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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MACFILCD_00002	3.81e-228	-	-	-	S	-	-	-	Protein of unknown function (DUF1194)
MACFILCD_00003	8.06e-134	-	-	-	-	-	-	-	-
MACFILCD_00004	4.38e-211	-	-	-	S	-	-	-	Protein of unknown function DUF58
MACFILCD_00005	2.48e-228	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
MACFILCD_00006	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MACFILCD_00007	5.79e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MACFILCD_00009	2.63e-10	-	-	-	-	-	-	-	-
MACFILCD_00011	3.57e-280	-	-	-	S	-	-	-	Tetratricopeptide repeat
MACFILCD_00012	0.0	-	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
MACFILCD_00013	6.2e-203	-	-	-	-	-	-	-	-
MACFILCD_00014	4.04e-240	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
MACFILCD_00015	5.63e-177	-	-	-	O	-	-	-	Trypsin
MACFILCD_00018	8.22e-290	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
MACFILCD_00019	4.68e-192	-	-	-	KT	-	-	-	Peptidase S24-like
MACFILCD_00021	2.29e-141	-	-	-	M	-	-	-	polygalacturonase activity
MACFILCD_00022	5.92e-303	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
MACFILCD_00023	1.71e-239	-	1.2.7.3	-	-	ko:K00176,ko:K07138	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	-
MACFILCD_00024	1.93e-207	-	-	-	S	-	-	-	Aldo/keto reductase family
MACFILCD_00025	2.97e-268	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
MACFILCD_00026	5.16e-271	-	-	-	C	-	-	-	Aldo/keto reductase family
MACFILCD_00027	3.6e-265	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
MACFILCD_00028	1.17e-127	-	-	-	C	-	-	-	FMN binding
MACFILCD_00029	2.82e-100	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
MACFILCD_00030	6.4e-188	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
MACFILCD_00031	4.8e-128	-	-	-	S	-	-	-	Flavodoxin-like fold
MACFILCD_00032	2.29e-112	-	-	-	K	ko:K13640	-	ko00000,ko03000	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MACFILCD_00033	3.52e-102	-	-	-	G	-	-	-	single-species biofilm formation
MACFILCD_00034	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
MACFILCD_00035	0.0	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
MACFILCD_00037	7.43e-55	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MACFILCD_00038	1.09e-121	-	-	-	D	-	-	-	MobA MobL family protein
MACFILCD_00039	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
MACFILCD_00040	5.51e-240	-	4.2.1.113	-	M	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Mandelate Racemase Muconate Lactonizing
MACFILCD_00041	2.15e-216	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
MACFILCD_00042	0.0	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	RNA cap guanine-N2 methyltransferase
MACFILCD_00043	0.0	-	-	-	-	-	-	-	-
MACFILCD_00044	4.7e-57	-	-	-	S	ko:K06960	-	ko00000	KH domain
MACFILCD_00045	6.71e-285	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
MACFILCD_00046	3.9e-213	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MACFILCD_00049	2.05e-173	-	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	FtsJ-like methyltransferase
MACFILCD_00051	7.48e-171	-	-	-	S	ko:K06911	-	ko00000	Pirin
MACFILCD_00052	0.0	-	-	-	M	-	-	-	AsmA-like C-terminal region
MACFILCD_00054	8.82e-203	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
MACFILCD_00055	0.0	-	2.7.1.51	-	G	ko:K00879	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MACFILCD_00057	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
MACFILCD_00058	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
MACFILCD_00059	2.34e-123	-	-	-	-	-	-	-	-
MACFILCD_00060	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	N-terminal domain of BNR-repeat neuraminidase
MACFILCD_00061	2.34e-134	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
MACFILCD_00062	7.29e-60	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
MACFILCD_00063	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
MACFILCD_00064	0.0	-	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	ThiC-associated domain
MACFILCD_00065	6.54e-222	ytpP	2.7.1.180, 5.3.4.1	-	CO	ko:K01829,ko:K03671,ko:K03734,ko:K06196	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko02000,ko03110	cell redox homeostasis
MACFILCD_00066	1.3e-139	-	-	-	K	-	-	-	ECF sigma factor
MACFILCD_00068	2.37e-222	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
MACFILCD_00070	2.77e-186	-	-	-	O	-	-	-	Parallel beta-helix repeats
MACFILCD_00071	0.0	-	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
MACFILCD_00072	2.4e-285	-	-	-	Q	-	-	-	Multicopper oxidase
MACFILCD_00073	3.07e-208	-	-	-	EG	-	-	-	EamA-like transporter family
MACFILCD_00074	2.57e-120	-	-	-	L	-	-	-	Protein of unknown function DUF262
MACFILCD_00076	1.48e-272	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MACFILCD_00077	6.48e-244	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
MACFILCD_00078	1.82e-229	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
MACFILCD_00079	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MACFILCD_00080	0.0	-	-	-	P	ko:K13895	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MACFILCD_00081	0.0	-	-	-	EP	ko:K13894	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MACFILCD_00082	8.08e-185	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
MACFILCD_00083	1.65e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
MACFILCD_00084	1.65e-221	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase PanE/ApbA C terminal
MACFILCD_00085	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate--tetrahydrofolate ligase
MACFILCD_00086	5.55e-143	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
MACFILCD_00087	1.67e-313	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
MACFILCD_00088	2.18e-117	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
MACFILCD_00089	5.53e-285	-	5.4.99.22	-	M	ko:K06178	-	ko00000,ko01000,ko03009	translation initiation factor activity
MACFILCD_00090	2.29e-136	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
MACFILCD_00091	7.4e-93	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
MACFILCD_00092	8.02e-130	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MACFILCD_00093	8.59e-293	-	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 57
MACFILCD_00094	5.2e-315	-	-	-	G	-	-	-	Glycosyl transferase 4-like domain
MACFILCD_00095	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 31
MACFILCD_00096	1.22e-249	-	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	chorismate binding enzyme
MACFILCD_00097	3.89e-313	-	-	-	C	ko:K00185	-	ko00000	Polysulphide reductase, NrfD
MACFILCD_00099	6.14e-155	-	-	-	C	-	-	-	Cytochrome c
MACFILCD_00100	1.5e-296	-	-	-	P	-	-	-	ABC-type Zn2 transport system, periplasmic component surface adhesin
MACFILCD_00101	0.0	-	-	-	C	-	-	-	Cytochrome c
MACFILCD_00103	9.72e-61	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MACFILCD_00104	4.59e-270	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
MACFILCD_00105	6.74e-307	-	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
MACFILCD_00106	1.05e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
MACFILCD_00107	1.23e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
MACFILCD_00108	0.0	-	-	-	J	-	-	-	Beta-Casp domain
MACFILCD_00109	2.24e-141	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MACFILCD_00110	1.02e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Queuosine biosynthesis protein QueC
MACFILCD_00111	1.78e-97	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	QueF-like protein
MACFILCD_00112	0.0	kefA	-	-	M	ko:K05802,ko:K22051	-	ko00000,ko02000	cellular water homeostasis
MACFILCD_00113	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MACFILCD_00114	7.46e-238	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MACFILCD_00115	1.18e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin resistance protein BacA
MACFILCD_00118	2.58e-85	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
MACFILCD_00119	6.59e-315	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MACFILCD_00120	1.65e-303	-	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
MACFILCD_00121	1.33e-52	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MACFILCD_00122	4.17e-260	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MACFILCD_00124	8.29e-100	cysJ	1.8.1.2	-	C	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	hydroxylamine reductase activity
MACFILCD_00126	5.74e-200	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
MACFILCD_00127	1.06e-169	BT0174	-	-	C	ko:K04488	-	ko00000	iron-sulfur transferase activity
MACFILCD_00128	2.08e-240	BT0173	-	-	S	-	-	-	Psort location Cytoplasmic, score
MACFILCD_00130	5.72e-271	-	2.1.1.72	-	H	ko:K07318	-	ko00000,ko01000,ko02048	PFAM D12 class N6 adenine-specific DNA methyltransferase
MACFILCD_00131	6.72e-210	-	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
MACFILCD_00136	1.48e-275	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
MACFILCD_00137	2.1e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MACFILCD_00138	1.75e-229	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
MACFILCD_00139	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
MACFILCD_00140	5.9e-233	-	2.7.7.13	-	JM	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
MACFILCD_00141	4.47e-176	-	-	-	S	-	-	-	Phosphodiester glycosidase
MACFILCD_00142	0.0	-	-	GT2	M	ko:K03820	-	ko00000,ko01000	Carbon-nitrogen hydrolase
MACFILCD_00143	4.64e-52	-	-	-	C	-	-	-	4Fe-4S single cluster domain of Ferredoxin I
MACFILCD_00144	4.58e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
MACFILCD_00145	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
MACFILCD_00146	6.92e-235	-	-	-	S	-	-	-	Acyltransferase family
MACFILCD_00147	1.07e-269	-	-	-	O	-	-	-	Cytochrome C assembly protein
MACFILCD_00148	3.24e-134	-	-	-	O	-	-	-	Cytochrome C assembly protein
MACFILCD_00149	1.74e-181	ccs1	-	-	O	ko:K07399	-	ko00000	cytochrome c biogenesis protein
MACFILCD_00150	4.88e-209	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion transport
MACFILCD_00151	4.31e-180	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MACFILCD_00152	4.99e-228	fatC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
MACFILCD_00153	2.65e-220	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
MACFILCD_00154	1.71e-264	-	-	-	J	-	-	-	Endoribonuclease L-PSP
MACFILCD_00155	0.0	-	-	-	C	-	-	-	Di-haem oxidoreductase, putative peroxidase
MACFILCD_00156	1.03e-243	-	-	-	S	-	-	-	Imelysin
MACFILCD_00157	1.59e-142	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
MACFILCD_00159	2.59e-125	-	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Phosphoribosyl transferase domain
MACFILCD_00160	0.0	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	Helix-hairpin-helix class 2 (Pol1 family) motifs
MACFILCD_00161	1.12e-248	-	-	-	M	-	-	-	HlyD family secretion protein
MACFILCD_00162	2.52e-102	MA20_05485	-	-	S	-	-	-	Putative bacterial sensory transduction regulator
MACFILCD_00163	0.0	-	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
MACFILCD_00164	6.21e-304	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MACFILCD_00165	0.0	-	-	-	D	-	-	-	Tetratricopeptide repeat
MACFILCD_00166	2.18e-195	-	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MACFILCD_00167	0.0	-	-	-	-	-	-	-	-
MACFILCD_00168	1.38e-223	-	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
MACFILCD_00169	6.68e-314	-	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
MACFILCD_00170	1.21e-153	-	4.1.3.38	-	E	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	branched-chain-amino-acid transaminase activity
MACFILCD_00171	7.63e-249	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MACFILCD_00172	2.09e-150	-	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
MACFILCD_00173	4.49e-269	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
MACFILCD_00175	2.5e-170	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
MACFILCD_00176	7.35e-119	-	-	-	T	ko:K07005	-	ko00000	pyridoxamine 5'-phosphate
MACFILCD_00177	1.51e-173	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Glutamine amidotransferase class-I
MACFILCD_00179	4.96e-113	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Cys-tRNA(Pro) hydrolase activity
MACFILCD_00180	0.0	mmyX	5.3.1.12	-	F	ko:K01812,ko:K07149,ko:K16139	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score
MACFILCD_00181	2.07e-95	-	-	-	-	-	-	-	-
MACFILCD_00182	2.36e-72	-	-	-	-	-	-	-	-
MACFILCD_00184	2.53e-146	-	-	-	Q	-	-	-	PA14
MACFILCD_00185	0.0	-	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	B12 binding domain
MACFILCD_00186	1.66e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
MACFILCD_00187	2.34e-108	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MACFILCD_00189	0.0	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
MACFILCD_00190	2.52e-281	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
MACFILCD_00192	1.12e-116	agmK	1.8.1.8	-	O	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	belongs to the thioredoxin family
MACFILCD_00193	3.86e-181	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
MACFILCD_00195	0.0	-	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
MACFILCD_00196	6.26e-218	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MACFILCD_00197	9.37e-256	-	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	endonuclease III
MACFILCD_00198	1.22e-143	aat	2.3.2.6	-	O	ko:K00684	-	ko00000,ko01000	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MACFILCD_00199	0.0	-	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Pyruvate phosphate dikinase, PEP/pyruvate binding domain
MACFILCD_00200	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglucose isomerase
MACFILCD_00201	9.49e-262	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
MACFILCD_00202	1.39e-221	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
MACFILCD_00204	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
MACFILCD_00205	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
MACFILCD_00206	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
MACFILCD_00207	2.94e-131	-	-	-	-	-	-	-	-
MACFILCD_00208	1.59e-243	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
MACFILCD_00211	8.93e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyrroline-5-carboxylate reductase dimerisation
MACFILCD_00212	8.1e-160	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
MACFILCD_00213	5.51e-211	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
MACFILCD_00214	6.59e-227	-	-	-	S	-	-	-	Protein conserved in bacteria
MACFILCD_00215	2.01e-34	-	-	-	KLT	-	-	-	Tyrosine-protein kinase, subgroup, catalytic domain
MACFILCD_00216	0.0	-	4.1.99.1	-	E	ko:K01667	ko00380,map00380	ko00000,ko00001,ko01000	Beta-eliminating lyase
MACFILCD_00217	1.66e-143	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
MACFILCD_00218	1.05e-256	-	-	-	S	-	-	-	Domain of unknown function (DUF4105)
MACFILCD_00219	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	B3/4 domain
MACFILCD_00220	6.99e-242	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Aminoacyl tRNA synthetase class II, N-terminal domain
MACFILCD_00221	1.92e-284	-	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
MACFILCD_00222	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
MACFILCD_00223	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Hsp90 protein
MACFILCD_00224	2.33e-172	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
MACFILCD_00226	2.32e-259	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MACFILCD_00227	1.51e-73	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MACFILCD_00228	7.45e-231	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	maintenance of DNA repeat elements
MACFILCD_00229	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	defense response to virus
MACFILCD_00230	1.37e-273	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MACFILCD_00231	9.25e-103	-	-	-	K	-	-	-	Transcriptional regulator
MACFILCD_00232	7.1e-311	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
MACFILCD_00233	2.64e-214	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
MACFILCD_00234	3.42e-135	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K00788,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MACFILCD_00235	2.33e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MACFILCD_00236	2.47e-116	gepA	-	-	K	-	-	-	Phage-associated protein
MACFILCD_00238	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
MACFILCD_00239	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
MACFILCD_00240	1.21e-241	-	-	-	E	ko:K07588	-	ko00000,ko01000	ArgK protein
MACFILCD_00241	2.21e-113	-	-	-	F	ko:K08311	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	NUDIX domain
MACFILCD_00242	0.0	sepA	-	-	Q	-	-	-	COG2015, Alkyl sulfatase and related hydrolases
MACFILCD_00243	2.83e-121	-	-	-	-	-	-	-	-
MACFILCD_00244	1.71e-110	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MACFILCD_00245	1.22e-290	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
MACFILCD_00246	8.17e-159	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MACFILCD_00247	1.53e-241	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase
MACFILCD_00249	1.69e-107	-	-	-	K	-	-	-	DNA-binding transcription factor activity
MACFILCD_00250	4.2e-264	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Biotin-lipoyl like
MACFILCD_00251	0.0	-	-	-	V	-	-	-	AcrB/AcrD/AcrF family
MACFILCD_00252	5.02e-115	-	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Dihydrofolate reductase
MACFILCD_00253	5.77e-208	-	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Thymidylate synthase
MACFILCD_00254	0.0	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phospholipase D. Active site motifs.
