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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HOFPAOPE_00007	1.06e-202	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Bacterial DNA topoisomeraes I ATP-binding domain
HOFPAOPE_00008	0.000131	-	-	-	S	-	-	-	Domain of unknown function (DUF4366)
HOFPAOPE_00010	7.06e-46	-	-	-	-	-	-	-	-
HOFPAOPE_00011	0.0	-	-	-	U	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_00012	2.43e-32	-	-	-	S	-	-	-	PrgI family protein
HOFPAOPE_00013	3.08e-85	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_00014	1.48e-28	-	-	-	S	-	-	-	Maff2 family
HOFPAOPE_00015	3.08e-274	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Psort location Cytoplasmic, score
HOFPAOPE_00016	5.34e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
HOFPAOPE_00018	1.81e-44	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
HOFPAOPE_00020	6.47e-59	-	-	-	F	-	-	-	NUDIX domain
HOFPAOPE_00021	3.64e-66	-	-	-	S	-	-	-	AAA domain
HOFPAOPE_00022	2.2e-279	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HOFPAOPE_00023	2.94e-259	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HOFPAOPE_00024	6.6e-279	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HOFPAOPE_00025	1.1e-248	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HOFPAOPE_00026	2.84e-133	purC	4.3.2.2, 6.3.2.6	-	F	ko:K01756,ko:K01923	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HOFPAOPE_00027	1.65e-07	-	-	-	S	-	-	-	Short C-terminal domain
HOFPAOPE_00030	8.07e-26	-	-	-	S	ko:K07052	-	ko00000	Psort location CytoplasmicMembrane, score
HOFPAOPE_00031	1.72e-66	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HOFPAOPE_00032	5.5e-205	ynbB	-	-	P	-	-	-	Cystathionine beta-lyase family protein involved in aluminum resistance
HOFPAOPE_00034	1.29e-115	cel	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	aminopeptidase activity
HOFPAOPE_00035	1.15e-93	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HOFPAOPE_00036	1.15e-218	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HOFPAOPE_00037	2.38e-108	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	transaminase activity
HOFPAOPE_00038	8.34e-69	-	-	-	-	-	-	-	-
HOFPAOPE_00039	6.87e-53	-	3.4.16.4	-	V	ko:K01286	-	ko00000,ko01000	beta-lactamase
HOFPAOPE_00040	1.28e-312	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HOFPAOPE_00043	9.41e-92	-	-	-	L	ko:K02315,ko:K07452	-	ko00000,ko01000,ko02048,ko03032	DNA-dependent DNA replication
HOFPAOPE_00044	5.04e-73	dnaD	-	-	L	-	-	-	DnaD domain protein
HOFPAOPE_00045	8.96e-33	-	-	-	S	-	-	-	TSCPD domain
HOFPAOPE_00047	3.03e-208	-	5.4.2.12	-	G	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	phosphoglycerate mutase
HOFPAOPE_00048	1.63e-194	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HOFPAOPE_00049	1.14e-51	-	-	-	S	-	-	-	Prokaryotic RING finger family 1
HOFPAOPE_00050	3.49e-129	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HOFPAOPE_00051	1.78e-65	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ family
HOFPAOPE_00052	2.19e-33	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HOFPAOPE_00053	1.4e-256	-	-	-	S	ko:K09157	-	ko00000	Uncharacterised ACR (DUF711)
HOFPAOPE_00055	1.44e-81	ntpC	-	-	C	ko:K02119	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	subunit (C
HOFPAOPE_00056	4.29e-204	ntpI	-	-	C	ko:K02123	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Belongs to the V-ATPase 116 kDa subunit family
HOFPAOPE_00057	1.35e-26	ntpK	-	-	C	ko:K02124	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	ATP synthase subunit C
HOFPAOPE_00058	1.88e-49	-	-	-	C	ko:K02122	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Archaeal vacuolar-type H -ATPase subunit F
HOFPAOPE_00060	0.0	ntpA	3.6.3.14, 3.6.3.15	-	C	ko:K02117	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
HOFPAOPE_00061	2.47e-277	atpB	-	-	C	ko:K02118	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
HOFPAOPE_00062	7.36e-88	atpD	-	-	C	ko:K02120	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Produces ATP from ADP in the presence of a proton gradient across the membrane
HOFPAOPE_00065	2.44e-63	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
HOFPAOPE_00066	2.17e-308	dxs1	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HOFPAOPE_00071	4.07e-109	-	-	-	S	-	-	-	CYTH
HOFPAOPE_00072	2.67e-228	ilvE	2.6.1.42, 4.1.3.38	-	E	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HOFPAOPE_00073	2.01e-37	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_00077	1.85e-135	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HOFPAOPE_00078	2.63e-132	-	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HOFPAOPE_00079	5.13e-136	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HOFPAOPE_00080	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HOFPAOPE_00081	6.98e-140	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HOFPAOPE_00082	8.06e-114	gcp1	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HOFPAOPE_00083	1.74e-31	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HOFPAOPE_00084	1.65e-102	-	-	-	F	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_00085	3.21e-41	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HOFPAOPE_00086	3.88e-08	spoIIIAH	-	-	S	ko:K06397	-	ko00000	Stage III sporulation protein
HOFPAOPE_00087	1.14e-14	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HOFPAOPE_00089	1.12e-52	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
HOFPAOPE_00090	2.43e-19	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
HOFPAOPE_00091	1.35e-23	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HOFPAOPE_00093	9.36e-82	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HOFPAOPE_00095	1.29e-296	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HOFPAOPE_00096	4.05e-99	-	-	-	S	-	-	-	metal-dependent phosphohydrolase, HD sub domain
HOFPAOPE_00098	5.53e-154	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HOFPAOPE_00099	5.24e-65	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HOFPAOPE_00100	5.1e-44	yabR	-	-	J	ko:K07570,ko:K07571	-	ko00000	S1 RNA binding domain
HOFPAOPE_00101	8.82e-10	-	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HOFPAOPE_00102	5.45e-19	yabP	-	-	S	-	-	-	Sporulation protein YabP
HOFPAOPE_00103	5.98e-34	hslR	-	-	J	-	-	-	S4 domain protein
HOFPAOPE_00104	6.65e-36	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HOFPAOPE_00105	3.35e-124	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	MazG family
HOFPAOPE_00106	1.61e-165	-	-	-	S	ko:K06409	-	ko00000,ko02000	Polysaccharide biosynthesis protein
HOFPAOPE_00108	2.84e-182	hemZ	-	-	C	-	-	-	Coproporphyrinogen dehydrogenase
HOFPAOPE_00109	9.36e-56	-	-	-	S	-	-	-	domain protein
HOFPAOPE_00110	1.97e-67	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HOFPAOPE_00111	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HOFPAOPE_00112	4.26e-233	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	exonuclease
HOFPAOPE_00113	1.84e-47	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
HOFPAOPE_00114	5.69e-18	-	-	-	-	-	-	-	-
HOFPAOPE_00115	5.74e-29	-	-	-	-	-	-	-	-
HOFPAOPE_00116	2.15e-170	recN	-	-	L	ko:K03631,ko:K13582	ko04112,map04112	ko00000,ko00001,ko03400	May be involved in recombinational repair of damaged DNA
HOFPAOPE_00117	1.22e-53	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HOFPAOPE_00118	9.79e-80	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HOFPAOPE_00119	2.37e-128	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	FtsJ-like methyltransferase
HOFPAOPE_00120	1.64e-263	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HOFPAOPE_00121	1.22e-113	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HOFPAOPE_00122	5.17e-05	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
HOFPAOPE_00123	1.31e-82	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HOFPAOPE_00124	2.03e-109	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HOFPAOPE_00125	3.49e-102	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HOFPAOPE_00126	2.77e-141	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HOFPAOPE_00129	2.55e-176	-	-	-	EG	ko:K06295	-	ko00000	spore germination protein
HOFPAOPE_00130	1.26e-61	-	-	-	K	-	-	-	membrane
HOFPAOPE_00132	3.39e-108	-	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HOFPAOPE_00133	2.56e-90	-	-	-	P	ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HOFPAOPE_00134	3.54e-92	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HOFPAOPE_00135	2.92e-104	secF	-	-	U	ko:K03074	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HOFPAOPE_00136	2.65e-190	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HOFPAOPE_00137	2.59e-199	-	-	-	EK	-	-	-	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HOFPAOPE_00139	3.23e-21	ywqD	-	-	D	-	-	-	Cellulose biosynthesis protein BcsQ
HOFPAOPE_00140	4.05e-12	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HOFPAOPE_00141	2.93e-199	gcdB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
HOFPAOPE_00143	1.52e-245	spoIVA	-	-	DZ	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HOFPAOPE_00144	1.67e-104	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_00146	2.98e-140	rluC	5.4.99.23, 5.4.99.24	-	J	ko:K06179,ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HOFPAOPE_00147	6.32e-113	yfiH	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HOFPAOPE_00149	2.13e-84	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HOFPAOPE_00150	1.45e-45	-	-	-	DJ	ko:K06218	-	ko00000,ko02048	addiction module toxin, RelE StbE family
HOFPAOPE_00151	1.64e-30	-	-	-	-	-	-	-	-
HOFPAOPE_00152	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC
HOFPAOPE_00154	1.72e-123	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HOFPAOPE_00155	6.71e-156	rsmF	2.1.1.176, 2.1.1.178	-	J	ko:K03500,ko:K11392	-	ko00000,ko01000,ko03009	N-terminal domain of 16S rRNA methyltransferase RsmF
HOFPAOPE_00157	1.11e-77	-	-	-	C	-	-	-	LUD domain
HOFPAOPE_00158	8.62e-84	-	3.5.1.28	-	MT	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HOFPAOPE_00159	7.26e-139	-	-	-	GM	ko:K09691	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HOFPAOPE_00160	1.27e-92	wzm	-	-	GM	ko:K01992,ko:K09690	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	macromolecule localization
HOFPAOPE_00161	1.08e-79	-	5.2.1.8	-	O	ko:K01802	-	ko00000,ko01000	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HOFPAOPE_00162	5.11e-65	-	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
HOFPAOPE_00163	1.95e-130	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Hydrolase Family 3
HOFPAOPE_00164	0.000776	-	-	-	N	-	-	-	PFAM Kelch
HOFPAOPE_00165	5.7e-40	-	-	-	K	-	-	-	CarD-like/TRCF domain
HOFPAOPE_00166	1.45e-99	-	-	-	S	-	-	-	PKD domain
HOFPAOPE_00167	2.15e-195	-	-	-	C	-	-	-	Metallo-beta-lactamase superfamily
HOFPAOPE_00168	3.29e-29	-	-	-	DJ	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
HOFPAOPE_00169	4.24e-19	-	-	-	-	-	-	-	-
HOFPAOPE_00170	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HOFPAOPE_00171	1.78e-47	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HOFPAOPE_00172	4.04e-09	-	-	-	K	-	-	-	Helix-turn-helix
HOFPAOPE_00174	6.09e-11	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HOFPAOPE_00175	4.21e-202	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HOFPAOPE_00176	5.07e-126	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOFPAOPE_00177	6.26e-120	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	sugar transport system permease
HOFPAOPE_00178	0.0	-	-	-	O	ko:K03697	-	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
HOFPAOPE_00179	2.04e-41	-	2.7.8.41	-	I	ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HOFPAOPE_00182	1.34e-125	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HOFPAOPE_00183	3.18e-101	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOFPAOPE_00184	1.89e-135	cbiO	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOFPAOPE_00185	3.81e-139	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOFPAOPE_00186	5.32e-171	rlmI	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HOFPAOPE_00187	7.01e-213	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HOFPAOPE_00188	2.52e-199	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HOFPAOPE_00189	1.37e-62	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HOFPAOPE_00190	4.88e-79	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HOFPAOPE_00194	1.26e-217	-	3.2.1.133, 3.2.1.135, 3.2.1.54, 3.5.4.33	GH13	G	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko03016	Alpha amylase, catalytic domain protein
HOFPAOPE_00195	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Alpha amylase, catalytic domain
HOFPAOPE_00196	5.84e-239	-	-	-	S	ko:K03308	-	ko00000	Sodium:neurotransmitter symporter family
HOFPAOPE_00197	8.37e-30	-	-	-	L	-	-	-	Domain of unknown function (DUF4368)
HOFPAOPE_00198	2.6e-18	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 7.50
HOFPAOPE_00200	7.27e-85	-	-	-	V	-	-	-	ABC transporter, ATP-binding protein
HOFPAOPE_00203	5.9e-21	-	-	-	S	-	-	-	ABC-2 family transporter protein
HOFPAOPE_00206	9.65e-41	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
HOFPAOPE_00207	2.03e-109	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_00208	4.74e-200	-	-	-	S	-	-	-	AAA ATPase domain
HOFPAOPE_00209	9e-172	-	-	-	S	ko:K03308	-	ko00000	Sodium:neurotransmitter symporter family
HOFPAOPE_00212	4.11e-80	-	-	-	C	-	-	-	Flavodoxin
HOFPAOPE_00213	2.12e-87	-	-	-	S	-	-	-	conserved protein, contains double-stranded beta-helix domain
HOFPAOPE_00214	1.54e-81	-	-	-	C	-	-	-	Flavodoxin
HOFPAOPE_00215	3.7e-75	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HOFPAOPE_00216	3.04e-130	dacF1	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HOFPAOPE_00217	7.5e-245	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HOFPAOPE_00218	1.84e-231	-	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HOFPAOPE_00219	9.26e-116	-	-	-	S	ko:K09769	-	ko00000	metallophosphoesterase
HOFPAOPE_00220	3.6e-43	yqfD	-	-	M	ko:K06438	-	ko00000	Putative stage IV sporulation protein YqfD
HOFPAOPE_00222	5.2e-24	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HOFPAOPE_00223	2.43e-266	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	asparagine synthase
HOFPAOPE_00224	6.38e-20	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_00225	3.91e-92	-	-	-	O	-	-	-	cell wall binding repeat
HOFPAOPE_00226	1.47e-20	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HOFPAOPE_00227	1.45e-53	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HOFPAOPE_00228	2.92e-231	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HOFPAOPE_00229	1.06e-44	-	-	-	L	ko:K02238	-	ko00000,ko00002,ko02044	domain protein
HOFPAOPE_00230	6.86e-311	-	-	-	C	-	-	-	UPF0313 protein
HOFPAOPE_00231	2.47e-224	spoIIIE	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HOFPAOPE_00232	5.95e-92	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HOFPAOPE_00233	1.68e-107	tepA	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score
HOFPAOPE_00234	3.6e-125	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_00235	2.1e-21	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HOFPAOPE_00236	2.95e-63	rnmV	3.1.26.8	-	L	ko:K05985	-	ko00000,ko01000	Ribonuclease M5
HOFPAOPE_00237	7.12e-28	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HOFPAOPE_00238	1.07e-52	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Psort location CytoplasmicMembrane, score
HOFPAOPE_00240	1.05e-83	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Psort location Cytoplasmic, score
HOFPAOPE_00241	8.87e-49	hinT	-	-	FG	ko:K02503	-	ko00000,ko04147	Psort location Cytoplasmic, score
HOFPAOPE_00242	9.19e-63	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HOFPAOPE_00243	8.13e-231	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HOFPAOPE_00244	2.12e-169	-	-	-	C	-	-	-	FeS-containing Cyanobacterial-specific oxidoreductase
HOFPAOPE_00245	2.48e-20	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HOFPAOPE_00246	4.94e-37	-	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
