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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
BIGFKLDO_00001	1.81e-149	cobH	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_00002	0.0	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
BIGFKLDO_00003	8.03e-234	cobD_2	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_00004	5.76e-217	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BIGFKLDO_00005	1.66e-144	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_00006	3.85e-72	-	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
BIGFKLDO_00007	8.01e-175	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BIGFKLDO_00008	2.81e-112	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	adenosylcobinamide kinase adenosylcobinamide-phosphate guanylyltransferase
BIGFKLDO_00009	5.27e-239	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
BIGFKLDO_00010	6.38e-314	cbiA	6.3.5.11, 6.3.5.9	-	H	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
BIGFKLDO_00011	7.91e-270	cbiT	2.1.1.132, 2.1.1.196	-	H	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit
BIGFKLDO_00012	4.24e-163	cobK	1.3.1.106, 1.3.1.54, 1.3.1.76, 4.99.1.4	-	H	ko:K02304,ko:K05895	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	reductase
BIGFKLDO_00013	3.56e-185	cobJ	2.1.1.131, 2.1.1.272	-	H	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-3B
BIGFKLDO_00014	1.62e-231	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
BIGFKLDO_00015	3.54e-179	cobM	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	precorrin-4 C11-methyltransferase
BIGFKLDO_00016	0.0	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BIGFKLDO_00017	4.2e-221	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BIGFKLDO_00018	1.17e-271	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
BIGFKLDO_00019	3.45e-180	-	-	-	HP	-	-	-	small periplasmic lipoprotein
BIGFKLDO_00020	4.67e-264	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_00021	1.9e-172	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
BIGFKLDO_00022	0.0	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
BIGFKLDO_00023	7.62e-171	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
BIGFKLDO_00024	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, C-terminal domain
BIGFKLDO_00025	3.52e-311	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family
BIGFKLDO_00026	1.78e-244	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00027	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
BIGFKLDO_00028	1.17e-115	-	-	-	S	-	-	-	TIGRFAM C_GCAxxG_C_C family
BIGFKLDO_00029	1.02e-190	-	-	-	I	-	-	-	alpha/beta hydrolase fold
BIGFKLDO_00030	2.21e-100	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
BIGFKLDO_00031	5.09e-129	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
BIGFKLDO_00032	6.2e-129	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	acetyltransferase (GNAT) family
BIGFKLDO_00033	3.45e-265	-	-	-	I	-	-	-	alpha/beta hydrolase fold
BIGFKLDO_00034	1.24e-224	-	-	-	E	-	-	-	Transglutaminase-like superfamily
BIGFKLDO_00035	5.19e-269	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
BIGFKLDO_00036	7.24e-284	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00038	5.41e-285	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
BIGFKLDO_00039	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BIGFKLDO_00040	4.64e-132	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
BIGFKLDO_00041	9.75e-315	ynbB	-	-	P	-	-	-	Cystathionine beta-lyase family protein involved in aluminum resistance
BIGFKLDO_00042	1.37e-99	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
BIGFKLDO_00043	7.08e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BIGFKLDO_00044	1.1e-184	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BIGFKLDO_00045	6.84e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BIGFKLDO_00046	6.19e-107	-	-	-	K	-	-	-	dihydroxyacetone kinase regulator
BIGFKLDO_00047	0.0	-	-	-	C	-	-	-	Radical SAM domain protein
BIGFKLDO_00048	2.51e-31	-	-	-	-	-	-	-	-
BIGFKLDO_00049	4.66e-266	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00050	0.0	cat	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
BIGFKLDO_00051	4.65e-123	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BIGFKLDO_00052	1.65e-286	thlA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
BIGFKLDO_00053	5.43e-183	crt	4.2.1.17	-	I	ko:K01715	ko00650,ko01200,map00650,map01200	ko00000,ko00001,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
BIGFKLDO_00054	6.21e-208	hbd	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
BIGFKLDO_00055	3.01e-274	bcd	1.3.8.1	-	C	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	Acyl-CoA dehydrogenase, C-terminal domain
BIGFKLDO_00056	3.16e-188	-	1.3.1.108	-	C	ko:K03521,ko:K22431	-	ko00000,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_00057	1.51e-259	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
BIGFKLDO_00058	2.38e-223	-	-	-	M	-	-	-	Cysteine-rich secretory protein family
BIGFKLDO_00059	2.47e-129	yvyE	-	-	S	-	-	-	YigZ family
BIGFKLDO_00060	7.82e-239	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the dGTPase family. Type 2 subfamily
BIGFKLDO_00061	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
BIGFKLDO_00062	1.07e-241	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
BIGFKLDO_00063	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BIGFKLDO_00064	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BIGFKLDO_00065	3.02e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BIGFKLDO_00066	1.14e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
BIGFKLDO_00067	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BIGFKLDO_00068	1.48e-291	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BIGFKLDO_00069	1.76e-258	-	2.8.1.7	-	H	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	aminotransferase class V
BIGFKLDO_00070	2.49e-310	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_00071	3.67e-131	rbr3A	-	-	C	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00072	0.0	copA	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
BIGFKLDO_00073	8.96e-79	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
BIGFKLDO_00074	5.07e-188	-	-	-	S	-	-	-	Putative esterase
BIGFKLDO_00075	1.08e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF4250)
BIGFKLDO_00076	1.85e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
BIGFKLDO_00077	1.06e-157	-	-	-	S	-	-	-	peptidase M50
BIGFKLDO_00078	1.19e-135	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BIGFKLDO_00079	4.64e-124	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BIGFKLDO_00080	2.05e-148	-	-	-	-	-	-	-	-
BIGFKLDO_00081	2.54e-87	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
BIGFKLDO_00082	3.01e-187	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
BIGFKLDO_00083	4.24e-292	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
BIGFKLDO_00084	6.13e-174	-	-	-	K	-	-	-	LytTr DNA-binding domain
BIGFKLDO_00085	1.38e-309	-	-	-	T	-	-	-	Histidine kinase
BIGFKLDO_00086	4.43e-100	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
BIGFKLDO_00087	3.13e-224	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
BIGFKLDO_00088	5e-174	-	-	-	K	ko:K03710	-	ko00000,ko03000	Psort location Cytoplasmic, score
BIGFKLDO_00089	6.35e-126	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
BIGFKLDO_00090	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
BIGFKLDO_00091	1.56e-181	thyX	2.1.1.148	-	H	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	ko00000,ko00001,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
BIGFKLDO_00092	3.17e-163	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	thymidylate kinase
BIGFKLDO_00093	7.44e-190	-	-	-	-	-	-	-	-
BIGFKLDO_00094	8.49e-265	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BIGFKLDO_00095	3.08e-308	yhbU_1	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
BIGFKLDO_00096	5.68e-118	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00097	3.55e-99	-	-	-	C	-	-	-	Flavodoxin
BIGFKLDO_00098	2.31e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
BIGFKLDO_00099	7.56e-148	-	-	-	S	ko:K07025	-	ko00000	IA, variant 3
BIGFKLDO_00100	1.04e-64	-	-	-	S	-	-	-	sporulation protein, YlmC YmxH family
BIGFKLDO_00101	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00102	2.77e-161	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
BIGFKLDO_00103	1.78e-211	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BIGFKLDO_00104	2.61e-207	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
BIGFKLDO_00105	3.81e-268	-	-	-	I	-	-	-	Carboxyl transferase domain
BIGFKLDO_00106	1.09e-33	gcdC	-	-	I	-	-	-	Biotin-requiring enzyme
BIGFKLDO_00107	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Pyruvate carboxylase, C-terminal domain subunit K01960
BIGFKLDO_00108	1.66e-73	-	-	-	S	-	-	-	Helix-turn-helix of DDE superfamily endonuclease
BIGFKLDO_00109	7.15e-199	yicC	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00110	5.98e-55	NPD7_560	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
BIGFKLDO_00111	1.04e-129	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
BIGFKLDO_00112	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BIGFKLDO_00113	6.9e-129	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
BIGFKLDO_00114	5.42e-226	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BIGFKLDO_00115	8.57e-306	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BIGFKLDO_00116	4.97e-249	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BIGFKLDO_00117	1.45e-181	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	serine threonine protein phosphatase
BIGFKLDO_00118	0.0	prkC	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
BIGFKLDO_00119	4.56e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
BIGFKLDO_00120	1.35e-149	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
BIGFKLDO_00121	0.0	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00122	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BIGFKLDO_00123	2.4e-113	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
BIGFKLDO_00125	1.78e-30	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
BIGFKLDO_00127	1.92e-240	spoIIIAE	-	-	S	ko:K06394	-	ko00000	Stage III sporulation protein AE (spore_III_AE)
BIGFKLDO_00129	4.16e-61	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
BIGFKLDO_00130	1.84e-120	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
BIGFKLDO_00131	4.91e-78	asp	-	-	S	-	-	-	Asp23 family, cell envelope-related function
BIGFKLDO_00132	9.59e-101	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BIGFKLDO_00133	1.4e-166	gcp1	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BIGFKLDO_00134	2.32e-208	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BIGFKLDO_00135	7e-36	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BIGFKLDO_00136	1.98e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
BIGFKLDO_00137	1.39e-101	-	-	-	S	ko:K09775	-	ko00000	Divergent PAP2 family
BIGFKLDO_00138	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BIGFKLDO_00139	8.86e-176	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
BIGFKLDO_00140	3.18e-202	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BIGFKLDO_00141	6.8e-110	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
BIGFKLDO_00142	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
BIGFKLDO_00143	1.1e-296	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BIGFKLDO_00144	2.36e-130	ptbA	-	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system
BIGFKLDO_00145	1.9e-99	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
BIGFKLDO_00146	2.38e-310	capA	-	-	M	ko:K07282	-	ko00000	Capsule synthesis protein
BIGFKLDO_00147	2.22e-182	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
BIGFKLDO_00148	7.01e-213	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BIGFKLDO_00149	1.53e-266	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartate-semialdehyde dehydrogenase family
BIGFKLDO_00150	1.43e-249	queA	2.4.99.17	-	H	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BIGFKLDO_00151	4.55e-290	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
BIGFKLDO_00152	5.34e-64	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase, YajC subunit
BIGFKLDO_00155	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BIGFKLDO_00156	3.74e-284	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
BIGFKLDO_00157	8.73e-131	-	-	-	M	-	-	-	N-acetylmuramoyl-L-alanine amidase
BIGFKLDO_00158	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
BIGFKLDO_00159	1.56e-176	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
BIGFKLDO_00161	1.09e-199	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BIGFKLDO_00162	1.95e-114	ybeY	3.5.4.5	-	S	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BIGFKLDO_00163	6.24e-212	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein
BIGFKLDO_00164	1.17e-67	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
BIGFKLDO_00165	9.97e-119	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
BIGFKLDO_00167	2.69e-188	-	-	-	S	ko:K07402	-	ko00000	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
BIGFKLDO_00168	1.77e-240	-	-	-	O	ko:K07402	-	ko00000	XdhC and CoxI family
BIGFKLDO_00169	2.5e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF3343)
BIGFKLDO_00170	1.43e-208	csd	-	-	E	-	-	-	cysteine desulfurase family protein
BIGFKLDO_00171	1.45e-136	yedF	-	-	O	ko:K04085	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	DsrE/DsrF-like family
BIGFKLDO_00172	4.73e-242	selD	2.7.9.3	-	H	ko:K01008	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000,ko03016	Synthesizes selenophosphate from selenide and ATP
BIGFKLDO_00173	9.75e-163	yqeC	-	-	H	-	-	-	selenium-dependent hydroxylase accessory protein YqeC
BIGFKLDO_00174	0.0	xdhD	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00175	2.6e-111	hcrC	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	[2Fe-2S] binding domain
BIGFKLDO_00176	1.08e-176	-	-	-	C	-	-	-	FAD binding domain in molybdopterin dehydrogenase
BIGFKLDO_00177	1.36e-137	ygfJ	2.7.7.76	-	S	ko:K07141	ko00790,map00790	ko00000,ko00001,ko01000	MobA-like NTP transferase domain
BIGFKLDO_00178	1.2e-301	pbuX	-	-	F	ko:K03458	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_00179	5.77e-182	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
BIGFKLDO_00180	3.04e-59	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
BIGFKLDO_00181	2.65e-152	-	-	-	E	-	-	-	AzlC protein
BIGFKLDO_00182	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
BIGFKLDO_00183	5.91e-75	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00184	2.45e-47	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00185	3.56e-86	-	-	-	S	-	-	-	YjbR
BIGFKLDO_00186	2.6e-233	pfkA	2.7.1.11	-	H	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
BIGFKLDO_00187	0.0	dnaE	2.7.7.7	-	L	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
BIGFKLDO_00188	8.52e-216	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
BIGFKLDO_00189	4.38e-186	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
BIGFKLDO_00190	4.57e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
BIGFKLDO_00191	3.35e-218	hprK	-	-	H	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BIGFKLDO_00192	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Na Pi-cotransporter II-like protein
BIGFKLDO_00193	1.13e-154	phoB	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator receiver domain protein
BIGFKLDO_00194	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
BIGFKLDO_00197	0.0	-	-	-	EG	ko:K06295	-	ko00000	spore germination protein
BIGFKLDO_00198	2.86e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
BIGFKLDO_00200	4.32e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BIGFKLDO_00201	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BIGFKLDO_00202	0.0	-	-	-	EK	-	-	-	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
BIGFKLDO_00203	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BIGFKLDO_00204	3.34e-139	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
BIGFKLDO_00205	1.9e-295	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
BIGFKLDO_00206	5.89e-161	-	-	-	S	ko:K07099	-	ko00000	Ser Thr phosphatase family protein
BIGFKLDO_00207	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
BIGFKLDO_00208	2.18e-80	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
BIGFKLDO_00209	1.63e-152	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BIGFKLDO_00210	5.17e-220	ylqF	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BIGFKLDO_00211	3.25e-125	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
BIGFKLDO_00212	6.76e-73	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
BIGFKLDO_00213	1.42e-132	-	-	-	S	-	-	-	Radical SAM-linked protein
BIGFKLDO_00214	0.0	-	-	-	C	-	-	-	Radical SAM domain protein
BIGFKLDO_00215	1.06e-105	-	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Peptidase M50
BIGFKLDO_00216	8.66e-113	-	-	-	M	-	-	-	Peptidase family M23
BIGFKLDO_00217	0.0	ppk	2.7.4.1	-	H	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BIGFKLDO_00218	9.19e-76	-	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
BIGFKLDO_00219	2.12e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
BIGFKLDO_00220	1.89e-228	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
BIGFKLDO_00221	4.97e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BIGFKLDO_00222	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BIGFKLDO_00223	5.01e-135	-	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
BIGFKLDO_00224	5.69e-195	-	-	-	S	-	-	-	S4 domain protein
BIGFKLDO_00225	3.29e-104	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
BIGFKLDO_00226	2.78e-308	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BIGFKLDO_00227	4.03e-178	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BIGFKLDO_00228	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BIGFKLDO_00229	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BIGFKLDO_00230	1.79e-92	-	-	-	S	-	-	-	Belongs to the UPF0342 family
BIGFKLDO_00231	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BIGFKLDO_00232	7.02e-94	-	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
BIGFKLDO_00233	4.76e-307	yrvN	-	-	L	ko:K07478	-	ko00000	ATPase, AAA family
BIGFKLDO_00234	1.29e-165	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BIGFKLDO_00235	8.09e-33	-	-	-	S	-	-	-	Transglycosylase associated protein
BIGFKLDO_00237	1.53e-89	-	-	-	-	-	-	-	-
BIGFKLDO_00238	3.61e-214	dnaD	-	-	-	ko:K02086	-	ko00000	-
BIGFKLDO_00239	1.36e-220	dnaC	-	-	L	ko:K02315	-	ko00000,ko03032	DNA replication protein
BIGFKLDO_00240	8.08e-190	yycJ	-	-	S	-	-	-	Metallo-beta-lactamase domain protein
BIGFKLDO_00241	4.77e-289	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BIGFKLDO_00242	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
BIGFKLDO_00243	5.64e-227	PflX	1.97.1.4	-	C	ko:K04070	-	ko00000,ko01000	pyruvate formate lyase activating
BIGFKLDO_00244	5.86e-116	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	to two-component sensor histidine kinase YesN
BIGFKLDO_00245	1.33e-252	-	-	-	S	-	-	-	Glycosyl hydrolase family 115
BIGFKLDO_00246	5.51e-126	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
BIGFKLDO_00247	3.11e-140	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
BIGFKLDO_00248	2.41e-170	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
BIGFKLDO_00249	9.97e-96	-	-	-	KT	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Psort location Cytoplasmic, score 9.98
BIGFKLDO_00250	5.18e-57	-	-	-	M	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
BIGFKLDO_00251	7.38e-214	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
BIGFKLDO_00252	2.94e-47	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00253	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
BIGFKLDO_00254	8.43e-317	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00255	9.37e-159	metH2	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Vitamin B12 dependent methionine synthase activation
BIGFKLDO_00256	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_00257	2.65e-15	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	K02342 DNA polymerase III subunit epsilon
BIGFKLDO_00258	9.07e-143	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
BIGFKLDO_00259	3.55e-154	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
BIGFKLDO_00260	1.29e-238	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CRISPR system CASCADE complex protein CasC
BIGFKLDO_00261	1.46e-145	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
BIGFKLDO_00262	0.0	casA	-	-	L	ko:K19123	-	ko00000,ko02048	CRISPR system CASCADE complex protein CasA
BIGFKLDO_00263	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase, Cas3
BIGFKLDO_00264	7.67e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
BIGFKLDO_00266	0.0	-	-	-	S	-	-	-	Domain of unknown function DUF87
BIGFKLDO_00267	1.25e-179	-	-	-	L	ko:K07126	-	ko00000	Sel1-like repeats.