MACFILCD_00255	0.0	-	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	HMGL-like
MACFILCD_00257	0.0	-	-	-	V	ko:K03327	-	ko00000,ko02000	MatE
MACFILCD_00258	1.23e-255	-	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Iron-sulfur cluster assembly protein
MACFILCD_00259	6.78e-42	-	-	-	S	-	-	-	PurA ssDNA and RNA-binding protein
MACFILCD_00261	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	LeuA allosteric (dimerisation) domain
MACFILCD_00262	0.0	prlC	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
MACFILCD_00263	2.24e-282	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MACFILCD_00264	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MACFILCD_00265	0.0	-	-	-	MU	ko:K18139	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Outer membrane efflux protein
MACFILCD_00267	0.0	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
MACFILCD_00268	1.59e-150	-	-	-	-	-	-	-	-
MACFILCD_00271	2.17e-101	ptsN	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
MACFILCD_00272	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
MACFILCD_00273	7.09e-253	-	-	-	L	-	-	-	Transposase IS200 like
MACFILCD_00274	0.0	-	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
MACFILCD_00275	1.94e-268	-	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MACFILCD_00276	3.89e-149	dedA	-	-	S	-	-	-	FtsZ-dependent cytokinesis
MACFILCD_00277	2.62e-116	-	-	-	S	-	-	-	nitrogen fixation
MACFILCD_00278	2.09e-72	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MACFILCD_00279	1.72e-71	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MACFILCD_00280	6.23e-113	-	-	-	CO	-	-	-	cell redox homeostasis
MACFILCD_00282	7.41e-181	-	-	-	-	-	-	-	-
MACFILCD_00284	0.0	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
MACFILCD_00286	4.02e-144	-	-	-	-	-	-	-	-
MACFILCD_00287	1.71e-64	-	-	-	K	-	-	-	DNA-binding transcription factor activity
MACFILCD_00290	2.15e-34	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MACFILCD_00291	2.12e-141	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MACFILCD_00292	3.14e-65	-	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	Domain of unknown function DUF83
MACFILCD_00293	1.04e-130	-	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	DEAD-like helicases superfamily
MACFILCD_00294	1.04e-112	cas5d	-	-	S	ko:K19119	-	ko00000,ko02048	TIGRFAM CRISPR-associated protein Cas5
MACFILCD_00295	2.48e-135	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
MACFILCD_00296	3.57e-124	-	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
MACFILCD_00297	1.13e-285	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
MACFILCD_00298	0.0	-	1.2.1.88, 1.5.5.2	-	CE	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko03000	Proline dehydrogenase
MACFILCD_00300	1.01e-45	-	-	-	S	-	-	-	R3H domain
MACFILCD_00301	0.0	-	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Catalase
MACFILCD_00303	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
MACFILCD_00304	3.63e-135	rbr	-	-	C	-	-	-	Rubrerythrin
MACFILCD_00305	5.35e-145	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MACFILCD_00307	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk_gamma
MACFILCD_00308	5.68e-180	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	polysaccharide export
MACFILCD_00309	0.0	gumC	-	-	DM	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	PFAM lipopolysaccharide biosynthesis protein
MACFILCD_00310	1.11e-163	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	protein tyrosine phosphatase activity
MACFILCD_00311	2.3e-174	-	-	-	M	-	-	-	Bacterial sugar transferase
MACFILCD_00312	1.63e-187	wbyL	-	GT2	M	ko:K13002	-	ko00000,ko01000,ko01003,ko01005	transferase activity, transferring glycosyl groups
MACFILCD_00313	4.23e-292	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MACFILCD_00314	8.15e-285	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MACFILCD_00315	9.62e-292	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
MACFILCD_00316	2e-240	-	-	-	-	-	-	-	-
MACFILCD_00317	6.18e-262	-	-	-	M	ko:K02847,ko:K13009	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
MACFILCD_00318	6.19e-201	-	-	-	S	-	-	-	Glycosyl transferase family 11
MACFILCD_00319	3.24e-250	-	-	-	M	-	-	-	Glycosyl transferases group 1
MACFILCD_00320	6.11e-278	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
MACFILCD_00321	4.87e-281	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MACFILCD_00322	0.0	-	-	-	-	-	-	-	-
MACFILCD_00323	2.67e-113	-	-	-	S	ko:K03818	-	ko00000,ko01000	maltose O-acetyltransferase activity
MACFILCD_00324	1.42e-209	-	-	-	M	-	-	-	PFAM glycosyl transferase family 2
MACFILCD_00325	6.17e-237	-	-	-	M	-	-	-	Glycosyl transferase, family 2
MACFILCD_00326	1.55e-39	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
MACFILCD_00327	8.91e-123	-	-	-	C	-	-	-	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MACFILCD_00328	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
MACFILCD_00329	3.66e-229	-	-	-	C	-	-	-	Nitroreductase family
MACFILCD_00330	0.0	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
MACFILCD_00332	1.25e-283	-	-	-	S	-	-	-	very-long-chain-acyl-CoA dehydrogenase activity
MACFILCD_00333	2.93e-93	-	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
MACFILCD_00334	2.71e-303	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
MACFILCD_00335	0.0	-	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
MACFILCD_00336	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MACFILCD_00338	2.48e-315	-	1.1.1.40	-	C	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Malic enzyme, NAD binding domain
MACFILCD_00339	0.0	-	-	-	I	ko:K06889,ko:K09914	-	ko00000	PFAM Prenyltransferase squalene oxidase
MACFILCD_00340	9.81e-230	exsH	3.2.1.178, 3.2.1.18, 3.2.1.52	GH16,GH20,GH33	G	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	xyloglucan:xyloglucosyl transferase activity
MACFILCD_00341	2.6e-259	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
MACFILCD_00342	9.25e-128	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MACFILCD_00343	3.72e-158	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
MACFILCD_00344	0.0	yidC	-	-	O	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	serine-type endopeptidase activity
MACFILCD_00345	4.38e-266	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
MACFILCD_00347	1.43e-309	-	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Seryl-tRNA synthetase N-terminal domain
MACFILCD_00348	2.36e-273	-	-	-	E	-	-	-	Alcohol dehydrogenase GroES-like domain
MACFILCD_00350	3.49e-216	-	3.5.1.53	-	K	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
MACFILCD_00351	3.82e-231	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
MACFILCD_00352	5.34e-214	-	-	-	S	-	-	-	Protein of unknown function DUF58
MACFILCD_00353	2.63e-135	-	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	Peptidyl-tRNA hydrolase
MACFILCD_00354	0.0	-	-	-	M	-	-	-	Transglycosylase
MACFILCD_00355	0.0	-	3.4.24.3	-	NU	ko:K01387	-	ko00000,ko01000,ko01002,ko02042	translation initiation factor activity
MACFILCD_00356	0.0	-	-	-	H	-	-	-	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MACFILCD_00357	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MACFILCD_00359	0.0	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
MACFILCD_00360	2.95e-299	-	1.12.99.6	-	C	ko:K06282	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	NiFe/NiFeSe hydrogenase small subunit C-terminal
MACFILCD_00361	0.0	-	1.12.99.6	-	C	ko:K06281	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nickel-dependent hydrogenase
MACFILCD_00362	6.49e-290	hyaC	-	-	C	ko:K03620	ko02020,map02020	ko00000,ko00001	Prokaryotic cytochrome b561
MACFILCD_00363	3.4e-126	-	-	-	C	ko:K03605	-	ko00000,ko01000,ko01002	Hydrogenase maturation protease
MACFILCD_00364	2.09e-76	-	-	-	C	ko:K04651	-	ko00000,ko03110	Hydrogenase/urease nickel incorporation, metallochaperone, hypA
MACFILCD_00366	6.77e-87	-	-	-	S	ko:K09940	-	ko00000	Domain of unknown function (DUF4870)
MACFILCD_00367	1.24e-179	-	-	-	M	-	-	-	NLP P60 protein
MACFILCD_00368	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, domain 2
MACFILCD_00369	8.43e-155	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
MACFILCD_00370	5.93e-261	-	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MACFILCD_00374	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MACFILCD_00375	1.49e-250	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
MACFILCD_00376	1.09e-135	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
MACFILCD_00377	3.4e-173	-	-	-	S	-	-	-	peptidoglycan biosynthetic process
MACFILCD_00378	1.3e-206	-	1.4.1.16	-	S	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
MACFILCD_00380	0.000103	-	-	-	S	-	-	-	Entericidin EcnA/B family
MACFILCD_00381	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MACFILCD_00382	9.06e-135	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	5,10-methylenetetrahydrofolate reductase
MACFILCD_00383	7.12e-152	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MACFILCD_00384	7.99e-78	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MACFILCD_00385	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
MACFILCD_00386	1.5e-296	lpxK	2.7.1.130	-	M	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
MACFILCD_00387	4.56e-139	-	-	-	S	ko:K07164	-	ko00000	C4-type zinc ribbon domain
MACFILCD_00388	3.18e-264	-	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
MACFILCD_00389	3.68e-75	-	-	-	-	-	-	-	-
MACFILCD_00390	4.15e-191	-	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	MazG nucleotide pyrophosphohydrolase domain
MACFILCD_00391	2.92e-70	-	-	-	-	-	-	-	-
MACFILCD_00392	3.42e-180	-	-	-	S	-	-	-	competence protein
MACFILCD_00393	1.67e-100	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
MACFILCD_00397	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Sulfatase
MACFILCD_00398	1.3e-143	-	-	-	-	-	-	-	-
MACFILCD_00399	9.08e-165	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
MACFILCD_00400	4.82e-178	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MACFILCD_00401	2.71e-300	-	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	16S rRNA methyltransferase RsmB/F
MACFILCD_00402	9.39e-117	-	3.1.6.8	-	P	ko:K01134	ko00600,ko04142,map00600,map04142	ko00000,ko00001,ko01000	COG3119 Arylsulfatase A
MACFILCD_00403	2.9e-316	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Arginosuccinate synthase
MACFILCD_00405	2.79e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MACFILCD_00406	8.43e-59	-	-	-	S	-	-	-	Zinc ribbon domain
MACFILCD_00407	4.77e-310	-	-	-	S	-	-	-	PFAM CBS domain containing protein
MACFILCD_00408	2.06e-150	-	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
MACFILCD_00409	2.8e-81	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
MACFILCD_00411	2.27e-175	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
MACFILCD_00412	1.62e-227	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
MACFILCD_00413	2.14e-148	-	-	-	S	-	-	-	3D domain
MACFILCD_00414	2.15e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MACFILCD_00415	9.91e-171	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
MACFILCD_00416	3.19e-111	aglS	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
MACFILCD_00417	5.28e-100	exbD2	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
MACFILCD_00418	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
MACFILCD_00419	1.28e-193	-	-	-	-	-	-	-	-
MACFILCD_00420	7.71e-278	-	-	-	K	-	-	-	sequence-specific DNA binding
MACFILCD_00421	0.0	-	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	Ribonuclease E/G family
MACFILCD_00422	5.06e-236	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Actin
MACFILCD_00423	0.0	lacZ_17	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
MACFILCD_00425	2.24e-263	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
MACFILCD_00427	1.3e-177	-	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
MACFILCD_00428	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
MACFILCD_00429	5.55e-116	-	-	-	-	-	-	-	-
MACFILCD_00430	1.89e-166	-	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	SAICAR synthetase
MACFILCD_00431	0.0	-	-	-	K	-	-	-	Transcription elongation factor, N-terminal
MACFILCD_00432	0.0	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MACFILCD_00433	1.71e-179	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MACFILCD_00434	1.73e-307	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MACFILCD_00435	1.34e-201	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase, N-terminal
MACFILCD_00436	1.06e-109	-	-	-	S	ko:K15977	-	ko00000	DoxX
MACFILCD_00437	1.31e-290	-	4.2.1.129, 5.4.99.17	-	I	ko:K06045	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
MACFILCD_00438	4.7e-193	-	-	-	-	-	-	-	-
MACFILCD_00439	6.8e-224	-	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
MACFILCD_00440	9.39e-183	-	-	-	H	-	-	-	ThiF family
MACFILCD_00441	8.92e-111	-	-	-	U	-	-	-	response to pH
MACFILCD_00442	1.74e-224	-	-	-	-	-	-	-	-
MACFILCD_00443	4.09e-218	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MACFILCD_00445	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
MACFILCD_00446	2.55e-270	-	-	-	S	-	-	-	COGs COG4299 conserved
MACFILCD_00447	5.1e-153	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
MACFILCD_00448	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein dimerisation domain
MACFILCD_00449	0.0	-	-	-	-	-	-	-	-
MACFILCD_00450	6.27e-219	-	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	ATP synthase A chain
MACFILCD_00451	1.65e-11	-	-	-	S	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	PFAM H transporting two-sector ATPase C subunit
MACFILCD_00452	4.38e-78	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase B/B' CF(0)
MACFILCD_00453	1.59e-86	-	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase delta (OSCP) subunit
MACFILCD_00454	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MACFILCD_00455	4.5e-201	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MACFILCD_00456	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MACFILCD_00457	5.04e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MACFILCD_00458	1.38e-139	-	-	-	-	-	-	-	-
MACFILCD_00459	8.17e-124	sprT	-	-	K	-	-	-	SprT-like family
MACFILCD_00460	4.27e-275	-	-	-	S	-	-	-	COGs COG4299 conserved
MACFILCD_00461	5.18e-283	-	2.6.1.59	-	M	ko:K02805	-	ko00000,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
MACFILCD_00462	2.98e-115	flmH	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MACFILCD_00463	1.95e-222	-	-	-	M	-	-	-	Glycosyl transferase family 2
MACFILCD_00464	1.08e-73	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
MACFILCD_00465	1.93e-77	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
MACFILCD_00468	0.0	-	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
MACFILCD_00469	1.77e-234	-	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Biotin and Thiamin Synthesis associated domain
MACFILCD_00470	0.0	-	-	-	P	-	-	-	Sulfatase
MACFILCD_00471	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
MACFILCD_00472	2.04e-293	-	-	-	O	ko:K09015	-	ko00000	Uncharacterized protein family (UPF0051)
MACFILCD_00473	0.0	-	-	-	O	ko:K09014	-	ko00000	Uncharacterized protein family (UPF0051)
MACFILCD_00474	1.02e-178	-	-	-	O	ko:K09013	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
MACFILCD_00475	6.78e-100	-	-	-	P	ko:K09825	-	ko00000,ko03000	Ferric uptake regulator family
MACFILCD_00476	2.14e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
MACFILCD_00477	1.93e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal prokaryotic L21 protein
MACFILCD_00478	3.34e-106	-	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
MACFILCD_00479	3.73e-200	-	-	-	S	ko:K06889	-	ko00000	alpha beta
MACFILCD_00481	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
MACFILCD_00482	0.0	-	-	-	-	-	-	-	-
MACFILCD_00483	2.58e-225	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
MACFILCD_00485	1.36e-175	-	-	-	-	-	-	-	-
MACFILCD_00486	3.35e-131	-	-	-	L	-	-	-	Conserved hypothetical protein 95
MACFILCD_00487	1.18e-309	-	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
MACFILCD_00488	1.98e-232	-	-	-	S	-	-	-	Aspartyl protease
MACFILCD_00489	3.37e-272	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MACFILCD_00490	2.4e-160	-	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	DNA / pantothenate metabolism flavoprotein
MACFILCD_00491	3.38e-279	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
MACFILCD_00492	1.94e-104	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
MACFILCD_00493	2.48e-173	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
MACFILCD_00494	0.0	-	-	-	L	-	-	-	Polyphosphate kinase 2 (PPK2)
MACFILCD_00495	0.0	-	-	-	S	-	-	-	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
MACFILCD_00496	2.31e-259	-	-	-	M	-	-	-	Peptidase family M23
MACFILCD_00498	8.37e-126	-	4.1.1.36	-	H	ko:K01598	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Flavoprotein
MACFILCD_00499	1.31e-81	-	-	-	DJ	-	-	-	Addiction module toxin, RelE StbE family
MACFILCD_00500	2.34e-208	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
MACFILCD_00502	1.26e-139	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
MACFILCD_00503	0.0	-	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MACFILCD_00504	4.07e-246	-	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR synthase related protein, N-terminal domain
MACFILCD_00505	1.84e-105	-	-	-	S	ko:K15977	-	ko00000	DoxX
MACFILCD_00506	1.72e-243	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
MACFILCD_00507	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
MACFILCD_00508	1.84e-177	-	-	-	-	-	-	-	-
MACFILCD_00509	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DbpA RNA binding domain
MACFILCD_00510	0.0	-	-	-	P	ko:K01138	-	ko00000,ko01000	PA14 domain
MACFILCD_00511	6.93e-147	-	-	-	L	-	-	-	Membrane
MACFILCD_00513	0.0	gcvP	1.4.4.2	-	E	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MACFILCD_00514	6.67e-86	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MACFILCD_00515	7e-268	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Aminomethyltransferase folate-binding domain
MACFILCD_00516	1.11e-261	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MACFILCD_00517	4.07e-217	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MACFILCD_00518	4.22e-267	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