HOFPAOPE_00247	2.36e-114	-	-	-	S	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HOFPAOPE_00248	1.13e-101	-	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HOFPAOPE_00250	5.64e-16	-	-	-	KT	-	-	-	BlaR1 peptidase M56
HOFPAOPE_00252	1.53e-130	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC domain protein
HOFPAOPE_00253	3.27e-125	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	S1 RNA binding domain protein
HOFPAOPE_00254	6.52e-59	-	-	-	O	-	-	-	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
HOFPAOPE_00255	1.41e-124	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
HOFPAOPE_00256	6.74e-119	-	-	-	S	ko:K03924	-	ko00000,ko01000	associated with various cellular activities
HOFPAOPE_00257	1.32e-11	-	-	-	E	-	-	-	protein (some members contain a von Willebrand factor type A (vWA) domain
HOFPAOPE_00258	1.93e-26	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
HOFPAOPE_00261	1.74e-49	-	-	-	K	-	-	-	LytTr DNA-binding domain
HOFPAOPE_00263	4.88e-112	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HOFPAOPE_00264	6.15e-68	-	-	-	V	ko:K01992,ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HOFPAOPE_00265	9.86e-202	-	-	-	E	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_00266	9.78e-147	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 9.98
HOFPAOPE_00267	1.25e-86	-	-	-	C	-	-	-	Nitroreductase family
HOFPAOPE_00268	8.11e-66	-	-	-	C	-	-	-	Nitroreductase family
HOFPAOPE_00269	9.69e-16	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HOFPAOPE_00270	7.58e-21	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HOFPAOPE_00271	3.16e-27	-	-	-	-	-	-	-	-
HOFPAOPE_00272	0.0	-	-	-	L	ko:K07496	-	ko00000	Transposase, IS605 OrfB family
HOFPAOPE_00273	1.97e-10	-	-	-	S	-	-	-	Mor transcription activator family
HOFPAOPE_00275	1.41e-138	-	-	-	-	-	-	-	-
HOFPAOPE_00282	3.69e-111	-	-	-	L	ko:K06400	-	ko00000	Resolvase, N terminal domain
HOFPAOPE_00285	1.37e-84	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HOFPAOPE_00286	7.6e-105	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HOFPAOPE_00287	2.27e-52	-	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HOFPAOPE_00288	2.36e-183	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HOFPAOPE_00289	1.58e-289	-	-	-	S	ko:K07137	-	ko00000	'oxidoreductase
HOFPAOPE_00290	7.35e-107	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	glucosamine-1-phosphate N-acetyltransferase activity
HOFPAOPE_00292	5.59e-39	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Membrane-associated phospholipid phosphatase
HOFPAOPE_00293	1.34e-187	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HOFPAOPE_00294	4.55e-84	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HOFPAOPE_00296	3.1e-193	-	-	-	M	-	-	-	Domain of unknown function (DUF1727)
HOFPAOPE_00297	3.15e-66	-	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HOFPAOPE_00298	2.68e-286	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HOFPAOPE_00299	1.48e-42	comF	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	ComF family
HOFPAOPE_00300	9.98e-112	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	MreB/Mbl protein
HOFPAOPE_00302	2.03e-87	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HOFPAOPE_00303	9.79e-162	potA	3.6.3.31	-	P	ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HOFPAOPE_00304	3.77e-86	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component I
HOFPAOPE_00305	5.63e-86	potC	-	-	E	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOFPAOPE_00306	8.5e-109	potD	-	-	P	ko:K11069,ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Spermidine putrescine-binding periplasmic protein
HOFPAOPE_00307	8.07e-88	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HOFPAOPE_00308	3.06e-108	tagH	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score
HOFPAOPE_00309	7.48e-65	-	4.1.1.35, 4.2.1.46	-	GM	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	ko00000,ko00001,ko00002,ko01000	epimerase dehydratase
HOFPAOPE_00310	1.34e-64	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HOFPAOPE_00316	3.01e-38	-	-	-	K	-	-	-	sequence-specific DNA binding
HOFPAOPE_00317	7.99e-155	-	-	-	K	-	-	-	Putative DNA-binding domain
HOFPAOPE_00319	4.56e-115	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HOFPAOPE_00320	4.36e-232	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HOFPAOPE_00321	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HOFPAOPE_00322	0.0	-	-	-	K	-	-	-	PD-(D/E)XK nuclease superfamily
HOFPAOPE_00323	6.44e-19	-	-	-	-	-	-	-	-
HOFPAOPE_00324	1.06e-110	-	3.1.26.3	-	K	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Double-stranded RNA binding motif
HOFPAOPE_00325	2.72e-68	-	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	cell wall hydrolase
HOFPAOPE_00326	2.03e-28	-	-	-	-	-	-	-	-
HOFPAOPE_00328	1.15e-119	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HOFPAOPE_00329	6.15e-296	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HOFPAOPE_00330	2.11e-122	speA	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Orn Lys Arg decarboxylase major
HOFPAOPE_00331	3.53e-15	scfA	-	-	S	-	-	-	RSAM-modified six-cysteine peptide
HOFPAOPE_00332	6.18e-278	scfB	-	-	C	ko:K06871	-	ko00000	Radical SAM
HOFPAOPE_00333	5.37e-115	-	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Psort location Cytoplasmic, score 8.96
HOFPAOPE_00334	3.04e-223	feoB2	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HOFPAOPE_00335	7.31e-12	-	-	-	P	ko:K04758	-	ko00000,ko02000	Fe2 transport system protein A
HOFPAOPE_00336	1.82e-103	-	-	-	I	-	-	-	Leucine-rich repeat (LRR) protein
HOFPAOPE_00337	3.53e-76	-	-	-	I	-	-	-	Domain of unknown function (DUF4430)
HOFPAOPE_00338	1.91e-106	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM Cobalt transport protein
HOFPAOPE_00339	0.0	-	-	-	G	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HOFPAOPE_00340	9.87e-308	purF_1	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HOFPAOPE_00341	9.18e-162	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HOFPAOPE_00342	6.35e-63	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HOFPAOPE_00343	4.08e-227	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HOFPAOPE_00344	8.7e-38	-	-	-	-	-	-	-	-
HOFPAOPE_00345	6.44e-137	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HOFPAOPE_00346	4.05e-256	gdhA	1.4.1.3, 1.4.1.4	-	C	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
HOFPAOPE_00347	1.38e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HOFPAOPE_00348	3.97e-213	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HOFPAOPE_00349	1.72e-79	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HOFPAOPE_00350	3.14e-300	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HOFPAOPE_00351	3.83e-202	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HOFPAOPE_00352	1.65e-107	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HOFPAOPE_00353	3.05e-148	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HOFPAOPE_00354	2.03e-100	-	-	-	S	ko:K07099	-	ko00000	Ser Thr phosphatase family protein
HOFPAOPE_00355	6.12e-229	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HOFPAOPE_00356	2.62e-74	-	3.4.13.19	-	E	ko:K01273	-	ko00000,ko00537,ko01000,ko01002,ko04147	Renal dipeptidase family protein
HOFPAOPE_00357	1.31e-26	-	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
HOFPAOPE_00358	3.98e-93	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOFPAOPE_00359	6.65e-143	ylqF	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HOFPAOPE_00360	7.41e-51	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HOFPAOPE_00361	1.77e-57	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HOFPAOPE_00362	4.03e-59	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HOFPAOPE_00363	1.51e-140	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HOFPAOPE_00364	4.52e-55	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HOFPAOPE_00365	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HOFPAOPE_00366	3.32e-21	-	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HOFPAOPE_00367	1.49e-60	-	-	-	S	-	-	-	S4 domain protein
HOFPAOPE_00368	2.35e-62	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HOFPAOPE_00369	4.81e-92	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HOFPAOPE_00370	6.63e-90	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HOFPAOPE_00371	1.46e-112	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HOFPAOPE_00372	1.18e-218	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HOFPAOPE_00373	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HOFPAOPE_00374	3.54e-27	-	-	-	S	-	-	-	Belongs to the UPF0342 family
HOFPAOPE_00375	3.29e-231	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HOFPAOPE_00376	5.16e-24	yunB	-	-	S	-	-	-	sporulation protein YunB
HOFPAOPE_00377	4.91e-28	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_00378	8.22e-120	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HOFPAOPE_00379	2.5e-98	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Xaa-Pro aminopeptidase
HOFPAOPE_00380	2.91e-75	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HOFPAOPE_00381	5.27e-25	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HOFPAOPE_00382	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HOFPAOPE_00383	8.26e-44	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HOFPAOPE_00384	1.45e-68	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	HD superfamily hydrolase involved in NAD metabolism
HOFPAOPE_00385	2.87e-50	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HOFPAOPE_00386	7.19e-39	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein, YhbY family
HOFPAOPE_00387	9.98e-78	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HOFPAOPE_00388	2.48e-157	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HOFPAOPE_00389	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HOFPAOPE_00390	3.82e-95	-	2.3.1.48	-	BK	ko:K07739	-	ko00000,ko01000,ko03016,ko03036	radical SAM domain protein
HOFPAOPE_00391	8.05e-108	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HOFPAOPE_00392	3.63e-144	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HOFPAOPE_00393	1.5e-210	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HOFPAOPE_00394	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HOFPAOPE_00395	1.08e-69	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HOFPAOPE_00396	9.71e-85	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOFPAOPE_00397	3.15e-66	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HOFPAOPE_00398	5.89e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
HOFPAOPE_00399	6.37e-97	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HOFPAOPE_00401	2.26e-141	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HOFPAOPE_00402	1.26e-144	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HOFPAOPE_00404	9.46e-17	-	-	-	S	-	-	-	sporulation protein, YlmC YmxH family
HOFPAOPE_00405	6.85e-98	-	-	-	S	-	-	-	DegV family
HOFPAOPE_00406	1.89e-39	-	-	-	S	-	-	-	Sporulation factor SpoIIGA
HOFPAOPE_00407	1.29e-109	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOFPAOPE_00410	4.91e-59	-	-	-	M	ko:K03442	-	ko00000,ko02000	Mechanosensitive ion channel
HOFPAOPE_00412	8.43e-165	pfkA	2.7.1.11	-	H	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HOFPAOPE_00413	1.62e-145	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
HOFPAOPE_00414	4.01e-17	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HOFPAOPE_00415	1.16e-101	-	-	-	S	-	-	-	Acyltransferase family
HOFPAOPE_00416	1.41e-251	pgcA	5.4.2.2, 5.4.2.8	-	G	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HOFPAOPE_00417	9.78e-82	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase GNAT family
HOFPAOPE_00418	5.17e-78	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HOFPAOPE_00419	9.18e-157	-	4.1.1.35, 4.2.1.46	-	GM	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	ko00000,ko00001,ko00002,ko01000	epimerase dehydratase
HOFPAOPE_00420	9.88e-158	-	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
HOFPAOPE_00421	2.15e-145	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HOFPAOPE_00422	2.05e-05	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HOFPAOPE_00423	6.49e-287	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HOFPAOPE_00424	5.52e-249	addB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
HOFPAOPE_00425	3.24e-61	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HOFPAOPE_00426	1.4e-73	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HOFPAOPE_00427	8.95e-210	aspC	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
HOFPAOPE_00428	4.88e-56	Lrp	-	-	K	-	-	-	Transcriptional regulator, AsnC family
HOFPAOPE_00430	4.73e-284	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HOFPAOPE_00431	1.23e-50	-	-	-	M	-	-	-	O-Antigen ligase
HOFPAOPE_00432	3.48e-87	-	-	-	M	-	-	-	Bacterial sugar transferase
HOFPAOPE_00433	7.86e-30	-	-	-	S	-	-	-	Belongs to the UPF0473 family
HOFPAOPE_00434	1.07e-130	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HOFPAOPE_00435	6.87e-45	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_00436	4.05e-56	-	-	-	T	-	-	-	EDD domain protein, DegV family
HOFPAOPE_00437	1.83e-55	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HOFPAOPE_00438	1.52e-23	-	-	-	U	-	-	-	Psort location Cytoplasmic, score 8.87
HOFPAOPE_00439	1.12e-25	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
HOFPAOPE_00440	8.33e-299	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HOFPAOPE_00441	5.68e-45	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HOFPAOPE_00442	3.5e-105	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HOFPAOPE_00444	4.47e-23	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HOFPAOPE_00445	4.21e-109	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HOFPAOPE_00446	7.65e-221	prkC	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HOFPAOPE_00447	3.06e-75	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
HOFPAOPE_00448	3.37e-155	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HOFPAOPE_00449	4.86e-138	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HOFPAOPE_00450	4.06e-79	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HOFPAOPE_00451	2.99e-112	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HOFPAOPE_00452	1.2e-63	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HOFPAOPE_00453	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HOFPAOPE_00455	2.78e-61	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HOFPAOPE_00456	3.2e-27	NPD7_560	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HOFPAOPE_00457	1.38e-119	yicC	-	-	S	ko:K03316	-	ko00000	Domain of unknown function (DUF1732)
HOFPAOPE_00458	4.28e-129	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HOFPAOPE_00460	3.37e-275	ispH	1.17.7.4, 2.7.4.25	-	J	ko:K00945,ko:K02945,ko:K03527	ko00240,ko00900,ko01100,ko01110,ko01130,ko03010,map00240,map00900,map01100,map01110,map01130,map03010	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	Ribosomal protein S1
HOFPAOPE_00461	3.64e-44	plsC_1	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HOFPAOPE_00462	1.31e-81	cmk	2.5.1.19, 2.7.4.25, 6.3.2.1	-	F	ko:K00800,ko:K00945,ko:K03977,ko:K13799	ko00240,ko00400,ko00410,ko00770,ko01100,ko01110,ko01130,ko01230,map00240,map00400,map00410,map00770,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	Belongs to the cytidylate kinase family. Type 1 subfamily
HOFPAOPE_00463	6.26e-173	-	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
HOFPAOPE_00464	3.16e-127	-	-	-	K	-	-	-	transcriptional regulator RpiR family
HOFPAOPE_00465	1.17e-96	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HOFPAOPE_00466	3.22e-129	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HOFPAOPE_00467	2.58e-108	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HOFPAOPE_00469	1.57e-192	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Starch-binding module 26
HOFPAOPE_00470	2.4e-57	-	-	-	M	-	-	-	GtrA-like protein