BIGFKLDO_00268	3.36e-114	-	-	-	K	-	-	-	WYL domain
BIGFKLDO_00270	3.56e-233	-	-	-	-	-	-	-	-
BIGFKLDO_00271	0.0	-	-	-	S	-	-	-	COG0433 Predicted ATPase
BIGFKLDO_00272	1.75e-229	-	-	-	-	-	-	-	-
BIGFKLDO_00273	8.59e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF4869)
BIGFKLDO_00274	5.25e-298	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00275	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00276	1.57e-150	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
BIGFKLDO_00277	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00278	7.5e-202	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00279	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
BIGFKLDO_00280	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
BIGFKLDO_00281	3.56e-195	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
BIGFKLDO_00283	3.71e-169	-	-	-	S	-	-	-	RloB-like protein
BIGFKLDO_00284	5.84e-294	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
BIGFKLDO_00285	4.76e-160	ddpX	3.4.13.22	-	-	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-
BIGFKLDO_00287	3.96e-310	-	-	-	S	-	-	-	Double zinc ribbon
BIGFKLDO_00288	7.99e-75	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
BIGFKLDO_00290	2.22e-163	-	-	-	L	-	-	-	Resolvase, N terminal domain
BIGFKLDO_00291	4.66e-88	-	-	-	-	-	-	-	-
BIGFKLDO_00292	9.08e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF1071)
BIGFKLDO_00293	1.74e-224	-	-	-	L	-	-	-	YqaJ viral recombinase family
BIGFKLDO_00295	1.68e-227	-	-	-	S	-	-	-	Domain of unknown function (DUF932)
BIGFKLDO_00297	0.0	-	-	-	L	-	-	-	Resolvase, N terminal domain
BIGFKLDO_00299	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase P4 family
BIGFKLDO_00302	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
BIGFKLDO_00303	7.69e-142	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BIGFKLDO_00305	5.17e-140	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
BIGFKLDO_00306	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BIGFKLDO_00307	5.91e-229	-	-	-	-	-	-	-	-
BIGFKLDO_00308	0.0	-	-	-	S	-	-	-	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BIGFKLDO_00309	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
BIGFKLDO_00310	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_00311	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
BIGFKLDO_00312	8.99e-114	-	-	-	K	-	-	-	MarR family
BIGFKLDO_00313	1.94e-215	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
BIGFKLDO_00314	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
BIGFKLDO_00315	3.73e-237	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
BIGFKLDO_00316	7.17e-109	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
BIGFKLDO_00317	5.96e-304	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
BIGFKLDO_00318	2.55e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
BIGFKLDO_00319	1.08e-218	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
BIGFKLDO_00320	7.06e-249	-	-	-	S	-	-	-	Nitronate monooxygenase
BIGFKLDO_00321	1.25e-213	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Psort location Cytoplasmic, score
BIGFKLDO_00322	3.57e-211	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BIGFKLDO_00323	5.43e-228	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
BIGFKLDO_00324	9.52e-205	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BIGFKLDO_00325	3.48e-44	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BIGFKLDO_00326	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BIGFKLDO_00327	8.2e-315	-	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
BIGFKLDO_00328	2.73e-263	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BIGFKLDO_00329	9.47e-284	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_00330	1.57e-97	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BIGFKLDO_00331	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
BIGFKLDO_00332	0.0	spoVD	3.4.16.4	-	M	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein
BIGFKLDO_00333	4.43e-100	-	-	-	-	-	-	-	-
BIGFKLDO_00334	3.82e-229	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
BIGFKLDO_00335	3.36e-46	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
BIGFKLDO_00336	2.81e-75	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00337	1.59e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
BIGFKLDO_00338	2.25e-150	-	-	-	C	-	-	-	NADPH-dependent FMN reductase
BIGFKLDO_00339	0.0	lacZ	3.2.1.23, 3.2.1.31	-	G	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
BIGFKLDO_00340	8.61e-89	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
BIGFKLDO_00341	4.76e-212	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00342	4.76e-159	-	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	Psort location Cytoplasmic, score
BIGFKLDO_00343	1.07e-60	-	-	-	-	-	-	-	-
BIGFKLDO_00344	6.38e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
BIGFKLDO_00345	3.65e-149	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_00346	1.19e-154	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
BIGFKLDO_00347	4.72e-160	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00348	6.98e-211	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00349	5.46e-233	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase
BIGFKLDO_00350	1.79e-244	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Kinase, PfkB family
BIGFKLDO_00351	1.6e-215	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BIGFKLDO_00352	1.75e-186	-	1.1.1.69	-	IQ	ko:K00046	-	ko00000,ko01000	PFAM Short-chain dehydrogenase reductase SDR
BIGFKLDO_00353	5.64e-296	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00354	2.03e-294	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
BIGFKLDO_00355	9.35e-183	tig_1	-	-	O	ko:K03545	-	ko00000	peptidylprolyl isomerase
BIGFKLDO_00356	1.29e-280	-	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
BIGFKLDO_00357	2.33e-202	fumA	4.2.1.2	-	C	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type
BIGFKLDO_00358	5.19e-127	fumB	4.2.1.2	-	C	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Hydrolyase, tartrate beta subunit fumarate domain protein, Fe-S type
BIGFKLDO_00359	1.14e-83	-	-	-	K	-	-	-	iron dependent repressor
BIGFKLDO_00360	2.78e-273	-	-	-	T	-	-	-	diguanylate cyclase
BIGFKLDO_00361	0.0	-	2.7.11.1	-	KL	ko:K08282	-	ko00000,ko01000	SNF2 family
BIGFKLDO_00362	3.2e-241	-	3.4.13.19	-	E	ko:K01273	-	ko00000,ko00537,ko01000,ko01002,ko04147	Renal dipeptidase family protein
BIGFKLDO_00363	2.77e-174	yfcA	-	-	S	ko:K07090	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_00364	1.24e-200	-	-	-	S	-	-	-	EDD domain protein, DegV family
BIGFKLDO_00365	1.14e-83	-	-	-	S	ko:K07052	-	ko00000	Psort location CytoplasmicMembrane, score
BIGFKLDO_00366	7.6e-118	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
BIGFKLDO_00367	3.31e-150	fabG5	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
BIGFKLDO_00368	2.29e-308	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
BIGFKLDO_00369	1.25e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
BIGFKLDO_00370	2.34e-88	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
BIGFKLDO_00371	7.23e-51	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
BIGFKLDO_00372	3.53e-227	-	-	-	H	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BIGFKLDO_00374	9.27e-220	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
BIGFKLDO_00375	1.49e-97	-	-	-	K	-	-	-	Transcriptional regulator
BIGFKLDO_00376	1.49e-104	-	-	-	L	-	-	-	Nuclease-related domain
BIGFKLDO_00377	1.43e-44	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
BIGFKLDO_00378	6.21e-151	lrgB	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00379	8.54e-54	-	-	-	P	-	-	-	mercury ion transmembrane transporter activity
BIGFKLDO_00380	1.92e-204	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00381	0.0	malP_1	2.4.1.1	GT35	F	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
BIGFKLDO_00382	5.51e-158	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BIGFKLDO_00383	2.4e-33	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03425	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein secretion
BIGFKLDO_00384	8.62e-45	-	-	-	U	ko:K03117	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	mttA/Hcf106 family
BIGFKLDO_00385	0.0	-	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC-type multidrug transport system ATPase and permease
BIGFKLDO_00386	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
BIGFKLDO_00387	2.3e-251	-	-	-	S	-	-	-	Sel1-like repeats.
BIGFKLDO_00388	0.0	-	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
BIGFKLDO_00389	3.2e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF1653)
BIGFKLDO_00390	9.67e-229	-	-	-	-	-	-	-	-
BIGFKLDO_00391	5.15e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
BIGFKLDO_00392	2.61e-196	-	-	-	S	-	-	-	Cof-like hydrolase
BIGFKLDO_00393	2.02e-249	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00394	2.23e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
BIGFKLDO_00395	2.27e-219	tig	-	-	D	ko:K03545	-	ko00000	peptidyl-prolyl cis-trans isomerase activity
BIGFKLDO_00398	1.66e-232	-	-	-	S	-	-	-	Leucine rich repeats (6 copies)
BIGFKLDO_00399	0.0	-	-	-	S	-	-	-	VWA-like domain (DUF2201)
BIGFKLDO_00400	0.0	-	-	-	S	-	-	-	AAA domain (dynein-related subfamily)
BIGFKLDO_00401	1.6e-103	nifU	-	-	C	ko:K04488	-	ko00000	Fe-S iron-sulfur cluster assembly protein, NifU family
BIGFKLDO_00402	2.49e-297	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins
BIGFKLDO_00403	6.81e-111	-	-	-	-	-	-	-	-
BIGFKLDO_00404	3.71e-74	-	-	-	P	-	-	-	Psort location Cytoplasmic, score 8.96
BIGFKLDO_00405	1.34e-109	-	-	-	K	-	-	-	Transcriptional regulator
BIGFKLDO_00409	3.3e-302	adh	-	-	C	-	-	-	belongs to the iron- containing alcohol dehydrogenase family
BIGFKLDO_00410	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
BIGFKLDO_00411	1.63e-183	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BIGFKLDO_00412	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	TIGRFAM formate acetyltransferase
BIGFKLDO_00414	5.29e-239	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BIGFKLDO_00415	0.0	-	-	-	M	-	-	-	Glycosyl-transferase family 4
BIGFKLDO_00417	1.05e-274	-	-	-	G	-	-	-	Acyltransferase family
BIGFKLDO_00418	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Psort location Cytoplasmic, score
BIGFKLDO_00419	7.32e-46	-	-	-	IQ	ko:K02078	-	ko00000,ko00001	Acyl carrier protein
BIGFKLDO_00420	3.72e-283	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
BIGFKLDO_00421	4.97e-252	-	-	-	G	-	-	-	Transporter, major facilitator family protein
BIGFKLDO_00422	1.36e-151	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BIGFKLDO_00423	2.05e-38	ynzC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF896)
BIGFKLDO_00424	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BIGFKLDO_00425	1e-218	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
BIGFKLDO_00426	8.96e-252	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate-ammonia ligase
BIGFKLDO_00427	5.4e-162	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
BIGFKLDO_00428	4.52e-200	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type branched-chain amino acid transport systems ATPase component
BIGFKLDO_00429	1.43e-230	livM	-	-	E	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
BIGFKLDO_00430	3.12e-193	livH	-	-	E	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
BIGFKLDO_00431	4.43e-258	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type branched-chain amino acid transport systems periplasmic component
BIGFKLDO_00432	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00433	3.61e-304	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
BIGFKLDO_00435	6.07e-223	-	-	-	T	ko:K07814	-	ko00000,ko02022	Response regulator containing a CheY-like receiver domain and an HD-GYP domain
BIGFKLDO_00436	7.41e-203	-	-	-	T	ko:K07814	-	ko00000,ko02022	Response regulator containing a CheY-like receiver domain and an HD-GYP domain
BIGFKLDO_00437	1.37e-130	fliY1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
BIGFKLDO_00438	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
BIGFKLDO_00439	1.98e-166	spoVFA	-	-	EH	ko:K06410	-	ko00000	dipicolinic acid synthetase, A subunit
BIGFKLDO_00440	7.84e-133	spoVFB	-	-	H	ko:K06411	-	ko00000	Dipicolinic acid synthetase, B subunit
BIGFKLDO_00441	1.39e-311	dacB_3	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
BIGFKLDO_00442	5.62e-142	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
BIGFKLDO_00443	1.97e-186	pyrL	-	-	GM	ko:K01992,ko:K09690	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
BIGFKLDO_00444	5.44e-176	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
BIGFKLDO_00445	0.0	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase, group 2 family protein
BIGFKLDO_00446	1.91e-135	KatE	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00449	3.37e-311	rnfC	-	-	C	ko:K03615	-	ko00000	Part of a membrane complex involved in electron transport
BIGFKLDO_00450	1.47e-216	rnfD	-	-	C	ko:K03614	-	ko00000	Part of a membrane complex involved in electron transport
BIGFKLDO_00451	1.54e-119	rnfG	-	-	C	ko:K03612	-	ko00000	Part of a membrane complex involved in electron transport
BIGFKLDO_00452	1.23e-150	rnfE	-	-	C	ko:K03613	-	ko00000	Part of a membrane complex involved in electron transport
BIGFKLDO_00453	3.97e-137	rnfA	-	-	C	ko:K03617	-	ko00000	Part of a membrane complex involved in electron transport
BIGFKLDO_00454	6.23e-192	rnfB	-	-	C	ko:K03616	-	ko00000	electron transport complex, RnfABCDGE type, B subunit
BIGFKLDO_00455	1.1e-184	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
BIGFKLDO_00456	4.02e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
BIGFKLDO_00457	1.15e-120	-	-	-	-	-	-	-	-
BIGFKLDO_00458	7.08e-166	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00459	2.71e-198	-	-	-	S	-	-	-	Psort location
BIGFKLDO_00462	0.0	pz-A	-	-	E	-	-	-	Peptidase family M3
BIGFKLDO_00463	1.28e-102	-	-	-	S	-	-	-	Pfam:DUF3816
BIGFKLDO_00464	6.39e-298	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
BIGFKLDO_00465	6.61e-97	-	-	-	-	-	-	-	-
BIGFKLDO_00467	1.17e-220	-	-	-	GK	-	-	-	ROK family
BIGFKLDO_00468	1e-274	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BIGFKLDO_00469	2.41e-260	-	-	-	T	-	-	-	diguanylate cyclase
BIGFKLDO_00470	7.55e-48	-	-	-	-	-	-	-	-
BIGFKLDO_00471	1.39e-119	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
BIGFKLDO_00472	6.88e-231	scrK	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_00473	9.46e-298	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00474	8.82e-167	-	-	-	K	-	-	-	transcriptional regulator AraC family
BIGFKLDO_00476	9.12e-101	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
BIGFKLDO_00477	2.64e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF3846)
BIGFKLDO_00480	9.5e-204	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
BIGFKLDO_00481	4.89e-184	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
BIGFKLDO_00482	2.84e-205	-	-	-	S	-	-	-	Replication initiator protein A domain protein
BIGFKLDO_00484	3.83e-64	-	-	-	-	-	-	-	-
BIGFKLDO_00486	0.0	-	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_00487	4.69e-302	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
BIGFKLDO_00488	3.57e-260	pfkA	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
BIGFKLDO_00491	8.12e-158	-	-	-	S	-	-	-	HAD-hyrolase-like
BIGFKLDO_00492	7.7e-111	queT	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00493	1.37e-141	-	-	-	S	-	-	-	Flavin reductase-like protein
BIGFKLDO_00494	3.17e-235	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
BIGFKLDO_00495	3.64e-150	-	-	-	K	-	-	-	Cyclic nucleotide-monophosphate binding domain
BIGFKLDO_00496	2.7e-221	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	Menaquinone biosynthesis
BIGFKLDO_00497	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
BIGFKLDO_00498	6.26e-168	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	COG COG1349 Transcriptional regulators of sugar metabolism
BIGFKLDO_00499	8.43e-207	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
BIGFKLDO_00500	0.0	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system
BIGFKLDO_00501	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00502	0.0	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
BIGFKLDO_00503	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BIGFKLDO_00504	1.23e-181	fdhD	-	-	C	ko:K02379	-	ko00000	FdhD/NarQ family
BIGFKLDO_00506	4.48e-145	-	-	-	C	-	-	-	4Fe-4S binding domain
BIGFKLDO_00507	0.0	-	1.2.7.5	-	C	ko:K03738,ko:K19515	ko00030,ko00362,ko01100,ko01120,ko01200,map00030,map00362,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Aldehyde ferredoxin oxidoreductase, N-terminal domain
BIGFKLDO_00508	1.37e-198	-	-	-	-	-	-	-	-
BIGFKLDO_00509	3.33e-285	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA C-terminal region (domain IV)
BIGFKLDO_00510	6.06e-102	mobB	2.7.7.77	-	H	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Molybdopterin-guanine dinucleotide biosynthesis protein
BIGFKLDO_00511	1.81e-252	moeA2	-	-	H	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00512	4.94e-109	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
BIGFKLDO_00513	1.98e-233	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BIGFKLDO_00514	2.89e-223	mog	-	-	H	-	-	-	Molybdenum cofactor synthesis domain protein
BIGFKLDO_00515	2.19e-178	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, periplasmic molybdate-binding protein
BIGFKLDO_00516	4.29e-152	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Molybdate ABC transporter
BIGFKLDO_00517	4.06e-245	modC	3.6.3.29	-	E	ko:K02017	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
BIGFKLDO_00518	2.72e-82	-	-	-	S	-	-	-	protein with conserved CXXC pairs
BIGFKLDO_00519	5.47e-298	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00520	0.0	glpA	1.1.5.3	-	C	ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
BIGFKLDO_00521	1.86e-122	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Glycerol-3-phosphate responsive antiterminator
BIGFKLDO_00522	3.85e-301	-	-	-	E	-	-	-	Peptidase dimerisation domain
BIGFKLDO_00523	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
BIGFKLDO_00524	1.38e-189	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
BIGFKLDO_00525	7.38e-50	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BIGFKLDO_00526	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
BIGFKLDO_00527	2.27e-143	-	-	-	S	-	-	-	domain, Protein
BIGFKLDO_00528	1.56e-192	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
BIGFKLDO_00529	0.0	-	-	-	M	-	-	-	Gram-positive pilin backbone subunit 2, Cna-B-like domain
BIGFKLDO_00530	0.0	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BIGFKLDO_00531	3.6e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
BIGFKLDO_00532	4.76e-70	-	-	-	-	-	-	-	-
BIGFKLDO_00534	1.18e-46	-	-	-	S	-	-	-	Putative cell wall binding repeat
BIGFKLDO_00536	5.88e-164	-	-	-	K	ko:K22293	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
BIGFKLDO_00537	4.02e-196	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
BIGFKLDO_00538	8.64e-225	-	-	-	K	-	-	-	AraC-like ligand binding domain
BIGFKLDO_00540	1.56e-144	-	-	-	-	-	-	-	-
