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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HAPGPGAE_00001	7.69e-73	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HAPGPGAE_00003	5.75e-63	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HAPGPGAE_00004	5.98e-115	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HAPGPGAE_00005	1.15e-174	-	-	-	S	ko:K06940	-	ko00000	Psort location Cytoplasmic, score 8.96
HAPGPGAE_00006	7.5e-208	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
HAPGPGAE_00007	2.22e-192	-	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Branched-chain amino acid ABC transporter, permease protein
HAPGPGAE_00008	9.65e-179	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HAPGPGAE_00009	1.04e-274	-	2.7.1.45	-	H	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Kinase, PfkB family
HAPGPGAE_00010	5.64e-227	PflX	1.97.1.4	-	C	ko:K04070	-	ko00000,ko01000	pyruvate formate lyase activating
HAPGPGAE_00011	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
HAPGPGAE_00012	4.77e-289	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAPGPGAE_00013	8.08e-190	yycJ	-	-	S	-	-	-	Metallo-beta-lactamase domain protein
HAPGPGAE_00014	1.36e-220	dnaC	-	-	L	ko:K02315	-	ko00000,ko03032	DNA replication protein
HAPGPGAE_00015	3.61e-214	dnaD	-	-	-	ko:K02086	-	ko00000	-
HAPGPGAE_00016	1.53e-89	-	-	-	-	-	-	-	-
HAPGPGAE_00018	8.09e-33	-	-	-	S	-	-	-	Transglycosylase associated protein
HAPGPGAE_00019	1.29e-165	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HAPGPGAE_00020	4.76e-307	yrvN	-	-	L	ko:K07478	-	ko00000	ATPase, AAA family
HAPGPGAE_00021	7.02e-94	-	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HAPGPGAE_00022	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HAPGPGAE_00023	1.79e-92	-	-	-	S	-	-	-	Belongs to the UPF0342 family
HAPGPGAE_00024	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HAPGPGAE_00025	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HAPGPGAE_00026	4.03e-178	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HAPGPGAE_00027	2.78e-308	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAPGPGAE_00028	3.29e-104	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HAPGPGAE_00029	5.69e-195	-	-	-	S	-	-	-	S4 domain protein
HAPGPGAE_00030	5.01e-135	-	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HAPGPGAE_00031	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HAPGPGAE_00032	4.97e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HAPGPGAE_00033	1.89e-228	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HAPGPGAE_00034	2.12e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HAPGPGAE_00035	9.19e-76	-	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
HAPGPGAE_00036	0.0	ppk	2.7.4.1	-	H	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HAPGPGAE_00037	8.66e-113	-	-	-	M	-	-	-	Peptidase family M23
HAPGPGAE_00038	1.06e-105	-	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Peptidase M50
HAPGPGAE_00039	0.0	-	-	-	C	-	-	-	Radical SAM domain protein
HAPGPGAE_00040	1.42e-132	-	-	-	S	-	-	-	Radical SAM-linked protein
HAPGPGAE_00041	6.76e-73	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HAPGPGAE_00042	3.25e-125	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HAPGPGAE_00043	5.17e-220	ylqF	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HAPGPGAE_00044	1.63e-152	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAPGPGAE_00045	2.18e-80	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
HAPGPGAE_00046	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HAPGPGAE_00047	5.89e-161	-	-	-	S	ko:K07099	-	ko00000	Ser Thr phosphatase family protein
HAPGPGAE_00048	1.9e-295	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HAPGPGAE_00049	3.34e-139	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HAPGPGAE_00050	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HAPGPGAE_00051	0.0	-	-	-	EK	-	-	-	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HAPGPGAE_00052	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HAPGPGAE_00053	4.32e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HAPGPGAE_00055	2.86e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HAPGPGAE_00056	0.0	-	-	-	EG	ko:K06295	-	ko00000	spore germination protein
HAPGPGAE_00059	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HAPGPGAE_00060	1.13e-154	phoB	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator receiver domain protein
HAPGPGAE_00061	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Na Pi-cotransporter II-like protein
HAPGPGAE_00062	3.35e-218	hprK	-	-	H	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HAPGPGAE_00063	4.57e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HAPGPGAE_00064	4.38e-186	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HAPGPGAE_00065	8.52e-216	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HAPGPGAE_00066	0.0	dnaE	2.7.7.7	-	L	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
HAPGPGAE_00067	2.6e-233	pfkA	2.7.1.11	-	H	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HAPGPGAE_00068	3.56e-86	-	-	-	S	-	-	-	YjbR
HAPGPGAE_00069	2.45e-47	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00070	5.91e-75	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00071	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HAPGPGAE_00072	2.65e-152	-	-	-	E	-	-	-	AzlC protein
HAPGPGAE_00073	3.04e-59	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HAPGPGAE_00074	5.77e-182	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HAPGPGAE_00075	1.2e-301	pbuX	-	-	F	ko:K03458	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_00076	1.36e-137	ygfJ	2.7.7.76	-	S	ko:K07141	ko00790,map00790	ko00000,ko00001,ko01000	MobA-like NTP transferase domain
HAPGPGAE_00077	1.08e-176	-	-	-	C	-	-	-	FAD binding domain in molybdopterin dehydrogenase
HAPGPGAE_00078	2.6e-111	hcrC	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	[2Fe-2S] binding domain
HAPGPGAE_00079	0.0	xdhD	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00080	9.75e-163	yqeC	-	-	H	-	-	-	selenium-dependent hydroxylase accessory protein YqeC
HAPGPGAE_00081	4.73e-242	selD	2.7.9.3	-	H	ko:K01008	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000,ko03016	Synthesizes selenophosphate from selenide and ATP
HAPGPGAE_00082	1.45e-136	yedF	-	-	O	ko:K04085	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	DsrE/DsrF-like family
HAPGPGAE_00083	1.43e-208	csd	-	-	E	-	-	-	cysteine desulfurase family protein
HAPGPGAE_00084	2.5e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF3343)
HAPGPGAE_00085	1.77e-240	-	-	-	O	ko:K07402	-	ko00000	XdhC and CoxI family
HAPGPGAE_00086	2.69e-188	-	-	-	S	ko:K07402	-	ko00000	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HAPGPGAE_00088	9.97e-119	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
HAPGPGAE_00089	1.17e-67	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HAPGPGAE_00090	6.24e-212	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein
HAPGPGAE_00091	1.95e-114	ybeY	3.5.4.5	-	S	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HAPGPGAE_00092	1.09e-199	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HAPGPGAE_00094	1.56e-176	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HAPGPGAE_00095	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HAPGPGAE_00096	8.73e-131	-	-	-	M	-	-	-	N-acetylmuramoyl-L-alanine amidase
HAPGPGAE_00097	3.74e-284	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HAPGPGAE_00098	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HAPGPGAE_00101	5.34e-64	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase, YajC subunit
HAPGPGAE_00102	4.55e-290	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HAPGPGAE_00103	1.43e-249	queA	2.4.99.17	-	H	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HAPGPGAE_00104	1.53e-266	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartate-semialdehyde dehydrogenase family
HAPGPGAE_00105	7.01e-213	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAPGPGAE_00106	2.22e-182	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HAPGPGAE_00107	2.38e-310	capA	-	-	M	ko:K07282	-	ko00000	Capsule synthesis protein
HAPGPGAE_00108	1.9e-99	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HAPGPGAE_00109	2.36e-130	ptbA	-	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system
HAPGPGAE_00110	1.1e-296	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HAPGPGAE_00111	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HAPGPGAE_00112	6.8e-110	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HAPGPGAE_00113	3.18e-202	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HAPGPGAE_00114	8.86e-176	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HAPGPGAE_00115	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HAPGPGAE_00116	1.39e-101	-	-	-	S	ko:K09775	-	ko00000	Divergent PAP2 family
HAPGPGAE_00117	1.98e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HAPGPGAE_00118	7e-36	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAPGPGAE_00119	2.32e-208	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAPGPGAE_00120	1.4e-166	gcp1	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HAPGPGAE_00121	9.59e-101	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAPGPGAE_00122	4.91e-78	asp	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HAPGPGAE_00123	1.84e-120	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
HAPGPGAE_00124	4.16e-61	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HAPGPGAE_00126	1.92e-240	spoIIIAE	-	-	S	ko:K06394	-	ko00000	Stage III sporulation protein AE (spore_III_AE)
HAPGPGAE_00128	1.78e-30	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HAPGPGAE_00130	2.4e-113	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HAPGPGAE_00131	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HAPGPGAE_00132	0.0	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00133	1.35e-149	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HAPGPGAE_00134	4.56e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HAPGPGAE_00135	0.0	prkC	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HAPGPGAE_00136	1.45e-181	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	serine threonine protein phosphatase
HAPGPGAE_00137	4.97e-249	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HAPGPGAE_00138	8.57e-306	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HAPGPGAE_00139	5.42e-226	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HAPGPGAE_00140	6.9e-129	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HAPGPGAE_00141	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HAPGPGAE_00142	1.04e-129	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HAPGPGAE_00143	5.98e-55	NPD7_560	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HAPGPGAE_00144	7.15e-199	yicC	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00145	1.66e-73	-	-	-	S	-	-	-	Helix-turn-helix of DDE superfamily endonuclease
HAPGPGAE_00146	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Pyruvate carboxylase, C-terminal domain subunit K01960
HAPGPGAE_00147	1.09e-33	gcdC	-	-	I	-	-	-	Biotin-requiring enzyme
HAPGPGAE_00148	3.81e-268	-	-	-	I	-	-	-	Carboxyl transferase domain
HAPGPGAE_00149	2.61e-207	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HAPGPGAE_00150	1.78e-211	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HAPGPGAE_00151	5.42e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HAPGPGAE_00152	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00153	1.04e-64	-	-	-	S	-	-	-	sporulation protein, YlmC YmxH family
HAPGPGAE_00154	7.56e-148	-	-	-	S	ko:K07025	-	ko00000	IA, variant 3
HAPGPGAE_00155	2.31e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HAPGPGAE_00156	3.55e-99	-	-	-	C	-	-	-	Flavodoxin
HAPGPGAE_00157	5.68e-118	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00158	3.08e-308	yhbU_1	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HAPGPGAE_00159	8.49e-265	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HAPGPGAE_00160	7.44e-190	-	-	-	-	-	-	-	-
HAPGPGAE_00161	3.17e-163	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	thymidylate kinase
HAPGPGAE_00162	1.56e-181	thyX	2.1.1.148	-	H	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	ko00000,ko00001,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
HAPGPGAE_00163	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HAPGPGAE_00164	6.35e-126	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HAPGPGAE_00165	5e-174	-	-	-	K	ko:K03710	-	ko00000,ko03000	Psort location Cytoplasmic, score
HAPGPGAE_00166	3.13e-224	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HAPGPGAE_00167	4.43e-100	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HAPGPGAE_00168	1.38e-309	-	-	-	T	-	-	-	Histidine kinase
HAPGPGAE_00169	6.13e-174	-	-	-	K	-	-	-	LytTr DNA-binding domain
HAPGPGAE_00170	4.24e-292	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HAPGPGAE_00171	3.01e-187	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HAPGPGAE_00172	2.54e-87	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HAPGPGAE_00173	2.05e-148	-	-	-	-	-	-	-	-
HAPGPGAE_00174	4.64e-124	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HAPGPGAE_00175	1.19e-135	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HAPGPGAE_00176	1.06e-157	-	-	-	S	-	-	-	peptidase M50
HAPGPGAE_00177	1.85e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HAPGPGAE_00178	1.08e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF4250)
HAPGPGAE_00179	5.07e-188	-	-	-	S	-	-	-	Putative esterase
HAPGPGAE_00180	8.96e-79	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
HAPGPGAE_00181	0.0	copA	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
HAPGPGAE_00182	3.67e-131	rbr3A	-	-	C	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00183	2.49e-310	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_00184	1.76e-258	-	2.8.1.7	-	H	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	aminotransferase class V
HAPGPGAE_00185	1.48e-291	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HAPGPGAE_00186	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HAPGPGAE_00187	1.14e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HAPGPGAE_00188	3.02e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HAPGPGAE_00189	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAPGPGAE_00190	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAPGPGAE_00191	1.07e-241	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HAPGPGAE_00192	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HAPGPGAE_00193	7.82e-239	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the dGTPase family. Type 2 subfamily
HAPGPGAE_00194	2.47e-129	yvyE	-	-	S	-	-	-	YigZ family
HAPGPGAE_00195	2.38e-223	-	-	-	M	-	-	-	Cysteine-rich secretory protein family
HAPGPGAE_00196	1.51e-259	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HAPGPGAE_00197	9.44e-190	-	1.3.1.108	-	C	ko:K03521,ko:K22431	-	ko00000,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_00198	3.01e-274	bcd	1.3.8.1	-	C	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	Acyl-CoA dehydrogenase, C-terminal domain
HAPGPGAE_00199	6.21e-208	hbd	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HAPGPGAE_00200	5.43e-183	crt	4.2.1.17	-	I	ko:K01715	ko00650,ko01200,map00650,map01200	ko00000,ko00001,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HAPGPGAE_00201	1.65e-286	thlA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HAPGPGAE_00202	4.65e-123	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HAPGPGAE_00203	0.0	cat	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
HAPGPGAE_00204	4.66e-266	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00205	2.51e-31	-	-	-	-	-	-	-	-
HAPGPGAE_00206	0.0	-	-	-	C	-	-	-	Radical SAM domain protein
HAPGPGAE_00207	6.19e-107	-	-	-	K	-	-	-	dihydroxyacetone kinase regulator
HAPGPGAE_00208	6.84e-185	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HAPGPGAE_00209	1.1e-184	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HAPGPGAE_00210	7.08e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HAPGPGAE_00211	1.37e-99	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HAPGPGAE_00212	9.75e-315	ynbB	-	-	P	-	-	-	Cystathionine beta-lyase family protein involved in aluminum resistance
HAPGPGAE_00213	4.64e-132	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HAPGPGAE_00214	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HAPGPGAE_00215	5.41e-285	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HAPGPGAE_00217	7.24e-284	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00218	5.19e-269	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
HAPGPGAE_00219	1.24e-224	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HAPGPGAE_00220	3.45e-265	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HAPGPGAE_00221	6.2e-129	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	acetyltransferase (GNAT) family
HAPGPGAE_00222	5.09e-129	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HAPGPGAE_00223	2.21e-100	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_00224	1.02e-190	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HAPGPGAE_00225	1.17e-115	-	-	-	S	-	-	-	TIGRFAM C_GCAxxG_C_C family
HAPGPGAE_00226	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HAPGPGAE_00227	1.78e-244	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00228	3.52e-311	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family
HAPGPGAE_00229	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, C-terminal domain
HAPGPGAE_00230	7.62e-171	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HAPGPGAE_00231	0.0	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HAPGPGAE_00232	1.9e-172	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
HAPGPGAE_00233	4.67e-264	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_00234	3.45e-180	-	-	-	HP	-	-	-	small periplasmic lipoprotein
HAPGPGAE_00235	1.17e-271	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HAPGPGAE_00236	4.2e-221	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAPGPGAE_00237	0.0	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HAPGPGAE_00238	3.54e-179	cobM	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	precorrin-4 C11-methyltransferase
HAPGPGAE_00239	1.62e-231	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
HAPGPGAE_00240	3.56e-185	cobJ	2.1.1.131, 2.1.1.272	-	H	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-3B
HAPGPGAE_00241	4.24e-163	cobK	1.3.1.106, 1.3.1.54, 1.3.1.76, 4.99.1.4	-	H	ko:K02304,ko:K05895	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	reductase
HAPGPGAE_00242	7.91e-270	cbiT	2.1.1.132, 2.1.1.196	-	H	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit
HAPGPGAE_00243	6.38e-314	cbiA	6.3.5.11, 6.3.5.9	-	H	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HAPGPGAE_00244	5.27e-239	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HAPGPGAE_00245	2.81e-112	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	adenosylcobinamide kinase adenosylcobinamide-phosphate guanylyltransferase
HAPGPGAE_00246	8.01e-175	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HAPGPGAE_00247	3.85e-72	-	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
HAPGPGAE_00248	1.66e-144	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_00249	5.76e-217	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HAPGPGAE_00250	8.03e-234	cobD_2	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_00251	0.0	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HAPGPGAE_00252	1.81e-149	cobH	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_00253	5.52e-139	-	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
HAPGPGAE_00254	2.43e-108	-	-	-	S	ko:K02441	-	ko00000	Rhomboid family
HAPGPGAE_00255	3.12e-115	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00256	4.15e-298	rlmI	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HAPGPGAE_00257	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HAPGPGAE_00258	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HAPGPGAE_00259	1.93e-126	-	-	-	K	ko:K22010	-	ko00000,ko00002,ko02022	ANTAR domain protein
HAPGPGAE_00260	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HAPGPGAE_00261	0.0	-	-	-	T	-	-	-	diguanylate cyclase
HAPGPGAE_00264	5.34e-185	-	-	-	G	-	-	-	polysaccharide deacetylase
HAPGPGAE_00265	9e-192	hmrR	-	-	K	-	-	-	Transcriptional regulator
HAPGPGAE_00266	0.0	apeA	-	-	E	-	-	-	M18 family aminopeptidase
HAPGPGAE_00267	1.23e-95	-	-	GH23	M	ko:K08309	-	ko00000,ko01000,ko01011	Transglycosylase SLT domain
HAPGPGAE_00268	1.68e-131	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HAPGPGAE_00269	5.35e-246	sua	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HAPGPGAE_00270	3.52e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HAPGPGAE_00271	1.92e-38	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00272	2.11e-223	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	S1 RNA binding domain protein
HAPGPGAE_00273	2.29e-125	-	-	-	K	-	-	-	Domain of unknown function (DUF4364)
HAPGPGAE_00274	1.32e-311	spoIVA	-	-	P	ko:K06398	-	ko00000	Stage IV sporulation protein A (spore_IV_A)
HAPGPGAE_00275	0.0	aspS	6.1.1.12, 6.1.1.23	-	J	ko:K01876,ko:K09759	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HAPGPGAE_00276	3.08e-146	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HAPGPGAE_00277	1.34e-298	-	-	-	V	-	-	-	MATE efflux family protein
HAPGPGAE_00278	9.04e-99	-	-	-	P	ko:K07238	-	ko00000,ko02000	Metal cation transporter, ZIP family
HAPGPGAE_00281	6.11e-118	yvdD	3.2.2.10	-	L	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HAPGPGAE_00282	2.95e-120	chrA2	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HAPGPGAE_00283	1.92e-120	chrA1	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HAPGPGAE_00284	2.15e-181	-	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HAPGPGAE_00285	7.76e-299	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAPGPGAE_00286	2.19e-188	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_00287	3.93e-181	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component I
HAPGPGAE_00288	8.61e-251	potA	3.6.3.31	-	P	ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HAPGPGAE_00289	1.06e-211	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
HAPGPGAE_00290	0.0	-	-	-	N	ko:K01992	-	ko00000,ko00002,ko02000	transport system
HAPGPGAE_00291	2.35e-187	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HAPGPGAE_00292	4.42e-174	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
HAPGPGAE_00293	2.24e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HAPGPGAE_00295	8.25e-47	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HAPGPGAE_00297	1.32e-17	-	-	-	-	-	-	-	-
HAPGPGAE_00301	5.27e-104	-	-	-	L	-	-	-	Transposase IS116/IS110/IS902 family
HAPGPGAE_00302	8.1e-83	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HAPGPGAE_00303	2.13e-82	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HAPGPGAE_00304	4.03e-21	-	-	-	S	-	-	-	EpsG family
HAPGPGAE_00305	3.61e-64	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HAPGPGAE_00306	1.44e-54	-	-	GT2	S	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HAPGPGAE_00307	2.61e-72	-	-	-	M	-	-	-	Glycosyltransferase
HAPGPGAE_00308	7.77e-180	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.87
HAPGPGAE_00309	1.13e-39	rfaG	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HAPGPGAE_00310	2.36e-145	cpsE	-	-	M	-	-	-	sugar transferase
HAPGPGAE_00311	1.42e-08	-	-	-	-	-	-	-	-
HAPGPGAE_00313	1.51e-155	-	-	-	S	-	-	-	SprT-like family
HAPGPGAE_00315	5.12e-42	-	-	-	K	-	-	-	sequence-specific DNA binding
HAPGPGAE_00318	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
HAPGPGAE_00319	1.37e-95	-	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase SAM-like domain
HAPGPGAE_00321	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HAPGPGAE_00322	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HAPGPGAE_00323	1.88e-181	-	1.4.1.21	-	S	ko:K06989	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	homoserine dehydrogenase
HAPGPGAE_00324	4.91e-209	-	-	-	C	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase catalytic
HAPGPGAE_00325	2.56e-179	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HAPGPGAE_00326	2.28e-139	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HAPGPGAE_00327	0.0	-	4.1.1.18, 4.1.1.19	-	E	ko:K01582,ko:K01583,ko:K01585	ko00310,ko00330,ko00960,ko01100,ko01110,map00310,map00330,map00960,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Orn Lys Arg decarboxylase major
HAPGPGAE_00328	0.0	scfB	-	-	C	ko:K06871	-	ko00000	Radical SAM
HAPGPGAE_00329	3.59e-21	scfA	-	-	S	-	-	-	RSAM-modified six-cysteine peptide
HAPGPGAE_00332	0.0	ushA	3.1.3.5, 3.6.1.45	-	F	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HAPGPGAE_00333	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
HAPGPGAE_00334	7.47e-58	-	-	-	S	-	-	-	TSCPD domain
HAPGPGAE_00335	1.42e-211	-	3.1.3.97	-	S	ko:K07053	-	ko00000,ko01000	PHP domain protein
HAPGPGAE_00336	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	aconitate hydratase
HAPGPGAE_00337	0.0	-	-	-	V	-	-	-	MATE efflux family protein
HAPGPGAE_00338	2.13e-184	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HAPGPGAE_00339	8.74e-141	tcyB	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HAPGPGAE_00340	5.55e-167	fliY1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HAPGPGAE_00341	5.97e-223	-	-	-	-	-	-	-	-
HAPGPGAE_00342	0.0	cls1	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAPGPGAE_00343	2.71e-145	-	-	-	S	-	-	-	EDD domain protein, DegV family