MACFILCD_00519	2.45e-268	-	-	-	M	-	-	-	Glycosyl transferase 4-like
MACFILCD_00520	2.39e-224	-	-	-	M	ko:K07276	-	ko00000	Mitochondrial fission ELM1
MACFILCD_00521	3.9e-270	-	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
MACFILCD_00522	1.11e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MACFILCD_00523	2.11e-121	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MACFILCD_00524	1.46e-140	-	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S4/S9 N-terminal domain
MACFILCD_00525	5.71e-191	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
MACFILCD_00529	1.07e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MACFILCD_00530	0.0	-	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
MACFILCD_00531	5.92e-289	-	3.5.1.42	-	S	ko:K03742	ko00760,map00760	ko00000,ko00001,ko01000	Competence-damaged protein
MACFILCD_00532	6.87e-153	-	-	-	O	-	-	-	methyltransferase activity
MACFILCD_00533	3.22e-182	-	-	-	U	ko:K20276	ko02024,map02024	ko00000,ko00001	domain, Protein
MACFILCD_00534	0.0	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
MACFILCD_00535	8.76e-261	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Elongator protein 3, MiaB family, Radical SAM
MACFILCD_00536	1.1e-197	-	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SRP54-type protein, GTPase domain
MACFILCD_00537	9.48e-205	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MACFILCD_00538	4.95e-103	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MACFILCD_00539	4.76e-288	-	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase II
MACFILCD_00540	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), anti-codon binding domain
MACFILCD_00541	0.0	-	-	-	-	-	-	-	-
MACFILCD_00542	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
MACFILCD_00543	3.99e-258	-	-	-	S	-	-	-	ankyrin repeats
MACFILCD_00544	1.05e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
MACFILCD_00545	1.06e-44	-	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S21
MACFILCD_00546	0.0	-	2.7.1.167, 2.7.7.70	-	M	ko:K03272	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	pfkB family carbohydrate kinase
MACFILCD_00547	8.25e-131	-	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
MACFILCD_00548	1.03e-116	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Polynucleotide kinase 3 phosphatase
MACFILCD_00549	1.26e-222	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
MACFILCD_00551	6.06e-251	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
MACFILCD_00552	1.63e-189	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MACFILCD_00553	1.4e-195	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MACFILCD_00554	2.31e-187	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MACFILCD_00555	1.48e-120	-	-	-	M	ko:K06142	-	ko00000	Outer membrane protein (OmpH-like)
MACFILCD_00556	3.42e-196	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MACFILCD_00557	6.38e-151	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MACFILCD_00558	4.78e-63	-	-	-	-	-	-	-	-
MACFILCD_00559	1.19e-57	-	-	-	-	-	-	-	-
MACFILCD_00560	8.41e-202	-	-	-	S	-	-	-	DisA bacterial checkpoint controller nucleotide-binding
MACFILCD_00562	1.7e-153	-	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	AAA domain
MACFILCD_00563	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
MACFILCD_00564	0.0	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
MACFILCD_00565	9.93e-180	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MACFILCD_00567	1.33e-174	-	-	-	NU	-	-	-	Prepilin-type N-terminal cleavage methylation domain
MACFILCD_00569	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	PFAM coagulation factor 5 8 type domain protein
MACFILCD_00570	9.86e-168	-	-	-	M	-	-	-	Peptidase family M23
MACFILCD_00571	1.04e-144	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MACFILCD_00572	7.54e-201	-	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MACFILCD_00575	0.0	-	-	-	S	-	-	-	Terminase
MACFILCD_00576	2.36e-213	-	-	-	D	ko:K19234,ko:K19236	ko01503,map01503	ko00000,ko00001,ko01002,ko01011	ErfK ybiS ycfS ynhG family protein
MACFILCD_00577	8.11e-152	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MACFILCD_00578	3.01e-49	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal_S15
MACFILCD_00579	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MACFILCD_00580	9.05e-313	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	PFAM CBS domain containing protein
MACFILCD_00581	1.38e-310	-	-	-	S	-	-	-	PFAM CBS domain containing protein
MACFILCD_00582	0.0	-	-	-	C	-	-	-	Cytochrome c554 and c-prime
MACFILCD_00583	1.63e-164	-	-	-	CO	-	-	-	Thioredoxin-like
MACFILCD_00584	1.1e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MACFILCD_00585	4.7e-156	-	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase
MACFILCD_00586	4.25e-238	pyrD	1.3.5.2	-	F	ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
MACFILCD_00587	0.0	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase alpha chain like domain
MACFILCD_00588	1.74e-140	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MACFILCD_00589	0.0	-	4.1.1.15	-	E	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase conserved domain
MACFILCD_00590	0.0	-	-	-	-	-	-	-	-
MACFILCD_00592	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
MACFILCD_00594	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
MACFILCD_00595	0.0	-	-	-	KT	ko:K02584	ko02020,map02020	ko00000,ko00001,ko03000	Bacterial regulatory protein, Fis family
MACFILCD_00596	9.28e-219	-	2.5.1.21	-	I	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01006	Squalene/phytoene synthase
MACFILCD_00597	0.0	-	-	-	S	-	-	-	Fungal chitosanase of glycosyl hydrolase group 75
MACFILCD_00598	9e-192	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
MACFILCD_00599	8.38e-98	-	-	-	-	-	-	-	-
MACFILCD_00600	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
MACFILCD_00603	9.85e-147	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
MACFILCD_00607	1.07e-301	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	efflux transmembrane transporter activity
MACFILCD_00610	4.36e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Enoyl-CoA hydratase/isomerase
MACFILCD_00611	2.6e-257	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
MACFILCD_00613	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MACFILCD_00614	4.69e-79	rsfS	-	-	S	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MACFILCD_00616	8.78e-16	-	-	-	-	-	-	-	-
MACFILCD_00622	4.24e-21	-	-	-	U	-	-	-	Protein of unknown function DUF262
MACFILCD_00624	3.76e-08	-	-	-	S	-	-	-	Ankyrin repeats (many copies)
MACFILCD_00627	6.45e-57	ntrX	-	-	T	ko:K13599	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM sigma-54 factor interaction domain-containing protein
MACFILCD_00628	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MACFILCD_00629	7.58e-140	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease
MACFILCD_00630	3.47e-119	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MACFILCD_00631	0.0	-	-	-	CO	-	-	-	Disulphide bond corrector protein DsbC
MACFILCD_00632	1.86e-94	-	-	-	O	-	-	-	OsmC-like protein
MACFILCD_00634	3.42e-111	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
MACFILCD_00635	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
MACFILCD_00637	1.46e-204	-	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
MACFILCD_00638	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
MACFILCD_00639	4.97e-168	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MACFILCD_00640	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MACFILCD_00643	6.2e-155	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
MACFILCD_00644	1.24e-230	-	-	-	EP	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
MACFILCD_00645	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
MACFILCD_00646	9.67e-251	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
MACFILCD_00647	2.31e-127	-	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Recombination protein O N terminal
MACFILCD_00648	1.14e-182	-	-	-	S	-	-	-	Tetratricopeptide repeat
MACFILCD_00649	0.0	dxs	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MACFILCD_00650	3.08e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
MACFILCD_00651	0.0	-	-	-	O	-	-	-	C-terminal four TMM region of protein-O-mannosyltransferase
MACFILCD_00652	0.0	-	-	-	T	-	-	-	Bacterial regulatory protein, Fis family
MACFILCD_00653	7.39e-274	-	-	-	T	-	-	-	PAS domain
MACFILCD_00654	3.37e-97	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase superfamily
MACFILCD_00655	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	BPG-independent PGAM N-terminus (iPGM_N)
MACFILCD_00656	4.16e-85	-	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S12/S23
MACFILCD_00657	2.91e-104	-	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S7p/S5e
MACFILCD_00658	0.0	-	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MACFILCD_00659	3.67e-65	-	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S10p/S20e
MACFILCD_00660	3.86e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MACFILCD_00661	9.43e-132	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L4/L1 family
MACFILCD_00662	8.72e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MACFILCD_00663	1.85e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MACFILCD_00664	1.05e-58	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MACFILCD_00665	4.05e-152	-	-	-	-	-	-	-	-
MACFILCD_00666	4.97e-70	-	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
MACFILCD_00667	5.2e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MACFILCD_00668	3.42e-97	-	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MACFILCD_00669	2.36e-34	-	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L29 protein
MACFILCD_00670	2.19e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MACFILCD_00671	6.79e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MACFILCD_00673	6.2e-203	-	-	-	-	-	-	-	-
MACFILCD_00674	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MACFILCD_00675	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
MACFILCD_00676	3.33e-254	-	5.2.1.8	-	O	ko:K03771	-	ko00000,ko01000,ko03110	SurA N-terminal domain
MACFILCD_00677	9.04e-172	-	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MACFILCD_00678	1.43e-142	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
MACFILCD_00684	1.9e-62	-	-	-	L	-	-	-	bacterial (prokaryotic) histone like domain
MACFILCD_00685	1.91e-204	-	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
MACFILCD_00686	2e-125	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
MACFILCD_00687	3.55e-173	-	-	-	F	-	-	-	NUDIX domain
MACFILCD_00688	1.22e-150	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Putative methyltransferase
MACFILCD_00689	1.39e-282	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MACFILCD_00690	5.64e-66	-	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
MACFILCD_00691	1.26e-183	-	-	-	DTZ	-	-	-	EF-hand, calcium binding motif
MACFILCD_00692	1.31e-214	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
MACFILCD_00693	5.39e-13	-	-	-	E	-	-	-	LysE type translocator
MACFILCD_00695	9.56e-51	-	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S16
MACFILCD_00696	4.45e-128	aroK	2.7.1.71	-	E	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MACFILCD_00697	3.6e-243	-	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MACFILCD_00698	1.16e-78	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
MACFILCD_00699	4.98e-117	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MACFILCD_00700	2.73e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MACFILCD_00701	1.22e-246	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MACFILCD_00702	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
MACFILCD_00703	2.36e-116	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MACFILCD_00708	0.0	-	-	-	CO	-	-	-	Thioredoxin-like
MACFILCD_00709	0.0	-	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	C-terminal, D2-small domain, of ClpB protein
MACFILCD_00711	1.34e-232	-	-	-	K	-	-	-	DNA-binding transcription factor activity
MACFILCD_00712	1.76e-79	-	-	-	S	-	-	-	PFAM Cupin 2 conserved barrel domain protein
MACFILCD_00713	6.76e-131	-	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MACFILCD_00714	0.0	-	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MACFILCD_00715	0.0	-	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MACFILCD_00717	2.4e-167	-	-	-	T	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MACFILCD_00718	0.0	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
MACFILCD_00720	2.66e-06	-	-	-	-	-	-	-	-
MACFILCD_00721	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
MACFILCD_00722	1.03e-265	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2219)
MACFILCD_00723	4.37e-203	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
MACFILCD_00724	2.63e-84	-	-	-	M	-	-	-	Lysin motif
MACFILCD_00725	4.33e-180	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
MACFILCD_00726	0.0	-	-	-	V	-	-	-	MatE
MACFILCD_00727	3.01e-252	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
MACFILCD_00729	1.45e-258	-	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MACFILCD_00731	4.01e-157	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
MACFILCD_00732	6.45e-266	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	RibD C-terminal domain
MACFILCD_00733	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MACFILCD_00734	4.27e-273	-	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
MACFILCD_00735	0.0	-	-	-	O	-	-	-	Trypsin
MACFILCD_00736	7.97e-108	-	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
MACFILCD_00737	0.0	-	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Oligonucleotide/oligosaccharide-binding (OB)-fold
MACFILCD_00738	3.52e-161	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
MACFILCD_00739	0.0	-	-	-	P	-	-	-	Cation transport protein
MACFILCD_00740	2.58e-178	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MACFILCD_00741	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
MACFILCD_00742	3.2e-70	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MACFILCD_00743	1.32e-101	manC	-	-	S	-	-	-	Cupin domain
MACFILCD_00744	0.0	-	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MACFILCD_00745	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
MACFILCD_00746	2.5e-188	pppL	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	protein serine/threonine phosphatase activity
MACFILCD_00747	4.34e-152	-	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Glycerol-3-phosphate acyltransferase
MACFILCD_00748	8.08e-236	gpsA	1.1.1.94	-	C	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MACFILCD_00749	8.62e-102	-	-	-	-	-	-	-	-
MACFILCD_00751	6.95e-264	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
MACFILCD_00752	1.32e-313	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
MACFILCD_00753	0.0	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
MACFILCD_00754	8.42e-05	-	-	-	-	-	-	-	-
MACFILCD_00755	0.0	-	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
MACFILCD_00756	2.44e-210	-	-	-	S	-	-	-	Rhomboid family
MACFILCD_00757	1.03e-266	-	-	-	E	-	-	-	FAD dependent oxidoreductase
MACFILCD_00758	2.64e-267	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MACFILCD_00761	0.0	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase
MACFILCD_00762	2e-120	-	-	-	K	-	-	-	ParB domain protein nuclease
MACFILCD_00765	2.63e-115	-	-	-	L	-	-	-	Staphylococcal nuclease homologues
MACFILCD_00766	7.66e-245	-	-	-	M	-	-	-	Alginate lyase
MACFILCD_00770	7.17e-104	yciA	-	-	I	ko:K10806	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	acyl-coa hydrolase
MACFILCD_00771	2.84e-315	hsrA	-	-	EGP	-	-	-	Major facilitator Superfamily
MACFILCD_00772	1.41e-289	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
MACFILCD_00773	2.07e-243	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MACFILCD_00774	2.62e-180	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MACFILCD_00775	0.0	-	3.2.1.23	-	G	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
MACFILCD_00776	1.25e-157	-	-	-	C	-	-	-	Nitroreductase family
MACFILCD_00777	0.0	-	-	-	E	-	-	-	Transglutaminase-like
MACFILCD_00778	5.58e-110	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
MACFILCD_00779	6.56e-112	-	-	-	S	ko:K08999	-	ko00000	Bifunctional nuclease
MACFILCD_00781	0.0	-	-	-	P	-	-	-	Citrate transporter
MACFILCD_00784	1.01e-255	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
MACFILCD_00785	0.0	-	-	-	I	-	-	-	Acyltransferase family
MACFILCD_00786	1.22e-251	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
MACFILCD_00787	1.61e-306	-	-	-	M	-	-	-	Glycosyl transferases group 1
MACFILCD_00788	4.21e-204	-	-	-	-	-	-	-	-
MACFILCD_00789	2.25e-287	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MACFILCD_00790	1.31e-244	-	5.1.3.20	-	M	ko:K03274	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-beta hydroxysteroid dehydrogenase/isomerase family
MACFILCD_00791	4.5e-234	-	-	GT9	M	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	ADP-heptose-lipopolysaccharide heptosyltransferase activity
MACFILCD_00792	7.08e-251	-	-	-	S	-	-	-	Glycosyltransferase like family 2
MACFILCD_00793	4.53e-244	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
MACFILCD_00794	4.39e-209	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
MACFILCD_00796	4.03e-239	-	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
MACFILCD_00797	9.36e-171	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MACFILCD_00798	1.17e-218	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
MACFILCD_00799	9e-65	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MACFILCD_00800	1.15e-86	-	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
MACFILCD_00801	1.15e-151	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
MACFILCD_00802	1.19e-256	-	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MACFILCD_00803	2.61e-128	-	-	-	-	-	-	-	-
MACFILCD_00804	5.05e-233	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MACFILCD_00805	2.58e-63	-	-	-	S	-	-	-	OST-HTH/LOTUS domain
MACFILCD_00806	7.51e-152	ppaX_1	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
MACFILCD_00807	1.58e-138	-	-	-	S	-	-	-	Maltose acetyltransferase