BIGFKLDO_00542	2.22e-185	-	-	-	S	-	-	-	TraX protein
BIGFKLDO_00543	0.0	hgdC2	-	-	I	-	-	-	CoA-substrate-specific enzyme activase
BIGFKLDO_00544	0.0	-	-	-	I	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00545	5.44e-225	-	-	-	O	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00546	0.0	tetP	-	-	J	-	-	-	elongation factor G
BIGFKLDO_00547	6.09e-199	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BIGFKLDO_00548	3.16e-178	-	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Nitroreductase family
BIGFKLDO_00549	5.48e-236	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BIGFKLDO_00550	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BIGFKLDO_00551	7.31e-38	-	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
BIGFKLDO_00552	2.64e-79	-	-	-	P	-	-	-	Belongs to the ArsC family
BIGFKLDO_00553	4.34e-189	-	-	-	-	-	-	-	-
BIGFKLDO_00554	2.56e-249	-	-	-	M	ko:K07011	-	ko00000	Glycosyltransferase like family 2
BIGFKLDO_00555	5.17e-123	-	-	-	S	-	-	-	Domain of unknown function (DUF4358)
BIGFKLDO_00556	1.32e-97	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator, AsnC family
BIGFKLDO_00557	1.3e-282	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BIGFKLDO_00558	3.22e-157	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
BIGFKLDO_00559	0.0	-	1.5.1.20, 2.1.1.10	-	H	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	homocysteine S-methyltransferase
BIGFKLDO_00560	7.27e-78	epsJ2	-	-	S	-	-	-	Psort location Cytoplasmic, score 9.97
BIGFKLDO_00561	0.0	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00562	1.04e-250	-	-	-	M	-	-	-	Glycosyltransferase like family 2
BIGFKLDO_00563	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
BIGFKLDO_00564	6.75e-66	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00565	7.33e-289	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydrofolate synthase activity
BIGFKLDO_00566	6.43e-66	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
BIGFKLDO_00567	9.26e-98	spoIIAB	2.7.11.1	-	T	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
BIGFKLDO_00568	3.81e-151	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Belongs to the sigma-70 factor family
BIGFKLDO_00569	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
BIGFKLDO_00570	2.02e-172	-	-	-	S	-	-	-	dinuclear metal center protein, YbgI
BIGFKLDO_00571	3.03e-135	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
BIGFKLDO_00572	4.95e-57	-	-	-	C	-	-	-	Hydrid cluster protein-associated redox disulfide domain
BIGFKLDO_00573	2.29e-195	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00574	3.27e-150	-	-	-	K	-	-	-	Belongs to the P(II) protein family
BIGFKLDO_00575	1.22e-300	-	-	-	T	-	-	-	Protein of unknown function (DUF1538)
BIGFKLDO_00576	0.0	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
BIGFKLDO_00577	1.14e-130	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
BIGFKLDO_00578	8.81e-211	-	-	-	EG	-	-	-	EamA-like transporter family
BIGFKLDO_00579	2.71e-122	-	-	-	-	-	-	-	-
BIGFKLDO_00580	9.11e-250	-	-	-	M	-	-	-	lipoprotein YddW precursor K01189
BIGFKLDO_00584	5.08e-210	-	-	-	S	-	-	-	Patatin-like phospholipase
BIGFKLDO_00585	0.0	-	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC-type multidrug transport system, ATPase and permease components
BIGFKLDO_00586	2.67e-163	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BIGFKLDO_00587	2.2e-129	-	-	-	S	-	-	-	Belongs to the UPF0340 family
BIGFKLDO_00588	8.15e-301	-	3.1.1.17	-	G	ko:K01053,ko:K02352	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	ko00000,ko00001,ko00002,ko01000,ko04147	gluconolactonase activity
BIGFKLDO_00589	0.0	-	2.3.1.79	-	M	ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide (six repeats)
BIGFKLDO_00590	3.29e-163	resD	-	-	K	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
BIGFKLDO_00591	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
BIGFKLDO_00593	3.87e-238	-	3.1.1.11	-	G	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Pectinesterase
BIGFKLDO_00594	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
BIGFKLDO_00595	1.06e-66	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
BIGFKLDO_00596	5.13e-64	-	-	-	-	-	-	-	-
BIGFKLDO_00597	0.0	gltX	6.1.1.17, 6.1.1.24	-	J	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BIGFKLDO_00598	8.89e-101	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00599	7.68e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
BIGFKLDO_00600	0.0	-	-	-	O	ko:K03697	-	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
BIGFKLDO_00601	4.89e-130	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_00602	2.49e-277	-	-	-	-	-	-	-	-
BIGFKLDO_00603	1.29e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
BIGFKLDO_00604	2.12e-185	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BIGFKLDO_00605	4.58e-217	cbiO	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BIGFKLDO_00606	1.02e-196	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BIGFKLDO_00607	5.86e-227	rlmL_1	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
BIGFKLDO_00608	3.64e-249	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
BIGFKLDO_00609	5.88e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
BIGFKLDO_00610	1.46e-117	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BIGFKLDO_00612	1.18e-103	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
BIGFKLDO_00613	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00614	1.3e-36	-	-	-	-	-	-	-	-
BIGFKLDO_00615	4.01e-91	-	-	-	S	ko:K06934	-	ko00000	Domain of unknown function (DUF296)
BIGFKLDO_00616	0.0	-	-	-	I	-	-	-	Lipase (class 3)
BIGFKLDO_00617	1.12e-212	-	-	-	K	-	-	-	LysR substrate binding domain protein
BIGFKLDO_00618	4.31e-178	-	-	-	S	-	-	-	TraX protein
BIGFKLDO_00621	1.52e-150	-	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	DNA-binding helix-turn-helix protein
BIGFKLDO_00622	0.0	-	-	-	L	-	-	-	DNA modification repair radical SAM protein
BIGFKLDO_00623	1.99e-194	-	-	-	L	-	-	-	DNA metabolism protein
BIGFKLDO_00624	2.25e-186	-	-	-	-	-	-	-	-
BIGFKLDO_00625	2.8e-57	spiA	-	-	K	ko:K18831	-	ko00000,ko02048,ko03000	sequence-specific DNA binding
BIGFKLDO_00626	3.27e-115	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BIGFKLDO_00627	0.0	-	-	-	S	ko:K07137	-	ko00000	Oxidoreductase
BIGFKLDO_00628	2.24e-148	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
BIGFKLDO_00629	3.06e-288	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00630	3.33e-140	-	-	-	F	-	-	-	Cytidylate kinase-like family
BIGFKLDO_00631	0.0	-	-	-	-	-	-	-	-
BIGFKLDO_00632	2.51e-197	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00633	1.49e-166	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
BIGFKLDO_00634	9.44e-183	-	-	-	-	-	-	-	-
BIGFKLDO_00636	1.65e-243	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
BIGFKLDO_00637	8.91e-248	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BIGFKLDO_00638	3.45e-264	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BIGFKLDO_00639	2.7e-295	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BIGFKLDO_00640	6.66e-113	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
BIGFKLDO_00641	1.65e-243	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	synthase
BIGFKLDO_00642	1.34e-297	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
BIGFKLDO_00643	6.99e-208	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
BIGFKLDO_00644	5.69e-234	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00645	0.0	-	-	-	O	-	-	-	ATPase, AAA family
BIGFKLDO_00646	5.31e-54	-	-	-	-	-	-	-	-
BIGFKLDO_00647	1.03e-237	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00648	4.82e-205	cobW	-	-	S	-	-	-	CobW/HypB/UreG, nucleotide-binding domain
BIGFKLDO_00649	0.0	pepQ	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
BIGFKLDO_00650	4.63e-123	rcoM2	-	-	KT	ko:K02477,ko:K21696	-	ko00000,ko02022,ko03000	phosphorelay signal transduction system
BIGFKLDO_00651	5.94e-238	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
BIGFKLDO_00652	9.87e-159	-	-	-	S	-	-	-	IA, variant 3
BIGFKLDO_00653	8.31e-274	-	-	-	S	ko:K07001	-	ko00000	Psort location Cytoplasmic, score 8.96
BIGFKLDO_00654	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BIGFKLDO_00655	6.62e-177	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
BIGFKLDO_00656	7.81e-209	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
BIGFKLDO_00657	6.49e-147	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
BIGFKLDO_00658	1.9e-170	-	-	-	K	ko:K05799	-	ko00000,ko03000	Transcriptional regulator, GntR family
BIGFKLDO_00659	0.0	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
BIGFKLDO_00660	1.71e-300	-	-	-	EG	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	ko00000,ko02000	Gluconate
BIGFKLDO_00661	3.26e-68	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
BIGFKLDO_00662	7.59e-124	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00663	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BIGFKLDO_00664	1.97e-136	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
BIGFKLDO_00665	2.24e-114	-	-	-	G	-	-	-	Ricin-type beta-trefoil
BIGFKLDO_00666	3.6e-316	-	-	-	V	-	-	-	MatE
BIGFKLDO_00668	1.01e-226	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	PBP superfamily domain
BIGFKLDO_00669	4.66e-117	-	-	-	S	-	-	-	Psort location
BIGFKLDO_00670	9.72e-147	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
BIGFKLDO_00671	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
BIGFKLDO_00672	0.0	-	-	-	C	-	-	-	FeS-containing Cyanobacterial-specific oxidoreductase
BIGFKLDO_00673	8.45e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
BIGFKLDO_00674	8.53e-120	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
BIGFKLDO_00675	5.13e-87	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00676	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
BIGFKLDO_00677	4.93e-286	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
BIGFKLDO_00679	9.64e-317	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	tRNA methylthiotransferase YqeV
BIGFKLDO_00680	0.0	-	-	-	C	-	-	-	4Fe-4S binding domain protein
BIGFKLDO_00683	5.26e-162	-	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Pyridoxal kinase
BIGFKLDO_00684	2.18e-127	trmL	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
BIGFKLDO_00685	7.03e-214	-	-	-	S	-	-	-	EDD domain protein, DegV family
BIGFKLDO_00686	2.71e-233	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BIGFKLDO_00687	1.96e-315	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine aminocarboxypropyltransferase cysteine synthase
BIGFKLDO_00688	4.1e-143	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type metal ion transport system permease component
BIGFKLDO_00689	1.72e-208	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BIGFKLDO_00690	9.14e-192	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
BIGFKLDO_00691	4.99e-180	-	-	-	S	-	-	-	Putative threonine/serine exporter
BIGFKLDO_00692	7.48e-92	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
BIGFKLDO_00694	1.94e-130	-	-	-	C	-	-	-	Nitroreductase family
BIGFKLDO_00695	7.47e-162	artP	-	-	ET	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
BIGFKLDO_00696	6.48e-167	ArtM	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	acid ABC transporter
BIGFKLDO_00697	1.73e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC-type polar amino acid transport system ATPase component
BIGFKLDO_00698	8.14e-265	leuB	1.1.1.85	-	C	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
BIGFKLDO_00699	7.69e-115	leuD	4.2.1.33, 4.2.1.35, 4.2.1.85	-	E	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BIGFKLDO_00700	1.94e-308	leuC	4.2.1.33, 4.2.1.35, 4.2.1.85	-	E	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BIGFKLDO_00701	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BIGFKLDO_00702	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BIGFKLDO_00704	6.31e-310	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine
BIGFKLDO_00705	3e-291	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Major Facilitator
BIGFKLDO_00706	2.72e-194	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00707	5.48e-206	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
BIGFKLDO_00708	1.87e-148	-	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	amino acid ABC transporter
BIGFKLDO_00709	5.62e-183	tcyN	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Amino acid ABC transporter ATP-binding protein, PAAT family
BIGFKLDO_00710	3.01e-187	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Amino acid ABC transporter substrate-binding protein, PAAT family (TC 3.A.1.3.-)
BIGFKLDO_00711	4.06e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
BIGFKLDO_00712	2.44e-186	-	-	-	U	-	-	-	Protein of unknown function (DUF1700)
BIGFKLDO_00713	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
BIGFKLDO_00714	4.88e-54	ptsH	-	-	G	ko:K11184,ko:K11189	-	ko00000,ko02000	phosphocarrier, HPr family
BIGFKLDO_00715	1e-316	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
BIGFKLDO_00716	9.81e-129	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BIGFKLDO_00717	4.87e-45	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
BIGFKLDO_00718	1.59e-49	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
BIGFKLDO_00719	4.48e-312	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BIGFKLDO_00720	2.82e-83	-	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BIGFKLDO_00721	6.49e-171	-	-	-	E	-	-	-	Pyridoxal-phosphate dependent protein
BIGFKLDO_00722	4.79e-307	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
BIGFKLDO_00723	2.42e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BIGFKLDO_00724	1.79e-105	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
BIGFKLDO_00725	1.43e-161	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Universal bacterial protein YeaZ
BIGFKLDO_00726	8.69e-96	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
BIGFKLDO_00727	8.76e-281	-	-	-	-	-	-	-	-
BIGFKLDO_00728	1.72e-278	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
BIGFKLDO_00729	1.31e-134	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
BIGFKLDO_00730	6.76e-170	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
BIGFKLDO_00731	7.25e-213	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
BIGFKLDO_00732	9.53e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
BIGFKLDO_00733	2.67e-192	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_00734	3.83e-231	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
BIGFKLDO_00735	0.0	-	-	-	G	-	-	-	ABC-type sugar transport system periplasmic component
BIGFKLDO_00736	2.53e-241	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	sugar-binding domain protein
BIGFKLDO_00737	0.0	-	2.4.1.20	GT36	G	ko:K00702	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyltransferase family 36
BIGFKLDO_00738	6.18e-115	thiW	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00739	4.27e-186	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BIGFKLDO_00740	6.92e-148	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
BIGFKLDO_00741	1.72e-315	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BIGFKLDO_00742	1.66e-280	-	-	-	E	ko:K03310	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_00743	0.0	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00744	1.07e-172	yacO	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BIGFKLDO_00745	9.93e-208	fba	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
BIGFKLDO_00746	7.2e-166	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
BIGFKLDO_00748	3.71e-35	-	-	-	S	-	-	-	InterPro IPR004919 IPR011089
BIGFKLDO_00749	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
BIGFKLDO_00750	1.34e-242	-	-	-	L	-	-	-	restriction endonuclease
BIGFKLDO_00751	4.49e-47	-	-	-	K	-	-	-	helix-turn-helix
BIGFKLDO_00752	2.44e-129	-	-	-	-	-	-	-	-
BIGFKLDO_00753	6.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
BIGFKLDO_00754	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
BIGFKLDO_00755	1.62e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BIGFKLDO_00756	1.86e-13	-	-	-	I	-	-	-	Acyltransferase
BIGFKLDO_00757	1.4e-234	-	-	-	I	-	-	-	Lipid kinase, YegS Rv2252 BmrU family
BIGFKLDO_00758	0.0	clpC	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Belongs to the ClpA ClpB family
BIGFKLDO_00759	1.23e-173	-	-	-	S	ko:K06872	-	ko00000	Pfam:TPM
BIGFKLDO_00760	4e-259	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
BIGFKLDO_00761	7.27e-281	-	-	-	S	-	-	-	SPFH domain-Band 7 family
BIGFKLDO_00762	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_00763	0.0	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	K transport systems, NAD-binding component
BIGFKLDO_00764	3.95e-309	pdp	2.4.2.2, 2.4.2.4	-	F	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
BIGFKLDO_00765	3.93e-292	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BIGFKLDO_00766	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
BIGFKLDO_00767	5.75e-103	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
BIGFKLDO_00768	1.7e-200	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
BIGFKLDO_00769	5.9e-233	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Psort location Cytoplasmic, score
BIGFKLDO_00771	3.55e-161	-	-	-	-	-	-	-	-
BIGFKLDO_00772	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BIGFKLDO_00773	6.08e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
BIGFKLDO_00774	0.0	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
BIGFKLDO_00775	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
BIGFKLDO_00776	1.51e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
BIGFKLDO_00777	2.11e-272	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
BIGFKLDO_00778	0.0	yybT	-	-	T	-	-	-	domain protein
BIGFKLDO_00779	0.0	rnj	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BIGFKLDO_00780	1.7e-115	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BIGFKLDO_00781	2.2e-117	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	sulfurtransferase activity
BIGFKLDO_00782	4.06e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
BIGFKLDO_00783	0.0	mrdA	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding protein, transpeptidase domain protein
BIGFKLDO_00784	6.63e-122	-	-	-	S	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
BIGFKLDO_00785	4.03e-162	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
BIGFKLDO_00786	1.63e-235	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein, MreB Mrl family
BIGFKLDO_00787	3.13e-133	maf	-	-	D	ko:K06287	-	ko00000	Maf-like protein
BIGFKLDO_00788	6.48e-99	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
BIGFKLDO_00789	0.0	ydcP	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
BIGFKLDO_00790	2.63e-69	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BIGFKLDO_00791	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
BIGFKLDO_00792	0.0	apu	2.4.1.25, 3.2.1.133, 3.2.1.135, 3.2.1.20, 3.2.1.54	GH13,GH31,GH77	G	ko:K00705,ko:K01187,ko:K01208	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
BIGFKLDO_00793	5.69e-100	-	-	-	OU	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00794	2.22e-156	qmcA	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