HAPGPGAE_00344	1.75e-123	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HAPGPGAE_00345	2.35e-52	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HAPGPGAE_00346	3.82e-50	-	-	-	K	-	-	-	PFAM Phage derived protein Gp49-like (DUF891)
HAPGPGAE_00348	2.48e-111	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HAPGPGAE_00349	1.03e-138	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HAPGPGAE_00350	4.97e-70	-	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HAPGPGAE_00351	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HAPGPGAE_00352	8.74e-236	pta	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	PFAM Phosphate acetyl butaryl transferase
HAPGPGAE_00353	4.09e-136	udgA	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HAPGPGAE_00354	1.28e-254	-	-	-	LO	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00355	0.0	dinG	3.1.12.1, 3.6.4.12	-	L	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	HELICc2
HAPGPGAE_00356	1.77e-114	btuR	2.5.1.17	-	H	ko:K19221	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cob(I)yrinic acid a,c-diamide adenosyltransferase
HAPGPGAE_00357	1.78e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HAPGPGAE_00358	1.93e-125	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HAPGPGAE_00359	3.93e-133	fchA	-	-	E	-	-	-	Formiminotransferase-cyclodeaminase
HAPGPGAE_00360	3.44e-203	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HAPGPGAE_00361	8.26e-222	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Glycosyl transferase family 4
HAPGPGAE_00362	0.0	-	-	-	V	-	-	-	MATE efflux family protein
HAPGPGAE_00363	9.13e-133	ribU	-	-	S	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HAPGPGAE_00364	2e-242	-	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HAPGPGAE_00365	2.78e-273	-	-	-	G	-	-	-	Major Facilitator
HAPGPGAE_00366	0.0	-	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Beta-lactamase class C
HAPGPGAE_00367	1.25e-85	-	-	-	S	-	-	-	Bacterial PH domain
HAPGPGAE_00370	0.0	-	-	-	J	ko:K07576	-	ko00000	Metallo-beta-lactamase domain protein
HAPGPGAE_00371	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HAPGPGAE_00373	0.0	-	-	-	V	ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin transporter
HAPGPGAE_00374	5.3e-104	-	-	-	KT	-	-	-	Transcriptional regulator
HAPGPGAE_00375	8.44e-244	-	-	-	M	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	HlyD family secretion protein
HAPGPGAE_00376	0.0	-	-	-	N	-	-	-	Bacterial Ig-like domain 2
HAPGPGAE_00377	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HAPGPGAE_00378	1.17e-119	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00379	6.17e-203	-	-	-	-	-	-	-	-
HAPGPGAE_00380	1.73e-289	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HAPGPGAE_00381	1.11e-90	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	S1 RNA binding domain
HAPGPGAE_00382	4.49e-61	-	-	-	D	ko:K13052	-	ko00000,ko03036	septum formation initiator
HAPGPGAE_00383	4.58e-92	-	-	-	-	-	-	-	-
HAPGPGAE_00384	2.86e-09	yabP	-	-	S	-	-	-	Sporulation protein YabP
HAPGPGAE_00385	6.72e-47	hslR	-	-	J	-	-	-	S4 domain protein
HAPGPGAE_00386	7.71e-52	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HAPGPGAE_00387	1.43e-121	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	MazG family
HAPGPGAE_00388	7.52e-72	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_00389	9.34e-225	-	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphoribulokinase uridine kinase family
HAPGPGAE_00390	0.0	hemZ	-	-	C	-	-	-	Coproporphyrinogen dehydrogenase
HAPGPGAE_00391	2.64e-153	-	-	-	S	-	-	-	Metallo-beta-lactamase domain protein
HAPGPGAE_00392	6.41e-106	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HAPGPGAE_00393	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAPGPGAE_00394	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	exonuclease
HAPGPGAE_00395	1.01e-285	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HAPGPGAE_00396	0.0	-	-	-	S	ko:K07137	-	ko00000	FAD dependent oxidoreductase
HAPGPGAE_00397	9.56e-303	-	-	-	S	-	-	-	YbbR-like protein
HAPGPGAE_00398	1.11e-206	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HAPGPGAE_00399	4.62e-273	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HAPGPGAE_00400	0.0	pgcA	5.4.2.2, 5.4.2.8	-	G	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HAPGPGAE_00402	0.0	comM	-	-	O	ko:K07391	-	ko00000	chelatase subunit ChlI
HAPGPGAE_00403	8.93e-309	-	-	-	Q	-	-	-	Amidohydrolase family
HAPGPGAE_00404	4.49e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HAPGPGAE_00405	4.16e-200	araC_2	-	-	K	ko:K02099	-	ko00000,ko03000	transcriptional regulator AraC family
HAPGPGAE_00406	0.0	-	-	-	G	ko:K03292	-	ko00000	Transporter, major facilitator family protein
HAPGPGAE_00407	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HAPGPGAE_00408	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
HAPGPGAE_00409	1.13e-32	-	-	-	-	-	-	-	-
HAPGPGAE_00410	6.41e-205	-	-	-	P	ko:K10202	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_00411	3.55e-200	-	-	-	P	ko:K10201	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_00412	0.0	-	-	-	G	ko:K10200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Carbohydrate ABC transporter
HAPGPGAE_00413	1.25e-206	-	-	-	K	-	-	-	transcriptional regulator AraC family
HAPGPGAE_00414	3.35e-277	-	-	-	M	-	-	-	Phosphotransferase enzyme family
HAPGPGAE_00415	5.66e-168	kdpE	-	-	K	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	transcriptional regulatory protein KdpE
HAPGPGAE_00416	0.0	kdpD	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAPGPGAE_00417	2.71e-151	ktrA	-	-	C	ko:K03499	-	ko00000,ko02000	system potassium uptake protein
HAPGPGAE_00418	1.49e-307	-	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_00419	4.99e-45	-	-	-	-	-	-	-	-
HAPGPGAE_00420	9.34e-224	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00421	4.86e-129	-	-	-	S	-	-	-	Flavin reductase
HAPGPGAE_00422	3.59e-285	-	-	-	C	ko:K19955	-	ko00000,ko01000	alcohol dehydrogenase
HAPGPGAE_00423	1.92e-202	-	-	-	S	-	-	-	Aldo/keto reductase family
HAPGPGAE_00424	7.83e-288	-	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HAPGPGAE_00425	2.4e-132	-	-	-	C	-	-	-	Flavodoxin
HAPGPGAE_00426	5.52e-152	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HAPGPGAE_00427	3.45e-117	-	-	-	S	-	-	-	Prolyl oligopeptidase family
HAPGPGAE_00428	5.26e-142	-	-	-	I	-	-	-	acetylesterase activity
HAPGPGAE_00429	2.13e-277	-	-	-	I	-	-	-	Psort location Cytoplasmic, score 7.50
HAPGPGAE_00430	1.94e-244	-	-	-	C	-	-	-	Aldo/keto reductase family
HAPGPGAE_00431	8.05e-79	-	-	-	K	-	-	-	PFAM helix-turn-helix domain protein
HAPGPGAE_00433	1.32e-112	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HAPGPGAE_00434	3.46e-205	nfnA	1.18.1.2, 1.19.1.1	-	C	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	ko00000,ko00001,ko01000	domain protein
HAPGPGAE_00435	0.0	gltA	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HAPGPGAE_00436	1.92e-106	-	-	-	S	-	-	-	CBS domain
HAPGPGAE_00437	4.34e-75	-	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HAPGPGAE_00438	0.0	-	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HAPGPGAE_00439	0.0	polC	2.7.7.7	-	L	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HAPGPGAE_00440	1.49e-251	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HAPGPGAE_00441	1.56e-255	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Metalloprotease
HAPGPGAE_00442	5.41e-274	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HAPGPGAE_00443	1.44e-195	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_00444	4e-173	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HAPGPGAE_00445	1.04e-117	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HAPGPGAE_00446	6.61e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HAPGPGAE_00447	1.18e-166	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00448	4.23e-54	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
HAPGPGAE_00451	1.68e-177	spo0A	-	-	K	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HAPGPGAE_00452	8.22e-288	spoIVB	3.4.21.116	-	S	ko:K06399	-	ko00000,ko01000,ko01002	stage IV sporulation protein B
HAPGPGAE_00453	1.84e-260	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HAPGPGAE_00454	1.85e-240	-	-	-	S	-	-	-	Prokaryotic RING finger family 1
HAPGPGAE_00455	2.97e-211	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HAPGPGAE_00456	5.38e-272	napA	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_00457	4.49e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HAPGPGAE_00458	8.93e-100	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HAPGPGAE_00459	8.86e-56	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HAPGPGAE_00460	3.91e-142	-	-	-	F	-	-	-	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HAPGPGAE_00461	8.7e-233	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HAPGPGAE_00462	4.12e-310	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAPGPGAE_00463	2.31e-195	-	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HAPGPGAE_00464	4.49e-196	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_00465	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_00468	2.38e-310	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family
HAPGPGAE_00469	3.63e-214	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00470	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAPGPGAE_00471	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Melibiase
HAPGPGAE_00472	8.03e-311	lacS	-	-	G	ko:K03292,ko:K11104,ko:K16209	-	ko00000,ko02000	MFS/sugar transport protein
HAPGPGAE_00473	0.0	lacZ	3.2.1.23, 3.2.1.31	-	G	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
HAPGPGAE_00474	1.48e-123	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGPGAE_00475	3.43e-17	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
HAPGPGAE_00476	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HAPGPGAE_00477	3.16e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HAPGPGAE_00478	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding protein, transpeptidase domain protein
HAPGPGAE_00479	9.43e-280	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGPGAE_00480	6.31e-65	-	-	-	S	-	-	-	Excisionase from transposon Tn916
HAPGPGAE_00481	4.36e-186	-	-	-	L	-	-	-	Virulence-associated protein E
HAPGPGAE_00482	1.63e-71	-	-	-	L	-	-	-	Virulence-associated protein E
HAPGPGAE_00483	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_00485	3.71e-35	-	-	-	S	-	-	-	InterPro IPR004919 IPR011089
HAPGPGAE_00486	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
HAPGPGAE_00487	1.34e-242	-	-	-	L	-	-	-	restriction endonuclease
HAPGPGAE_00488	4.49e-47	-	-	-	K	-	-	-	helix-turn-helix
HAPGPGAE_00489	2.44e-129	-	-	-	-	-	-	-	-
HAPGPGAE_00490	6.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
HAPGPGAE_00491	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HAPGPGAE_00492	1.62e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HAPGPGAE_00493	1.86e-13	-	-	-	I	-	-	-	Acyltransferase
HAPGPGAE_00494	1.4e-234	-	-	-	I	-	-	-	Lipid kinase, YegS Rv2252 BmrU family
HAPGPGAE_00495	0.0	clpC	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Belongs to the ClpA ClpB family
HAPGPGAE_00496	1.23e-173	-	-	-	S	ko:K06872	-	ko00000	Pfam:TPM
HAPGPGAE_00497	4e-259	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HAPGPGAE_00498	7.27e-281	-	-	-	S	-	-	-	SPFH domain-Band 7 family
HAPGPGAE_00499	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_00500	0.0	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	K transport systems, NAD-binding component
HAPGPGAE_00501	3.95e-309	pdp	2.4.2.2, 2.4.2.4	-	F	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HAPGPGAE_00502	3.93e-292	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HAPGPGAE_00503	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
HAPGPGAE_00504	5.75e-103	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HAPGPGAE_00505	1.7e-200	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HAPGPGAE_00506	5.9e-233	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Psort location Cytoplasmic, score
HAPGPGAE_00508	3.55e-161	-	-	-	-	-	-	-	-
HAPGPGAE_00509	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HAPGPGAE_00510	6.08e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HAPGPGAE_00511	0.0	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HAPGPGAE_00512	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HAPGPGAE_00513	1.51e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HAPGPGAE_00514	2.11e-272	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HAPGPGAE_00515	0.0	yybT	-	-	T	-	-	-	domain protein
HAPGPGAE_00516	0.0	rnj	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HAPGPGAE_00517	1.7e-115	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAPGPGAE_00518	2.2e-117	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	sulfurtransferase activity
HAPGPGAE_00519	4.06e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HAPGPGAE_00520	0.0	mrdA	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding protein, transpeptidase domain protein
HAPGPGAE_00521	6.63e-122	-	-	-	S	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HAPGPGAE_00522	4.03e-162	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HAPGPGAE_00523	1.63e-235	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein, MreB Mrl family
HAPGPGAE_00524	3.13e-133	maf	-	-	D	ko:K06287	-	ko00000	Maf-like protein
HAPGPGAE_00525	6.48e-99	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HAPGPGAE_00526	0.0	ydcP	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HAPGPGAE_00527	2.63e-69	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HAPGPGAE_00528	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HAPGPGAE_00529	0.0	apu	2.4.1.25, 3.2.1.133, 3.2.1.135, 3.2.1.20, 3.2.1.54	GH13,GH31,GH77	G	ko:K00705,ko:K01187,ko:K01208	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HAPGPGAE_00530	5.69e-100	-	-	-	OU	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00531	2.22e-156	qmcA	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
HAPGPGAE_00533	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HAPGPGAE_00534	0.0	capD	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
HAPGPGAE_00535	1.37e-249	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	Stage V sporulation protein B
HAPGPGAE_00536	6.69e-201	mrp	-	-	D	-	-	-	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HAPGPGAE_00537	0.0	gdhA	1.4.1.3, 1.4.1.4	-	C	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the Glu Leu Phe Val dehydrogenases family
HAPGPGAE_00538	0.0	hcp	1.7.99.1	-	C	ko:K05601	ko00910,map00910	ko00000,ko00001,ko01000	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O
HAPGPGAE_00540	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HAPGPGAE_00541	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HAPGPGAE_00542	0.0	-	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain protein
HAPGPGAE_00543	2.33e-300	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00544	7.49e-117	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
HAPGPGAE_00545	2.02e-232	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
HAPGPGAE_00546	1.01e-170	-	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HAPGPGAE_00547	2.76e-181	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPGPGAE_00548	0.0	-	-	-	T	-	-	-	Histidine kinase
HAPGPGAE_00549	3.7e-123	-	-	-	-	-	-	-	-
HAPGPGAE_00550	0.0	-	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase
HAPGPGAE_00551	1.64e-293	uxuA	4.2.1.8	-	H	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HAPGPGAE_00553	0.0	dsdA	4.3.1.18	-	H	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HAPGPGAE_00554	3.28e-52	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HAPGPGAE_00555	4.33e-57	-	-	-	S	-	-	-	YoeB-like toxin of bacterial type II toxin-antitoxin system
HAPGPGAE_00556	1.01e-170	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HAPGPGAE_00557	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family
HAPGPGAE_00559	4.57e-90	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HAPGPGAE_00560	1.27e-315	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HAPGPGAE_00561	8.65e-53	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HAPGPGAE_00562	2.78e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HAPGPGAE_00563	3.5e-249	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HAPGPGAE_00564	0.0	ymfH	-	-	S	-	-	-	Peptidase M16 inactive domain
HAPGPGAE_00565	4.26e-268	-	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HAPGPGAE_00566	8.27e-184	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	serine-type D-Ala-D-Ala carboxypeptidase
HAPGPGAE_00567	1.24e-278	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HAPGPGAE_00568	3.74e-210	thrB	2.7.1.39	-	H	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HAPGPGAE_00569	3.14e-294	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HAPGPGAE_00570	7.82e-87	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HAPGPGAE_00571	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HAPGPGAE_00573	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Na Pi-cotransporter II-like protein
HAPGPGAE_00575	1.28e-146	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HAPGPGAE_00576	1.7e-217	-	-	-	P	ko:K03324	-	ko00000,ko02000	Na Pi-cotransporter
HAPGPGAE_00577	3.96e-72	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HAPGPGAE_00578	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC-type multidrug transport system ATPase and permease
HAPGPGAE_00579	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC-type multidrug transport system ATPase and permease
HAPGPGAE_00580	1.43e-222	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00581	0.0	-	-	-	C	-	-	-	domain protein
HAPGPGAE_00582	3.77e-217	-	-	-	S	-	-	-	ATPase family associated with various cellular activities (AAA)
HAPGPGAE_00583	0.0	-	-	-	P	-	-	-	von Willebrand factor (vWF) type A domain
HAPGPGAE_00585	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type oligopeptide transport system periplasmic component
HAPGPGAE_00586	2.35e-244	appF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HAPGPGAE_00587	1.53e-241	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HAPGPGAE_00588	3.06e-240	oppC	-	-	P	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAPGPGAE_00589	4.68e-206	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAPGPGAE_00590	1.48e-138	-	-	-	-	-	-	-	-
HAPGPGAE_00591	4.68e-183	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	capsular polysaccharide biosynthesis protein
HAPGPGAE_00592	4.04e-166	-	-	-	D	-	-	-	Capsular exopolysaccharide family
HAPGPGAE_00593	1.45e-145	-	-	-	M	-	-	-	Chain length determinant protein
HAPGPGAE_00594	7.42e-203	-	-	-	P	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HAPGPGAE_00595	1.06e-258	-	-	-	P	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HAPGPGAE_00596	0.0	-	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	transport systems ATPase components
HAPGPGAE_00597	4.81e-257	tmpC	-	-	S	ko:K07335	-	ko00000	basic membrane
HAPGPGAE_00598	5.31e-99	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HAPGPGAE_00599	6.11e-169	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	purine-nucleoside phosphorylase
HAPGPGAE_00600	2.81e-303	-	-	-	D	-	-	-	G5
HAPGPGAE_00601	4.24e-217	rluD_2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HAPGPGAE_00602	0.0	-	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HAPGPGAE_00603	9.81e-77	-	-	-	S	-	-	-	NusG domain II
HAPGPGAE_00604	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HAPGPGAE_00606	6e-105	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00607	6.54e-157	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAPGPGAE_00608	1.95e-173	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAPGPGAE_00609	1.24e-47	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	sporulation transcriptional regulator SpoIIID
HAPGPGAE_00610	2.67e-131	-	-	-	S	ko:K16789	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HAPGPGAE_00612	5.93e-304	nspC	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	carboxynorspermidine decarboxylase
HAPGPGAE_00613	9.23e-307	LYS1	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase
HAPGPGAE_00614	1.13e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HAPGPGAE_00615	8.23e-215	speE	2.5.1.16	-	H	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HAPGPGAE_00616	0.0	speA	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Orn Lys Arg decarboxylase major
HAPGPGAE_00617	1.65e-173	-	-	-	T	-	-	-	response regulator
HAPGPGAE_00618	1.67e-209	-	-	-	T	-	-	-	GHKL domain
HAPGPGAE_00620	3.26e-106	-	-	-	G	-	-	-	Domain of unknown function (DUF386)
HAPGPGAE_00621	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00622	1.03e-66	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
HAPGPGAE_00623	6.63e-63	-	-	-	L	-	-	-	RelB antitoxin
HAPGPGAE_00625	6.36e-153	-	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma-70 region 2
HAPGPGAE_00626	3.26e-64	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAPGPGAE_00627	1.27e-75	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAPGPGAE_00628	1.37e-261	-	-	-	D	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00629	1.04e-32	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00630	1.68e-50	-	-	-	-	-	-	-	-
HAPGPGAE_00632	1.63e-300	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HAPGPGAE_00633	1.55e-292	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HAPGPGAE_00634	1.68e-233	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HAPGPGAE_00636	7.02e-30	-	-	-	S	-	-	-	ABC-2 family transporter protein
HAPGPGAE_00637	1.39e-195	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HAPGPGAE_00638	8.2e-81	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HAPGPGAE_00639	1.14e-297	dapL	2.6.1.83	-	H	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate
HAPGPGAE_00640	1.59e-209	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HAPGPGAE_00641	6.35e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAPGPGAE_00642	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
HAPGPGAE_00643	1.33e-224	-	-	-	G	-	-	-	Aldose 1-epimerase
HAPGPGAE_00644	1.41e-264	-	-	-	T	-	-	-	Histidine kinase
HAPGPGAE_00645	5.43e-156	-	-	-	T	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAPGPGAE_00646	3.46e-25	-	-	-	-	-	-	-	-
HAPGPGAE_00647	5.81e-195	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00648	3.48e-190	-	-	-	CO	ko:K06196	-	ko00000,ko02000	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HAPGPGAE_00649	0.0	-	-	-	M	-	-	-	peptidoglycan binding domain protein
HAPGPGAE_00650	3.86e-172	-	-	-	M	-	-	-	peptidoglycan binding domain protein
HAPGPGAE_00651	3.37e-115	-	-	-	C	-	-	-	Flavodoxin domain
HAPGPGAE_00652	6.12e-230	-	1.1.1.29, 1.1.1.399, 1.1.1.95	-	CH	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
HAPGPGAE_00654	1.76e-173	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HAPGPGAE_00655	2.73e-86	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HAPGPGAE_00656	1.21e-205	-	-	-	T	-	-	-	cheY-homologous receiver domain
HAPGPGAE_00657	8.84e-43	-	-	-	S	-	-	-	Protein conserved in bacteria
HAPGPGAE_00658	5.06e-237	-	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
HAPGPGAE_00659	3.14e-276	-	2.7.1.165	-	G	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	MOFRL family
HAPGPGAE_00661	2.28e-292	-	-	-	M	-	-	-	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HAPGPGAE_00663	4.15e-72	-	-	-	S	-	-	-	No similarity found
HAPGPGAE_00664	5.59e-73	-	-	-	S	-	-	-	SGNH hydrolase-like domain, acetyltransferase AlgX
HAPGPGAE_00665	0.0	-	-	-	M	ko:K19294	-	ko00000	Psort location CytoplasmicMembrane, score
HAPGPGAE_00667	2.68e-09	-	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HAPGPGAE_00668	5.86e-116	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	to two-component sensor histidine kinase YesN
HAPGPGAE_00669	1.33e-252	-	-	-	S	-	-	-	Glycosyl hydrolase family 115
HAPGPGAE_00670	5.51e-126	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
HAPGPGAE_00671	3.11e-140	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPGPGAE_00672	2.41e-170	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAPGPGAE_00673	9.97e-96	-	-	-	KT	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Psort location Cytoplasmic, score 9.98
HAPGPGAE_00674	5.18e-57	-	-	-	M	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HAPGPGAE_00675	7.38e-214	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HAPGPGAE_00676	2.94e-47	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00677	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HAPGPGAE_00678	8.43e-317	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00679	9.37e-159	metH2	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Vitamin B12 dependent methionine synthase activation
HAPGPGAE_00680	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_00681	2.65e-15	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	K02342 DNA polymerase III subunit epsilon
HAPGPGAE_00682	9.07e-143	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
HAPGPGAE_00683	3.55e-154	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
HAPGPGAE_00684	1.29e-238	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CRISPR system CASCADE complex protein CasC
HAPGPGAE_00685	1.46e-145	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
HAPGPGAE_00686	0.0	casA	-	-	L	ko:K19123	-	ko00000,ko02048	CRISPR system CASCADE complex protein CasA
HAPGPGAE_00687	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase, Cas3
HAPGPGAE_00688	7.67e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPGPGAE_00690	0.0	-	-	-	S	-	-	-	Domain of unknown function DUF87
HAPGPGAE_00691	1.25e-179	-	-	-	L	ko:K07126	-	ko00000	Sel1-like repeats.