HOFPAOPE_00471	2.06e-87	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_00472	3e-39	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HOFPAOPE_00473	2.54e-233	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HOFPAOPE_00474	1.98e-54	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HOFPAOPE_00475	2.34e-28	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HOFPAOPE_00476	3.45e-43	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HOFPAOPE_00477	1.81e-144	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HOFPAOPE_00478	2.29e-170	ymfH	-	-	S	-	-	-	Belongs to the peptidase M16 family
HOFPAOPE_00479	4.37e-122	-	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HOFPAOPE_00480	1.45e-281	-	-	-	U	-	-	-	COG COG3210 Large exoproteins involved in heme utilization or adhesion
HOFPAOPE_00481	3.78e-74	-	-	-	Q	-	-	-	calcium- and calmodulin-responsive adenylate cyclase activity
HOFPAOPE_00482	2.1e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOFPAOPE_00483	1.73e-171	-	2.7.13.3	-	T	ko:K07645	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HOFPAOPE_00484	2.84e-126	cutR	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HOFPAOPE_00485	6.34e-166	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_00486	2.3e-125	-	-	-	CO	-	-	-	Redoxin
HOFPAOPE_00487	1.98e-27	-	-	-	K	-	-	-	negative regulation of transcription, DNA-templated
HOFPAOPE_00490	1.63e-11	idi	5.3.3.2	-	I	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	TIGRFAM isopentenyl-diphosphate delta-isomerase, type 1
HOFPAOPE_00491	4.13e-34	ytmA	-	-	E	-	-	-	Dienelactone hydrolase family
HOFPAOPE_00494	3.36e-26	-	-	-	-	-	-	-	-
HOFPAOPE_00501	3.56e-68	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HOFPAOPE_00502	3.09e-199	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HOFPAOPE_00503	5.35e-93	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	Uncharacterized protein family (UPF0051)
HOFPAOPE_00504	5.83e-296	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS assembly protein SufB
HOFPAOPE_00505	1.72e-126	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HOFPAOPE_00506	2.6e-51	-	-	-	K	-	-	-	Transcriptional regulator
HOFPAOPE_00507	6.43e-52	-	-	-	K	-	-	-	COG NOG13733 non supervised orthologous group
HOFPAOPE_00508	4.77e-15	-	-	-	S	-	-	-	SigmaK-factor processing regulatory protein BofA
HOFPAOPE_00509	7.81e-22	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HOFPAOPE_00510	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	PFAM DNA gyrase topoisomerase IV, subunit A
HOFPAOPE_00511	0.0	-	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase
HOFPAOPE_00512	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HOFPAOPE_00513	3.49e-61	radC	-	-	L	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HOFPAOPE_00514	1.02e-143	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HOFPAOPE_00516	1.56e-177	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HOFPAOPE_00517	1.03e-31	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_00518	1.44e-142	-	-	-	L	-	-	-	Radical SAM domain protein
HOFPAOPE_00521	2.1e-07	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HOFPAOPE_00523	2.98e-88	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HOFPAOPE_00524	2.51e-10	-	-	-	N	-	-	-	Domain of unknown function (DUF5057)
HOFPAOPE_00525	5.02e-05	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HOFPAOPE_00526	1.1e-60	-	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	DnaJ domain protein
HOFPAOPE_00527	1.17e-76	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_00528	7.01e-57	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
HOFPAOPE_00530	7.26e-80	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	IA, variant 1
HOFPAOPE_00532	1.81e-75	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HOFPAOPE_00533	3.46e-186	-	-	-	M	-	-	-	MBOAT, membrane-bound O-acyltransferase family
HOFPAOPE_00534	1.31e-30	-	-	-	IQ	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_00535	1.09e-138	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HOFPAOPE_00536	1.33e-203	-	6.1.1.13	-	Q	ko:K03367,ko:K04784	ko00473,ko01053,ko01503,ko02020,ko05150,map00473,map01053,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008,ko01504	AMP-binding enzyme
HOFPAOPE_00537	6.05e-53	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HOFPAOPE_00538	8.1e-78	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HOFPAOPE_00539	1.58e-74	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_00540	7.49e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF3006)
HOFPAOPE_00541	7.12e-83	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	PFAM Metallo-beta-lactamase superfamily
HOFPAOPE_00542	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HOFPAOPE_00543	2.42e-266	-	-	-	V	ko:K06147	-	ko00000,ko02000	Abc transporter
HOFPAOPE_00544	5.95e-37	-	-	-	K	-	-	-	MarR family
HOFPAOPE_00546	5.41e-56	yihY	-	-	H	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HOFPAOPE_00547	4.13e-90	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HOFPAOPE_00548	3.34e-58	-	-	-	Q	-	-	-	O-methyltransferase
HOFPAOPE_00550	2.87e-185	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOFPAOPE_00551	1.28e-224	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HOFPAOPE_00552	2.12e-98	-	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain
HOFPAOPE_00555	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HOFPAOPE_00556	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	aconitate hydratase
HOFPAOPE_00557	9.29e-246	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
HOFPAOPE_00558	6.02e-87	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HOFPAOPE_00559	8.51e-183	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HOFPAOPE_00560	3.21e-195	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HOFPAOPE_00561	1.36e-181	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HOFPAOPE_00562	1.58e-22	lyc2	3.2.1.17	-	M	ko:K01185,ko:K07273	-	ko00000,ko01000	family 25
HOFPAOPE_00563	1.38e-21	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HOFPAOPE_00564	2.69e-204	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HOFPAOPE_00565	3.16e-211	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HOFPAOPE_00566	2.64e-79	yigZ	2.1.1.45, 3.4.13.9	-	S	ko:K00560,ko:K01271	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000,ko01002	Uncharacterized protein family UPF0029
HOFPAOPE_00567	6.21e-39	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HOFPAOPE_00568	0.000442	-	3.4.13.22, 3.4.17.14	-	M	ko:K07260,ko:K18866	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	PFAM peptidase M15B and M15C, D,D-carboxypeptidase VanY endolysin
HOFPAOPE_00569	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HOFPAOPE_00574	5.5e-186	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_00575	2.58e-18	-	-	-	MV	-	-	-	N-acetylmuramoyl-L-alanine amidase
HOFPAOPE_00577	8.21e-13	-	-	-	-	-	-	-	-
HOFPAOPE_00579	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HOFPAOPE_00580	1.03e-272	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HOFPAOPE_00581	2.65e-72	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HOFPAOPE_00582	7.63e-73	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HOFPAOPE_00583	5.35e-211	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HOFPAOPE_00584	1.8e-64	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HOFPAOPE_00585	3.69e-183	yybT	-	-	T	-	-	-	domain protein
HOFPAOPE_00586	1.08e-300	rnj	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HOFPAOPE_00587	4.43e-78	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOFPAOPE_00588	4.86e-206	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine
HOFPAOPE_00589	1.79e-87	nifU	-	-	C	ko:K04488	-	ko00000	NifU-like N terminal domain
HOFPAOPE_00590	1.03e-29	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	capsular polysaccharide biosynthesis protein
HOFPAOPE_00591	7.35e-199	leuB	1.1.1.85	-	C	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HOFPAOPE_00592	8.84e-84	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HOFPAOPE_00593	8.21e-55	-	-	-	K	-	-	-	Helix-turn-helix
HOFPAOPE_00594	1.98e-57	ndoA	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HOFPAOPE_00596	2.14e-70	-	-	-	-	-	-	-	-
HOFPAOPE_00597	1.53e-98	-	-	-	T	-	-	-	HDOD domain
HOFPAOPE_00598	2.27e-71	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HOFPAOPE_00600	1.58e-192	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HOFPAOPE_00601	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	B3/4 domain
HOFPAOPE_00602	5.55e-37	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HOFPAOPE_00603	8.58e-36	-	-	-	-	-	-	-	-
HOFPAOPE_00604	0.0	actP	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
HOFPAOPE_00605	1.21e-47	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
HOFPAOPE_00606	2.15e-18	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HOFPAOPE_00607	5.08e-33	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	addiction module toxin, RelE StbE family
HOFPAOPE_00608	1.08e-144	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
HOFPAOPE_00609	8.79e-42	-	-	-	-	-	-	-	-
HOFPAOPE_00610	7.69e-166	-	2.1.1.72	-	L	ko:K07318	-	ko00000,ko01000,ko02048	D12 class N6 adenine-specific DNA methyltransferase
HOFPAOPE_00611	3.48e-69	-	-	-	-	-	-	-	-
HOFPAOPE_00614	9.96e-78	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	reverse transcriptase
HOFPAOPE_00615	1.19e-49	-	-	-	L	-	-	-	PFAM Integrase
HOFPAOPE_00618	7.08e-200	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HOFPAOPE_00619	6.36e-131	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	5,10-methylenetetrahydrofolate reductase
HOFPAOPE_00620	8.35e-65	metH2	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Vitamin B12 dependent methionine synthase, activation domain
HOFPAOPE_00621	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HOFPAOPE_00622	1.45e-13	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HOFPAOPE_00623	0.0	nifJ	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HOFPAOPE_00624	1.2e-71	-	3.4.16.4	-	V	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	L,D-transpeptidase catalytic domain
HOFPAOPE_00625	2.43e-77	KatE	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_00626	5.92e-66	-	-	-	S	-	-	-	HD domain
HOFPAOPE_00627	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HOFPAOPE_00628	5.07e-138	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HOFPAOPE_00631	5.28e-192	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
HOFPAOPE_00632	2.29e-177	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HOFPAOPE_00633	1.03e-91	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HOFPAOPE_00634	1.05e-76	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HOFPAOPE_00635	4.72e-107	pglK	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HOFPAOPE_00636	2.11e-71	-	-	-	S	ko:K13665	-	ko00000	Polysaccharide pyruvyl transferase
HOFPAOPE_00638	6.05e-59	-	-	-	H	-	-	-	Glycosyltransferase like family 2
HOFPAOPE_00639	1.67e-99	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HOFPAOPE_00640	1.82e-51	-	-	-	M	-	-	-	Glycosyl transferase family 8
HOFPAOPE_00641	6.14e-99	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose 3,5-epimerase
HOFPAOPE_00642	9.13e-114	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family
HOFPAOPE_00643	2.86e-195	rfbG	4.2.1.45	-	M	ko:K01709	ko00520,map00520	ko00000,ko00001,ko01000	CDP-glucose 4,6-dehydratase
HOFPAOPE_00644	5.54e-134	rfbF	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
HOFPAOPE_00645	1.73e-13	-	-	-	M	-	-	-	Bacterial sugar transferase
HOFPAOPE_00646	5.14e-43	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	NUBPL iron-transfer P-loop NTPase
HOFPAOPE_00647	7.59e-26	-	-	-	M	-	-	-	Chain length determinant protein
HOFPAOPE_00649	1.13e-67	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HOFPAOPE_00651	1.16e-99	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, TatD family
HOFPAOPE_00652	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOFPAOPE_00653	1.75e-221	-	-	-	S	ko:K03308	-	ko00000	Sodium:neurotransmitter symporter family
HOFPAOPE_00654	0.0	ppk	2.7.4.1	-	H	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HOFPAOPE_00655	6.03e-186	pfkA	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HOFPAOPE_00657	1.28e-42	-	-	-	S	-	-	-	YjbR
HOFPAOPE_00659	2.73e-135	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HOFPAOPE_00660	5.39e-250	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HOFPAOPE_00662	1.76e-45	smf	-	-	LU	ko:K04096	-	ko00000	DNA mediated transformation
HOFPAOPE_00663	5.36e-37	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HOFPAOPE_00664	1.23e-137	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HOFPAOPE_00665	3.78e-58	vanW	-	-	V	ko:K18346	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	VanW like protein
HOFPAOPE_00666	6.49e-104	-	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Monogalactosyldiacylglycerol synthase
HOFPAOPE_00667	1.9e-20	-	-	-	O	ko:K13963	ko05146,map05146	ko00000,ko00001	Belongs to the serpin family
HOFPAOPE_00668	5.38e-279	gltX	6.1.1.17, 6.1.1.24	-	J	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HOFPAOPE_00669	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), anti-codon binding domain
HOFPAOPE_00670	2.44e-92	fabG5	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HOFPAOPE_00671	1.82e-206	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HOFPAOPE_00672	5.13e-70	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HOFPAOPE_00673	2.77e-174	-	-	-	G	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOFPAOPE_00674	2.81e-119	-	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HOFPAOPE_00675	2.79e-122	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase catalytic
HOFPAOPE_00676	6.64e-119	-	-	-	L	-	-	-	Transposase, IS605 OrfB family
HOFPAOPE_00677	5.61e-87	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HOFPAOPE_00678	6.57e-96	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HOFPAOPE_00679	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HOFPAOPE_00680	2.07e-264	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HOFPAOPE_00681	7.05e-52	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HOFPAOPE_00682	1.33e-135	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins
HOFPAOPE_00683	5.4e-175	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HOFPAOPE_00684	5.32e-70	srtB	3.4.22.70	-	S	ko:K08600	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HOFPAOPE_00686	2.55e-254	megL	2.5.1.48, 4.4.1.11	-	E	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys Met metabolism
HOFPAOPE_00688	1.58e-124	-	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase family M23
HOFPAOPE_00689	7.78e-172	algI	-	-	M	ko:K19294	-	ko00000	MBOAT, membrane-bound O-acyltransferase family
HOFPAOPE_00690	5.8e-72	-	-	-	S	-	-	-	DHHW protein
HOFPAOPE_00691	1.66e-50	btuR	2.5.1.17	-	H	ko:K19221	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP
HOFPAOPE_00692	1.27e-61	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HOFPAOPE_00693	2.11e-116	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HOFPAOPE_00694	3.25e-114	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HOFPAOPE_00695	1.8e-40	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HOFPAOPE_00696	6.52e-168	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HOFPAOPE_00697	9.8e-56	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HOFPAOPE_00698	2.1e-53	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HOFPAOPE_00699	7.8e-123	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HOFPAOPE_00700	1.13e-86	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HOFPAOPE_00701	3.34e-23	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HOFPAOPE_00702	4.98e-44	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HOFPAOPE_00703	4.07e-76	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HOFPAOPE_00704	4.2e-59	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HOFPAOPE_00705	1.09e-112	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HOFPAOPE_00706	1.14e-36	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HOFPAOPE_00707	2.09e-76	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HOFPAOPE_00708	1.26e-96	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HOFPAOPE_00709	1.46e-54	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HOFPAOPE_00710	1.6e-89	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HOFPAOPE_00711	1.43e-24	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein
HOFPAOPE_00712	8.83e-69	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HOFPAOPE_00713	1.71e-208	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HOFPAOPE_00714	7.47e-110	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HOFPAOPE_00715	1.61e-140	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HOFPAOPE_00716	4.03e-16	-	-	-	J	-	-	-	COG2163 Ribosomal protein L14E L6E L27E
HOFPAOPE_00717	1.32e-38	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HOFPAOPE_00718	5.8e-18	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HOFPAOPE_00719	3.22e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HOFPAOPE_00720	3.7e-73	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HOFPAOPE_00721	3.43e-101	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HOFPAOPE_00722	6.18e-185	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOFPAOPE_00723	1.26e-59	rplQ	-	-	J	ko:K02879,ko:K16193	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HOFPAOPE_00725	5.79e-34	-	-	-	NU	-	-	-	CotH kinase protein
HOFPAOPE_00726	2.63e-129	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
HOFPAOPE_00727	9.32e-51	aroK	2.7.1.71	-	E	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HOFPAOPE_00728	5.92e-73	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Belongs to the sigma-70 factor family
HOFPAOPE_00729	3.06e-57	spoIIAB	2.7.11.1	-	T	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HOFPAOPE_00730	5.66e-27	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HOFPAOPE_00731	2.12e-135	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HOFPAOPE_00732	2.74e-130	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HOFPAOPE_00733	3.88e-66	-	-	-	S	-	-	-	Methyltransferase small domain
HOFPAOPE_00734	5.05e-11	-	-	-	C	-	-	-	4Fe-4S binding domain
HOFPAOPE_00735	2.8e-148	yaaT	-	-	S	-	-	-	PSP1 C-terminal domain protein
HOFPAOPE_00736	3e-17	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	TIGRFAM DNA polymerase III, delta
HOFPAOPE_00737	9.36e-47	yfcE1	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HOFPAOPE_00739	3.38e-12	-	-	-	-	-	-	-	-
HOFPAOPE_00741	4.34e-201	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HOFPAOPE_00742	3.24e-118	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HOFPAOPE_00743	2.49e-159	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HOFPAOPE_00745	3.36e-261	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
HOFPAOPE_00746	8.53e-34	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HOFPAOPE_00747	6.86e-98	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HOFPAOPE_00748	1.72e-58	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HOFPAOPE_00749	3.3e-186	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	synthase
HOFPAOPE_00750	1.6e-120	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HOFPAOPE_00751	2.73e-125	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HOFPAOPE_00752	2.55e-147	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HOFPAOPE_00753	8.48e-157	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HOFPAOPE_00754	1.13e-127	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	chorismate mutase
HOFPAOPE_00755	6.25e-30	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HOFPAOPE_00757	3.02e-218	-	3.2.1.1, 5.4.99.16	GH13	G	ko:K01176,ko:K05343	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha-amylase domain
HOFPAOPE_00759	1.61e-19	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_00760	2.15e-48	smf	-	-	LU	ko:K04096	-	ko00000	DNA mediated transformation
HOFPAOPE_00762	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HOFPAOPE_00763	4.3e-233	-	1.1.1.103, 1.1.1.14	-	E	ko:K00008,ko:K00060	ko00040,ko00051,ko00260,ko01100,map00040,map00051,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Glucose dehydrogenase C-terminus
HOFPAOPE_00764	5.05e-142	-	5.1.3.1	-	G	ko:K01783,ko:K17195	ko00030,ko00040,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3 epimerase family
HOFPAOPE_00765	4.16e-267	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HOFPAOPE_00766	6.03e-216	-	-	-	E	-	-	-	Glucose dehydrogenase C-terminus
HOFPAOPE_00767	1.1e-191	-	-	-	G	-	-	-	Fructose-bisphosphate aldolase class-II
HOFPAOPE_00768	2.47e-159	-	-	-	G	-	-	-	Phosphomethylpyrimidine kinase
HOFPAOPE_00769	1.78e-218	-	-	-	C	ko:K18471	ko00640,map00640	ko00000,ko00001,ko01000	Aldo/keto reductase family
HOFPAOPE_00770	9.29e-76	-	-	-	K	-	-	-	Transcriptional regulator, DeoR family
HOFPAOPE_00771	1.23e-238	-	-	-	C	-	-	-	Sodium:dicarboxylate symporter family
HOFPAOPE_00772	5.64e-216	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HOFPAOPE_00773	2.36e-265	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
HOFPAOPE_00775	7.7e-25	-	-	-	-	-	-	-	-
HOFPAOPE_00778	5.32e-91	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HOFPAOPE_00781	4.52e-244	csn1	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HOFPAOPE_00782	2.98e-44	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HOFPAOPE_00783	3.34e-32	-	-	-	-	-	-	-	-
HOFPAOPE_00785	7.65e-10	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HOFPAOPE_00788	1.05e-273	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HOFPAOPE_00789	2.55e-95	thyX	2.1.1.148	-	H	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	ko00000,ko00001,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
HOFPAOPE_00790	3.42e-85	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HOFPAOPE_00791	3.63e-60	-	-	-	S	ko:K01163	-	ko00000	conserved protein (DUF2156)
HOFPAOPE_00792	3.57e-06	-	-	-	S	ko:K01163	-	ko00000	Psort location Cytoplasmic, score 8.96
HOFPAOPE_00793	1.54e-66	yajL	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
HOFPAOPE_00794	3.05e-63	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
HOFPAOPE_00795	1.18e-105	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HOFPAOPE_00796	6.17e-179	yhbU_1	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HOFPAOPE_00797	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HOFPAOPE_00800	3.36e-139	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HOFPAOPE_00801	1.01e-26	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HOFPAOPE_00802	3.23e-90	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HOFPAOPE_00803	9.04e-78	-	-	-	EG	-	-	-	EamA-like transporter family
HOFPAOPE_00804	1.17e-72	-	-	-	S	-	-	-	IA, variant 3
HOFPAOPE_00805	1.47e-206	-	-	-	E	ko:K03310	-	ko00000	amino acid carrier protein
HOFPAOPE_00806	2.48e-101	-	-	-	S	ko:K07023	-	ko00000	HD domain
HOFPAOPE_00807	0.0	ilvD	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Dehydratase family
HOFPAOPE_00808	0.0	fusA2	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	translation elongation
HOFPAOPE_00809	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
HOFPAOPE_00810	2.91e-133	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HOFPAOPE_00811	7.87e-146	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HOFPAOPE_00812	1.38e-238	-	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC-type multidrug transport system ATPase and permease
HOFPAOPE_00813	1.92e-242	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HOFPAOPE_00814	6.68e-290	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HOFPAOPE_00815	7.28e-133	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HOFPAOPE_00816	2.53e-244	pgk	2.7.2.3, 5.3.1.1	-	G	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HOFPAOPE_00817	2.57e-93	trmL	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HOFPAOPE_00822	6.9e-23	-	-	-	-	-	-	-	-
HOFPAOPE_00823	2.35e-37	-	-	-	M	-	-	-	heme binding
HOFPAOPE_00824	1.47e-67	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HOFPAOPE_00825	6.4e-79	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HOFPAOPE_00827	7.06e-34	-	-	-	S	-	-	-	PFAM ErfK YbiS YcfS YnhG family protein
HOFPAOPE_00828	2.09e-08	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HOFPAOPE_00830	6.63e-94	pdaB	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HOFPAOPE_00831	1.57e-254	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HOFPAOPE_00832	1.59e-96	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine O-acetyltransferase
HOFPAOPE_00833	5.17e-56	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
HOFPAOPE_00834	5.2e-199	rimO	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
HOFPAOPE_00835	1.96e-68	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HOFPAOPE_00836	1.15e-196	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HOFPAOPE_00837	9.75e-71	prmB	2.1.1.297, 2.1.1.298	-	J	ko:K02493,ko:K07320	-	ko00000,ko01000,ko03009,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HOFPAOPE_00838	2.87e-125	prmC	-	-	S	-	-	-	Protein of unknown function (DUF1385)
HOFPAOPE_00839	3.06e-153	yclK	2.7.13.3	-	T	ko:K07636,ko:K07769	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HOFPAOPE_00840	4.45e-139	-	-	-	K	-	-	-	response regulator receiver
HOFPAOPE_00841	7.2e-37	-	-	-	S	-	-	-	Tetratricopeptide repeat
HOFPAOPE_00842	1.02e-84	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HOFPAOPE_00843	4.53e-73	-	-	-	S	-	-	-	dinuclear metal center protein, YbgI
HOFPAOPE_00844	1.52e-44	trmK	2.1.1.217	-	J	ko:K06967	-	ko00000,ko01000,ko03016	tRNA (adenine(22)-N(1))-methyltransferase
HOFPAOPE_00845	9.37e-27	-	-	-	C	-	-	-	Domain of unknown function (DUF1858)
HOFPAOPE_00846	1.03e-214	comM	-	-	O	ko:K06400,ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
HOFPAOPE_00847	1.26e-24	sigH	-	-	K	ko:K03091	-	ko00000,ko03021	Belongs to the sigma-70 factor family
HOFPAOPE_00848	3e-48	-	-	-	K	-	-	-	Probable zinc-ribbon domain
HOFPAOPE_00855	2.89e-59	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HOFPAOPE_00856	5.98e-33	-	-	-	S	ko:K19411	-	ko00000	PFAM UvrB uvrC
HOFPAOPE_00857	1.09e-120	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in proteins
HOFPAOPE_00858	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HOFPAOPE_00860	1.33e-258	-	-	-	S	-	-	-	Domain of unknown function (DUF4143)
HOFPAOPE_00861	2.63e-31	ylqC	-	-	L	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HOFPAOPE_00862	5.61e-39	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HOFPAOPE_00863	2.43e-221	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HOFPAOPE_00864	9.77e-29	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HOFPAOPE_00865	2.23e-182	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
HOFPAOPE_00866	1.67e-82	ybeY	3.5.4.5	-	S	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HOFPAOPE_00867	6.33e-12	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_00868	7e-148	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HOFPAOPE_00870	9.29e-81	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HOFPAOPE_00871	6.36e-299	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HOFPAOPE_00872	1.11e-59	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HOFPAOPE_00873	1.16e-124	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HOFPAOPE_00874	8.8e-48	ptsH	-	-	G	ko:K11184,ko:K11189	-	ko00000,ko02000	phosphocarrier, HPr family
HOFPAOPE_00875	3.02e-274	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HOFPAOPE_00876	8.18e-70	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HOFPAOPE_00877	3.61e-69	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HOFPAOPE_00878	3.1e-32	-	-	-	C	-	-	-	ATP synthesis coupled proton transport
HOFPAOPE_00880	6.15e-31	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HOFPAOPE_00881	2.14e-136	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HOFPAOPE_00883	7.97e-233	spoVD	3.4.16.4	-	M	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	stage V sporulation protein D
HOFPAOPE_00884	1.57e-123	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HOFPAOPE_00885	2.49e-124	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HOFPAOPE_00886	2.22e-176	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HOFPAOPE_00887	1.98e-182	murA2	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HOFPAOPE_00889	1.6e-155	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HOFPAOPE_00890	7.8e-101	bcsP	-	-	S	ko:K07080	-	ko00000	TRAP transporter solute receptor, TAXI family
HOFPAOPE_00891	8.16e-213	gltS	-	-	P	ko:K03312	-	ko00000,ko02000	Catalyzes the sodium-dependent transport of glutamate
HOFPAOPE_00893	1.02e-168	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Choloylglycine hydrolase
HOFPAOPE_00894	6.14e-116	eriC	-	-	P	ko:K03281	-	ko00000	Chloride channel
HOFPAOPE_00897	7.99e-19	-	-	-	S	-	-	-	COG NOG17973 non supervised orthologous group
HOFPAOPE_00898	3.83e-211	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HOFPAOPE_00899	6.24e-134	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HOFPAOPE_00900	2.5e-59	trpH	3.1.3.97	-	S	ko:K07053	-	ko00000,ko01000	PHP domain
HOFPAOPE_00901	3.66e-84	femX	2.3.2.10, 2.3.2.16	-	V	ko:K05363,ko:K11693	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Methicillin resistance
HOFPAOPE_00903	2.22e-80	-	-	-	T	-	-	-	Histidine kinase
HOFPAOPE_00904	1.41e-90	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HOFPAOPE_00906	2.28e-29	-	-	-	QT	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_00907	1.16e-21	-	-	-	S	-	-	-	Fic/DOC family
HOFPAOPE_00908	4.88e-46	-	-	-	M	ko:K07273	-	ko00000	lysozyme activity
HOFPAOPE_00909	6.42e-42	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	ParE toxin of type II toxin-antitoxin system, parDE
HOFPAOPE_00910	2.43e-28	-	-	-	-	-	-	-	-
HOFPAOPE_00911	3.19e-34	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HOFPAOPE_00912	2.78e-14	-	-	-	-	-	-	-	-
HOFPAOPE_00913	8.18e-91	-	-	-	S	-	-	-	Protein of unknown function DUF262
HOFPAOPE_00914	3.85e-171	haeIIIM	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HOFPAOPE_00915	1.33e-82	-	-	-	-	-	-	-	-
HOFPAOPE_00916	5.17e-51	-	-	-	S	-	-	-	non supervised orthologous group
HOFPAOPE_00919	8.25e-79	-	-	-	S	ko:K07025	-	ko00000	HAD-hyrolase-like
HOFPAOPE_00920	5.04e-100	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HOFPAOPE_00921	8.06e-43	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_00922	8.23e-28	-	-	-	S	-	-	-	Domain of unknown function (DUF3783)
HOFPAOPE_00923	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HOFPAOPE_00924	2.24e-52	-	-	-	S	-	-	-	TIGRFAM C_GCAxxG_C_C family
HOFPAOPE_00925	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HOFPAOPE_00926	1.02e-264	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
HOFPAOPE_00927	1.55e-104	-	3.4.19.11	-	EM	ko:K01308	-	ko00000,ko01000,ko01002	Carboxypeptidase
HOFPAOPE_00928	1.72e-85	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HOFPAOPE_00929	1.36e-87	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HOFPAOPE_00930	2.73e-84	-	-	-	H	-	-	-	Psort location Cytoplasmic, score 7.50
HOFPAOPE_00931	1.08e-117	-	-	-	V	ko:K03327	-	ko00000,ko02000	Mate efflux family protein
HOFPAOPE_00932	9.75e-67	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HOFPAOPE_00933	1.6e-17	-	-	-	S	-	-	-	Psort location
HOFPAOPE_00935	6.17e-41	-	-	-	-	-	-	-	-
HOFPAOPE_00937	9.73e-30	-	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Peptidase S24-like
HOFPAOPE_00938	2.39e-180	-	-	-	V	-	-	-	ATPase associated with various cellular activities
HOFPAOPE_00939	1.2e-13	-	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	signal peptide processing
HOFPAOPE_00945	3.29e-78	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HOFPAOPE_00946	7.8e-275	-	-	-	G	-	-	-	Alpha amylase, catalytic domain
HOFPAOPE_00947	2.65e-215	-	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HOFPAOPE_00948	1.28e-05	-	-	-	-	-	-	-	-
HOFPAOPE_00949	1.72e-62	mleP3	-	-	S	ko:K07088	-	ko00000	auxin-activated signaling pathway
HOFPAOPE_00950	6.48e-117	-	-	-	K	-	-	-	WYL domain