BIGFKLDO_00796	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
BIGFKLDO_00797	0.0	capD	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
BIGFKLDO_00798	1.37e-249	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	Stage V sporulation protein B
BIGFKLDO_00799	6.69e-201	mrp	-	-	D	-	-	-	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
BIGFKLDO_00800	0.0	gdhA	1.4.1.3, 1.4.1.4	-	C	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the Glu Leu Phe Val dehydrogenases family
BIGFKLDO_00801	0.0	hcp	1.7.99.1	-	C	ko:K05601	ko00910,map00910	ko00000,ko00001,ko01000	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O
BIGFKLDO_00803	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
BIGFKLDO_00804	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
BIGFKLDO_00805	0.0	-	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain protein
BIGFKLDO_00806	2.33e-300	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00807	7.49e-117	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
BIGFKLDO_00808	1.16e-75	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
BIGFKLDO_00809	1.01e-170	-	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
BIGFKLDO_00810	2.76e-181	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
BIGFKLDO_00811	0.0	-	-	-	T	-	-	-	Histidine kinase
BIGFKLDO_00812	3.7e-123	-	-	-	-	-	-	-	-
BIGFKLDO_00813	0.0	-	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase
BIGFKLDO_00814	1.64e-293	uxuA	4.2.1.8	-	H	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
BIGFKLDO_00816	0.0	dsdA	4.3.1.18	-	H	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
BIGFKLDO_00817	3.28e-52	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
BIGFKLDO_00818	4.33e-57	-	-	-	S	-	-	-	YoeB-like toxin of bacterial type II toxin-antitoxin system
BIGFKLDO_00819	1.01e-170	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
BIGFKLDO_00820	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family
BIGFKLDO_00822	4.57e-90	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BIGFKLDO_00823	1.27e-315	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BIGFKLDO_00824	8.65e-53	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
BIGFKLDO_00825	2.78e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
BIGFKLDO_00826	3.5e-249	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BIGFKLDO_00827	0.0	ymfH	-	-	S	-	-	-	Peptidase M16 inactive domain
BIGFKLDO_00828	4.26e-268	-	-	-	S	-	-	-	Peptidase M16 inactive domain protein
BIGFKLDO_00829	8.27e-184	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	serine-type D-Ala-D-Ala carboxypeptidase
BIGFKLDO_00830	1.24e-278	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
BIGFKLDO_00831	3.74e-210	thrB	2.7.1.39	-	H	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
BIGFKLDO_00832	3.14e-294	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
BIGFKLDO_00833	7.82e-87	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
BIGFKLDO_00834	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
BIGFKLDO_00836	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Na Pi-cotransporter II-like protein
BIGFKLDO_00838	1.28e-146	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
BIGFKLDO_00839	1.7e-217	-	-	-	P	ko:K03324	-	ko00000,ko02000	Na Pi-cotransporter
BIGFKLDO_00840	3.96e-72	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
BIGFKLDO_00841	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC-type multidrug transport system ATPase and permease
BIGFKLDO_00842	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC-type multidrug transport system ATPase and permease
BIGFKLDO_00843	1.43e-222	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_00844	0.0	-	-	-	C	-	-	-	domain protein
BIGFKLDO_00845	3.77e-217	-	-	-	S	-	-	-	ATPase family associated with various cellular activities (AAA)
BIGFKLDO_00846	0.0	-	-	-	P	-	-	-	von Willebrand factor (vWF) type A domain
BIGFKLDO_00848	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type oligopeptide transport system periplasmic component
BIGFKLDO_00849	2.35e-244	appF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
BIGFKLDO_00850	1.53e-241	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
BIGFKLDO_00851	3.06e-240	oppC	-	-	P	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BIGFKLDO_00852	4.68e-206	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BIGFKLDO_00853	1.48e-138	-	-	-	-	-	-	-	-
BIGFKLDO_00854	4.68e-183	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	capsular polysaccharide biosynthesis protein
BIGFKLDO_00855	4.04e-166	-	-	-	D	-	-	-	Capsular exopolysaccharide family
BIGFKLDO_00856	1.45e-145	-	-	-	M	-	-	-	Chain length determinant protein
BIGFKLDO_00857	7.42e-203	-	-	-	P	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
BIGFKLDO_00858	1.06e-258	-	-	-	P	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
BIGFKLDO_00859	0.0	-	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	transport systems ATPase components
BIGFKLDO_00860	4.81e-257	tmpC	-	-	S	ko:K07335	-	ko00000	basic membrane
BIGFKLDO_00861	5.31e-99	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
BIGFKLDO_00862	6.11e-169	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	purine-nucleoside phosphorylase
BIGFKLDO_00863	2.81e-303	-	-	-	D	-	-	-	G5
BIGFKLDO_00864	4.24e-217	rluD_2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
BIGFKLDO_00865	0.0	-	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
BIGFKLDO_00866	9.81e-77	-	-	-	S	-	-	-	NusG domain II
BIGFKLDO_00867	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BIGFKLDO_00869	6e-105	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00870	6.54e-157	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BIGFKLDO_00871	1.95e-173	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BIGFKLDO_00872	1.24e-47	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	sporulation transcriptional regulator SpoIIID
BIGFKLDO_00873	2.67e-131	-	-	-	S	ko:K16789	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
BIGFKLDO_00875	5.93e-304	nspC	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	carboxynorspermidine decarboxylase
BIGFKLDO_00876	9.23e-307	LYS1	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase
BIGFKLDO_00877	1.13e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
BIGFKLDO_00878	8.23e-215	speE	2.5.1.16	-	H	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BIGFKLDO_00879	0.0	speA	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Orn Lys Arg decarboxylase major
BIGFKLDO_00880	1.65e-173	-	-	-	T	-	-	-	response regulator
BIGFKLDO_00881	1.67e-209	-	-	-	T	-	-	-	GHKL domain
BIGFKLDO_00883	3.26e-106	-	-	-	G	-	-	-	Domain of unknown function (DUF386)
BIGFKLDO_00885	4.55e-128	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
BIGFKLDO_00887	3.02e-256	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_00888	1.41e-214	-	2.7.1.15, 2.7.1.83	-	H	ko:K00852,ko:K16328	ko00030,ko00240,map00030,map00240	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_00889	1.31e-218	-	2.7.1.40	-	H	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
BIGFKLDO_00890	1.5e-129	yfcE	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
BIGFKLDO_00891	6.38e-297	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00892	0.0	agcS_2	-	-	E	ko:K03310	-	ko00000	amino acid carrier protein
BIGFKLDO_00893	4.2e-268	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
BIGFKLDO_00894	5.61e-113	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
BIGFKLDO_00895	2.06e-259	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
BIGFKLDO_00896	3.45e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Psort location Cytoplasmic, score 8.96
BIGFKLDO_00897	5.95e-84	-	-	-	J	-	-	-	ribosomal protein
BIGFKLDO_00898	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BIGFKLDO_00899	1.81e-85	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BIGFKLDO_00900	5.45e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
BIGFKLDO_00901	1.91e-204	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BIGFKLDO_00902	2.13e-227	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
BIGFKLDO_00903	7.9e-288	pgk	2.7.2.3, 5.3.1.1	-	G	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
BIGFKLDO_00904	4.96e-172	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
BIGFKLDO_00905	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BIGFKLDO_00906	1.68e-254	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
BIGFKLDO_00907	1.56e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3783)
BIGFKLDO_00908	1.31e-244	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	synthase
BIGFKLDO_00909	3.25e-107	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BIGFKLDO_00910	3.31e-103	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BIGFKLDO_00911	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BIGFKLDO_00912	2.4e-257	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
BIGFKLDO_00913	4.02e-131	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BIGFKLDO_00914	8.08e-192	-	-	-	F	-	-	-	IMP cyclohydrolase-like protein
BIGFKLDO_00915	1.04e-292	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT IMPCHase bienzyme
BIGFKLDO_00916	0.0	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
BIGFKLDO_00917	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphoribosylformylglycinamidine synthase
BIGFKLDO_00918	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BIGFKLDO_00919	1.44e-164	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
BIGFKLDO_00920	7.73e-256	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Psort location Cytoplasmic, score
BIGFKLDO_00921	5.63e-177	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
BIGFKLDO_00922	1.51e-205	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
BIGFKLDO_00923	7.52e-179	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
BIGFKLDO_00925	9.32e-280	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
BIGFKLDO_00926	4.46e-193	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
BIGFKLDO_00927	2.72e-14	-	-	-	E	-	-	-	Parallel beta-helix repeats
BIGFKLDO_00928	4.69e-161	-	-	-	-	-	-	-	-
BIGFKLDO_00929	1.77e-238	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
BIGFKLDO_00930	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	citrate synthase
BIGFKLDO_00931	6.19e-101	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00932	8.17e-242	gap	1.2.1.12	-	C	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
BIGFKLDO_00933	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BIGFKLDO_00934	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BIGFKLDO_00935	7.18e-233	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00936	2.33e-198	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, TatD family
BIGFKLDO_00937	6.59e-52	-	-	-	-	-	-	-	-
BIGFKLDO_00938	7.49e-64	-	-	-	S	-	-	-	Stress responsive A/B Barrel Domain
BIGFKLDO_00942	3.04e-100	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00943	6.8e-151	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
BIGFKLDO_00944	2.19e-38	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BIGFKLDO_00945	2.61e-94	-	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BIGFKLDO_00946	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BIGFKLDO_00947	4.38e-209	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BIGFKLDO_00948	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BIGFKLDO_00949	4.73e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
BIGFKLDO_00950	9.36e-171	-	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score
BIGFKLDO_00951	1.56e-176	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
BIGFKLDO_00952	4.72e-212	bcrA_2	-	-	V	ko:K01990,ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
BIGFKLDO_00953	2.04e-167	-	-	-	K	-	-	-	response regulator receiver
BIGFKLDO_00954	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
BIGFKLDO_00955	6.73e-243	rluC	5.4.99.24	-	J	ko:K06179	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
BIGFKLDO_00956	9.04e-171	radC	-	-	L	ko:K03630	-	ko00000	Belongs to the UPF0758 family
BIGFKLDO_00957	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
BIGFKLDO_00958	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
BIGFKLDO_00959	4.49e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
BIGFKLDO_00960	8.93e-309	-	-	-	Q	-	-	-	Amidohydrolase family
BIGFKLDO_00961	0.0	comM	-	-	O	ko:K07391	-	ko00000	chelatase subunit ChlI
BIGFKLDO_00963	0.0	pgcA	5.4.2.2, 5.4.2.8	-	G	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
BIGFKLDO_00964	4.62e-273	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
BIGFKLDO_00965	1.11e-206	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BIGFKLDO_00966	9.56e-303	-	-	-	S	-	-	-	YbbR-like protein
BIGFKLDO_00967	0.0	-	-	-	S	ko:K07137	-	ko00000	FAD dependent oxidoreductase
BIGFKLDO_00968	1.01e-285	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BIGFKLDO_00969	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	exonuclease
BIGFKLDO_00970	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BIGFKLDO_00971	6.41e-106	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
BIGFKLDO_00972	2.64e-153	-	-	-	S	-	-	-	Metallo-beta-lactamase domain protein
BIGFKLDO_00973	0.0	hemZ	-	-	C	-	-	-	Coproporphyrinogen dehydrogenase
BIGFKLDO_00974	9.34e-225	-	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphoribulokinase uridine kinase family
BIGFKLDO_00975	7.52e-72	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
BIGFKLDO_00976	1.43e-121	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	MazG family
BIGFKLDO_00977	7.71e-52	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
BIGFKLDO_00978	6.72e-47	hslR	-	-	J	-	-	-	S4 domain protein
BIGFKLDO_00979	2.86e-09	yabP	-	-	S	-	-	-	Sporulation protein YabP
BIGFKLDO_00980	4.58e-92	-	-	-	-	-	-	-	-
BIGFKLDO_00981	4.49e-61	-	-	-	D	ko:K13052	-	ko00000,ko03036	septum formation initiator
BIGFKLDO_00982	1.11e-90	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	S1 RNA binding domain
BIGFKLDO_00983	1.73e-289	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
BIGFKLDO_00984	6.17e-203	-	-	-	-	-	-	-	-
BIGFKLDO_00985	1.17e-119	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_00986	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
BIGFKLDO_00987	0.0	-	-	-	N	-	-	-	Bacterial Ig-like domain 2
BIGFKLDO_00988	8.44e-244	-	-	-	M	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	HlyD family secretion protein
BIGFKLDO_00989	5.3e-104	-	-	-	KT	-	-	-	Transcriptional regulator
BIGFKLDO_00990	0.0	-	-	-	V	ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin transporter
BIGFKLDO_00992	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
BIGFKLDO_00993	0.0	-	-	-	J	ko:K07576	-	ko00000	Metallo-beta-lactamase domain protein
BIGFKLDO_00996	1.25e-85	-	-	-	S	-	-	-	Bacterial PH domain
BIGFKLDO_00997	0.0	-	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Beta-lactamase class C
BIGFKLDO_00998	2.78e-273	-	-	-	G	-	-	-	Major Facilitator
BIGFKLDO_00999	2e-242	-	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
BIGFKLDO_01000	9.13e-133	ribU	-	-	S	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BIGFKLDO_01001	0.0	-	-	-	V	-	-	-	MATE efflux family protein
BIGFKLDO_01002	8.26e-222	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Glycosyl transferase family 4
BIGFKLDO_01003	3.44e-203	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BIGFKLDO_01004	3.93e-133	fchA	-	-	E	-	-	-	Formiminotransferase-cyclodeaminase
BIGFKLDO_01005	1.93e-125	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BIGFKLDO_01006	1.78e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BIGFKLDO_01007	1.77e-114	btuR	2.5.1.17	-	H	ko:K19221	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cob(I)yrinic acid a,c-diamide adenosyltransferase
BIGFKLDO_01008	0.0	dinG	3.1.12.1, 3.6.4.12	-	L	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	HELICc2
BIGFKLDO_01009	1.28e-254	-	-	-	LO	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01010	4.09e-136	udgA	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
BIGFKLDO_01011	8.74e-236	pta	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	PFAM Phosphate acetyl butaryl transferase
BIGFKLDO_01012	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BIGFKLDO_01013	4.97e-70	-	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BIGFKLDO_01014	1.03e-138	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BIGFKLDO_01015	2.48e-111	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
BIGFKLDO_01017	3.82e-50	-	-	-	K	-	-	-	PFAM Phage derived protein Gp49-like (DUF891)
BIGFKLDO_01018	2.35e-52	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
BIGFKLDO_01019	1.75e-123	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
BIGFKLDO_01020	2.71e-145	-	-	-	S	-	-	-	EDD domain protein, DegV family
BIGFKLDO_01021	0.0	cls1	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BIGFKLDO_01022	5.97e-223	-	-	-	-	-	-	-	-
BIGFKLDO_01023	5.55e-167	fliY1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
BIGFKLDO_01024	8.74e-141	tcyB	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
BIGFKLDO_01025	2.13e-184	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
BIGFKLDO_01026	0.0	-	-	-	V	-	-	-	MATE efflux family protein
BIGFKLDO_01027	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	aconitate hydratase
BIGFKLDO_01028	1.42e-211	-	3.1.3.97	-	S	ko:K07053	-	ko00000,ko01000	PHP domain protein
BIGFKLDO_01029	7.47e-58	-	-	-	S	-	-	-	TSCPD domain
BIGFKLDO_01030	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
BIGFKLDO_01031	0.0	ushA	3.1.3.5, 3.6.1.45	-	F	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
BIGFKLDO_01034	1.4e-311	rhaA	5.3.1.14	-	G	ko:K01813	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
BIGFKLDO_01035	2.26e-207	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
BIGFKLDO_01036	3.91e-57	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
BIGFKLDO_01037	1.41e-22	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score 9.99
BIGFKLDO_01038	1.56e-88	-	-	-	K	-	-	-	AraC-like ligand binding domain
BIGFKLDO_01039	1.64e-233	-	-	-	S	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
BIGFKLDO_01040	6.89e-188	-	-	-	S	-	-	-	Cupin domain
BIGFKLDO_01041	1.62e-121	-	-	-	S	-	-	-	Flavin reductase
BIGFKLDO_01042	3.04e-105	-	-	-	K	-	-	-	Transcriptional regulator
BIGFKLDO_01043	3.09e-51	-	-	-	-	-	-	-	-
BIGFKLDO_01045	1.09e-249	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
BIGFKLDO_01046	1.36e-243	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
BIGFKLDO_01047	2.36e-268	-	-	-	S	-	-	-	domain protein
BIGFKLDO_01048	5.37e-220	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01049	0.0	-	-	-	T	-	-	-	Diguanylate cyclase (GGDEF) domain protein
BIGFKLDO_01050	1.57e-107	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01051	1.15e-115	niaR	-	-	S	ko:K07105	-	ko00000	3H domain
BIGFKLDO_01052	0.0	-	3.2.1.133, 3.2.1.135, 3.2.1.54, 3.5.4.33	GH13	G	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko03016	Alpha amylase, catalytic domain protein
BIGFKLDO_01053	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BIGFKLDO_01054	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_01055	1.7e-213	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