HAPGPGAE_00692	2.37e-114	-	-	-	K	-	-	-	WYL domain
HAPGPGAE_00694	3.56e-233	-	-	-	-	-	-	-	-
HAPGPGAE_00695	0.0	-	-	-	S	-	-	-	COG0433 Predicted ATPase
HAPGPGAE_00696	1.75e-229	-	-	-	-	-	-	-	-
HAPGPGAE_00697	8.59e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF4869)
HAPGPGAE_00698	5.25e-298	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00699	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00700	1.57e-150	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
HAPGPGAE_00701	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00702	7.5e-202	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00703	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HAPGPGAE_00704	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HAPGPGAE_00705	3.56e-195	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HAPGPGAE_00707	3.71e-169	-	-	-	S	-	-	-	RloB-like protein
HAPGPGAE_00708	5.84e-294	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
HAPGPGAE_00709	4.76e-160	ddpX	3.4.13.22	-	-	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-
HAPGPGAE_00711	3.96e-310	-	-	-	S	-	-	-	Double zinc ribbon
HAPGPGAE_00712	7.99e-75	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAPGPGAE_00714	2.22e-163	-	-	-	L	-	-	-	Resolvase, N terminal domain
HAPGPGAE_00715	4.66e-88	-	-	-	-	-	-	-	-
HAPGPGAE_00716	9.08e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF1071)
HAPGPGAE_00717	1.74e-224	-	-	-	L	-	-	-	YqaJ viral recombinase family
HAPGPGAE_00719	1.68e-227	-	-	-	S	-	-	-	Domain of unknown function (DUF932)
HAPGPGAE_00721	0.0	-	-	-	L	-	-	-	Resolvase, N terminal domain
HAPGPGAE_00723	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase P4 family
HAPGPGAE_00726	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
HAPGPGAE_00727	7.69e-142	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HAPGPGAE_00729	5.17e-140	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HAPGPGAE_00730	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HAPGPGAE_00731	5.91e-229	-	-	-	-	-	-	-	-
HAPGPGAE_00732	0.0	-	-	-	S	-	-	-	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HAPGPGAE_00733	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HAPGPGAE_00734	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_00735	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HAPGPGAE_00736	8.99e-114	-	-	-	K	-	-	-	MarR family
HAPGPGAE_00737	1.94e-215	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HAPGPGAE_00738	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HAPGPGAE_00739	3.73e-237	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HAPGPGAE_00740	7.17e-109	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HAPGPGAE_00741	5.96e-304	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HAPGPGAE_00742	2.55e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HAPGPGAE_00743	1.08e-218	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
HAPGPGAE_00744	7.06e-249	-	-	-	S	-	-	-	Nitronate monooxygenase
HAPGPGAE_00745	1.25e-213	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Psort location Cytoplasmic, score
HAPGPGAE_00746	3.57e-211	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAPGPGAE_00747	5.43e-228	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HAPGPGAE_00748	9.52e-205	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HAPGPGAE_00749	3.48e-44	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAPGPGAE_00750	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HAPGPGAE_00751	8.2e-315	-	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
HAPGPGAE_00752	2.73e-263	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HAPGPGAE_00753	9.47e-284	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_00754	1.57e-97	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HAPGPGAE_00755	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HAPGPGAE_00756	0.0	spoVD	3.4.16.4	-	M	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein
HAPGPGAE_00757	4.43e-100	-	-	-	-	-	-	-	-
HAPGPGAE_00758	3.82e-229	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HAPGPGAE_00759	3.36e-46	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HAPGPGAE_00760	2.81e-75	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00761	1.59e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HAPGPGAE_00762	2.25e-150	-	-	-	C	-	-	-	NADPH-dependent FMN reductase
HAPGPGAE_00763	0.0	lacZ	3.2.1.23, 3.2.1.31	-	G	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
HAPGPGAE_00764	8.61e-89	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HAPGPGAE_00765	4.76e-212	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00766	4.76e-159	-	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	Psort location Cytoplasmic, score
HAPGPGAE_00767	1.07e-60	-	-	-	-	-	-	-	-
HAPGPGAE_00768	6.38e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGPGAE_00769	3.65e-149	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_00770	1.19e-154	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_00771	4.72e-160	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00772	6.98e-211	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00773	1.63e-234	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase
HAPGPGAE_00774	7.93e-248	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Kinase, PfkB family
HAPGPGAE_00775	1.6e-215	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HAPGPGAE_00776	1.75e-186	-	1.1.1.69	-	IQ	ko:K00046	-	ko00000,ko01000	PFAM Short-chain dehydrogenase reductase SDR
HAPGPGAE_00777	5.64e-296	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00778	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HAPGPGAE_00779	1.54e-87	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HAPGPGAE_00780	2.91e-99	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HAPGPGAE_00782	4.61e-188	ttcA2	-	-	H	-	-	-	Belongs to the TtcA family
HAPGPGAE_00783	9.33e-295	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HAPGPGAE_00784	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HAPGPGAE_00785	7.19e-235	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HAPGPGAE_00786	1.16e-302	-	-	-	-	-	-	-	-
HAPGPGAE_00787	0.0	-	-	-	M	-	-	-	Diguanylate cyclase, GGDEF domain
HAPGPGAE_00788	2.58e-296	-	-	-	V	-	-	-	Glycosyl transferase, family 2
HAPGPGAE_00789	1.28e-92	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HAPGPGAE_00790	0.0	-	-	-	S	-	-	-	O-Antigen ligase
HAPGPGAE_00791	4.09e-249	-	-	GT2	M	ko:K19427	-	ko00000,ko01000	Glycosyltransferase group 2 family protein
HAPGPGAE_00792	1.42e-70	-	-	-	K	-	-	-	Probable zinc-ribbon domain
HAPGPGAE_00793	7.34e-291	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HAPGPGAE_00794	6.09e-275	-	-	-	S	-	-	-	Belongs to the UPF0348 family
HAPGPGAE_00795	0.0	-	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HAPGPGAE_00796	0.0	glpK	2.7.1.30	-	H	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HAPGPGAE_00797	1.9e-26	-	-	-	D	-	-	-	Plasmid stabilization system
HAPGPGAE_00798	8.74e-62	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HAPGPGAE_00800	1.25e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGPGAE_00801	0.0	-	-	-	S	ko:K07003	-	ko00000	Psort location CytoplasmicMembrane, score
HAPGPGAE_00802	0.0	-	-	-	S	ko:K01421	-	ko00000	Psort location Cellwall, score
HAPGPGAE_00803	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HAPGPGAE_00804	1.63e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HAPGPGAE_00805	2.26e-213	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HAPGPGAE_00806	1.3e-239	-	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase NAD-binding domain protein
HAPGPGAE_00807	2.06e-129	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00808	6.31e-51	-	-	-	S	-	-	-	SPP1 phage holin
HAPGPGAE_00809	1.29e-31	-	-	-	-	-	-	-	-
HAPGPGAE_00810	4.35e-94	-	3.4.17.14	-	M	ko:K08640	-	ko00000,ko01000,ko01002,ko01011	Peptidase M15A
HAPGPGAE_00812	3.58e-243	-	-	-	N	-	-	-	Bacterial Ig-like domain (group 2)
HAPGPGAE_00813	3.29e-33	-	-	-	-	-	-	-	-
HAPGPGAE_00814	0.0	-	-	-	N	-	-	-	domain, Protein
HAPGPGAE_00815	1.5e-202	yabE	-	-	S	-	-	-	G5 domain
HAPGPGAE_00816	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HAPGPGAE_00817	1.19e-259	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HAPGPGAE_00818	1.54e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
HAPGPGAE_00819	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HAPGPGAE_00820	2.35e-47	-	-	-	S	-	-	-	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
HAPGPGAE_00821	1.03e-111	-	-	-	-	-	-	-	-
HAPGPGAE_00822	1.63e-177	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HAPGPGAE_00823	2.72e-56	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAPGPGAE_00824	1.75e-99	-	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HAPGPGAE_00825	1.28e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAPGPGAE_00826	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HAPGPGAE_00827	1.13e-190	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HAPGPGAE_00828	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HAPGPGAE_00829	1.54e-87	-	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HAPGPGAE_00830	3.29e-93	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HAPGPGAE_00831	1.13e-43	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HAPGPGAE_00832	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAPGPGAE_00833	7.95e-98	-	-	-	M	-	-	-	glycosyl transferase group 1
HAPGPGAE_00834	3.81e-151	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Belongs to the sigma-70 factor family
HAPGPGAE_00835	9.26e-98	spoIIAB	2.7.11.1	-	T	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HAPGPGAE_00836	6.43e-66	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HAPGPGAE_00837	7.33e-289	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydrofolate synthase activity
HAPGPGAE_00838	6.75e-66	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00839	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HAPGPGAE_00840	1.04e-250	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HAPGPGAE_00841	0.0	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00842	7.27e-78	epsJ2	-	-	S	-	-	-	Psort location Cytoplasmic, score 9.97
HAPGPGAE_00843	0.0	-	1.5.1.20, 2.1.1.10	-	H	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	homocysteine S-methyltransferase
HAPGPGAE_00844	3.22e-157	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HAPGPGAE_00845	1.3e-282	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HAPGPGAE_00846	1.32e-97	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator, AsnC family
HAPGPGAE_00847	5.17e-123	-	-	-	S	-	-	-	Domain of unknown function (DUF4358)
HAPGPGAE_00848	2.56e-249	-	-	-	M	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HAPGPGAE_00849	4.34e-189	-	-	-	-	-	-	-	-
HAPGPGAE_00850	2.64e-79	-	-	-	P	-	-	-	Belongs to the ArsC family
HAPGPGAE_00851	7.31e-38	-	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
HAPGPGAE_00852	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAPGPGAE_00853	5.48e-236	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HAPGPGAE_00854	3.16e-178	-	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Nitroreductase family
HAPGPGAE_00855	6.09e-199	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HAPGPGAE_00856	0.0	tetP	-	-	J	-	-	-	elongation factor G
HAPGPGAE_00857	5.44e-225	-	-	-	O	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00858	0.0	-	-	-	I	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00859	0.0	hgdC2	-	-	I	-	-	-	CoA-substrate-specific enzyme activase
HAPGPGAE_00860	2.22e-185	-	-	-	S	-	-	-	TraX protein
HAPGPGAE_00862	1.56e-144	-	-	-	-	-	-	-	-
HAPGPGAE_00864	8.64e-225	-	-	-	K	-	-	-	AraC-like ligand binding domain
HAPGPGAE_00865	4.02e-196	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
HAPGPGAE_00866	5.88e-164	-	-	-	K	ko:K22293	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
HAPGPGAE_00868	1.18e-46	-	-	-	S	-	-	-	Putative cell wall binding repeat
HAPGPGAE_00870	4.76e-70	-	-	-	-	-	-	-	-
HAPGPGAE_00871	3.6e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
HAPGPGAE_00872	0.0	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HAPGPGAE_00873	0.0	-	-	-	M	-	-	-	Gram-positive pilin backbone subunit 2, Cna-B-like domain
HAPGPGAE_00874	1.56e-192	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HAPGPGAE_00875	2.27e-143	-	-	-	S	-	-	-	domain, Protein
HAPGPGAE_00876	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HAPGPGAE_00877	1.05e-49	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HAPGPGAE_00878	1.38e-189	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
HAPGPGAE_00879	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HAPGPGAE_00880	3.85e-301	-	-	-	E	-	-	-	Peptidase dimerisation domain
HAPGPGAE_00881	1.86e-122	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Glycerol-3-phosphate responsive antiterminator
HAPGPGAE_00882	0.0	glpA	1.1.5.3	-	C	ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HAPGPGAE_00883	5.47e-298	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00884	2.72e-82	-	-	-	S	-	-	-	protein with conserved CXXC pairs
HAPGPGAE_00885	4.06e-245	modC	3.6.3.29	-	E	ko:K02017	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HAPGPGAE_00886	4.29e-152	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Molybdate ABC transporter
HAPGPGAE_00887	2.19e-178	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, periplasmic molybdate-binding protein
HAPGPGAE_00888	2.89e-223	mog	-	-	H	-	-	-	Molybdenum cofactor synthesis domain protein
HAPGPGAE_00889	1.98e-233	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HAPGPGAE_00890	4.94e-109	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HAPGPGAE_00891	1.81e-252	moeA2	-	-	H	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00892	6.06e-102	mobB	2.7.7.77	-	H	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Molybdopterin-guanine dinucleotide biosynthesis protein
HAPGPGAE_00893	3.33e-285	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA C-terminal region (domain IV)
HAPGPGAE_00894	1.37e-198	-	-	-	-	-	-	-	-
HAPGPGAE_00895	0.0	-	1.2.7.5	-	C	ko:K03738,ko:K19515	ko00030,ko00362,ko01100,ko01120,ko01200,map00030,map00362,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Aldehyde ferredoxin oxidoreductase, N-terminal domain
HAPGPGAE_00896	4.48e-145	-	-	-	C	-	-	-	4Fe-4S binding domain
HAPGPGAE_00898	1.23e-181	fdhD	-	-	C	ko:K02379	-	ko00000	FdhD/NarQ family
HAPGPGAE_00899	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HAPGPGAE_00900	0.0	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HAPGPGAE_00901	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00902	0.0	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system
HAPGPGAE_00903	8.43e-207	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HAPGPGAE_00904	6.26e-168	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	COG COG1349 Transcriptional regulators of sugar metabolism
HAPGPGAE_00905	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HAPGPGAE_00906	2.7e-221	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	Menaquinone biosynthesis
HAPGPGAE_00907	3.64e-150	-	-	-	K	-	-	-	Cyclic nucleotide-monophosphate binding domain
HAPGPGAE_00908	3.17e-235	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
HAPGPGAE_00909	1.37e-141	-	-	-	S	-	-	-	Flavin reductase-like protein
HAPGPGAE_00910	7.7e-111	queT	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00911	8.12e-158	-	-	-	S	-	-	-	HAD-hyrolase-like
HAPGPGAE_00914	3.57e-260	pfkA	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HAPGPGAE_00915	4.69e-302	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HAPGPGAE_00916	0.0	-	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_00918	3.83e-64	-	-	-	-	-	-	-	-
HAPGPGAE_00920	3.61e-208	-	-	-	S	-	-	-	Replication initiator protein A domain protein
HAPGPGAE_00921	4.89e-184	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HAPGPGAE_00922	1.35e-203	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HAPGPGAE_00925	2.64e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF3846)
HAPGPGAE_00926	1.84e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
HAPGPGAE_00927	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_00928	8.58e-54	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_00930	0.0	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
HAPGPGAE_00931	3.47e-33	-	-	-	-	-	-	-	-
HAPGPGAE_00932	9.19e-266	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGPGAE_00933	0.0	-	-	-	L	-	-	-	domain protein
HAPGPGAE_00934	3.15e-175	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HAPGPGAE_00937	9.92e-76	-	-	-	-	-	-	-	-
HAPGPGAE_00938	5.27e-188	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HAPGPGAE_00939	4.84e-256	-	-	-	M	-	-	-	Glycosyl transferases group 1
HAPGPGAE_00940	1.73e-247	-	-	-	S	-	-	-	EpsG family
HAPGPGAE_00941	1.58e-240	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HAPGPGAE_00942	2.29e-76	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
HAPGPGAE_00943	3.35e-268	-	-	-	M	-	-	-	Polysaccharide pyruvyl transferase
HAPGPGAE_00944	4.04e-241	-	-	-	M	-	-	-	Glycosyl transferases group 1
HAPGPGAE_00945	3.29e-123	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HAPGPGAE_00946	6.53e-06	-	-	-	I	-	-	-	Acyltransferase family
HAPGPGAE_00947	7.48e-239	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HAPGPGAE_00948	5.6e-258	-	-	-	C	-	-	-	PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit
HAPGPGAE_00949	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAPGPGAE_00951	2.2e-197	-	-	-	L	-	-	-	single-stranded DNA binding
HAPGPGAE_00952	0.000648	-	-	-	-	-	-	-	-
HAPGPGAE_00953	4.39e-117	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HAPGPGAE_00955	9.79e-161	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HAPGPGAE_00956	7.65e-19	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HAPGPGAE_00957	1.94e-88	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HAPGPGAE_00959	1e-131	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HAPGPGAE_00960	3.86e-196	-	-	-	K	-	-	-	DNA binding
HAPGPGAE_00962	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_00964	1.33e-190	-	-	-	J	-	-	-	SpoU rRNA Methylase family
HAPGPGAE_00965	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_00968	3.35e-09	-	-	-	T	-	-	-	Histidine kinase
HAPGPGAE_00969	9.39e-196	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HAPGPGAE_00970	2.42e-194	-	-	-	S	-	-	-	HAD hydrolase, family IIB
HAPGPGAE_00971	7.81e-89	-	-	-	S	-	-	-	YjbR
HAPGPGAE_00972	1.41e-75	-	-	-	-	-	-	-	-
HAPGPGAE_00973	1.48e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF2500)
HAPGPGAE_00974	3.17e-111	hsp18	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HAPGPGAE_00975	7.72e-156	-	-	-	K	-	-	-	FCD
HAPGPGAE_00976	0.0	NPD5_3681	-	-	E	-	-	-	amino acid
HAPGPGAE_00977	0.0	apeB	3.4.11.21	-	E	ko:K01267	-	ko00000,ko01000,ko01002,ko04131	M18 family aminopeptidase
HAPGPGAE_00978	1.9e-104	-	-	-	F	-	-	-	Belongs to the 5'-nucleotidase family
HAPGPGAE_00979	0.0	-	-	-	T	-	-	-	Response regulator receiver domain protein
HAPGPGAE_00980	0.0	-	-	-	FG	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAPGPGAE_00981	2.25e-245	-	-	-	S	-	-	-	AI-2E family transporter
HAPGPGAE_00982	4.77e-305	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_00983	3.24e-249	dmpA	3.4.11.19	-	EQ	ko:K01266	-	ko00000,ko01000,ko01002	Peptidase family S58
HAPGPGAE_00984	0.0	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HAPGPGAE_00985	8.44e-176	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HAPGPGAE_00986	1.07e-242	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HAPGPGAE_00987	2.41e-259	-	-	-	S	-	-	-	Acyltransferase family