MACFILCD_00808	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	GMP synthase C terminal domain
MACFILCD_00809	0.0	-	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase / GMP reductase domain
MACFILCD_00810	1.43e-120	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
MACFILCD_00811	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
MACFILCD_00812	1.11e-113	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
MACFILCD_00814	2.89e-14	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
MACFILCD_00815	1.22e-27	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
MACFILCD_00817	3.73e-269	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
MACFILCD_00818	7.7e-255	-	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MACFILCD_00819	2.84e-286	-	-	-	S	-	-	-	Phosphotransferase enzyme family
MACFILCD_00820	3.23e-253	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MACFILCD_00822	3.34e-139	-	-	-	T	-	-	-	histone H2A K63-linked ubiquitination
MACFILCD_00823	1.14e-129	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MACFILCD_00824	5.11e-222	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
MACFILCD_00825	8.55e-214	-	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MACFILCD_00826	0.0	-	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
MACFILCD_00827	1.32e-235	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
MACFILCD_00828	1.38e-313	-	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
MACFILCD_00829	6.62e-257	-	-	-	S	ko:K11744	-	ko00000	AI-2E family transporter
MACFILCD_00830	5.68e-156	gph	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
MACFILCD_00831	6.6e-294	-	-	-	E	-	-	-	Amino acid permease
MACFILCD_00832	2.02e-173	-	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiG
MACFILCD_00834	1.79e-201	-	-	-	S	-	-	-	SigmaW regulon antibacterial
MACFILCD_00835	7.86e-242	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MACFILCD_00837	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
MACFILCD_00838	0.0	-	-	-	P	-	-	-	Dimerisation domain of Zinc Transporter
MACFILCD_00839	5.84e-173	-	-	-	K	-	-	-	Transcriptional regulator
MACFILCD_00840	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MACFILCD_00841	4.88e-169	-	4.3.99.3	-	O	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MACFILCD_00842	6.62e-182	-	2.7.13.3	-	Q	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Transposase
MACFILCD_00843	0.0	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MACFILCD_00844	2.2e-313	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
MACFILCD_00845	2.44e-238	-	-	-	E	-	-	-	Aminotransferase class-V
MACFILCD_00846	5.45e-234	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MACFILCD_00847	1.82e-214	-	-	-	K	-	-	-	LysR substrate binding domain
MACFILCD_00850	5.69e-287	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MACFILCD_00851	2.98e-295	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MACFILCD_00852	0.0	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
MACFILCD_00853	1.7e-301	-	4.2.1.129, 5.4.99.17, 5.5.1.16	-	I	ko:K06045,ko:K17811	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
MACFILCD_00854	4.58e-256	-	-	-	M	ko:K02022	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MACFILCD_00855	1.1e-160	-	-	-	S	-	-	-	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MACFILCD_00857	5.12e-71	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
MACFILCD_00858	7.81e-316	-	-	-	-	-	-	-	-
MACFILCD_00859	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
MACFILCD_00861	0.0	-	-	-	T	-	-	-	pathogenesis
MACFILCD_00862	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MACFILCD_00863	1.31e-114	ywrF	-	-	S	-	-	-	FMN binding
MACFILCD_00864	2.27e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MACFILCD_00865	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
MACFILCD_00866	7.64e-307	-	-	-	M	-	-	-	OmpA family
MACFILCD_00867	0.0	-	6.3.2.45	-	M	ko:K02558	-	ko00000,ko01000	Mur ligase family, catalytic domain
MACFILCD_00868	5.39e-220	-	-	-	E	-	-	-	Phosphoserine phosphatase
MACFILCD_00869	6.31e-171	-	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MACFILCD_00872	6.68e-198	-	2.5.1.55	-	M	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	DAHP synthetase I family
MACFILCD_00873	2.59e-170	cbiX	4.99.1.3	-	S	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	sirohydrochlorin cobaltochelatase activity
MACFILCD_00874	5.88e-163	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S2
MACFILCD_00875	2.05e-198	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MACFILCD_00876	2.65e-174	-	-	-	E	-	-	-	ATPases associated with a variety of cellular activities
MACFILCD_00878	2.93e-280	-	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate synthase
MACFILCD_00879	0.0	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
MACFILCD_00880	0.0	-	-	-	O	-	-	-	Trypsin
MACFILCD_00881	4.99e-274	-	-	-	-	-	-	-	-
MACFILCD_00882	1.53e-146	-	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
MACFILCD_00883	0.0	-	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase family (aconitate hydratase)
MACFILCD_00884	7.14e-141	-	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
MACFILCD_00885	1.11e-237	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
MACFILCD_00886	1.15e-238	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MACFILCD_00887	1.8e-216	-	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	POTRA domain, FtsQ-type
MACFILCD_00888	6.85e-227	ddl	6.3.2.4	-	M	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	D-ala D-ala ligase N-terminus
MACFILCD_00889	0.0	murB	-	-	M	-	-	-	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
MACFILCD_00890	4.56e-266	-	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MACFILCD_00891	1.33e-277	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Cell cycle protein
MACFILCD_00892	9.57e-159	mltD	-	CBM50	M	ko:K08307,ko:K12204,ko:K19224	-	ko00000,ko01000,ko01002,ko01011,ko02044	LysM domain
MACFILCD_00893	1.79e-312	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MACFILCD_00894	1.99e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MACFILCD_00895	0.0	-	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Mur ligase middle domain
MACFILCD_00896	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MACFILCD_00897	0.0	-	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein dimerisation domain
MACFILCD_00899	0.0	rsmH	2.1.1.199	-	M	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MACFILCD_00900	4.54e-105	-	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MACFILCD_00901	5.27e-189	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MACFILCD_00902	2.82e-154	-	-	-	S	-	-	-	UPF0126 domain
MACFILCD_00905	0.0	-	-	-	L	-	-	-	C-5 cytosine-specific DNA methylase
MACFILCD_00906	4.42e-235	-	-	-	V	-	-	-	HNH endonuclease
MACFILCD_00907	8.58e-45	-	-	-	-	-	-	-	-
MACFILCD_00909	3.28e-63	-	-	-	O	-	-	-	Torsin
MACFILCD_00910	1.87e-270	-	-	-	-	-	-	-	-
MACFILCD_00911	1.67e-46	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MACFILCD_00912	1.63e-43	-	-	-	-	-	-	-	-
MACFILCD_00913	4.5e-61	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
MACFILCD_00914	2.59e-313	-	-	-	D	-	-	-	MobA MobL family protein
MACFILCD_00915	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
MACFILCD_00916	1.89e-35	-	-	-	-	-	-	-	-
MACFILCD_00917	0.0	-	-	-	L	-	-	-	Domain of unknown function (DUF4368)
MACFILCD_00918	1.67e-08	-	-	-	S	-	-	-	Mac 1
MACFILCD_00919	2.41e-315	mnmE	-	-	J	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MACFILCD_00920	1.11e-262	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MACFILCD_00921	9.9e-202	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MACFILCD_00922	6.92e-183	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
MACFILCD_00923	7.52e-56	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
MACFILCD_00924	4.6e-180	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
MACFILCD_00925	4.35e-143	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
MACFILCD_00926	5.71e-284	-	-	-	M	-	-	-	Glycosyl transferases group 1
MACFILCD_00927	3.32e-288	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MACFILCD_00928	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
MACFILCD_00930	2.11e-154	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
MACFILCD_00931	8.4e-39	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
MACFILCD_00932	9.28e-249	-	-	-	M	-	-	-	Glycosyl transferase, family 2
MACFILCD_00934	1.1e-256	MA20_42350	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyl transferase, family 2
MACFILCD_00935	4.5e-283	-	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MACFILCD_00936	9.5e-239	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MACFILCD_00937	4.39e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MACFILCD_00940	5.49e-110	-	-	-	L	-	-	-	AAA ATPase domain
MACFILCD_00941	9.75e-58	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
MACFILCD_00946	1.57e-08	-	-	-	S	ko:K06867	-	ko00000	Ankyrin repeat protein
MACFILCD_00949	1.42e-42	pkn3	2.7.11.1	-	KLT	ko:K08282	-	ko00000,ko01000	Tyrosine-protein kinase, subgroup, catalytic domain
MACFILCD_00951	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
MACFILCD_00952	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR/Asp-box repeat
MACFILCD_00953	7.72e-279	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
MACFILCD_00954	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	exo-alpha-(2->6)-sialidase activity
MACFILCD_00956	2.28e-79	-	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
MACFILCD_00957	0.0	-	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	NAD synthase
MACFILCD_00959	5.06e-182	-	-	-	Q	-	-	-	methyltransferase activity
MACFILCD_00961	1.56e-137	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
MACFILCD_00962	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MACFILCD_00963	1.03e-195	-	-	-	-	-	-	-	-
MACFILCD_00964	1.2e-121	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	G/U mismatch-specific uracil-DNA glycosylase activity
MACFILCD_00965	5.17e-223	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
MACFILCD_00966	4.98e-117	hisI	3.5.4.19	-	E	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-AMP cyclohydrolase
MACFILCD_00967	1.18e-170	-	-	-	S	ko:K05807	-	ko00000,ko02000	Outer membrane lipoprotein
MACFILCD_00968	3.06e-115	-	-	-	S	-	-	-	Lipopolysaccharide-assembly
MACFILCD_00969	4.83e-163	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Tetrapyrrole (Corrin/Porphyrin) Methylases
MACFILCD_00970	3.77e-181	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
MACFILCD_00971	3.86e-18	-	-	-	-	-	-	-	-
MACFILCD_00972	3.73e-229	-	-	-	M	-	-	-	lytic endotransglycosylase activity
MACFILCD_00974	2.11e-272	-	-	-	S	-	-	-	regulation of ryanodine-sensitive calcium-release channel activity
MACFILCD_00976	1.39e-257	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MACFILCD_00977	0.0	-	-	-	P	ko:K07221	-	ko00000,ko02000	Phosphate-selective porin O and P
MACFILCD_00978	3.86e-162	rnc	3.1.26.3	-	K	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MACFILCD_00979	3.75e-121	actI	1.5.1.36	-	S	ko:K00484	ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220	ko00000,ko00001,ko01000	FMN binding
MACFILCD_00980	9.06e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MACFILCD_00981	8.17e-147	-	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
MACFILCD_00982	2.8e-143	-	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Cytidylate kinase
MACFILCD_00983	0.0	-	-	-	I	-	-	-	Acetyltransferase (GNAT) domain
MACFILCD_00984	5.49e-206	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MACFILCD_00985	4.34e-202	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MACFILCD_00986	0.0	-	-	-	GK	-	-	-	carbohydrate kinase activity
MACFILCD_00987	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
MACFILCD_00989	1.08e-289	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MACFILCD_00990	1.37e-129	-	-	-	D	ko:K06287	-	ko00000	Maf-like protein
MACFILCD_00991	0.0	-	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
MACFILCD_01001	6.18e-173	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	transporter
MACFILCD_01002	8.72e-235	-	-	-	CO	-	-	-	Protein of unknown function, DUF255
MACFILCD_01005	0.0	-	2.6.1.66	-	E	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
MACFILCD_01006	2.58e-196	-	-	-	S	-	-	-	Domain of unknown function (DUF1732)
MACFILCD_01007	4.39e-145	-	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
MACFILCD_01008	0.0	-	-	-	P	-	-	-	Citrate transporter
MACFILCD_01009	7.58e-209	-	-	-	J	ko:K01894	-	ko00000,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), catalytic domain
MACFILCD_01012	1.79e-216	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
MACFILCD_01013	5.46e-170	-	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
MACFILCD_01015	1.88e-250	-	-	-	-	-	-	-	-
MACFILCD_01016	3.17e-166	-	-	-	S	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
MACFILCD_01017	1.1e-173	-	-	-	T	-	-	-	Outer membrane lipoprotein-sorting protein
MACFILCD_01018	9.72e-227	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MACFILCD_01019	0.0	secD	-	-	U	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MACFILCD_01021	2.47e-273	-	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
MACFILCD_01022	1.38e-257	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
MACFILCD_01023	2.95e-262	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MACFILCD_01024	4.19e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MACFILCD_01025	1.54e-217	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Acyl transferase domain
MACFILCD_01027	1.34e-168	-	-	-	S	-	-	-	HAD-hyrolase-like
MACFILCD_01028	3.06e-286	-	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
MACFILCD_01029	3.63e-270	-	-	-	E	-	-	-	serine-type peptidase activity
MACFILCD_01030	2.03e-308	-	-	-	M	-	-	-	OmpA family
MACFILCD_01031	3.11e-216	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MACFILCD_01032	0.0	-	-	-	M	-	-	-	Peptidase M60-like family
MACFILCD_01033	8.03e-295	-	-	-	EGP	-	-	-	Major facilitator Superfamily
MACFILCD_01034	0.0	-	-	-	KT	-	-	-	Sigma factor PP2C-like phosphatases
MACFILCD_01035	7.43e-164	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
MACFILCD_01036	9.96e-244	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
MACFILCD_01037	4.16e-270	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	site-specific DNA-methyltransferase (adenine-specific) activity
MACFILCD_01038	3.24e-94	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MACFILCD_01039	0.0	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MACFILCD_01040	1.38e-174	-	-	-	NU	ko:K02457,ko:K08084	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	protein transport across the cell outer membrane
MACFILCD_01041	9.06e-189	-	-	-	-	-	-	-	-
MACFILCD_01042	2.55e-247	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
MACFILCD_01043	8.42e-184	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
MACFILCD_01044	4.94e-245	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
MACFILCD_01045	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
MACFILCD_01049	0.0	-	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
MACFILCD_01050	0.0	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MACFILCD_01051	2.77e-176	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
MACFILCD_01052	3.43e-154	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
MACFILCD_01053	7.27e-287	-	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MACFILCD_01054	6.37e-187	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MACFILCD_01056	0.0	-	-	-	T	-	-	-	pathogenesis
MACFILCD_01057	2.25e-91	-	-	-	O	-	-	-	response to oxidative stress
MACFILCD_01058	1.87e-292	-	2.3.1.31	-	E	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko01000	alpha/beta hydrolase fold
MACFILCD_01059	6.47e-29	-	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
MACFILCD_01060	0.0	-	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Glycosyltransferase family 9 (heptosyltransferase)
MACFILCD_01061	3.17e-190	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
MACFILCD_01062	0.0	-	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
MACFILCD_01063	9.83e-190	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
MACFILCD_01064	3.84e-188	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
MACFILCD_01065	0.0	-	-	-	EG	-	-	-	BNR repeat-like domain
MACFILCD_01066	0.0	legA	3.5.1.2	-	G	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	response to abiotic stimulus
MACFILCD_01067	3.96e-197	supH	-	-	Q	-	-	-	phosphatase activity
MACFILCD_01069	5.49e-85	nuoA	1.6.5.3	-	C	ko:K00330	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MACFILCD_01070	7.13e-276	-	-	-	G	-	-	-	Major Facilitator Superfamily
MACFILCD_01074	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MACFILCD_01075	2.91e-38	-	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
MACFILCD_01076	5.25e-79	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MACFILCD_01077	0.0	-	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Peptidase family M50
MACFILCD_01080	0.0	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
MACFILCD_01081	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
MACFILCD_01082	3.07e-211	MA20_36650	-	-	EG	-	-	-	spore germination
MACFILCD_01083	3.57e-190	dpnC	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Dam-replacing family
MACFILCD_01084	0.0	-	-	-	S	-	-	-	Alpha-2-macroglobulin family
MACFILCD_01085	7.9e-289	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
MACFILCD_01087	2.89e-123	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
MACFILCD_01090	1.79e-213	-	-	-	-	-	-	-	-
MACFILCD_01091	1.39e-152	-	-	-	O	-	-	-	Glycoprotease family
MACFILCD_01092	4.28e-274	-	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
MACFILCD_01094	3.86e-112	-	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MACFILCD_01095	4.12e-139	-	-	-	L	-	-	-	RNase_H superfamily
MACFILCD_01096	6.68e-103	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MACFILCD_01097	1.5e-44	-	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	RNA polymerase activity
MACFILCD_01098	3.51e-136	-	5.4.99.20	-	J	ko:K06181	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
MACFILCD_01099	4.59e-217	-	-	-	-	-	-	-	-
MACFILCD_01100	1.3e-104	-	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	NDK
