22e-65	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
OPOHKMFD_01804	1.69e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
OPOHKMFD_01805	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OPOHKMFD_01806	3.36e-249	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
OPOHKMFD_01807	8.24e-173	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
OPOHKMFD_01808	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
OPOHKMFD_01809	1.99e-211	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OPOHKMFD_01810	3.59e-210	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_01811	3.24e-156	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_01812	1.67e-79	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_01813	4.14e-69	-	-	-	-	-	-	-	-
OPOHKMFD_01814	3.95e-59	yhcC	-	-	-	-	-	-	-
OPOHKMFD_01815	4.87e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
OPOHKMFD_01816	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
OPOHKMFD_01817	2.67e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
OPOHKMFD_01818	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
OPOHKMFD_01819	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
OPOHKMFD_01820	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
OPOHKMFD_01821	4.28e-105	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
OPOHKMFD_01822	2.66e-95	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
OPOHKMFD_01823	3.4e-143	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
OPOHKMFD_01824	6.53e-113	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
OPOHKMFD_01825	2.77e-225	yhbB	-	-	S	-	-	-	Putative amidase domain
OPOHKMFD_01826	1.2e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OPOHKMFD_01827	6.43e-146	yhzB	-	-	S	-	-	-	B3/4 domain
OPOHKMFD_01829	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_01830	5.19e-98	ygaO	-	-	-	-	-	-	-
OPOHKMFD_01831	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OPOHKMFD_01833	9.35e-276	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
OPOHKMFD_01834	8.33e-190	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OPOHKMFD_01835	8.45e-218	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
OPOHKMFD_01836	9.01e-179	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
OPOHKMFD_01837	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
OPOHKMFD_01839	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OPOHKMFD_01840	3.56e-166	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
OPOHKMFD_01841	1.58e-36	-	-	-	-	-	-	-	-
OPOHKMFD_01842	6.37e-185	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
OPOHKMFD_01859	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
OPOHKMFD_01860	1.64e-120	-	-	-	M	-	-	-	FR47-like protein
OPOHKMFD_01861	4.54e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
OPOHKMFD_01862	1.68e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
OPOHKMFD_01863	1.95e-109	yuaE	-	-	S	-	-	-	DinB superfamily
OPOHKMFD_01864	5.8e-137	yuaD	-	-	-	-	-	-	-
OPOHKMFD_01865	4.26e-292	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
OPOHKMFD_01866	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
OPOHKMFD_01867	3.53e-123	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
OPOHKMFD_01868	5.83e-118	yuaB	-	-	-	-	-	-	-
OPOHKMFD_01869	1.83e-157	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
OPOHKMFD_01870	1.85e-301	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
OPOHKMFD_01871	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
OPOHKMFD_01872	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OPOHKMFD_01873	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
OPOHKMFD_01874	6.82e-114	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
OPOHKMFD_01876	6.02e-183	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
OPOHKMFD_01877	3.8e-256	yubA	-	-	S	-	-	-	transporter activity
OPOHKMFD_01878	3.05e-234	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
OPOHKMFD_01879	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
OPOHKMFD_01880	2.86e-72	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
OPOHKMFD_01881	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
OPOHKMFD_01882	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
OPOHKMFD_01883	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
OPOHKMFD_01884	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
OPOHKMFD_01885	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
OPOHKMFD_01886	1.2e-297	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
OPOHKMFD_01887	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
OPOHKMFD_01888	2.41e-178	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
OPOHKMFD_01889	3.52e-48	-	-	-	-	-	-	-	-
OPOHKMFD_01890	3.63e-95	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
OPOHKMFD_01891	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
OPOHKMFD_01892	5.09e-300	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
OPOHKMFD_01893	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
OPOHKMFD_01894	6.2e-48	-	-	-	-	-	-	-	-
OPOHKMFD_01895	5.01e-69	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
OPOHKMFD_01896	2.92e-232	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
OPOHKMFD_01897	4.22e-95	yugN	-	-	S	-	-	-	YugN-like family
OPOHKMFD_01899	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
OPOHKMFD_01900	5.56e-291	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
OPOHKMFD_01901	2.85e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
OPOHKMFD_01902	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
OPOHKMFD_01903	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
OPOHKMFD_01904	5.43e-255	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
OPOHKMFD_01905	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_01906	9.89e-201	yugF	-	-	I	-	-	-	Hydrolase
OPOHKMFD_01907	8.84e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
OPOHKMFD_01908	4.53e-284	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
OPOHKMFD_01909	1.51e-296	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OPOHKMFD_01910	2.49e-91	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
OPOHKMFD_01911	1.71e-149	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
OPOHKMFD_01913	4.61e-244	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
OPOHKMFD_01914	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
OPOHKMFD_01915	1.92e-97	yuxK	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_01916	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
OPOHKMFD_01917	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
OPOHKMFD_01918	3.26e-162	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
OPOHKMFD_01919	6.34e-254	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
OPOHKMFD_01920	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_01921	1.29e-236	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
OPOHKMFD_01922	6.97e-215	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
OPOHKMFD_01923	7.99e-309	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
OPOHKMFD_01924	1.73e-22	-	-	-	-	-	-	-	-
OPOHKMFD_01925	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
OPOHKMFD_01926	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OPOHKMFD_01927	1.72e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OPOHKMFD_01928	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OPOHKMFD_01929	2.12e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OPOHKMFD_01930	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OPOHKMFD_01931	5.97e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
OPOHKMFD_01932	7.81e-83	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
OPOHKMFD_01933	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OPOHKMFD_01934	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OPOHKMFD_01936	7.01e-183	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
OPOHKMFD_01937	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
OPOHKMFD_01938	4.38e-09	yuzC	-	-	-	-	-	-	-
OPOHKMFD_01939	2.92e-298	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
OPOHKMFD_01940	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OPOHKMFD_01941	2.69e-133	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
OPOHKMFD_01942	3.11e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
OPOHKMFD_01943	1.63e-52	yueH	-	-	S	-	-	-	YueH-like protein
OPOHKMFD_01944	1.19e-41	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
OPOHKMFD_01945	1.35e-244	yueF	-	-	S	-	-	-	transporter activity
OPOHKMFD_01946	6.59e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
OPOHKMFD_01947	8.4e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
OPOHKMFD_01948	1.91e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
OPOHKMFD_01949	3.53e-170	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPOHKMFD_01950	1.78e-96	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
OPOHKMFD_01951	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
OPOHKMFD_01952	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
OPOHKMFD_01953	2.47e-270	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
OPOHKMFD_01954	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
OPOHKMFD_01955	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
OPOHKMFD_01956	5.72e-290	yukF	-	-	QT	-	-	-	Transcriptional regulator
OPOHKMFD_01957	1.64e-261	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
OPOHKMFD_01958	1.2e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
OPOHKMFD_01959	2.02e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
OPOHKMFD_01960	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OPOHKMFD_01961	4.47e-228	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
OPOHKMFD_01962	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
OPOHKMFD_01963	2.1e-290	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
OPOHKMFD_01964	4.1e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
OPOHKMFD_01965	1.27e-212	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
OPOHKMFD_01966	2.36e-157	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
OPOHKMFD_01967	8.33e-125	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
OPOHKMFD_01968	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
OPOHKMFD_01969	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OPOHKMFD_01970	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
OPOHKMFD_01971	4.29e-149	yuiC	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_01972	9.78e-47	yuiB	-	-	S	-	-	-	Putative membrane protein
OPOHKMFD_01973	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
OPOHKMFD_01974	1.16e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
OPOHKMFD_01976	3.7e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OPOHKMFD_01977	2.84e-149	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
OPOHKMFD_01978	1.39e-115	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OPOHKMFD_01979	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
OPOHKMFD_01980	2.25e-207	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OPOHKMFD_01981	6.25e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OPOHKMFD_01982	3.51e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
OPOHKMFD_01983	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
OPOHKMFD_01984	2.7e-74	yuzD	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_01985	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
OPOHKMFD_01986	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
OPOHKMFD_01987	2.57e-221	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
OPOHKMFD_01988	1.14e-251	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OPOHKMFD_01989	6.79e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
OPOHKMFD_01990	4.63e-255	yutH	-	-	S	-	-	-	Spore coat protein
OPOHKMFD_01991	2.26e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
OPOHKMFD_01992	3.69e-183	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OPOHKMFD_01993	2.38e-99	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
OPOHKMFD_01994	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_01995	2.71e-144	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OPOHKMFD_01996	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OPOHKMFD_01997	2.66e-252	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
OPOHKMFD_01998	3.49e-169	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
OPOHKMFD_01999	8.06e-64	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
OPOHKMFD_02000	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
OPOHKMFD_02001	1.86e-180	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
OPOHKMFD_02002	7.07e-219	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
OPOHKMFD_02003	5.95e-77	yunG	-	-	-	-	-	-	-
OPOHKMFD_02004	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
OPOHKMFD_02005	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
OPOHKMFD_02006	6.93e-299	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
OPOHKMFD_02007	1.84e-282	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
OPOHKMFD_02008	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
OPOHKMFD_02009	1.47e-72	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
OPOHKMFD_02010	2.95e-123	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
OPOHKMFD_02011	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
OPOHKMFD_02012	4.27e-188	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
OPOHKMFD_02013	7.22e-142	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
OPOHKMFD_02014	4.85e-232	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OPOHKMFD_02015	5.74e-304	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
OPOHKMFD_02016	3.96e-293	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
OPOHKMFD_02017	4.42e-216	bsn	-	-	L	-	-	-	Ribonuclease
OPOHKMFD_02018	2.95e-263	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
OPOHKMFD_02019	8.71e-175	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
OPOHKMFD_02020	7.86e-208	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
OPOHKMFD_02021	1.94e-216	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
OPOHKMFD_02022	1.44e-198	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
OPOHKMFD_02023	9.59e-306	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
OPOHKMFD_02024	5.27e-235	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
OPOHKMFD_02025	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
OPOHKMFD_02026	4.87e-260	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
OPOHKMFD_02028	3.35e-56	-	-	-	-	-	-	-	-
OPOHKMFD_02029	5.06e-86	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OPOHKMFD_02030	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
OPOHKMFD_02031	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
OPOHKMFD_02032	1.14e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OPOHKMFD_02033	3.53e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
OPOHKMFD_02034	4.46e-182	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
OPOHKMFD_02035	1.56e-80	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OPOHKMFD_02036	8.33e-189	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
OPOHKMFD_02037	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
OPOHKMFD_02038	3.05e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OPOHKMFD_02039	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
OPOHKMFD_02040	8.14e-73	yusE	-	-	CO	-	-	-	Thioredoxin
OPOHKMFD_02041	7.62e-97	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
OPOHKMFD_02042	7.34e-54	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
OPOHKMFD_02043	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
OPOHKMFD_02044	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
OPOHKMFD_02045	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
OPOHKMFD_02046	1.34e-278	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
OPOHKMFD_02047	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
OPOHKMFD_02048	1.11e-13	-	-	-	S	-	-	-	YuzL-like protein
OPOHKMFD_02049	6.98e-211	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
OPOHKMFD_02050	4.51e-54	-	-	-	-	-	-	-	-
OPOHKMFD_02051	8.66e-70	yusN	-	-	M	-	-	-	Coat F domain
OPOHKMFD_02052	6.35e-98	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
OPOHKMFD_02053	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
OPOHKMFD_02054	1.7e-84	yusQ	-	-	S	-	-	-	Tautomerase enzyme
OPOHKMFD_02055	4.97e-138	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
OPOHKMFD_02056	8.42e-204	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
OPOHKMFD_02057	3.01e-63	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
OPOHKMFD_02058	2.51e-195	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
OPOHKMFD_02059	3.48e-88	-	-	-	S	-	-	-	YusW-like protein
OPOHKMFD_02060	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
OPOHKMFD_02061	7.45e-195	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
OPOHKMFD_02062	2.15e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
OPOHKMFD_02063	1.12e-304	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OPOHKMFD_02064	2.23e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPOHKMFD_02065	2.77e-316	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OPOHKMFD_02066	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_02067	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
OPOHKMFD_02068	2.6e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
OPOHKMFD_02069	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
OPOHKMFD_02070	4.6e-250	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
OPOHKMFD_02071	2.01e-248	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
OPOHKMFD_02072	9.39e-141	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OPOHKMFD_02073	9.56e-245	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OPOHKMFD_02074	7.65e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
OPOHKMFD_02075	2.48e-166	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
OPOHKMFD_02076	2.44e-143	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
OPOHKMFD_02077	6.17e-82	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
OPOHKMFD_02078	6.23e-286	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
OPOHKMFD_02079	1.2e-129	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
OPOHKMFD_02080	7.08e-307	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
OPOHKMFD_02081	1.56e-235	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPOHKMFD_02082	2.98e-218	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
OPOHKMFD_02083	1.23e-180	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
OPOHKMFD_02084	1.32e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
OPOHKMFD_02085	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
OPOHKMFD_02086	1.1e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPOHKMFD_02087	5.07e-32	-	-	-	-	-	-	-	-
OPOHKMFD_02088	6.74e-126	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
OPOHKMFD_02089	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
OPOHKMFD_02090	4.39e-290	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
OPOHKMFD_02091	8.13e-85	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
OPOHKMFD_02092	3.36e-272	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
OPOHKMFD_02093	3.82e-158	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_02094	3.61e-231	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
OPOHKMFD_02095	2.92e-191	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
OPOHKMFD_02096	3.76e-223	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPOHKMFD_02097	2e-235	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPOHKMFD_02098	4.45e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
OPOHKMFD_02100	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
OPOHKMFD_02101	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
OPOHKMFD_02102	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
OPOHKMFD_02103	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
OPOHKMFD_02104	4.21e-213	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
OPOHKMFD_02105	4.25e-175	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
OPOHKMFD_02106	2.89e-152	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
OPOHKMFD_02107	6.19e-201	yvgN	-	-	S	-	-	-	reductase
OPOHKMFD_02108	7.97e-113	yvgO	-	-	-	-	-	-	-
OPOHKMFD_02109	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
OPOHKMFD_02110	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
OPOHKMFD_02111	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OPOHKMFD_02112	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
OPOHKMFD_02114	2.34e-139	yvgT	-	-	S	-	-	-	membrane