HAPGPGAE_00988	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HAPGPGAE_00989	1.72e-105	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HAPGPGAE_00994	8.63e-154	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HAPGPGAE_00995	3.78e-271	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HAPGPGAE_00999	9.8e-167	-	-	-	T	-	-	-	response regulator receiver
HAPGPGAE_01000	0.0	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HAPGPGAE_01001	8.39e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HAPGPGAE_01002	2.96e-242	-	-	-	C	ko:K03614	-	ko00000	Belongs to the NqrB RnfD family
HAPGPGAE_01003	2.56e-162	-	-	-	C	ko:K03613	-	ko00000	Psort location CytoplasmicMembrane, score
HAPGPGAE_01004	2.59e-102	-	-	-	C	ko:K03617	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_01005	3.15e-226	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
HAPGPGAE_01006	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
HAPGPGAE_01007	0.0	rhlE	3.6.4.13	-	L	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Belongs to the DEAD box helicase family
HAPGPGAE_01008	2.01e-209	rlmA	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase
HAPGPGAE_01009	4.79e-294	-	-	-	I	-	-	-	Psort location Cytoplasmic, score 7.50
HAPGPGAE_01010	1.38e-315	-	-	-	V	-	-	-	MATE efflux family protein
HAPGPGAE_01011	0.0	-	-	-	E	ko:K03310	-	ko00000	amino acid carrier protein
HAPGPGAE_01013	1.37e-115	-	-	-	-	-	-	-	-
HAPGPGAE_01014	0.0	-	-	-	K	ko:K00375	-	ko00000,ko03000	Transcriptional regulator, GntR family
HAPGPGAE_01015	5.13e-141	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01016	4.04e-255	-	-	-	S	ko:K07007	-	ko00000	Flavoprotein family
HAPGPGAE_01017	1.33e-118	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein T
HAPGPGAE_01019	1.37e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HAPGPGAE_01020	3.18e-118	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HAPGPGAE_01021	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HAPGPGAE_01022	2.79e-275	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HAPGPGAE_01025	9.9e-285	-	-	-	S	-	-	-	SGNH hydrolase-like domain, acetyltransferase AlgX
HAPGPGAE_01026	0.0	-	-	-	M	ko:K19294	-	ko00000	Psort location CytoplasmicMembrane, score
HAPGPGAE_01027	6.97e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4358)
HAPGPGAE_01028	5.53e-177	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Serine-type D-Ala-D-Ala carboxypeptidase
HAPGPGAE_01029	8.17e-98	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HAPGPGAE_01030	9.02e-232	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HAPGPGAE_01031	4.84e-73	spoVAE	-	-	S	ko:K06407	-	ko00000	Stage V sporulation protein AE
HAPGPGAE_01033	4.57e-45	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HAPGPGAE_01034	2.77e-176	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HAPGPGAE_01035	5.29e-245	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HAPGPGAE_01036	9.12e-119	-	-	-	-	-	-	-	-
HAPGPGAE_01037	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA synthetase
HAPGPGAE_01038	4.72e-211	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Psort location Cytoplasmic, score
HAPGPGAE_01039	3.6e-30	-	-	-	-	-	-	-	-
HAPGPGAE_01040	3.26e-312	-	-	-	M	-	-	-	Peptidase, M23 family
HAPGPGAE_01041	5.06e-152	-	-	-	S	-	-	-	Putative zinc-finger
HAPGPGAE_01042	4.87e-113	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
HAPGPGAE_01043	0.0	ptsP	2.7.3.9, 2.7.9.2	-	G	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAPGPGAE_01044	1.21e-53	-	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier, HPr family
HAPGPGAE_01045	2.26e-135	-	-	-	S	-	-	-	Domain of unknown function (DUF4830)
HAPGPGAE_01046	1.25e-283	-	-	-	M	-	-	-	hydrolase, family 25
HAPGPGAE_01047	1.76e-236	-	-	-	S	ko:K07035	-	ko00000	Psort location CytoplasmicMembrane, score
HAPGPGAE_01048	9.85e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HAPGPGAE_01049	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HAPGPGAE_01050	1.17e-219	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HAPGPGAE_01051	1.57e-295	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HAPGPGAE_01052	9.07e-198	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HAPGPGAE_01053	5.4e-294	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HAPGPGAE_01054	9.25e-217	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HAPGPGAE_01057	8.43e-313	rhaA	5.3.1.14	-	G	ko:K01813	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
HAPGPGAE_01058	3.34e-209	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HAPGPGAE_01059	3.91e-57	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
HAPGPGAE_01060	1.41e-22	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HAPGPGAE_01061	1.56e-88	-	-	-	K	-	-	-	AraC-like ligand binding domain
HAPGPGAE_01062	1.64e-233	-	-	-	S	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HAPGPGAE_01063	2.7e-185	-	-	-	S	-	-	-	Cupin domain
HAPGPGAE_01064	1.62e-121	-	-	-	S	-	-	-	Flavin reductase
HAPGPGAE_01065	1.1e-81	-	-	-	K	-	-	-	Transcriptional regulator
HAPGPGAE_01066	3.09e-51	-	-	-	-	-	-	-	-
HAPGPGAE_01068	1.09e-249	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HAPGPGAE_01069	1.36e-243	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HAPGPGAE_01070	2.36e-268	-	-	-	S	-	-	-	domain protein
HAPGPGAE_01071	5.37e-220	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01072	0.0	-	-	-	T	-	-	-	Diguanylate cyclase (GGDEF) domain protein
HAPGPGAE_01073	1.57e-107	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01074	1.15e-115	niaR	-	-	S	ko:K07105	-	ko00000	3H domain
HAPGPGAE_01075	0.0	-	3.2.1.133, 3.2.1.135, 3.2.1.54, 3.5.4.33	GH13	G	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko03016	Alpha amylase, catalytic domain protein
HAPGPGAE_01076	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HAPGPGAE_01077	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_01078	1.7e-213	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HAPGPGAE_01079	2.33e-284	-	-	-	C	-	-	-	4Fe-4S dicluster domain
HAPGPGAE_01080	0.0	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HAPGPGAE_01081	6.02e-224	envE	3.1.4.46, 3.2.1.18, 3.2.1.8	GH33	E	ko:K01126,ko:K01181,ko:K01186	ko00511,ko00564,ko00600,ko04142,map00511,map00564,map00600,map04142	ko00000,ko00001,ko01000,ko02042	lipolytic protein G-D-S-L family
HAPGPGAE_01082	3.11e-44	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
HAPGPGAE_01083	1.43e-81	-	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
HAPGPGAE_01084	3.39e-17	-	-	-	-	-	-	-	-
HAPGPGAE_01085	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HAPGPGAE_01086	2.13e-44	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	Fe2 transport system protein A
HAPGPGAE_01087	2.81e-36	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	Fe2 transport system protein A
HAPGPGAE_01088	1.42e-143	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01089	5.12e-139	-	-	-	F	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01090	1.31e-273	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HAPGPGAE_01092	2.06e-234	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HAPGPGAE_01093	6.52e-217	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HAPGPGAE_01094	7.79e-193	-	-	GT2,GT4	M	ko:K07011,ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 21
HAPGPGAE_01095	0.0	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase, group 2 family protein
HAPGPGAE_01096	7.87e-209	-	-	-	D	ko:K06381	-	ko00000	sporulation resulting in formation of a cellular spore
HAPGPGAE_01098	1.25e-146	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGPGAE_01099	4.45e-135	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HAPGPGAE_01101	7.67e-95	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HAPGPGAE_01103	2.87e-117	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HAPGPGAE_01104	5.04e-94	-	-	-	-	-	-	-	-
HAPGPGAE_01107	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAPGPGAE_01108	1.76e-178	cps4J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HAPGPGAE_01109	4.74e-271	-	1.1.1.22	-	C	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
HAPGPGAE_01110	3.67e-254	lspL	5.1.3.6	-	M	ko:K08679	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	epimerase dehydratase
HAPGPGAE_01111	6.05e-293	wecB	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
HAPGPGAE_01112	1.32e-293	-	1.1.1.367	-	GM	ko:K19068	-	ko00000,ko01000	NAD dependent epimerase/dehydratase family
HAPGPGAE_01113	3.16e-70	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
HAPGPGAE_01114	8.85e-244	capD	5.1.3.2	-	M	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Polysaccharide biosynthesis protein
HAPGPGAE_01116	2.92e-105	-	-	-	S	-	-	-	Glycosyl transferase, family 2
HAPGPGAE_01117	1.11e-30	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HAPGPGAE_01118	7.72e-96	-	-	-	M	-	-	-	Glycosyl transferases group 1
HAPGPGAE_01119	2.99e-21	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HAPGPGAE_01120	1.46e-218	-	-	GT4	M	ko:K13004	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase 4-like
HAPGPGAE_01121	6.96e-157	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HAPGPGAE_01122	1.74e-107	-	-	-	L	-	-	-	domain protein
HAPGPGAE_01123	3.09e-71	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HAPGPGAE_01124	7.59e-124	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01125	3.26e-68	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HAPGPGAE_01126	1.71e-300	-	-	-	EG	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	ko00000,ko02000	Gluconate
HAPGPGAE_01127	0.0	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HAPGPGAE_01128	1.9e-170	-	-	-	K	ko:K05799	-	ko00000,ko03000	Transcriptional regulator, GntR family
HAPGPGAE_01129	6.49e-147	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HAPGPGAE_01130	7.81e-209	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HAPGPGAE_01131	6.62e-177	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HAPGPGAE_01132	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAPGPGAE_01133	8.31e-274	-	-	-	S	ko:K07001	-	ko00000	Psort location Cytoplasmic, score 8.96
HAPGPGAE_01134	9.87e-159	-	-	-	S	-	-	-	IA, variant 3
HAPGPGAE_01135	5.94e-238	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HAPGPGAE_01136	4.63e-123	rcoM2	-	-	KT	ko:K02477,ko:K21696	-	ko00000,ko02022,ko03000	phosphorelay signal transduction system
HAPGPGAE_01137	0.0	pepQ	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HAPGPGAE_01138	4.82e-205	cobW	-	-	S	-	-	-	CobW/HypB/UreG, nucleotide-binding domain
HAPGPGAE_01139	1.03e-237	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01140	5.31e-54	-	-	-	-	-	-	-	-
HAPGPGAE_01141	0.0	-	-	-	O	-	-	-	ATPase, AAA family
HAPGPGAE_01142	5.69e-234	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01143	6.99e-208	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HAPGPGAE_01144	1.34e-297	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HAPGPGAE_01145	1.65e-243	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	synthase
HAPGPGAE_01146	6.66e-113	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HAPGPGAE_01147	2.7e-295	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HAPGPGAE_01148	3.45e-264	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HAPGPGAE_01149	8.91e-248	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HAPGPGAE_01150	1.65e-243	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HAPGPGAE_01152	9.44e-183	-	-	-	-	-	-	-	-
HAPGPGAE_01153	1.49e-166	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HAPGPGAE_01154	2.51e-197	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01155	0.0	-	-	-	-	-	-	-	-
HAPGPGAE_01156	3.33e-140	-	-	-	F	-	-	-	Cytidylate kinase-like family
HAPGPGAE_01157	3.06e-288	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01158	2.24e-148	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HAPGPGAE_01159	0.0	-	-	-	S	ko:K07137	-	ko00000	Oxidoreductase
HAPGPGAE_01160	3.27e-115	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAPGPGAE_01161	2.8e-57	spiA	-	-	K	ko:K18831	-	ko00000,ko02048,ko03000	sequence-specific DNA binding
HAPGPGAE_01162	2.25e-186	-	-	-	-	-	-	-	-
HAPGPGAE_01163	1.99e-194	-	-	-	L	-	-	-	DNA metabolism protein
HAPGPGAE_01164	0.0	-	-	-	L	-	-	-	DNA modification repair radical SAM protein
HAPGPGAE_01165	1.52e-150	-	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	DNA-binding helix-turn-helix protein
HAPGPGAE_01168	4.31e-178	-	-	-	S	-	-	-	TraX protein
HAPGPGAE_01169	1.12e-212	-	-	-	K	-	-	-	LysR substrate binding domain protein
HAPGPGAE_01170	0.0	-	-	-	I	-	-	-	Lipase (class 3)
HAPGPGAE_01171	4.01e-91	-	-	-	S	ko:K06934	-	ko00000	Domain of unknown function (DUF296)
HAPGPGAE_01172	1.3e-36	-	-	-	-	-	-	-	-
HAPGPGAE_01173	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01174	1.18e-103	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HAPGPGAE_01176	1.46e-117	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HAPGPGAE_01177	5.88e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HAPGPGAE_01178	3.64e-249	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HAPGPGAE_01179	5.86e-227	rlmL_1	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HAPGPGAE_01180	1.02e-196	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HAPGPGAE_01181	4.58e-217	cbiO	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HAPGPGAE_01182	2.12e-185	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HAPGPGAE_01183	1.29e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HAPGPGAE_01184	2.49e-277	-	-	-	-	-	-	-	-
HAPGPGAE_01185	4.89e-130	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_01187	1.72e-190	-	-	-	-	-	-	-	-
HAPGPGAE_01189	1.17e-248	lldD	-	-	C	-	-	-	FMN-dependent dehydrogenase
HAPGPGAE_01190	1.36e-215	rluC	5.4.99.24	-	J	ko:K06179	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HAPGPGAE_01191	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HAPGPGAE_01192	1.14e-74	hinT	-	-	FG	ko:K02503	-	ko00000,ko04147	Psort location Cytoplasmic, score
HAPGPGAE_01193	6.61e-123	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Psort location Cytoplasmic, score
HAPGPGAE_01194	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Psort location CytoplasmicMembrane, score
HAPGPGAE_01195	6.65e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Psort location Cytoplasmic, score
HAPGPGAE_01196	6.2e-140	rnmV	3.1.26.8	-	L	ko:K05985	-	ko00000,ko01000	Ribonuclease M5
HAPGPGAE_01197	1.85e-75	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_01198	2.76e-90	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HAPGPGAE_01199	1e-96	mgrA	-	-	K	-	-	-	Transcriptional regulators
HAPGPGAE_01200	1.02e-171	-	-	-	F	-	-	-	Radical SAM domain protein
HAPGPGAE_01201	2.39e-227	-	-	-	L	-	-	-	Radical SAM domain protein
HAPGPGAE_01202	5.07e-10	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HAPGPGAE_01203	6.79e-40	-	-	-	L	-	-	-	Integrase core domain
HAPGPGAE_01204	1e-47	yeiR	-	-	P	-	-	-	cobalamin synthesis protein
HAPGPGAE_01205	8.77e-151	-	-	-	S	-	-	-	Membrane
HAPGPGAE_01206	4.87e-123	-	-	-	Q	-	-	-	Isochorismatase family
HAPGPGAE_01207	8.09e-122	-	-	-	S	-	-	-	domain protein
HAPGPGAE_01208	5.68e-156	sfsA	-	-	S	ko:K06206	-	ko00000	Belongs to the SfsA family
HAPGPGAE_01209	1.31e-88	-	1.15.1.2	-	C	ko:K05919	-	ko00000,ko01000	Desulfoferrodoxin
HAPGPGAE_01210	1.91e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF523)
HAPGPGAE_01211	1.26e-49	-	-	-	S	-	-	-	HAD hydrolase, family IIB
HAPGPGAE_01212	1.83e-105	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_01213	6.46e-109	pth_2	3.1.1.29	-	S	ko:K04794	-	ko00000,ko01000,ko03012	Peptidyl-tRNA hydrolase
HAPGPGAE_01214	7.2e-32	bioH	-	-	I	-	-	-	carboxylic ester hydrolase activity
HAPGPGAE_01215	9.03e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF5131)
HAPGPGAE_01216	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
HAPGPGAE_01217	3.07e-200	punA	2.4.2.1	-	F	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HAPGPGAE_01218	1.74e-74	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HAPGPGAE_01219	1.29e-110	hsp18	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HAPGPGAE_01220	1.81e-258	-	-	-	C	ko:K18369	ko00640,map00640	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HAPGPGAE_01221	6.02e-118	msrA	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAPGPGAE_01222	3.18e-13	-	-	-	S	ko:K07150	-	ko00000	membrane
HAPGPGAE_01223	5.59e-114	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01224	8.17e-124	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	Hydrolase, NUDIX family
HAPGPGAE_01225	6.33e-46	-	-	-	D	-	-	-	Filamentation induced by cAMP protein fic
HAPGPGAE_01226	2.84e-143	-	-	-	Q	-	-	-	DREV methyltransferase
HAPGPGAE_01227	7.27e-145	-	-	-	Q	ko:K15256	-	ko00000,ko01000,ko03016	Methyltransferase domain protein
HAPGPGAE_01228	2.46e-217	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_01229	1.3e-176	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
HAPGPGAE_01230	1.26e-216	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase PanE/ApbA
HAPGPGAE_01231	3.06e-150	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
HAPGPGAE_01232	9.25e-142	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
HAPGPGAE_01233	6.33e-109	-	-	-	-	-	-	-	-
HAPGPGAE_01234	4e-171	-	-	-	-	-	-	-	-
HAPGPGAE_01235	9.78e-38	-	-	-	S	ko:K09163	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HAPGPGAE_01237	2.07e-122	-	-	-	K	-	-	-	DNA binding
HAPGPGAE_01238	1.45e-85	-	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HAPGPGAE_01239	6.05e-53	-	-	-	-	-	-	-	-
HAPGPGAE_01240	6.01e-272	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01241	1.26e-107	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAPGPGAE_01242	5.36e-96	-	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma-70 region 2
HAPGPGAE_01243	2.66e-205	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HAPGPGAE_01244	7.81e-209	-	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
HAPGPGAE_01245	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HAPGPGAE_01246	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HAPGPGAE_01247	1.65e-107	-	-	-	-	-	-	-	-
HAPGPGAE_01249	1.64e-90	-	1.15.1.2	-	C	ko:K05919	-	ko00000,ko01000	Superoxide reductase
HAPGPGAE_01250	5.03e-256	-	-	-	T	-	-	-	domain protein
HAPGPGAE_01251	3.43e-156	-	-	-	S	-	-	-	von Willebrand factor (vWF) type A domain
HAPGPGAE_01252	7.51e-159	nnrE	5.1.99.6	-	G	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HAPGPGAE_01253	5.52e-241	-	-	-	S	-	-	-	domain protein
HAPGPGAE_01255	7.72e-180	-	-	-	C	-	-	-	4Fe-4S binding domain
HAPGPGAE_01256	7.89e-187	-	-	-	S	-	-	-	Putative cyclase
HAPGPGAE_01257	3.86e-38	ywhH	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Cys-tRNA(Pro) hydrolase activity
HAPGPGAE_01258	5.47e-196	-	-	-	-	-	-	-	-
HAPGPGAE_01259	7.04e-174	gufA	-	-	P	ko:K07238	-	ko00000,ko02000	Metal cation transporter, ZIP family
HAPGPGAE_01260	3.09e-144	-	-	-	Q	ko:K15256	-	ko00000,ko01000,ko03016	Methyltransferase domain protein
HAPGPGAE_01261	2.24e-114	-	-	-	G	-	-	-	Ricin-type beta-trefoil
HAPGPGAE_01262	3.6e-316	-	-	-	V	-	-	-	MatE
HAPGPGAE_01264	1.01e-226	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	PBP superfamily domain
HAPGPGAE_01265	4.66e-117	-	-	-	S	-	-	-	Psort location
HAPGPGAE_01266	9.72e-147	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HAPGPGAE_01267	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HAPGPGAE_01268	0.0	-	-	-	C	-	-	-	FeS-containing Cyanobacterial-specific oxidoreductase
HAPGPGAE_01269	8.45e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HAPGPGAE_01270	8.53e-120	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HAPGPGAE_01271	5.13e-87	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01272	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HAPGPGAE_01273	4.93e-286	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HAPGPGAE_01275	9.64e-317	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	tRNA methylthiotransferase YqeV