MACFILCD_01101	8.2e-209	-	-	-	S	-	-	-	Glycosyltransferase like family 2
MACFILCD_01102	3.38e-224	-	-	-	M	-	-	-	Glycosyl transferase family 2
MACFILCD_01103	1.34e-07	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
MACFILCD_01104	4.02e-282	-	-	-	NU	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
MACFILCD_01105	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein E, N-terminal domain
MACFILCD_01106	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
MACFILCD_01107	5.14e-245	-	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MACFILCD_01108	2.83e-110	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
MACFILCD_01109	1.1e-280	-	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
MACFILCD_01110	0.0	murJ	-	-	S	ko:K03980	-	ko00000,ko01011,ko02000	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MACFILCD_01111	1.26e-271	-	-	-	IM	-	-	-	Cytidylyltransferase-like
MACFILCD_01112	1.74e-157	-	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Iron/manganese superoxide dismutases, alpha-hairpin domain
MACFILCD_01113	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase-like 10
MACFILCD_01114	1.47e-171	-	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
MACFILCD_01115	1.97e-190	-	-	-	L	ko:K06864	-	ko00000	tRNA processing
MACFILCD_01116	3.23e-289	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MACFILCD_01117	1.07e-238	-	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Polyprenyl synthetase
MACFILCD_01118	0.0	-	-	-	E	ko:K03305	-	ko00000	POT family
MACFILCD_01119	0.0	-	5.2.1.8	-	O	ko:K03770	-	ko00000,ko01000,ko03110	PPIC-type PPIASE domain
MACFILCD_01120	9.74e-126	-	-	-	S	-	-	-	Pfam:DUF59
MACFILCD_01121	2.59e-107	-	-	-	-	-	-	-	-
MACFILCD_01123	3.12e-219	-	-	-	E	-	-	-	Domain of unknown function (DUF3472)
MACFILCD_01124	0.0	nuoN	1.6.5.3	-	C	ko:K00343	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MACFILCD_01125	0.0	-	1.6.5.3	-	C	ko:K00342	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Proton-conducting membrane transporter
MACFILCD_01126	0.0	-	1.6.5.3	-	CP	ko:K00341	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
MACFILCD_01127	6.01e-61	nuoK	1.6.5.3	-	C	ko:K00340	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MACFILCD_01128	8.89e-156	-	1.6.5.3	-	C	ko:K00339	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone/plastoquinone oxidoreductase chain 6
MACFILCD_01129	1.8e-124	nuoI	1.6.5.3	-	C	ko:K00338	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MACFILCD_01130	1.04e-309	nuoH	1.6.5.3	-	C	ko:K00337	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MACFILCD_01131	0.0	-	1.6.5.3	-	C	ko:K00336	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
MACFILCD_01132	0.0	-	1.6.5.3	-	C	ko:K00335	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
MACFILCD_01133	2.88e-142	-	1.6.5.3	-	C	ko:K00334	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Thioredoxin-like [2Fe-2S] ferredoxin
MACFILCD_01134	1.79e-306	nuoD	1.6.5.3	-	C	ko:K00333	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MACFILCD_01136	0.0	-	-	-	G	-	-	-	Polysaccharide deacetylase
MACFILCD_01137	0.0	-	-	-	P	-	-	-	Putative Na+/H+ antiporter
MACFILCD_01138	1.25e-140	-	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Lumazine binding domain
MACFILCD_01139	2.42e-203	-	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
MACFILCD_01140	0.0	pmp21	-	-	T	-	-	-	pathogenesis
MACFILCD_01141	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
MACFILCD_01143	0.0	-	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Uncharacterized protein family UPF0004
MACFILCD_01144	0.0	-	-	-	-	ko:K07403	-	ko00000	-
MACFILCD_01145	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MACFILCD_01146	0.0	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MACFILCD_01147	1.52e-186	-	3.4.13.22	-	M	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-ala-D-ala dipeptidase
MACFILCD_01150	0.0	-	-	-	E	-	-	-	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MACFILCD_01151	0.0	-	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	tail specific protease
MACFILCD_01152	2.31e-215	-	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
MACFILCD_01153	0.0	-	3.6.4.13	-	L	ko:K03579	-	ko00000,ko01000	ATP-dependent helicase C-terminal
MACFILCD_01154	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
MACFILCD_01155	6.84e-311	-	-	-	O	-	-	-	peroxiredoxin activity
MACFILCD_01156	0.0	-	2.7.7.19	-	J	ko:K00970	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Poly A polymerase head domain
MACFILCD_01157	0.0	-	-	-	G	-	-	-	Alpha amylase, catalytic domain
MACFILCD_01158	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
MACFILCD_01159	0.0	-	-	-	-	-	-	-	-
MACFILCD_01160	7.21e-183	-	-	-	S	ko:K09778	-	ko00000	Domain of unknown function (DUF374)
MACFILCD_01161	7.21e-203	folD	1.5.1.5, 3.5.4.9	-	H	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MACFILCD_01162	8.33e-182	-	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MACFILCD_01163	1.3e-202	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MACFILCD_01164	6.93e-284	-	-	-	E	-	-	-	Transglutaminase-like superfamily
MACFILCD_01165	8.69e-261	-	-	-	J	ko:K05541	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MACFILCD_01166	1.31e-289	-	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	LytB protein
MACFILCD_01168	7.84e-42	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S20
MACFILCD_01169	2.84e-142	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MACFILCD_01170	0.0	-	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
MACFILCD_01171	1.5e-198	-	-	-	S	-	-	-	metallopeptidase activity
MACFILCD_01172	2.57e-220	-	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Phosphatidylserine decarboxylase
MACFILCD_01173	2.22e-151	-	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3 epimerase family
MACFILCD_01174	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Leucyl-tRNA synthetase, Domain 2
MACFILCD_01175	0.0	-	-	-	P	-	-	-	Sulfatase
MACFILCD_01177	7.45e-301	-	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
MACFILCD_01178	0.0	-	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
MACFILCD_01179	3.89e-267	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MACFILCD_01180	3.64e-183	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
MACFILCD_01181	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
MACFILCD_01182	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
MACFILCD_01183	0.0	rarA	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
MACFILCD_01184	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
MACFILCD_01186	9.1e-300	-	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
MACFILCD_01187	1.49e-215	-	-	-	M	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
MACFILCD_01188	2.18e-269	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
MACFILCD_01191	4.46e-127	cobU	2.7.1.156, 2.7.7.62, 6.3.5.10	-	H	ko:K02231,ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cobinamide kinase activity
MACFILCD_01192	2.17e-203	-	-	-	G	-	-	-	myo-inosose-2 dehydratase activity
MACFILCD_01193	6.86e-174	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MACFILCD_01194	2.08e-241	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MACFILCD_01195	1.11e-237	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MACFILCD_01196	0.0	cobQ	-	-	H	-	-	-	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
MACFILCD_01197	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
MACFILCD_01199	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MACFILCD_01200	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
MACFILCD_01201	6.65e-160	-	-	-	M	ko:K16079	-	ko00000,ko02000	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MACFILCD_01202	1.4e-314	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
MACFILCD_01203	0.0	-	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MACFILCD_01204	5.53e-96	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
MACFILCD_01205	1.1e-57	-	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	nucleotidyltransferase activity
MACFILCD_01206	3.09e-231	-	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
MACFILCD_01207	0.0	-	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoglutarate dehydrogenase C-terminal
MACFILCD_01208	1.48e-245	-	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit II
MACFILCD_01209	0.0	-	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
MACFILCD_01210	2.7e-113	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
MACFILCD_01211	2.34e-107	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
MACFILCD_01212	0.0	-	-	-	T	-	-	-	Chase2 domain
MACFILCD_01213	1.51e-235	-	2.7.1.221	-	S	ko:K07102	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Phosphotransferase enzyme family
MACFILCD_01214	1.25e-307	-	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MACFILCD_01215	4.98e-92	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MACFILCD_01217	1e-112	-	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Ferritin-like domain
MACFILCD_01218	0.0	-	-	-	-	-	-	-	-
MACFILCD_01219	3.15e-103	-	-	-	J	-	-	-	YjgF/chorismate_mutase-like, putative endoribonuclease
MACFILCD_01221	6.29e-115	-	-	-	S	ko:K03748	-	ko00000	DUF218 domain
MACFILCD_01223	1.97e-230	-	-	-	S	-	-	-	mannose-ethanolamine phosphotransferase activity
MACFILCD_01229	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RQC
MACFILCD_01231	3.73e-176	-	-	-	-	-	-	-	-
MACFILCD_01232	3.89e-209	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MACFILCD_01233	1.08e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MACFILCD_01234	4.43e-291	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MACFILCD_01235	5.49e-206	-	-	-	S	ko:K03453	-	ko00000	Bile acid
MACFILCD_01238	6.39e-71	-	-	-	-	-	-	-	-
MACFILCD_01239	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MACFILCD_01240	0.0	-	2.3.1.40, 6.2.1.20	-	IQ	ko:K05939	ko00071,ko00564,map00071,map00564	ko00000,ko00001,ko01000	AMP-binding enzyme
MACFILCD_01241	3.57e-26	-	-	-	T	-	-	-	pathogenesis
MACFILCD_01243	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MACFILCD_01244	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA Topoisomerase IV
MACFILCD_01245	1.37e-149	-	-	-	C	-	-	-	lactate oxidation
MACFILCD_01246	5.05e-297	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32
MACFILCD_01247	1.99e-19	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	COG0010 Arginase agmatinase formimionoglutamate hydrolase arginase family
MACFILCD_01248	0.0	-	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
MACFILCD_01249	0.0	-	-	-	C	-	-	-	cytochrome C peroxidase
MACFILCD_01250	2.31e-280	-	-	-	J	-	-	-	PFAM Endoribonuclease L-PSP
MACFILCD_01252	0.0	-	1.8.1.2	-	P	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite and sulphite reductase 4Fe-4S domain
MACFILCD_01253	1.89e-182	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MACFILCD_01254	2.4e-188	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MACFILCD_01255	6.15e-260	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
MACFILCD_01256	0.0	-	2.7.1.25, 2.7.7.4	-	P	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
MACFILCD_01257	1.73e-216	-	2.7.7.4	-	EH	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoadenosine phosphosulfate reductase family
MACFILCD_01258	8.78e-172	-	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Phosphoadenosine phosphosulfate reductase family
MACFILCD_01259	1.31e-214	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
MACFILCD_01260	8.01e-153	phoU	-	-	P	ko:K02039	-	ko00000	negative regulation of phosphate transmembrane transport
MACFILCD_01261	4.85e-185	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MACFILCD_01262	0.0	-	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MACFILCD_01263	0.0	pstC	-	-	P	ko:K02037,ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MACFILCD_01264	1.51e-221	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	PBP superfamily domain
MACFILCD_01265	6.37e-186	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MACFILCD_01266	8.65e-140	-	-	-	P	ko:K02039	-	ko00000	PhoU domain
MACFILCD_01267	2.5e-233	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
MACFILCD_01268	7.65e-101	-	-	-	M	ko:K06077	-	ko00000	Glycine zipper 2TM domain
MACFILCD_01270	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
MACFILCD_01271	3.88e-152	-	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
MACFILCD_01272	9.25e-22	-	-	-	C	-	-	-	Nitroreductase family
MACFILCD_01273	6.31e-105	-	-	-	EG	-	-	-	membrane
MACFILCD_01274	1.37e-94	-	-	-	C	-	-	-	Nitroreductase family
MACFILCD_01275	1.52e-16	-	-	-	C	-	-	-	Nitroreductase family
MACFILCD_01276	6.58e-225	-	-	-	L	-	-	-	Elongator protein 3, MiaB family, Radical SAM
MACFILCD_01277	1.44e-229	-	-	-	J	-	-	-	Belongs to the universal ribosomal protein uS2 family
MACFILCD_01278	7.2e-103	-	-	-	K	-	-	-	DNA-binding transcription factor activity
MACFILCD_01279	9.17e-70	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
MACFILCD_01280	5.11e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MACFILCD_01281	4.62e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Amino acid kinase family
MACFILCD_01282	5.98e-211	-	-	-	M	-	-	-	Mechanosensitive ion channel
MACFILCD_01283	3.6e-152	-	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
MACFILCD_01284	0.0	-	-	-	S	-	-	-	Sodium:neurotransmitter symporter family
MACFILCD_01285	0.0	-	-	-	-	-	-	-	-
MACFILCD_01286	2.37e-46	-	-	-	J	-	-	-	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MACFILCD_01287	3.08e-146	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MACFILCD_01289	1.12e-305	-	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MACFILCD_01290	9.82e-110	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07305,ko:K12267	-	ko00000,ko01000	peptide-methionine (R)-S-oxide reductase activity
MACFILCD_01291	4.16e-259	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MACFILCD_01292	1.11e-299	nupG	-	-	G	ko:K03289,ko:K03301,ko:K08218,ko:K11537	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
MACFILCD_01295	1.07e-246	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MACFILCD_01296	1.03e-243	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MACFILCD_01297	0.0	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MACFILCD_01298	5.59e-227	-	-	-	M	ko:K01993	-	ko00000	HlyD family secretion protein
MACFILCD_01299	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MACFILCD_01300	3.85e-194	-	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	CDP-alcohol phosphatidyltransferase
MACFILCD_01301	4.03e-120	-	-	-	-	-	-	-	-
MACFILCD_01302	2.15e-198	-	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MACFILCD_01303	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
MACFILCD_01304	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GcpE protein
MACFILCD_01305	2.7e-147	-	-	-	IQ	-	-	-	RmlD substrate binding domain
MACFILCD_01306	9.61e-290	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
MACFILCD_01307	0.0	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	thiolester hydrolase activity
MACFILCD_01308	1.15e-281	-	-	-	IQ	-	-	-	Beta-ketoacyl synthase, C-terminal domain
MACFILCD_01309	9.45e-261	-	2.3.1.47	-	H	ko:K00652	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MACFILCD_01313	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MACFILCD_01314	2.46e-309	-	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
MACFILCD_01315	3.54e-176	hypB	-	-	KO	ko:K04652	-	ko00000,ko03110	CobW/HypB/UreG, nucleotide-binding domain
MACFILCD_01316	0.0	-	-	-	O	ko:K04656	-	ko00000	HypF finger
MACFILCD_01317	3.9e-50	-	-	-	O	ko:K04653	-	ko00000	HupF/HypC family
MACFILCD_01318	1.91e-262	-	-	-	O	ko:K04654	-	ko00000	Hydrogenase formation hypA family
MACFILCD_01319	3.59e-241	-	-	-	O	ko:K04655	-	ko00000	AIR synthase related protein, N-terminal domain
MACFILCD_01320	1.14e-279	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
MACFILCD_01321	0.0	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
MACFILCD_01322	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	MreB/Mbl protein
MACFILCD_01323	2.2e-61	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MACFILCD_01324	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MACFILCD_01325	5.31e-99	-	-	-	S	-	-	-	peptidase
MACFILCD_01326	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
MACFILCD_01330	8.04e-298	-	-	-	-	-	-	-	-
MACFILCD_01331	0.0	-	-	-	D	-	-	-	Chain length determinant protein
MACFILCD_01332	7.55e-142	-	-	-	M	-	-	-	Polysaccharide biosynthesis/export protein
MACFILCD_01334	4.46e-148	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MACFILCD_01335	1.67e-249	-	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
MACFILCD_01336	3.33e-285	pgk	2.7.2.3	-	G	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
MACFILCD_01337	3.15e-237	-	-	-	-	-	-	-	-
MACFILCD_01338	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	myo-inosose-2 dehydratase activity
MACFILCD_01339	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
MACFILCD_01340	0.0	-	-	-	L	-	-	-	TRCF
MACFILCD_01341	1.55e-294	-	-	-	-	-	-	-	-
MACFILCD_01342	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
MACFILCD_01343	3e-254	-	-	-	S	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MACFILCD_01345	5.56e-214	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	PHP domain
MACFILCD_01346	1.4e-259	-	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphate acetyl/butaryl transferase
MACFILCD_01347	4.05e-242	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MACFILCD_01348	7.42e-75	-	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MACFILCD_01352	1.89e-100	-	-	-	MP	-	-	-	regulation of cell-substrate adhesion
MACFILCD_01356	0.0	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
MACFILCD_01357	1.83e-231	-	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
MACFILCD_01358	0.0	-	-	-	G	-	-	-	Glycogen debranching enzyme
MACFILCD_01359	0.0	-	-	-	M	-	-	-	NPCBM/NEW2 domain
MACFILCD_01360	0.0	-	-	-	M	ko:K04744	-	ko00000,ko02000	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MACFILCD_01361	2.94e-155	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
MACFILCD_01362	1.07e-192	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
MACFILCD_01363	1.06e-169	-	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