BIGFKLDO_01056	2.33e-284	-	-	-	C	-	-	-	4Fe-4S dicluster domain
BIGFKLDO_01057	0.0	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
BIGFKLDO_01058	6.02e-224	envE	3.1.4.46, 3.2.1.18, 3.2.1.8	GH33	E	ko:K01126,ko:K01181,ko:K01186	ko00511,ko00564,ko00600,ko04142,map00511,map00564,map00600,map04142	ko00000,ko00001,ko01000,ko02042	lipolytic protein G-D-S-L family
BIGFKLDO_01059	3.11e-44	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
BIGFKLDO_01060	1.43e-81	-	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
BIGFKLDO_01061	3.39e-17	-	-	-	-	-	-	-	-
BIGFKLDO_01062	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
BIGFKLDO_01063	2.13e-44	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	Fe2 transport system protein A
BIGFKLDO_01064	2.81e-36	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	Fe2 transport system protein A
BIGFKLDO_01065	1.42e-143	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01066	5.12e-139	-	-	-	F	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01067	1.31e-273	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
BIGFKLDO_01069	2.06e-234	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
BIGFKLDO_01070	6.52e-217	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BIGFKLDO_01071	7.79e-193	-	-	GT2,GT4	M	ko:K07011,ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 21
BIGFKLDO_01072	0.0	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase, group 2 family protein
BIGFKLDO_01073	7.87e-209	-	-	-	D	ko:K06381	-	ko00000	sporulation resulting in formation of a cellular spore
BIGFKLDO_01075	1.25e-146	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
BIGFKLDO_01076	1.81e-134	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
BIGFKLDO_01078	7.67e-95	-	-	-	K	-	-	-	DNA-templated transcription, initiation
BIGFKLDO_01081	2.87e-117	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
BIGFKLDO_01082	5.04e-94	-	-	-	-	-	-	-	-
BIGFKLDO_01085	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BIGFKLDO_01086	1.76e-178	cps4J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
BIGFKLDO_01087	4.74e-271	-	1.1.1.22	-	C	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
BIGFKLDO_01088	3.67e-254	lspL	5.1.3.6	-	M	ko:K08679	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	epimerase dehydratase
BIGFKLDO_01089	6.05e-293	wecB	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
BIGFKLDO_01090	1.32e-293	-	1.1.1.367	-	GM	ko:K19068	-	ko00000,ko01000	NAD dependent epimerase/dehydratase family
BIGFKLDO_01091	3.16e-70	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
BIGFKLDO_01092	8.85e-244	capD	5.1.3.2	-	M	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Polysaccharide biosynthesis protein
BIGFKLDO_01094	2.92e-105	-	-	-	S	-	-	-	Glycosyl transferase, family 2
BIGFKLDO_01095	1.11e-30	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
BIGFKLDO_01096	7.72e-96	-	-	-	M	-	-	-	Glycosyl transferases group 1
BIGFKLDO_01097	1.87e-20	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
BIGFKLDO_01098	1.46e-218	-	-	GT4	M	ko:K13004	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase 4-like
BIGFKLDO_01099	6.96e-157	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
BIGFKLDO_01100	4.75e-100	-	-	-	L	-	-	-	domain protein
BIGFKLDO_01101	1.42e-99	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4 family
BIGFKLDO_01102	7e-15	-	-	-	K	-	-	-	Helix-turn-helix domain
BIGFKLDO_01103	0.0	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
BIGFKLDO_01105	1.37e-157	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
BIGFKLDO_01106	1.01e-156	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
BIGFKLDO_01107	9.99e-305	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
BIGFKLDO_01108	2.87e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
BIGFKLDO_01109	1.09e-95	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
BIGFKLDO_01110	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
BIGFKLDO_01111	3.55e-260	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP-glucose 4-epimerase
BIGFKLDO_01112	1.26e-268	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
BIGFKLDO_01113	0.0	czcA	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BIGFKLDO_01114	5.64e-227	yaaT	-	-	S	-	-	-	PSP1 C-terminal domain protein
BIGFKLDO_01115	8.06e-17	-	-	-	C	-	-	-	4Fe-4S binding domain
BIGFKLDO_01116	3.26e-156	yfiC	2.1.1.223	-	S	ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
BIGFKLDO_01117	1.68e-192	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BIGFKLDO_01118	7.79e-80	yfcE1	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
BIGFKLDO_01119	4.33e-186	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	biotin acetyl-CoA-carboxylase ligase
BIGFKLDO_01120	2.5e-296	-	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
BIGFKLDO_01121	1.51e-72	PaaY	-	-	S	ko:K02617	-	ko00000	Bacterial transferase hexapeptide repeat protein
BIGFKLDO_01122	3.95e-206	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
BIGFKLDO_01123	1.28e-144	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01125	0.0	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
BIGFKLDO_01126	5.01e-80	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
BIGFKLDO_01127	5.71e-58	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
BIGFKLDO_01128	0.0	nifJ	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BIGFKLDO_01129	1.09e-128	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_01130	2.47e-134	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Pseudouridine synthase
BIGFKLDO_01131	1.82e-160	-	-	-	K	ko:K22293	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
BIGFKLDO_01132	2.43e-125	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
BIGFKLDO_01133	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BIGFKLDO_01134	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BIGFKLDO_01135	1.47e-54	-	-	-	S	-	-	-	Domain of unknown function (DUF370)
BIGFKLDO_01136	4.36e-260	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BIGFKLDO_01137	7.54e-44	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein
BIGFKLDO_01138	2.94e-169	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
BIGFKLDO_01139	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BIGFKLDO_01140	4.78e-22	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
BIGFKLDO_01141	4.55e-86	rnpA	3.1.26.5	-	J	ko:K03536,ko:K08998	-	ko00000,ko01000,ko03016	ribonuclease P activity
BIGFKLDO_01142	5.98e-64	yidD	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
BIGFKLDO_01143	8.26e-231	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
BIGFKLDO_01144	1.7e-203	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
BIGFKLDO_01145	4.69e-06	safA	-	-	V	-	-	-	Cysteine-rich secretory protein family
BIGFKLDO_01146	1.1e-310	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BIGFKLDO_01147	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
BIGFKLDO_01148	2.05e-165	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
BIGFKLDO_01149	1.13e-181	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
BIGFKLDO_01150	1.31e-183	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain
BIGFKLDO_01151	1.63e-199	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
BIGFKLDO_01152	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BIGFKLDO_01155	5.26e-156	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	phosphoglycolate phosphatase, bacterial
BIGFKLDO_01156	0.0	-	-	-	-	-	-	-	-
BIGFKLDO_01158	1.1e-158	-	-	-	C	ko:K03499	-	ko00000,ko02000	TrkA N-terminal domain protein
BIGFKLDO_01159	1.07e-94	trkA2	-	-	C	ko:K03499	-	ko00000,ko02000	TrkA N-terminal domain protein
BIGFKLDO_01160	5.92e-178	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
BIGFKLDO_01161	3.23e-262	clcA	-	-	P	ko:K03281	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_01162	7.95e-98	-	-	-	M	-	-	-	glycosyl transferase group 1
BIGFKLDO_01163	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BIGFKLDO_01164	1.13e-43	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
BIGFKLDO_01165	3.29e-93	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
BIGFKLDO_01166	1.54e-87	-	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
BIGFKLDO_01167	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BIGFKLDO_01168	1.13e-190	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BIGFKLDO_01169	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BIGFKLDO_01170	1.28e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BIGFKLDO_01171	1.75e-99	-	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BIGFKLDO_01172	2.72e-56	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BIGFKLDO_01173	1.63e-177	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
BIGFKLDO_01174	1.03e-111	-	-	-	-	-	-	-	-
BIGFKLDO_01175	2.35e-47	-	-	-	S	-	-	-	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
BIGFKLDO_01176	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
BIGFKLDO_01177	1.54e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
BIGFKLDO_01178	1.19e-259	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BIGFKLDO_01179	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BIGFKLDO_01180	9.21e-201	yabE	-	-	S	-	-	-	G5 domain
BIGFKLDO_01181	0.0	-	-	-	N	-	-	-	domain, Protein
BIGFKLDO_01182	3.29e-33	-	-	-	-	-	-	-	-
BIGFKLDO_01183	3.58e-243	-	-	-	N	-	-	-	Bacterial Ig-like domain (group 2)
BIGFKLDO_01185	4.35e-94	-	3.4.17.14	-	M	ko:K08640	-	ko00000,ko01000,ko01002,ko01011	Peptidase M15A
BIGFKLDO_01186	1.29e-31	-	-	-	-	-	-	-	-
BIGFKLDO_01187	6.31e-51	-	-	-	S	-	-	-	SPP1 phage holin
BIGFKLDO_01188	2.06e-129	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01189	1.3e-239	-	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase NAD-binding domain protein
BIGFKLDO_01190	2.26e-213	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BIGFKLDO_01191	1.63e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BIGFKLDO_01192	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
BIGFKLDO_01193	0.0	-	-	-	S	ko:K01421	-	ko00000	Psort location Cellwall, score
BIGFKLDO_01194	0.0	-	-	-	S	ko:K07003	-	ko00000	Psort location CytoplasmicMembrane, score
BIGFKLDO_01195	1.25e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
BIGFKLDO_01197	8.74e-62	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
BIGFKLDO_01198	1.9e-26	-	-	-	D	-	-	-	Plasmid stabilization system
BIGFKLDO_01199	0.0	glpK	2.7.1.30	-	H	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BIGFKLDO_01200	0.0	-	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
BIGFKLDO_01201	6.09e-275	-	-	-	S	-	-	-	Belongs to the UPF0348 family
BIGFKLDO_01202	7.34e-291	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BIGFKLDO_01203	1.42e-70	-	-	-	K	-	-	-	Probable zinc-ribbon domain
BIGFKLDO_01204	4.09e-249	-	-	GT2	M	ko:K19427	-	ko00000,ko01000	Glycosyltransferase group 2 family protein
BIGFKLDO_01205	0.0	-	-	-	S	-	-	-	O-Antigen ligase
BIGFKLDO_01206	1.28e-92	-	-	-	M	-	-	-	Glycosyltransferase Family 4
BIGFKLDO_01207	2.58e-296	-	-	-	V	-	-	-	Glycosyl transferase, family 2
BIGFKLDO_01208	0.0	-	-	-	M	-	-	-	Diguanylate cyclase, GGDEF domain
BIGFKLDO_01209	1.16e-302	-	-	-	-	-	-	-	-
BIGFKLDO_01210	7.19e-235	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
BIGFKLDO_01211	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
BIGFKLDO_01212	9.33e-295	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BIGFKLDO_01213	4.61e-188	ttcA2	-	-	H	-	-	-	Belongs to the TtcA family
BIGFKLDO_01215	2.91e-99	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BIGFKLDO_01216	1.54e-87	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
BIGFKLDO_01217	1.6e-216	-	-	-	S	-	-	-	CAAX protease self-immunity
BIGFKLDO_01218	3.13e-62	-	-	-	S	-	-	-	Putative heavy-metal-binding
BIGFKLDO_01219	6.3e-142	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
BIGFKLDO_01220	1.59e-288	cshA	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	Belongs to the DEAD box helicase family
BIGFKLDO_01221	5.07e-62	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	bacterial (prokaryotic) histone like domain
BIGFKLDO_01222	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BIGFKLDO_01223	1.37e-273	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
BIGFKLDO_01224	3.09e-139	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BIGFKLDO_01225	4.4e-217	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
BIGFKLDO_01226	1.64e-191	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
BIGFKLDO_01227	1.25e-206	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
BIGFKLDO_01228	5.84e-296	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
BIGFKLDO_01230	1.76e-160	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine O-acetyltransferase
BIGFKLDO_01231	0.0	-	-	-	T	ko:K07814	-	ko00000,ko02022	HD domain
BIGFKLDO_01233	3.23e-254	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BIGFKLDO_01234	4.84e-312	murA2	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
BIGFKLDO_01235	3.44e-233	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
BIGFKLDO_01236	0.0	spoVD	3.4.16.4	-	M	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein
BIGFKLDO_01237	4.05e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
BIGFKLDO_01238	4.05e-208	-	-	-	S	-	-	-	Phospholipase, patatin family
BIGFKLDO_01239	4.31e-63	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
BIGFKLDO_01240	5.93e-113	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BIGFKLDO_01241	1.68e-157	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
BIGFKLDO_01242	2.8e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BIGFKLDO_01243	8.66e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
BIGFKLDO_01244	4.49e-46	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
BIGFKLDO_01245	1.26e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
BIGFKLDO_01246	5.34e-269	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
BIGFKLDO_01247	9.85e-197	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
BIGFKLDO_01248	6.53e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
BIGFKLDO_01249	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
BIGFKLDO_01250	2.76e-247	dus	-	-	H	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BIGFKLDO_01251	1.47e-136	yfbR	3.1.3.89	-	S	ko:K07023,ko:K08722	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	PFAM metal-dependent phosphohydrolase HD sub domain
BIGFKLDO_01252	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01253	2.35e-232	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
BIGFKLDO_01254	1.81e-203	-	-	-	P	ko:K05832	-	ko00000,ko00002,ko02000	Branched-chain amino acid ABC transporter, permease protein
BIGFKLDO_01255	3.12e-183	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
BIGFKLDO_01256	1.56e-152	-	-	-	K	-	-	-	FCD
BIGFKLDO_01257	1.05e-117	-	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
BIGFKLDO_01258	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	asparagine synthase (glutamine-hydrolyzing)
BIGFKLDO_01259	0.0	fusA2	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	translation elongation
BIGFKLDO_01261	2.58e-117	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
BIGFKLDO_01262	6.74e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BIGFKLDO_01263	3.61e-125	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
BIGFKLDO_01266	1.27e-115	-	-	-	K	ko:K03088	-	ko00000,ko03021	Putative ATPase subunit of terminase (gpP-like)
BIGFKLDO_01267	8.43e-225	-	-	-	M	-	-	-	Domain of unknown function (DUF4349)
BIGFKLDO_01268	2.83e-201	-	-	-	IQ	-	-	-	short chain dehydrogenase
BIGFKLDO_01270	2.7e-36	-	-	-	K	-	-	-	Transcriptional regulator
BIGFKLDO_01271	5.74e-21	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
BIGFKLDO_01272	9.39e-69	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01273	4.78e-163	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	PFAM Bacterial regulatory proteins, gntR family
BIGFKLDO_01274	2.05e-79	-	2.7.1.191	-	G	ko:K02793,ko:K19506	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
BIGFKLDO_01275	1.51e-105	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
BIGFKLDO_01276	1.71e-174	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
BIGFKLDO_01277	1.61e-188	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
BIGFKLDO_01278	1.9e-232	-	-	-	M	-	-	-	SIS domain
BIGFKLDO_01279	8.11e-145	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
BIGFKLDO_01280	3.89e-210	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
BIGFKLDO_01281	3.99e-53	-	-	-	-	-	-	-	-
BIGFKLDO_01282	1.88e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
BIGFKLDO_01283	0.0	mtlA	2.7.1.197	-	G	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system
BIGFKLDO_01284	0.0	-	-	-	H	ko:K03483	-	ko00000,ko03000	PRD domain
BIGFKLDO_01285	8.02e-226	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
BIGFKLDO_01286	4.44e-173	-	-	-	K	ko:K02081	-	ko00000,ko03000	DeoR C terminal sensor domain
BIGFKLDO_01287	9.07e-177	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
BIGFKLDO_01288	4.62e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
BIGFKLDO_01289	2.16e-197	-	-	-	U	-	-	-	domain, Protein
BIGFKLDO_01290	9.01e-165	-	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
BIGFKLDO_01291	3.44e-300	-	-	-	T	-	-	-	GHKL domain
BIGFKLDO_01292	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
BIGFKLDO_01293	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 3 family
BIGFKLDO_01294	4.29e-135	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01295	5.68e-287	rny	-	-	D	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
BIGFKLDO_01297	3.61e-270	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BIGFKLDO_01298	8.89e-100	-	-	-	-	-	-	-	-
BIGFKLDO_01299	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BIGFKLDO_01300	0.0	-	-	-	P	ko:K03320	-	ko00000,ko02000	Belongs to the P(II) protein family
BIGFKLDO_01301	8.75e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1622)
BIGFKLDO_01302	8.12e-151	-	-	-	G	-	-	-	Ribose Galactose Isomerase
BIGFKLDO_01303	7.52e-84	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
BIGFKLDO_01304	1.62e-188	-	1.1.1.69	-	IQ	ko:K00046	-	ko00000,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_01305	2.58e-179	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
BIGFKLDO_01306	3.7e-259	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
BIGFKLDO_01311	8.01e-171	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate binding protein
BIGFKLDO_01312	2.1e-197	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
BIGFKLDO_01313	6.09e-176	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate ABC transporter
BIGFKLDO_01314	6.61e-181	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
BIGFKLDO_01315	2.57e-148	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
BIGFKLDO_01316	1.17e-82	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
BIGFKLDO_01317	7.26e-115	-	-	-	J	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01318	6.87e-229	-	-	-	JM	-	-	-	Nucleotidyl transferase