HAPGPGAE_01276	0.0	-	-	-	C	-	-	-	4Fe-4S binding domain protein
HAPGPGAE_01279	5.26e-162	-	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Pyridoxal kinase
HAPGPGAE_01280	2.18e-127	trmL	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HAPGPGAE_01281	7.03e-214	-	-	-	S	-	-	-	EDD domain protein, DegV family
HAPGPGAE_01282	2.71e-233	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAPGPGAE_01283	1.96e-315	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine aminocarboxypropyltransferase cysteine synthase
HAPGPGAE_01284	4.1e-143	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type metal ion transport system permease component
HAPGPGAE_01285	1.72e-208	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HAPGPGAE_01286	9.14e-192	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HAPGPGAE_01287	4.99e-180	-	-	-	S	-	-	-	Putative threonine/serine exporter
HAPGPGAE_01288	7.48e-92	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HAPGPGAE_01290	1.94e-130	-	-	-	C	-	-	-	Nitroreductase family
HAPGPGAE_01291	7.47e-162	artP	-	-	ET	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HAPGPGAE_01292	6.48e-167	ArtM	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	acid ABC transporter
HAPGPGAE_01293	1.73e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC-type polar amino acid transport system ATPase component
HAPGPGAE_01294	8.14e-265	leuB	1.1.1.85	-	C	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HAPGPGAE_01295	7.69e-115	leuD	4.2.1.33, 4.2.1.35, 4.2.1.85	-	E	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAPGPGAE_01296	1.94e-308	leuC	4.2.1.33, 4.2.1.35, 4.2.1.85	-	E	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAPGPGAE_01297	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HAPGPGAE_01298	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HAPGPGAE_01300	6.31e-310	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine
HAPGPGAE_01301	3e-291	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Major Facilitator
HAPGPGAE_01302	2.72e-194	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01303	5.48e-206	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HAPGPGAE_01304	1.87e-148	-	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	amino acid ABC transporter
HAPGPGAE_01305	5.62e-183	tcyN	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Amino acid ABC transporter ATP-binding protein, PAAT family
HAPGPGAE_01306	3.01e-187	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Amino acid ABC transporter substrate-binding protein, PAAT family (TC 3.A.1.3.-)
HAPGPGAE_01307	4.06e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
HAPGPGAE_01308	2.44e-186	-	-	-	U	-	-	-	Protein of unknown function (DUF1700)
HAPGPGAE_01309	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HAPGPGAE_01310	4.88e-54	ptsH	-	-	G	ko:K11184,ko:K11189	-	ko00000,ko02000	phosphocarrier, HPr family
HAPGPGAE_01311	1e-316	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HAPGPGAE_01312	9.81e-129	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HAPGPGAE_01313	4.87e-45	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HAPGPGAE_01314	1.59e-49	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HAPGPGAE_01315	4.48e-312	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HAPGPGAE_01316	2.82e-83	-	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HAPGPGAE_01317	6.49e-171	-	-	-	E	-	-	-	Pyridoxal-phosphate dependent protein
HAPGPGAE_01318	4.79e-307	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
HAPGPGAE_01319	2.42e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HAPGPGAE_01320	4.35e-205	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HAPGPGAE_01322	3.07e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HAPGPGAE_01323	5.74e-21	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HAPGPGAE_01324	2.7e-36	-	-	-	K	-	-	-	Transcriptional regulator
HAPGPGAE_01326	2.83e-201	-	-	-	IQ	-	-	-	short chain dehydrogenase
HAPGPGAE_01327	8.43e-225	-	-	-	M	-	-	-	Domain of unknown function (DUF4349)
HAPGPGAE_01328	1.27e-115	-	-	-	K	ko:K03088	-	ko00000,ko03021	Putative ATPase subunit of terminase (gpP-like)
HAPGPGAE_01331	6.31e-124	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HAPGPGAE_01332	6.74e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HAPGPGAE_01333	2.58e-117	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
HAPGPGAE_01335	0.0	fusA2	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	translation elongation
HAPGPGAE_01336	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	asparagine synthase (glutamine-hydrolyzing)
HAPGPGAE_01337	1.05e-117	-	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HAPGPGAE_01338	1.56e-152	-	-	-	K	-	-	-	FCD
HAPGPGAE_01339	3.12e-183	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HAPGPGAE_01340	1.81e-203	-	-	-	P	ko:K05832	-	ko00000,ko00002,ko02000	Branched-chain amino acid ABC transporter, permease protein
HAPGPGAE_01341	2.35e-232	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
HAPGPGAE_01342	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01343	1.47e-136	yfbR	3.1.3.89	-	S	ko:K07023,ko:K08722	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	PFAM metal-dependent phosphohydrolase HD sub domain
HAPGPGAE_01344	2.76e-247	dus	-	-	H	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAPGPGAE_01345	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HAPGPGAE_01346	6.53e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HAPGPGAE_01347	9.85e-197	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HAPGPGAE_01348	5.34e-269	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HAPGPGAE_01349	1.26e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HAPGPGAE_01350	4.49e-46	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HAPGPGAE_01351	8.66e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HAPGPGAE_01352	2.8e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HAPGPGAE_01353	1.68e-157	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HAPGPGAE_01354	5.93e-113	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HAPGPGAE_01355	4.31e-63	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HAPGPGAE_01356	4.05e-208	-	-	-	S	-	-	-	Phospholipase, patatin family
HAPGPGAE_01357	4.05e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HAPGPGAE_01358	0.0	spoVD	3.4.16.4	-	M	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein
HAPGPGAE_01359	3.44e-233	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HAPGPGAE_01360	4.84e-312	murA2	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HAPGPGAE_01361	3.23e-254	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HAPGPGAE_01363	0.0	-	-	-	T	ko:K07814	-	ko00000,ko02022	HD domain
HAPGPGAE_01364	1.76e-160	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine O-acetyltransferase
HAPGPGAE_01366	5.84e-296	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HAPGPGAE_01367	1.25e-206	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
HAPGPGAE_01368	1.64e-191	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HAPGPGAE_01369	4.4e-217	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HAPGPGAE_01370	3.09e-139	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HAPGPGAE_01371	1.37e-273	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HAPGPGAE_01372	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HAPGPGAE_01373	5.07e-62	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	bacterial (prokaryotic) histone like domain
HAPGPGAE_01374	1.59e-288	cshA	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	Belongs to the DEAD box helicase family
HAPGPGAE_01375	6.3e-142	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HAPGPGAE_01376	3.13e-62	-	-	-	S	-	-	-	Putative heavy-metal-binding
HAPGPGAE_01377	6.51e-216	-	-	-	S	-	-	-	CAAX protease self-immunity
HAPGPGAE_01378	1.74e-189	-	-	-	O	ko:K03697	-	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
HAPGPGAE_01379	7.68e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HAPGPGAE_01380	8.89e-101	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01381	0.0	gltX	6.1.1.17, 6.1.1.24	-	J	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HAPGPGAE_01382	5.13e-64	-	-	-	-	-	-	-	-
HAPGPGAE_01383	1.06e-66	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
HAPGPGAE_01384	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HAPGPGAE_01385	3.87e-238	-	3.1.1.11	-	G	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Pectinesterase
HAPGPGAE_01387	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAPGPGAE_01388	3.29e-163	resD	-	-	K	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HAPGPGAE_01389	0.0	-	2.3.1.79	-	M	ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide (six repeats)
HAPGPGAE_01390	8.15e-301	-	3.1.1.17	-	G	ko:K01053,ko:K02352	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	ko00000,ko00001,ko00002,ko01000,ko04147	gluconolactonase activity
HAPGPGAE_01391	2.2e-129	-	-	-	S	-	-	-	Belongs to the UPF0340 family
HAPGPGAE_01392	2.67e-163	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HAPGPGAE_01393	0.0	-	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HAPGPGAE_01394	5.08e-210	-	-	-	S	-	-	-	Patatin-like phospholipase
HAPGPGAE_01398	9.11e-250	-	-	-	M	-	-	-	lipoprotein YddW precursor K01189
HAPGPGAE_01399	2.71e-122	-	-	-	-	-	-	-	-
HAPGPGAE_01400	8.81e-211	-	-	-	EG	-	-	-	EamA-like transporter family
HAPGPGAE_01401	1.14e-130	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
HAPGPGAE_01402	0.0	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HAPGPGAE_01403	1.22e-300	-	-	-	T	-	-	-	Protein of unknown function (DUF1538)
HAPGPGAE_01404	3.27e-150	-	-	-	K	-	-	-	Belongs to the P(II) protein family
HAPGPGAE_01405	2.29e-195	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01406	4.95e-57	-	-	-	C	-	-	-	Hydrid cluster protein-associated redox disulfide domain
HAPGPGAE_01407	3.03e-135	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HAPGPGAE_01408	2.02e-172	-	-	-	S	-	-	-	dinuclear metal center protein, YbgI
HAPGPGAE_01409	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HAPGPGAE_01410	6.56e-64	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HAPGPGAE_01411	1.34e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HAPGPGAE_01412	3.72e-145	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HAPGPGAE_01413	1.26e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HAPGPGAE_01414	5.3e-202	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HAPGPGAE_01415	2.9e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HAPGPGAE_01416	1.01e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HAPGPGAE_01417	1.33e-165	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HAPGPGAE_01418	1.42e-101	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HAPGPGAE_01419	9.04e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HAPGPGAE_01420	2.02e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HAPGPGAE_01421	1.31e-81	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HAPGPGAE_01422	1.66e-71	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HAPGPGAE_01423	6.11e-129	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HAPGPGAE_01424	1.67e-38	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HAPGPGAE_01426	2.77e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HAPGPGAE_01427	1.05e-130	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HAPGPGAE_01428	3.26e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HAPGPGAE_01429	6.22e-108	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HAPGPGAE_01430	1.83e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein
HAPGPGAE_01431	2.45e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HAPGPGAE_01432	3.22e-288	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HAPGPGAE_01433	5.7e-146	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HAPGPGAE_01434	2.58e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HAPGPGAE_01435	8.01e-59	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HAPGPGAE_01436	7.03e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HAPGPGAE_01437	3.34e-80	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HAPGPGAE_01438	1.25e-88	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HAPGPGAE_01439	4.36e-136	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HAPGPGAE_01440	3.11e-222	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAPGPGAE_01441	2.75e-72	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HAPGPGAE_01442	2.09e-303	-	-	-	S	-	-	-	Tetratricopeptide repeat
HAPGPGAE_01443	8.65e-162	-	-	-	K	-	-	-	response regulator receiver
HAPGPGAE_01444	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HAPGPGAE_01445	4.64e-227	prmC	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01446	2.48e-226	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HAPGPGAE_01447	8.84e-266	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HAPGPGAE_01448	1.14e-102	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HAPGPGAE_01449	0.0	rimO	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
HAPGPGAE_01450	2.73e-134	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAPGPGAE_01451	1.47e-56	rhaA	5.3.1.14	-	G	ko:K01813	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
HAPGPGAE_01452	1.06e-242	rhaA	5.3.1.14	-	G	ko:K01813	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
HAPGPGAE_01453	8.2e-210	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HAPGPGAE_01454	2.34e-207	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HAPGPGAE_01455	2.61e-155	effD	-	-	V	-	-	-	MatE
HAPGPGAE_01456	6.82e-149	-	1.1.1.100, 1.1.1.30	-	IQ	ko:K00019,ko:K00059	ko00061,ko00072,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00072,map00333,map00650,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HAPGPGAE_01457	6.49e-18	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01458	1.23e-309	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HAPGPGAE_01459	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
HAPGPGAE_01460	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 2
HAPGPGAE_01461	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HAPGPGAE_01462	3.74e-205	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HAPGPGAE_01463	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain protein
HAPGPGAE_01464	5.82e-272	-	-	-	G	-	-	-	Major Facilitator Superfamily
HAPGPGAE_01465	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HAPGPGAE_01466	1.6e-289	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01467	2.83e-110	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
HAPGPGAE_01468	7.82e-240	-	-	-	M	-	-	-	Bacterial extracellular solute-binding protein, family 7
HAPGPGAE_01469	1.97e-84	-	-	-	K	-	-	-	Cupin domain
HAPGPGAE_01471	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HAPGPGAE_01472	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2264)
HAPGPGAE_01473	8.28e-298	-	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HAPGPGAE_01474	0.0	-	3.2.1.23, 3.2.1.31	-	G	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolases family 2
HAPGPGAE_01475	2.32e-201	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Carbohydrate ABC transporter membrane protein 2, CUT1 family
HAPGPGAE_01476	4.1e-222	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC transporter
HAPGPGAE_01477	3.18e-299	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Carbohydrate ABC transporter substrate-binding protein, CUT1 family (TC 3.A.1.1.-)
HAPGPGAE_01478	1.27e-193	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902 family protein
HAPGPGAE_01479	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HAPGPGAE_01480	1.46e-299	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HAPGPGAE_01481	0.0	-	-	-	S	-	-	-	Heparinase II/III-like protein
HAPGPGAE_01482	2.15e-195	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01483	0.0	-	-	-	-	-	-	-	-
HAPGPGAE_01484	3.41e-119	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HAPGPGAE_01485	7.76e-314	-	-	-	S	-	-	-	Putative threonine/serine exporter
HAPGPGAE_01486	6.12e-179	-	-	-	S	-	-	-	Domain of unknown function (DUF4866)
HAPGPGAE_01487	3.65e-37	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HAPGPGAE_01488	2.07e-117	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HAPGPGAE_01489	4.93e-24	-	3.2.1.17	-	G	ko:K01185	-	ko00000,ko01000	lysozyme
HAPGPGAE_01491	6.54e-32	-	-	-	K	ko:K03086,ko:K03091	-	ko00000,ko03021	Sigma-70 region 2
HAPGPGAE_01492	5.39e-186	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAPGPGAE_01493	8.68e-265	-	-	-	D	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01494	5.16e-57	-	-	-	L	-	-	-	Helix-turn-helix domain
HAPGPGAE_01495	0.0	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGPGAE_01498	9.35e-183	tig_1	-	-	O	ko:K03545	-	ko00000	peptidylprolyl isomerase
HAPGPGAE_01499	1.29e-280	-	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HAPGPGAE_01500	2.33e-202	fumA	4.2.1.2	-	C	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type
HAPGPGAE_01501	5.19e-127	fumB	4.2.1.2	-	C	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Hydrolyase, tartrate beta subunit fumarate domain protein, Fe-S type
HAPGPGAE_01502	1.14e-83	-	-	-	K	-	-	-	iron dependent repressor
HAPGPGAE_01503	2.78e-273	-	-	-	T	-	-	-	diguanylate cyclase
HAPGPGAE_01504	0.0	-	2.7.11.1	-	KL	ko:K08282	-	ko00000,ko01000	SNF2 family
HAPGPGAE_01505	3.2e-241	-	3.4.13.19	-	E	ko:K01273	-	ko00000,ko00537,ko01000,ko01002,ko04147	Renal dipeptidase family protein
HAPGPGAE_01506	2.77e-174	yfcA	-	-	S	ko:K07090	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_01507	1.24e-200	-	-	-	S	-	-	-	EDD domain protein, DegV family
HAPGPGAE_01508	1.14e-83	-	-	-	S	ko:K07052	-	ko00000	Psort location CytoplasmicMembrane, score
HAPGPGAE_01509	7.6e-118	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HAPGPGAE_01510	3.31e-150	fabG5	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HAPGPGAE_01511	2.29e-308	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HAPGPGAE_01512	1.25e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HAPGPGAE_01513	2.34e-88	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HAPGPGAE_01514	7.23e-51	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HAPGPGAE_01515	3.53e-227	-	-	-	H	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAPGPGAE_01517	9.27e-220	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HAPGPGAE_01518	1.49e-97	-	-	-	K	-	-	-	Transcriptional regulator
HAPGPGAE_01519	1.49e-104	-	-	-	L	-	-	-	Nuclease-related domain
HAPGPGAE_01520	1.43e-44	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
HAPGPGAE_01521	6.21e-151	lrgB	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01522	8.54e-54	-	-	-	P	-	-	-	mercury ion transmembrane transporter activity
HAPGPGAE_01523	1.92e-204	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01524	0.0	malP_1	2.4.1.1	GT35	F	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HAPGPGAE_01525	5.51e-158	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HAPGPGAE_01526	2.4e-33	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03425	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein secretion
HAPGPGAE_01527	8.62e-45	-	-	-	U	ko:K03117	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	mttA/Hcf106 family
HAPGPGAE_01528	0.0	-	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC-type multidrug transport system ATPase and permease
HAPGPGAE_01529	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HAPGPGAE_01530	2.3e-251	-	-	-	S	-	-	-	Sel1-like repeats.