MACFILCD_01364	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
MACFILCD_01365	4.37e-124	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	adenylate kinase activity
MACFILCD_01366	1.25e-166	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MACFILCD_01367	0.0	-	-	-	ET	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MACFILCD_01368	4.55e-170	-	-	-	S	-	-	-	Terminase
MACFILCD_01373	2.26e-10	-	-	-	L	ko:K02315	-	ko00000,ko03032	PFAM IstB domain protein ATP-binding protein
MACFILCD_01374	3.96e-20	-	-	-	K	-	-	-	ROK family
MACFILCD_01375	6.16e-43	-	-	-	L	-	-	-	D12 class N6 adenine-specific DNA methyltransferase
MACFILCD_01378	8.3e-50	-	-	-	-	-	-	-	-
MACFILCD_01389	3.89e-74	-	-	-	KT	-	-	-	Peptidase S24-like
MACFILCD_01391	8.3e-12	-	-	-	-	-	-	-	-
MACFILCD_01393	8.26e-07	-	-	-	L	-	-	-	Excalibur calcium-binding domain
MACFILCD_01395	5.68e-30	-	-	-	D	-	-	-	Phage minor structural protein
MACFILCD_01402	1.35e-18	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
MACFILCD_01404	1.24e-130	-	-	-	S	-	-	-	Glycosyl hydrolase 108
MACFILCD_01411	5.5e-33	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MACFILCD_01413	2.9e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Semialdehyde dehydrogenase, NAD binding domain
MACFILCD_01414	6.21e-304	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MACFILCD_01415	1.44e-110	-	-	-	S	-	-	-	Putative zinc- or iron-chelating domain
MACFILCD_01416	5.42e-30	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
MACFILCD_01418	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	ATPases associated with a variety of cellular activities
MACFILCD_01419	4e-147	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
MACFILCD_01420	1.14e-126	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
MACFILCD_01421	1.73e-249	-	-	-	-	-	-	-	-
MACFILCD_01423	4.5e-176	-	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
MACFILCD_01424	3.65e-60	-	-	-	S	ko:K09131	-	ko00000	DUF167
MACFILCD_01425	1.72e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MACFILCD_01426	1.2e-262	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MACFILCD_01427	1.1e-174	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MACFILCD_01428	2.96e-242	-	3.1.3.18	-	F	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
MACFILCD_01429	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
MACFILCD_01430	1.18e-227	-	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
MACFILCD_01431	0.0	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Peptidase S24-like
MACFILCD_01432	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
MACFILCD_01433	6.29e-151	-	-	-	-	-	-	-	-
MACFILCD_01434	5.71e-165	pks6	-	-	Q	-	-	-	amino acid activation for nonribosomal peptide biosynthetic process
MACFILCD_01435	1.76e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF3485)
MACFILCD_01436	1.97e-228	-	-	-	C	-	-	-	Transmembrane exosortase (Exosortase_EpsH)
MACFILCD_01437	1.31e-219	prs	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MACFILCD_01438	3.56e-131	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MACFILCD_01440	1.48e-141	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
MACFILCD_01441	3.6e-145	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MACFILCD_01442	1.56e-60	-	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S6
MACFILCD_01443	8.87e-212	-	1.1.1.262	-	H	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal phosphate biosynthetic protein PdxA
MACFILCD_01446	9.66e-224	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
MACFILCD_01447	1.1e-254	-	2.7.1.11, 2.7.1.90	-	G	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Phosphofructokinase
MACFILCD_01448	1.38e-219	-	-	-	L	-	-	-	Membrane
MACFILCD_01449	0.0	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
MACFILCD_01451	1.04e-109	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MACFILCD_01452	8.76e-126	-	-	-	-	-	-	-	-
MACFILCD_01453	0.0	-	-	-	U	ko:K03321	-	ko00000,ko02000	Sulfate permease family
MACFILCD_01454	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase C-terminal
MACFILCD_01455	2.05e-162	-	-	-	S	-	-	-	SWIM zinc finger
MACFILCD_01456	0.0	-	-	-	-	-	-	-	-
MACFILCD_01457	2.46e-307	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MACFILCD_01458	4.2e-204	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MACFILCD_01459	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
MACFILCD_01460	1.9e-257	-	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
MACFILCD_01461	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
MACFILCD_01462	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MACFILCD_01463	6.96e-305	-	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	tRNA (Uracil-5-)-methyltransferase
MACFILCD_01466	0.0	-	-	-	-	-	-	-	-
MACFILCD_01467	7.36e-55	himA	-	-	L	ko:K03530,ko:K04764,ko:K05788	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
MACFILCD_01468	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
MACFILCD_01469	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
MACFILCD_01470	1.33e-110	-	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
MACFILCD_01471	0.0	-	-	-	T	-	-	-	Histidine kinase
MACFILCD_01472	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
MACFILCD_01473	1.52e-188	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
MACFILCD_01474	3.8e-43	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	CTP reductase activity
MACFILCD_01475	0.0	-	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
MACFILCD_01476	0.0	-	-	-	M	-	-	-	Glycosyl Hydrolase Family 88
MACFILCD_01477	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1705)
MACFILCD_01478	1.96e-121	ngr	-	-	C	-	-	-	Rubrerythrin
MACFILCD_01480	8.88e-268	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
MACFILCD_01481	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
MACFILCD_01482	4.93e-286	-	-	-	EGP	-	-	-	Major facilitator Superfamily
MACFILCD_01483	1.18e-276	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
MACFILCD_01484	3.06e-85	-	-	-	M	ko:K03282	-	ko00000,ko02000	Large-conductance mechanosensitive channel, MscL
MACFILCD_01485	1.95e-312	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
MACFILCD_01486	1.2e-105	-	-	-	S	-	-	-	ACT domain protein
MACFILCD_01487	9.29e-132	-	-	-	J	ko:K02356	-	ko00000,ko03012	Elongation factor P (EF-P) OB domain
MACFILCD_01488	2.85e-245	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
MACFILCD_01489	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
MACFILCD_01490	0.0	-	-	-	L	ko:K03631	-	ko00000,ko03400	RecF/RecN/SMC N terminal domain
MACFILCD_01491	3.71e-190	-	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Metallo-beta-lactamase superfamily
MACFILCD_01492	1.45e-191	-	-	-	M	-	-	-	Glycosyl transferase WecB/TagA/CpsF family
MACFILCD_01493	1.76e-170	yyaQ	-	-	V	-	-	-	Protein conserved in bacteria
MACFILCD_01494	1.9e-90	-	-	-	-	-	-	-	-
MACFILCD_01497	1.35e-205	-	-	-	S	ko:K09949	-	ko00000	Protein of unknown function (DUF1009)
MACFILCD_01498	1.63e-298	-	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
MACFILCD_01499	9.47e-236	-	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
MACFILCD_01500	6.82e-223	-	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
MACFILCD_01501	2.52e-197	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MACFILCD_01502	3.51e-243	-	-	-	M	ko:K18094	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	Biotin-lipoyl like
MACFILCD_01503	0.0	-	-	-	V	ko:K18095	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	AcrB/AcrD/AcrF family
MACFILCD_01504	0.0	-	-	-	S	-	-	-	pathogenesis
MACFILCD_01505	3.48e-98	-	-	-	S	-	-	-	peptidase
MACFILCD_01506	3e-171	-	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
MACFILCD_01507	6.42e-101	-	-	-	S	-	-	-	peptidase
MACFILCD_01508	0.0	-	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase HemD
MACFILCD_01509	7.84e-101	-	-	-	-	-	-	-	-
MACFILCD_01510	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Bacterial DNA topoisomeraes I ATP-binding domain
MACFILCD_01514	8.8e-169	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
MACFILCD_01515	0.0	-	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
MACFILCD_01516	2.93e-125	-	-	-	D	-	-	-	ErfK ybiS ycfS ynhG family protein
MACFILCD_01518	1.77e-284	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MACFILCD_01521	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
MACFILCD_01522	1.17e-271	-	-	-	S	-	-	-	tRNA-splicing ligase RtcB
MACFILCD_01523	2.75e-214	-	-	-	K	-	-	-	LysR substrate binding domain
MACFILCD_01524	3.53e-295	-	-	-	EGP	-	-	-	Major facilitator Superfamily
MACFILCD_01526	7.1e-130	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
MACFILCD_01527	6.52e-75	-	-	-	L	-	-	-	Cupin 2, conserved barrel domain protein
MACFILCD_01528	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	subunit M
MACFILCD_01529	1.32e-196	-	-	-	V	-	-	-	AAA domain
MACFILCD_01530	3.86e-122	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MACFILCD_01531	0.0	hsdR	3.1.21.3	-	F	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MACFILCD_01532	4.61e-19	-	-	-	-	-	-	-	-
MACFILCD_01533	1.71e-27	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
MACFILCD_01534	4.16e-14	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
MACFILCD_01535	1.14e-161	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MACFILCD_01537	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MACFILCD_01539	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Collagenase
MACFILCD_01540	2.54e-285	-	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
MACFILCD_01542	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MACFILCD_01543	0.0	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 Helicase protein
MACFILCD_01544	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
MACFILCD_01545	1.77e-124	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
MACFILCD_01546	4.2e-208	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MACFILCD_01547	1.53e-47	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S L24/mitochondrial 39S L24
MACFILCD_01548	5.36e-138	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MACFILCD_01549	1.66e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MACFILCD_01550	2.25e-105	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MACFILCD_01551	2.38e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MACFILCD_01552	3.38e-102	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MACFILCD_01553	6.42e-101	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
MACFILCD_01555	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MACFILCD_01556	6.41e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MACFILCD_01557	1.29e-192	map	3.4.11.18	-	J	ko:K01265	-	ko00000,ko01000,ko01002	Metallopeptidase family M24
MACFILCD_01558	8.13e-264	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
MACFILCD_01559	0.0	-	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
MACFILCD_01560	0.0	-	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Polyphosphate kinase middle domain
MACFILCD_01561	1.02e-281	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
MACFILCD_01563	8.96e-274	-	-	GT2	S	ko:K19427	-	ko00000,ko01000	PFAM glycosyl transferase family 2
MACFILCD_01564	3.06e-226	-	-	-	S	-	-	-	Glycosyl transferase family 11
MACFILCD_01565	4.88e-263	-	-	-	S	-	-	-	Glycosyltransferase like family 2
MACFILCD_01566	3.23e-290	-	-	-	-	-	-	-	-
MACFILCD_01567	2.16e-265	-	-	-	S	-	-	-	PFAM glycosyl transferase family 2
MACFILCD_01568	3.93e-128	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MACFILCD_01569	6.83e-231	-	-	-	C	-	-	-	e3 binding domain
MACFILCD_01570	4.34e-284	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MACFILCD_01571	4.05e-135	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MACFILCD_01572	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
MACFILCD_01573	0.0	-	-	-	T	-	-	-	5TM C-terminal transporter carbon starvation CstA
MACFILCD_01574	2.76e-151	-	-	-	-	-	-	-	-
MACFILCD_01575	0.0	-	-	-	P	-	-	-	PA14 domain
MACFILCD_01576	2e-82	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MACFILCD_01577	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MACFILCD_01578	5.58e-289	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	NusA-like KH domain
MACFILCD_01579	3.73e-195	-	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
MACFILCD_01580	7.02e-144	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MACFILCD_01581	1.49e-135	-	-	-	J	-	-	-	Putative rRNA methylase
MACFILCD_01582	1.63e-203	-	-	-	S	-	-	-	Domain of unknown function (DUF362)
MACFILCD_01583	0.0	-	-	-	C	-	-	-	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein
MACFILCD_01584	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
MACFILCD_01586	0.0	-	-	-	-	-	-	-	-
MACFILCD_01587	1.44e-184	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
MACFILCD_01588	6.02e-142	-	-	-	S	-	-	-	RNA recognition motif
MACFILCD_01589	0.0	-	-	-	M	-	-	-	Bacterial sugar transferase
MACFILCD_01590	8.88e-284	-	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Galactokinase galactose-binding signature
MACFILCD_01591	0.0	-	-	-	S	ko:K03307	-	ko00000	Sodium:solute symporter family
MACFILCD_01593	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
MACFILCD_01594	3.02e-227	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MACFILCD_01595	9.27e-271	-	-	-	M	-	-	-	Monogalactosyldiacylglycerol (MGDG) synthase
MACFILCD_01596	7.16e-174	coaX	2.7.1.33	-	K	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Type III pantothenate kinase
MACFILCD_01597	8.56e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
MACFILCD_01598	3.5e-132	-	-	-	-	-	-	-	-
MACFILCD_01599	5.19e-178	-	-	-	S	-	-	-	Lysin motif
MACFILCD_01600	5.31e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MACFILCD_01601	4.21e-54	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
MACFILCD_01603	1.42e-105	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
MACFILCD_01604	3.4e-206	-	-	-	M	-	-	-	self proteolysis
MACFILCD_01607	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
MACFILCD_01608	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
MACFILCD_01609	1.73e-221	-	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Glutaminase
MACFILCD_01610	2.43e-95	-	-	-	K	-	-	-	-acetyltransferase
MACFILCD_01611	5.82e-308	-	-	-	E	ko:K03310	-	ko00000	Sodium:alanine symporter family
MACFILCD_01613	3.95e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MACFILCD_01614	1.16e-213	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MACFILCD_01615	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MACFILCD_01616	1.25e-199	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MACFILCD_01620	4.33e-161	menG	2.1.1.163, 2.1.1.201	-	Q	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	ubiE/COQ5 methyltransferase family
MACFILCD_01621	0.0	-	-	-	V	-	-	-	MatE
MACFILCD_01623	1.76e-164	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
MACFILCD_01624	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
MACFILCD_01625	0.0	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
MACFILCD_01626	5.64e-227	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
MACFILCD_01627	2.47e-101	-	-	-	-	-	-	-	-
MACFILCD_01628	1.77e-191	-	-	-	P	ko:K09820	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MACFILCD_01629	3.84e-180	-	-	-	P	ko:K09819	-	ko00000,ko00002,ko02000	FecCD transport family
MACFILCD_01630	5.46e-126	-	-	-	S	ko:K19411	-	ko00000	UvrB/uvrC motif
MACFILCD_01631	8.21e-246	-	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	ATP:guanido phosphotransferase, C-terminal catalytic domain
MACFILCD_01632	0.0	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
MACFILCD_01633	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-L-fucosidase
MACFILCD_01634	9.98e-75	-	-	-	P	ko:K03972	-	ko00000	Rhodanese Homology Domain
MACFILCD_01635	6.54e-205	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
MACFILCD_01636	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
MACFILCD_01637	2.57e-223	-	-	-	CO	-	-	-	amine dehydrogenase activity
MACFILCD_01638	8.39e-89	-	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
MACFILCD_01639	3.69e-166	-	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
MACFILCD_01640	2.95e-203	-	-	-	GM	-	-	-	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MACFILCD_01641	3.19e-109	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
MACFILCD_01642	6.9e-232	-	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (W and Y)
MACFILCD_01643	1.56e-103	-	-	-	T	-	-	-	Universal stress protein family
MACFILCD_01644	3.41e-189	-	-	-	S	ko:K09769	-	ko00000	YmdB-like protein
MACFILCD_01645	7.14e-185	-	-	-	H	ko:K22132	-	ko00000,ko03016	ThiF family
MACFILCD_01646	3.45e-121	-	-	-	-	-	-	-	-
MACFILCD_01648	1.23e-47	-	-	-	S	-	-	-	Protease prsW family
MACFILCD_01649	2.01e-05	-	-	-	-	-	-	-	-
MACFILCD_01654	6.17e-27	-	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
MACFILCD_01655	1.03e-293	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
MACFILCD_01656	3.74e-228	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MACFILCD_01657	8.88e-122	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
MACFILCD_01658	3.77e-289	kbl	2.3.1.29	-	E	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
MACFILCD_01659	0.0	-	-	-	KLT	-	-	-	Sulfatase-modifying factor enzyme 1
MACFILCD_01660	1.06e-182	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
MACFILCD_01661	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
MACFILCD_01667	4.07e-52	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
MACFILCD_01668	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MACFILCD_01669	0.0	-	-	-	M	ko:K02847,ko:K13009,ko:K16705	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
MACFILCD_01670	8.67e-85	-	-	-	S	-	-	-	Protein of unknown function, DUF488
MACFILCD_01671	2.07e-235	-	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Porphobilinogen deaminase, dipyromethane cofactor binding domain
MACFILCD_01672	2.33e-239	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Glutamyl-tRNAGlu reductase, N-terminal domain
MACFILCD_01673	1.19e-177	-	-	-	S	-	-	-	Cytochrome C assembly protein
MACFILCD_01674	3.84e-189	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Type I GTP cyclohydrolase folE2