BIGFKLDO_01319	7.62e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01320	3.21e-193	ytrP	2.7.7.65	-	T	ko:K13069	-	ko00000,ko01000	diguanylate cyclase activity
BIGFKLDO_01321	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_01325	3.46e-205	nfnA	1.18.1.2, 1.19.1.1	-	C	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	ko00000,ko00001,ko01000	domain protein
BIGFKLDO_01326	0.0	gltA	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
BIGFKLDO_01327	1.92e-106	-	-	-	S	-	-	-	CBS domain
BIGFKLDO_01328	4.34e-75	-	-	-	S	-	-	-	Asp23 family, cell envelope-related function
BIGFKLDO_01329	0.0	-	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
BIGFKLDO_01330	0.0	polC	2.7.7.7	-	L	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BIGFKLDO_01331	1.49e-251	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BIGFKLDO_01332	1.56e-255	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Metalloprotease
BIGFKLDO_01333	5.41e-274	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
BIGFKLDO_01334	1.44e-195	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_01335	4e-173	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BIGFKLDO_01336	1.04e-117	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
BIGFKLDO_01337	6.61e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
BIGFKLDO_01338	1.18e-166	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01339	4.23e-54	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
BIGFKLDO_01342	1.68e-177	spo0A	-	-	K	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
BIGFKLDO_01343	8.22e-288	spoIVB	3.4.21.116	-	S	ko:K06399	-	ko00000,ko01000,ko01002	stage IV sporulation protein B
BIGFKLDO_01344	1.84e-260	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BIGFKLDO_01345	1.85e-240	-	-	-	S	-	-	-	Prokaryotic RING finger family 1
BIGFKLDO_01346	2.97e-211	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
BIGFKLDO_01347	5.38e-272	napA	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_01348	4.49e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
BIGFKLDO_01349	8.93e-100	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
BIGFKLDO_01350	8.86e-56	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BIGFKLDO_01351	3.91e-142	-	-	-	F	-	-	-	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BIGFKLDO_01352	8.7e-233	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
BIGFKLDO_01353	4.12e-310	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
BIGFKLDO_01354	2.31e-195	-	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
BIGFKLDO_01355	4.49e-196	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_01356	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_01359	2.38e-310	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family
BIGFKLDO_01360	3.63e-214	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01361	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BIGFKLDO_01362	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Melibiase
BIGFKLDO_01363	8.03e-311	lacS	-	-	G	ko:K03292,ko:K11104,ko:K16209	-	ko00000,ko02000	MFS/sugar transport protein
BIGFKLDO_01364	0.0	lacZ	3.2.1.23, 3.2.1.31	-	G	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
BIGFKLDO_01365	1.48e-123	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
BIGFKLDO_01366	3.43e-17	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
BIGFKLDO_01367	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
BIGFKLDO_01368	3.16e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
BIGFKLDO_01369	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding protein, transpeptidase domain protein
BIGFKLDO_01370	2.43e-108	-	-	-	S	ko:K02441	-	ko00000	Rhomboid family
BIGFKLDO_01371	3.12e-115	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01372	4.15e-298	rlmI	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
BIGFKLDO_01373	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
BIGFKLDO_01374	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
BIGFKLDO_01375	1.93e-126	-	-	-	K	ko:K22010	-	ko00000,ko00002,ko02022	ANTAR domain protein
BIGFKLDO_01376	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
BIGFKLDO_01377	0.0	-	-	-	T	-	-	-	diguanylate cyclase
BIGFKLDO_01380	5.34e-185	-	-	-	G	-	-	-	polysaccharide deacetylase
BIGFKLDO_01381	9e-192	hmrR	-	-	K	-	-	-	Transcriptional regulator
BIGFKLDO_01382	0.0	apeA	-	-	E	-	-	-	M18 family aminopeptidase
BIGFKLDO_01383	1.23e-95	-	-	GH23	M	ko:K08309	-	ko00000,ko01000,ko01011	Transglycosylase SLT domain
BIGFKLDO_01384	1.68e-131	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BIGFKLDO_01385	5.35e-246	sua	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
BIGFKLDO_01386	3.52e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BIGFKLDO_01387	1.92e-38	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01388	2.11e-223	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	S1 RNA binding domain protein
BIGFKLDO_01389	2.29e-125	-	-	-	K	-	-	-	Domain of unknown function (DUF4364)
BIGFKLDO_01390	1.32e-311	spoIVA	-	-	P	ko:K06398	-	ko00000	Stage IV sporulation protein A (spore_IV_A)
BIGFKLDO_01391	0.0	aspS	6.1.1.12, 6.1.1.23	-	J	ko:K01876,ko:K09759	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
BIGFKLDO_01392	3.08e-146	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
BIGFKLDO_01393	1.34e-298	-	-	-	V	-	-	-	MATE efflux family protein
BIGFKLDO_01394	9.04e-99	-	-	-	P	ko:K07238	-	ko00000,ko02000	Metal cation transporter, ZIP family
BIGFKLDO_01397	6.11e-118	yvdD	3.2.2.10	-	L	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
BIGFKLDO_01398	2.95e-120	chrA2	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
BIGFKLDO_01399	1.92e-120	chrA1	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
BIGFKLDO_01400	2.15e-181	-	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
BIGFKLDO_01401	7.76e-299	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
BIGFKLDO_01402	2.19e-188	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_01403	3.93e-181	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component I
BIGFKLDO_01404	8.61e-251	potA	3.6.3.31	-	P	ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
BIGFKLDO_01405	1.06e-211	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
BIGFKLDO_01406	0.0	-	-	-	N	ko:K01992	-	ko00000,ko00002,ko02000	transport system
BIGFKLDO_01407	2.35e-187	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
BIGFKLDO_01408	4.42e-174	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
BIGFKLDO_01409	2.24e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
BIGFKLDO_01411	8.25e-47	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
BIGFKLDO_01413	1.32e-17	-	-	-	-	-	-	-	-
BIGFKLDO_01416	5.27e-104	-	-	-	L	-	-	-	Transposase IS116/IS110/IS902 family
BIGFKLDO_01417	8.63e-154	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BIGFKLDO_01418	3.78e-271	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
BIGFKLDO_01422	9.8e-167	-	-	-	T	-	-	-	response regulator receiver
BIGFKLDO_01423	0.0	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
BIGFKLDO_01424	8.39e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
BIGFKLDO_01425	2.96e-242	-	-	-	C	ko:K03614	-	ko00000	Belongs to the NqrB RnfD family
BIGFKLDO_01426	2.56e-162	-	-	-	C	ko:K03613	-	ko00000	Psort location CytoplasmicMembrane, score
BIGFKLDO_01427	2.59e-102	-	-	-	C	ko:K03617	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_01428	3.15e-226	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
BIGFKLDO_01429	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
BIGFKLDO_01430	0.0	rhlE	3.6.4.13	-	L	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Belongs to the DEAD box helicase family
BIGFKLDO_01431	2.01e-209	rlmA	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase
BIGFKLDO_01432	4.79e-294	-	-	-	I	-	-	-	Psort location Cytoplasmic, score 7.50
BIGFKLDO_01433	1.38e-315	-	-	-	V	-	-	-	MATE efflux family protein
BIGFKLDO_01434	0.0	-	-	-	E	ko:K03310	-	ko00000	amino acid carrier protein
BIGFKLDO_01436	1.37e-115	-	-	-	-	-	-	-	-
BIGFKLDO_01437	0.0	-	-	-	K	ko:K00375	-	ko00000,ko03000	Transcriptional regulator, GntR family
BIGFKLDO_01438	5.13e-141	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01439	4.04e-255	-	-	-	S	ko:K07007	-	ko00000	Flavoprotein family
BIGFKLDO_01440	1.33e-118	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein T
BIGFKLDO_01442	1.37e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
BIGFKLDO_01443	3.18e-118	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BIGFKLDO_01444	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
BIGFKLDO_01445	2.79e-275	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
BIGFKLDO_01448	9.9e-285	-	-	-	S	-	-	-	SGNH hydrolase-like domain, acetyltransferase AlgX
BIGFKLDO_01449	0.0	-	-	-	M	ko:K19294	-	ko00000	Psort location CytoplasmicMembrane, score
BIGFKLDO_01450	6.97e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4358)
BIGFKLDO_01451	5.53e-177	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Serine-type D-Ala-D-Ala carboxypeptidase
BIGFKLDO_01452	8.17e-98	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
BIGFKLDO_01453	9.02e-232	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
BIGFKLDO_01454	4.84e-73	spoVAE	-	-	S	ko:K06407	-	ko00000	Stage V sporulation protein AE
BIGFKLDO_01456	1.86e-44	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
BIGFKLDO_01457	2.77e-176	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BIGFKLDO_01458	5.29e-245	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
BIGFKLDO_01459	9.12e-119	-	-	-	-	-	-	-	-
BIGFKLDO_01461	4.93e-40	-	-	-	-	-	-	-	-
BIGFKLDO_01463	1.03e-178	-	-	-	K	-	-	-	Peptidase S24-like
BIGFKLDO_01465	1.75e-166	-	-	-	E	-	-	-	IrrE N-terminal-like domain
BIGFKLDO_01466	3.41e-172	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
BIGFKLDO_01467	1.33e-183	-	-	-	K	-	-	-	Toxic component of a toxin-antitoxin (TA) module
BIGFKLDO_01468	8.72e-208	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01469	0.0	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
BIGFKLDO_01470	8.76e-93	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
BIGFKLDO_01473	1.88e-307	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
BIGFKLDO_01474	4.49e-282	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BIGFKLDO_01475	7.68e-274	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	aminotransferase class V
BIGFKLDO_01476	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
BIGFKLDO_01477	2.45e-214	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
BIGFKLDO_01478	3.13e-65	-	-	-	-	-	-	-	-
BIGFKLDO_01479	3.08e-74	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01480	1.81e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BIGFKLDO_01481	8.16e-185	Nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV
BIGFKLDO_01482	2.75e-116	yqeG	-	-	S	ko:K07015	-	ko00000	Mitochondrial PGP phosphatase
BIGFKLDO_01483	5.46e-27	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
BIGFKLDO_01484	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
BIGFKLDO_01485	1.39e-83	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
BIGFKLDO_01486	1.26e-281	-	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
BIGFKLDO_01487	1.08e-132	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	HD superfamily hydrolase involved in NAD metabolism
BIGFKLDO_01488	7.75e-145	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BIGFKLDO_01489	8.86e-62	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein, YhbY family
BIGFKLDO_01490	4.89e-152	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BIGFKLDO_01491	4.93e-216	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BIGFKLDO_01492	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
BIGFKLDO_01493	8.34e-155	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
BIGFKLDO_01494	8.79e-239	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
BIGFKLDO_01495	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BIGFKLDO_01496	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BIGFKLDO_01497	2.09e-215	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
BIGFKLDO_01498	2.39e-181	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BIGFKLDO_01499	8.15e-47	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BIGFKLDO_01500	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01501	0.0	-	-	-	-	-	-	-	-
BIGFKLDO_01502	1.29e-101	-	-	-	KT	-	-	-	Response regulator of the LytR AlgR family
BIGFKLDO_01503	7.6e-159	-	-	-	KT	-	-	-	LytTr DNA-binding domain
BIGFKLDO_01504	4.15e-303	-	-	-	T	-	-	-	GHKL domain
BIGFKLDO_01505	1.46e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
BIGFKLDO_01506	5.62e-55	-	-	-	S	-	-	-	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121
BIGFKLDO_01507	0.0	copA_1	-	-	P	ko:K12950	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
BIGFKLDO_01508	4.75e-214	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_01509	1.09e-93	-	-	-	S	-	-	-	FMN_bind
BIGFKLDO_01510	1.38e-214	-	-	-	C	-	-	-	FMN-binding domain protein
BIGFKLDO_01511	1.86e-302	-	-	-	S	-	-	-	Penicillin-binding protein Tp47 domain a
BIGFKLDO_01512	0.0	-	-	-	V	-	-	-	MATE efflux family protein
BIGFKLDO_01513	7.51e-189	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
BIGFKLDO_01514	4.26e-108	-	-	-	S	-	-	-	small multi-drug export protein
BIGFKLDO_01515	0.0	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_01516	4.49e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF3842)
BIGFKLDO_01517	4.41e-133	-	-	-	S	-	-	-	metal-dependent phosphohydrolase, HD sub domain
BIGFKLDO_01518	2.29e-48	-	-	-	S	-	-	-	Transcriptional Coactivator p15 (PC4)
BIGFKLDO_01520	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	exonuclease SbcC
BIGFKLDO_01521	1.45e-226	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
BIGFKLDO_01522	1.76e-109	-	-	-	M	-	-	-	Putative peptidoglycan binding domain
BIGFKLDO_01523	1.1e-139	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
BIGFKLDO_01524	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
BIGFKLDO_01525	4.12e-56	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
BIGFKLDO_01526	2.04e-105	Lrp	-	-	K	-	-	-	Transcriptional regulator, AsnC family
BIGFKLDO_01527	7.61e-291	aspC	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
BIGFKLDO_01528	3.55e-200	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BIGFKLDO_01529	1.58e-30	-	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
BIGFKLDO_01530	2.08e-159	-	-	-	-	-	-	-	-
BIGFKLDO_01531	3.5e-64	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
BIGFKLDO_01532	1.28e-166	-	5.2.1.8	-	M	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BIGFKLDO_01533	8.64e-97	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BIGFKLDO_01534	0.0	addB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
BIGFKLDO_01535	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
BIGFKLDO_01536	1.65e-127	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BIGFKLDO_01537	0.0	-	-	-	U	-	-	-	Psort location Cytoplasmic, score 8.96
BIGFKLDO_01538	3.51e-194	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
BIGFKLDO_01539	2.05e-51	-	-	-	-	-	-	-	-
BIGFKLDO_01541	6.45e-70	-	-	-	T	-	-	-	Hpt domain
BIGFKLDO_01542	2.92e-233	-	1.1.1.79, 1.1.1.81	-	EH	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
BIGFKLDO_01543	7.35e-71	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
BIGFKLDO_01544	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glutaminyl-tRNA synthetase
BIGFKLDO_01545	4.7e-205	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01546	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
BIGFKLDO_01547	0.0	-	1.1.1.17, 1.1.1.58	-	C	ko:K00009,ko:K00041	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase
BIGFKLDO_01548	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	SAF domain protein
BIGFKLDO_01550	1.33e-224	-	-	-	G	-	-	-	Aldose 1-epimerase
BIGFKLDO_01551	3.31e-84	-	-	-	L	-	-	-	Dinitrogenase iron-molybdenum cofactor
BIGFKLDO_01552	4.65e-185	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01553	2.16e-210	-	-	-	K	-	-	-	LysR substrate binding domain protein
BIGFKLDO_01554	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BIGFKLDO_01555	1.96e-206	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
BIGFKLDO_01557	6.82e-223	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
BIGFKLDO_01558	3.68e-312	cca	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	tRNA nucleotidyltransferase poly(A) polymerase
BIGFKLDO_01559	1.73e-271	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
BIGFKLDO_01560	6.64e-186	thiF	-	-	H	ko:K22132	-	ko00000,ko03016	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
BIGFKLDO_01561	1.2e-203	-	-	-	S	ko:K07089	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_01562	1.8e-220	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
BIGFKLDO_01563	7.66e-116	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	UreE urease accessory protein, C-terminal domain
BIGFKLDO_01564	1.56e-138	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
BIGFKLDO_01565	2.03e-253	-	-	-	P	-	-	-	Belongs to the TelA family
BIGFKLDO_01566	6.21e-164	-	-	-	-	-	-	-	-
BIGFKLDO_01567	1.04e-82	-	-	-	S	ko:K06872	-	ko00000	Pfam:TPM
BIGFKLDO_01568	1.35e-283	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BIGFKLDO_01569	8.49e-79	-	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
BIGFKLDO_01570	3.34e-286	-	-	-	S	ko:K06923	-	ko00000	ATPase (AAA superfamily)
BIGFKLDO_01571	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	acetolactate synthase large subunit
BIGFKLDO_01572	1.48e-123	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetolactate synthase small
BIGFKLDO_01573	1.31e-245	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BIGFKLDO_01574	0.0	ilvD	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
BIGFKLDO_01575	2.93e-159	cpsE	-	-	M	-	-	-	sugar transferase
BIGFKLDO_01577	2.39e-85	-	3.1.2.29	-	S	ko:K18700	-	ko00000,ko01000	thioesterase
BIGFKLDO_01579	0.0	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01580	2.16e-103	-	-	-	K	-	-	-	Winged helix DNA-binding domain
BIGFKLDO_01581	1.84e-86	-	-	-	S	ko:K08978	-	ko00000,ko02000	EamA-like transporter family
BIGFKLDO_01582	0.0	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
BIGFKLDO_01583	2.06e-297	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BIGFKLDO_01584	2.11e-249	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BIGFKLDO_01585	6.5e-146	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
BIGFKLDO_01586	1.41e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BIGFKLDO_01587	1.18e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BIGFKLDO_01588	3.99e-180	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
BIGFKLDO_01589	1.57e-148	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BIGFKLDO_01590	1.58e-202	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_01591	4.17e-314	-	-	-	V	-	-	-	MATE efflux family protein
BIGFKLDO_01592	4.42e-249	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
BIGFKLDO_01593	0.0	-	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_01594	1.76e-204	murQ	4.2.1.126	-	H	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BIGFKLDO_01595	3.42e-199	-	-	-	K	-	-	-	transcriptional regulator RpiR family
BIGFKLDO_01596	4.84e-197	-	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger family protein
BIGFKLDO_01597	1.58e-81	-	-	-	G	-	-	-	Aldolase
BIGFKLDO_01598	1.04e-286	-	-	-	P	-	-	-	arsenite transmembrane transporter activity
BIGFKLDO_01599	1.85e-265	pdxA	1.1.1.262, 1.1.1.408, 1.1.1.409	-	C	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the PdxA family
BIGFKLDO_01600	1.6e-217	-	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the DapA family
BIGFKLDO_01601	1.76e-277	-	-	-	C	-	-	-	alcohol dehydrogenase
BIGFKLDO_01602	7.39e-303	-	-	-	G	-	-	-	BNR repeat-like domain
BIGFKLDO_01603	8.48e-284	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative sugar-binding N-terminal domain
BIGFKLDO_01604	0.0	-	-	-	T	ko:K02667	ko02020,map02020	ko00000,ko00001,ko00002,ko02022,ko02035	phosphorelay signal transduction system
BIGFKLDO_01605	5.29e-298	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
BIGFKLDO_01606	1.67e-30	-	-	-	L	-	-	-	Helix-turn-helix domain
BIGFKLDO_01607	0.0	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
BIGFKLDO_01608	1.51e-51	-	-	-	-	-	-	-	-
BIGFKLDO_01610	6.39e-50	-	-	-	-	-	-	-	-
BIGFKLDO_01611	3.27e-123	-	-	-	-	-	-	-	-
BIGFKLDO_01612	1.63e-132	-	-	-	-	-	-	-	-
BIGFKLDO_01613	4.05e-112	-	-	-	M	-	-	-	Domain of unknown function (DUF4367)
BIGFKLDO_01614	1.02e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
BIGFKLDO_01615	3.15e-153	-	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma-70 region 2
BIGFKLDO_01616	1.99e-137	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
BIGFKLDO_01617	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
BIGFKLDO_01618	1.02e-169	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
BIGFKLDO_01619	0.0	-	-	CE1	Q	ko:K03932	-	ko00000	Esterase PHB depolymerase
BIGFKLDO_01620	6.34e-276	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribose-phosphate pyrophosphokinase family
BIGFKLDO_01621	7.12e-275	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BIGFKLDO_01622	8.41e-281	-	-	-	T	-	-	-	diguanylate cyclase
BIGFKLDO_01623	5.68e-156	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BIGFKLDO_01625	8.49e-125	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01626	0.0	ispH	1.17.7.4	-	IJM	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BIGFKLDO_01627	2.01e-147	plsC_1	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
BIGFKLDO_01628	1.28e-148	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
BIGFKLDO_01629	5.37e-307	-	-	-	S	ko:K07007	-	ko00000	Flavoprotein family
BIGFKLDO_01630	3.05e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
BIGFKLDO_01631	1.56e-246	-	-	-	G	-	-	-	Major Facilitator Superfamily
BIGFKLDO_01632	1.49e-156	-	-	-	M	-	-	-	Peptidase, M23 family
BIGFKLDO_01633	8.54e-295	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
BIGFKLDO_01634	0.0	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
BIGFKLDO_01635	1.14e-172	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
BIGFKLDO_01636	1.99e-210	-	-	-	P	ko:K10194	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
BIGFKLDO_01637	3.8e-223	-	-	-	P	ko:K02025,ko:K10193	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate ABC transporter membrane protein 1 CUT1 family
BIGFKLDO_01638	0.0	-	-	-	G	ko:K02027,ko:K10192	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
BIGFKLDO_01639	3.34e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
BIGFKLDO_01640	8.11e-152	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BIGFKLDO_01641	1.45e-161	tepA	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score
BIGFKLDO_01642	0.0	spoIIIE	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
BIGFKLDO_01643	0.0	-	-	-	C	-	-	-	UPF0313 protein
BIGFKLDO_01644	1.2e-214	-	-	-	J	ko:K02238	-	ko00000,ko00002,ko02044	Metallo-beta-lactamase domain protein
BIGFKLDO_01645	8.46e-96	-	-	-	-	-	-	-	-
BIGFKLDO_01646	0.0	gltA2	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	citrate synthase
BIGFKLDO_01647	6.63e-95	-	-	-	K	-	-	-	Transcriptional regulator, BlaI MecI CopY family
BIGFKLDO_01648	1.93e-285	alaXL	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Threonine alanine tRNA ligase second additional domain protein
BIGFKLDO_01649	8.11e-191	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
BIGFKLDO_01650	6.15e-40	-	-	-	S	-	-	-	Psort location
BIGFKLDO_01651	4.33e-214	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01652	0.0	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
BIGFKLDO_01653	2.34e-140	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
BIGFKLDO_01654	2.05e-63	azlD	-	-	E	-	-	-	branched-chain amino acid permeases (Azaleucine resistance)
BIGFKLDO_01655	5.56e-245	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
BIGFKLDO_01656	2.88e-190	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	pyridine
BIGFKLDO_01657	3.32e-145	-	-	-	K	ko:K01420	-	ko00000,ko03000	Psort location Cytoplasmic, score
BIGFKLDO_01658	3.33e-242	-	-	-	C	ko:K18471	ko00640,map00640	ko00000,ko00001,ko01000	Aldo/keto reductase family
BIGFKLDO_01659	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BIGFKLDO_01660	3.59e-206	-	-	-	JK	-	-	-	Acetyltransferase (GNAT) family
BIGFKLDO_01661	1.62e-275	-	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain
BIGFKLDO_01662	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
BIGFKLDO_01663	0.0	-	3.1.3.48	-	K	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
BIGFKLDO_01664	1.52e-146	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
BIGFKLDO_01665	1.23e-113	-	-	-	S	ko:K16788	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
BIGFKLDO_01666	4.04e-205	tktA	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, thiamine diphosphate binding domain
BIGFKLDO_01667	1.39e-228	tktB	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyridine binding domain protein
BIGFKLDO_01668	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
BIGFKLDO_01669	1.15e-193	oppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
BIGFKLDO_01670	3.3e-228	oppC	-	-	P	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
BIGFKLDO_01671	4.18e-262	-	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
BIGFKLDO_01672	2.04e-223	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
BIGFKLDO_01673	1.03e-50	-	-	-	-	-	-	-	-
BIGFKLDO_01674	0.0	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
BIGFKLDO_01675	1.1e-98	-	-	-	-	-	-	-	-
BIGFKLDO_01676	4.87e-47	-	-	-	-	-	-	-	-
BIGFKLDO_01677	3.33e-208	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
BIGFKLDO_01678	1.09e-89	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
BIGFKLDO_01679	1.47e-56	rhaA	5.3.1.14	-	G	ko:K01813	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
BIGFKLDO_01680	1.75e-241	rhaA	5.3.1.14	-	G	ko:K01813	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
BIGFKLDO_01681	5.54e-208	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
BIGFKLDO_01682	2.34e-207	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
BIGFKLDO_01683	2.61e-155	effD	-	-	V	-	-	-	MatE
BIGFKLDO_01684	6.56e-149	-	1.1.1.100, 1.1.1.30	-	IQ	ko:K00019,ko:K00059	ko00061,ko00072,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00072,map00333,map00650,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
BIGFKLDO_01685	6.49e-18	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01686	1.23e-309	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
BIGFKLDO_01687	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
BIGFKLDO_01688	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 2
BIGFKLDO_01689	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
BIGFKLDO_01690	3.74e-205	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
BIGFKLDO_01691	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain protein
BIGFKLDO_01692	5.82e-272	-	-	-	G	-	-	-	Major Facilitator Superfamily
BIGFKLDO_01693	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
BIGFKLDO_01694	1.6e-289	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01695	2.83e-110	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
BIGFKLDO_01696	7.82e-240	-	-	-	M	-	-	-	Bacterial extracellular solute-binding protein, family 7
BIGFKLDO_01697	1.97e-84	-	-	-	K	-	-	-	Cupin domain
BIGFKLDO_01699	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
BIGFKLDO_01700	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2264)
BIGFKLDO_01701	4.79e-297	-	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
BIGFKLDO_01702	0.0	-	3.2.1.23, 3.2.1.31	-	G	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolases family 2
BIGFKLDO_01703	2.32e-201	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Carbohydrate ABC transporter membrane protein 2, CUT1 family
BIGFKLDO_01704	4.1e-222	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC transporter
BIGFKLDO_01705	3.18e-299	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Carbohydrate ABC transporter substrate-binding protein, CUT1 family (TC 3.A.1.1.-)
BIGFKLDO_01709	1.72e-105	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
BIGFKLDO_01710	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BIGFKLDO_01711	2.41e-259	-	-	-	S	-	-	-	Acyltransferase family
BIGFKLDO_01712	1.07e-242	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
BIGFKLDO_01713	8.44e-176	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
BIGFKLDO_01714	0.0	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
BIGFKLDO_01715	3.24e-249	dmpA	3.4.11.19	-	EQ	ko:K01266	-	ko00000,ko01000,ko01002	Peptidase family S58
BIGFKLDO_01716	4.77e-305	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01717	2.25e-245	-	-	-	S	-	-	-	AI-2E family transporter
BIGFKLDO_01718	0.0	-	-	-	FG	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
BIGFKLDO_01719	0.0	-	-	-	T	-	-	-	Response regulator receiver domain protein
BIGFKLDO_01720	1.9e-104	-	-	-	F	-	-	-	Belongs to the 5'-nucleotidase family
BIGFKLDO_01721	0.0	apeB	3.4.11.21	-	E	ko:K01267	-	ko00000,ko01000,ko01002,ko04131	M18 family aminopeptidase
BIGFKLDO_01722	0.0	NPD5_3681	-	-	E	-	-	-	amino acid
BIGFKLDO_01723	7.72e-156	-	-	-	K	-	-	-	FCD
BIGFKLDO_01724	3.17e-111	hsp18	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
BIGFKLDO_01725	1.48e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF2500)
BIGFKLDO_01726	1.41e-75	-	-	-	-	-	-	-	-
BIGFKLDO_01727	7.81e-89	-	-	-	S	-	-	-	YjbR
BIGFKLDO_01728	2.42e-194	-	-	-	S	-	-	-	HAD hydrolase, family IIB
BIGFKLDO_01729	9.39e-196	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
BIGFKLDO_01730	3.35e-09	-	-	-	T	-	-	-	Histidine kinase
BIGFKLDO_01733	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_01734	1.33e-190	-	-	-	J	-	-	-	SpoU rRNA Methylase family
BIGFKLDO_01736	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01738	3.86e-196	-	-	-	K	-	-	-	DNA binding
BIGFKLDO_01739	3.49e-132	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
BIGFKLDO_01740	1.68e-50	-	-	-	-	-	-	-	-
BIGFKLDO_01742	1.63e-300	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
BIGFKLDO_01743	1.55e-292	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
BIGFKLDO_01744	1.68e-233	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
BIGFKLDO_01746	7.02e-30	-	-	-	S	-	-	-	ABC-2 family transporter protein
BIGFKLDO_01747	1.39e-195	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
BIGFKLDO_01748	8.2e-81	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
BIGFKLDO_01749	1.14e-297	dapL	2.6.1.83	-	H	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate
BIGFKLDO_01750	1.59e-209	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BIGFKLDO_01751	6.35e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BIGFKLDO_01752	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
BIGFKLDO_01753	1.33e-224	-	-	-	G	-	-	-	Aldose 1-epimerase
BIGFKLDO_01754	1.41e-264	-	-	-	T	-	-	-	Histidine kinase
BIGFKLDO_01755	5.21e-154	-	-	-	T	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BIGFKLDO_01756	3.46e-25	-	-	-	-	-	-	-	-
BIGFKLDO_01757	5.81e-195	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01758	3.48e-190	-	-	-	CO	ko:K06196	-	ko00000,ko02000	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BIGFKLDO_01759	0.0	-	-	-	M	-	-	-	peptidoglycan binding domain protein
BIGFKLDO_01760	3.86e-172	-	-	-	M	-	-	-	peptidoglycan binding domain protein
BIGFKLDO_01761	3.37e-115	-	-	-	C	-	-	-	Flavodoxin domain
BIGFKLDO_01762	6.12e-230	-	1.1.1.29, 1.1.1.399, 1.1.1.95	-	CH	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
BIGFKLDO_01764	1.76e-173	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
BIGFKLDO_01765	2.73e-86	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BIGFKLDO_01766	1.21e-205	-	-	-	T	-	-	-	cheY-homologous receiver domain
BIGFKLDO_01767	8.84e-43	-	-	-	S	-	-	-	Protein conserved in bacteria
BIGFKLDO_01768	5.06e-237	-	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
BIGFKLDO_01769	3.14e-276	-	2.7.1.165	-	G	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	MOFRL family
BIGFKLDO_01771	2.28e-292	-	-	-	M	-	-	-	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BIGFKLDO_01773	4.15e-72	-	-	-	S	-	-	-	No similarity found
BIGFKLDO_01774	5.59e-73	-	-	-	S	-	-	-	SGNH hydrolase-like domain, acetyltransferase AlgX
BIGFKLDO_01775	0.0	-	-	-	M	ko:K19294	-	ko00000	Psort location CytoplasmicMembrane, score
BIGFKLDO_01777	2.68e-09	-	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
BIGFKLDO_01778	0.0	-	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase
BIGFKLDO_01779	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	PFAM DNA gyrase topoisomerase IV, subunit A
BIGFKLDO_01780	1.6e-103	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BIGFKLDO_01781	5.86e-191	fliY1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
BIGFKLDO_01782	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
BIGFKLDO_01783	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
BIGFKLDO_01784	3.67e-294	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
BIGFKLDO_01785	1.31e-288	-	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
BIGFKLDO_01786	6.64e-170	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01787	3.05e-236	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01788	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
BIGFKLDO_01789	3.22e-94	-	-	-	S	-	-	-	NusG domain II
BIGFKLDO_01790	0.0	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
BIGFKLDO_01791	6.35e-176	macB	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
BIGFKLDO_01792	1.27e-273	macB1	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
BIGFKLDO_01793	0.0	-	-	-	F	-	-	-	S-layer homology domain
BIGFKLDO_01794	7.76e-189	comF	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
BIGFKLDO_01796	6.09e-53	-	-	-	-	-	-	-	-
BIGFKLDO_01797	1e-63	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
BIGFKLDO_01798	3.35e-99	-	-	-	KT	ko:K02483	-	ko00000,ko02022	response regulator receiver
BIGFKLDO_01799	3.52e-257	-	-	-	C	-	-	-	succinate dehydrogenase
BIGFKLDO_01800	2.96e-120	-	-	-	M	-	-	-	Peptidase family S41
BIGFKLDO_01802	3.34e-176	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
BIGFKLDO_01803	1.18e-117	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01804	1.87e-305	-	-	-	V	-	-	-	MviN-like protein
BIGFKLDO_01805	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN_bind
BIGFKLDO_01806	8.21e-216	-	-	-	K	-	-	-	LysR substrate binding domain
BIGFKLDO_01807	5.45e-233	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01808	0.0	cstA	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01809	1.86e-215	-	-	-	K	-	-	-	LysR substrate binding domain
BIGFKLDO_01811	3.98e-126	-	-	-	G	-	-	-	Phosphoglycerate mutase family
BIGFKLDO_01812	9.84e-299	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01813	0.0	-	-	-	S	-	-	-	DNA replication and repair protein RecF
BIGFKLDO_01814	9.83e-134	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
BIGFKLDO_01815	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_01818	3.74e-69	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
BIGFKLDO_01819	0.0	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	CBS domain
BIGFKLDO_01821	4.25e-306	-	-	-	V	-	-	-	MATE efflux family protein
BIGFKLDO_01822	3.54e-116	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01823	1.35e-239	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon
BIGFKLDO_01824	0.0	-	3.2.1.122, 3.2.1.86	GH4,GT4	G	ko:K01222,ko:K01232	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
BIGFKLDO_01825	0.0	glvC	2.7.1.199, 2.7.1.208	-	G	ko:K02749,ko:K02750,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_01826	8.07e-191	licT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	Psort location Cytoplasmic, score
BIGFKLDO_01827	5.92e-118	-	-	-	-	-	-	-	-
BIGFKLDO_01828	3.74e-265	-	-	-	C	ko:K07138	-	ko00000	Psort location Cytoplasmic, score
BIGFKLDO_01830	3.89e-195	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
BIGFKLDO_01831	3.16e-232	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
BIGFKLDO_01832	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
BIGFKLDO_01833	9.51e-240	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein, MreB Mrl family
BIGFKLDO_01834	1.8e-59	-	-	-	C	-	-	-	decarboxylase gamma
BIGFKLDO_01835	2.13e-276	gcdB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	decarboxylase beta subunit
BIGFKLDO_01836	6.62e-164	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
BIGFKLDO_01837	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Psort location CytoplasmicMembrane, score
BIGFKLDO_01838	7.41e-65	-	-	-	S	-	-	-	protein, YerC YecD
BIGFKLDO_01839	2.71e-72	-	-	-	-	-	-	-	-
BIGFKLDO_01840	7.2e-130	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_01841	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
BIGFKLDO_01843	6.86e-174	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_01844	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
BIGFKLDO_01845	2.37e-117	-	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Psort location CytoplasmicMembrane, score
BIGFKLDO_01846	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BIGFKLDO_01847	1.72e-142	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
BIGFKLDO_01848	7.18e-182	-	-	-	Q	-	-	-	Methyltransferase domain protein
BIGFKLDO_01849	9.63e-196	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BIGFKLDO_01850	4.69e-261	yqfD	-	-	M	ko:K06438	-	ko00000	Putative stage IV sporulation protein YqfD
BIGFKLDO_01852	2.92e-257	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
BIGFKLDO_01853	6.28e-249	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BIGFKLDO_01854	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	phenylalanyl-tRNA synthetase (beta subunit)
BIGFKLDO_01857	3.49e-63	-	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
BIGFKLDO_01858	8.52e-208	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0160)
BIGFKLDO_01859	1.11e-148	-	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotate phosphoribosyltransferase
BIGFKLDO_01860	2.84e-301	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01861	6.08e-314	-	-	-	F	-	-	-	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BIGFKLDO_01862	1.16e-202	-	-	-	S	-	-	-	Putative esterase
BIGFKLDO_01863	7.51e-192	-	-	-	S	-	-	-	Putative esterase
BIGFKLDO_01864	2.76e-273	ilvE	2.6.1.42, 4.1.3.38	-	E	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
BIGFKLDO_01865	1.46e-156	-	-	-	S	-	-	-	IA, variant 3
BIGFKLDO_01866	0.0	-	3.1.3.5, 3.6.1.45	-	F	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
BIGFKLDO_01867	6.36e-231	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_01868	1.04e-217	-	-	-	Q	-	-	-	FAH family
BIGFKLDO_01869	3.36e-118	yajL	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
BIGFKLDO_01870	1.66e-61	-	-	-	S	-	-	-	Trp repressor protein
BIGFKLDO_01871	1.87e-117	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
BIGFKLDO_01872	4.33e-116	nfrA2	-	-	C	-	-	-	Nitroreductase family
BIGFKLDO_01873	1.62e-64	-	-	-	G	-	-	-	Ricin-type beta-trefoil
BIGFKLDO_01874	2.35e-127	mutX	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Psort location Cytoplasmic, score 8.96
BIGFKLDO_01875	0.0	nagE	2.7.1.193	-	G	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_01876	6.09e-276	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BIGFKLDO_01877	3.07e-119	ptbA	-	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
BIGFKLDO_01878	3.37e-273	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
BIGFKLDO_01879	2.03e-250	-	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
BIGFKLDO_01881	2.15e-166	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_01882	6.55e-65	-	-	-	S	-	-	-	regulation of response to stimulus
BIGFKLDO_01883	1.76e-164	-	-	-	K	-	-	-	Helix-turn-helix
BIGFKLDO_01887	1.43e-306	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	xanthine uracil permease family protein K06901
BIGFKLDO_01888	0.0	-	-	-	S	ko:K06972	-	ko00000,ko01000,ko01002	Peptidase M16C associated
BIGFKLDO_01890	1.59e-222	mglC	-	-	G	ko:K10541	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
BIGFKLDO_01891	0.0	mglA	3.6.3.17	-	G	ko:K10542	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC-type sugar transport system, ATPase component
BIGFKLDO_01892	1.88e-230	-	-	-	G	ko:K10540	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG COG1879 ABC-type sugar transport system, periplasmic component
BIGFKLDO_01894	0.0	-	-	-	S	-	-	-	Terminase-like family
BIGFKLDO_01895	0.0	-	-	-	-	-	-	-	-
BIGFKLDO_01896	3.78e-131	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
BIGFKLDO_01897	3.72e-239	-	-	-	-	-	-	-	-
BIGFKLDO_01900	0.0	-	-	-	-	-	-	-	-
BIGFKLDO_01902	6.72e-234	-	-	-	-	-	-	-	-
BIGFKLDO_01905	4.9e-83	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01906	1.74e-140	-	-	-	S	-	-	-	Protein of unknown function (DUF1643)
BIGFKLDO_01907	0.0	-	-	-	S	-	-	-	ABC transporter substrate-binding protein PnrA-like
BIGFKLDO_01908	6.09e-128	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase superfamily domain
BIGFKLDO_01909	9.17e-44	-	-	-	-	-	-	-	-
BIGFKLDO_01910	0.0	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
BIGFKLDO_01911	5.71e-32	-	-	-	-	-	-	-	-
BIGFKLDO_01912	7.05e-270	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
BIGFKLDO_01914	0.0	-	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01119,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
BIGFKLDO_01915	1.02e-236	-	-	-	-	-	-	-	-
BIGFKLDO_01917	9.4e-133	-	-	-	-	-	-	-	-
BIGFKLDO_01919	2.8e-175	-	-	-	S	ko:K06872	-	ko00000	Pfam:TPM
BIGFKLDO_01920	5.53e-266	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
BIGFKLDO_01922	4.56e-209	-	-	-	S	-	-	-	Domain of unknown function (DUF4428)
BIGFKLDO_01923	8.11e-292	-	-	-	S	-	-	-	SPFH domain-Band 7 family
BIGFKLDO_01925	0.0	-	-	-	-	-	-	-	-
BIGFKLDO_01926	8.72e-278	-	-	-	-	-	-	-	-
BIGFKLDO_01928	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	COG COG1653 ABC-type sugar transport system, periplasmic component
BIGFKLDO_01929	0.0	-	-	-	KT	-	-	-	transcriptional regulator LuxR family
BIGFKLDO_01930	2.11e-149	-	-	-	S	ko:K06889	-	ko00000	Psort location Cytoplasmic, score 8.87
BIGFKLDO_01931	2.71e-180	yoaP	-	-	E	-	-	-	YoaP-like
BIGFKLDO_01932	1.72e-177	-	-	-	C	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase catalytic
BIGFKLDO_01933	7.7e-165	-	1.4.1.21	-	S	ko:K06989	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	homoserine dehydrogenase
BIGFKLDO_01934	8.36e-44	-	-	-	U	-	-	-	domain, Protein
BIGFKLDO_01935	3.85e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BIGFKLDO_01936	5.29e-145	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
BIGFKLDO_01937	1.26e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
BIGFKLDO_01938	4.2e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BIGFKLDO_01939	2.9e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BIGFKLDO_01940	1.01e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BIGFKLDO_01941	9.39e-166	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BIGFKLDO_01942	2.02e-101	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BIGFKLDO_01943	9.04e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
BIGFKLDO_01944	1.42e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BIGFKLDO_01945	1.31e-81	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BIGFKLDO_01946	1.66e-71	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BIGFKLDO_01947	2.49e-128	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BIGFKLDO_01948	1.67e-38	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BIGFKLDO_01949	2.77e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BIGFKLDO_01950	1.05e-130	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BIGFKLDO_01951	1.14e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BIGFKLDO_01952	6.22e-108	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BIGFKLDO_01953	1.83e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein
BIGFKLDO_01954	2.45e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
BIGFKLDO_01955	3.22e-288	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
BIGFKLDO_01956	5.7e-146	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
BIGFKLDO_01957	2.58e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
BIGFKLDO_01958	8.01e-59	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BIGFKLDO_01959	7.03e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
BIGFKLDO_01960	3.34e-80	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BIGFKLDO_01961	1.25e-88	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BIGFKLDO_01962	4.36e-136	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BIGFKLDO_01963	3.11e-222	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BIGFKLDO_01964	2.75e-72	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
BIGFKLDO_01965	2.09e-303	-	-	-	S	-	-	-	Tetratricopeptide repeat
BIGFKLDO_01966	8.65e-162	-	-	-	K	-	-	-	response regulator receiver
BIGFKLDO_01967	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
BIGFKLDO_01968	4.64e-227	prmC	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_01969	2.48e-226	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
BIGFKLDO_01970	8.84e-266	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BIGFKLDO_01971	1.14e-102	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
BIGFKLDO_01972	0.0	rimO	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
BIGFKLDO_01973	2.73e-134	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BIGFKLDO_01976	9.25e-217	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BIGFKLDO_01977	5.4e-294	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
BIGFKLDO_01978	9.07e-198	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
BIGFKLDO_01979	3.27e-295	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BIGFKLDO_01980	1.17e-219	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BIGFKLDO_01981	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
BIGFKLDO_01982	4.01e-301	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
BIGFKLDO_01983	1.76e-236	-	-	-	S	ko:K07035	-	ko00000	Psort location CytoplasmicMembrane, score
BIGFKLDO_01984	1.25e-283	-	-	-	M	-	-	-	hydrolase, family 25
BIGFKLDO_01985	2.26e-135	-	-	-	S	-	-	-	Domain of unknown function (DUF4830)
BIGFKLDO_01986	1.21e-53	-	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier, HPr family
BIGFKLDO_01987	0.0	ptsP	2.7.3.9, 2.7.9.2	-	G	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BIGFKLDO_01988	4.87e-113	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
BIGFKLDO_01989	5.06e-152	-	-	-	S	-	-	-	Putative zinc-finger
BIGFKLDO_01990	3.26e-312	-	-	-	M	-	-	-	Peptidase, M23 family
BIGFKLDO_01991	3.6e-30	-	-	-	-	-	-	-	-
BIGFKLDO_01992	4.72e-211	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Psort location Cytoplasmic, score
BIGFKLDO_01993	1.11e-62	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA synthetase
BIGFKLDO_01996	7.36e-250	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
BIGFKLDO_01997	1.78e-151	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
BIGFKLDO_01998	4.34e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
BIGFKLDO_01999	1.35e-116	-	-	-	T	-	-	-	Nacht domain
BIGFKLDO_02000	1.14e-276	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_02005	3.44e-146	-	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Psort location Cytoplasmic, score
BIGFKLDO_02006	4.17e-172	tsaA	-	-	S	-	-	-	Methyltransferase, YaeB family
BIGFKLDO_02007	1.05e-195	-	-	-	K	-	-	-	LysR substrate binding domain
BIGFKLDO_02008	2.96e-216	-	-	-	N	-	-	-	Bacterial Ig-like domain 2
BIGFKLDO_02009	3.55e-127	rbr	-	-	C	-	-	-	Rubrerythrin
BIGFKLDO_02010	0.0	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_02011	3.64e-180	yacO	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BIGFKLDO_02012	2.85e-207	fba	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
BIGFKLDO_02013	5.7e-199	-	-	-	H	-	-	-	Leucine carboxyl methyltransferase
BIGFKLDO_02014	1.35e-07	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
BIGFKLDO_02015	9.82e-244	-	-	-	P	-	-	-	Citrate transporter
BIGFKLDO_02016	2.11e-200	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
BIGFKLDO_02017	1.26e-315	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
BIGFKLDO_02018	3.09e-212	-	-	-	K	-	-	-	LysR substrate binding domain protein
BIGFKLDO_02019	3.05e-234	-	-	-	G	-	-	-	TRAP transporter solute receptor, DctP family
BIGFKLDO_02020	1.9e-281	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_02021	9.27e-121	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_02022	6.99e-245	-	-	-	G	-	-	-	TRAP transporter solute receptor, DctP family
BIGFKLDO_02023	2.03e-179	-	-	-	K	-	-	-	Response regulator receiver domain
BIGFKLDO_02024	0.0	-	-	-	T	-	-	-	Histidine kinase
BIGFKLDO_02025	6.9e-157	-	-	-	K	-	-	-	Cyclic nucleotide-binding domain protein
BIGFKLDO_02026	3.1e-158	-	-	-	C	-	-	-	4Fe-4S binding domain protein
BIGFKLDO_02027	0.0	-	-	-	T	-	-	-	Response regulator receiver domain protein
BIGFKLDO_02029	2.55e-83	cas6	-	-	S	-	-	-	CRISPR-associated endoribonuclease Cas6
BIGFKLDO_02030	1.88e-94	csm5	-	-	L	ko:K19140	-	ko00000,ko02048	RAMP superfamily
BIGFKLDO_02031	1.03e-124	csm4	-	-	L	ko:K19139	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm4 family
BIGFKLDO_02032	3.37e-99	csm3	-	-	L	ko:K09002	-	ko00000,ko02048	RAMP superfamily
BIGFKLDO_02033	1.73e-29	csm2	-	-	L	ko:K19138	-	ko00000,ko02048	Pfam:DUF310
BIGFKLDO_02034	4.04e-208	csm1	-	-	J	ko:K07016	-	ko00000,ko02048	crispr-associated protein
BIGFKLDO_02037	5.82e-59	-	-	-	S	-	-	-	CRISPR-associated (Cas) DxTHG family
BIGFKLDO_02039	2.36e-143	-	-	-	L	-	-	-	CRISPR-associated (Cas) DxTHG family
BIGFKLDO_02040	1.59e-64	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
BIGFKLDO_02041	1.03e-66	-	-	-	L	-	-	-	helicase
BIGFKLDO_02042	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
BIGFKLDO_02043	1.98e-297	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
BIGFKLDO_02044	0.0	-	-	-	S	-	-	-	Heparinase II/III-like protein
BIGFKLDO_02045	6.18e-195	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_02046	0.0	-	-	-	-	-	-	-	-
BIGFKLDO_02047	3.41e-119	-	-	-	K	-	-	-	DNA-binding transcription factor activity
BIGFKLDO_02048	7.76e-314	-	-	-	S	-	-	-	Putative threonine/serine exporter
BIGFKLDO_02049	6.12e-179	-	-	-	S	-	-	-	Domain of unknown function (DUF4866)
BIGFKLDO_02050	3.65e-37	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
BIGFKLDO_02051	2.07e-117	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
BIGFKLDO_02052	4.93e-24	-	3.2.1.17	-	G	ko:K01185	-	ko00000,ko01000	lysozyme
BIGFKLDO_02054	6.54e-32	-	-	-	K	ko:K03086,ko:K03091	-	ko00000,ko03021	Sigma-70 region 2
BIGFKLDO_02055	1.47e-139	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
BIGFKLDO_02056	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
BIGFKLDO_02057	6.34e-142	nrdG	1.97.1.4	-	C	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BIGFKLDO_02058	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
BIGFKLDO_02059	9.72e-254	-	-	-	S	-	-	-	Glycosyltransferase like family 2
BIGFKLDO_02060	9.09e-282	-	-	-	P	-	-	-	Transporter, CPA2 family
BIGFKLDO_02061	2.58e-54	-	-	-	K	ko:K06284	-	ko00000,ko03000	Transcriptional regulator, AbrB family
BIGFKLDO_02062	5.24e-231	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
BIGFKLDO_02063	3.3e-211	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
BIGFKLDO_02064	3.96e-154	-	-	-	KT	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
BIGFKLDO_02065	8.16e-207	-	-	-	S	-	-	-	TraX protein
BIGFKLDO_02066	2.61e-114	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
BIGFKLDO_02067	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
BIGFKLDO_02068	4.06e-108	-	-	-	-	-	-	-	-
BIGFKLDO_02070	1.64e-90	-	1.15.1.2	-	C	ko:K05919	-	ko00000,ko01000	Superoxide reductase
BIGFKLDO_02071	5.03e-256	-	-	-	T	-	-	-	domain protein
BIGFKLDO_02072	3.43e-156	-	-	-	S	-	-	-	von Willebrand factor (vWF) type A domain
BIGFKLDO_02073	7.51e-159	nnrE	5.1.99.6	-	G	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
BIGFKLDO_02074	5.52e-241	-	-	-	S	-	-	-	domain protein
BIGFKLDO_02075	7.72e-180	-	-	-	C	-	-	-	4Fe-4S binding domain
BIGFKLDO_02076	7.89e-187	-	-	-	S	-	-	-	Putative cyclase
BIGFKLDO_02077	3.86e-38	ywhH	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Cys-tRNA(Pro) hydrolase activity
BIGFKLDO_02078	7.77e-196	-	-	-	-	-	-	-	-
BIGFKLDO_02079	7.04e-174	gufA	-	-	P	ko:K07238	-	ko00000,ko02000	Metal cation transporter, ZIP family
BIGFKLDO_02080	9.65e-95	-	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
BIGFKLDO_02081	1.3e-156	-	-	-	S	-	-	-	hydrolase of the alpha beta superfamily
BIGFKLDO_02082	7.18e-145	-	-	-	S	-	-	-	YheO-like PAS domain
BIGFKLDO_02083	2.17e-81	TdcF	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
BIGFKLDO_02084	3.31e-301	-	-	-	S	-	-	-	Belongs to the UPF0597 family
BIGFKLDO_02085	4.28e-274	-	-	-	C	-	-	-	Sodium:dicarboxylate symporter family
BIGFKLDO_02086	3.41e-278	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BIGFKLDO_02087	4.08e-291	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	PFAM Aminotransferase class I and II
BIGFKLDO_02088	2.22e-299	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
BIGFKLDO_02090	2.12e-175	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
BIGFKLDO_02091	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BIGFKLDO_02092	1.14e-74	hinT	-	-	FG	ko:K02503	-	ko00000,ko04147	Psort location Cytoplasmic, score
BIGFKLDO_02093	6.61e-123	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Psort location Cytoplasmic, score
BIGFKLDO_02094	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Psort location CytoplasmicMembrane, score
BIGFKLDO_02095	6.65e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Psort location Cytoplasmic, score
BIGFKLDO_02096	6.2e-140	rnmV	3.1.26.8	-	L	ko:K05985	-	ko00000,ko01000	Ribonuclease M5
BIGFKLDO_02097	1.85e-75	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
BIGFKLDO_02098	2.76e-90	-	-	-	I	-	-	-	Alpha/beta hydrolase family
BIGFKLDO_02099	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
BIGFKLDO_02100	8.42e-299	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
BIGFKLDO_02101	0.0	-	-	-	S	-	-	-	Heparinase II/III-like protein
BIGFKLDO_02102	4.35e-195	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
BIGFKLDO_02103	0.0	-	-	-	-	-	-	-	-
BIGFKLDO_02105	7.75e-106	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
BIGFKLDO_02106	5.02e-87	-	-	-	S	-	-	-	Putative redox-active protein (C_GCAxxG_C_C)
BIGFKLDO_02107	2.35e-106	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BIGFKLDO_02108	1.26e-112	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
BIGFKLDO_02109	8.49e-157	-	-	-	S	-	-	-	Domain of unknown function (DUF5058)
BIGFKLDO_02110	6.22e-163	-	-	-	-	-	-	-	-
BIGFKLDO_02111	2.16e-204	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
BIGFKLDO_02113	7.69e-73	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
BIGFKLDO_02115	5.75e-63	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
BIGFKLDO_02116	5.98e-115	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
BIGFKLDO_02117	1.15e-174	-	-	-	S	ko:K06940	-	ko00000	Psort location Cytoplasmic, score 8.96
BIGFKLDO_02118	7.5e-208	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
BIGFKLDO_02119	2.22e-192	-	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Branched-chain amino acid ABC transporter, permease protein
BIGFKLDO_02120	9.65e-179	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
BIGFKLDO_02125	2.53e-147	-	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Psort location Cytoplasmic, score
BIGFKLDO_02126	2.48e-25	-	-	-	-	-	-	-	-
BIGFKLDO_02127	2.61e-171	tsaA	-	-	S	-	-	-	Methyltransferase, YaeB family
BIGFKLDO_02128	6.97e-208	-	-	-	K	-	-	-	LysR substrate binding domain
BIGFKLDO_02129	1.04e-96	-	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
BIGFKLDO_02130	4.73e-168	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
BIGFKLDO_02131	1.3e-169	-	-	-	S	-	-	-	Replication initiator protein A
BIGFKLDO_02133	1.47e-25	-	-	-	K	-	-	-	MarR family
BIGFKLDO_02134	3.24e-124	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
BIGFKLDO_02135	1.36e-215	rluC	5.4.99.24	-	J	ko:K06179	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
BIGFKLDO_02136	1.17e-248	lldD	-	-	C	-	-	-	FMN-dependent dehydrogenase
BIGFKLDO_02138	1.72e-190	-	-	-	-	-	-	-	-
BIGFKLDO_02139	2.33e-115	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
BIGFKLDO_02140	3.57e-210	-	-	-	S	ko:K03453	-	ko00000	Psort location CytoplasmicMembrane, score
BIGFKLDO_02141	4.75e-91	-	1.15.1.2	-	C	ko:K05919	-	ko00000,ko01000	Superoxide reductase
BIGFKLDO_02142	2.52e-237	-	-	-	S	-	-	-	domain protein
BIGFKLDO_02143	3.48e-92	fucO	1.1.1.77	-	C	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
BIGFKLDO_02144	3.82e-316	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BIGFKLDO_02145	2.43e-199	-	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger family protein
BIGFKLDO_02146	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
BIGFKLDO_02147	7.41e-45	-	-	-	C	-	-	-	Heavy metal-associated domain protein
BIGFKLDO_02148	1.67e-72	ziaR	-	-	K	ko:K21903	-	ko00000,ko03000	regulatory protein, arsR
BIGFKLDO_02149	1.59e-275	-	-	-	M	-	-	-	Phosphotransferase enzyme family
BIGFKLDO_02150	7.56e-208	-	-	-	K	-	-	-	transcriptional regulator AraC family