HAPGPGAE_01531	0.0	-	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HAPGPGAE_01532	3.2e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF1653)
HAPGPGAE_01533	9.67e-229	-	-	-	-	-	-	-	-
HAPGPGAE_01534	5.15e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HAPGPGAE_01535	2.61e-196	-	-	-	S	-	-	-	Cof-like hydrolase
HAPGPGAE_01536	2.02e-249	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01537	2.23e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
HAPGPGAE_01538	2.27e-219	tig	-	-	D	ko:K03545	-	ko00000	peptidyl-prolyl cis-trans isomerase activity
HAPGPGAE_01541	1.66e-232	-	-	-	S	-	-	-	Leucine rich repeats (6 copies)
HAPGPGAE_01542	0.0	-	-	-	S	-	-	-	VWA-like domain (DUF2201)
HAPGPGAE_01543	0.0	-	-	-	S	-	-	-	AAA domain (dynein-related subfamily)
HAPGPGAE_01544	1.6e-103	nifU	-	-	C	ko:K04488	-	ko00000	Fe-S iron-sulfur cluster assembly protein, NifU family
HAPGPGAE_01545	2.49e-297	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins
HAPGPGAE_01546	6.81e-111	-	-	-	-	-	-	-	-
HAPGPGAE_01547	3.71e-74	-	-	-	P	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_01548	1.34e-109	-	-	-	K	-	-	-	Transcriptional regulator
HAPGPGAE_01552	3.3e-302	adh	-	-	C	-	-	-	belongs to the iron- containing alcohol dehydrogenase family
HAPGPGAE_01553	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HAPGPGAE_01554	7.27e-101	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HAPGPGAE_01555	3.62e-83	cas6	-	-	S	-	-	-	CRISPR-associated endoribonuclease Cas6
HAPGPGAE_01556	8.67e-97	csm5	-	-	L	ko:K19140	-	ko00000,ko02048	RAMP superfamily
HAPGPGAE_01557	3e-119	csm4	-	-	L	ko:K19139	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm4 family
HAPGPGAE_01558	4.58e-93	csm3	-	-	L	ko:K09002	-	ko00000,ko02048	RAMP superfamily
HAPGPGAE_01559	2.56e-25	csm2	-	-	L	ko:K19138	-	ko00000,ko02048	CRISPR-associated protein, Csm2 family
HAPGPGAE_01560	1.38e-206	csm1	-	-	J	ko:K07016	-	ko00000,ko02048	crispr-associated protein
HAPGPGAE_01562	5.82e-59	-	-	-	S	-	-	-	CRISPR-associated (Cas) DxTHG family
HAPGPGAE_01564	3.94e-153	-	-	-	L	-	-	-	CRISPR-associated (Cas) DxTHG family
HAPGPGAE_01565	4.39e-274	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
HAPGPGAE_01566	4.63e-37	rpoD	-	-	K	ko:K03086,ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAPGPGAE_01567	0.0	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
HAPGPGAE_01568	0.0	-	-	-	G	-	-	-	KAP family P-loop domain
HAPGPGAE_01569	2.32e-118	-	-	-	-	-	-	-	-
HAPGPGAE_01570	2.91e-283	-	-	-	F	-	-	-	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HAPGPGAE_01571	1.36e-129	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HAPGPGAE_01572	3.55e-193	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01573	6.89e-208	-	-	-	S	ko:K03453	-	ko00000	Psort location CytoplasmicMembrane, score
HAPGPGAE_01574	2.9e-275	pdxB	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
HAPGPGAE_01575	6.21e-266	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HAPGPGAE_01576	6.63e-95	-	-	-	K	-	-	-	Transcriptional regulator, BlaI MecI CopY family
HAPGPGAE_01577	0.0	gltA2	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	citrate synthase
HAPGPGAE_01578	8.46e-96	-	-	-	-	-	-	-	-
HAPGPGAE_01579	1.2e-214	-	-	-	J	ko:K02238	-	ko00000,ko00002,ko02044	Metallo-beta-lactamase domain protein
HAPGPGAE_01580	0.0	-	-	-	C	-	-	-	UPF0313 protein
HAPGPGAE_01581	0.0	spoIIIE	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HAPGPGAE_01582	1.45e-161	tepA	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score
HAPGPGAE_01583	8.11e-152	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HAPGPGAE_01584	3.34e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HAPGPGAE_01585	0.0	-	-	-	G	ko:K02027,ko:K10192	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAPGPGAE_01586	3.8e-223	-	-	-	P	ko:K02025,ko:K10193	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate ABC transporter membrane protein 1 CUT1 family
HAPGPGAE_01587	1.99e-210	-	-	-	P	ko:K10194	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPGPGAE_01588	1.14e-172	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPGPGAE_01589	0.0	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
HAPGPGAE_01590	8.54e-295	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HAPGPGAE_01591	1.49e-156	-	-	-	M	-	-	-	Peptidase, M23 family
HAPGPGAE_01592	1.56e-246	-	-	-	G	-	-	-	Major Facilitator Superfamily
HAPGPGAE_01593	3.05e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGPGAE_01594	5.37e-307	-	-	-	S	ko:K07007	-	ko00000	Flavoprotein family
HAPGPGAE_01595	1.28e-148	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HAPGPGAE_01596	2.01e-147	plsC_1	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HAPGPGAE_01597	1.31e-183	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain
HAPGPGAE_01598	1.63e-199	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HAPGPGAE_01599	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HAPGPGAE_01602	5.26e-156	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	phosphoglycolate phosphatase, bacterial
HAPGPGAE_01603	0.0	-	-	-	-	-	-	-	-
HAPGPGAE_01605	1.1e-158	-	-	-	C	ko:K03499	-	ko00000,ko02000	TrkA N-terminal domain protein
HAPGPGAE_01606	1.07e-94	trkA2	-	-	C	ko:K03499	-	ko00000,ko02000	TrkA N-terminal domain protein
HAPGPGAE_01607	5.92e-178	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HAPGPGAE_01608	2.77e-263	clcA	-	-	P	ko:K03281	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_01609	3.74e-265	-	-	-	C	ko:K07138	-	ko00000	Psort location Cytoplasmic, score
HAPGPGAE_01610	5.92e-118	-	-	-	-	-	-	-	-
HAPGPGAE_01611	8.07e-191	licT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	Psort location Cytoplasmic, score
HAPGPGAE_01612	0.0	glvC	2.7.1.199, 2.7.1.208	-	G	ko:K02749,ko:K02750,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_01613	0.0	-	3.2.1.122, 3.2.1.86	GH4,GT4	G	ko:K01222,ko:K01232	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HAPGPGAE_01614	1.35e-239	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon
HAPGPGAE_01615	3.54e-116	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01616	4.25e-306	-	-	-	V	-	-	-	MATE efflux family protein
HAPGPGAE_01618	0.0	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	CBS domain
HAPGPGAE_01619	3.74e-69	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HAPGPGAE_01622	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01623	9.83e-134	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
HAPGPGAE_01624	0.0	-	-	-	S	-	-	-	DNA replication and repair protein RecF
HAPGPGAE_01625	9.84e-299	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01626	3.98e-126	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HAPGPGAE_01628	1.86e-215	-	-	-	K	-	-	-	LysR substrate binding domain
HAPGPGAE_01629	0.0	cstA	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01630	5.45e-233	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01631	8.21e-216	-	-	-	K	-	-	-	LysR substrate binding domain
HAPGPGAE_01632	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN_bind
HAPGPGAE_01633	1.87e-305	-	-	-	V	-	-	-	MviN-like protein
HAPGPGAE_01634	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01637	3.5e-171	-	-	-	-	-	-	-	-
HAPGPGAE_01641	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_01642	3.21e-193	ytrP	2.7.7.65	-	T	ko:K13069	-	ko00000,ko01000	diguanylate cyclase activity
HAPGPGAE_01643	7.62e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01644	6.87e-229	-	-	-	JM	-	-	-	Nucleotidyl transferase
HAPGPGAE_01645	7.26e-115	-	-	-	J	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01646	1.17e-82	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPGPGAE_01647	2.57e-148	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HAPGPGAE_01648	6.61e-181	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HAPGPGAE_01649	6.09e-176	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate ABC transporter
HAPGPGAE_01650	2.1e-197	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HAPGPGAE_01651	8.01e-171	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate binding protein
HAPGPGAE_01656	3.7e-259	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HAPGPGAE_01657	2.58e-179	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HAPGPGAE_01658	3.41e-190	-	1.1.1.69	-	IQ	ko:K00046	-	ko00000,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_01659	7.52e-84	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HAPGPGAE_01660	8.12e-151	-	-	-	G	-	-	-	Ribose Galactose Isomerase
HAPGPGAE_01661	8.75e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1622)
HAPGPGAE_01662	0.0	-	-	-	P	ko:K03320	-	ko00000,ko02000	Belongs to the P(II) protein family
HAPGPGAE_01663	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HAPGPGAE_01664	8.89e-100	-	-	-	-	-	-	-	-
HAPGPGAE_01665	3.61e-270	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HAPGPGAE_01667	5.68e-287	rny	-	-	D	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HAPGPGAE_01668	4.29e-135	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01669	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 3 family
HAPGPGAE_01670	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HAPGPGAE_01671	3.44e-300	-	-	-	T	-	-	-	GHKL domain
HAPGPGAE_01672	9.01e-165	-	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HAPGPGAE_01673	7.1e-139	-	-	-	U	-	-	-	domain, Protein
HAPGPGAE_01674	4.62e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HAPGPGAE_01675	9.07e-177	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HAPGPGAE_01676	4.44e-173	-	-	-	K	ko:K02081	-	ko00000,ko03000	DeoR C terminal sensor domain
HAPGPGAE_01677	8.02e-226	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
HAPGPGAE_01678	0.0	-	-	-	H	ko:K03483	-	ko00000,ko03000	PRD domain
HAPGPGAE_01679	0.0	mtlA	2.7.1.197	-	G	ko:K02798,ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system
HAPGPGAE_01680	1.88e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
HAPGPGAE_01681	1.56e-54	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HAPGPGAE_01682	4.37e-39	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HAPGPGAE_01683	4.34e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HAPGPGAE_01684	2.39e-181	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAPGPGAE_01685	2.09e-215	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HAPGPGAE_01686	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HAPGPGAE_01687	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HAPGPGAE_01688	8.79e-239	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HAPGPGAE_01689	8.34e-155	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HAPGPGAE_01690	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HAPGPGAE_01691	4.93e-216	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HAPGPGAE_01692	4.89e-152	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HAPGPGAE_01693	8.86e-62	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein, YhbY family
HAPGPGAE_01694	7.75e-145	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HAPGPGAE_01695	1.08e-132	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	HD superfamily hydrolase involved in NAD metabolism
HAPGPGAE_01696	1.26e-281	-	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HAPGPGAE_01697	1.39e-83	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HAPGPGAE_01698	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HAPGPGAE_01699	5.46e-27	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HAPGPGAE_01700	2.75e-116	yqeG	-	-	S	ko:K07015	-	ko00000	Mitochondrial PGP phosphatase
HAPGPGAE_01701	8.16e-185	Nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV
HAPGPGAE_01702	1.81e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HAPGPGAE_01703	3.08e-74	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01704	3.13e-65	-	-	-	-	-	-	-	-
HAPGPGAE_01705	2.45e-214	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HAPGPGAE_01706	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HAPGPGAE_01707	7.68e-274	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	aminotransferase class V
HAPGPGAE_01708	4.49e-282	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HAPGPGAE_01709	1.88e-307	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HAPGPGAE_01712	2.79e-106	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HAPGPGAE_01713	0.0	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGPGAE_01714	8.72e-208	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01715	1.33e-183	-	-	-	K	-	-	-	Toxic component of a toxin-antitoxin (TA) module
HAPGPGAE_01716	1.65e-171	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HAPGPGAE_01717	1.68e-60	-	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	sequence-specific DNA binding
HAPGPGAE_01718	1.75e-166	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HAPGPGAE_01719	3.62e-97	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01720	0.0	-	-	-	V	-	-	-	antibiotic catabolic process
HAPGPGAE_01721	4.18e-77	-	-	-	KT	-	-	-	Response regulator of the LytR AlgR family
HAPGPGAE_01722	9.01e-114	-	-	-	KT	-	-	-	LytTr DNA-binding domain
HAPGPGAE_01723	1.02e-287	-	-	-	T	-	-	-	GHKL domain
HAPGPGAE_01724	1.46e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HAPGPGAE_01725	5.62e-55	-	-	-	S	-	-	-	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121
HAPGPGAE_01726	0.0	copA_1	-	-	P	ko:K12950	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
HAPGPGAE_01727	4.75e-214	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_01728	1.09e-93	-	-	-	S	-	-	-	FMN_bind
HAPGPGAE_01729	1.38e-214	-	-	-	C	-	-	-	FMN-binding domain protein
HAPGPGAE_01730	1.86e-302	-	-	-	S	-	-	-	Penicillin-binding protein Tp47 domain a
HAPGPGAE_01731	0.0	-	-	-	V	-	-	-	MATE efflux family protein
HAPGPGAE_01732	7.51e-189	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HAPGPGAE_01733	4.26e-108	-	-	-	S	-	-	-	small multi-drug export protein
HAPGPGAE_01734	0.0	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_01735	4.49e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF3842)
HAPGPGAE_01736	4.41e-133	-	-	-	S	-	-	-	metal-dependent phosphohydrolase, HD sub domain
HAPGPGAE_01737	2.29e-48	-	-	-	S	-	-	-	Transcriptional Coactivator p15 (PC4)
HAPGPGAE_01739	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	exonuclease SbcC
HAPGPGAE_01740	1.45e-226	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HAPGPGAE_01741	1.76e-109	-	-	-	M	-	-	-	Putative peptidoglycan binding domain
HAPGPGAE_01742	1.1e-139	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HAPGPGAE_01743	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HAPGPGAE_01744	4.12e-56	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HAPGPGAE_01745	2.04e-105	Lrp	-	-	K	-	-	-	Transcriptional regulator, AsnC family
HAPGPGAE_01746	7.61e-291	aspC	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
HAPGPGAE_01747	3.55e-200	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HAPGPGAE_01748	1.58e-30	-	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HAPGPGAE_01749	2.08e-159	-	-	-	-	-	-	-	-
HAPGPGAE_01750	3.5e-64	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_01751	1.28e-166	-	5.2.1.8	-	M	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAPGPGAE_01752	8.64e-97	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HAPGPGAE_01753	0.0	addB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
HAPGPGAE_01754	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HAPGPGAE_01755	1.08e-87	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HAPGPGAE_01756	1.57e-189	-	-	-	U	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_01757	1.09e-89	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HAPGPGAE_01758	3.33e-208	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
HAPGPGAE_01759	4.87e-47	-	-	-	-	-	-	-	-
HAPGPGAE_01760	1.1e-98	-	-	-	-	-	-	-	-
HAPGPGAE_01761	0.0	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
HAPGPGAE_01762	1.03e-50	-	-	-	-	-	-	-	-
HAPGPGAE_01763	2.04e-223	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HAPGPGAE_01764	4.18e-262	-	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HAPGPGAE_01765	3.3e-228	oppC	-	-	P	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HAPGPGAE_01766	1.15e-193	oppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPGPGAE_01767	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HAPGPGAE_01768	1.39e-228	tktB	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyridine binding domain protein
HAPGPGAE_01769	4.04e-205	tktA	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, thiamine diphosphate binding domain
HAPGPGAE_01770	1.23e-113	-	-	-	S	ko:K16788	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HAPGPGAE_01771	1.52e-146	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HAPGPGAE_01772	0.0	-	3.1.3.48	-	K	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
HAPGPGAE_01773	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HAPGPGAE_01774	1.62e-275	-	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain
HAPGPGAE_01775	3.59e-206	-	-	-	JK	-	-	-	Acetyltransferase (GNAT) family
HAPGPGAE_01776	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HAPGPGAE_01777	3.33e-242	-	-	-	C	ko:K18471	ko00640,map00640	ko00000,ko00001,ko01000	Aldo/keto reductase family
HAPGPGAE_01778	3.32e-145	-	-	-	K	ko:K01420	-	ko00000,ko03000	Psort location Cytoplasmic, score
HAPGPGAE_01779	2.88e-190	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	pyridine
HAPGPGAE_01780	5.56e-245	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HAPGPGAE_01781	2.05e-63	azlD	-	-	E	-	-	-	branched-chain amino acid permeases (Azaleucine resistance)
HAPGPGAE_01782	2.34e-140	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
HAPGPGAE_01783	0.0	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HAPGPGAE_01784	4.33e-214	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01785	6.15e-40	-	-	-	S	-	-	-	Psort location
HAPGPGAE_01786	8.11e-191	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HAPGPGAE_01787	1.93e-285	alaXL	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Threonine alanine tRNA ligase second additional domain protein
HAPGPGAE_01788	0.0	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGPGAE_01789	1.67e-30	-	-	-	L	-	-	-	Helix-turn-helix domain
HAPGPGAE_01790	6.16e-297	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_01791	0.0	-	-	-	T	ko:K02667	ko02020,map02020	ko00000,ko00001,ko00002,ko02022,ko02035	phosphorelay signal transduction system
HAPGPGAE_01792	8.48e-284	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative sugar-binding N-terminal domain
HAPGPGAE_01793	7.39e-303	-	-	-	G	-	-	-	BNR repeat-like domain
HAPGPGAE_01794	1.76e-277	-	-	-	C	-	-	-	alcohol dehydrogenase
HAPGPGAE_01795	1.6e-217	-	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the DapA family
HAPGPGAE_01796	1.85e-265	pdxA	1.1.1.262, 1.1.1.408, 1.1.1.409	-	C	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the PdxA family
HAPGPGAE_01797	1.04e-286	-	-	-	P	-	-	-	arsenite transmembrane transporter activity
HAPGPGAE_01798	1.58e-81	-	-	-	G	-	-	-	Aldolase
HAPGPGAE_01799	4.84e-197	-	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger family protein
HAPGPGAE_01800	3.42e-199	-	-	-	K	-	-	-	transcriptional regulator RpiR family
HAPGPGAE_01801	1.76e-204	murQ	4.2.1.126	-	H	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HAPGPGAE_01802	0.0	-	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_01803	4.42e-249	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HAPGPGAE_01804	4.17e-314	-	-	-	V	-	-	-	MATE efflux family protein
HAPGPGAE_01805	1.58e-202	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_01806	1.57e-148	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HAPGPGAE_01807	3.99e-180	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HAPGPGAE_01808	1.18e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HAPGPGAE_01809	1.41e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HAPGPGAE_01810	6.5e-146	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HAPGPGAE_01811	2.11e-249	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HAPGPGAE_01812	2.06e-297	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HAPGPGAE_01813	0.0	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HAPGPGAE_01814	1.84e-86	-	-	-	S	ko:K08978	-	ko00000,ko02000	EamA-like transporter family
HAPGPGAE_01815	2.16e-103	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HAPGPGAE_01816	0.0	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01818	2.39e-85	-	3.1.2.29	-	S	ko:K18700	-	ko00000,ko01000	thioesterase
HAPGPGAE_01819	1.67e-72	ziaR	-	-	K	ko:K21903	-	ko00000,ko03000	regulatory protein, arsR
HAPGPGAE_01820	6.86e-45	-	-	-	C	-	-	-	Heavy metal-associated domain protein
HAPGPGAE_01821	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
HAPGPGAE_01822	0.0	-	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase
HAPGPGAE_01823	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	PFAM DNA gyrase topoisomerase IV, subunit A
HAPGPGAE_01824	1.6e-103	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HAPGPGAE_01825	5.86e-191	fliY1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HAPGPGAE_01826	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPGPGAE_01827	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HAPGPGAE_01828	3.67e-294	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HAPGPGAE_01829	1.31e-288	-	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HAPGPGAE_01830	6.64e-170	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01831	3.05e-236	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01832	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HAPGPGAE_01833	3.22e-94	-	-	-	S	-	-	-	NusG domain II
HAPGPGAE_01834	0.0	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
HAPGPGAE_01835	6.35e-176	macB	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HAPGPGAE_01836	1.27e-273	macB1	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HAPGPGAE_01837	0.0	-	-	-	F	-	-	-	S-layer homology domain
HAPGPGAE_01838	7.76e-189	comF	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
HAPGPGAE_01840	6.09e-53	-	-	-	-	-	-	-	-
HAPGPGAE_01841	1e-63	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPGPGAE_01842	3.35e-99	-	-	-	KT	ko:K02483	-	ko00000,ko02022	response regulator receiver
HAPGPGAE_01843	3.52e-257	-	-	-	C	-	-	-	succinate dehydrogenase
HAPGPGAE_01844	2.96e-120	-	-	-	M	-	-	-	Peptidase family S41
HAPGPGAE_01845	2.03e-224	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_01846	0.0	-	-	-	U	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_01847	1.02e-75	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HAPGPGAE_01848	1.44e-104	-	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Peptidase family M41
HAPGPGAE_01851	3.36e-42	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPGPGAE_01856	7.24e-244	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGPGAE_01857	3.16e-152	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAPGPGAE_01858	4.13e-112	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
HAPGPGAE_01859	3.14e-294	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01860	9.77e-278	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01861	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01867	2.53e-147	-	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Psort location Cytoplasmic, score
HAPGPGAE_01868	2.48e-25	-	-	-	-	-	-	-	-
HAPGPGAE_01869	2.61e-171	tsaA	-	-	S	-	-	-	Methyltransferase, YaeB family
HAPGPGAE_01870	6.97e-208	-	-	-	K	-	-	-	LysR substrate binding domain
HAPGPGAE_01871	2.37e-271	-	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HAPGPGAE_01872	8.82e-167	-	-	-	K	-	-	-	transcriptional regulator AraC family
HAPGPGAE_01873	9.46e-298	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01874	6.88e-231	scrK	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_01875	1.39e-119	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HAPGPGAE_01876	7.55e-48	-	-	-	-	-	-	-	-