OPOHKMFD_02115	1.99e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
OPOHKMFD_02116	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
OPOHKMFD_02117	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
OPOHKMFD_02118	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
OPOHKMFD_02119	3.02e-40	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
OPOHKMFD_02120	4.67e-63	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
OPOHKMFD_02121	5.71e-247	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
OPOHKMFD_02122	2.08e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OPOHKMFD_02123	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
OPOHKMFD_02124	3.73e-25	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
OPOHKMFD_02125	2.38e-69	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
OPOHKMFD_02126	5.77e-127	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
OPOHKMFD_02127	2.01e-140	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
OPOHKMFD_02128	1.07e-29	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
OPOHKMFD_02129	4.89e-22	-	-	-	-	-	-	-	-
OPOHKMFD_02132	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OPOHKMFD_02133	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
OPOHKMFD_02134	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
OPOHKMFD_02135	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
OPOHKMFD_02136	8.14e-196	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
OPOHKMFD_02137	4.9e-48	yvzC	-	-	K	-	-	-	transcriptional
OPOHKMFD_02138	4.08e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
OPOHKMFD_02139	9.82e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
OPOHKMFD_02140	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
OPOHKMFD_02141	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
OPOHKMFD_02142	2.54e-195	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
OPOHKMFD_02143	1.41e-135	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
OPOHKMFD_02144	1.49e-103	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
OPOHKMFD_02145	1.67e-110	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
OPOHKMFD_02146	7.1e-131	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_02149	1.18e-97	spaC1	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lanthionine synthetase C-like protein
OPOHKMFD_02150	8.57e-193	-	-	-	V	ko:K06147,ko:K06148,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
OPOHKMFD_02151	1.04e-231	bsaB	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lantibiotic dehydratase, C terminus
OPOHKMFD_02152	2.48e-134	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
OPOHKMFD_02153	2.27e-218	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OPOHKMFD_02154	1.55e-142	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
OPOHKMFD_02155	2.02e-268	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OPOHKMFD_02156	6.63e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
OPOHKMFD_02157	5.59e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
OPOHKMFD_02158	7.4e-223	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OPOHKMFD_02159	5.63e-145	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
OPOHKMFD_02160	5.58e-270	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OPOHKMFD_02161	8.29e-129	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
OPOHKMFD_02162	9.68e-136	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
OPOHKMFD_02163	2.96e-145	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
OPOHKMFD_02164	1.13e-156	yvbI	-	-	M	-	-	-	Membrane
OPOHKMFD_02165	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
OPOHKMFD_02166	9.77e-106	yvbK	-	-	K	-	-	-	acetyltransferase
OPOHKMFD_02167	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OPOHKMFD_02168	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
OPOHKMFD_02169	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
OPOHKMFD_02170	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
OPOHKMFD_02171	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OPOHKMFD_02172	2.42e-237	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OPOHKMFD_02173	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
OPOHKMFD_02174	1.51e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
OPOHKMFD_02175	1.21e-244	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OPOHKMFD_02176	4.9e-206	yvbU	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_02177	1.6e-197	yvbV	-	-	EG	-	-	-	EamA-like transporter family
OPOHKMFD_02178	7.07e-307	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
OPOHKMFD_02179	7.05e-248	-	-	-	S	-	-	-	Glycosyl hydrolase
OPOHKMFD_02180	8.37e-172	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OPOHKMFD_02181	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
OPOHKMFD_02182	9.08e-175	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OPOHKMFD_02183	4.36e-136	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OPOHKMFD_02184	1.8e-250	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OPOHKMFD_02185	2.04e-170	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
OPOHKMFD_02186	1.5e-202	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
OPOHKMFD_02188	2.08e-200	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
OPOHKMFD_02189	2.51e-264	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
OPOHKMFD_02190	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
OPOHKMFD_02191	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
OPOHKMFD_02192	3.82e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
OPOHKMFD_02193	5.29e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
OPOHKMFD_02194	4.62e-292	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
OPOHKMFD_02195	2.33e-235	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_02196	2.79e-145	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
OPOHKMFD_02197	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
OPOHKMFD_02198	6.75e-304	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
OPOHKMFD_02199	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
OPOHKMFD_02200	1.1e-233	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
OPOHKMFD_02201	1.76e-277	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
OPOHKMFD_02202	1.22e-82	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
OPOHKMFD_02203	9.14e-139	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OPOHKMFD_02204	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OPOHKMFD_02205	6.76e-246	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
OPOHKMFD_02206	7.76e-259	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
OPOHKMFD_02207	6.04e-249	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
OPOHKMFD_02208	8.82e-265	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
OPOHKMFD_02209	4.67e-280	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
OPOHKMFD_02210	1.25e-201	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
OPOHKMFD_02211	7.45e-280	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
OPOHKMFD_02212	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
OPOHKMFD_02213	7.94e-150	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
OPOHKMFD_02214	1.61e-157	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
OPOHKMFD_02215	1.24e-98	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
OPOHKMFD_02216	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
OPOHKMFD_02218	5.4e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
OPOHKMFD_02219	1.75e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
OPOHKMFD_02220	2.06e-161	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
OPOHKMFD_02221	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
OPOHKMFD_02222	7.19e-86	-	-	-	-	-	-	-	-
OPOHKMFD_02223	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
OPOHKMFD_02224	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
OPOHKMFD_02225	0.0	ybeC	-	-	E	-	-	-	amino acid
OPOHKMFD_02226	1.17e-137	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_02227	6.31e-68	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
OPOHKMFD_02228	1.03e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
OPOHKMFD_02229	5.53e-122	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
OPOHKMFD_02231	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
OPOHKMFD_02232	2.17e-146	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
OPOHKMFD_02233	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
OPOHKMFD_02234	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
OPOHKMFD_02235	5.26e-202	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
OPOHKMFD_02236	6.84e-190	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
OPOHKMFD_02237	3.37e-308	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
OPOHKMFD_02238	4.02e-300	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
OPOHKMFD_02239	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
OPOHKMFD_02240	1.54e-221	yvdE	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_02241	6.28e-136	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
OPOHKMFD_02242	7.84e-71	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
OPOHKMFD_02243	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
OPOHKMFD_02244	8.79e-136	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
OPOHKMFD_02245	2.7e-233	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OPOHKMFD_02246	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
OPOHKMFD_02247	4.46e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_02248	9.29e-250	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
OPOHKMFD_02249	3.84e-171	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPOHKMFD_02250	7.95e-45	-	-	-	-	-	-	-	-
OPOHKMFD_02251	8.02e-183	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
OPOHKMFD_02252	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
OPOHKMFD_02253	1.04e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
OPOHKMFD_02254	3.19e-225	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
OPOHKMFD_02255	8.53e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
OPOHKMFD_02256	2.39e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
OPOHKMFD_02257	1.18e-225	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
OPOHKMFD_02258	1.08e-184	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
OPOHKMFD_02259	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
OPOHKMFD_02260	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
OPOHKMFD_02262	0.0	-	-	-	-	-	-	-	-
OPOHKMFD_02263	2.8e-27	-	-	-	-	-	-	-	-
OPOHKMFD_02264	1.06e-110	-	-	-	-	-	-	-	-
OPOHKMFD_02265	2e-72	-	-	-	-	-	-	-	-
OPOHKMFD_02266	1.34e-75	-	-	-	-	-	-	-	-
OPOHKMFD_02267	7.95e-116	-	-	-	S	-	-	-	Predicted membrane protein (DUF2339)
OPOHKMFD_02268	6.37e-142	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
OPOHKMFD_02269	2.29e-175	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
OPOHKMFD_02270	7.64e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OPOHKMFD_02271	8.08e-147	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OPOHKMFD_02272	4.96e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
OPOHKMFD_02273	7.38e-292	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OPOHKMFD_02274	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
OPOHKMFD_02275	9.84e-281	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OPOHKMFD_02276	2.14e-179	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
OPOHKMFD_02277	1.05e-151	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
OPOHKMFD_02278	5.94e-118	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
OPOHKMFD_02279	3.05e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
OPOHKMFD_02280	2.06e-208	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
OPOHKMFD_02281	2.61e-194	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OPOHKMFD_02282	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OPOHKMFD_02283	9.81e-279	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OPOHKMFD_02284	1.95e-162	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OPOHKMFD_02285	3.02e-171	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
OPOHKMFD_02286	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
OPOHKMFD_02287	4.13e-104	yvnA	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
OPOHKMFD_02288	9.32e-293	cypX	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
OPOHKMFD_02289	2.49e-177	yvmC	2.3.2.22	-	S	ko:K17485	-	ko00000,ko01000	Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
OPOHKMFD_02290	1.03e-112	yvmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
OPOHKMFD_02291	4.26e-272	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
OPOHKMFD_02292	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
OPOHKMFD_02293	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
OPOHKMFD_02294	5.54e-219	yvlB	-	-	S	-	-	-	Putative adhesin
OPOHKMFD_02295	8.09e-65	yvlA	-	-	-	-	-	-	-
OPOHKMFD_02296	2.25e-45	yvkN	-	-	-	-	-	-	-
OPOHKMFD_02297	1.68e-157	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OPOHKMFD_02298	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
OPOHKMFD_02299	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
OPOHKMFD_02300	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_02301	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
OPOHKMFD_02302	1.43e-131	yvkB	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_02303	7.12e-294	yvkA	-	-	P	-	-	-	-transporter
OPOHKMFD_02304	1.83e-279	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OPOHKMFD_02305	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
OPOHKMFD_02306	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
OPOHKMFD_02307	1.56e-198	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
OPOHKMFD_02308	3.03e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
OPOHKMFD_02309	5.37e-74	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
OPOHKMFD_02310	7.58e-184	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
OPOHKMFD_02311	2.33e-231	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OPOHKMFD_02312	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OPOHKMFD_02313	2.02e-131	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OPOHKMFD_02314	2.46e-67	-	-	-	-	-	-	-	-
OPOHKMFD_02315	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
OPOHKMFD_02316	1.48e-90	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
OPOHKMFD_02317	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OPOHKMFD_02318	3.03e-74	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
OPOHKMFD_02319	2.16e-157	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OPOHKMFD_02320	1.05e-40	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OPOHKMFD_02321	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OPOHKMFD_02322	6.92e-92	yviE	-	-	-	-	-	-	-
OPOHKMFD_02323	7.66e-197	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
OPOHKMFD_02324	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
OPOHKMFD_02325	7.06e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
OPOHKMFD_02326	8.72e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
OPOHKMFD_02327	1.06e-95	yvyF	-	-	S	-	-	-	flagellar protein
OPOHKMFD_02328	2.26e-162	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
OPOHKMFD_02329	1.26e-61	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
OPOHKMFD_02330	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OPOHKMFD_02331	2.51e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_02332	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OPOHKMFD_02333	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
OPOHKMFD_02334	1.94e-136	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
OPOHKMFD_02335	1.23e-151	-	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_02339	2.9e-50	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
OPOHKMFD_02342	6.05e-100	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_02344	2.1e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
OPOHKMFD_02345	7.67e-293	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
OPOHKMFD_02346	1.61e-175	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
OPOHKMFD_02347	9.78e-136	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
OPOHKMFD_02348	9.1e-315	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
OPOHKMFD_02349	2.01e-302	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OPOHKMFD_02350	4.27e-257	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
OPOHKMFD_02351	1.28e-300	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OPOHKMFD_02352	2.13e-150	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OPOHKMFD_02353	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
OPOHKMFD_02354	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
OPOHKMFD_02355	1.39e-15	-	-	-	-	-	-	-	-
OPOHKMFD_02356	2.52e-40	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
OPOHKMFD_02357	4.48e-22	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
OPOHKMFD_02358	2.43e-264	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
OPOHKMFD_02359	1.64e-204	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
OPOHKMFD_02360	1.74e-13	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
OPOHKMFD_02361	2.7e-204	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
OPOHKMFD_02362	3.02e-171	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
OPOHKMFD_02365	0.0	tagF2	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
OPOHKMFD_02366	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OPOHKMFD_02367	2.4e-90	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
OPOHKMFD_02368	5.03e-183	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
OPOHKMFD_02369	1.5e-257	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OPOHKMFD_02370	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OPOHKMFD_02371	4.34e-237	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
OPOHKMFD_02372	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
OPOHKMFD_02373	1.48e-248	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
OPOHKMFD_02374	1.03e-262	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
OPOHKMFD_02375	1.06e-313	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
OPOHKMFD_02376	1.67e-176	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_02377	3.3e-201	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
OPOHKMFD_02378	5.14e-304	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OPOHKMFD_02379	2.29e-29	ywtC	-	-	-	-	-	-	-
OPOHKMFD_02380	1.1e-276	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
OPOHKMFD_02381	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
OPOHKMFD_02382	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
OPOHKMFD_02383	2.68e-227	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
OPOHKMFD_02384	6.18e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OPOHKMFD_02385	6.55e-84	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
OPOHKMFD_02386	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
OPOHKMFD_02387	7.87e-202	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
OPOHKMFD_02388	1.56e-204	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
OPOHKMFD_02389	2.05e-121	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
OPOHKMFD_02390	9.2e-64	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
OPOHKMFD_02391	8.76e-126	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
OPOHKMFD_02392	1.84e-187	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
OPOHKMFD_02393	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
OPOHKMFD_02394	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
OPOHKMFD_02395	1.68e-281	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OPOHKMFD_02396	9.09e-164	ywrJ	-	-	-	-	-	-	-
OPOHKMFD_02397	1.44e-196	cotB	-	-	-	ko:K06325	-	ko00000	-
OPOHKMFD_02398	1.2e-264	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
OPOHKMFD_02399	1.03e-17	-	-	-	-	-	-	-	-
OPOHKMFD_02400	4.35e-143	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OPOHKMFD_02401	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
OPOHKMFD_02402	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
OPOHKMFD_02403	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
OPOHKMFD_02404	6.44e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
OPOHKMFD_02405	6.07e-114	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
OPOHKMFD_02407	3.68e-130	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
OPOHKMFD_02408	2.34e-209	-	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_02409	4.92e-154	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
OPOHKMFD_02410	1.15e-67	-	-	-	-	-	-	-	-