HOFPAOPE_00951	3.11e-28	bglC	-	-	K	-	-	-	AraC-type DNA-binding domain-containing proteins
HOFPAOPE_00953	2.03e-19	-	-	-	S	-	-	-	HIRAN domain
HOFPAOPE_00954	7.13e-193	-	2.6.1.59	-	E	ko:K02805	-	ko00000,ko01000,ko01007	Belongs to the DegT DnrJ EryC1 family
HOFPAOPE_00955	1.1e-33	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	sporulation transcriptional regulator SpoIIID
HOFPAOPE_00956	7.7e-49	-	-	-	D	-	-	-	protein involved in cytokinesis, contains TGc (transglutaminase protease-like) domain
HOFPAOPE_00957	3.66e-65	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HOFPAOPE_00958	5.98e-56	-	-	-	S	-	-	-	COG COG0110 Acetyltransferase (isoleucine patch superfamily)
HOFPAOPE_00959	9.97e-11	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HOFPAOPE_00962	6.42e-87	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HOFPAOPE_00963	1.31e-45	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HOFPAOPE_00964	3.51e-64	-	-	-	G	-	-	-	YjeF-related protein N-terminus
HOFPAOPE_00965	1.17e-10	-	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 39
HOFPAOPE_00966	6.21e-49	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HOFPAOPE_00967	1.24e-247	capD	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
HOFPAOPE_00968	7.94e-298	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HOFPAOPE_00970	1.7e-191	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HOFPAOPE_00971	1.68e-157	-	4.1.3.39	-	E	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	br01602,ko00000,ko00001,ko00002,ko01000	HMGL-like
HOFPAOPE_00972	4.93e-158	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
HOFPAOPE_00973	1.96e-210	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HOFPAOPE_00974	7.53e-162	pdxB	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
HOFPAOPE_00975	2.23e-116	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_00976	2.79e-55	-	-	-	S	-	-	-	IA, variant 3
HOFPAOPE_00977	9.12e-119	-	-	-	S	-	-	-	protein conserved in bacteria
HOFPAOPE_00978	8.55e-175	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_00979	1.25e-69	-	-	-	S	-	-	-	integral membrane protein
HOFPAOPE_00980	1.18e-182	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HOFPAOPE_00981	1.75e-206	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HOFPAOPE_00982	2.32e-60	-	-	-	S	-	-	-	DHHW protein
HOFPAOPE_00983	3.6e-51	-	-	-	F	-	-	-	Belongs to the Nudix hydrolase family
HOFPAOPE_00985	5.61e-103	yacO	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOFPAOPE_00987	1.01e-83	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HOFPAOPE_00989	2.63e-109	-	-	-	GM	-	-	-	Methyltransferase FkbM domain
HOFPAOPE_00990	1.2e-149	-	-	-	S	ko:K06923	-	ko00000	ATPase (AAA superfamily)
HOFPAOPE_00991	1.2e-10	-	-	-	M	-	-	-	NlpC/P60 family
HOFPAOPE_00992	5.7e-100	alkA	4.2.99.18	-	L	ko:K03660	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	8-oxoguanine DNA glycosylase
HOFPAOPE_00993	1.35e-75	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_00996	3.83e-24	-	-	-	K	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HOFPAOPE_00997	1.48e-80	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HOFPAOPE_00998	1.1e-145	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HOFPAOPE_00999	3.62e-156	nfnA	1.18.1.2, 1.19.1.1	-	CH	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	ko00000,ko00001,ko01000	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HOFPAOPE_01000	1.28e-257	gltA	1.17.1.9, 1.4.1.13, 1.4.1.14	-	C	ko:K00123,ko:K00266	ko00250,ko00630,ko00680,ko00910,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00250,map00630,map00680,map00910,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko01000	glutamate synthase (NADPH), homotetrameric
HOFPAOPE_01001	2.69e-150	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	Potassium transporter peripheral membrane component
HOFPAOPE_01002	4.27e-189	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	potassium uptake protein TrkH
HOFPAOPE_01003	1.96e-82	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HOFPAOPE_01004	2.35e-108	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HOFPAOPE_01005	7.93e-53	-	-	-	M	-	-	-	Papain family cysteine protease
HOFPAOPE_01006	3.3e-209	yrvN	-	-	L	ko:K07478	-	ko00000	ATPase, AAA family
HOFPAOPE_01007	5.46e-12	aml1	-	-	G	-	-	-	alpha-amylase
HOFPAOPE_01008	1.21e-217	-	-	-	G	-	-	-	Alpha amylase, catalytic domain
HOFPAOPE_01009	4.21e-05	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HOFPAOPE_01010	2.77e-11	-	-	-	S	-	-	-	Helix-turn-helix domain
HOFPAOPE_01011	4.65e-38	-	-	-	S	-	-	-	Ferredoxin thioredoxin reductase catalytic beta chain
HOFPAOPE_01012	4.02e-42	-	-	-	O	-	-	-	Belongs to the thioredoxin family
HOFPAOPE_01013	5.13e-28	-	-	-	K	-	-	-	sequence-specific DNA binding
HOFPAOPE_01016	7.49e-48	-	-	-	T	-	-	-	Forkhead associated domain
HOFPAOPE_01017	1.04e-90	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
HOFPAOPE_01018	5.01e-190	-	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HOFPAOPE_01021	3.11e-145	-	-	-	NU	-	-	-	outer membrane autotransporter barrel domain protein
HOFPAOPE_01022	3.29e-107	-	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Psort location CytoplasmicMembrane, score 9.49
HOFPAOPE_01025	7.94e-44	-	-	-	S	-	-	-	Carboxypeptidase regulatory-like domain
HOFPAOPE_01027	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	Type VII secretion protein EssC
HOFPAOPE_01028	1.08e-40	-	-	-	KT	-	-	-	LytTr DNA-binding domain
HOFPAOPE_01030	4.81e-13	-	-	-	-	-	-	-	-
HOFPAOPE_01032	5.73e-24	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
HOFPAOPE_01037	2.13e-09	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HOFPAOPE_01039	8.09e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
HOFPAOPE_01043	2.84e-11	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
HOFPAOPE_01044	1.66e-17	-	-	-	S	-	-	-	Terminase small subunit
HOFPAOPE_01045	5.34e-202	-	-	-	S	-	-	-	phage terminase, large subunit, PBSX family
HOFPAOPE_01046	9.29e-117	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_01047	3.14e-82	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_01049	9.07e-152	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_01059	1.11e-66	-	-	-	S	-	-	-	Baseplate J-like protein
HOFPAOPE_01061	2.15e-130	-	-	-	O	-	-	-	Holliday junction DNA helicase ruvB N-terminus
HOFPAOPE_01062	8.64e-90	-	-	-	-	-	-	-	-
HOFPAOPE_01064	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
HOFPAOPE_01065	5.95e-91	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HOFPAOPE_01066	7.06e-171	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOFPAOPE_01067	3.37e-67	-	-	-	-	-	-	-	-
HOFPAOPE_01068	1.25e-85	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HOFPAOPE_01069	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HOFPAOPE_01072	3.71e-11	ynzC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF896)
HOFPAOPE_01073	7.26e-134	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
HOFPAOPE_01074	1.61e-34	-	-	-	K	-	-	-	Helix-turn-helix domain
HOFPAOPE_01075	5.59e-118	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_01076	1.32e-17	-	-	-	-	-	-	-	-
HOFPAOPE_01077	1.66e-91	-	-	-	S	-	-	-	Transporter, auxin efflux carrier (AEC) family protein
HOFPAOPE_01079	3.14e-28	-	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HOFPAOPE_01080	1.64e-185	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HOFPAOPE_01081	1.75e-83	ylbM	-	-	S	-	-	-	HIGH Nucleotidyl Transferase
HOFPAOPE_01083	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HOFPAOPE_01084	2.09e-119	-	-	-	M	-	-	-	Phosphotransferase enzyme family
HOFPAOPE_01085	7.95e-63	ydhO	3.4.14.13	-	M	ko:K20742,ko:K21471	-	ko00000,ko01000,ko01002,ko01011	Peptidoglycan-binding domain 1 protein
HOFPAOPE_01086	8.46e-52	-	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
HOFPAOPE_01087	2.35e-190	ttcA	-	-	D	-	-	-	Belongs to the TtcA family
HOFPAOPE_01088	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOFPAOPE_01089	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOFPAOPE_01090	2.5e-24	-	-	-	K	-	-	-	Helix-turn-helix
HOFPAOPE_01091	2.45e-51	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HOFPAOPE_01092	1.2e-184	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HOFPAOPE_01094	7.73e-21	-	-	-	K	-	-	-	PFAM helix-turn-helix domain protein
HOFPAOPE_01095	2.58e-205	-	-	-	S	-	-	-	Fic/DOC family
HOFPAOPE_01097	2.21e-210	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
HOFPAOPE_01098	1.85e-38	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HOFPAOPE_01099	1.01e-43	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HOFPAOPE_01100	1.67e-155	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HOFPAOPE_01101	1.87e-43	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_01102	1.07e-300	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HOFPAOPE_01103	4.4e-37	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_01104	5.97e-18	-	-	-	M	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HOFPAOPE_01105	3.68e-41	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_01106	4.4e-25	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_01107	6.51e-177	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HOFPAOPE_01108	7.1e-135	sua	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HOFPAOPE_01109	5.13e-52	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HOFPAOPE_01110	7.37e-38	-	-	GH23	M	ko:K08309	-	ko00000,ko01000,ko01011	transglycosylase
HOFPAOPE_01111	2.3e-229	apeA	-	-	E	-	-	-	M18 family aminopeptidase
HOFPAOPE_01113	6.91e-36	-	-	-	S	-	-	-	23S rRNA-intervening sequence protein
HOFPAOPE_01114	4.63e-35	-	-	-	M	-	-	-	CHAP domain
HOFPAOPE_01115	1.77e-82	-	-	-	T	-	-	-	GHKL domain
HOFPAOPE_01116	8.42e-43	-	-	-	KT	-	-	-	LytTr DNA-binding domain
HOFPAOPE_01118	4.46e-111	hprA	1.1.1.29, 1.1.1.399, 1.1.1.95	-	CH	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
HOFPAOPE_01119	8.74e-56	-	-	-	S	-	-	-	PFAM Haloacid dehalogenase domain protein hydrolase
HOFPAOPE_01120	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphoribosylformylglycinamidine synthase
HOFPAOPE_01121	1.51e-98	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HOFPAOPE_01122	6.02e-47	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HOFPAOPE_01123	9.26e-85	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HOFPAOPE_01124	2.11e-138	tktA	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, thiamine diphosphate binding domain
HOFPAOPE_01125	4.7e-158	tklB	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
HOFPAOPE_01127	5.77e-209	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HOFPAOPE_01128	2.17e-23	-	-	-	S	-	-	-	Thioesterase family
HOFPAOPE_01129	8.42e-42	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HOFPAOPE_01131	7.56e-73	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HOFPAOPE_01132	2.19e-204	msmX	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HOFPAOPE_01133	3.19e-216	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Psort location Cytoplasmic, score
HOFPAOPE_01134	2.89e-101	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HOFPAOPE_01135	1.78e-90	ftsX	-	-	D	ko:K09811,ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division
HOFPAOPE_01136	7.17e-51	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HOFPAOPE_01138	1.01e-52	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HOFPAOPE_01140	2.35e-39	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HOFPAOPE_01141	2.25e-50	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HOFPAOPE_01142	2.95e-42	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HOFPAOPE_01143	1.32e-71	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
HOFPAOPE_01144	5.05e-162	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HOFPAOPE_01145	2.78e-246	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine
HOFPAOPE_01146	1.8e-59	-	-	-	K	-	-	-	Transcriptional regulator
HOFPAOPE_01147	5.12e-174	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HOFPAOPE_01148	9.99e-99	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma-70 region 2
HOFPAOPE_01154	2.89e-253	-	-	-	S	ko:K03308	-	ko00000	Sodium:neurotransmitter symporter family
HOFPAOPE_01155	2.4e-32	-	-	-	S	-	-	-	Ion channel
HOFPAOPE_01156	1.3e-79	-	-	-	O	-	-	-	4Fe-4S single cluster domain
HOFPAOPE_01157	7.67e-34	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HOFPAOPE_01158	4.26e-94	-	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HOFPAOPE_01159	7.86e-37	-	-	-	S	-	-	-	addiction module toxin, Txe YoeB family
HOFPAOPE_01160	2.06e-34	-	2.3.1.15	-	D	ko:K08591,ko:K19159	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004,ko02048	toxin-antitoxin pair type II binding
HOFPAOPE_01163	1.13e-49	-	-	-	S	-	-	-	Cupin domain protein
HOFPAOPE_01164	6.5e-74	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
HOFPAOPE_01165	4.71e-219	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HOFPAOPE_01166	9.08e-67	-	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
HOFPAOPE_01167	3.27e-211	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HOFPAOPE_01168	1.57e-68	-	-	-	C	-	-	-	Flavodoxin domain
HOFPAOPE_01169	5.16e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF3793)
HOFPAOPE_01170	2.45e-100	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HOFPAOPE_01171	3.36e-35	-	-	-	P	-	-	-	Heavy-metal-associated domain
HOFPAOPE_01173	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HOFPAOPE_01174	1.63e-39	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
HOFPAOPE_01175	8.03e-32	-	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
HOFPAOPE_01176	1.24e-43	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_01177	7.54e-96	-	-	-	S	ko:K06889	-	ko00000	thiolester hydrolase activity
HOFPAOPE_01178	0.0	yhgF	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain
HOFPAOPE_01179	1.37e-161	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HOFPAOPE_01180	2.93e-72	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
HOFPAOPE_01181	3.11e-105	fnt	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
HOFPAOPE_01182	4.49e-74	yuaJ	-	-	S	ko:K16789	-	ko00000,ko02000	proton-coupled thiamine transporter YuaJ
HOFPAOPE_01183	1.59e-08	-	-	-	S	-	-	-	Spore coat associated protein JA (CotJA)
HOFPAOPE_01184	1.87e-12	cotJB	-	-	S	ko:K06333	-	ko00000	COG NOG18028 non supervised orthologous group
HOFPAOPE_01185	3.17e-09	cotJC	-	-	P	ko:K06334,ko:K07217	-	ko00000	catalase activity
HOFPAOPE_01186	5.28e-140	-	-	-	K	-	-	-	LysR substrate binding domain
HOFPAOPE_01187	5.78e-277	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HOFPAOPE_01188	1.72e-14	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HOFPAOPE_01189	7.82e-115	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HOFPAOPE_01190	1.16e-62	maf	-	-	D	ko:K06287	-	ko00000	Maf-like protein
HOFPAOPE_01191	8.73e-144	-	-	-	S	-	-	-	CobW P47K family protein
HOFPAOPE_01193	8.27e-112	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HOFPAOPE_01194	2.93e-85	tcyB	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HOFPAOPE_01195	2.1e-73	fliY1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HOFPAOPE_01196	4.56e-91	-	-	-	L	ko:K06400	-	ko00000	Resolvase, N terminal domain
HOFPAOPE_01197	1.41e-79	cotJC	-	-	P	ko:K06334	-	ko00000	PFAM Manganese containing catalase
HOFPAOPE_01198	3.06e-98	wecE	2.6.1.59	-	E	ko:K02805	-	ko00000,ko01000,ko01007	Belongs to the DegT DnrJ EryC1 family
HOFPAOPE_01199	8.81e-55	-	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
HOFPAOPE_01200	7.32e-111	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HOFPAOPE_01201	1.82e-87	-	-	-	C	-	-	-	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
HOFPAOPE_01202	8.24e-44	epsJ	-	GT2	S	ko:K19425,ko:K19427	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
HOFPAOPE_01204	6.68e-17	-	-	-	C	-	-	-	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
HOFPAOPE_01205	3.19e-58	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