HAPGPGAE_01877	2.41e-260	-	-	-	T	-	-	-	diguanylate cyclase
HAPGPGAE_01878	1e-274	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAPGPGAE_01879	1.17e-220	-	-	-	GK	-	-	-	ROK family
HAPGPGAE_01881	6.61e-97	-	-	-	-	-	-	-	-
HAPGPGAE_01882	6.39e-298	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HAPGPGAE_01883	1.28e-102	-	-	-	S	-	-	-	Pfam:DUF3816
HAPGPGAE_01884	0.0	pz-A	-	-	E	-	-	-	Peptidase family M3
HAPGPGAE_01887	1.25e-265	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HAPGPGAE_01888	4.41e-155	-	-	-	S	ko:K06890	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_01889	2.21e-192	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HAPGPGAE_01890	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HAPGPGAE_01891	3.22e-214	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_01892	6.52e-222	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_01893	2.11e-220	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the DapA family
HAPGPGAE_01894	2.97e-109	-	-	-	G	-	-	-	Domain of unknown function (DUF386)
HAPGPGAE_01895	2.58e-163	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HAPGPGAE_01896	1.15e-208	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HAPGPGAE_01897	6.97e-157	-	-	-	E	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01899	1.08e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HAPGPGAE_01900	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HAPGPGAE_01901	1.52e-37	-	-	-	-	-	-	-	-
HAPGPGAE_01902	3.24e-40	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HAPGPGAE_01903	2.88e-44	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
HAPGPGAE_01905	2.69e-149	-	-	-	S	-	-	-	Protein kinase domain
HAPGPGAE_01906	3.62e-79	-	-	-	S	-	-	-	von Willebrand factor (vWF) type A domain
HAPGPGAE_01907	6.86e-68	-	-	-	T	-	-	-	Protein phosphatase 2C
HAPGPGAE_01909	1.95e-36	-	-	-	S	-	-	-	MotA/TolQ/ExbB proton channel family
HAPGPGAE_01910	4.07e-88	-	-	-	N	-	-	-	OmpA family
HAPGPGAE_01912	5.68e-96	-	-	-	-	-	-	-	-
HAPGPGAE_01913	4.78e-160	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_01914	8.05e-168	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
HAPGPGAE_01915	8.06e-36	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HAPGPGAE_01916	4.91e-163	-	-	-	V	-	-	-	Abi-like protein
HAPGPGAE_01917	2.05e-19	-	-	-	-	-	-	-	-
HAPGPGAE_01918	2.35e-257	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGPGAE_01920	2.56e-07	-	-	-	D	-	-	-	MobA MobL family protein
HAPGPGAE_01921	2.67e-91	-	-	-	S	-	-	-	Domain of unknown function (DUF3846)
HAPGPGAE_01922	5.49e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
HAPGPGAE_01923	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Psort location Cytoplasmic, score
HAPGPGAE_01924	2.36e-38	-	-	-	S	-	-	-	Maff2 family
HAPGPGAE_01925	5.87e-196	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01926	1.73e-74	-	-	-	S	-	-	-	PrgI family protein
HAPGPGAE_01927	0.0	-	-	-	U	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01928	0.0	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HAPGPGAE_01930	1.16e-131	-	-	-	S	-	-	-	Domain of unknown function (DUF4366)
HAPGPGAE_01931	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	DNA topoisomerase III
HAPGPGAE_01932	4.05e-211	-	-	-	D	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_01933	1.78e-123	-	-	-	L	-	-	-	YodL-like
HAPGPGAE_01934	2.16e-39	-	-	-	S	-	-	-	Putative tranposon-transfer assisting protein
HAPGPGAE_01936	2.09e-75	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
HAPGPGAE_01938	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_01939	1.82e-62	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_01942	9.21e-304	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
HAPGPGAE_01943	3.47e-15	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HAPGPGAE_01944	2.33e-11	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_01945	1.64e-294	-	3.6.4.12	-	L	ko:K03658	-	ko00000,ko01000,ko03400	UvrD/REP helicase N-terminal domain
HAPGPGAE_01946	5e-37	-	-	-	-	-	-	-	-
HAPGPGAE_01947	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HAPGPGAE_01948	4.36e-103	-	-	-	-	-	-	-	-
HAPGPGAE_01953	4.03e-10	-	-	-	-	-	-	-	-
HAPGPGAE_01954	2.15e-136	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	citrate synthase
HAPGPGAE_01955	6.19e-101	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01956	1.35e-240	gap	1.2.1.12	-	C	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HAPGPGAE_01957	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAPGPGAE_01958	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAPGPGAE_01959	7.18e-233	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01960	2.33e-198	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, TatD family
HAPGPGAE_01961	6.59e-52	-	-	-	-	-	-	-	-
HAPGPGAE_01962	7.49e-64	-	-	-	S	-	-	-	Stress responsive A/B Barrel Domain
HAPGPGAE_01966	3.04e-100	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_01967	6.8e-151	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HAPGPGAE_01968	2.19e-38	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAPGPGAE_01969	2.61e-94	-	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HAPGPGAE_01970	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HAPGPGAE_01971	4.38e-209	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HAPGPGAE_01972	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HAPGPGAE_01973	4.73e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HAPGPGAE_01974	9.36e-171	-	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HAPGPGAE_01975	1.56e-176	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HAPGPGAE_01976	4.72e-212	bcrA_2	-	-	V	ko:K01990,ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HAPGPGAE_01977	2.04e-167	-	-	-	K	-	-	-	response regulator receiver
HAPGPGAE_01978	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPGPGAE_01979	6.73e-243	rluC	5.4.99.24	-	J	ko:K06179	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HAPGPGAE_01980	9.04e-171	radC	-	-	L	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HAPGPGAE_01981	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HAPGPGAE_01982	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HAPGPGAE_01984	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	phenylalanyl-tRNA synthetase (beta subunit)
HAPGPGAE_01985	6.28e-249	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HAPGPGAE_01986	2.92e-257	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HAPGPGAE_01988	4.69e-261	yqfD	-	-	M	ko:K06438	-	ko00000	Putative stage IV sporulation protein YqfD
HAPGPGAE_01989	9.63e-196	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HAPGPGAE_01990	7.18e-182	-	-	-	Q	-	-	-	Methyltransferase domain protein
HAPGPGAE_01991	1.72e-142	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HAPGPGAE_01992	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HAPGPGAE_01993	2.37e-117	-	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Psort location CytoplasmicMembrane, score
HAPGPGAE_01994	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HAPGPGAE_01995	6.86e-174	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_01997	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HAPGPGAE_01998	7.2e-130	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_01999	2.71e-72	-	-	-	-	-	-	-	-
HAPGPGAE_02000	7.41e-65	-	-	-	S	-	-	-	protein, YerC YecD
HAPGPGAE_02001	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Psort location CytoplasmicMembrane, score
HAPGPGAE_02002	6.62e-164	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HAPGPGAE_02003	2.13e-276	gcdB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	decarboxylase beta subunit
HAPGPGAE_02004	1.8e-59	-	-	-	C	-	-	-	decarboxylase gamma
HAPGPGAE_02005	9.51e-240	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein, MreB Mrl family
HAPGPGAE_02006	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HAPGPGAE_02007	3.16e-232	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_02008	3.89e-195	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HAPGPGAE_02013	1.76e-164	-	-	-	K	-	-	-	Helix-turn-helix
HAPGPGAE_02014	6.55e-65	-	-	-	S	-	-	-	regulation of response to stimulus
HAPGPGAE_02015	2.15e-166	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_02017	2.03e-250	-	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HAPGPGAE_02018	3.37e-273	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HAPGPGAE_02019	3.07e-119	ptbA	-	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HAPGPGAE_02020	6.09e-276	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HAPGPGAE_02021	0.0	nagE	2.7.1.193	-	G	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_02022	2.35e-127	mutX	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Psort location Cytoplasmic, score 8.96
HAPGPGAE_02023	1.62e-64	-	-	-	G	-	-	-	Ricin-type beta-trefoil
HAPGPGAE_02024	4.33e-116	nfrA2	-	-	C	-	-	-	Nitroreductase family
HAPGPGAE_02025	1.87e-117	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HAPGPGAE_02026	1.66e-61	-	-	-	S	-	-	-	Trp repressor protein
HAPGPGAE_02027	3.36e-118	yajL	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
HAPGPGAE_02028	1.04e-217	-	-	-	Q	-	-	-	FAH family
HAPGPGAE_02029	6.36e-231	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_02030	0.0	-	3.1.3.5, 3.6.1.45	-	F	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HAPGPGAE_02031	1.46e-156	-	-	-	S	-	-	-	IA, variant 3
HAPGPGAE_02032	2.76e-273	ilvE	2.6.1.42, 4.1.3.38	-	E	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HAPGPGAE_02033	7.51e-192	-	-	-	S	-	-	-	Putative esterase
HAPGPGAE_02034	1.16e-202	-	-	-	S	-	-	-	Putative esterase
HAPGPGAE_02035	6.08e-314	-	-	-	F	-	-	-	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HAPGPGAE_02036	2.84e-301	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_02037	1.11e-148	-	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotate phosphoribosyltransferase
HAPGPGAE_02038	8.52e-208	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0160)
HAPGPGAE_02039	3.49e-63	-	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HAPGPGAE_02042	2.59e-106	-	-	-	S	-	-	-	RNHCP domain
HAPGPGAE_02043	3.06e-187	yoaP	-	-	E	-	-	-	YoaP-like
HAPGPGAE_02044	6.86e-126	-	-	-	K	-	-	-	Acetyltransferase GNAT family
HAPGPGAE_02045	3.54e-186	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HAPGPGAE_02046	0.0	-	-	-	T	-	-	-	Response regulator receiver domain protein
HAPGPGAE_02047	7.54e-199	-	-	-	S	-	-	-	Protein of unknown function (DUF2961)
HAPGPGAE_02048	1.34e-34	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02049	2.43e-37	-	-	-	S	-	-	-	Replication initiator protein A domain protein
HAPGPGAE_02050	0.0	-	-	-	S	-	-	-	alpha beta
HAPGPGAE_02051	2.43e-239	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPGPGAE_02052	8.13e-61	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HAPGPGAE_02053	1.06e-195	-	-	-	S	-	-	-	Replication initiator protein A domain protein
HAPGPGAE_02054	2.12e-188	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HAPGPGAE_02055	1.11e-202	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HAPGPGAE_02058	1.86e-98	-	-	-	S	-	-	-	DpnD/PcfM-like protein
HAPGPGAE_02059	3.05e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
HAPGPGAE_02060	8.84e-228	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Psort location Cytoplasmic, score
HAPGPGAE_02061	0.0	-	-	-	L	-	-	-	Domain of unknown function (DUF4368)
HAPGPGAE_02062	2.06e-78	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
HAPGPGAE_02063	3.72e-68	-	-	-	-	-	-	-	-
HAPGPGAE_02064	1.94e-83	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02065	9.85e-33	-	-	-	K	-	-	-	trisaccharide binding
HAPGPGAE_02066	1.02e-97	-	-	-	K	-	-	-	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAPGPGAE_02067	3.9e-89	-	-	-	T	-	-	-	Histidine kinase
HAPGPGAE_02068	2.93e-115	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HAPGPGAE_02069	1.42e-68	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HAPGPGAE_02071	3.07e-233	nifJ	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HAPGPGAE_02072	5.71e-58	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HAPGPGAE_02073	5.01e-80	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HAPGPGAE_02074	0.0	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HAPGPGAE_02076	1.28e-144	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_02077	3.95e-206	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
HAPGPGAE_02078	1.51e-72	PaaY	-	-	S	ko:K02617	-	ko00000	Bacterial transferase hexapeptide repeat protein
HAPGPGAE_02079	2.5e-296	-	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HAPGPGAE_02080	4.33e-186	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	biotin acetyl-CoA-carboxylase ligase
HAPGPGAE_02081	7.79e-80	yfcE1	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HAPGPGAE_02082	1.68e-192	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HAPGPGAE_02083	3.26e-156	yfiC	2.1.1.223	-	S	ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HAPGPGAE_02084	8.06e-17	-	-	-	C	-	-	-	4Fe-4S binding domain
HAPGPGAE_02085	5.64e-227	yaaT	-	-	S	-	-	-	PSP1 C-terminal domain protein
HAPGPGAE_02086	0.0	czcA	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAPGPGAE_02087	1.26e-268	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HAPGPGAE_02088	3.55e-260	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP-glucose 4-epimerase
HAPGPGAE_02089	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HAPGPGAE_02090	1.09e-95	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HAPGPGAE_02091	2.87e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HAPGPGAE_02092	9.99e-305	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HAPGPGAE_02093	1.01e-156	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HAPGPGAE_02094	1.37e-157	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HAPGPGAE_02097	2.93e-159	cpsE	-	-	M	-	-	-	sugar transferase
HAPGPGAE_02098	0.0	ilvD	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HAPGPGAE_02099	1.31e-245	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HAPGPGAE_02100	1.48e-123	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetolactate synthase small
HAPGPGAE_02101	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	acetolactate synthase large subunit
HAPGPGAE_02102	3.34e-286	-	-	-	S	ko:K06923	-	ko00000	ATPase (AAA superfamily)
HAPGPGAE_02103	8.49e-79	-	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
HAPGPGAE_02104	1.35e-283	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HAPGPGAE_02105	1.04e-82	-	-	-	S	ko:K06872	-	ko00000	Pfam:TPM
HAPGPGAE_02106	6.21e-164	-	-	-	-	-	-	-	-
HAPGPGAE_02107	2.03e-253	-	-	-	P	-	-	-	Belongs to the TelA family
HAPGPGAE_02108	1.56e-138	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HAPGPGAE_02109	7.66e-116	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	UreE urease accessory protein, C-terminal domain
HAPGPGAE_02110	1.8e-220	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HAPGPGAE_02111	1.2e-203	-	-	-	S	ko:K07089	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_02112	6.64e-186	thiF	-	-	H	ko:K22132	-	ko00000,ko03016	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HAPGPGAE_02113	1.73e-271	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HAPGPGAE_02114	3.68e-312	cca	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	tRNA nucleotidyltransferase poly(A) polymerase
HAPGPGAE_02115	6.82e-223	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HAPGPGAE_02117	1.96e-206	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HAPGPGAE_02118	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HAPGPGAE_02119	2.16e-210	-	-	-	K	-	-	-	LysR substrate binding domain protein
HAPGPGAE_02120	4.65e-185	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_02121	3.31e-84	-	-	-	L	-	-	-	Dinitrogenase iron-molybdenum cofactor
HAPGPGAE_02122	1.33e-224	-	-	-	G	-	-	-	Aldose 1-epimerase
HAPGPGAE_02124	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	SAF domain protein
HAPGPGAE_02125	3.37e-87	-	1.1.1.17, 1.1.1.58	-	C	ko:K00009,ko:K00041	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase
HAPGPGAE_02126	1.43e-306	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	xanthine uracil permease family protein K06901
HAPGPGAE_02127	0.0	-	-	-	S	ko:K06972	-	ko00000,ko01000,ko01002	Peptidase M16C associated
HAPGPGAE_02129	1.59e-222	mglC	-	-	G	ko:K10541	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_02130	0.0	mglA	3.6.3.17	-	G	ko:K10542	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC-type sugar transport system, ATPase component
HAPGPGAE_02131	1.88e-230	-	-	-	G	ko:K10540	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG COG1879 ABC-type sugar transport system, periplasmic component
HAPGPGAE_02133	0.0	-	-	-	S	-	-	-	Terminase-like family
HAPGPGAE_02134	0.0	-	-	-	-	-	-	-	-
HAPGPGAE_02135	3.78e-131	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HAPGPGAE_02136	6.7e-240	-	-	-	-	-	-	-	-
HAPGPGAE_02139	0.0	-	-	-	-	-	-	-	-
HAPGPGAE_02141	6.72e-234	-	-	-	-	-	-	-	-
HAPGPGAE_02144	4.9e-83	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_02145	1.74e-140	-	-	-	S	-	-	-	Protein of unknown function (DUF1643)
HAPGPGAE_02146	0.0	-	-	-	S	-	-	-	ABC transporter substrate-binding protein PnrA-like
HAPGPGAE_02147	6.09e-128	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HAPGPGAE_02148	9.17e-44	-	-	-	-	-	-	-	-
HAPGPGAE_02149	0.0	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
HAPGPGAE_02150	5.71e-32	-	-	-	-	-	-	-	-
HAPGPGAE_02151	3e-271	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGPGAE_02152	1.43e-161	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Universal bacterial protein YeaZ
HAPGPGAE_02153	8.69e-96	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HAPGPGAE_02154	8.76e-281	-	-	-	-	-	-	-	-
HAPGPGAE_02155	1.72e-278	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HAPGPGAE_02156	1.31e-134	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HAPGPGAE_02157	6.76e-170	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPGPGAE_02158	7.25e-213	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HAPGPGAE_02159	9.53e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HAPGPGAE_02160	2.67e-192	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_02161	3.83e-231	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HAPGPGAE_02162	0.0	-	-	-	G	-	-	-	ABC-type sugar transport system periplasmic component
HAPGPGAE_02163	2.53e-241	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	sugar-binding domain protein
HAPGPGAE_02164	0.0	-	2.4.1.20	GT36	G	ko:K00702	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyltransferase family 36
HAPGPGAE_02165	6.18e-115	thiW	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_02166	4.27e-186	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HAPGPGAE_02167	6.92e-148	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HAPGPGAE_02168	1.72e-315	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HAPGPGAE_02169	3.34e-280	-	-	-	E	ko:K03310	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_02170	0.0	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_02171	1.07e-172	yacO	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAPGPGAE_02172	9.93e-208	fba	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HAPGPGAE_02173	7.2e-166	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
HAPGPGAE_02176	1.91e-135	KatE	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02177	0.0	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase, group 2 family protein
HAPGPGAE_02178	5.44e-176	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HAPGPGAE_02179	1.97e-186	pyrL	-	-	GM	ko:K01992,ko:K09690	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HAPGPGAE_02180	5.62e-142	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HAPGPGAE_02181	1.39e-311	dacB_3	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HAPGPGAE_02182	7.84e-133	spoVFB	-	-	H	ko:K06411	-	ko00000	Dipicolinic acid synthetase, B subunit
HAPGPGAE_02183	1.98e-166	spoVFA	-	-	EH	ko:K06410	-	ko00000	dipicolinic acid synthetase, A subunit
HAPGPGAE_02184	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HAPGPGAE_02185	1.37e-130	fliY1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HAPGPGAE_02186	7.41e-203	-	-	-	T	ko:K07814	-	ko00000,ko02022	Response regulator containing a CheY-like receiver domain and an HD-GYP domain
HAPGPGAE_02187	6.07e-223	-	-	-	T	ko:K07814	-	ko00000,ko02022	Response regulator containing a CheY-like receiver domain and an HD-GYP domain
HAPGPGAE_02189	3.61e-304	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HAPGPGAE_02190	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_02191	4.43e-258	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type branched-chain amino acid transport systems periplasmic component
HAPGPGAE_02192	3.12e-193	livH	-	-	E	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HAPGPGAE_02193	1.43e-230	livM	-	-	E	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HAPGPGAE_02194	4.52e-200	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type branched-chain amino acid transport systems ATPase component
HAPGPGAE_02195	5.4e-162	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HAPGPGAE_02196	8.96e-252	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate-ammonia ligase
HAPGPGAE_02197	1e-218	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HAPGPGAE_02198	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HAPGPGAE_02199	1.13e-181	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HAPGPGAE_02200	2.05e-165	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HAPGPGAE_02201	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HAPGPGAE_02202	1.1e-310	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HAPGPGAE_02203	4.69e-06	safA	-	-	V	-	-	-	Cysteine-rich secretory protein family
HAPGPGAE_02204	1.7e-203	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HAPGPGAE_02205	8.26e-231	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
HAPGPGAE_02206	5.98e-64	yidD	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HAPGPGAE_02207	4.55e-86	rnpA	3.1.26.5	-	J	ko:K03536,ko:K08998	-	ko00000,ko01000,ko03016	ribonuclease P activity
HAPGPGAE_02208	4.78e-22	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HAPGPGAE_02209	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HAPGPGAE_02210	2.94e-169	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HAPGPGAE_02211	7.54e-44	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein
HAPGPGAE_02212	4.36e-260	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAPGPGAE_02213	1.47e-54	-	-	-	S	-	-	-	Domain of unknown function (DUF370)
HAPGPGAE_02215	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAPGPGAE_02216	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAPGPGAE_02217	2.43e-125	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HAPGPGAE_02218	1.82e-160	-	-	-	K	ko:K22293	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
HAPGPGAE_02219	2.47e-134	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Pseudouridine synthase
HAPGPGAE_02220	1.09e-128	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_02222	3.99e-53	-	-	-	-	-	-	-	-
HAPGPGAE_02223	3.89e-210	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HAPGPGAE_02224	8.11e-145	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HAPGPGAE_02225	1.9e-232	-	-	-	M	-	-	-	SIS domain
HAPGPGAE_02226	1.61e-188	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HAPGPGAE_02227	1.71e-174	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HAPGPGAE_02228	1.51e-105	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HAPGPGAE_02229	5.38e-79	-	2.7.1.191	-	G	ko:K02793,ko:K19506	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HAPGPGAE_02230	4.78e-163	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	PFAM Bacterial regulatory proteins, gntR family
HAPGPGAE_02231	6.41e-183	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02232	1.2e-138	-	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	DNA primase activity
HAPGPGAE_02233	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4 family
HAPGPGAE_02234	4.25e-223	-	-	-	D	-	-	-	Plasmid recombination enzyme
HAPGPGAE_02235	6.58e-60	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPGPGAE_02236	0.0	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGPGAE_02237	2.91e-55	-	-	-	-	-	-	-	-
HAPGPGAE_02238	7.71e-296	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score
HAPGPGAE_02239	0.0	-	-	-	-	-	-	-	-
HAPGPGAE_02240	1.68e-165	-	-	-	S	-	-	-	Protein of unknown function (Hypoth_ymh)
HAPGPGAE_02241	0.0	-	3.1.21.5	-	KL	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
HAPGPGAE_02242	0.0	mod	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	PFAM DNA methylase
HAPGPGAE_02243	3.61e-42	-	-	-	K	-	-	-	trisaccharide binding
HAPGPGAE_02244	4.96e-172	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HAPGPGAE_02245	7.9e-288	pgk	2.7.2.3, 5.3.1.1	-	G	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HAPGPGAE_02246	2.13e-227	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HAPGPGAE_02247	1.91e-204	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HAPGPGAE_02248	5.45e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
HAPGPGAE_02249	1.81e-85	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HAPGPGAE_02250	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HAPGPGAE_02251	5.95e-84	-	-	-	J	-	-	-	ribosomal protein
HAPGPGAE_02252	3.45e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Psort location Cytoplasmic, score 8.96
HAPGPGAE_02253	2.06e-259	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HAPGPGAE_02254	5.61e-113	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HAPGPGAE_02255	4.2e-268	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
HAPGPGAE_02256	0.0	agcS_2	-	-	E	ko:K03310	-	ko00000	amino acid carrier protein
HAPGPGAE_02257	6.38e-297	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_02258	1.5e-129	yfcE	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HAPGPGAE_02259	1.31e-218	-	2.7.1.40	-	H	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
HAPGPGAE_02260	1.41e-214	-	2.7.1.15, 2.7.1.83	-	H	ko:K00852,ko:K16328	ko00030,ko00240,map00030,map00240	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_02261	3.02e-256	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_02263	2.01e-183	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPGPGAE_02264	1.77e-26	nagE	2.7.1.193	-	G	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_02266	1.01e-127	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HAPGPGAE_02267	7.39e-188	agaD	-	-	G	ko:K02747	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_02268	1.52e-174	agaC	-	-	G	ko:K02746	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HAPGPGAE_02269	2.68e-105	-	2.7.1.191	-	G	ko:K02745,ko:K02794	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HAPGPGAE_02270	8.14e-252	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HAPGPGAE_02271	2.81e-139	-	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase NAD-binding domain protein
HAPGPGAE_02272	2.12e-191	-	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG COG0191 Fructose tagatose bisphosphate aldolase
HAPGPGAE_02273	6.34e-49	-	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase, YajC subunit
HAPGPGAE_02274	3.6e-91	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HAPGPGAE_02275	1.09e-273	agaS	2.6.1.16	-	M	ko:K00820,ko:K02082	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	sugar isomerase, AgaS family
HAPGPGAE_02276	9.38e-257	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HAPGPGAE_02277	3.35e-305	-	-	-	G	ko:K16371	ko00052,ko01100,map00052,map01100	ko00000,ko00001	Tagatose 6 phosphate kinase
HAPGPGAE_02278	6.8e-42	-	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier, HPr family
HAPGPGAE_02281	6.59e-69	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HAPGPGAE_02282	2.06e-17	-	-	-	-	-	-	-	-
HAPGPGAE_02283	8.85e-11	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HAPGPGAE_02284	1.4e-47	-	-	-	K	-	-	-	PFAM helix-turn-helix domain protein
HAPGPGAE_02286	2.01e-166	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02287	2.51e-198	-	-	-	K	-	-	-	DNA binding
HAPGPGAE_02288	1.44e-65	-	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HAPGPGAE_02289	5.04e-47	-	-	-	S	-	-	-	DNA binding domain, excisionase family
HAPGPGAE_02290	3.15e-277	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGPGAE_02292	2.58e-98	-	-	-	K	-	-	-	Transcriptional regulator
HAPGPGAE_02293	0.0	bcd2	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	Rubredoxin
HAPGPGAE_02294	7.75e-300	fprA2	-	-	C	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02295	0.0	nrdA	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HAPGPGAE_02296	6.91e-261	nrdB	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAPGPGAE_02297	1.16e-206	-	-	-	C	-	-	-	Putative TM nitroreductase
HAPGPGAE_02298	1.64e-68	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin
HAPGPGAE_02299	2.89e-202	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HAPGPGAE_02300	5.11e-104	-	-	-	K	-	-	-	Cyclic nucleotide-monophosphate binding domain
HAPGPGAE_02301	5.64e-27	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2249)
HAPGPGAE_02302	2.25e-127	-	-	-	-	-	-	-	-
HAPGPGAE_02303	4.81e-257	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02304	8.57e-35	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAPGPGAE_02305	5.53e-110	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HAPGPGAE_02306	7.79e-93	-	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
HAPGPGAE_02307	4.83e-108	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HAPGPGAE_02308	5.39e-293	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HAPGPGAE_02309	9.15e-141	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin synthase, alpha subunit
HAPGPGAE_02310	2.39e-277	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HAPGPGAE_02311	1.13e-58	-	-	-	P	-	-	-	Rhodanese Homology Domain
HAPGPGAE_02312	0.0	-	-	-	L	-	-	-	helicase C-terminal domain protein
HAPGPGAE_02313	2.99e-85	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HAPGPGAE_02315	1.14e-225	-	-	-	S	-	-	-	Domain of unknown function (DUF932)
HAPGPGAE_02317	1.13e-220	-	-	-	L	-	-	-	YqaJ viral recombinase family
HAPGPGAE_02318	1.79e-287	-	-	-	S	ko:K07133	-	ko00000	Psort location Cytoplasmic, score
HAPGPGAE_02319	2.01e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF1071)
HAPGPGAE_02320	0.0	-	-	-	S	-	-	-	Predicted AAA-ATPase
HAPGPGAE_02321	1.54e-80	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02322	1.02e-34	-	3.6.4.12	-	S	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	double-stranded DNA endodeoxyribonuclease activity
HAPGPGAE_02323	4.42e-73	-	-	-	L	-	-	-	Domain of unknown function (DUF3846)
HAPGPGAE_02324	4.38e-76	-	-	-	-	-	-	-	-
HAPGPGAE_02325	2.3e-172	-	-	-	L	-	-	-	Resolvase, N terminal domain
HAPGPGAE_02330	0.0	-	-	-	T	ko:K06883	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HAPGPGAE_02332	6.96e-239	-	-	-	K	-	-	-	WYL domain
HAPGPGAE_02333	5.56e-72	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAPGPGAE_02334	5.97e-29	-	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Peptidase family M41
HAPGPGAE_02335	1.35e-07	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
HAPGPGAE_02336	4.87e-244	-	-	-	P	-	-	-	Citrate transporter
HAPGPGAE_02337	2.11e-200	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HAPGPGAE_02338	1.26e-315	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HAPGPGAE_02339	3.09e-212	-	-	-	K	-	-	-	LysR substrate binding domain protein
HAPGPGAE_02340	3.05e-234	-	-	-	G	-	-	-	TRAP transporter solute receptor, DctP family
HAPGPGAE_02341	1.9e-281	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_02342	9.27e-121	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_02343	6.99e-245	-	-	-	G	-	-	-	TRAP transporter solute receptor, DctP family
HAPGPGAE_02344	2.03e-179	-	-	-	K	-	-	-	Response regulator receiver domain
HAPGPGAE_02345	0.0	-	-	-	T	-	-	-	Histidine kinase
HAPGPGAE_02346	6.9e-157	-	-	-	K	-	-	-	Cyclic nucleotide-binding domain protein
HAPGPGAE_02347	3.1e-158	-	-	-	C	-	-	-	4Fe-4S binding domain protein
HAPGPGAE_02348	0.0	-	-	-	T	-	-	-	Response regulator receiver domain protein
HAPGPGAE_02350	0.0	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HAPGPGAE_02351	1.04e-292	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT IMPCHase bienzyme
HAPGPGAE_02352	8.08e-192	-	-	-	F	-	-	-	IMP cyclohydrolase-like protein
HAPGPGAE_02353	4.02e-131	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HAPGPGAE_02354	2.4e-257	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HAPGPGAE_02355	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HAPGPGAE_02356	3.31e-103	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HAPGPGAE_02357	3.25e-107	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HAPGPGAE_02358	1.31e-244	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	synthase
HAPGPGAE_02359	1.56e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3783)
HAPGPGAE_02360	1.68e-254	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HAPGPGAE_02361	3.34e-185	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HAPGPGAE_02362	4.24e-37	-	-	-	S	-	-	-	Transposon-encoded protein TnpW
HAPGPGAE_02363	0.0	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
HAPGPGAE_02364	0.0	-	-	-	D	-	-	-	MobA MobL family protein
HAPGPGAE_02365	2.07e-16	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02366	2.12e-34	-	-	-	-	-	-	-	-
HAPGPGAE_02367	6.7e-296	-	-	-	L	-	-	-	T/G mismatch-specific endonuclease activity
HAPGPGAE_02368	3.42e-145	-	-	-	-	-	-	-	-
HAPGPGAE_02369	1.1e-131	-	-	-	-	-	-	-	-
HAPGPGAE_02370	3.34e-275	dcm	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	PFAM C-5 cytosine-specific DNA methylase
HAPGPGAE_02374	1.46e-47	-	-	-	-	-	-	-	-
HAPGPGAE_02375	9.32e-74	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
HAPGPGAE_02376	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02377	8.66e-95	-	-	-	KL	-	-	-	SNF2 family N-terminal domain
HAPGPGAE_02378	2.05e-38	ynzC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF896)
HAPGPGAE_02379	1.36e-151	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HAPGPGAE_02380	4.97e-252	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HAPGPGAE_02381	3.72e-283	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
HAPGPGAE_02382	7.32e-46	-	-	-	IQ	ko:K02078	-	ko00000,ko00001	Acyl carrier protein
HAPGPGAE_02383	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Psort location Cytoplasmic, score
HAPGPGAE_02384	1.05e-274	-	-	-	G	-	-	-	Acyltransferase family
HAPGPGAE_02386	0.0	-	-	-	M	-	-	-	Glycosyl-transferase family 4
HAPGPGAE_02387	5.29e-239	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HAPGPGAE_02389	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	TIGRFAM formate acetyltransferase
HAPGPGAE_02391	1.77e-238	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
HAPGPGAE_02392	4.69e-161	-	-	-	-	-	-	-	-
HAPGPGAE_02393	2.72e-14	-	-	-	E	-	-	-	Parallel beta-helix repeats
HAPGPGAE_02394	4.46e-193	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HAPGPGAE_02395	9.32e-280	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HAPGPGAE_02397	7.52e-179	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HAPGPGAE_02398	1.51e-205	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HAPGPGAE_02399	5.63e-177	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HAPGPGAE_02400	7.73e-256	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Psort location Cytoplasmic, score
HAPGPGAE_02401	1.44e-164	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HAPGPGAE_02402	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HAPGPGAE_02403	5.33e-109	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphoribosylformylglycinamidine synthase
HAPGPGAE_02404	7.33e-62	-	-	-	S	-	-	-	Putative redox-active protein (C_GCAxxG_C_C)
HAPGPGAE_02405	2.35e-106	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HAPGPGAE_02406	1.26e-112	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_02407	8.49e-157	-	-	-	S	-	-	-	Domain of unknown function (DUF5058)
HAPGPGAE_02408	6.22e-163	-	-	-	-	-	-	-	-
HAPGPGAE_02409	2.16e-204	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HAPGPGAE_02411	5.59e-271	fucO	1.1.1.77	-	C	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HAPGPGAE_02412	3.82e-316	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_02413	3.1e-202	-	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger family protein
HAPGPGAE_02414	0.0	-	-	-	C	-	-	-	NADH oxidase
HAPGPGAE_02415	1.06e-184	aroD	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HAPGPGAE_02416	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HAPGPGAE_02419	1.89e-86	-	-	-	S	-	-	-	Uncharacterised nucleotidyltransferase
HAPGPGAE_02421	1.43e-199	-	-	-	V	-	-	-	ABC transporter
HAPGPGAE_02422	5.56e-67	-	-	-	U	-	-	-	Belongs to the peptidase S26 family
HAPGPGAE_02425	4.93e-19	-	-	-	C	-	-	-	radical SAM
HAPGPGAE_02426	2.81e-34	-	-	-	C	-	-	-	radical SAM
HAPGPGAE_02427	1.66e-94	-	-	-	-	-	-	-	-
HAPGPGAE_02429	5.13e-22	-	-	-	T	-	-	-	diguanylate cyclase
HAPGPGAE_02430	1.92e-16	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02431	0.0	-	-	-	D	-	-	-	MobA MobL family protein
HAPGPGAE_02432	0.0	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
HAPGPGAE_02433	2.94e-23	-	-	-	S	-	-	-	Transposon-encoded protein TnpW
HAPGPGAE_02434	1.86e-88	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HAPGPGAE_02436	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02438	0.0	-	-	-	D	-	-	-	MobA MobL family protein
HAPGPGAE_02439	2.38e-17	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02440	1.2e-283	-	-	-	T	-	-	-	GHKL domain
HAPGPGAE_02441	1.28e-162	-	-	-	K	-	-	-	LytTr DNA-binding domain
HAPGPGAE_02442	2.94e-108	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide
HAPGPGAE_02444	8.72e-24	-	-	-	-	-	-	-	-
HAPGPGAE_02446	4.47e-13	-	-	-	-	-	-	-	-
HAPGPGAE_02448	0.0	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGPGAE_02449	5.16e-57	-	-	-	L	-	-	-	Helix-turn-helix domain
HAPGPGAE_02450	9.94e-271	-	-	-	D	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02451	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4 family
HAPGPGAE_02452	4.48e-133	-	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	DNA primase activity
HAPGPGAE_02453	5.39e-186	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HAPGPGAE_02454	3.15e-153	-	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma-70 region 2
HAPGPGAE_02455	1.02e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HAPGPGAE_02456	4.05e-112	-	-	-	M	-	-	-	Domain of unknown function (DUF4367)
HAPGPGAE_02457	1.63e-132	-	-	-	-	-	-	-	-
HAPGPGAE_02459	3.27e-123	-	-	-	-	-	-	-	-
HAPGPGAE_02460	6.39e-50	-	-	-	-	-	-	-	-
HAPGPGAE_02462	1.51e-51	-	-	-	-	-	-	-	-
HAPGPGAE_02463	8.16e-207	-	-	-	S	-	-	-	TraX protein
HAPGPGAE_02464	3.96e-154	-	-	-	KT	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HAPGPGAE_02465	3.3e-211	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HAPGPGAE_02466	5.24e-231	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
HAPGPGAE_02467	2.58e-54	-	-	-	K	ko:K06284	-	ko00000,ko03000	Transcriptional regulator, AbrB family
HAPGPGAE_02468	9.09e-282	-	-	-	P	-	-	-	Transporter, CPA2 family
HAPGPGAE_02469	9.72e-254	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HAPGPGAE_02470	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HAPGPGAE_02471	6.34e-142	nrdG	1.97.1.4	-	C	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HAPGPGAE_02472	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HAPGPGAE_02473	1.04e-199	-	-	-	U	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_02474	2.12e-195	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_02476	2.05e-51	-	-	-	-	-	-	-	-
HAPGPGAE_02478	6.45e-70	-	-	-	T	-	-	-	Hpt domain
HAPGPGAE_02479	2.92e-233	-	1.1.1.79, 1.1.1.81	-	EH	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HAPGPGAE_02480	7.35e-71	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
HAPGPGAE_02481	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glutaminyl-tRNA synthetase
HAPGPGAE_02482	4.7e-205	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_02483	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HAPGPGAE_02485	1.3e-156	-	-	-	S	-	-	-	hydrolase of the alpha beta superfamily
HAPGPGAE_02486	7.18e-145	-	-	-	S	-	-	-	YheO-like PAS domain
HAPGPGAE_02487	2.17e-81	TdcF	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
HAPGPGAE_02488	3.31e-301	-	-	-	S	-	-	-	Belongs to the UPF0597 family
HAPGPGAE_02489	4.28e-274	-	-	-	C	-	-	-	Sodium:dicarboxylate symporter family
HAPGPGAE_02490	3.41e-278	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HAPGPGAE_02491	4.08e-291	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	PFAM Aminotransferase class I and II
HAPGPGAE_02492	2.22e-299	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
HAPGPGAE_02494	2.12e-175	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HAPGPGAE_02496	6.33e-83	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4 family
HAPGPGAE_02497	2.46e-15	-	-	-	K	-	-	-	Helix-turn-helix domain
HAPGPGAE_02498	2.08e-303	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGPGAE_02501	0.0	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
HAPGPGAE_02502	2.99e-312	hsdM	2.1.1.72	-	L	ko:K03427	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HAPGPGAE_02503	2.71e-198	-	-	-	S	-	-	-	Psort location
HAPGPGAE_02504	7.08e-166	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_02505	1.15e-120	-	-	-	-	-	-	-	-
HAPGPGAE_02506	4.02e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HAPGPGAE_02507	1.1e-184	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HAPGPGAE_02508	6.23e-192	rnfB	-	-	C	ko:K03616	-	ko00000	electron transport complex, RnfABCDGE type, B subunit
HAPGPGAE_02509	3.97e-137	rnfA	-	-	C	ko:K03617	-	ko00000	Part of a membrane complex involved in electron transport
HAPGPGAE_02510	1.23e-150	rnfE	-	-	C	ko:K03613	-	ko00000	Part of a membrane complex involved in electron transport
HAPGPGAE_02511	1.54e-119	rnfG	-	-	C	ko:K03612	-	ko00000	Part of a membrane complex involved in electron transport
HAPGPGAE_02512	1.47e-216	rnfD	-	-	C	ko:K03614	-	ko00000	Part of a membrane complex involved in electron transport
HAPGPGAE_02513	3.37e-311	rnfC	-	-	C	ko:K03615	-	ko00000	Part of a membrane complex involved in electron transport
HAPGPGAE_02514	4.24e-292	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
HAPGPGAE_02517	1.68e-67	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_02518	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_02519	3.09e-22	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
HAPGPGAE_02520	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HAPGPGAE_02521	1.02e-169	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HAPGPGAE_02522	0.0	-	-	CE1	Q	ko:K03932	-	ko00000	Esterase PHB depolymerase
HAPGPGAE_02523	6.34e-276	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribose-phosphate pyrophosphokinase family
HAPGPGAE_02524	2.58e-54	-	-	-	-	-	-	-	-
HAPGPGAE_02525	2.31e-248	-	-	-	K	-	-	-	AraC-like ligand binding domain
HAPGPGAE_02526	0.0	-	-	-	G	ko:K03292	-	ko00000	Transporter, major facilitator family protein
HAPGPGAE_02527	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HAPGPGAE_02528	7.84e-175	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_02529	8.41e-281	-	-	-	T	-	-	-	diguanylate cyclase
HAPGPGAE_02530	5.68e-156	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HAPGPGAE_02532	8.49e-125	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_02533	2.52e-246	ispH	1.17.7.4	-	IJM	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HAPGPGAE_02534	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport system periplasmic component
HAPGPGAE_02535	3.5e-206	-	-	-	P	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport system, permease component
HAPGPGAE_02536	2.88e-221	-	-	-	P	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate ABC transporter membrane protein 1 CUT1 family
HAPGPGAE_02537	5.4e-93	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score
HAPGPGAE_02538	1.5e-144	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HAPGPGAE_02539	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HAPGPGAE_02540	9.89e-173	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	EcoEI R protein C-terminal
HAPGPGAE_02541	4.28e-97	-	-	-	K	-	-	-	Sigma-70, region 4
HAPGPGAE_02542	7.5e-53	-	-	-	S	-	-	-	Helix-turn-helix domain
HAPGPGAE_02543	5.59e-08	-	-	-	-	-	-	-	-
HAPGPGAE_02544	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02546	9.73e-180	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HAPGPGAE_02547	7.68e-40	-	-	-	U	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02548	0.0	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HAPGPGAE_02549	0.0	ltrA	-	-	L	-	-	-	Reverse transcriptase
HAPGPGAE_02550	5.84e-124	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HAPGPGAE_02551	1.96e-137	-	-	-	-	-	-	-	-
HAPGPGAE_02552	4.96e-126	-	-	-	-	-	-	-	-
HAPGPGAE_02553	2.67e-113	-	-	-	-	-	-	-	-
HAPGPGAE_02554	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02555	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC-type multidrug transport system ATPase and permease
HAPGPGAE_02556	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HAPGPGAE_02557	6.13e-50	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HAPGPGAE_02558	0.0	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HAPGPGAE_02560	1.97e-136	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HAPGPGAE_02561	2.71e-207	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HAPGPGAE_02562	2.08e-158	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HAPGPGAE_02563	1.1e-200	-	-	-	S	-	-	-	Replication initiator protein A
HAPGPGAE_02564	8.47e-152	-	-	-	-	-	-	-	-
HAPGPGAE_02565	3.06e-179	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HAPGPGAE_02566	6.84e-82	niaR	-	-	K	ko:K07105	-	ko00000	Psort location Cytoplasmic, score 8.87
HAPGPGAE_02567	1.27e-143	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HAPGPGAE_02568	7.93e-205	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HAPGPGAE_02569	1.91e-71	-	-	-	S	-	-	-	LURP-one-related
HAPGPGAE_02570	2.78e-82	-	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
HAPGPGAE_02571	2.27e-09	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HAPGPGAE_02572	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system DNA methylase K03427
HAPGPGAE_02573	2.65e-140	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
HAPGPGAE_02574	2.42e-126	-	-	-	P	ko:K07240	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HAPGPGAE_02575	1.04e-123	-	-	-	P	ko:K07240	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HAPGPGAE_02576	3.07e-197	-	-	-	U	-	-	-	Psort location Cytoplasmic, score
HAPGPGAE_02577	0.0	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HAPGPGAE_02579	6.96e-111	-	-	-	KL	-	-	-	CHC2 zinc finger
HAPGPGAE_02581	2.04e-177	-	-	-	U	-	-	-	Psort location Cytoplasmic, score 8.96
HAPGPGAE_02582	1.05e-93	-	-	-	-	-	-	-	-
HAPGPGAE_02583	7.25e-304	rhaB	2.7.1.5	-	H	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Carbohydrate kinase, FGGY family protein
HAPGPGAE_02584	1.21e-68	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HAPGPGAE_02585	4.53e-61	-	-	-	S	-	-	-	PrgI family protein
HAPGPGAE_02586	2.1e-211	-	-	-	U	-	-	-	Psort location Cytoplasmic, score