OPOHKMFD_02411	4.03e-10	-	-	-	-	-	-	-	-
OPOHKMFD_02413	4.61e-66	-	-	-	-	-	-	-	-
OPOHKMFD_02414	1.01e-61	-	-	-	-	-	-	-	-
OPOHKMFD_02415	2.05e-312	ywqJ	-	-	S	-	-	-	Pre-toxin TG
OPOHKMFD_02416	2.17e-52	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
OPOHKMFD_02418	4.19e-196	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
OPOHKMFD_02419	4.66e-313	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OPOHKMFD_02420	5.87e-179	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
OPOHKMFD_02421	1.06e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
OPOHKMFD_02422	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
OPOHKMFD_02423	3.6e-25	-	-	-	-	-	-	-	-
OPOHKMFD_02424	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
OPOHKMFD_02425	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
OPOHKMFD_02426	1.45e-199	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
OPOHKMFD_02427	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
OPOHKMFD_02428	8.53e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
OPOHKMFD_02429	1.24e-86	ywpG	-	-	-	-	-	-	-
OPOHKMFD_02430	8.81e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
OPOHKMFD_02431	4.46e-66	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
OPOHKMFD_02432	3.42e-188	ywpD	-	-	T	-	-	-	Histidine kinase
OPOHKMFD_02433	1.61e-77	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
OPOHKMFD_02434	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
OPOHKMFD_02435	3.02e-254	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
OPOHKMFD_02436	2.37e-181	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
OPOHKMFD_02437	8.4e-171	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
OPOHKMFD_02438	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
OPOHKMFD_02439	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
OPOHKMFD_02440	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
OPOHKMFD_02441	5.56e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
OPOHKMFD_02442	2.79e-310	ywoF	-	-	P	-	-	-	Right handed beta helix region
OPOHKMFD_02443	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
OPOHKMFD_02444	5.39e-307	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
OPOHKMFD_02445	2.56e-134	yjgF	-	-	Q	-	-	-	Isochorismatase family
OPOHKMFD_02446	2.5e-101	-	-	-	-	-	-	-	-
OPOHKMFD_02447	2.27e-288	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
OPOHKMFD_02448	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
OPOHKMFD_02449	6.02e-135	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
OPOHKMFD_02450	4.49e-93	ywnJ	-	-	S	-	-	-	VanZ like family
OPOHKMFD_02451	2.63e-161	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
OPOHKMFD_02452	3.65e-115	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
OPOHKMFD_02453	6.95e-21	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
OPOHKMFD_02454	4.73e-234	-	-	-	M	-	-	-	NeuB family
OPOHKMFD_02455	7.07e-92	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
OPOHKMFD_02456	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OPOHKMFD_02457	4.46e-180	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
OPOHKMFD_02458	1.24e-77	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
OPOHKMFD_02459	1.69e-144	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
OPOHKMFD_02460	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_02461	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
OPOHKMFD_02462	3.2e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
OPOHKMFD_02463	8.2e-68	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
OPOHKMFD_02464	5.51e-28	-	-	-	E	ko:K11963	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
OPOHKMFD_02465	1.11e-21	csbD	-	-	K	-	-	-	CsbD-like
OPOHKMFD_02466	7.7e-110	ywmF	-	-	S	-	-	-	Peptidase M50
OPOHKMFD_02468	3.1e-129	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
OPOHKMFD_02469	1.08e-245	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OPOHKMFD_02470	3.69e-186	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OPOHKMFD_02472	1.44e-155	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
OPOHKMFD_02473	1.89e-157	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
OPOHKMFD_02474	9.77e-234	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
OPOHKMFD_02475	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OPOHKMFD_02476	8.01e-173	ywmB	-	-	S	-	-	-	TATA-box binding
OPOHKMFD_02477	4.54e-45	ywzB	-	-	S	-	-	-	membrane
OPOHKMFD_02478	1.76e-114	ywmA	-	-	-	-	-	-	-
OPOHKMFD_02479	2.44e-75	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
OPOHKMFD_02480	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OPOHKMFD_02481	4.46e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OPOHKMFD_02482	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OPOHKMFD_02483	7.94e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OPOHKMFD_02484	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OPOHKMFD_02485	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OPOHKMFD_02486	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
OPOHKMFD_02487	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
OPOHKMFD_02488	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OPOHKMFD_02489	5.09e-302	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OPOHKMFD_02490	2.49e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
OPOHKMFD_02491	2.35e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
OPOHKMFD_02492	1.58e-100	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OPOHKMFD_02493	4.56e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
OPOHKMFD_02494	3e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
OPOHKMFD_02495	1.04e-99	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
OPOHKMFD_02496	1.14e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
OPOHKMFD_02497	5.61e-73	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
OPOHKMFD_02499	2.42e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
OPOHKMFD_02500	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OPOHKMFD_02501	1.19e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OPOHKMFD_02502	2.93e-108	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
OPOHKMFD_02503	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
OPOHKMFD_02504	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
OPOHKMFD_02505	9.96e-135	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
OPOHKMFD_02506	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
OPOHKMFD_02507	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OPOHKMFD_02508	2.03e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
OPOHKMFD_02509	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OPOHKMFD_02510	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OPOHKMFD_02511	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
OPOHKMFD_02512	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
OPOHKMFD_02513	3.86e-119	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
OPOHKMFD_02514	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
OPOHKMFD_02515	1.03e-82	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
OPOHKMFD_02516	2.98e-269	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
OPOHKMFD_02517	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
OPOHKMFD_02518	6.46e-285	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
OPOHKMFD_02519	5.7e-235	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
OPOHKMFD_02520	1.32e-57	ywjC	-	-	-	-	-	-	-
OPOHKMFD_02521	1.35e-124	ywjB	-	-	H	-	-	-	RibD C-terminal domain
OPOHKMFD_02522	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
OPOHKMFD_02523	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OPOHKMFD_02524	1.02e-159	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
OPOHKMFD_02525	1.13e-121	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
OPOHKMFD_02526	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
OPOHKMFD_02527	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OPOHKMFD_02528	8.67e-111	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
OPOHKMFD_02529	1.62e-18	ywiC	-	-	S	-	-	-	YwiC-like protein
OPOHKMFD_02530	3.27e-168	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
OPOHKMFD_02531	1.2e-273	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
OPOHKMFD_02532	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
OPOHKMFD_02533	4.64e-96	ywiB	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_02534	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
OPOHKMFD_02535	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
OPOHKMFD_02537	3.53e-168	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
OPOHKMFD_02538	3.42e-297	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
OPOHKMFD_02539	1.7e-276	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
OPOHKMFD_02540	1.09e-313	-	-	-	L	-	-	-	Peptidase, M16
OPOHKMFD_02542	3.67e-272	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
OPOHKMFD_02543	9.28e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
OPOHKMFD_02545	1.09e-32	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
OPOHKMFD_02546	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
OPOHKMFD_02547	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OPOHKMFD_02548	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
OPOHKMFD_02549	2.1e-64	-	-	-	-	-	-	-	-
OPOHKMFD_02550	5.51e-123	ywhD	-	-	S	-	-	-	YwhD family
OPOHKMFD_02551	3.29e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
OPOHKMFD_02552	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
OPOHKMFD_02553	1.45e-93	ywhA	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_02554	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OPOHKMFD_02556	3.73e-301	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
OPOHKMFD_02557	7.42e-102	yffB	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_02558	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
OPOHKMFD_02559	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
OPOHKMFD_02560	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
OPOHKMFD_02561	5.39e-145	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
OPOHKMFD_02562	3.8e-196	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
OPOHKMFD_02563	1.77e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
OPOHKMFD_02564	3.73e-209	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_02565	1.37e-223	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
OPOHKMFD_02566	3.43e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
OPOHKMFD_02567	2.37e-176	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
OPOHKMFD_02568	2.21e-297	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
OPOHKMFD_02569	3.74e-266	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
OPOHKMFD_02570	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
OPOHKMFD_02571	3.14e-178	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPOHKMFD_02572	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
OPOHKMFD_02573	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
OPOHKMFD_02574	4.44e-274	ywfA	-	-	EGP	-	-	-	-transporter
OPOHKMFD_02575	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
OPOHKMFD_02576	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
OPOHKMFD_02577	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
OPOHKMFD_02578	6.05e-310	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
OPOHKMFD_02579	1.51e-100	-	-	-	-	-	-	-	-
OPOHKMFD_02580	9.16e-114	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
OPOHKMFD_02581	2.44e-206	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
OPOHKMFD_02582	9.08e-234	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
OPOHKMFD_02583	6.13e-177	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OPOHKMFD_02584	5.26e-236	spsG	-	-	M	-	-	-	Spore Coat
OPOHKMFD_02585	1.23e-164	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
OPOHKMFD_02586	2.27e-270	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
OPOHKMFD_02587	4.22e-210	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
OPOHKMFD_02588	3.73e-284	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
OPOHKMFD_02589	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
OPOHKMFD_02590	8.08e-187	spsA	-	-	M	-	-	-	Spore Coat
OPOHKMFD_02591	3.62e-112	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
OPOHKMFD_02592	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
OPOHKMFD_02593	1.86e-303	ywdJ	-	-	F	-	-	-	Xanthine uracil
OPOHKMFD_02594	2.18e-63	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
OPOHKMFD_02595	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
OPOHKMFD_02596	9.47e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OPOHKMFD_02597	3.84e-191	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
OPOHKMFD_02598	6.07e-185	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
OPOHKMFD_02599	6.19e-39	ywdA	-	-	-	-	-	-	-
OPOHKMFD_02600	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
OPOHKMFD_02601	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
OPOHKMFD_02602	2.91e-180	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
OPOHKMFD_02603	1.29e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
OPOHKMFD_02605	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
OPOHKMFD_02606	4.19e-239	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OPOHKMFD_02607	1.98e-179	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
OPOHKMFD_02608	1.26e-268	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
OPOHKMFD_02609	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
OPOHKMFD_02610	1.12e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
OPOHKMFD_02611	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
OPOHKMFD_02612	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OPOHKMFD_02613	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
OPOHKMFD_02614	5.11e-49	ydaS	-	-	S	-	-	-	membrane
OPOHKMFD_02615	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
OPOHKMFD_02616	2.96e-286	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OPOHKMFD_02617	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
OPOHKMFD_02618	3.42e-158	ywcC	-	-	K	-	-	-	transcriptional regulator
OPOHKMFD_02620	8.67e-64	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
OPOHKMFD_02621	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OPOHKMFD_02622	2.09e-143	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
OPOHKMFD_02623	1.47e-306	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
OPOHKMFD_02624	1.4e-245	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
OPOHKMFD_02625	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
OPOHKMFD_02626	1.09e-149	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
OPOHKMFD_02627	3.25e-185	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OPOHKMFD_02628	2.7e-203	ywbI	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_02629	1.1e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
OPOHKMFD_02630	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
OPOHKMFD_02631	3.54e-276	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
OPOHKMFD_02632	3.13e-38	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
OPOHKMFD_02633	4.1e-273	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
OPOHKMFD_02634	1.64e-86	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
OPOHKMFD_02635	2.91e-94	-	-	-	E	-	-	-	LysE type translocator
OPOHKMFD_02636	2.96e-94	-	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
OPOHKMFD_02637	1.24e-136	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
OPOHKMFD_02638	4.09e-308	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OPOHKMFD_02639	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
OPOHKMFD_02640	2.06e-312	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
OPOHKMFD_02641	2.6e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
OPOHKMFD_02642	5.37e-216	gspA	-	-	M	-	-	-	General stress
OPOHKMFD_02643	3.49e-158	ywaF	-	-	S	-	-	-	Integral membrane protein
OPOHKMFD_02644	1.46e-113	ywaE	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_02645	2.9e-293	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OPOHKMFD_02646	0.0	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
OPOHKMFD_02647	1.08e-115	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
OPOHKMFD_02648	5.58e-64	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
OPOHKMFD_02649	2.63e-163	-	-	-	EGP	-	-	-	Permeases of the major facilitator superfamily
OPOHKMFD_02650	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
OPOHKMFD_02651	5.7e-210	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
OPOHKMFD_02652	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OPOHKMFD_02653	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
OPOHKMFD_02654	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OPOHKMFD_02655	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OPOHKMFD_02656	2.91e-178	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
OPOHKMFD_02657	1.77e-262	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
OPOHKMFD_02658	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OPOHKMFD_02659	1.3e-49	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
OPOHKMFD_02660	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OPOHKMFD_02661	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
OPOHKMFD_02662	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
OPOHKMFD_02663	8.94e-28	yxzF	-	-	-	-	-	-	-
OPOHKMFD_02664	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
OPOHKMFD_02665	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
OPOHKMFD_02666	1.95e-271	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
OPOHKMFD_02667	9.33e-178	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OPOHKMFD_02668	8.18e-211	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_02669	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
OPOHKMFD_02670	1.63e-39	-	-	-	-	-	-	-	-
OPOHKMFD_02671	5.53e-62	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
OPOHKMFD_02672	1.29e-124	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
OPOHKMFD_02673	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
OPOHKMFD_02674	9.16e-203	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OPOHKMFD_02675	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
OPOHKMFD_02676	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
OPOHKMFD_02677	9.56e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
OPOHKMFD_02678	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
OPOHKMFD_02679	2.67e-308	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
OPOHKMFD_02680	0.0	-	-	-	O	-	-	-	Peptidase family M48
OPOHKMFD_02682	5.28e-199	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
OPOHKMFD_02683	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
OPOHKMFD_02684	1.58e-209	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
OPOHKMFD_02685	1.64e-166	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OPOHKMFD_02686	8.4e-133	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OPOHKMFD_02687	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
OPOHKMFD_02688	1.74e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
OPOHKMFD_02689	3.81e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
OPOHKMFD_02690	5.15e-245	-	-	-	T	-	-	-	Signal transduction histidine kinase
OPOHKMFD_02691	1.1e-147	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
OPOHKMFD_02692	1.83e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
OPOHKMFD_02694	4.98e-112	yxjI	-	-	S	-	-	-	LURP-one-related
OPOHKMFD_02695	2.48e-276	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
OPOHKMFD_02696	1.49e-273	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
OPOHKMFD_02697	2.77e-174	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
OPOHKMFD_02698	5.91e-151	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OPOHKMFD_02699	4.46e-166	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OPOHKMFD_02700	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
OPOHKMFD_02701	1.63e-199	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
OPOHKMFD_02702	2.1e-269	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OPOHKMFD_02703	1.47e-133	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
OPOHKMFD_02704	2.12e-59	yxiS	-	-	-	-	-	-	-
OPOHKMFD_02705	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
OPOHKMFD_02706	2e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
OPOHKMFD_02707	2.07e-182	bglS	-	-	M	-	-	-	licheninase activity
OPOHKMFD_02708	5.66e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
OPOHKMFD_02709	5.32e-143	-	-	-	-	-	-	-	-
OPOHKMFD_02710	3.8e-292	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
OPOHKMFD_02711	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
OPOHKMFD_02712	6.52e-270	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
OPOHKMFD_02715	3.48e-59	yxiJ	-	-	S	-	-	-	YxiJ-like protein
OPOHKMFD_02718	7.33e-43	-	-	-	-	-	-	-	-
OPOHKMFD_02719	4.1e-111	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
OPOHKMFD_02720	2.41e-173	-	-	-	-	-	-	-	-
OPOHKMFD_02723	6.09e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF2750)
OPOHKMFD_02724	3.95e-67	yxxG	-	-	-	-	-	-	-
OPOHKMFD_02725	1.9e-88	yxiG	-	-	-	-	-	-	-
OPOHKMFD_02726	6.02e-78	-	-	-	-	-	-	-	-
OPOHKMFD_02727	3.53e-100	-	-	-	-	-	-	-	-
OPOHKMFD_02728	8.9e-119	-	-	-	S	-	-	-	Protein of unknown function (DUF4240)
OPOHKMFD_02729	8.76e-176	-	-	-	-	-	-	-	-
OPOHKMFD_02732	5.46e-101	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
OPOHKMFD_02733	3.29e-19	yxiJ	-	-	S	-	-	-	YxiJ-like protein
OPOHKMFD_02734	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
OPOHKMFD_02735	2.94e-210	yxxF	-	-	EG	-	-	-	EamA-like transporter family
OPOHKMFD_02736	6.99e-94	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
OPOHKMFD_02737	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
OPOHKMFD_02738	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
OPOHKMFD_02739	9.21e-44	-	-	-	-	-	-	-	-
OPOHKMFD_02740	1.03e-167	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
OPOHKMFD_02741	3.27e-53	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
OPOHKMFD_02742	5.38e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
OPOHKMFD_02743	0.0	-	-	-	L	-	-	-	HKD family nuclease
OPOHKMFD_02744	1.23e-78	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
OPOHKMFD_02745	3.11e-193	-	-	-	L	-	-	-	Protein of unknown function (DUF2726)
OPOHKMFD_02746	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
OPOHKMFD_02747	7.02e-103	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
OPOHKMFD_02748	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
OPOHKMFD_02749	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OPOHKMFD_02750	8.72e-297	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
OPOHKMFD_02751	8.04e-230	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
OPOHKMFD_02752	0.0	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
OPOHKMFD_02753	8.11e-299	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
OPOHKMFD_02754	2.72e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OPOHKMFD_02755	8.3e-150	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OPOHKMFD_02756	4.26e-222	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OPOHKMFD_02757	1.51e-196	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
OPOHKMFD_02758	2.21e-255	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
OPOHKMFD_02759	1.33e-310	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
OPOHKMFD_02760	5.82e-272	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
OPOHKMFD_02761	4.8e-171	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_02762	3e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
OPOHKMFD_02763	4.3e-186	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
OPOHKMFD_02764	6.27e-121	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OPOHKMFD_02765	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OPOHKMFD_02766	2.61e-235	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
OPOHKMFD_02767	2.71e-192	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
OPOHKMFD_02770	7.32e-42	yxeE	-	-	-	-	-	-	-
OPOHKMFD_02771	7.57e-28	yxeD	-	-	-	-	-	-	-
OPOHKMFD_02772	9.65e-91	-	-	-	-	-	-	-	-
OPOHKMFD_02773	3.51e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
OPOHKMFD_02774	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
OPOHKMFD_02775	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
OPOHKMFD_02776	5.21e-179	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_02777	9.03e-230	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OPOHKMFD_02778	2.8e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPOHKMFD_02779	2.83e-204	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
OPOHKMFD_02780	3.26e-193	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
OPOHKMFD_02781	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
OPOHKMFD_02782	4.44e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
OPOHKMFD_02783	8.46e-298	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
OPOHKMFD_02784	4.27e-223	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
OPOHKMFD_02785	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
OPOHKMFD_02786	1.23e-227	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
OPOHKMFD_02787	2e-199	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
OPOHKMFD_02788	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OPOHKMFD_02789	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
OPOHKMFD_02790	3.52e-224	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
OPOHKMFD_02792	2.13e-64	yxcD	-	-	S	-	-	-	Protein of unknown function (DUF2653)
OPOHKMFD_02793	2.8e-311	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
OPOHKMFD_02794	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
OPOHKMFD_02796	2.76e-40	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
OPOHKMFD_02797	2.43e-92	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
OPOHKMFD_02800	5.97e-293	-	-	-	V	ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	Peptidase C39 family
OPOHKMFD_02801	1.81e-169	-	-	-	M	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	HlyD family secretion protein
OPOHKMFD_02802	3.1e-251	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
OPOHKMFD_02803	3.42e-313	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
OPOHKMFD_02804	3.27e-41	yxaI	-	-	S	-	-	-	membrane protein domain
OPOHKMFD_02805	7.49e-137	yxaL	-	-	S	-	-	-	PQQ-like domain
OPOHKMFD_02806	3.11e-80	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
OPOHKMFD_02807	4.03e-99	yxaI	-	-	S	-	-	-	membrane protein domain
OPOHKMFD_02808	1.25e-284	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
OPOHKMFD_02809	3e-250	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
OPOHKMFD_02810	3.22e-129	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
OPOHKMFD_02811	1.23e-254	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
OPOHKMFD_02812	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
OPOHKMFD_02813	1.03e-77	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
OPOHKMFD_02814	2.19e-153	yxaC	-	-	M	-	-	-	effector of murein hydrolase
OPOHKMFD_02815	3.62e-245	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
OPOHKMFD_02816	6.4e-261	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
OPOHKMFD_02817	3.63e-163	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
OPOHKMFD_02818	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
OPOHKMFD_02819	5.87e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
OPOHKMFD_02820	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OPOHKMFD_02821	9.33e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
OPOHKMFD_02822	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
OPOHKMFD_02823	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
OPOHKMFD_02824	1.39e-37	-	2.7.1.199	-	G	ko:K02777,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
OPOHKMFD_02825	8.29e-161	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_02826	1.44e-24	-	-	-	-	-	-	-	-
OPOHKMFD_02827	5.49e-152	-	-	-	S	ko:K16916	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
OPOHKMFD_02828	3.42e-142	-	-	-	P	ko:K16917	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
OPOHKMFD_02829	3.65e-172	-	-	-	O	ko:K16922	-	ko00000,ko01002	Peptidase M50
OPOHKMFD_02830	1.35e-237	-	-	-	S	-	-	-	Radical SAM superfamily
OPOHKMFD_02831	8.12e-17	-	-	-	-	-	-	-	-
OPOHKMFD_02832	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
OPOHKMFD_02834	3.14e-200	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
OPOHKMFD_02835	2.02e-296	-	-	-	L	-	-	-	AAA ATPase domain
OPOHKMFD_02836	5e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OPOHKMFD_02838	2.24e-87	-	-	-	-	-	-	-	-
OPOHKMFD_02839	1.05e-296	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OPOHKMFD_02841	1.7e-45	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
OPOHKMFD_02842	7.19e-281	yycP	-	-	-	-	-	-	-
OPOHKMFD_02843	7.97e-168	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OPOHKMFD_02844	8.71e-110	yycN	-	-	K	-	-	-	Acetyltransferase
OPOHKMFD_02845	1.23e-238	-	-	-	S	-	-	-	aspartate phosphatase
OPOHKMFD_02847	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
OPOHKMFD_02848	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
OPOHKMFD_02849	2.04e-294	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
OPOHKMFD_02850	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
OPOHKMFD_02851	9.43e-279	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OPOHKMFD_02852	4.01e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
OPOHKMFD_02853	1.2e-200	yycI	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_02854	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_02855	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OPOHKMFD_02856	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPOHKMFD_02861	1.29e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OPOHKMFD_02862	1.34e-98	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OPOHKMFD_02863	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
OPOHKMFD_02864	3.48e-40	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
OPOHKMFD_02866	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
OPOHKMFD_02867	4.19e-283	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
OPOHKMFD_02868	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OPOHKMFD_02869	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
OPOHKMFD_02870	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
OPOHKMFD_02871	7.43e-205	yybS	-	-	S	-	-	-	membrane
OPOHKMFD_02873	5.61e-108	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
OPOHKMFD_02874	6.68e-90	yybR	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_02875	4.89e-210	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
OPOHKMFD_02876	2.34e-92	-	-	-	-	-	-	-	-
OPOHKMFD_02878	1.01e-307	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
OPOHKMFD_02879	4.38e-142	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
OPOHKMFD_02880	6.12e-185	-	-	-	-	-	-	-	-
OPOHKMFD_02881	3.02e-88	-	-	-	S	-	-	-	SnoaL-like domain
OPOHKMFD_02882	1.89e-160	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
OPOHKMFD_02883	4.31e-277	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
OPOHKMFD_02884	2.53e-208	yybE	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_02885	2.55e-100	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
OPOHKMFD_02886	1.22e-97	yybC	-	-	-	-	-	-	-
OPOHKMFD_02887	2.16e-164	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
OPOHKMFD_02888	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
OPOHKMFD_02889	1.16e-92	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
OPOHKMFD_02890	4.28e-125	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
OPOHKMFD_02891	2.07e-123	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
OPOHKMFD_02892	1.09e-87	-	-	-	S	-	-	-	YjbR
OPOHKMFD_02893	2.2e-139	yyaP	-	-	H	-	-	-	RibD C-terminal domain
OPOHKMFD_02894	1.29e-18	yddB	-	-	S	-	-	-	Conjugative transposon protein TcpC
OPOHKMFD_02897	1.3e-58	yddA	-	-	-	-	-	-	-
OPOHKMFD_02902	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
OPOHKMFD_02903	8.91e-217	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
OPOHKMFD_02904	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
OPOHKMFD_02905	1.14e-130	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
OPOHKMFD_02906	7.2e-90	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OPOHKMFD_02907	3.03e-230	ccpB	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_02908	2.07e-187	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
OPOHKMFD_02909	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OPOHKMFD_02910	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OPOHKMFD_02911	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
OPOHKMFD_02912	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
OPOHKMFD_02913	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OPOHKMFD_02914	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_02915	5.34e-227	yyaD	-	-	S	-	-	-	Membrane
OPOHKMFD_02916	9.15e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
OPOHKMFD_02917	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
OPOHKMFD_02918	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
OPOHKMFD_02919	2.27e-98	-	-	-	S	-	-	-	Bacterial PH domain
OPOHKMFD_02920	9e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
OPOHKMFD_02921	1.68e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
OPOHKMFD_02922	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
OPOHKMFD_02923	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OPOHKMFD_02924	1.83e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
OPOHKMFD_02925	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OPOHKMFD_02926	5.7e-71	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
OPOHKMFD_02927	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OPOHKMFD_02928	9.88e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OPOHKMFD_02929	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
OPOHKMFD_02930	4.54e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OPOHKMFD_02931	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
OPOHKMFD_02932	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OPOHKMFD_02933	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OPOHKMFD_02934	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
OPOHKMFD_02936	4.71e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
OPOHKMFD_02937	1.89e-173	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
OPOHKMFD_02938	8.27e-227	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPOHKMFD_02939	4.09e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPOHKMFD_02940	1.26e-216	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
OPOHKMFD_02941	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
OPOHKMFD_02942	1.35e-301	ybbC	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_02943	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
OPOHKMFD_02944	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
OPOHKMFD_02945	3.46e-302	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
OPOHKMFD_02946	5.43e-194	ybbH	-	-	K	-	-	-	transcriptional
OPOHKMFD_02947	1.35e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OPOHKMFD_02948	8.99e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
OPOHKMFD_02949	2.43e-100	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
OPOHKMFD_02955	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
OPOHKMFD_02956	6.45e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
OPOHKMFD_02957	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OPOHKMFD_02958	3.55e-291	ybbR	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_02959	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OPOHKMFD_02960	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OPOHKMFD_02961	2.87e-70	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OPOHKMFD_02962	1.27e-138	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OPOHKMFD_02963	6.9e-77	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
OPOHKMFD_02964	4.32e-126	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OPOHKMFD_02965	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
OPOHKMFD_02966	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
OPOHKMFD_02967	2.32e-119	ybcF	-	-	P	-	-	-	carbonic anhydrase
OPOHKMFD_02969	1.6e-63	-	-	-	-	-	-	-	-
OPOHKMFD_02970	7.26e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
OPOHKMFD_02971	3.85e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
OPOHKMFD_02972	6.59e-258	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
OPOHKMFD_02973	9.98e-75	-	-	-	-	-	-	-	-
OPOHKMFD_02975	1.14e-177	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
OPOHKMFD_02976	1.05e-192	ybdN	-	-	-	-	-	-	-
OPOHKMFD_02977	8.24e-270	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
OPOHKMFD_02978	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
OPOHKMFD_02979	5.46e-51	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
OPOHKMFD_02980	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
OPOHKMFD_02981	3.86e-195	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
OPOHKMFD_02982	7.67e-314	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
OPOHKMFD_02983	1.11e-54	ybyB	-	-	-	-	-	-	-
OPOHKMFD_02984	0.0	ybeC	-	-	E	-	-	-	amino acid
OPOHKMFD_02985	1.72e-211	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
OPOHKMFD_02986	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
OPOHKMFD_02987	1.02e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
OPOHKMFD_02988	7.04e-217	ybfA	-	-	K	-	-	-	FR47-like protein
OPOHKMFD_02989	2.63e-284	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
OPOHKMFD_02992	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
OPOHKMFD_02993	3.56e-206	ybfH	-	-	EG	-	-	-	EamA-like transporter family
OPOHKMFD_02994	7.39e-188	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
OPOHKMFD_02995	1.27e-43	-	-	-	K	-	-	-	sigma factor activity
OPOHKMFD_02996	2.73e-28	xhlB	-	-	S	-	-	-	SPP1 phage holin
OPOHKMFD_02997	4.74e-207	-	-	GH19	M	ko:K03791	-	ko00000	Lysin motif
OPOHKMFD_02998	4.12e-73	-	-	-	-	-	-	-	-
OPOHKMFD_02999	1.46e-267	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OPOHKMFD_03000	6.86e-228	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
OPOHKMFD_03002	5.56e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase family
OPOHKMFD_03003	2.81e-123	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OPOHKMFD_03004	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
OPOHKMFD_03005	2.06e-188	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
OPOHKMFD_03006	1.58e-59	ybfN	-	-	-	-	-	-	-
OPOHKMFD_03007	0.0	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
OPOHKMFD_03008	6.73e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
OPOHKMFD_03009	4.25e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OPOHKMFD_03010	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
OPOHKMFD_03011	3.52e-173	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OPOHKMFD_03012	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
OPOHKMFD_03014	3.44e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
OPOHKMFD_03015	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
OPOHKMFD_03016	1.29e-233	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
OPOHKMFD_03017	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
OPOHKMFD_03018	5.08e-237	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
OPOHKMFD_03019	3.55e-294	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OPOHKMFD_03020	9.96e-217	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
OPOHKMFD_03021	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
OPOHKMFD_03022	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OPOHKMFD_03023	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
OPOHKMFD_03024	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
OPOHKMFD_03025	2.3e-161	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
OPOHKMFD_03026	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
OPOHKMFD_03027	1.74e-222	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
OPOHKMFD_03028	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
OPOHKMFD_03029	9.95e-216	eamA1	-	-	EG	-	-	-	spore germination
OPOHKMFD_03030	2.61e-160	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPOHKMFD_03031	6.21e-214	ycbM	-	-	T	-	-	-	Histidine kinase
OPOHKMFD_03032	5.32e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_03033	4.25e-150	-	-	-	S	-	-	-	ABC-2 family transporter protein
OPOHKMFD_03034	1.82e-75	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
OPOHKMFD_03035	4.29e-101	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
OPOHKMFD_03036	3.68e-172	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
OPOHKMFD_03037	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
OPOHKMFD_03038	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OPOHKMFD_03039	7.6e-160	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OPOHKMFD_03040	6.93e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OPOHKMFD_03041	4.86e-259	ycbU	-	-	E	-	-	-	Selenocysteine lyase
OPOHKMFD_03042	1.24e-302	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
OPOHKMFD_03043	1.54e-130	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
OPOHKMFD_03044	1.69e-257	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
OPOHKMFD_03045	6.64e-146	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OPOHKMFD_03046	8.72e-78	-	-	-	S	-	-	-	RDD family
OPOHKMFD_03047	1.01e-254	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
OPOHKMFD_03048	1.98e-209	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
OPOHKMFD_03049	5.64e-162	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
OPOHKMFD_03050	2.2e-170	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
OPOHKMFD_03051	9.33e-256	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
OPOHKMFD_03052	3.37e-222	yccK	-	-	C	-	-	-	Aldo keto reductase
OPOHKMFD_03053	1.35e-241	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
OPOHKMFD_03054	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
OPOHKMFD_03055	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
OPOHKMFD_03056	3.91e-125	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
OPOHKMFD_03057	1.42e-248	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
OPOHKMFD_03058	2.39e-180	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
OPOHKMFD_03059	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
OPOHKMFD_03060	1.95e-221	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
OPOHKMFD_03061	1.99e-170	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
OPOHKMFD_03062	4.63e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
OPOHKMFD_03063	3.44e-237	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OPOHKMFD_03064	3.75e-141	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
OPOHKMFD_03065	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
OPOHKMFD_03066	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
OPOHKMFD_03067	4.1e-176	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
OPOHKMFD_03068	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
OPOHKMFD_03069	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
OPOHKMFD_03070	1.9e-278	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
OPOHKMFD_03071	1.42e-204	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
OPOHKMFD_03072	4.82e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
OPOHKMFD_03073	8.99e-293	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
OPOHKMFD_03074	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
OPOHKMFD_03075	1.65e-209	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
OPOHKMFD_03076	1.69e-277	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
OPOHKMFD_03077	0.0	ycgA	-	-	S	-	-	-	Membrane
OPOHKMFD_03078	1.25e-127	ycgB	-	-	-	-	-	-	-
OPOHKMFD_03079	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
OPOHKMFD_03080	1.19e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
OPOHKMFD_03081	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
OPOHKMFD_03082	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
OPOHKMFD_03083	3.7e-101	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
OPOHKMFD_03084	6.42e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
OPOHKMFD_03085	1.85e-195	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
OPOHKMFD_03086	9.32e-317	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
OPOHKMFD_03087	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
OPOHKMFD_03088	5.24e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
OPOHKMFD_03089	1.26e-138	tmrB	-	-	S	-	-	-	AAA domain
OPOHKMFD_03091	8.64e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OPOHKMFD_03092	1.76e-184	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
OPOHKMFD_03093	1.33e-226	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
OPOHKMFD_03094	4.48e-231	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
OPOHKMFD_03095	4.49e-186	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
OPOHKMFD_03096	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
OPOHKMFD_03097	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
OPOHKMFD_03098	0.0	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OPOHKMFD_03099	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
OPOHKMFD_03100	3.82e-195	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
OPOHKMFD_03101	3.19e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
OPOHKMFD_03102	1.27e-55	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
OPOHKMFD_03103	1.72e-92	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
OPOHKMFD_03104	1.58e-240	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
OPOHKMFD_03105	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
OPOHKMFD_03106	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
OPOHKMFD_03107	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OPOHKMFD_03108	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OPOHKMFD_03109	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
OPOHKMFD_03110	5.51e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
OPOHKMFD_03111	2.76e-218	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
OPOHKMFD_03112	2.1e-140	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
OPOHKMFD_03113	6.78e-291	yciC	-	-	S	-	-	-	GTPases (G3E family)
OPOHKMFD_03114	2.99e-149	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
OPOHKMFD_03115	3.09e-186	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
OPOHKMFD_03117	1.38e-47	yckC	-	-	S	-	-	-	membrane
OPOHKMFD_03118	4.82e-67	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
OPOHKMFD_03119	7.43e-58	-	-	-	K	-	-	-	MarR family
OPOHKMFD_03120	9e-32	-	-	-	-	-	-	-	-
OPOHKMFD_03121	1.16e-154	-	-	-	S	-	-	-	AAA domain
OPOHKMFD_03122	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
OPOHKMFD_03123	4.78e-91	nin	-	-	S	-	-	-	Competence protein J (ComJ)
OPOHKMFD_03124	3.23e-99	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
OPOHKMFD_03125	1.52e-267	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
OPOHKMFD_03126	1.13e-126	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
OPOHKMFD_03127	5.63e-137	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
OPOHKMFD_03128	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
OPOHKMFD_03129	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OPOHKMFD_03130	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OPOHKMFD_03131	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
OPOHKMFD_03132	2.71e-178	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
OPOHKMFD_03133	6.26e-288	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
OPOHKMFD_03134	2.99e-122	-	-	-	S	-	-	-	YcxB-like protein
OPOHKMFD_03135	3.27e-205	ycxC	-	-	EG	-	-	-	EamA-like transporter family
OPOHKMFD_03136	0.0	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
OPOHKMFD_03137	2.02e-146	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
OPOHKMFD_03138	8.71e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
OPOHKMFD_03139	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
OPOHKMFD_03140	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
OPOHKMFD_03141	3.54e-187	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
OPOHKMFD_03142	1.46e-206	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
OPOHKMFD_03143	2.24e-140	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
OPOHKMFD_03144	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
OPOHKMFD_03145	9.86e-53	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
OPOHKMFD_03146	2.51e-108	yclD	-	-	-	-	-	-	-
OPOHKMFD_03147	7.82e-202	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
OPOHKMFD_03148	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
OPOHKMFD_03149	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
OPOHKMFD_03151	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
OPOHKMFD_03152	3.26e-294	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
OPOHKMFD_03153	1.48e-250	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
OPOHKMFD_03154	2.39e-155	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
OPOHKMFD_03155	6.2e-277	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
OPOHKMFD_03156	4.22e-164	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPOHKMFD_03157	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
OPOHKMFD_03158	2.18e-97	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
OPOHKMFD_03160	1.58e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
OPOHKMFD_03161	7.93e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
OPOHKMFD_03162	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
OPOHKMFD_03163	1.09e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPOHKMFD_03164	3.16e-209	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPOHKMFD_03165	2.29e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_03166	5.72e-213	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
OPOHKMFD_03167	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
OPOHKMFD_03168	2.91e-198	ycnC	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_03169	8.65e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
OPOHKMFD_03170	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
OPOHKMFD_03171	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
OPOHKMFD_03172	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OPOHKMFD_03173	9.35e-311	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OPOHKMFD_03174	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OPOHKMFD_03175	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
OPOHKMFD_03176	5.9e-187	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPOHKMFD_03177	1.07e-138	ycnI	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_03178	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
OPOHKMFD_03179	5.18e-139	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
OPOHKMFD_03180	1.34e-74	-	-	-	-	-	-	-	-
OPOHKMFD_03181	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
OPOHKMFD_03182	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
OPOHKMFD_03183	2.54e-267	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
OPOHKMFD_03184	1.01e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
OPOHKMFD_03186	6.21e-97	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
OPOHKMFD_03187	4.21e-144	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
OPOHKMFD_03188	7.69e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
OPOHKMFD_03190	1.9e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
OPOHKMFD_03191	3.14e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
OPOHKMFD_03192	1.32e-271	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
OPOHKMFD_03193	2.01e-189	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
OPOHKMFD_03194	2.05e-172	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
OPOHKMFD_03195	1.91e-236	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
OPOHKMFD_03196	3.8e-171	kipR	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_03197	1.91e-150	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
OPOHKMFD_03199	8.97e-65	yczJ	-	-	S	-	-	-	biosynthesis
OPOHKMFD_03200	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
OPOHKMFD_03201	8.6e-220	ycsN	-	-	S	-	-	-	Oxidoreductase
OPOHKMFD_03202	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
OPOHKMFD_03203	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
OPOHKMFD_03204	6.78e-126	ydaC	-	-	Q	-	-	-	Methyltransferase domain
OPOHKMFD_03205	3.74e-207	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPOHKMFD_03206	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
OPOHKMFD_03207	2.58e-131	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OPOHKMFD_03208	5.24e-101	ydaG	-	-	S	-	-	-	general stress protein
OPOHKMFD_03209	1.87e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
OPOHKMFD_03210	3.12e-61	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
OPOHKMFD_03211	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
OPOHKMFD_03212	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OPOHKMFD_03213	1.03e-265	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OPOHKMFD_03214	9.39e-195	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
OPOHKMFD_03215	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
OPOHKMFD_03216	1.93e-304	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
OPOHKMFD_03217	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
OPOHKMFD_03218	0.0	ydaO	-	-	E	-	-	-	amino acid
OPOHKMFD_03219	2.44e-99	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
OPOHKMFD_03220	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
OPOHKMFD_03222	1.84e-34	-	-	-	-	-	-	-	-
OPOHKMFD_03223	2.18e-90	sdpB	-	-	S	-	-	-	Protein conserved in bacteria
OPOHKMFD_03225	2.14e-53	-	-	-	-	-	-	-	-
OPOHKMFD_03226	3.9e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
OPOHKMFD_03227	1.67e-42	ydaS	-	-	S	-	-	-	membrane
OPOHKMFD_03228	2.25e-100	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
OPOHKMFD_03229	2.49e-189	ydbA	-	-	P	-	-	-	EcsC protein family
OPOHKMFD_03230	3.3e-10	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
OPOHKMFD_03231	1.25e-74	ydbB	-	-	G	-	-	-	Cupin domain
OPOHKMFD_03232	3.53e-80	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
OPOHKMFD_03233	2.24e-197	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
OPOHKMFD_03234	3.66e-253	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
OPOHKMFD_03235	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
OPOHKMFD_03236	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
OPOHKMFD_03237	1.27e-289	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OPOHKMFD_03238	1.32e-230	ydbI	-	-	S	-	-	-	AI-2E family transporter
OPOHKMFD_03239	2.66e-218	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_03240	2.99e-159	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OPOHKMFD_03241	9.32e-70	ydbL	-	-	-	-	-	-	-
OPOHKMFD_03242	1.5e-279	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
OPOHKMFD_03243	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
OPOHKMFD_03245	2.72e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OPOHKMFD_03246	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
OPOHKMFD_03247	3.58e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
OPOHKMFD_03248	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
OPOHKMFD_03249	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
OPOHKMFD_03250	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
OPOHKMFD_03251	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
OPOHKMFD_03252	2.53e-139	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
OPOHKMFD_03253	1.95e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
OPOHKMFD_03254	4.66e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
OPOHKMFD_03255	5.29e-284	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OPOHKMFD_03256	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
OPOHKMFD_03257	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
OPOHKMFD_03258	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
OPOHKMFD_03259	7.34e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
OPOHKMFD_03260	8.56e-90	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
OPOHKMFD_03261	1.31e-243	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
OPOHKMFD_03262	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
OPOHKMFD_03263	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
OPOHKMFD_03264	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OPOHKMFD_03265	4.38e-140	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
OPOHKMFD_03268	1.32e-106	ydcG	-	-	S	-	-	-	EVE domain
OPOHKMFD_03269	1.04e-99	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
OPOHKMFD_03270	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
OPOHKMFD_03271	1.53e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
OPOHKMFD_03279	2.97e-268	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
OPOHKMFD_03280	1.65e-118	-	-	-	E	-	-	-	IrrE N-terminal-like domain
OPOHKMFD_03281	1.91e-81	-	-	-	K	-	-	-	Transcriptional
OPOHKMFD_03282	8.96e-24	-	-	-	-	-	-	-	-
OPOHKMFD_03283	1.35e-55	-	-	-	-	-	-	-	-
OPOHKMFD_03285	1.84e-83	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
OPOHKMFD_03286	0.0	ydcQ	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk spoiiie family protein
OPOHKMFD_03287	1.63e-257	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
OPOHKMFD_03288	3.97e-49	-	-	-	-	-	-	-	-
OPOHKMFD_03290	8.25e-63	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
OPOHKMFD_03291	2.33e-57	-	-	-	-	-	-	-	-
OPOHKMFD_03292	1.05e-51	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
OPOHKMFD_03293	1.68e-82	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
OPOHKMFD_03295	4.75e-245	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
OPOHKMFD_03296	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
OPOHKMFD_03297	1.45e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
OPOHKMFD_03298	1.59e-39	ydzE	-	-	EG	-	-	-	spore germination
OPOHKMFD_03299	1.08e-209	-	-	-	K	-	-	-	AraC-like ligand binding domain
OPOHKMFD_03300	3.37e-222	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OPOHKMFD_03301	9.2e-210	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
OPOHKMFD_03302	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OPOHKMFD_03303	1.27e-275	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
OPOHKMFD_03304	3.21e-70	ydeH	-	-	-	-	-	-	-
OPOHKMFD_03305	5.52e-133	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
OPOHKMFD_03306	2.67e-144	-	-	-	-	-	-	-	-
OPOHKMFD_03307	1.28e-194	ydeK	-	-	EG	-	-	-	-transporter
OPOHKMFD_03308	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OPOHKMFD_03309	3.68e-97	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
OPOHKMFD_03310	1.56e-131	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
OPOHKMFD_03311	1.02e-72	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
OPOHKMFD_03312	6.56e-194	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
OPOHKMFD_03313	3e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
OPOHKMFD_03314	7.13e-294	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OPOHKMFD_03315	5.44e-189	-	-	-	J	-	-	-	GNAT acetyltransferase
OPOHKMFD_03316	1.45e-205	-	-	-	EG	-	-	-	EamA-like transporter family
OPOHKMFD_03317	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OPOHKMFD_03318	1.54e-232	-	4.1.1.86	-	E	ko:K13745	ko00260,ko01120,map00260,map01120	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase conserved domain
OPOHKMFD_03319	4.04e-149	ydfE	-	-	S	-	-	-	Flavin reductase like domain
OPOHKMFD_03320	1.23e-157	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
OPOHKMFD_03321	3.92e-104	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OPOHKMFD_03322	1.19e-214	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OPOHKMFD_03323	2.3e-142	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OPOHKMFD_03324	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
OPOHKMFD_03325	8.6e-220	-	-	-	S	-	-	-	Alpha/beta hydrolase family
OPOHKMFD_03326	7.6e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
OPOHKMFD_03327	6.84e-186	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
OPOHKMFD_03328	5.22e-199	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OPOHKMFD_03329	3.45e-145	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
OPOHKMFD_03330	9.49e-239	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
OPOHKMFD_03331	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
OPOHKMFD_03332	9.63e-77	ydfQ	-	-	CO	-	-	-	Thioredoxin
OPOHKMFD_03333	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
OPOHKMFD_03334	5.33e-39	-	-	-	-	-	-	-	-
OPOHKMFD_03336	6.08e-153	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
OPOHKMFD_03337	4.44e-160	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
OPOHKMFD_03338	3.13e-99	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
OPOHKMFD_03339	2.74e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
OPOHKMFD_03340	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
OPOHKMFD_03341	6.13e-55	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
OPOHKMFD_03342	3.29e-61	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
OPOHKMFD_03343	7e-71	-	-	-	S	-	-	-	DoxX-like family
OPOHKMFD_03344	2.49e-114	yycN	-	-	K	-	-	-	Acetyltransferase
OPOHKMFD_03345	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
OPOHKMFD_03346	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
OPOHKMFD_03347	1.16e-107	-	-	-	S	-	-	-	DinB family
OPOHKMFD_03348	3.87e-102	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
OPOHKMFD_03349	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
OPOHKMFD_03350	6.42e-147	ydgI	-	-	C	-	-	-	nitroreductase
OPOHKMFD_03351	3.29e-90	-	-	-	K	-	-	-	Winged helix DNA-binding domain
OPOHKMFD_03352	9.89e-266	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
OPOHKMFD_03353	1.02e-154	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
OPOHKMFD_03354	4.31e-157	ydhC	-	-	K	-	-	-	FCD
OPOHKMFD_03355	5.16e-309	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
OPOHKMFD_03356	3.91e-289	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OPOHKMFD_03357	1.43e-161	-	-	-	-	-	-	-	-
OPOHKMFD_03358	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
OPOHKMFD_03359	2.74e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
OPOHKMFD_03361	7.65e-108	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
OPOHKMFD_03362	1.56e-230	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
OPOHKMFD_03363	2.59e-126	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
OPOHKMFD_03364	2.56e-254	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
OPOHKMFD_03365	1.88e-63	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
OPOHKMFD_03366	3.39e-67	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
OPOHKMFD_03367	3.76e-304	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OPOHKMFD_03368	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
OPOHKMFD_03369	7.75e-171	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
OPOHKMFD_03370	1.65e-212	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
OPOHKMFD_03371	3.44e-238	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
OPOHKMFD_03372	2.64e-268	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
OPOHKMFD_03373	4.79e-100	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
OPOHKMFD_03374	7.94e-22	ydhU	-	-	P	ko:K07217	-	ko00000	Manganese containing catalase
OPOHKMFD_03377	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
OPOHKMFD_03378	3.38e-73	ygzB	-	-	S	-	-	-	UPF0295 protein
OPOHKMFD_03379	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
OPOHKMFD_03380	1.69e-112	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
OPOHKMFD_03381	1.89e-311	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
OPOHKMFD_03382	1.87e-238	ygaE	-	-	S	-	-	-	Membrane
OPOHKMFD_03383	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
OPOHKMFD_03384	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
OPOHKMFD_03385	8.19e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
OPOHKMFD_03386	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
OPOHKMFD_03387	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPOHKMFD_03388	1.73e-48	yfhS	-	-	-	-	-	-	-
OPOHKMFD_03389	1.31e-265	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
OPOHKMFD_03390	2.07e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
OPOHKMFD_03391	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
OPOHKMFD_03392	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
OPOHKMFD_03393	1.13e-217	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
OPOHKMFD_03394	1.93e-61	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
OPOHKMFD_03395	2.42e-117	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
OPOHKMFD_03396	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
OPOHKMFD_03397	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
OPOHKMFD_03398	2.45e-268	yfhI	-	-	EGP	-	-	-	-transporter
OPOHKMFD_03400	4.58e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
OPOHKMFD_03401	9.32e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
OPOHKMFD_03402	8.92e-219	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
OPOHKMFD_03404	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
OPOHKMFD_03405	1.66e-137	yfhC	-	-	C	-	-	-	nitroreductase
OPOHKMFD_03406	1.58e-207	yfhB	-	-	S	-	-	-	PhzF family
OPOHKMFD_03407	7.36e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPOHKMFD_03408	8.91e-225	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPOHKMFD_03409	3.83e-231	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
OPOHKMFD_03410	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OPOHKMFD_03411	2.11e-103	yfiV	-	-	K	-	-	-	transcriptional
OPOHKMFD_03412	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
OPOHKMFD_03413	1.15e-127	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
OPOHKMFD_03414	2.54e-271	yfiS	-	-	EGP	-	-	-	Major facilitator superfamily
OPOHKMFD_03415	1.34e-137	yfiR	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_03416	9.34e-253	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
OPOHKMFD_03417	7.87e-128	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OPOHKMFD_03418	1.89e-128	padR	-	-	K	-	-	-	transcriptional
OPOHKMFD_03419	4.19e-263	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
OPOHKMFD_03420	1.78e-265	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
OPOHKMFD_03421	5.1e-213	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_03422	1.01e-144	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
OPOHKMFD_03423	4.15e-240	baeS	-	-	T	-	-	-	Histidine kinase
OPOHKMFD_03424	2e-206	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
OPOHKMFD_03425	2.01e-84	yfiD3	-	-	S	-	-	-	DoxX
OPOHKMFD_03426	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
OPOHKMFD_03427	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
OPOHKMFD_03428	0.0	yobO	-	-	M	-	-	-	COG5434 Endopolygalacturonase
OPOHKMFD_03429	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
OPOHKMFD_03430	8.69e-181	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
OPOHKMFD_03431	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OPOHKMFD_03434	4.94e-88	-	-	-	S	-	-	-	LXG domain of WXG superfamily
OPOHKMFD_03436	6.81e-25	-	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_03439	5.59e-61	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
OPOHKMFD_03440	2.26e-269	yfjB	-	-	-	-	-	-	-
OPOHKMFD_03441	2.5e-185	yfjC	-	-	-	-	-	-	-
OPOHKMFD_03442	1.49e-131	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
OPOHKMFD_03443	1.07e-100	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
OPOHKMFD_03444	1.05e-74	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
OPOHKMFD_03445	8.16e-36	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
OPOHKMFD_03446	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
OPOHKMFD_03447	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OPOHKMFD_03448	2.22e-260	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OPOHKMFD_03449	6.47e-243	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OPOHKMFD_03450	1.36e-244	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OPOHKMFD_03452	2.53e-106	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
OPOHKMFD_03453	9.53e-241	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OPOHKMFD_03454	3.04e-59	-	-	-	S	-	-	-	YfzA-like protein
OPOHKMFD_03455	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OPOHKMFD_03456	7.91e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OPOHKMFD_03457	7.8e-237	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
OPOHKMFD_03458	4.43e-190	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
OPOHKMFD_03459	4.19e-197	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
OPOHKMFD_03460	3.26e-36	yfjT	-	-	-	-	-	-	-
OPOHKMFD_03461	1.19e-281	yfkA	-	-	S	-	-	-	YfkB-like domain
OPOHKMFD_03462	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
OPOHKMFD_03463	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
OPOHKMFD_03464	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
OPOHKMFD_03465	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
OPOHKMFD_03466	1.64e-12	-	-	-	-	-	-	-	-
OPOHKMFD_03467	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
OPOHKMFD_03468	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
OPOHKMFD_03469	9.78e-107	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OPOHKMFD_03470	5.99e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
OPOHKMFD_03471	6.21e-266	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
OPOHKMFD_03472	2.23e-113	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
OPOHKMFD_03473	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
OPOHKMFD_03474	6.16e-160	frp	-	-	C	-	-	-	nitroreductase
OPOHKMFD_03475	1.24e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
OPOHKMFD_03476	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
OPOHKMFD_03477	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
OPOHKMFD_03478	1.36e-32	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
OPOHKMFD_03479	0.0	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
OPOHKMFD_03480	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
OPOHKMFD_03481	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
OPOHKMFD_03482	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
OPOHKMFD_03483	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
OPOHKMFD_03484	1.48e-65	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
OPOHKMFD_03485	6.9e-27	yflI	-	-	-	-	-	-	-
OPOHKMFD_03486	3.16e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
OPOHKMFD_03487	3.42e-157	yflK	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_03488	2.97e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
OPOHKMFD_03489	5.59e-275	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OPOHKMFD_03490	1.7e-192	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
OPOHKMFD_03491	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
OPOHKMFD_03492	1.62e-229	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
OPOHKMFD_03493	2.2e-151	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
OPOHKMFD_03494	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
OPOHKMFD_03495	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
OPOHKMFD_03496	2.45e-307	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
OPOHKMFD_03497	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
OPOHKMFD_03498	1.06e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
OPOHKMFD_03499	1.17e-220	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
OPOHKMFD_03500	8.17e-221	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPOHKMFD_03501	2.01e-221	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPOHKMFD_03502	1.4e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
OPOHKMFD_03503	9.5e-239	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
OPOHKMFD_03504	1.53e-97	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
OPOHKMFD_03505	4.19e-263	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
OPOHKMFD_03506	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OPOHKMFD_03507	5.23e-35	-	-	-	-	-	-	-	-
OPOHKMFD_03508	7.24e-265	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
OPOHKMFD_03509	3.54e-90	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
OPOHKMFD_03510	7.28e-96	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
OPOHKMFD_03511	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OPOHKMFD_03512	7.3e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
OPOHKMFD_03513	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OPOHKMFD_03514	2.4e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
OPOHKMFD_03515	2.49e-166	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
OPOHKMFD_03516	6.21e-268	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
OPOHKMFD_03517	3.88e-242	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
OPOHKMFD_03518	2.44e-286	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
OPOHKMFD_03519	3.99e-231	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
OPOHKMFD_03520	1.37e-219	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
OPOHKMFD_03521	9.83e-187	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
OPOHKMFD_03522	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
OPOHKMFD_03523	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
OPOHKMFD_03524	7.06e-251	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
OPOHKMFD_03525	2.55e-65	-	-	-	-	-	-	-	-
OPOHKMFD_03526	2.43e-263	yetM	-	-	CH	-	-	-	FAD binding domain
OPOHKMFD_03527	1.86e-114	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
OPOHKMFD_03528	1.42e-200	-	-	-	EG	-	-	-	EamA-like transporter family
OPOHKMFD_03529	2.55e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
OPOHKMFD_03530	4.46e-27	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
OPOHKMFD_03531	7.23e-184	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OPOHKMFD_03532	1.75e-44	-	-	-	-	-	-	-	-
OPOHKMFD_03533	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OPOHKMFD_03534	4.67e-73	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
OPOHKMFD_03535	1.81e-157	yetF	-	-	S	-	-	-	membrane
OPOHKMFD_03536	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
OPOHKMFD_03537	7.85e-209	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
OPOHKMFD_03538	2.78e-225	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
OPOHKMFD_03539	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
OPOHKMFD_03540	0.0	yetA	-	-	-	-	-	-	-
OPOHKMFD_03541	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
OPOHKMFD_03542	7.51e-159	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
OPOHKMFD_03543	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
OPOHKMFD_03544	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
OPOHKMFD_03545	4.02e-145	-	-	-	S	-	-	-	Protein of unknown function, DUF624
OPOHKMFD_03546	1.25e-163	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
OPOHKMFD_03547	1.19e-169	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
OPOHKMFD_03548	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_03549	3.26e-253	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
OPOHKMFD_03550	5.33e-212	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
OPOHKMFD_03551	4.76e-217	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
OPOHKMFD_03552	4.13e-314	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
OPOHKMFD_03553	2.93e-259	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
OPOHKMFD_03554	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OPOHKMFD_03555	8.56e-131	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
OPOHKMFD_03557	1.19e-130	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
OPOHKMFD_03558	1.04e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
OPOHKMFD_03559	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
OPOHKMFD_03560	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
OPOHKMFD_03561	1.23e-195	yesF	-	-	GM	-	-	-	NAD(P)H-binding
OPOHKMFD_03562	1.6e-103	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
OPOHKMFD_03563	1.16e-128	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_03565	6.29e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
OPOHKMFD_03567	9.61e-269	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
OPOHKMFD_03568	3.65e-13	-	-	-	S	-	-	-	Pfam:DUF1311
OPOHKMFD_03569	8.06e-126	-	-	-	L	-	-	-	endonuclease activity
OPOHKMFD_03571	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
OPOHKMFD_03572	2.48e-66	-	-	-	S	-	-	-	Protein of unknown function, DUF600
OPOHKMFD_03573	2.39e-68	-	-	-	S	-	-	-	Protein of unknown function, DUF600
OPOHKMFD_03574	2.52e-102	-	-	-	S	-	-	-	Protein of unknown function, DUF600
OPOHKMFD_03575	8.51e-06	-	-	-	-	-	-	-	-
OPOHKMFD_03576	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OPOHKMFD_03577	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OPOHKMFD_03578	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OPOHKMFD_03579	4.91e-189	yerO	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_03580	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OPOHKMFD_03582	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OPOHKMFD_03583	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OPOHKMFD_03584	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
OPOHKMFD_03585	9.99e-250	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
OPOHKMFD_03586	1.77e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
OPOHKMFD_03587	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OPOHKMFD_03588	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
OPOHKMFD_03589	9.04e-161	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OPOHKMFD_03591	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
OPOHKMFD_03592	7.62e-68	yerC	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_03593	9.58e-244	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
OPOHKMFD_03594	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
OPOHKMFD_03595	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
OPOHKMFD_03596	1.67e-291	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
OPOHKMFD_03597	1.06e-95	-	-	-	K	-	-	-	helix_turn_helix ASNC type
OPOHKMFD_03598	1.63e-297	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
OPOHKMFD_03599	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
OPOHKMFD_03600	7.3e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OPOHKMFD_03601	9.88e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
OPOHKMFD_03602	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OPOHKMFD_03603	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OPOHKMFD_03604	1.15e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OPOHKMFD_03605	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OPOHKMFD_03606	1.18e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
OPOHKMFD_03607	8.03e-314	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OPOHKMFD_03608	3.4e-274	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OPOHKMFD_03609	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OPOHKMFD_03610	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
OPOHKMFD_03611	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
OPOHKMFD_03613	5.85e-165	yebC	-	-	M	-	-	-	Membrane
OPOHKMFD_03614	4.86e-283	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
OPOHKMFD_03615	3.15e-312	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
OPOHKMFD_03616	1.05e-109	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
OPOHKMFD_03617	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
OPOHKMFD_03618	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
OPOHKMFD_03619	5.31e-284	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
OPOHKMFD_03620	3.25e-225	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
OPOHKMFD_03621	1.76e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OPOHKMFD_03622	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
OPOHKMFD_03623	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
OPOHKMFD_03624	1.54e-225	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
OPOHKMFD_03625	1.78e-202	-	-	-	I	-	-	-	Alpha/beta hydrolase family
OPOHKMFD_03626	8.2e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
OPOHKMFD_03628	2.81e-208	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
OPOHKMFD_03629	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
OPOHKMFD_03630	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
OPOHKMFD_03631	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
OPOHKMFD_03632	5.58e-248	-	-	-	S	-	-	-	Ion transport 2 domain protein
OPOHKMFD_03633	4.21e-202	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
OPOHKMFD_03634	8.23e-170	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
OPOHKMFD_03635	4.25e-227	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OPOHKMFD_03636	3.1e-147	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
OPOHKMFD_03637	1.73e-220	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
OPOHKMFD_03638	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
OPOHKMFD_03639	1.51e-258	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
OPOHKMFD_03640	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
OPOHKMFD_03641	1.19e-30	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
OPOHKMFD_03642	4.31e-82	yozB	-	-	S	ko:K08976	-	ko00000	Membrane
OPOHKMFD_03645	7.05e-293	-	-	-	S	-	-	-	Bacterial EndoU nuclease
OPOHKMFD_03646	1.93e-53	-	-	-	-	-	-	-	-
OPOHKMFD_03650	1.64e-106	-	-	-	-	-	-	-	-
OPOHKMFD_03651	1.36e-37	-	-	-	K	-	-	-	Helix-turn-helix domain
OPOHKMFD_03652	4.72e-51	-	-	-	S	-	-	-	protein domain associated with
OPOHKMFD_03653	2.05e-158	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
OPOHKMFD_03654	1.25e-38	xhlB	-	-	S	-	-	-	SPP1 phage holin
OPOHKMFD_03655	7.72e-37	xhlA	-	-	S	-	-	-	Haemolysin XhlA
OPOHKMFD_03656	4.24e-122	-	3.1.4.46, 5.4.2.11	-	C	ko:K01126,ko:K01834	ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	glycerophosphoryl diester phosphodiesterase
OPOHKMFD_03658	4.39e-12	-	-	-	-	-	-	-	-
OPOHKMFD_03659	2.68e-22	-	-	-	-	-	-	-	-
OPOHKMFD_03660	1.22e-78	-	-	-	-	-	-	-	-
OPOHKMFD_03661	1.84e-130	-	-	-	S	-	-	-	homolog of phage Mu protein gp47
OPOHKMFD_03662	6.43e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2634)
OPOHKMFD_03664	3.69e-111	-	-	-	-	-	-	-	-
OPOHKMFD_03665	1.13e-41	-	-	-	-	-	-	-	-
OPOHKMFD_03666	6.22e-47	-	-	-	M	-	-	-	LysM domain
OPOHKMFD_03667	2.41e-161	-	-	-	N	-	-	-	phage tail tape measure protein
OPOHKMFD_03668	1.59e-10	-	-	-	-	-	-	-	-
OPOHKMFD_03669	8.46e-46	-	-	-	-	-	-	-	-
OPOHKMFD_03670	4.59e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF3383)
OPOHKMFD_03671	6.84e-40	-	-	-	-	-	-	-	-
OPOHKMFD_03673	2.44e-61	-	-	-	-	-	-	-	-
OPOHKMFD_03675	1.04e-39	-	-	-	S	-	-	-	Phage Mu protein F like protein
OPOHKMFD_03677	8.27e-157	-	-	-	S	-	-	-	Phage capsid family
OPOHKMFD_03678	4.59e-77	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
OPOHKMFD_03680	1.61e-192	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
OPOHKMFD_03681	5.15e-233	-	-	-	S	-	-	-	Terminase-like family
OPOHKMFD_03682	7.14e-113	yqaS	-	-	L	-	-	-	DNA packaging
OPOHKMFD_03685	8.99e-20	-	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_03687	4.33e-90	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OPOHKMFD_03693	2.97e-26	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
OPOHKMFD_03695	1.83e-70	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
OPOHKMFD_03696	6.29e-13	-	-	-	S	-	-	-	YopX protein
OPOHKMFD_03698	5.09e-164	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
OPOHKMFD_03699	1.23e-43	yqaL	-	-	L	-	-	-	DnaD domain protein
OPOHKMFD_03700	2.54e-171	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
OPOHKMFD_03701	1.33e-193	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
OPOHKMFD_03706	4.65e-112	-	-	-	-	-	-	-	-
OPOHKMFD_03707	5.93e-93	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
OPOHKMFD_03708	9.71e-48	-	-	-	-	-	-	-	-
OPOHKMFD_03709	3e-05	-	-	-	K	-	-	-	Helix-turn-helix domain
OPOHKMFD_03710	1.01e-21	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
OPOHKMFD_03712	4.37e-84	-	-	-	-	-	-	-	-
OPOHKMFD_03713	2.92e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
OPOHKMFD_03714	1.35e-61	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
OPOHKMFD_03715	1.56e-181	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
OPOHKMFD_03716	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
OPOHKMFD_03717	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OPOHKMFD_03718	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
OPOHKMFD_03719	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
OPOHKMFD_03720	8.73e-162	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OPOHKMFD_03721	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OPOHKMFD_03722	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OPOHKMFD_03723	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
OPOHKMFD_03724	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
OPOHKMFD_03726	1.1e-239	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OPOHKMFD_03727	1.41e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
OPOHKMFD_03728	3.98e-160	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
OPOHKMFD_03729	3.68e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
OPOHKMFD_03730	1.23e-227	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OPOHKMFD_03733	0.0	-	-	-	-	-	-	-	-
OPOHKMFD_03734	4.18e-232	-	-	-	L	-	-	-	Prophage endopeptidase tail
OPOHKMFD_03735	5.62e-131	-	-	-	S	-	-	-	Phage tail protein
OPOHKMFD_03736	2.9e-139	-	-	-	D	-	-	-	Phage tail tape measure protein
OPOHKMFD_03737	3.79e-42	-	-	-	-	-	-	-	-
OPOHKMFD_03738	1.57e-93	-	-	-	N	-	-	-	phage major tail protein, phi13 family
OPOHKMFD_03739	1.05e-33	-	-	-	-	-	-	-	-
OPOHKMFD_03741	1.02e-44	-	-	-	S	-	-	-	Phage head-tail joining protein
OPOHKMFD_03742	1.33e-34	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
OPOHKMFD_03743	3.55e-55	-	-	-	N	-	-	-	domain, Protein
OPOHKMFD_03744	3.44e-234	-	-	-	S	-	-	-	Phage capsid family
OPOHKMFD_03745	1.34e-156	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
OPOHKMFD_03746	2.73e-285	-	-	-	S	-	-	-	Phage portal protein
OPOHKMFD_03747	0.0	-	-	-	S	-	-	-	Terminase
OPOHKMFD_03748	1.2e-61	-	-	-	L	-	-	-	Phage terminase, small subunit
OPOHKMFD_03750	1.62e-40	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
OPOHKMFD_03752	4.7e-100	-	-	-	-	-	-	-	-
OPOHKMFD_03755	1.74e-07	-	-	-	-	-	-	-	-
OPOHKMFD_03758	2.79e-26	-	-	-	-	-	-	-	-
OPOHKMFD_03761	1.17e-45	-	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
OPOHKMFD_03762	6.18e-40	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
OPOHKMFD_03763	7.11e-69	-	-	-	S	-	-	-	Pfam:DUF867
OPOHKMFD_03764	8.56e-139	-	-	-	M	-	-	-	Right handed beta helix region
OPOHKMFD_03767	3.96e-62	-	-	-	-	-	-	-	-
OPOHKMFD_03768	2.1e-32	-	-	-	-	-	-	-	-
OPOHKMFD_03773	8.81e-12	-	-	-	-	-	-	-	-
OPOHKMFD_03776	1.55e-69	-	-	-	-	-	-	-	-
OPOHKMFD_03777	5.92e-55	-	-	-	K	-	-	-	Sigma-70, region 4
OPOHKMFD_03779	4.44e-92	-	-	-	H	-	-	-	dephospho-CoA kinase activity
OPOHKMFD_03780	2.32e-50	-	-	-	-	-	-	-	-
OPOHKMFD_03781	5.07e-91	-	-	-	S	-	-	-	SprT-like family
OPOHKMFD_03782	5.34e-45	-	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_03783	3.77e-146	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OPOHKMFD_03784	2.11e-77	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	deoxyuridine 5'-triphosphate nucleotidohydrolase
OPOHKMFD_03785	2.93e-196	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OPOHKMFD_03787	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OPOHKMFD_03788	2.68e-23	-	-	-	F	-	-	-	Belongs to the NrdI family
OPOHKMFD_03795	3.75e-212	-	-	-	-	-	-	-	-
OPOHKMFD_03796	1.31e-115	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
OPOHKMFD_03797	0.0	-	-	-	L	-	-	-	3'-5' exonuclease
OPOHKMFD_03800	1.34e-43	-	-	-	-	-	-	-	-
OPOHKMFD_03801	7.47e-119	-	-	-	-	-	-	-	-
OPOHKMFD_03807	1.05e-12	-	-	-	S	-	-	-	Cro/C1-type HTH DNA-binding domain
OPOHKMFD_03808	2.1e-07	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
OPOHKMFD_03809	3.27e-162	-	-	-	L	-	-	-	Toprim-like
OPOHKMFD_03810	1.49e-179	-	-	-	L	-	-	-	DnaB-like helicase C terminal domain
OPOHKMFD_03811	5.45e-13	yodN	-	-	-	-	-	-	-
OPOHKMFD_03812	6.18e-144	-	-	-	L	ko:K02315	-	ko00000,ko03032	DNA-dependent DNA replication
OPOHKMFD_03814	9e-72	-	-	-	-	-	-	-	-
OPOHKMFD_03816	4.16e-22	-	-	-	-	-	-	-	-
OPOHKMFD_03819	1.43e-47	-	-	-	-	-	-	-	-
OPOHKMFD_03823	5.12e-110	-	-	-	L	-	-	-	Phage integrase family
OPOHKMFD_03825	1.65e-118	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
OPOHKMFD_03826	7.86e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OPOHKMFD_03827	3.53e-171	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OPOHKMFD_03828	8.03e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
OPOHKMFD_03829	4.49e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
OPOHKMFD_03830	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
OPOHKMFD_03831	1.81e-41	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_03832	2.65e-102	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
OPOHKMFD_03833	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
OPOHKMFD_03834	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
OPOHKMFD_03835	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
OPOHKMFD_03836	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
OPOHKMFD_03837	6.56e-274	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
OPOHKMFD_03838	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OPOHKMFD_03839	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
OPOHKMFD_03840	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
OPOHKMFD_03841	3.02e-228	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
OPOHKMFD_03842	2.58e-179	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
OPOHKMFD_03843	1.81e-175	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
OPOHKMFD_03844	5.74e-129	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_03845	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OPOHKMFD_03846	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
OPOHKMFD_03847	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OPOHKMFD_03848	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
OPOHKMFD_03849	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
OPOHKMFD_03850	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OPOHKMFD_03851	8.48e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OPOHKMFD_03852	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OPOHKMFD_03853	1.81e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OPOHKMFD_03854	1.81e-170	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OPOHKMFD_03855	4.37e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
OPOHKMFD_03856	1.45e-259	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
OPOHKMFD_03857	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
OPOHKMFD_03858	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
OPOHKMFD_03859	2.07e-69	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase-like domain
OPOHKMFD_03860	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
OPOHKMFD_03861	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
OPOHKMFD_03862	6.34e-192	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
OPOHKMFD_03863	2.64e-216	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
OPOHKMFD_03864	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
OPOHKMFD_03865	7.5e-282	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
OPOHKMFD_03866	1.67e-184	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
OPOHKMFD_03867	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
OPOHKMFD_03868	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
OPOHKMFD_03869	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
OPOHKMFD_03870	9.92e-242	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
OPOHKMFD_03871	4.35e-262	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
OPOHKMFD_03872	3.26e-88	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
OPOHKMFD_03873	3.65e-59	ysdA	-	-	S	-	-	-	Membrane
OPOHKMFD_03874	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OPOHKMFD_03875	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
OPOHKMFD_03876	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OPOHKMFD_03878	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
OPOHKMFD_03879	8.47e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
OPOHKMFD_03880	1.96e-166	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
OPOHKMFD_03881	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
OPOHKMFD_03882	1.98e-189	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
OPOHKMFD_03883	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OPOHKMFD_03885	3.46e-205	ytxC	-	-	S	-	-	-	YtxC-like family
OPOHKMFD_03886	1.33e-141	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
OPOHKMFD_03887	1e-219	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
OPOHKMFD_03888	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
OPOHKMFD_03889	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OPOHKMFD_03890	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OPOHKMFD_03891	1.22e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OPOHKMFD_03892	1.15e-86	ytcD	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_03893	5.2e-258	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
OPOHKMFD_03894	4.54e-205	ytbE	-	-	S	-	-	-	reductase
OPOHKMFD_03895	4e-126	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OPOHKMFD_03896	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
OPOHKMFD_03897	4.05e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
OPOHKMFD_03898	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OPOHKMFD_03899	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
OPOHKMFD_03900	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPOHKMFD_03901	1.04e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
OPOHKMFD_03902	9.27e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
OPOHKMFD_03903	1.17e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
OPOHKMFD_03904	9.38e-95	ytwI	-	-	S	-	-	-	membrane
OPOHKMFD_03905	2.73e-245	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
OPOHKMFD_03906	3.16e-80	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
OPOHKMFD_03907	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
OPOHKMFD_03908	4.65e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
OPOHKMFD_03909	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
OPOHKMFD_03910	1.25e-207	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OPOHKMFD_03911	8.53e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
OPOHKMFD_03912	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
OPOHKMFD_03913	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
OPOHKMFD_03914	5.12e-112	ytrI	-	-	-	-	-	-	-
OPOHKMFD_03915	1.15e-39	-	-	-	-	-	-	-	-
OPOHKMFD_03916	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
OPOHKMFD_03917	1.24e-62	ytpI	-	-	S	-	-	-	YtpI-like protein
OPOHKMFD_03918	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
OPOHKMFD_03919	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
OPOHKMFD_03920	8.04e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OPOHKMFD_03922	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
OPOHKMFD_03923	3.03e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
OPOHKMFD_03924	9.5e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
OPOHKMFD_03925	3.85e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OPOHKMFD_03926	3.78e-224	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
OPOHKMFD_03927	1.12e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OPOHKMFD_03928	1.06e-94	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
OPOHKMFD_03929	8.34e-149	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
OPOHKMFD_03930	1.37e-110	yteJ	-	-	S	-	-	-	RDD family
OPOHKMFD_03931	8.34e-231	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
OPOHKMFD_03932	2.4e-189	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OPOHKMFD_03933	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
OPOHKMFD_03934	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OPOHKMFD_03935	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
OPOHKMFD_03936	6.26e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OPOHKMFD_03937	1.3e-264	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
OPOHKMFD_03938	8.23e-305	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
OPOHKMFD_03939	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OPOHKMFD_03940	5.29e-198	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
OPOHKMFD_03941	4.87e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_03942	3.24e-113	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
OPOHKMFD_03943	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
OPOHKMFD_03944	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OPOHKMFD_03945	2.47e-08	-	-	-	-	-	-	-	-
OPOHKMFD_03949	1.94e-137	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
OPOHKMFD_03950	4.91e-235	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
OPOHKMFD_03951	1.47e-85	-	-	-	S	-	-	-	Immunity protein 70
OPOHKMFD_03952	1.13e-144	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
OPOHKMFD_03953	1.54e-75	-	-	-	S	-	-	-	Bacteriophage holin family
OPOHKMFD_03977	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OPOHKMFD_03978	8.49e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OPOHKMFD_03979	3.72e-238	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
OPOHKMFD_03980	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
OPOHKMFD_03981	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
OPOHKMFD_03982	8.04e-101	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
OPOHKMFD_03983	2.59e-260	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
OPOHKMFD_03984	1.75e-276	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
OPOHKMFD_03985	2.82e-262	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
OPOHKMFD_03987	6.86e-296	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
OPOHKMFD_03988	5.23e-229	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
OPOHKMFD_03989	7.94e-308	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OPOHKMFD_03990	1.7e-196	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
OPOHKMFD_03991	3.53e-168	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
OPOHKMFD_03992	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
OPOHKMFD_03993	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OPOHKMFD_03994	6.65e-195	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
OPOHKMFD_03995	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OPOHKMFD_03996	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
OPOHKMFD_03997	5.81e-272	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
OPOHKMFD_03998	1.79e-215	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
OPOHKMFD_03999	1.97e-175	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
OPOHKMFD_04000	4.31e-295	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
OPOHKMFD_04001	9.24e-192	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
OPOHKMFD_04002	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
OPOHKMFD_04003	1.15e-238	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
OPOHKMFD_04004	1.03e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
OPOHKMFD_04005	1.44e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
OPOHKMFD_04006	1.27e-133	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
OPOHKMFD_04007	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
OPOHKMFD_04008	4.78e-95	ytkA	-	-	S	-	-	-	YtkA-like
OPOHKMFD_04010	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
OPOHKMFD_04011	3.2e-81	ytkC	-	-	S	-	-	-	Bacteriophage holin family
OPOHKMFD_04012	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
OPOHKMFD_04013	1.32e-183	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OPOHKMFD_04014	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
OPOHKMFD_04015	1.87e-240	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
OPOHKMFD_04016	5.48e-190	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
OPOHKMFD_04017	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
OPOHKMFD_04018	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OPOHKMFD_04019	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OPOHKMFD_04020	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
OPOHKMFD_04021	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
OPOHKMFD_04022	8.35e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OPOHKMFD_04023	4.7e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
OPOHKMFD_04024	4.81e-276	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
OPOHKMFD_04025	1.17e-133	ytqB	-	-	J	-	-	-	Putative rRNA methylase
OPOHKMFD_04026	2.35e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
OPOHKMFD_04027	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
OPOHKMFD_04029	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
OPOHKMFD_04030	5.96e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_04031	1.98e-214	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
OPOHKMFD_04032	1.37e-192	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
OPOHKMFD_04033	5.88e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_04034	1.39e-296	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
OPOHKMFD_04035	1.7e-165	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OPOHKMFD_04036	6.9e-234	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
OPOHKMFD_04037	1.56e-178	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
OPOHKMFD_04038	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
OPOHKMFD_04039	2.67e-76	yttA	-	-	S	-	-	-	Pfam Transposase IS66
OPOHKMFD_04040	2.45e-268	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
OPOHKMFD_04041	2.21e-182	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
OPOHKMFD_04042	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
OPOHKMFD_04043	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
OPOHKMFD_04044	4.98e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
OPOHKMFD_04045	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
OPOHKMFD_04046	7.65e-186	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
OPOHKMFD_04047	1.66e-214	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
OPOHKMFD_04048	8.99e-313	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
OPOHKMFD_04049	1.31e-243	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
OPOHKMFD_04050	2.66e-218	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
OPOHKMFD_04051	7.51e-178	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
OPOHKMFD_04052	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
OPOHKMFD_04053	2.58e-275	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OPOHKMFD_04054	2.68e-159	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OPOHKMFD_04055	2.53e-241	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OPOHKMFD_04056	1.06e-277	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
OPOHKMFD_04057	7.41e-177	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
OPOHKMFD_04058	4.17e-191	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
OPOHKMFD_04059	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
OPOHKMFD_04060	0.0	ytdP	-	-	K	-	-	-	Transcriptional regulator
OPOHKMFD_04061	1.31e-220	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
OPOHKMFD_04062	1.18e-278	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
OPOHKMFD_04063	6.78e-94	yteS	-	-	G	-	-	-	transport
OPOHKMFD_04064	0.0	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
OPOHKMFD_04065	3.13e-149	yteU	-	-	S	-	-	-	Integral membrane protein
OPOHKMFD_04066	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
OPOHKMFD_04067	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
OPOHKMFD_04068	5.74e-293	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
OPOHKMFD_04069	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OPOHKMFD_04070	2.49e-168	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
OPOHKMFD_04071	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
OPOHKMFD_04072	2.8e-168	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
OPOHKMFD_04073	4.99e-255	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
OPOHKMFD_04074	7.02e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
OPOHKMFD_04075	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
OPOHKMFD_04076	3e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
OPOHKMFD_04077	2.04e-128	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OPOHKMFD_04078	8.15e-211	ytlQ	-	-	-	-	-	-	-
OPOHKMFD_04079	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
OPOHKMFD_04080	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
OPOHKMFD_04081	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
OPOHKMFD_04082	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
OPOHKMFD_04083	8.79e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
OPOHKMFD_04084	1.3e-191	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
OPOHKMFD_04085	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
OPOHKMFD_04086	3.34e-67	ytzB	-	-	S	-	-	-	small secreted protein
OPOHKMFD_04087	3.71e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
OPOHKMFD_04088	7.02e-103	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
OPOHKMFD_04089	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
OPOHKMFD_04090	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
OPOHKMFD_04091	1.03e-139	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OPOHKMFD_04092	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
OPOHKMFD_04093	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
OPOHKMFD_04094	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OPOHKMFD_04095	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
OPOHKMFD_04096	2.23e-71	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
OPOHKMFD_04097	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
OPOHKMFD_04098	4.16e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
OPOHKMFD_04099	6.84e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
OPOHKMFD_04100	1.6e-161	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
OPOHKMFD_04101	1.81e-290	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
OPOHKMFD_04102	6.16e-152	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
OPOHKMFD_04103	2.43e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
OPOHKMFD_04104	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OPOHKMFD_04105	5.31e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OPOHKMFD_04107	3.83e-202	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
OPOHKMFD_04108	9.97e-59	-	-	-	E	-	-	-	IrrE N-terminal-like domain
OPOHKMFD_04109	1.05e-18	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	sequence-specific DNA binding
OPOHKMFD_04111	7.96e-41	-	-	-	-	-	-	-	-
OPOHKMFD_04114	3.31e-26	-	-	-	-	-	-	-	-
OPOHKMFD_04115	1.42e-101	-	-	-	S	ko:K07741	-	ko00000	Phage regulatory protein Rha (Phage_pRha)
OPOHKMFD_04118	2.7e-128	-	-	-	L	-	-	-	DnaD domain protein
OPOHKMFD_04119	9.77e-18	-	-	-	S	-	-	-	Loader and inhibitor of phage G40P
OPOHKMFD_04120	5.4e-211	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	replicative DNA helicase
OPOHKMFD_04121	7.58e-31	-	-	-	-	-	-	-	-
OPOHKMFD_04122	3.01e-12	-	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
OPOHKMFD_04123	4.9e-66	-	-	-	M	-	-	-	ArpU family transcriptional regulator
OPOHKMFD_04131	5.07e-14	-	-	-	-	-	-	-	-
OPOHKMFD_04133	6.88e-66	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
OPOHKMFD_04134	6.85e-103	-	-	-	L	-	-	-	phage terminase small subunit
OPOHKMFD_04135	0.0	-	-	-	S	-	-	-	Terminase
OPOHKMFD_04137	2.64e-303	-	-	-	S	-	-	-	Phage portal protein
OPOHKMFD_04138	6.14e-151	-	-	-	OU	-	-	-	Belongs to the peptidase S14 family
OPOHKMFD_04139	1.06e-266	-	-	-	S	-	-	-	capsid protein
OPOHKMFD_04140	1.89e-34	-	-	-	-	-	-	-	-
OPOHKMFD_04141	1.4e-50	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
OPOHKMFD_04142	2.13e-51	-	-	-	S	-	-	-	Phage head-tail joining protein
OPOHKMFD_04143	1.19e-66	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
OPOHKMFD_04145	2.65e-100	-	-	-	S	-	-	-	Phage tail tube protein
OPOHKMFD_04148	0.0	-	-	-	D	-	-	-	phage tail tape measure protein
OPOHKMFD_04149	1.19e-135	-	-	-	S	-	-	-	Phage tail protein
OPOHKMFD_04150	2.88e-277	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
OPOHKMFD_04151	0.0	-	-	-	-	-	-	-	-
OPOHKMFD_04152	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
OPOHKMFD_04153	2.36e-74	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
OPOHKMFD_04154	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
OPOHKMFD_04155	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
OPOHKMFD_04156	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OPOHKMFD_04157	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OPOHKMFD_04158	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
OPOHKMFD_04159	4.29e-161	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
OPOHKMFD_04160	6.35e-113	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
OPOHKMFD_04161	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OPOHKMFD_04162	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
OPOHKMFD_04163	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
OPOHKMFD_04164	2.04e-95	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OPOHKMFD_04165	3.52e-173	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OPOHKMFD_04166	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
OPOHKMFD_04167	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
OPOHKMFD_04168	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
OPOHKMFD_04169	1.19e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
OPOHKMFD_04170	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OPOHKMFD_04171	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OPOHKMFD_04172	3.31e-103	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OPOHKMFD_04173	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
OPOHKMFD_04174	5.1e-140	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
OPOHKMFD_04175	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OPOHKMFD_04176	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OPOHKMFD_04177	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
OPOHKMFD_04178	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OPOHKMFD_04179	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
OPOHKMFD_04180	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OPOHKMFD_04181	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OPOHKMFD_04182	2.13e-229	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
OPOHKMFD_04183	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
OPOHKMFD_04184	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OPOHKMFD_04185	7.98e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
OPOHKMFD_04186	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
OPOHKMFD_04187	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OPOHKMFD_04188	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OPOHKMFD_04189	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OPOHKMFD_04190	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OPOHKMFD_04191	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OPOHKMFD_04192	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
OPOHKMFD_04193	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OPOHKMFD_04194	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OPOHKMFD_04195	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OPOHKMFD_04196	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OPOHKMFD_04197	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OPOHKMFD_04198	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OPOHKMFD_04199	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OPOHKMFD_04200	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OPOHKMFD_04201	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OPOHKMFD_04202	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
OPOHKMFD_04203	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
OPOHKMFD_04204	8.09e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
OPOHKMFD_04205	2.51e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
OPOHKMFD_04206	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
OPOHKMFD_04207	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OPOHKMFD_04208	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
OPOHKMFD_04209	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OPOHKMFD_04210	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OPOHKMFD_04211	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OPOHKMFD_04212	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
OPOHKMFD_04213	7.5e-200	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OPOHKMFD_04214	6.34e-196	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OPOHKMFD_04215	1.6e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OPOHKMFD_04216	4.33e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
OPOHKMFD_04217	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OPOHKMFD_04218	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
OPOHKMFD_04219	1.69e-183	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
OPOHKMFD_04220	1.47e-90	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
OPOHKMFD_04221	1.23e-167	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
OPOHKMFD_04222	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
OPOHKMFD_04223	1.48e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
OPOHKMFD_04224	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
OPOHKMFD_04225	8.69e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
OPOHKMFD_04226	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
OPOHKMFD_04227	2.7e-132	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
OPOHKMFD_04228	8.37e-259	yaaN	-	-	P	-	-	-	Belongs to the TelA family
OPOHKMFD_04229	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
OPOHKMFD_04230	1.63e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OPOHKMFD_04231	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_04232	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
OPOHKMFD_04233	9.28e-230	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
OPOHKMFD_04234	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
OPOHKMFD_04235	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
OPOHKMFD_04236	3.28e-177	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
OPOHKMFD_04237	9.89e-64	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
OPOHKMFD_04238	2.95e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OPOHKMFD_04239	4.32e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
OPOHKMFD_04240	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OPOHKMFD_04241	5.9e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
OPOHKMFD_04242	5.57e-276	yabE	-	-	T	-	-	-	protein conserved in bacteria
OPOHKMFD_04243	3.36e-124	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OPOHKMFD_04244	2.05e-198	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
OPOHKMFD_04245	1.11e-198	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
OPOHKMFD_04246	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
OPOHKMFD_04247	3.96e-37	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
OPOHKMFD_04248	2.34e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OPOHKMFD_04249	4.66e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
OPOHKMFD_04250	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
OPOHKMFD_04251	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
OPOHKMFD_04252	2.58e-309	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OPOHKMFD_04253	1.22e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OPOHKMFD_04254	1.45e-136	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OPOHKMFD_04255	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
OPOHKMFD_04256	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
OPOHKMFD_04257	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OPOHKMFD_04258	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
OPOHKMFD_04259	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OPOHKMFD_04260	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
OPOHKMFD_04261	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
OPOHKMFD_04262	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
OPOHKMFD_04263	1.49e-137	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
OPOHKMFD_04264	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
OPOHKMFD_04265	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
OPOHKMFD_04268	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
OPOHKMFD_04269	1.61e-167	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
OPOHKMFD_04270	1.2e-236	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
OPOHKMFD_04271	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
OPOHKMFD_04272	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
OPOHKMFD_04273	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OPOHKMFD_04274	8.08e-188	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OPOHKMFD_04275	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OPOHKMFD_04276	2.07e-205	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
OPOHKMFD_04277	1.54e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
OPOHKMFD_04278	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OPOHKMFD_04279	4.92e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
OPOHKMFD_04280	1.32e-215	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
OPOHKMFD_04281	1.11e-203	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OPOHKMFD_04282	3.8e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OPOHKMFD_04283	4.56e-115	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OPOHKMFD_04284	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
OPOHKMFD_04285	1.59e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OPOHKMFD_04286	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
OPOHKMFD_04287	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
OPOHKMFD_04288	9.82e-101	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Catalyzes the reduction of arsenate As(V) to arsenite As(III)
OPOHKMFD_04289	7.13e-233	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Arsenic resistance protein
OPOHKMFD_04290	2.56e-104	cadI	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OPOHKMFD_04291	1.53e-72	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	ArsR family transcriptional regulator
OPOHKMFD_04292	5.5e-193	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
OPOHKMFD_04293	8.68e-120	-	-	-	S	-	-	-	Tetratricopeptide repeat
OPOHKMFD_04296	0.0	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
OPOHKMFD_04297	1.66e-136	-	-	-	S	ko:K21492	-	ko00000,ko02048	Suppressor of fused protein (SUFU)
OPOHKMFD_04299	5.4e-80	-	-	-	-	-	-	-	-
OPOHKMFD_04301	1.27e-182	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
OPOHKMFD_04302	8.36e-89	-	-	-	S	-	-	-	Bacteriophage holin family
OPOHKMFD_04303	1.36e-210	xepA	-	-	-	-	-	-	-
OPOHKMFD_04304	2.51e-28	-	-	-	-	-	-	-	-
OPOHKMFD_04305	1.38e-71	xkdW	-	-	S	-	-	-	XkdW protein
OPOHKMFD_04306	2.96e-246	-	-	-	-	-	-	-	-
OPOHKMFD_04307	4.62e-49	-	-	-	-	-	-	-	-
OPOHKMFD_04308	2.74e-126	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
OPOHKMFD_04309	6.67e-239	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
OPOHKMFD_04310	6.6e-91	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
OPOHKMFD_04311	8.16e-42	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
OPOHKMFD_04312	8.96e-226	xkdQ	-	-	G	-	-	-	NLP P60 protein
OPOHKMFD_04313	6.29e-154	xkdP	-	-	S	-	-	-	Lysin motif
OPOHKMFD_04314	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
OPOHKMFD_04315	1.12e-23	-	-	-	-	-	-	-	-
OPOHKMFD_04316	1.27e-89	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
OPOHKMFD_04317	4.23e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
OPOHKMFD_04318	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
OPOHKMFD_04319	1.21e-34	-	-	-	-	-	-	-	-
OPOHKMFD_04320	1.48e-98	yqbJ	-	-	-	-	-	-	-
OPOHKMFD_04321	8.84e-113	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
OPOHKMFD_04322	3.38e-83	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
OPOHKMFD_04323	1.43e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF3199)
OPOHKMFD_04324	2.12e-60	-	-	-	S	-	-	-	YqbF, hypothetical protein domain
OPOHKMFD_04325	7.57e-215	xkdG	-	-	S	-	-	-	Phage capsid family
OPOHKMFD_04326	4.23e-158	yqbD	-	-	L	-	-	-	Putative phage serine protease XkdF
OPOHKMFD_04327	5.03e-90	-	-	-	S	-	-	-	Phage Mu protein F like protein
OPOHKMFD_04328	3.89e-177	-	-	-	S	-	-	-	Phage Mu protein F like protein
OPOHKMFD_04329	1.39e-306	yqbA	-	-	S	-	-	-	portal protein
OPOHKMFD_04330	2.96e-13	yqbA	-	-	S	-	-	-	portal protein
OPOHKMFD_04331	3.38e-315	yqaT	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
OPOHKMFD_04332	7.73e-147	yqaS	-	-	L	-	-	-	DNA packaging
OPOHKMFD_04334	2.83e-99	yqaQ	-	-	L	-	-	-	Transposase
OPOHKMFD_04336	8.38e-42	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
OPOHKMFD_04337	1.28e-93	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
OPOHKMFD_04339	5.04e-207	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
OPOHKMFD_04340	5.29e-156	yqaL	-	-	L	-	-	-	DnaD domain protein
OPOHKMFD_04341	2.79e-192	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
OPOHKMFD_04342	3.18e-213	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
OPOHKMFD_04346	1.04e-133	-	-	-	-	-	-	-	-
OPOHKMFD_04348	3.43e-49	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
OPOHKMFD_04349	1.25e-74	-	-	-	K	-	-	-	sequence-specific DNA binding
OPOHKMFD_04351	8.73e-132	yqaC	-	-	F	-	-	-	adenylate kinase activity
OPOHKMFD_04352	1.58e-122	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
OPOHKMFD_04353	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
OPOHKMFD_04354	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
OPOHKMFD_04355	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OPOHKMFD_04356	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OPOHKMFD_04357	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OPOHKMFD_04358	2.88e-106	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
OPOHKMFD_04359	5.64e-125	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
OPOHKMFD_04360	4.25e-275	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
OPOHKMFD_04361	8.15e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
OPOHKMFD_04362	3.06e-158	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
OPOHKMFD_04364	9.79e-296	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OPOHKMFD_04365	1.66e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OPOHKMFD_04366	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OPOHKMFD_04367	3.75e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
OPOHKMFD_04368	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
OPOHKMFD_04369	2.05e-230	yaaC	-	-	S	-	-	-	YaaC-like Protein
OPOHKMFD_04370	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
OPOHKMFD_04387	3.71e-31	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)