MACFILCD_01675	4.52e-49	-	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S18
MACFILCD_01676	5.67e-33	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
MACFILCD_01677	1.46e-118	-	-	-	T	-	-	-	Prokaryotic dksA/traR C4-type zinc finger
MACFILCD_01678	1.69e-231	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MACFILCD_01679	1.16e-244	sun	2.1.1.176, 2.1.1.178	-	J	ko:K03500,ko:K11392	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MACFILCD_01680	1.03e-121	-	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MACFILCD_01681	2.34e-97	nudI	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	GDP-mannose mannosyl hydrolase activity
MACFILCD_01683	2.88e-283	-	-	-	M	ko:K02005	-	ko00000	HlyD family secretion protein
MACFILCD_01684	2.12e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MACFILCD_01685	3.42e-313	-	-	-	V	-	-	-	MacB-like periplasmic core domain
MACFILCD_01686	3.64e-316	-	-	-	MU	-	-	-	Outer membrane efflux protein
MACFILCD_01687	6.41e-284	-	-	-	V	-	-	-	Beta-lactamase
MACFILCD_01688	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MACFILCD_01689	1.16e-280	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MACFILCD_01690	2.91e-94	-	-	-	K	-	-	-	DNA-binding transcription factor activity
MACFILCD_01691	1.45e-164	-	-	-	S	-	-	-	Uncharacterised protein family UPF0066
MACFILCD_01692	5.56e-306	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydro-orotase-like
MACFILCD_01693	3.12e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
MACFILCD_01694	1.15e-122	-	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Phosphoribosyl transferase domain
MACFILCD_01695	3.73e-90	-	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR carboxylase
MACFILCD_01697	0.0	-	-	-	H	ko:K07137	-	ko00000	5-formyltetrahydrofolate cyclo-ligase activity
MACFILCD_01698	2.63e-267	-	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
MACFILCD_01699	2.11e-89	-	-	-	-	-	-	-	-
MACFILCD_01700	0.0	rseP	3.4.21.116	-	M	ko:K06399,ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	metalloendopeptidase activity
MACFILCD_01701	1.7e-297	-	-	-	S	-	-	-	AI-2E family transporter
MACFILCD_01702	0.0	-	-	-	P	-	-	-	Domain of unknown function
MACFILCD_01704	2.25e-111	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
MACFILCD_01705	4.75e-314	-	-	-	G	-	-	-	cellulose 1,4-beta-cellobiosidase activity
MACFILCD_01706	2.72e-186	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MACFILCD_01708	1.83e-74	-	-	-	-	-	-	-	-
MACFILCD_01709	0.0	-	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	DNA Topoisomerase IV
MACFILCD_01712	7.47e-132	-	-	-	S	-	-	-	Glycosyl hydrolase 108
MACFILCD_01715	1.24e-200	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
MACFILCD_01716	5.91e-234	-	-	-	S	-	-	-	Peptidase family M28
MACFILCD_01717	0.0	-	-	-	M	-	-	-	Aerotolerance regulator N-terminal
MACFILCD_01718	0.0	-	-	-	S	-	-	-	Large extracellular alpha-helical protein
MACFILCD_01721	9.48e-237	-	-	-	S	ko:K14347	-	ko00000,ko02000,ko04147	SBF-like CPA transporter family (DUF4137)
MACFILCD_01722	1.59e-273	-	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	tRNA synthetases class I (W and Y)
MACFILCD_01724	6.05e-86	-	-	-	S	ko:K09922	-	ko00000	Putative member of DMT superfamily (DUF486)
MACFILCD_01725	1.87e-212	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
MACFILCD_01726	6.51e-217	-	-	-	EP	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MACFILCD_01727	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MACFILCD_01728	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
MACFILCD_01729	1.53e-219	-	-	-	O	-	-	-	Thioredoxin-like domain
MACFILCD_01730	1.86e-310	-	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase C-terminal domain
MACFILCD_01731	7.11e-235	-	-	-	S	ko:K01128	-	ko00000,ko01000	acid phosphatase activity
MACFILCD_01734	0.0	-	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Tubulin/FtsZ family, GTPase domain
MACFILCD_01735	3.38e-294	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MACFILCD_01736	1.72e-147	-	-	-	M	-	-	-	NLP P60 protein
MACFILCD_01737	0.0	-	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
MACFILCD_01738	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
MACFILCD_01739	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
MACFILCD_01740	0.0	-	-	-	H	-	-	-	NAD synthase
MACFILCD_01741	4.54e-173	-	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease MlaE
MACFILCD_01742	1.75e-189	-	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MACFILCD_01743	3.28e-232	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MlaD protein
MACFILCD_01744	2.69e-38	-	-	-	T	-	-	-	ribosome binding
MACFILCD_01747	5.1e-265	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
MACFILCD_01748	3.71e-260	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
MACFILCD_01749	3.36e-248	ppiD	5.2.1.8	-	O	ko:K03769,ko:K03770,ko:K03771,ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl cis-trans isomerase activity
MACFILCD_01751	0.0	-	-	-	-	-	-	-	-
MACFILCD_01752	2.4e-180	kdsB	2.7.7.38	-	M	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MACFILCD_01753	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MACFILCD_01754	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
MACFILCD_01755	2.44e-312	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
MACFILCD_01756	6.39e-119	-	-	-	T	-	-	-	STAS domain
MACFILCD_01757	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2851)
MACFILCD_01758	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
MACFILCD_01759	1.79e-289	-	-	-	-	-	-	-	-
MACFILCD_01760	0.0	-	-	-	M	-	-	-	Sulfatase
MACFILCD_01761	1.4e-287	-	4.1.99.19	-	H	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Biotin and Thiamin Synthesis associated domain
MACFILCD_01762	1.39e-206	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
MACFILCD_01763	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MACFILCD_01764	3.35e-77	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	COG0732 Restriction endonuclease S subunits
MACFILCD_01765	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MACFILCD_01767	6.81e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3847)
MACFILCD_01768	0.0	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Dehydratase family
MACFILCD_01769	2.81e-167	-	-	-	T	ko:K07657	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MACFILCD_01770	4.97e-290	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
MACFILCD_01771	2.09e-10	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
MACFILCD_01772	3.88e-207	hisG	2.4.2.17	-	E	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
MACFILCD_01773	2.04e-314	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
MACFILCD_01774	4.87e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF3313)
MACFILCD_01775	7.19e-261	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MACFILCD_01776	5.43e-255	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
MACFILCD_01777	2.8e-169	-	-	-	-	-	-	-	-
MACFILCD_01778	0.0	-	-	-	NU	-	-	-	Type IV pilus assembly protein PilM;
MACFILCD_01779	1.06e-208	-	-	-	-	-	-	-	-
MACFILCD_01780	2.27e-245	-	-	-	-	-	-	-	-
MACFILCD_01781	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
MACFILCD_01782	1.85e-142	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MACFILCD_01783	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MACFILCD_01784	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
MACFILCD_01785	1.65e-240	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MACFILCD_01786	1.1e-131	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MACFILCD_01787	5.44e-229	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MACFILCD_01788	0.0	-	1.11.1.5	-	P	ko:K00428	-	ko00000,ko01000	Di-haem cytochrome c peroxidase
MACFILCD_01789	2.48e-40	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
MACFILCD_01790	4.02e-48	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
MACFILCD_01791	0.0	-	-	-	P	ko:K04759	-	ko00000,ko02000	Ferrous iron transport protein B C terminus
MACFILCD_01794	2.83e-303	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
MACFILCD_01796	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
MACFILCD_01797	4.92e-90	-	-	-	K	-	-	-	Helix-turn-helix diphteria tox regulatory element
MACFILCD_01798	4.56e-206	-	3.1.1.53	-	L	ko:K03547,ko:K05970	-	ko00000,ko01000,ko03400	3'-5' exonuclease activity
MACFILCD_01799	2.86e-133	-	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	SpoU rRNA Methylase family
MACFILCD_01800	0.0	-	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
MACFILCD_01801	9.76e-258	-	-	-	S	-	-	-	Glycoside-hydrolase family GH114
MACFILCD_01802	3.86e-304	-	-	-	M	-	-	-	Glycosyl transferases group 1
MACFILCD_01804	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RecQ zinc-binding
MACFILCD_01805	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
MACFILCD_01806	3.53e-226	-	-	-	-	-	-	-	-
MACFILCD_01807	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
MACFILCD_01808	5.14e-246	-	-	-	-	-	-	-	-
MACFILCD_01809	3.5e-249	rgpB	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MACFILCD_01810	0.0	ahcY	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MACFILCD_01811	2.18e-290	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MACFILCD_01812	1.36e-214	-	-	-	KQ	-	-	-	Hypothetical methyltransferase
MACFILCD_01815	0.0	-	-	-	E	-	-	-	PFAM major facilitator superfamily MFS_1
MACFILCD_01816	1.83e-205	-	-	-	G	ko:K06867,ko:K07001	-	ko00000	response to abiotic stimulus
MACFILCD_01818	7.45e-296	-	-	-	MU	ko:K15725	-	ko00000,ko02000	efflux transmembrane transporter activity
MACFILCD_01819	6.53e-296	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MACFILCD_01820	0.0	-	-	-	P	ko:K07239	-	ko00000	AcrB/AcrD/AcrF family
MACFILCD_01821	3.44e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MACFILCD_01823	5.61e-168	-	-	-	CO	-	-	-	Protein conserved in bacteria
MACFILCD_01824	2.6e-231	-	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
MACFILCD_01825	3.01e-153	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
MACFILCD_01826	0.0	-	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Surface antigen
MACFILCD_01827	2.93e-282	tig	-	-	O	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MACFILCD_01828	1.02e-152	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MACFILCD_01829	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MACFILCD_01830	1.44e-255	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MACFILCD_01832	9.94e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MACFILCD_01834	3.61e-46	-	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecE/Sec61-gamma subunits of protein translocation complex
MACFILCD_01835	6.29e-135	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
MACFILCD_01836	2.58e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MACFILCD_01837	8.25e-155	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MACFILCD_01838	9.92e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MACFILCD_01839	3.69e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MACFILCD_01841	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MACFILCD_01849	1.23e-187	-	5.2.1.8	-	O	ko:K03773	-	ko00000,ko01000,ko03110	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
MACFILCD_01850	4.4e-138	-	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MACFILCD_01851	1.42e-271	-	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
MACFILCD_01852	2.54e-208	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MACFILCD_01853	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
MACFILCD_01854	1.2e-167	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
MACFILCD_01860	7.72e-133	panZ	-	-	K	-	-	-	-acetyltransferase
MACFILCD_01861	1.96e-224	-	-	-	E	ko:K00612	-	ko00000,ko01000	lipolytic protein G-D-S-L family
MACFILCD_01862	1.02e-220	-	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
MACFILCD_01863	0.0	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
MACFILCD_01864	5.5e-176	-	-	-	-	-	-	-	-
MACFILCD_01866	4.49e-241	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MACFILCD_01867	2.63e-208	-	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Polyprenyl synthetase
MACFILCD_01868	1.19e-199	-	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
MACFILCD_01869	3.45e-157	-	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
MACFILCD_01870	1.42e-210	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
MACFILCD_01871	0.0	-	-	-	G	-	-	-	Trehalase
MACFILCD_01872	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MACFILCD_01873	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MACFILCD_01874	1.1e-34	-	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
MACFILCD_01875	4.9e-76	-	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	Ribonuclease P
MACFILCD_01876	4.61e-61	-	-	-	S	ko:K08998	-	ko00000	Haemolytic
MACFILCD_01877	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
MACFILCD_01878	0.0	-	1.4.1.13, 1.4.1.14	-	E	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
MACFILCD_01879	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MACFILCD_01880	0.0	-	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MACFILCD_01881	1.09e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase small chain, CPSase domain
MACFILCD_01882	6.96e-265	-	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MACFILCD_01883	1.03e-265	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
MACFILCD_01884	1.45e-296	-	-	-	C	-	-	-	Na+/H+ antiporter family
MACFILCD_01885	1.11e-236	-	-	-	-	-	-	-	-
MACFILCD_01886	4.84e-229	-	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphomannose isomerase type I
MACFILCD_01887	1.29e-181	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
MACFILCD_01888	5.31e-115	ispF	4.6.1.12	-	I	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MACFILCD_01889	8.31e-186	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
MACFILCD_01890	0.0	-	-	-	M	-	-	-	PFAM glycosyl transferase family 51
MACFILCD_01891	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
MACFILCD_01892	1.26e-96	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
MACFILCD_01893	8.63e-181	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
MACFILCD_01894	0.0	-	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MACFILCD_01895	1.27e-99	-	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Predicted SPOUT methyltransferase
MACFILCD_01896	1.67e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S9/S16
MACFILCD_01897	2.79e-97	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MACFILCD_01898	6.12e-40	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MACFILCD_01899	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MACFILCD_01900	1.69e-174	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
MACFILCD_01902	4.03e-174	-	-	-	D	-	-	-	Phage-related minor tail protein
MACFILCD_01904	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MACFILCD_01905	8.25e-63	-	-	-	L	ko:K09747	-	ko00000	YbaB/EbfC DNA-binding family
MACFILCD_01906	1.89e-253	-	-	-	N	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease Exonuclease Phosphatase
MACFILCD_01907	0.0	-	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	DHHA2
MACFILCD_01909	5.46e-189	-	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
MACFILCD_01910	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
MACFILCD_01911	0.000969	-	-	-	-	-	-	-	-
MACFILCD_01912	0.0	-	-	-	G	-	-	-	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain
MACFILCD_01916	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MACFILCD_01917	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MACFILCD_01918	7.28e-132	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MACFILCD_01919	3.88e-263	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
MACFILCD_01920	4.33e-234	-	2.7.11.1	-	T	ko:K08884,ko:K12132,ko:K20333	ko02024,map02024	ko00000,ko00001,ko01000,ko01001	PFAM Formylglycine-generating sulfatase enzyme
MACFILCD_01922	2.06e-196	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MACFILCD_01923	9.18e-137	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
MACFILCD_01924	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
MACFILCD_01925	6.35e-277	-	-	-	C	-	-	-	Aldo/keto reductase family
MACFILCD_01926	6.71e-90	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MACFILCD_01927	6.99e-260	-	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
MACFILCD_01928	1.99e-290	-	-	-	-	-	-	-	-
MACFILCD_01929	0.0	-	-	-	S	-	-	-	von Willebrand factor type A domain
MACFILCD_01930	0.0	-	-	-	S	-	-	-	Aerotolerance regulator N-terminal
MACFILCD_01931	5.75e-208	-	-	-	S	-	-	-	Protein of unknown function DUF58
MACFILCD_01932	0.0	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
MACFILCD_01933	1.78e-241	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
MACFILCD_01934	0.0	-	-	-	-	-	-	-	-
MACFILCD_01935	1.49e-237	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
MACFILCD_01936	2.1e-296	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
MACFILCD_01938	1.63e-239	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MACFILCD_01940	5.75e-202	-	-	-	O	-	-	-	stress-induced mitochondrial fusion
MACFILCD_01941	3.62e-204	-	-	-	S	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
MACFILCD_01942	1.03e-121	-	-	-	M	ko:K03098	-	ko00000,ko04147	Lipocalin-like domain
MACFILCD_01943	1.35e-236	-	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MACFILCD_01944	3.41e-188	-	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
MACFILCD_01945	1.6e-151	-	-	-	K	-	-	-	Transcriptional regulator
MACFILCD_01946	1.35e-264	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
MACFILCD_01948	0.0	-	-	-	P	-	-	-	Sulfatase
MACFILCD_01949	1.26e-79	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
MACFILCD_01950	4.6e-305	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MACFILCD_01951	0.0	-	-	-	E	-	-	-	Aminotransferase class I and II
MACFILCD_01952	3.56e-219	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MACFILCD_01953	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha galactosidase A
MACFILCD_01954	1.04e-49	-	-	-	-	-	-	-	-
MACFILCD_01955	1.45e-55	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
MACFILCD_01956	4.69e-236	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
MACFILCD_01957	2.13e-96	-	-	-	L	ko:K07447	-	ko00000,ko01000	Likely ribonuclease with RNase H fold.