HOFPAOPE_01206	7.56e-37	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HOFPAOPE_01207	3.15e-116	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HOFPAOPE_01208	6.75e-92	-	-	-	C	-	-	-	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term
HOFPAOPE_01209	4.27e-123	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HOFPAOPE_01210	5.58e-74	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
HOFPAOPE_01211	1.43e-114	-	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
HOFPAOPE_01212	4.98e-135	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HOFPAOPE_01214	2.75e-142	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HOFPAOPE_01215	4.23e-121	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HOFPAOPE_01216	6.04e-141	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HOFPAOPE_01217	8.14e-71	pglC	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HOFPAOPE_01221	7.19e-73	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HOFPAOPE_01222	9.34e-27	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOFPAOPE_01223	0.0	czcA	-	-	V	ko:K03296	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HOFPAOPE_01224	1.23e-73	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HOFPAOPE_01226	2.34e-153	ntpI	-	-	C	ko:K02123	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Belongs to the V-ATPase 116 kDa subunit family
HOFPAOPE_01227	5.39e-38	ntpK	-	-	C	ko:K02124	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	ATP synthase subunit C
HOFPAOPE_01230	1.72e-31	atpF	-	-	C	ko:K02122	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Produces ATP from ADP in the presence of a proton gradient across the membrane
HOFPAOPE_01231	7.05e-317	ntpA	3.6.3.14, 3.6.3.15	-	C	ko:K02117	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
HOFPAOPE_01232	1.52e-288	atpB	-	-	C	ko:K02118	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
HOFPAOPE_01233	2.67e-93	atpD	-	-	C	ko:K02120	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Produces ATP from ADP in the presence of a proton gradient across the membrane
HOFPAOPE_01238	0.0	-	-	-	Q	-	-	-	Alkyl sulfatase dimerisation
HOFPAOPE_01239	2.09e-83	-	-	-	K	-	-	-	LytTr DNA-binding domain
HOFPAOPE_01240	2.7e-139	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_01241	4.39e-148	-	-	-	M	-	-	-	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
HOFPAOPE_01242	7.3e-230	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HOFPAOPE_01243	5.78e-33	plsD	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HOFPAOPE_01244	3.98e-26	-	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
HOFPAOPE_01245	5.15e-264	-	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HOFPAOPE_01246	2.14e-107	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HOFPAOPE_01247	5.15e-61	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	K02372 3R-hydroxymyristoyl ACP dehydrase
HOFPAOPE_01248	2.24e-85	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HOFPAOPE_01249	2.08e-13	-	-	-	K	-	-	-	transcriptional regulator
HOFPAOPE_01250	5.97e-70	-	-	-	S	-	-	-	esterase of the alpha-beta hydrolase superfamily
HOFPAOPE_01252	1.03e-70	-	-	-	K	-	-	-	Transcriptional regulator
HOFPAOPE_01254	3.57e-42	-	-	-	K	-	-	-	Sigma-70, region 4
HOFPAOPE_01255	0.000194	-	-	-	S	-	-	-	Putative zinc-finger
HOFPAOPE_01256	3.46e-54	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HOFPAOPE_01260	2.8e-147	dapL	2.6.1.83	-	E	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HOFPAOPE_01261	6.81e-29	dapL	2.6.1.83	-	E	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HOFPAOPE_01262	0.0	tetP	-	-	J	-	-	-	Elongation factor G, domain IV
HOFPAOPE_01263	8.22e-68	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HOFPAOPE_01264	1.65e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF436)
HOFPAOPE_01265	4.34e-283	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HOFPAOPE_01266	2.46e-61	-	-	-	S	-	-	-	Acyltransferase family
HOFPAOPE_01267	4.84e-46	nnrE	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HOFPAOPE_01268	1.1e-110	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HOFPAOPE_01270	5.79e-46	-	-	-	-	-	-	-	-
HOFPAOPE_01271	2.94e-20	-	-	-	-	-	-	-	-
HOFPAOPE_01272	2.31e-34	-	-	-	K	-	-	-	transcriptional regulator
HOFPAOPE_01273	4.49e-30	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_01274	0.0	copA_1	-	-	P	ko:K12950	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
HOFPAOPE_01275	1.07e-33	-	-	-	-	-	-	-	-
HOFPAOPE_01276	1.06e-121	-	-	-	P	ko:K07238	-	ko00000,ko02000	ZIP Zinc transporter
HOFPAOPE_01277	9.13e-114	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HOFPAOPE_01278	2.67e-100	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HOFPAOPE_01279	1.65e-38	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HOFPAOPE_01280	2.29e-104	-	-	-	E	-	-	-	branched-chain amino acid permease (Azaleucine resistance)
HOFPAOPE_01281	2.01e-23	-	-	-	T	-	-	-	Histidine kinase-like ATPase domain
HOFPAOPE_01282	6.01e-22	-	-	-	T	-	-	-	STAS domain
HOFPAOPE_01283	6.44e-103	-	-	-	V	-	-	-	MatE
HOFPAOPE_01284	0.0	-	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	TIGRFAM amino acid adenylation domain
HOFPAOPE_01285	2.33e-50	-	-	-	K	-	-	-	LytTr DNA-binding domain
HOFPAOPE_01286	9.05e-10	-	-	-	T	-	-	-	GHKL domain
HOFPAOPE_01287	5.79e-81	-	2.1.1.63	-	H	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HOFPAOPE_01289	4.31e-23	-	-	-	S	-	-	-	TM2 domain
HOFPAOPE_01290	3.68e-305	cysN	2.7.1.25, 2.7.7.4	-	H	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
HOFPAOPE_01291	6.92e-205	cysD	1.8.4.10, 1.8.4.8, 2.7.7.4	-	EH	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	PFAM Phosphoadenosine phosphosulfate reductase
HOFPAOPE_01292	4.76e-53	-	1.8.99.2	-	C	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	4 iron, 4 sulfur cluster binding
HOFPAOPE_01293	1.06e-312	aprA	1.8.99.2	-	C	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
HOFPAOPE_01294	5.49e-110	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HOFPAOPE_01295	5.86e-76	-	3.13.1.6	-	S	ko:K21140	ko04122,map04122	ko00000,ko00001,ko01000	Mov34 MPN PAD-1 family
HOFPAOPE_01296	1.36e-176	-	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	PFAM UBA THIF-type NAD FAD binding protein
HOFPAOPE_01297	4.36e-35	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	TIGRFAM thiamine biosynthesis protein ThiS
HOFPAOPE_01298	8.64e-41	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HOFPAOPE_01299	4.73e-47	-	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
HOFPAOPE_01300	6.27e-173	-	-	-	C	-	-	-	PFAM nitrite and sulphite reductase 4Fe-4S
HOFPAOPE_01301	4.05e-226	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HOFPAOPE_01302	6.35e-36	-	-	-	K	-	-	-	transcriptional regulator, Rrf2 family
HOFPAOPE_01303	2e-216	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	PFAM Aminotransferase class-III
HOFPAOPE_01304	1.45e-169	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
HOFPAOPE_01305	1.2e-158	cobA	1.3.1.76, 2.1.1.107, 4.2.1.75, 4.99.1.4	-	H	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HOFPAOPE_01306	2.41e-88	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HOFPAOPE_01307	2.09e-43	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Putative NAD(P)-binding
HOFPAOPE_01308	1.96e-102	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HOFPAOPE_01309	7.29e-140	thiF	-	-	H	ko:K22132	-	ko00000,ko03016	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HOFPAOPE_01310	1.94e-180	cysA	3.6.3.25	-	E	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HOFPAOPE_01311	6.11e-147	cysW	-	-	P	ko:K02047	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ATPase-coupled sulfate transmembrane transporter activity
HOFPAOPE_01312	2.32e-150	cysT	-	-	P	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfate ABC transporter, permease protein CysT
HOFPAOPE_01313	1.23e-189	sbp	-	-	P	ko:K02048	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Extracellular solute-binding protein
HOFPAOPE_01314	7.67e-111	rbr	-	-	C	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_01315	7.41e-185	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HOFPAOPE_01317	1.18e-186	-	-	-	V	-	-	-	CytoplasmicMembrane, score
HOFPAOPE_01318	3.38e-98	-	-	-	P	-	-	-	Voltage gated chloride channel
HOFPAOPE_01319	1.18e-197	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	PFAM Alpha amylase, catalytic
HOFPAOPE_01320	4.57e-121	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HOFPAOPE_01321	4.16e-257	adh	-	-	C	-	-	-	belongs to the iron- containing alcohol dehydrogenase family
HOFPAOPE_01322	7.08e-27	-	-	-	K	ko:K09681	-	ko00000,ko03000	LysR substrate binding domain
HOFPAOPE_01323	1.21e-170	-	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HOFPAOPE_01324	1.22e-256	-	-	-	IQ	-	-	-	AMP-binding enzyme C-terminal domain
HOFPAOPE_01325	5.09e-33	FcbC	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HOFPAOPE_01326	4.54e-51	glnB	-	-	K	ko:K04751,ko:K04752	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
HOFPAOPE_01327	4.3e-218	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
HOFPAOPE_01328	8.1e-233	rny	-	-	D	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HOFPAOPE_01329	1.28e-218	gap	1.2.1.12	-	C	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HOFPAOPE_01330	2.99e-281	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HOFPAOPE_01331	7.13e-192	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HOFPAOPE_01332	6.09e-116	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
HOFPAOPE_01333	8.07e-228	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HOFPAOPE_01334	3.35e-23	-	-	-	T	-	-	-	Pfam:DUF3816
HOFPAOPE_01335	1.88e-67	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HOFPAOPE_01336	9.71e-71	-	-	-	L	-	-	-	DNA alkylation repair enzyme
HOFPAOPE_01337	1.62e-96	-	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HOFPAOPE_01338	2.75e-118	-	-	-	M	-	-	-	group 2 family protein
HOFPAOPE_01340	1.67e-125	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HOFPAOPE_01341	3.75e-243	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
HOFPAOPE_01342	5.68e-79	yfbR	3.1.3.89	-	S	ko:K07023,ko:K08722	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	PFAM metal-dependent phosphohydrolase HD sub domain
HOFPAOPE_01343	6.86e-47	-	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator
HOFPAOPE_01344	6.22e-50	-	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HOFPAOPE_01345	1.31e-58	-	3.4.22.70	-	S	ko:K08600	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HOFPAOPE_01347	2.2e-155	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HOFPAOPE_01348	2.18e-166	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HOFPAOPE_01349	3.38e-179	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HOFPAOPE_01351	4.61e-106	pflX	1.97.1.4	-	C	ko:K04070	-	ko00000,ko01000	Radical SAM superfamily
HOFPAOPE_01352	1.09e-218	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HOFPAOPE_01353	8.53e-57	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HOFPAOPE_01354	1.5e-80	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HOFPAOPE_01355	2.14e-201	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HOFPAOPE_01356	7.48e-38	ziaR	-	-	K	ko:K21903	-	ko00000,ko03000	regulatory protein, arsR
HOFPAOPE_01357	4.11e-195	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
HOFPAOPE_01359	2.81e-279	ilvI	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	acetolactate synthase large subunit
HOFPAOPE_01360	1.43e-71	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetolactate synthase small
HOFPAOPE_01361	2.11e-223	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HOFPAOPE_01362	8.25e-60	-	-	-	G	-	-	-	Fibronectin type 3 domain
HOFPAOPE_01365	7.78e-72	yabE	-	-	S	-	-	-	G5 domain
HOFPAOPE_01366	1.95e-36	-	-	-	K	-	-	-	AraC-like ligand binding domain
HOFPAOPE_01367	5.06e-19	-	-	-	K	-	-	-	COG COG2207 AraC-type DNA-binding domain-containing proteins
HOFPAOPE_01368	6.42e-60	-	-	-	I	-	-	-	Carboxylesterase family
HOFPAOPE_01369	9.02e-20	-	-	-	N	-	-	-	Leucine rich repeats (6 copies)
HOFPAOPE_01370	2.9e-32	-	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	PFAM Bacterial regulatory proteins, crp family
HOFPAOPE_01371	4.93e-252	leuC	4.2.1.33, 4.2.1.35, 4.2.1.85	-	E	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HOFPAOPE_01372	2.94e-94	leuD	4.2.1.33, 4.2.1.35, 4.2.1.85	-	E	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HOFPAOPE_01373	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HOFPAOPE_01374	5.79e-232	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HOFPAOPE_01375	2.64e-44	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HOFPAOPE_01376	2.5e-71	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HOFPAOPE_01377	3.64e-50	mtnN	3.2.2.9	-	F	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HOFPAOPE_01378	1.69e-247	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	acetolactate synthase large subunit
HOFPAOPE_01379	2.09e-176	uraA	-	-	F	ko:K02824	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HOFPAOPE_01380	2.08e-116	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HOFPAOPE_01381	7.14e-50	-	-	-	KT	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_01383	6.81e-94	-	-	-	N	-	-	-	ABC-type uncharacterized transport system
HOFPAOPE_01384	3.23e-60	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HOFPAOPE_01385	5.01e-129	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
HOFPAOPE_01386	1.41e-47	spoVAE	-	-	S	ko:K06407	-	ko00000	Stage V sporulation protein AE
HOFPAOPE_01388	4.82e-168	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
HOFPAOPE_01389	5.54e-132	-	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HOFPAOPE_01390	9.13e-44	-	-	-	S	-	-	-	GtrA-like protein
HOFPAOPE_01391	6.25e-83	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HOFPAOPE_01392	1.56e-69	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HOFPAOPE_01393	4.33e-30	-	-	-	T	-	-	-	protein histidine kinase activity
HOFPAOPE_01399	7.86e-134	glcK	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HOFPAOPE_01400	3.41e-284	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HOFPAOPE_01402	1.88e-28	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_01403	9.38e-24	-	-	-	S	-	-	-	Domain of unknown function (DUF4234)
HOFPAOPE_01404	2.8e-266	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HOFPAOPE_01405	2.57e-107	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HOFPAOPE_01406	1.62e-126	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Cobyrinic acid ac-diamide synthase
HOFPAOPE_01407	1.62e-95	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HOFPAOPE_01408	2.05e-85	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HOFPAOPE_01409	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HOFPAOPE_01410	7.8e-196	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HOFPAOPE_01411	2.4e-91	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HOFPAOPE_01412	1.65e-80	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
HOFPAOPE_01413	2.43e-35	yidD	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HOFPAOPE_01414	1.37e-38	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HOFPAOPE_01415	9.02e-18	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HOFPAOPE_01416	4.13e-199	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HOFPAOPE_01417	7.17e-141	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HOFPAOPE_01418	6.04e-25	-	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HOFPAOPE_01419	4.05e-122	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HOFPAOPE_01420	4.52e-31	-	-	-	S	-	-	-	Domain of unknown function (DUF370)
HOFPAOPE_01422	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOFPAOPE_01423	3.94e-40	FcbC	-	-	S	ko:K07107	-	ko00000,ko01000	acyl-CoA thioester hydrolase
HOFPAOPE_01424	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOFPAOPE_01426	9.65e-112	-	-	-	-	-	-	-	-
HOFPAOPE_01427	1.04e-220	-	-	-	KT	-	-	-	response regulator
HOFPAOPE_01428	2.07e-220	apu	2.4.1.25, 3.2.1.133, 3.2.1.135, 3.2.1.20, 3.2.1.54	GH13,GH31,GH77	G	ko:K00705,ko:K01187,ko:K01208	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HOFPAOPE_01430	5.15e-188	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Evidence 5 No homology to any previously reported sequences
HOFPAOPE_01431	2.65e-59	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HOFPAOPE_01432	1.77e-184	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein, MreB Mrl family
HOFPAOPE_01433	1.6e-53	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Cell shape-determining protein MreC
HOFPAOPE_01435	3.35e-177	mrdA	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HOFPAOPE_01436	9.46e-58	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HOFPAOPE_01437	4.36e-85	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HOFPAOPE_01438	4.88e-200	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HOFPAOPE_01439	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HOFPAOPE_01440	8.79e-44	-	-	-	-	-	-	-	-
HOFPAOPE_01441	2.95e-145	-	-	-	S	-	-	-	SPFH domain-Band 7 family
HOFPAOPE_01442	1.33e-99	-	-	-	S	-	-	-	bacterial-type flagellum-dependent swarming motility
HOFPAOPE_01444	6.68e-157	hydE	2.8.1.6	-	C	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	radical SAM domain protein
HOFPAOPE_01445	2.23e-271	hydG	4.1.99.19	-	C	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	biosynthesis protein ThiH
HOFPAOPE_01446	6.1e-177	hydF	-	-	S	-	-	-	small GTP-binding protein
HOFPAOPE_01447	2.59e-222	-	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	AMP-dependent synthetase and ligase
HOFPAOPE_01448	9.75e-124	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HOFPAOPE_01449	2.46e-148	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HOFPAOPE_01450	8.79e-215	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HOFPAOPE_01451	2.01e-89	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HOFPAOPE_01452	1.95e-142	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HOFPAOPE_01453	2.93e-113	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
HOFPAOPE_01454	1.36e-241	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HOFPAOPE_01455	1.27e-126	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HOFPAOPE_01456	3.03e-130	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HOFPAOPE_01457	1.65e-27	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HOFPAOPE_01459	1.34e-16	-	-	-	-	-	-	-	-
HOFPAOPE_01460	2.5e-47	-	-	-	S	ko:K18475	-	ko00000,ko01000,ko02035	N-methylation of lysine residues in flagellin K00599
HOFPAOPE_01461	2.99e-143	-	-	-	T	-	-	-	Histidine kinase
HOFPAOPE_01462	4.07e-126	-	-	-	K	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HOFPAOPE_01463	7.13e-144	-	4.2.1.2	-	C	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type
HOFPAOPE_01464	3.25e-94	fumB	4.2.1.2	-	C	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Hydrolyase, tartrate beta subunit fumarate domain protein, Fe-S type
HOFPAOPE_01466	9.68e-54	-	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Nudix hydrolase
HOFPAOPE_01467	1.73e-86	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HOFPAOPE_01468	4.68e-113	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HOFPAOPE_01470	1.81e-82	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HOFPAOPE_01471	4.64e-45	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HOFPAOPE_01472	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HOFPAOPE_01473	3.22e-190	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HOFPAOPE_01474	2.18e-144	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HOFPAOPE_01476	9.11e-129	mrp	-	-	D	-	-	-	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HOFPAOPE_01479	4.42e-38	-	-	-	K	-	-	-	sequence-specific DNA binding
HOFPAOPE_01480	5.94e-90	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HOFPAOPE_01481	1.96e-97	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HOFPAOPE_01482	3.13e-62	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_01484	2.52e-167	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HOFPAOPE_01485	9.34e-170	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HOFPAOPE_01486	9.44e-44	-	2.3.1.1	-	K	ko:K22477	ko00220,ko01210,ko01230,map00220,map01210,map01230	ko00000,ko00001,ko00002,ko01000	GCN5 family acetyltransferase
HOFPAOPE_01487	6.22e-150	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HOFPAOPE_01488	2.12e-181	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HOFPAOPE_01489	2.02e-183	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HOFPAOPE_01490	3.27e-230	argH	2.3.1.1, 4.3.2.1	-	E	ko:K01755,ko:K14681	ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HOFPAOPE_01491	2.34e-240	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HOFPAOPE_01492	1.81e-69	-	-	-	S	ko:K18843	-	ko00000,ko02048	HicB family
HOFPAOPE_01493	2.86e-65	-	-	-	S	-	-	-	Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family
HOFPAOPE_01494	3.25e-177	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha-amylase domain
HOFPAOPE_01495	6.95e-76	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HOFPAOPE_01496	7.38e-74	-	-	-	T	-	-	-	response regulator receiver
HOFPAOPE_01497	3.81e-108	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HOFPAOPE_01498	3.82e-112	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HOFPAOPE_01499	4.2e-103	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HOFPAOPE_01500	6.57e-98	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
HOFPAOPE_01501	2.54e-53	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HOFPAOPE_01502	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HOFPAOPE_01503	7.21e-17	ylxRQ	-	-	J	ko:K07590,ko:K07742	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ncRNA processing
HOFPAOPE_01504	1.11e-38	ylxR	-	-	K	ko:K07742	-	ko00000	Nucleic-acid-binding protein implicated in transcription termination
HOFPAOPE_01505	1.95e-153	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HOFPAOPE_01506	1.5e-62	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HOFPAOPE_01508	5.56e-34	-	-	-	S	-	-	-	Domain of unknown function (DUF4258)
HOFPAOPE_01509	7.23e-22	-	-	-	S	-	-	-	YgiT-type zinc finger domain protein
HOFPAOPE_01510	3.41e-27	-	-	-	-	-	-	-	-
HOFPAOPE_01512	1.54e-33	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
HOFPAOPE_01513	1.22e-150	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_01514	7.42e-202	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_01515	1.87e-16	-	-	-	S	-	-	-	CpXC protein
HOFPAOPE_01517	0.0	hgdC2	-	-	I	-	-	-	CoA-substrate-specific enzyme activase
HOFPAOPE_01518	4.32e-203	-	-	-	I	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_01519	5.64e-89	-	-	-	-	-	-	-	-
HOFPAOPE_01520	1.1e-74	htrA	3.4.21.107	-	O	ko:K04771,ko:K08372	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	smart pdz dhr glgf
HOFPAOPE_01521	1.37e-187	fba	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HOFPAOPE_01522	1.32e-52	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HOFPAOPE_01524	5.74e-17	-	-	-	S	-	-	-	Toxin ToxN, type III toxin-antitoxin system
HOFPAOPE_01525	9.19e-180	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HOFPAOPE_01526	5.86e-153	-	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin binding
HOFPAOPE_01527	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HOFPAOPE_01530	2.88e-67	-	-	-	M	-	-	-	Sortase family
HOFPAOPE_01531	5.69e-37	-	-	-	M	-	-	-	Sortase family
HOFPAOPE_01533	0.000545	-	-	-	L	ko:K07497	-	ko00000	Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HOFPAOPE_01535	3.64e-115	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HOFPAOPE_01536	2.4e-94	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HOFPAOPE_01537	1.06e-138	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HOFPAOPE_01538	4.21e-66	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	transport system, ATPase component
HOFPAOPE_01539	5.97e-72	-	-	-	T	-	-	-	sensory transduction histidine kinases K07706
HOFPAOPE_01540	2.23e-35	-	-	-	KT	-	-	-	response regulator
HOFPAOPE_01541	1.82e-49	-	-	-	L	-	-	-	Resolvase, N terminal domain
HOFPAOPE_01544	4.64e-95	-	-	-	L	-	-	-	Transposase
HOFPAOPE_01547	2.31e-152	-	-	-	T	-	-	-	domain protein
HOFPAOPE_01548	2.34e-107	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_01549	6.5e-39	-	-	-	S	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HOFPAOPE_01550	5.1e-37	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HOFPAOPE_01554	5.19e-283	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
HOFPAOPE_01555	5.6e-290	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Hsp90 protein
HOFPAOPE_01556	5.61e-152	-	-	-	M	-	-	-	Sulfatase
HOFPAOPE_01557	3.04e-38	-	-	-	D	-	-	-	protein involved in cytokinesis, contains TGc (transglutaminase protease-like) domain
HOFPAOPE_01558	9.65e-43	-	-	-	D	-	-	-	Transglutaminase-like superfamily
HOFPAOPE_01559	1.51e-93	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HOFPAOPE_01560	2.29e-173	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HOFPAOPE_01561	4.48e-63	-	-	-	S	-	-	-	membrane
HOFPAOPE_01562	1.83e-270	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Galactose mutarotase-like
HOFPAOPE_01563	2.29e-33	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HOFPAOPE_01564	2.97e-246	-	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HOFPAOPE_01565	3.42e-38	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HOFPAOPE_01566	2.31e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF1292)
HOFPAOPE_01568	1.93e-204	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HOFPAOPE_01573	5.85e-172	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOFPAOPE_01574	8.14e-307	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HOFPAOPE_01575	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HOFPAOPE_01576	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HOFPAOPE_01577	2.33e-265	amt	-	-	EP	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
HOFPAOPE_01578	4.8e-38	-	-	-	-	ko:K07726	-	ko00000,ko03000	-
HOFPAOPE_01579	1.06e-89	-	-	-	-	-	-	-	-
HOFPAOPE_01580	1.12e-35	-	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	ANTAR domain protein
HOFPAOPE_01581	1.87e-184	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HOFPAOPE_01582	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HOFPAOPE_01583	3.33e-295	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HOFPAOPE_01584	5.24e-206	dapL	2.6.1.83	-	H	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate
HOFPAOPE_01585	2.38e-309	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HOFPAOPE_01587	9.93e-45	-	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
HOFPAOPE_01588	6.96e-61	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	phosphoglycolate phosphatase, bacterial
HOFPAOPE_01589	1.24e-93	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HOFPAOPE_01590	4.3e-240	ptsP	2.7.3.9, 2.7.9.2	-	G	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HOFPAOPE_01591	5.87e-35	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	HPr family
HOFPAOPE_01592	9.11e-267	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system
HOFPAOPE_01593	4.08e-126	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HOFPAOPE_01594	1.8e-88	fruR	-	-	GK	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HOFPAOPE_01595	9.28e-44	-	-	-	K	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HOFPAOPE_01596	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HOFPAOPE_01597	2.71e-90	nrdG	1.97.1.4	-	C	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HOFPAOPE_01598	1.5e-13	-	-	-	-	-	-	-	-
HOFPAOPE_01599	1.1e-221	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HOFPAOPE_01600	7.81e-182	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HOFPAOPE_01601	7.08e-191	mrcB	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HOFPAOPE_01603	1.59e-142	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HOFPAOPE_01604	2.17e-126	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
HOFPAOPE_01605	7.96e-114	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HOFPAOPE_01606	2.2e-187	fabF	2.3.1.179, 2.3.1.41	-	I	ko:K00647,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HOFPAOPE_01607	5.98e-32	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HOFPAOPE_01608	2.66e-62	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HOFPAOPE_01609	6.41e-220	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	acetyl-CoA carboxylase, biotin carboxylase
HOFPAOPE_01610	2.44e-125	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HOFPAOPE_01611	3.81e-130	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HOFPAOPE_01613	1.21e-239	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.87
HOFPAOPE_01614	2.35e-42	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_01617	8.22e-21	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HOFPAOPE_01619	2.93e-277	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
HOFPAOPE_01620	2.4e-12	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HOFPAOPE_01621	2.09e-111	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HOFPAOPE_01622	6.72e-55	-	-	-	-	-	-	-	-
HOFPAOPE_01623	1.22e-26	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HOFPAOPE_01625	6.72e-84	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HOFPAOPE_01626	2.78e-83	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HOFPAOPE_01627	3.35e-135	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HOFPAOPE_01628	6.67e-46	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HOFPAOPE_01629	2.77e-48	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HOFPAOPE_01630	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HOFPAOPE_01631	6.56e-96	-	-	-	S	-	-	-	type ii restriction enzyme
HOFPAOPE_01633	2.05e-11	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_01634	1.15e-32	-	-	-	S	-	-	-	Putative esterase
HOFPAOPE_01635	1.63e-60	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HOFPAOPE_01636	6.4e-10	-	-	-	S	-	-	-	YcxB-like protein
HOFPAOPE_01637	4.62e-96	-	2.3.1.8	-	Q	ko:K15024	ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HOFPAOPE_01638	5.31e-108	udgA	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HOFPAOPE_01639	1.21e-115	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC-type antimicrobial peptide transport system, ATPase component
HOFPAOPE_01640	1.92e-174	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Permease
HOFPAOPE_01641	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HOFPAOPE_01642	3.49e-22	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOFPAOPE_01643	2.17e-244	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HOFPAOPE_01644	9.48e-223	gatB	6.1.1.12, 6.3.5.6, 6.3.5.7	-	J	ko:K01876,ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOFPAOPE_01646	6.3e-295	trpB	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HOFPAOPE_01647	2.8e-97	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	phosphate binding protein
HOFPAOPE_01648	5.64e-134	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HOFPAOPE_01649	7.68e-124	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate transport system permease
HOFPAOPE_01650	2.61e-146	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HOFPAOPE_01651	4.65e-64	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HOFPAOPE_01652	1.48e-89	phoB	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HOFPAOPE_01653	1.26e-121	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HOFPAOPE_01654	7.85e-230	-	-	-	P	ko:K03324	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HOFPAOPE_01655	1.57e-92	-	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HOFPAOPE_01656	1.52e-128	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HOFPAOPE_01657	8.2e-65	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HOFPAOPE_01658	0.0	hcp	1.7.99.1	-	C	ko:K05601	ko00910,map00910	ko00000,ko00001,ko01000	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O
HOFPAOPE_01659	3.86e-43	mprF	-	-	M	ko:K07027	-	ko00000,ko02000	lysyltransferase activity
HOFPAOPE_01660	2.87e-91	-	-	-	-	-	-	-	-
HOFPAOPE_01662	5.72e-50	-	-	-	S	-	-	-	Domain in cystathionine beta-synthase and other proteins.
HOFPAOPE_01663	1.88e-80	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HOFPAOPE_01664	2.75e-37	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HOFPAOPE_01666	2.44e-94	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
HOFPAOPE_01669	5.31e-106	ytrB	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HOFPAOPE_01670	4.17e-38	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HOFPAOPE_01671	6.97e-142	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HOFPAOPE_01672	1.19e-33	-	-	-	S	-	-	-	protein, YerC YecD
HOFPAOPE_01673	5.68e-91	-	-	-	Q	-	-	-	Methyltransferase domain protein
HOFPAOPE_01674	8.56e-117	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HOFPAOPE_01680	1.4e-159	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HOFPAOPE_01681	7.14e-106	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HOFPAOPE_01682	3.83e-67	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Carbohydrate kinase
HOFPAOPE_01683	4.74e-147	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Carbohydrate kinase
HOFPAOPE_01684	2.49e-195	cytX	-	-	F	-	-	-	COG COG1457 Purine-cytosine permease and related proteins
HOFPAOPE_01685	1.29e-258	-	-	-	S	ko:K06921	-	ko00000	ATPase domain predominantly from Archaea
HOFPAOPE_01686	1.65e-82	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein T
HOFPAOPE_01687	1.07e-24	-	-	-	O	-	-	-	regulation of methylation-dependent chromatin silencing
HOFPAOPE_01688	3.97e-84	-	-	-	Q	-	-	-	Isochorismatase family
HOFPAOPE_01689	1.9e-96	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HOFPAOPE_01690	7.69e-294	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HOFPAOPE_01691	2.68e-142	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HOFPAOPE_01692	1.71e-44	-	-	-	-	-	-	-	-
HOFPAOPE_01693	0.0	kdpD	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HOFPAOPE_01694	8.35e-164	kdpE	-	-	KT	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HOFPAOPE_01699	4.17e-169	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HOFPAOPE_01701	1.86e-81	spoVFA	-	-	EH	ko:K06410	-	ko00000	4-phosphoerythronate dehydrogenase activity
HOFPAOPE_01702	3.54e-82	spoVFB	-	-	H	ko:K06411	-	ko00000	Flavoprotein
HOFPAOPE_01704	9.75e-26	-	-	-	K	-	-	-	transcriptional regulator
HOFPAOPE_01707	3.39e-245	-	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
HOFPAOPE_01708	3.21e-57	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HOFPAOPE_01709	3.69e-74	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HOFPAOPE_01710	1.25e-148	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HOFPAOPE_01711	1.65e-256	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HOFPAOPE_01712	8.04e-54	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_01714	2.93e-72	-	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Cytidylate kinase-like family
HOFPAOPE_01718	7.33e-10	wprA	-	-	O	-	-	-	Belongs to the peptidase S8 family
HOFPAOPE_01721	4.17e-210	-	-	-	L	-	-	-	Transposase, mutator
HOFPAOPE_01722	5.89e-87	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
HOFPAOPE_01725	1.71e-23	-	-	-	M	-	-	-	RHS repeat-associated core domain
HOFPAOPE_01726	1.12e-36	-	-	-	M	-	-	-	YD repeat (two copies)
HOFPAOPE_01728	8.01e-26	-	-	-	OU	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_01729	2.31e-28	qmcA	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
HOFPAOPE_01730	7.67e-274	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HOFPAOPE_01731	9.67e-33	-	-	-	V	-	-	-	Beta-lactamase
HOFPAOPE_01733	1.59e-39	-	-	-	M	-	-	-	RHS repeat-associated core domain
HOFPAOPE_01735	8.69e-27	-	-	-	OU	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_01736	7.53e-123	qmcA	-	-	O	-	-	-	SPFH domain Band 7 family
HOFPAOPE_01737	2.96e-77	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HOFPAOPE_01738	3.34e-75	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HOFPAOPE_01739	1.14e-170	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HOFPAOPE_01740	1.22e-184	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HOFPAOPE_01741	2.65e-95	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HOFPAOPE_01742	4.78e-129	-	-	-	F	-	-	-	IMP cyclohydrolase-like protein
HOFPAOPE_01743	2.33e-239	purH2	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT IMPCHase bienzyme
HOFPAOPE_01744	5.4e-226	purD	6.3.2.6, 6.3.4.13	-	F	ko:K01945,ko:K13713	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HOFPAOPE_01745	1.21e-108	spo0A	-	-	NT	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HOFPAOPE_01746	6.2e-77	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
HOFPAOPE_01747	7.65e-230	-	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HOFPAOPE_01748	4.53e-127	cca	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	tRNA nucleotidyltransferase poly(A) polymerase
HOFPAOPE_01749	2.06e-123	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HOFPAOPE_01750	5.28e-169	ArtM	-	-	E	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HOFPAOPE_01751	2.77e-213	-	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HOFPAOPE_01752	1.01e-142	-	-	-	G	-	-	-	hydrolase activity, hydrolyzing O-glycosyl compounds
HOFPAOPE_01753	1.67e-199	-	-	-	S	ko:K07137	-	ko00000	'oxidoreductase
HOFPAOPE_01754	2.52e-89	-	-	-	S	ko:K07007	-	ko00000	HI0933 family
HOFPAOPE_01755	1.12e-70	-	-	-	S	-	-	-	small multi-drug export protein
HOFPAOPE_01756	3.72e-24	-	-	-	S	-	-	-	VanZ like family
HOFPAOPE_01757	5.12e-157	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_01759	0.000436	-	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Belongs to the peptidase M50B family
HOFPAOPE_01760	0.0	-	-	-	C	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HOFPAOPE_01761	4.2e-66	-	-	-	C	-	-	-	Protein conserved in bacteria
HOFPAOPE_01763	2.75e-127	ytqA	-	-	S	ko:K07139	-	ko00000	radical SAM protein, TIGR01212 family
HOFPAOPE_01766	1.89e-136	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HOFPAOPE_01767	2.07e-78	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HOFPAOPE_01768	5.2e-115	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HOFPAOPE_01769	1.23e-47	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Psort location CytoplasmicMembrane, score 10.00
HOFPAOPE_01770	1.3e-167	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HOFPAOPE_01771	1.22e-105	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Metalloprotease
HOFPAOPE_01772	5.12e-186	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HOFPAOPE_01773	0.0	polC	2.7.7.7	-	L	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HOFPAOPE_01774	6.94e-74	yhhT	-	-	S	-	-	-	hmm pf01594
HOFPAOPE_01775	3.48e-134	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HOFPAOPE_01776	2.99e-107	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HOFPAOPE_01777	1.02e-211	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HOFPAOPE_01778	5.12e-125	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HOFPAOPE_01779	3.76e-87	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HOFPAOPE_01780	4.3e-97	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HOFPAOPE_01781	1.36e-60	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HOFPAOPE_01782	3.11e-54	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP
HOFPAOPE_01784	2.51e-167	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	tRNA methylthiotransferase YqeV
HOFPAOPE_01785	4.52e-111	-	-	-	S	-	-	-	Glycosyl hydrolase-like 10
HOFPAOPE_01786	5.34e-18	ysdA	-	-	L	-	-	-	Membrane
HOFPAOPE_01787	7.43e-76	rluD_2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HOFPAOPE_01791	1.77e-110	-	-	-	V	-	-	-	ABC transporter
HOFPAOPE_01792	2.01e-19	-	-	-	M	-	-	-	PFAM Chain length determinant protein
HOFPAOPE_01793	8.57e-43	-	-	-	D	-	-	-	Capsular exopolysaccharide family
HOFPAOPE_01794	7.17e-94	cpsE	-	-	M	-	-	-	sugar transferase
HOFPAOPE_01795	3.37e-250	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HOFPAOPE_01796	4.7e-147	-	2.7.1.168	-	S	ko:K07031	ko00540,map00540	ko00000,ko00001,ko01000	GHMP kinases C terminal
HOFPAOPE_01797	8.96e-106	-	-	-	V	-	-	-	ABC transporter
HOFPAOPE_01800	1.36e-78	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HOFPAOPE_01801	5.99e-21	-	-	-	T	-	-	-	Histidine kinase
HOFPAOPE_01802	5.68e-24	-	-	-	T	-	-	-	LytTr DNA-binding domain
HOFPAOPE_01803	5.65e-99	mro	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HOFPAOPE_01804	2.88e-233	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, C-terminal domain
HOFPAOPE_01805	2.28e-196	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HOFPAOPE_01806	1.32e-189	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family
HOFPAOPE_01807	6.65e-234	lacS	-	-	G	ko:K03292,ko:K11104,ko:K16209	-	ko00000,ko02000	Vacuole effluxer Atg22 like
HOFPAOPE_01808	1.93e-114	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score
HOFPAOPE_01809	4.33e-149	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HOFPAOPE_01810	3.45e-113	-	-	-	-	-	-	-	-
HOFPAOPE_01811	5.1e-114	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 7.50
HOFPAOPE_01813	3.05e-12	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HOFPAOPE_01814	2.22e-118	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
HOFPAOPE_01816	6.09e-07	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
HOFPAOPE_01819	1.41e-72	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain
HOFPAOPE_01820	3.01e-85	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	chromosome partitioning protein K03497
HOFPAOPE_01824	1.61e-48	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HOFPAOPE_01825	3.35e-18	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HOFPAOPE_01826	2.45e-40	-	-	-	M	-	-	-	Psort location Cellwall, score
HOFPAOPE_01827	0.000833	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HOFPAOPE_01828	5.3e-71	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HOFPAOPE_01829	1.82e-76	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Universal bacterial protein YeaZ
HOFPAOPE_01830	4.72e-61	yjeE	2.7.1.221	-	S	ko:K06925,ko:K07102	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
HOFPAOPE_01831	2.12e-312	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HOFPAOPE_01832	3.27e-115	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HOFPAOPE_01833	1.65e-09	-	-	-	S	-	-	-	YbbR-like protein
HOFPAOPE_01834	5.73e-81	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HOFPAOPE_01835	1.31e-134	-	-	-	E	-	-	-	cysteine desulfurase family protein
HOFPAOPE_01837	8.72e-106	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HOFPAOPE_01838	1.3e-130	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HOFPAOPE_01839	2.49e-201	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartate-semialdehyde dehydrogenase family
HOFPAOPE_01840	1.45e-179	queA	2.4.99.17	-	H	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HOFPAOPE_01841	2.36e-214	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HOFPAOPE_01842	3.16e-21	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
HOFPAOPE_01844	1.13e-14	-	-	-	P	-	-	-	YARHG
HOFPAOPE_01846	2.41e-280	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HOFPAOPE_01847	3.4e-20	-	-	-	L	ko:K07485	-	ko00000	Transposase
HOFPAOPE_01849	3.11e-30	-	-	-	S	-	-	-	Antidote-toxin recognition MazE, bacterial antitoxin
HOFPAOPE_01850	5.7e-70	vapC	-	-	S	-	-	-	Toxic component of a toxin-antitoxin (TA) module. An RNase
HOFPAOPE_01851	1.44e-24	-	-	-	-	-	-	-	-
HOFPAOPE_01852	5.04e-48	-	-	-	S	-	-	-	Peptidase_C39 like family
HOFPAOPE_01854	2.36e-09	-	-	-	M	-	-	-	self proteolysis
HOFPAOPE_01856	3.61e-57	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_01857	5.78e-79	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HOFPAOPE_01858	1.21e-194	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HOFPAOPE_01859	8.21e-139	alr	5.1.1.1, 5.1.1.18	-	M	ko:K01775,ko:K18348	ko00473,ko01100,ko01502,ko02020,map00473,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HOFPAOPE_01860	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOFPAOPE_01861	1.22e-26	-	3.1.3.48, 5.3.1.6	-	T	ko:K01104,ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Low molecular weight phosphatase family
HOFPAOPE_01862	1.08e-39	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HOFPAOPE_01863	5.55e-179	tsaD	2.3.1.234	-	O	ko:K01409,ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HOFPAOPE_01864	3.82e-105	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HOFPAOPE_01865	1.91e-171	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HOFPAOPE_01870	3.37e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HOFPAOPE_01871	1.88e-74	-	-	-	S	-	-	-	peptidase M50
HOFPAOPE_01872	4.87e-86	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HOFPAOPE_01873	4.41e-69	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HOFPAOPE_01874	1.04e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF2953)
HOFPAOPE_01875	6.11e-47	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HOFPAOPE_01876	3.1e-101	-	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HOFPAOPE_01877	5.02e-103	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HOFPAOPE_01878	4.16e-117	mdcD	2.1.3.10, 4.1.1.87	-	I	ko:K13932,ko:K13933,ko:K20510,ko:K20511	-	ko00000,ko01000,ko02000	CoA carboxylase activity
HOFPAOPE_01879	2.73e-15	gcdC	-	-	I	-	-	-	Biotin-requiring enzyme
HOFPAOPE_01880	9.36e-276	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Pyruvate carboxylase, C-terminal domain subunit K01960
HOFPAOPE_01882	7.96e-20	-	-	-	L	-	-	-	COG COG3328 Transposase and inactivated derivatives
HOFPAOPE_01886	0.000486	-	-	-	-	-	-	-	-
HOFPAOPE_01887	3.97e-39	-	-	-	S	-	-	-	YjcQ protein
HOFPAOPE_01888	1.14e-53	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_01889	1.74e-46	-	-	-	T	-	-	-	Psort location
HOFPAOPE_01890	1.59e-82	-	-	-	T	ko:K07694	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator receiver domain protein
HOFPAOPE_01893	4.97e-56	-	-	-	-	-	-	-	-
HOFPAOPE_01895	5.69e-34	-	-	-	S	-	-	-	Domain of unknown function (DUF4428)
HOFPAOPE_01897	1.44e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF5131)
HOFPAOPE_01898	1.15e-242	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase (RecQ)
HOFPAOPE_01899	4.78e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
HOFPAOPE_01900	2.24e-159	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HOFPAOPE_01901	1.87e-29	rubR2	-	-	C	-	-	-	rubredoxin
HOFPAOPE_01902	1.32e-95	rbr3A	-	-	C	-	-	-	Psort location Cytoplasmic, score
HOFPAOPE_01903	1.38e-40	fur	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	belongs to the Fur family
HOFPAOPE_01904	3.09e-83	-	-	-	G	-	-	-	PFAM Polysaccharide deacetylase
HOFPAOPE_01905	6.93e-46	-	-	-	M	-	-	-	O-Antigen ligase
HOFPAOPE_01906	2.66e-31	-	3.1.3.18	-	F	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HOFPAOPE_01907	1.91e-10	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HOFPAOPE_01912	9.19e-108	-	-	-	V	-	-	-	ABC transporter
HOFPAOPE_01915	5.62e-06	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC-type antimicrobial peptide transport system, permease component
HOFPAOPE_01917	4.08e-90	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC-type sugar transport system, permease component
HOFPAOPE_01918	1.21e-76	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HOFPAOPE_01921	2.08e-06	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HOFPAOPE_01922	1.41e-13	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	carbohydrate transport
HOFPAOPE_01923	8.92e-09	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HOFPAOPE_01924	4.5e-41	-	-	-	T	ko:K02477	-	ko00000,ko02022	LytTr DNA-binding domain
HOFPAOPE_01925	6.3e-36	-	-	-	T	-	-	-	GHKL domain
HOFPAOPE_01926	8.07e-226	-	-	-	S	-	-	-	Domain of unknown function (DUF4143)
HOFPAOPE_01927	4.56e-28	qmcA	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
HOFPAOPE_01928	1.64e-19	-	-	-	OU	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_01930	2.77e-66	-	-	-	M	-	-	-	RHS repeat-associated core domain
HOFPAOPE_01931	1.73e-130	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_01933	1.07e-54	spmB	-	-	S	ko:K06374	-	ko00000	Nucleoside recognition
HOFPAOPE_01934	1.71e-58	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
HOFPAOPE_01936	9.24e-83	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
HOFPAOPE_01937	3.81e-17	-	-	-	H	-	-	-	4'-phosphopantetheinyl transferase superfamily
HOFPAOPE_01938	2.1e-59	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOFPAOPE_01939	0.0	-	-	-	S	ko:K07003	-	ko00000	Psort location CytoplasmicMembrane, score
HOFPAOPE_01940	4.42e-112	-	-	-	S	ko:K01421	-	ko00000	Psort location Cellwall, score
HOFPAOPE_01941	4.64e-29	-	-	-	S	-	-	-	Small, acid-soluble spore protein, alpha beta type
HOFPAOPE_01942	1.2e-195	-	-	-	S	-	-	-	Domain of unknown function (DUF4143)
HOFPAOPE_01944	1.43e-281	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HOFPAOPE_01945	4.91e-217	-	-	-	K	-	-	-	WYL domain
HOFPAOPE_01946	2.24e-153	srtB	-	-	S	-	-	-	sortase, SrtB family
HOFPAOPE_01947	7.37e-39	-	-	-	-	-	-	-	-
HOFPAOPE_01948	0.0	-	3.2.1.78	GH26	U	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	domain, Protein
HOFPAOPE_01949	3.43e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HOFPAOPE_01950	9.26e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
HOFPAOPE_01951	3.39e-12	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HOFPAOPE_01953	1.42e-11	-	-	-	KT	-	-	-	response regulator
HOFPAOPE_01955	4.79e-07	-	-	-	-	-	-	-	-
HOFPAOPE_01956	1.44e-155	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HOFPAOPE_01957	2.15e-162	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HOFPAOPE_01965	1.69e-08	-	-	-	L	-	-	-	Resolvase, N terminal domain
HOFPAOPE_01966	1.77e-44	-	-	-	L	-	-	-	Psort location Cytoplasmic, score