MACFILCD_01958	9.8e-259	-	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
MACFILCD_01959	2.5e-172	-	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MACFILCD_01960	0.0	-	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	TopoisomeraseII
MACFILCD_01961	8.53e-211	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
MACFILCD_01963	0.0	-	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	HELICc2
MACFILCD_01964	2.79e-178	cbiO	-	-	P	ko:K02006,ko:K02008,ko:K16784,ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase activity
MACFILCD_01965	2.32e-193	cbiQ	-	-	P	ko:K02007,ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transmembrane transporter activity
MACFILCD_01966	8.77e-239	cbiM	-	-	P	ko:K02007,ko:K02009,ko:K16915	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt ion transport
MACFILCD_01968	8.06e-18	-	-	-	S	-	-	-	Lipocalin-like
MACFILCD_01969	3.2e-209	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
MACFILCD_01970	1.05e-226	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MACFILCD_01971	1.06e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L9, N-terminal domain
MACFILCD_01972	0.0	-	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT/IMPCHase bienzyme
MACFILCD_01973	1.33e-171	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MACFILCD_01974	9.05e-85	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	4'-phosphopantetheinyl transferase superfamily
MACFILCD_01976	0.0	pckG	4.1.1.32	-	C	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
MACFILCD_01977	1.15e-165	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
MACFILCD_01978	0.0	-	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	RecG wedge domain
MACFILCD_01980	0.0	-	-	-	C	ko:K00184	-	ko00000	4Fe-4S dicluster domain
MACFILCD_01981	2.16e-180	-	-	-	C	-	-	-	Cytochrome c7 and related cytochrome c
MACFILCD_01982	2.09e-302	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MACFILCD_01984	6.34e-255	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Iron-containing alcohol dehydrogenase
MACFILCD_01988	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Prolyl-tRNA synthetase, C-terminal
MACFILCD_01989	2.04e-158	-	-	-	S	-	-	-	Peptidase family M50
MACFILCD_01991	3.93e-216	-	-	-	JM	-	-	-	Nucleotidyl transferase
MACFILCD_01992	2.88e-273	-	-	-	S	-	-	-	Phosphotransferase enzyme family
MACFILCD_01993	3.51e-223	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
MACFILCD_01995	0.0	-	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
MACFILCD_01996	5.87e-296	-	-	-	-	-	-	-	-
MACFILCD_01997	0.0	-	-	-	-	-	-	-	-
MACFILCD_01998	8.84e-140	mntP	-	-	P	-	-	-	manganese ion transmembrane transporter activity
MACFILCD_02000	4.87e-189	-	-	-	S	-	-	-	Phenazine biosynthesis-like protein
MACFILCD_02001	2.32e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MACFILCD_02002	1.48e-308	-	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, Activator interacting domain (AID)
MACFILCD_02003	2.23e-272	ycaD	-	-	EGP	ko:K08219	-	ko00000,ko02000	Major facilitator Superfamily
MACFILCD_02004	6.79e-222	-	3.4.11.10, 3.4.11.6	-	DZ	ko:K19701	-	ko00000,ko01000,ko01002	aminopeptidase activity
MACFILCD_02005	1.16e-287	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
MACFILCD_02006	0.0	-	-	-	S	-	-	-	inositol 2-dehydrogenase activity
MACFILCD_02008	1.88e-274	-	3.6.4.13	-	L	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	helicase superfamily c-terminal domain
MACFILCD_02010	3.6e-145	-	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
MACFILCD_02011	0.0	-	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MACFILCD_02012	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
MACFILCD_02013	3.98e-277	-	4.2.1.51, 5.4.99.5	-	E	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
MACFILCD_02014	3.72e-237	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MACFILCD_02015	1.57e-190	-	-	-	S	-	-	-	NIF3 (NGG1p interacting factor 3)
MACFILCD_02016	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
MACFILCD_02017	0.0	-	-	-	N	-	-	-	ABC-type uncharacterized transport system
MACFILCD_02018	2.49e-183	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MACFILCD_02019	1.09e-223	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MACFILCD_02020	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MACFILCD_02021	2.38e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	nUDIX hydrolase
MACFILCD_02023	3.58e-251	-	2.3.1.1	-	E	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
MACFILCD_02024	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MACFILCD_02025	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MACFILCD_02027	1.23e-175	-	6.3.5.11, 6.3.5.9	-	V	ko:K02224,ko:K18554	ko00860,ko01100,ko01120,map00860,map01100,map01120	br01600,ko00000,ko00001,ko01000,ko01504	Chloramphenicol phosphotransferase-like protein
MACFILCD_02028	5.74e-86	-	-	-	K	ko:K07343	-	ko00000	positive regulation of type IV pilus biogenesis
MACFILCD_02029	2.86e-226	-	-	-	CO	-	-	-	Redoxin
MACFILCD_02030	1.73e-123	paiA	-	-	K	-	-	-	acetyltransferase
MACFILCD_02031	1.87e-215	-	-	-	K	-	-	-	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
MACFILCD_02033	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
MACFILCD_02036	0.0	-	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
MACFILCD_02037	0.0	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
MACFILCD_02038	1.69e-06	-	-	-	-	-	-	-	-
MACFILCD_02039	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
MACFILCD_02040	0.0	-	-	-	S	ko:K07126,ko:K13582	ko04112,map04112	ko00000,ko00001	beta-lactamase activity
MACFILCD_02042	5.88e-279	-	6.2.1.26	-	IQ	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	AMP-binding enzyme
MACFILCD_02043	1.27e-70	-	-	-	K	-	-	-	ribonuclease III activity
MACFILCD_02044	1.55e-164	-	-	-	-	-	-	-	-
MACFILCD_02045	2.1e-140	nuoC	1.6.5.3	-	C	ko:K00332	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MACFILCD_02046	6.52e-139	nuoB	1.6.5.3	-	C	ko:K00331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MACFILCD_02051	5.88e-277	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
MACFILCD_02052	1.35e-240	-	-	-	O	-	-	-	Trypsin-like peptidase domain
MACFILCD_02053	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Transglycosylase
MACFILCD_02054	5.99e-286	-	-	-	S	ko:K09760	-	ko00000	RmuC family
MACFILCD_02055	6.64e-170	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
MACFILCD_02056	1.25e-132	-	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MACFILCD_02057	5.32e-208	-	-	-	S	-	-	-	RDD family
MACFILCD_02058	0.0	-	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MacB-like periplasmic core domain
MACFILCD_02059	3.39e-210	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
MACFILCD_02060	2.64e-89	-	-	-	S	ko:K09793	-	ko00000	Protein of unknown function (DUF456)
MACFILCD_02061	4.81e-58	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MACFILCD_02062	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
MACFILCD_02063	1.46e-09	-	-	-	S	-	-	-	Peptidase family M28
MACFILCD_02064	1.17e-247	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MACFILCD_02065	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MACFILCD_02066	1.76e-186	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase (SPase) II
MACFILCD_02067	1.19e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
MACFILCD_02068	3.13e-114	-	-	-	P	-	-	-	Rhodanese-like domain
MACFILCD_02069	1.56e-297	-	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MACFILCD_02070	0.0	-	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MACFILCD_02071	0.000231	-	2.7.11.1, 2.7.11.17	-	T	ko:K08794,ko:K13412,ko:K17530	ko04626,ko04921,ko04925,ko05145,map04626,map04921,map04925,map05145	ko00000,ko00001,ko01000,ko01001	protein serine/threonine kinase activity
MACFILCD_02073	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MACFILCD_02074	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
MACFILCD_02075	4.12e-100	-	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Glyoxalase-like domain
MACFILCD_02076	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
MACFILCD_02078	3.41e-55	-	-	-	I	-	-	-	PFAM biotin lipoyl attachment domain-containing protein
MACFILCD_02079	0.0	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
MACFILCD_02080	1.35e-191	-	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
MACFILCD_02081	0.0	-	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
MACFILCD_02083	9.53e-206	-	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MACFILCD_02084	8.83e-270	-	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
MACFILCD_02085	1.13e-228	-	2.7.1.11	-	G	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Phosphofructokinase
MACFILCD_02086	2.72e-183	-	-	-	L	ko:K10800	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	uracil-dna glycosylase
MACFILCD_02087	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MACFILCD_02088	0.0	poxB	1.2.3.3, 1.2.5.1	-	EH	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
MACFILCD_02089	0.000553	-	-	-	-	-	-	-	-
MACFILCD_02090	0.0	-	-	-	G	-	-	-	alpha-galactosidase
MACFILCD_02092	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
MACFILCD_02093	2.76e-267	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MACFILCD_02094	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MACFILCD_02095	9.04e-317	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
MACFILCD_02097	1.49e-178	-	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MACFILCD_02099	2.55e-171	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
MACFILCD_02102	0.0	-	-	-	L	-	-	-	DNA restriction-modification system
MACFILCD_02104	7.18e-182	-	-	-	I	-	-	-	Acyl-ACP thioesterase
MACFILCD_02105	5.99e-231	-	4.1.1.35	-	M	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	3-beta hydroxysteroid dehydrogenase/isomerase family
MACFILCD_02106	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MACFILCD_02107	2.04e-160	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MACFILCD_02109	5.7e-236	-	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
MACFILCD_02111	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MACFILCD_02112	1.15e-146	-	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MACFILCD_02113	3.48e-43	-	-	-	K	-	-	-	-acetyltransferase
MACFILCD_02114	3.69e-297	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
MACFILCD_02115	6.64e-279	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
MACFILCD_02116	1.47e-121	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MACFILCD_02117	1.12e-63	-	-	-	J	-	-	-	RF-1 domain
MACFILCD_02118	1.01e-124	-	-	-	-	-	-	-	-
MACFILCD_02119	0.0	-	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP--glucose-1-phosphate uridylyltransferase
MACFILCD_02120	8.74e-182	-	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
MACFILCD_02122	3.44e-132	-	-	-	S	-	-	-	protein trimerization
MACFILCD_02123	2.54e-226	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
MACFILCD_02124	0.0	-	2.7.7.15	-	H	ko:K00968	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
MACFILCD_02125	7.48e-96	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
MACFILCD_02126	0.0	cobD	2.6.1.9, 2.7.7.74, 4.1.1.81	-	M	ko:K00817,ko:K04720,ko:K07281	ko00340,ko00350,ko00360,ko00400,ko00401,ko00562,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00562,map00860,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	nucleotidyl transferase
MACFILCD_02127	1.45e-262	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
MACFILCD_02128	0.0	-	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha amylase, C-terminal all-beta domain
MACFILCD_02130	5.06e-94	-	-	-	S	ko:K02426	-	ko00000	Fe-S metabolism associated domain
MACFILCD_02131	1.64e-223	-	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MACFILCD_02132	0.0	-	-	-	P	-	-	-	Sulfatase
MACFILCD_02133	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MACFILCD_02134	8.72e-53	-	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
MACFILCD_02135	3.12e-223	hprK	-	-	T	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
MACFILCD_02136	0.0	-	-	-	E	-	-	-	Peptidase dimerisation domain
MACFILCD_02137	8.83e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MACFILCD_02138	2.01e-139	-	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
MACFILCD_02139	0.0	-	-	-	S	-	-	-	50S ribosome-binding GTPase
MACFILCD_02140	1.02e-163	-	-	-	S	ko:K06997	-	ko00000	Alanine racemase, N-terminal domain
MACFILCD_02141	2.2e-134	-	-	-	K	ko:K07735	-	ko00000,ko03000	Uncharacterized ACR, COG1678
MACFILCD_02142	9e-194	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
MACFILCD_02143	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
MACFILCD_02144	7.47e-203	-	-	-	-	-	-	-	-
MACFILCD_02145	8.46e-84	-	-	-	P	ko:K06195	-	ko00000	ApaG domain
MACFILCD_02146	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
MACFILCD_02147	8.26e-106	-	-	-	K	-	-	-	Lrp/AsnC ligand binding domain
MACFILCD_02148	3.2e-286	-	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
MACFILCD_02149	1.93e-209	-	-	-	S	-	-	-	CAAX protease self-immunity
MACFILCD_02150	8.72e-155	-	-	-	S	-	-	-	DUF218 domain
MACFILCD_02151	0.0	-	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Anticodon binding domain
MACFILCD_02152	1.36e-204	yeaE	-	-	S	-	-	-	aldo-keto reductase (NADP) activity
MACFILCD_02153	0.0	-	-	-	S	-	-	-	Oxygen tolerance
MACFILCD_02154	8.51e-42	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
MACFILCD_02156	6.21e-39	-	-	-	-	-	-	-	-
MACFILCD_02157	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MACFILCD_02159	9.83e-235	-	-	-	CO	-	-	-	Thioredoxin-like
MACFILCD_02160	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
MACFILCD_02161	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
MACFILCD_02162	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
MACFILCD_02163	2.27e-75	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
MACFILCD_02164	5.74e-211	ybfH	-	-	EG	-	-	-	spore germination
MACFILCD_02165	9.28e-139	-	-	-	-	-	-	-	-
MACFILCD_02166	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MACFILCD_02167	3.62e-121	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MACFILCD_02168	7.48e-188	-	-	-	O	ko:K04083	-	ko00000,ko03110	Hsp33 protein
MACFILCD_02171	3.56e-234	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
MACFILCD_02175	1.69e-129	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
MACFILCD_02176	5.94e-178	-	4.2.99.20	-	I	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
MACFILCD_02177	1.46e-75	-	-	-	S	ko:K09954	-	ko00000	Putative quorum-sensing-regulated virulence factor
MACFILCD_02179	1.24e-51	-	-	-	-	-	-	-	-
MACFILCD_02180	2.33e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
MACFILCD_02181	3.79e-182	-	-	-	-	-	-	-	-
MACFILCD_02182	2.59e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
MACFILCD_02183	4.44e-110	-	-	-	KT	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
MACFILCD_02184	1.66e-304	-	-	-	C	-	-	-	4 iron, 4 sulfur cluster binding
MACFILCD_02185	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
MACFILCD_02186	1.55e-221	-	-	-	K	-	-	-	Transcriptional regulator
MACFILCD_02187	1.05e-178	-	-	-	C	-	-	-	aldo keto reductase
MACFILCD_02188	2.06e-186	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MACFILCD_02189	5.85e-275	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
MACFILCD_02190	5.83e-310	-	-	-	C	-	-	-	Carboxymuconolactone decarboxylase family
MACFILCD_02191	2.95e-159	-	-	-	IQ	-	-	-	Short chain dehydrogenase
MACFILCD_02192	3.57e-28	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
MACFILCD_02194	4.21e-137	-	-	-	J	ko:K05808	-	ko00000,ko03009	Sigma 54 modulation/S30EA ribosomal protein C terminus
MACFILCD_02196	4.11e-08	-	-	-	M	-	-	-	major outer membrane lipoprotein
MACFILCD_02197	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MACFILCD_02199	2.57e-170	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
MACFILCD_02200	1.58e-307	-	-	-	C	-	-	-	Sulfatase-modifying factor enzyme 1
MACFILCD_02201	1.6e-22	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MACFILCD_02203	1.15e-05	-	-	-	-	-	-	-	-
MACFILCD_02205	7.45e-49	XK27_09985	-	-	S	-	-	-	Protein of unknown function (DUF1232)
MACFILCD_02206	3.37e-193	-	-	-	S	ko:K07051	-	ko00000	TatD related DNase
MACFILCD_02207	8.94e-56	-	-	-	-	-	-	-	-
MACFILCD_02208	4.83e-163	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	-
MACFILCD_02209	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
MACFILCD_02210	1.29e-187	-	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	2Fe-2S iron-sulfur cluster binding domain
MACFILCD_02212	7.1e-104	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
MACFILCD_02217	1.89e-80	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
MACFILCD_02219	1.95e-239	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
MACFILCD_02220	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
MACFILCD_02221	0.0	-	-	-	M	-	-	-	pathogenesis
MACFILCD_02223	1.07e-264	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
MACFILCD_02229	2.66e-148	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MACFILCD_02232	0.0	-	-	-	P	-	-	-	Cation transport protein
MACFILCD_02233	6.81e-298	-	-	-	V	ko:K03327	-	ko00000,ko02000	drug transmembrane transporter activity
MACFILCD_02234	1.11e-121	-	-	-	-	-	-	-	-
MACFILCD_02235	9.86e-54	-	-	-	-	-	-	-	-
MACFILCD_02236	8.42e-102	-	-	-	-	-	-	-	-
MACFILCD_02237	0.0	-	2.1.1.182	-	IJ	ko:K02528	-	ko00000,ko01000,ko03009	Ribosomal RNA adenine dimethylases
MACFILCD_02238	1.26e-247	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
MACFILCD_02240	2.05e-28	-	-	-	-	-	-	-	-
MACFILCD_02241	8.07e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	tRNA (Guanine-1)-methyltransferase
MACFILCD_02242	1.03e-237	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MACFILCD_02243	1.66e-87	-	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
MACFILCD_02244	0.0	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
MACFILCD_02246	3.48e-134	-	-	-	C	-	-	-	Nitroreductase family
MACFILCD_02247	1.44e-109	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
MACFILCD_02252	7.29e-211	-	-	-	M	-	-	-	Peptidase family M23
MACFILCD_02253	1.96e-226	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
MACFILCD_02254	4.13e-183	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MACFILCD_02255	4.21e-121	-	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MACFILCD_02256	4.14e-175	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate reductase, N-terminus
MACFILCD_02257	1.25e-204	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
MACFILCD_02260	3.92e-115	-	-	-	-	-	-	-	-
MACFILCD_02261	1.23e-179	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MACFILCD_02263	5.46e-161	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MACFILCD_02264	2.04e-258	tdh	1.1.1.103	-	E	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
MACFILCD_02265	0.0	-	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Carbohydrate phosphorylase
MACFILCD_02266	8.34e-180	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
MACFILCD_02267	1.55e-83	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	ArsC family
MACFILCD_02268	0.0	-	-	-	J	ko:K07576	-	ko00000	Beta-Casp domain
MACFILCD_02269	1.21e-55	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MACFILCD_02270	2.37e-237	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
MACFILCD_02271	2.9e-254	-	-	-	S	-	-	-	Putative S-adenosyl-L-methionine-dependent methyltransferase
MACFILCD_02272	9.74e-227	-	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate synthetase A protein
MACFILCD_02273	7.6e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MACFILCD_02274	0.0	-	3.2.1.52	GH20	G	ko:K01207,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko01501,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map01501,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
MACFILCD_02276	1.53e-107	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
MACFILCD_02278	0.0	-	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate