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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
DEMPHLCK_00001	4.03e-120	-	-	-	-	-	-	-	-
DEMPHLCK_00002	1.51e-198	-	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DEMPHLCK_00003	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
DEMPHLCK_00004	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GcpE protein
DEMPHLCK_00005	5.44e-147	-	-	-	IQ	-	-	-	RmlD substrate binding domain
DEMPHLCK_00006	3.91e-289	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
DEMPHLCK_00007	0.0	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	thiolester hydrolase activity
DEMPHLCK_00008	2.33e-281	-	-	-	IQ	-	-	-	Beta-ketoacyl synthase, C-terminal domain
DEMPHLCK_00009	6.65e-261	-	2.3.1.47	-	H	ko:K00652	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
DEMPHLCK_00013	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DEMPHLCK_00014	7.37e-311	-	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
DEMPHLCK_00015	1.44e-175	hypB	-	-	KO	ko:K04652	-	ko00000,ko03110	CobW/HypB/UreG, nucleotide-binding domain
DEMPHLCK_00016	0.0	-	-	-	O	ko:K04656	-	ko00000	HypF finger
DEMPHLCK_00017	2.74e-50	-	-	-	O	ko:K04653	-	ko00000	HupF/HypC family
DEMPHLCK_00018	1.11e-261	-	-	-	O	ko:K04654	-	ko00000	Hydrogenase formation hypA family
DEMPHLCK_00019	5.1e-241	-	-	-	O	ko:K04655	-	ko00000	AIR synthase related protein, N-terminal domain
DEMPHLCK_00020	1.14e-279	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
DEMPHLCK_00021	0.0	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
DEMPHLCK_00022	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	MreB/Mbl protein
DEMPHLCK_00023	2.2e-61	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DEMPHLCK_00024	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DEMPHLCK_00025	5.31e-99	-	-	-	S	-	-	-	peptidase
DEMPHLCK_00026	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
DEMPHLCK_00030	8.04e-298	-	-	-	-	-	-	-	-
DEMPHLCK_00031	0.0	-	-	-	D	-	-	-	Chain length determinant protein
DEMPHLCK_00032	9.65e-133	-	-	-	M	-	-	-	Polysaccharide biosynthesis/export protein
DEMPHLCK_00034	4.46e-148	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DEMPHLCK_00035	1.67e-249	-	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
DEMPHLCK_00036	3.33e-285	pgk	2.7.2.3	-	G	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
DEMPHLCK_00037	3.67e-236	-	-	-	-	-	-	-	-
DEMPHLCK_00038	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	myo-inosose-2 dehydratase activity
DEMPHLCK_00039	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
DEMPHLCK_00040	0.0	-	-	-	L	-	-	-	TRCF
DEMPHLCK_00041	2.29e-296	-	-	-	-	-	-	-	-
DEMPHLCK_00042	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
DEMPHLCK_00043	3e-254	-	-	-	S	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
DEMPHLCK_00045	5.56e-214	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	PHP domain
DEMPHLCK_00046	1.4e-259	-	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphate acetyl/butaryl transferase
DEMPHLCK_00047	1.16e-241	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DEMPHLCK_00048	2.59e-75	-	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
DEMPHLCK_00052	1.33e-100	-	-	-	MP	-	-	-	regulation of cell-substrate adhesion
DEMPHLCK_00056	0.0	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
DEMPHLCK_00057	1.83e-231	-	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
DEMPHLCK_00058	0.0	-	-	-	G	-	-	-	Glycogen debranching enzyme
DEMPHLCK_00059	0.0	-	-	-	M	-	-	-	NPCBM/NEW2 domain
DEMPHLCK_00060	0.0	-	-	-	M	ko:K04744	-	ko00000,ko02000	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DEMPHLCK_00061	2.94e-155	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
DEMPHLCK_00062	2.51e-191	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
DEMPHLCK_00063	3.05e-169	-	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
DEMPHLCK_00064	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
DEMPHLCK_00065	4.37e-124	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	adenylate kinase activity
DEMPHLCK_00066	8.78e-167	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
DEMPHLCK_00067	0.0	-	-	-	ET	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
DEMPHLCK_00069	2.9e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Semialdehyde dehydrogenase, NAD binding domain
DEMPHLCK_00070	3.21e-306	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DEMPHLCK_00071	1.44e-110	-	-	-	S	-	-	-	Putative zinc- or iron-chelating domain
DEMPHLCK_00072	7.7e-31	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
DEMPHLCK_00074	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	ATPases associated with a variety of cellular activities
DEMPHLCK_00075	4e-147	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
DEMPHLCK_00076	1.14e-126	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
DEMPHLCK_00077	7.06e-249	-	-	-	-	-	-	-	-
DEMPHLCK_00079	4.5e-176	-	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
DEMPHLCK_00080	3.65e-60	-	-	-	S	ko:K09131	-	ko00000	DUF167
DEMPHLCK_00081	1.72e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DEMPHLCK_00082	9.85e-262	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DEMPHLCK_00083	4.47e-174	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DEMPHLCK_00084	2.96e-242	-	3.1.3.18	-	F	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
DEMPHLCK_00085	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
DEMPHLCK_00086	2.91e-228	-	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
DEMPHLCK_00087	0.0	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Peptidase S24-like
DEMPHLCK_00088	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
DEMPHLCK_00089	6.29e-151	-	-	-	-	-	-	-	-
DEMPHLCK_00090	5.95e-167	pks6	-	-	Q	-	-	-	amino acid activation for nonribosomal peptide biosynthetic process
DEMPHLCK_00091	1.06e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF3485)
DEMPHLCK_00092	1.19e-229	-	-	-	C	-	-	-	Transmembrane exosortase (Exosortase_EpsH)
DEMPHLCK_00093	4.58e-220	prs	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEMPHLCK_00094	5.05e-131	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DEMPHLCK_00096	1.48e-141	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
DEMPHLCK_00097	1.31e-147	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DEMPHLCK_00098	1.56e-60	-	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S6
DEMPHLCK_00099	2.97e-210	-	1.1.1.262	-	H	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal phosphate biosynthetic protein PdxA
DEMPHLCK_00102	3.37e-224	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
DEMPHLCK_00103	2.21e-254	-	2.7.1.11, 2.7.1.90	-	G	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Phosphofructokinase
DEMPHLCK_00104	2.58e-256	-	-	-	L	-	-	-	Membrane
DEMPHLCK_00105	6.18e-173	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	transporter
DEMPHLCK_00106	2.92e-233	-	-	-	CO	-	-	-	Protein of unknown function, DUF255
DEMPHLCK_00109	0.0	-	2.6.1.66	-	E	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
DEMPHLCK_00110	4.1e-193	-	-	-	S	-	-	-	Domain of unknown function (DUF1732)
DEMPHLCK_00111	4.39e-145	-	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
DEMPHLCK_00112	0.0	-	-	-	P	-	-	-	Citrate transporter
DEMPHLCK_00113	3.09e-208	-	-	-	J	ko:K01894	-	ko00000,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), catalytic domain
DEMPHLCK_00116	3.1e-217	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
DEMPHLCK_00117	5.46e-170	-	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
DEMPHLCK_00119	1.12e-217	-	-	-	-	-	-	-	-
DEMPHLCK_00120	3.17e-166	-	-	-	S	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
DEMPHLCK_00121	9.03e-173	-	-	-	T	-	-	-	Outer membrane lipoprotein-sorting protein
DEMPHLCK_00122	1.96e-226	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
DEMPHLCK_00123	0.0	secD	-	-	U	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DEMPHLCK_00125	1.62e-278	-	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
DEMPHLCK_00126	2.38e-258	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
DEMPHLCK_00127	2.95e-262	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEMPHLCK_00128	4.19e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
DEMPHLCK_00129	1.54e-217	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Acyl transferase domain
DEMPHLCK_00131	1.63e-169	-	-	-	S	-	-	-	HAD-hyrolase-like
DEMPHLCK_00132	3.06e-286	-	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
DEMPHLCK_00133	1.21e-268	-	-	-	E	-	-	-	serine-type peptidase activity
DEMPHLCK_00134	3.2e-305	-	-	-	M	-	-	-	OmpA family
DEMPHLCK_00135	1.8e-215	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
DEMPHLCK_00136	0.0	-	-	-	M	-	-	-	Peptidase M60-like family
DEMPHLCK_00137	2.8e-295	-	-	-	EGP	-	-	-	Major facilitator Superfamily
DEMPHLCK_00138	0.0	-	-	-	KT	-	-	-	Sigma factor PP2C-like phosphatases
DEMPHLCK_00139	6.91e-165	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
DEMPHLCK_00140	3.33e-242	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
DEMPHLCK_00142	2.01e-157	-	-	-	NU	ko:K02457,ko:K08084	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	protein transport across the cell outer membrane
DEMPHLCK_00143	1.83e-188	-	-	-	-	-	-	-	-
DEMPHLCK_00144	5.15e-247	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
DEMPHLCK_00145	3.43e-183	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
DEMPHLCK_00146	4.06e-244	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
DEMPHLCK_00147	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
DEMPHLCK_00151	0.0	-	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
DEMPHLCK_00152	0.0	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DEMPHLCK_00153	9.26e-175	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
DEMPHLCK_00154	1.7e-154	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
DEMPHLCK_00155	2.54e-287	-	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DEMPHLCK_00156	1.29e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DEMPHLCK_00158	0.0	-	-	-	T	-	-	-	pathogenesis
DEMPHLCK_00159	2.25e-91	-	-	-	O	-	-	-	response to oxidative stress
DEMPHLCK_00160	1.6e-293	-	2.3.1.31	-	E	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko01000	alpha/beta hydrolase fold
DEMPHLCK_00161	1.08e-63	-	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
DEMPHLCK_00162	0.0	-	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Glycosyltransferase family 9 (heptosyltransferase)
DEMPHLCK_00163	1.06e-188	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
DEMPHLCK_00164	0.0	-	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
DEMPHLCK_00165	1.15e-188	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
DEMPHLCK_00166	4.49e-187	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
DEMPHLCK_00167	0.0	-	-	-	EG	-	-	-	BNR repeat-like domain
DEMPHLCK_00168	0.0	legA	3.5.1.2	-	G	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	response to abiotic stimulus
DEMPHLCK_00169	1.32e-195	supH	-	-	Q	-	-	-	phosphatase activity
DEMPHLCK_00171	5.49e-85	nuoA	1.6.5.3	-	C	ko:K00330	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEMPHLCK_00172	7.13e-276	-	-	-	G	-	-	-	Major Facilitator Superfamily
DEMPHLCK_00176	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DEMPHLCK_00177	2.91e-38	-	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
DEMPHLCK_00178	5.25e-79	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DEMPHLCK_00184	1.79e-77	-	-	-	M	-	-	-	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DEMPHLCK_00185	6.05e-222	-	-	-	L	-	-	-	Transposase zinc-ribbon domain
DEMPHLCK_00186	0.0	-	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Peptidase family M50
DEMPHLCK_00189	0.0	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
DEMPHLCK_00190	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
DEMPHLCK_00191	3.07e-211	MA20_36650	-	-	EG	-	-	-	spore germination
DEMPHLCK_00192	3.57e-190	dpnC	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Dam-replacing family
DEMPHLCK_00193	0.0	-	-	-	S	-	-	-	Alpha-2-macroglobulin family
DEMPHLCK_00194	1.94e-289	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
DEMPHLCK_00196	2.89e-123	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
DEMPHLCK_00199	1.79e-213	-	-	-	-	-	-	-	-
DEMPHLCK_00200	3.97e-152	-	-	-	O	-	-	-	Glycoprotease family
DEMPHLCK_00201	4.28e-274	-	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
DEMPHLCK_00203	3.86e-112	-	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DEMPHLCK_00204	4.12e-139	-	-	-	L	-	-	-	RNase_H superfamily
DEMPHLCK_00205	1.92e-102	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DEMPHLCK_00206	4.3e-44	-	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	RNA polymerase activity
DEMPHLCK_00207	1.34e-135	-	5.4.99.20	-	J	ko:K06181	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
DEMPHLCK_00208	2.16e-188	-	-	-	-	-	-	-	-
DEMPHLCK_00209	1.3e-104	-	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	NDK
DEMPHLCK_00210	1.71e-201	-	-	-	S	-	-	-	Glycosyltransferase like family 2
DEMPHLCK_00211	4.12e-225	-	-	-	M	-	-	-	Glycosyl transferase family 2
DEMPHLCK_00212	1.34e-07	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
DEMPHLCK_00213	7.26e-285	-	-	-	NU	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
DEMPHLCK_00214	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein E, N-terminal domain
DEMPHLCK_00215	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
DEMPHLCK_00216	4.22e-244	-	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DEMPHLCK_00217	2.83e-110	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
DEMPHLCK_00218	3.86e-281	-	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
DEMPHLCK_00219	0.0	murJ	-	-	S	ko:K03980	-	ko00000,ko01011,ko02000	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
DEMPHLCK_00220	1.21e-269	-	-	-	IM	-	-	-	Cytidylyltransferase-like
DEMPHLCK_00221	2.89e-156	-	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Iron/manganese superoxide dismutases, alpha-hairpin domain
DEMPHLCK_00222	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase-like 10
DEMPHLCK_00223	4.2e-171	-	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
DEMPHLCK_00224	1.39e-190	-	-	-	L	ko:K06864	-	ko00000	tRNA processing
DEMPHLCK_00225	3.77e-288	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
DEMPHLCK_00226	1.07e-238	-	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Polyprenyl synthetase
DEMPHLCK_00227	0.0	-	-	-	E	ko:K03305	-	ko00000	POT family
DEMPHLCK_00228	0.0	-	5.2.1.8	-	O	ko:K03770	-	ko00000,ko01000,ko03110	PPIC-type PPIASE domain
DEMPHLCK_00229	2.39e-126	-	-	-	S	-	-	-	Pfam:DUF59
DEMPHLCK_00230	7.43e-107	-	-	-	-	-	-	-	-
DEMPHLCK_00232	8.93e-219	-	-	-	E	-	-	-	Domain of unknown function (DUF3472)
DEMPHLCK_00233	9.04e-317	nuoN	1.6.5.3	-	C	ko:K00343	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEMPHLCK_00234	0.0	-	1.6.5.3	-	C	ko:K00342	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Proton-conducting membrane transporter
DEMPHLCK_00235	0.0	-	1.6.5.3	-	CP	ko:K00341	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
DEMPHLCK_00236	6.01e-61	nuoK	1.6.5.3	-	C	ko:K00340	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEMPHLCK_00237	4.41e-156	-	1.6.5.3	-	C	ko:K00339	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone/plastoquinone oxidoreductase chain 6
DEMPHLCK_00238	1.8e-124	nuoI	1.6.5.3	-	C	ko:K00338	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEMPHLCK_00239	1.04e-309	nuoH	1.6.5.3	-	C	ko:K00337	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DEMPHLCK_00240	0.0	-	1.6.5.3	-	C	ko:K00336	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
DEMPHLCK_00241	0.0	-	1.6.5.3	-	C	ko:K00335	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
DEMPHLCK_00242	2.88e-142	-	1.6.5.3	-	C	ko:K00334	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Thioredoxin-like [2Fe-2S] ferredoxin
DEMPHLCK_00243	4.39e-307	nuoD	1.6.5.3	-	C	ko:K00333	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEMPHLCK_00245	0.0	-	-	-	G	-	-	-	Polysaccharide deacetylase
DEMPHLCK_00246	0.0	-	-	-	P	-	-	-	Putative Na+/H+ antiporter
DEMPHLCK_00247	1.07e-141	-	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Lumazine binding domain
DEMPHLCK_00248	7.24e-205	-	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
DEMPHLCK_00249	0.0	pmp21	-	-	T	-	-	-	pathogenesis
DEMPHLCK_00250	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
DEMPHLCK_00252	0.0	-	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Uncharacterized protein family UPF0004
DEMPHLCK_00253	0.0	-	-	-	-	ko:K07403	-	ko00000	-
DEMPHLCK_00254	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DEMPHLCK_00255	0.0	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DEMPHLCK_00256	3.72e-187	-	3.4.13.22	-	M	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-ala-D-ala dipeptidase
DEMPHLCK_00259	0.0	-	-	-	E	-	-	-	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEMPHLCK_00260	0.0	-	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	tail specific protease
DEMPHLCK_00262	3.14e-213	-	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
DEMPHLCK_00263	0.0	-	3.6.4.13	-	L	ko:K03579	-	ko00000,ko01000	ATP-dependent helicase C-terminal
DEMPHLCK_00264	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
DEMPHLCK_00265	3.39e-311	-	-	-	O	-	-	-	peroxiredoxin activity
DEMPHLCK_00266	0.0	-	2.7.7.19	-	J	ko:K00970	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Poly A polymerase head domain
DEMPHLCK_00267	0.0	-	-	-	G	-	-	-	Alpha amylase, catalytic domain
DEMPHLCK_00268	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
DEMPHLCK_00269	0.0	-	-	-	-	-	-	-	-
DEMPHLCK_00270	7.21e-183	-	-	-	S	ko:K09778	-	ko00000	Domain of unknown function (DUF374)
DEMPHLCK_00271	7.21e-203	folD	1.5.1.5, 3.5.4.9	-	H	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DEMPHLCK_00272	2.91e-182	-	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
DEMPHLCK_00273	2.62e-202	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
DEMPHLCK_00274	4.88e-284	-	-	-	E	-	-	-	Transglutaminase-like superfamily
DEMPHLCK_00275	8.69e-261	-	-	-	J	ko:K05541	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DEMPHLCK_00276	1.31e-289	-	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	LytB protein
DEMPHLCK_00278	2.34e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S20
DEMPHLCK_00279	3.88e-140	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
DEMPHLCK_00280	0.0	-	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
DEMPHLCK_00281	1.27e-220	-	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Phosphatidylserine decarboxylase
DEMPHLCK_00282	1.1e-151	-	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3 epimerase family
DEMPHLCK_00283	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Leucyl-tRNA synthetase, Domain 2
DEMPHLCK_00284	0.0	-	-	-	P	-	-	-	Sulfatase
DEMPHLCK_00286	7.45e-301	-	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
DEMPHLCK_00287	0.0	-	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
DEMPHLCK_00288	3.33e-268	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DEMPHLCK_00289	7.15e-184	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
DEMPHLCK_00290	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
DEMPHLCK_00291	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
DEMPHLCK_00292	0.0	rarA	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
DEMPHLCK_00293	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
DEMPHLCK_00295	3.87e-301	-	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
DEMPHLCK_00296	7.83e-98	-	-	-	M	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
DEMPHLCK_00297	1.26e-71	-	-	-	M	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
DEMPHLCK_00298	3.61e-268	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
DEMPHLCK_00302	8.79e-263	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DEMPHLCK_00303	0.0	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Type III restriction enzyme res subunit
DEMPHLCK_00304	0.0	-	-	-	L	-	-	-	Type III restriction enzyme res subunit
DEMPHLCK_00305	1.82e-126	cobU	2.7.1.156, 2.7.7.62, 6.3.5.10	-	H	ko:K02231,ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cobinamide kinase activity
DEMPHLCK_00306	6.74e-207	-	-	-	G	-	-	-	myo-inosose-2 dehydratase activity
DEMPHLCK_00307	6.59e-172	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DEMPHLCK_00308	4.02e-239	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DEMPHLCK_00309	9.28e-227	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DEMPHLCK_00310	0.0	cobQ	-	-	H	-	-	-	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
DEMPHLCK_00312	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
DEMPHLCK_00314	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
DEMPHLCK_00315	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
DEMPHLCK_00316	3.85e-159	-	-	-	M	ko:K16079	-	ko00000,ko02000	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DEMPHLCK_00317	2.34e-312	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
DEMPHLCK_00318	0.0	-	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
DEMPHLCK_00319	5.53e-96	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
DEMPHLCK_00320	8.04e-60	-	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	nucleotidyltransferase activity
DEMPHLCK_00321	1.47e-229	-	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
DEMPHLCK_00322	0.0	-	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoglutarate dehydrogenase C-terminal
DEMPHLCK_00323	1.48e-245	-	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit II
DEMPHLCK_00324	0.0	-	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
DEMPHLCK_00325	2.7e-113	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
DEMPHLCK_00326	2.34e-107	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
DEMPHLCK_00327	0.0	-	-	-	T	-	-	-	Chase2 domain
DEMPHLCK_00328	9.8e-232	-	2.7.1.221	-	S	ko:K07102	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Phosphotransferase enzyme family
DEMPHLCK_00329	1.25e-307	-	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DEMPHLCK_00330	4.98e-92	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
DEMPHLCK_00332	3.01e-113	-	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Ferritin-like domain
DEMPHLCK_00333	0.0	-	-	-	-	-	-	-	-
DEMPHLCK_00334	3.15e-103	-	-	-	J	-	-	-	YjgF/chorismate_mutase-like, putative endoribonuclease
DEMPHLCK_00336	7.16e-115	-	-	-	S	ko:K03748	-	ko00000	DUF218 domain
DEMPHLCK_00338	2.29e-229	-	-	-	S	-	-	-	mannose-ethanolamine phosphotransferase activity
DEMPHLCK_00342	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RQC
DEMPHLCK_00344	2.23e-176	-	-	-	-	-	-	-	-
DEMPHLCK_00345	3.89e-209	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DEMPHLCK_00346	2.18e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
DEMPHLCK_00347	6.3e-291	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DEMPHLCK_00348	2.23e-205	-	-	-	S	ko:K03453	-	ko00000	Bile acid
DEMPHLCK_00351	6.39e-71	-	-	-	-	-	-	-	-
DEMPHLCK_00352	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DEMPHLCK_00353	0.0	-	2.3.1.40, 6.2.1.20	-	IQ	ko:K05939	ko00071,ko00564,map00071,map00564	ko00000,ko00001,ko01000	AMP-binding enzyme
DEMPHLCK_00354	2.01e-48	-	-	-	T	-	-	-	pathogenesis
DEMPHLCK_00357	2.3e-229	-	-	-	S	-	-	-	Protein of unknown function (DUF1194)
DEMPHLCK_00358	8.06e-134	-	-	-	-	-	-	-	-
DEMPHLCK_00359	1.26e-210	-	-	-	S	-	-	-	Protein of unknown function DUF58
DEMPHLCK_00360	2.48e-228	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
DEMPHLCK_00361	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DEMPHLCK_00362	8.23e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEMPHLCK_00364	2.63e-10	-	-	-	-	-	-	-	-
DEMPHLCK_00367	2.74e-284	-	-	-	S	-	-	-	Tetratricopeptide repeat
DEMPHLCK_00368	0.0	-	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
DEMPHLCK_00369	6.2e-203	-	-	-	-	-	-	-	-
DEMPHLCK_00370	3.31e-239	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
DEMPHLCK_00371	3.4e-178	-	-	-	O	-	-	-	Trypsin
DEMPHLCK_00377	4.71e-33	-	-	-	M	-	-	-	lytic transglycosylase activity
DEMPHLCK_00378	4.93e-64	-	-	-	F	-	-	-	acetyltransferase
DEMPHLCK_00380	1.04e-65	-	-	-	KT	-	-	-	Peptidase S24-like
DEMPHLCK_00392	1.54e-305	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
DEMPHLCK_00398	1.72e-41	-	-	-	-	-	-	-	-
DEMPHLCK_00400	4.25e-160	-	-	-	S	-	-	-	Terminase
DEMPHLCK_00405	1.76e-130	-	-	-	S	-	-	-	Glycosyl hydrolase 108
DEMPHLCK_00407	3.8e-80	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
DEMPHLCK_00411	6.03e-292	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
DEMPHLCK_00412	2.07e-195	-	-	-	KT	-	-	-	Peptidase S24-like
DEMPHLCK_00414	2.66e-140	-	-	-	M	-	-	-	polygalacturonase activity
DEMPHLCK_00415	1.39e-301	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
DEMPHLCK_00416	3.45e-239	-	1.2.7.3	-	-	ko:K00176,ko:K07138	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	-
DEMPHLCK_00417	1.3e-205	-	-	-	S	-	-	-	Aldo/keto reductase family
DEMPHLCK_00418	2.97e-268	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
DEMPHLCK_00419	4.24e-270	-	-	-	C	-	-	-	Aldo/keto reductase family
DEMPHLCK_00420	8.47e-264	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
DEMPHLCK_00421	9.98e-129	-	-	-	C	-	-	-	FMN binding
DEMPHLCK_00422	7.2e-103	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
DEMPHLCK_00423	1.11e-188	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
DEMPHLCK_00424	4.8e-128	-	-	-	S	-	-	-	Flavodoxin-like fold
DEMPHLCK_00425	7.97e-113	-	-	-	K	ko:K13640	-	ko00000,ko03000	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
DEMPHLCK_00426	1.65e-102	-	-	-	G	-	-	-	single-species biofilm formation
DEMPHLCK_00427	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
DEMPHLCK_00428	0.0	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
DEMPHLCK_00430	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
DEMPHLCK_00431	1.11e-239	-	4.2.1.113	-	M	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Mandelate Racemase Muconate Lactonizing
DEMPHLCK_00432	3.06e-216	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
DEMPHLCK_00433	0.0	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	RNA cap guanine-N2 methyltransferase
DEMPHLCK_00434	0.0	-	-	-	-	-	-	-	-
DEMPHLCK_00435	3.87e-56	-	-	-	S	ko:K06960	-	ko00000	KH domain
DEMPHLCK_00436	6.71e-285	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
DEMPHLCK_00437	2.45e-216	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DEMPHLCK_00440	2.05e-173	-	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	FtsJ-like methyltransferase
DEMPHLCK_00442	1.84e-171	-	-	-	S	ko:K06911	-	ko00000	Pirin
DEMPHLCK_00443	0.0	-	-	-	M	-	-	-	AsmA-like C-terminal region
DEMPHLCK_00445	1.03e-201	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
DEMPHLCK_00446	0.0	-	2.7.1.51	-	G	ko:K00879	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
DEMPHLCK_00448	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
DEMPHLCK_00449	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
DEMPHLCK_00450	1.12e-121	-	-	-	-	-	-	-	-
DEMPHLCK_00451	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	N-terminal domain of BNR-repeat neuraminidase
DEMPHLCK_00452	2.06e-133	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
DEMPHLCK_00453	7.29e-60	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
DEMPHLCK_00454	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
DEMPHLCK_00455	0.0	-	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	ThiC-associated domain
DEMPHLCK_00456	2.19e-220	ytpP	2.7.1.180, 5.3.4.1	-	CO	ko:K01829,ko:K03671,ko:K03734,ko:K06196	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko02000,ko03110	cell redox homeostasis
DEMPHLCK_00457	1.3e-139	-	-	-	K	-	-	-	ECF sigma factor
DEMPHLCK_00459	4.78e-222	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
DEMPHLCK_00460	3.06e-232	-	-	-	O	-	-	-	Parallel beta-helix repeats
DEMPHLCK_00461	0.0	-	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
DEMPHLCK_00462	1.95e-284	-	-	-	Q	-	-	-	Multicopper oxidase
DEMPHLCK_00463	1.16e-209	-	-	-	EG	-	-	-	EamA-like transporter family
DEMPHLCK_00465	2.2e-274	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DEMPHLCK_00466	6.48e-244	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
DEMPHLCK_00467	9.42e-232	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
DEMPHLCK_00468	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
DEMPHLCK_00469	0.0	-	-	-	P	ko:K13895	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DEMPHLCK_00470	0.0	-	-	-	EP	ko:K13894	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DEMPHLCK_00471	1.4e-185	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
DEMPHLCK_00472	1.35e-207	-	-	-	S	-	-	-	Tetratricopeptide repeat
DEMPHLCK_00473	9.98e-223	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase PanE/ApbA C terminal
DEMPHLCK_00474	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate--tetrahydrofolate ligase
DEMPHLCK_00475	5.77e-145	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
DEMPHLCK_00476	8.95e-316	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
DEMPHLCK_00477	3.77e-118	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
DEMPHLCK_00478	2.52e-281	-	5.4.99.22	-	M	ko:K06178	-	ko00000,ko01000,ko03009	translation initiation factor activity
DEMPHLCK_00479	1.27e-133	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
DEMPHLCK_00480	7.4e-93	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
DEMPHLCK_00481	8.02e-130	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DEMPHLCK_00482	8.59e-293	-	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 57
DEMPHLCK_00483	1.25e-315	-	-	-	G	-	-	-	Glycosyl transferase 4-like domain
DEMPHLCK_00484	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 31
DEMPHLCK_00485	6.05e-250	-	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	chorismate binding enzyme
DEMPHLCK_00486	3.89e-313	-	-	-	C	ko:K00185	-	ko00000	Polysulphide reductase, NrfD
DEMPHLCK_00488	7.47e-156	-	-	-	C	-	-	-	Cytochrome c
DEMPHLCK_00489	4.3e-296	-	-	-	P	-	-	-	ABC-type Zn2 transport system, periplasmic component surface adhesin
DEMPHLCK_00490	0.0	-	-	-	C	-	-	-	Cytochrome c
DEMPHLCK_00492	1.38e-60	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DEMPHLCK_00493	1.13e-270	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
DEMPHLCK_00494	6.74e-307	-	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
DEMPHLCK_00495	1.05e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
DEMPHLCK_00496	2.48e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
DEMPHLCK_00497	0.0	-	-	-	J	-	-	-	Beta-Casp domain
DEMPHLCK_00498	4.02e-144	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DEMPHLCK_00499	1.02e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Queuosine biosynthesis protein QueC
DEMPHLCK_00500	1.78e-97	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	QueF-like protein
DEMPHLCK_00501	0.0	kefA	-	-	M	ko:K05802,ko:K22051	-	ko00000,ko02000	cellular water homeostasis
DEMPHLCK_00502	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DEMPHLCK_00503	7.46e-238	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEMPHLCK_00504	1.44e-191	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin resistance protein BacA
DEMPHLCK_00507	1.05e-84	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
DEMPHLCK_00508	4.68e-315	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DEMPHLCK_00509	1.65e-303	-	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
DEMPHLCK_00510	1.33e-52	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DEMPHLCK_00511	4.17e-260	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DEMPHLCK_00513	8.29e-100	cysJ	1.8.1.2	-	C	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	hydroxylamine reductase activity
DEMPHLCK_00515	5.74e-200	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
DEMPHLCK_00516	1.06e-169	BT0174	-	-	C	ko:K04488	-	ko00000	iron-sulfur transferase activity
DEMPHLCK_00517	2.08e-240	BT0173	-	-	S	-	-	-	Psort location Cytoplasmic, score
DEMPHLCK_00519	7.78e-269	-	2.1.1.72	-	H	ko:K07318	-	ko00000,ko01000,ko02048	PFAM D12 class N6 adenine-specific DNA methyltransferase
DEMPHLCK_00520	6.72e-210	-	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
DEMPHLCK_00525	3.48e-274	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
DEMPHLCK_00526	6.02e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DEMPHLCK_00527	2.49e-229	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
DEMPHLCK_00528	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
DEMPHLCK_00529	4.66e-230	-	2.7.7.13	-	JM	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
DEMPHLCK_00530	4.47e-176	-	-	-	S	-	-	-	Phosphodiester glycosidase
DEMPHLCK_00531	0.0	-	-	GT2	M	ko:K03820	-	ko00000,ko01000	Carbon-nitrogen hydrolase
DEMPHLCK_00532	1.33e-51	-	-	-	C	-	-	-	4Fe-4S single cluster domain of Ferredoxin I
DEMPHLCK_00533	1.12e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
DEMPHLCK_00534	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
DEMPHLCK_00535	2.52e-237	-	-	-	S	-	-	-	Acyltransferase family
DEMPHLCK_00536	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
DEMPHLCK_00537	2.69e-185	ccs1	-	-	O	ko:K07399	-	ko00000	cytochrome c biogenesis protein
DEMPHLCK_00538	2.42e-209	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion transport
DEMPHLCK_00539	1.06e-180	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
DEMPHLCK_00540	1.23e-228	fatC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
DEMPHLCK_00541	4.39e-219	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
DEMPHLCK_00542	2.43e-264	-	-	-	J	-	-	-	Endoribonuclease L-PSP
DEMPHLCK_00543	0.0	-	-	-	C	-	-	-	Di-haem oxidoreductase, putative peroxidase
DEMPHLCK_00544	7.56e-246	-	-	-	S	-	-	-	Imelysin
DEMPHLCK_00545	6.48e-142	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
DEMPHLCK_00547	1.82e-125	-	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Phosphoribosyl transferase domain
DEMPHLCK_00548	0.0	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	Helix-hairpin-helix class 2 (Pol1 family) motifs
DEMPHLCK_00549	1.37e-249	-	-	-	M	-	-	-	HlyD family secretion protein
DEMPHLCK_00550	1.78e-102	MA20_05485	-	-	S	-	-	-	Putative bacterial sensory transduction regulator
DEMPHLCK_00551	0.0	-	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
DEMPHLCK_00552	1.46e-302	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
DEMPHLCK_00553	0.0	-	-	-	D	-	-	-	Tetratricopeptide repeat
DEMPHLCK_00554	1.47e-193	-	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
DEMPHLCK_00555	0.0	-	-	-	-	-	-	-	-
DEMPHLCK_00556	6.55e-222	-	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
DEMPHLCK_00557	6.68e-314	-	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
DEMPHLCK_00558	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
DEMPHLCK_00559	5.32e-148	-	4.1.3.38	-	E	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	branched-chain-amino-acid transaminase activity
DEMPHLCK_00560	1.04e-246	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DEMPHLCK_00561	2.09e-150	-	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
DEMPHLCK_00562	4.49e-269	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
DEMPHLCK_00563	2.5e-170	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
DEMPHLCK_00564	2.11e-118	-	-	-	T	ko:K07005	-	ko00000	pyridoxamine 5'-phosphate
DEMPHLCK_00565	7.17e-172	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Glutamine amidotransferase class-I
DEMPHLCK_00567	2.87e-112	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Cys-tRNA(Pro) hydrolase activity
DEMPHLCK_00568	0.0	mmyX	5.3.1.12	-	F	ko:K01812,ko:K07149,ko:K16139	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score
DEMPHLCK_00569	6.74e-106	-	-	-	-	-	-	-	-
DEMPHLCK_00572	4.37e-147	-	-	-	Q	-	-	-	PA14
DEMPHLCK_00573	0.0	-	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	B12 binding domain
DEMPHLCK_00574	1.66e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
DEMPHLCK_00575	1.45e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
DEMPHLCK_00576	2.9e-315	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system DNA methylase K03427
DEMPHLCK_00577	1.45e-76	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
DEMPHLCK_00578	4.48e-62	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
DEMPHLCK_00579	6.93e-141	-	-	-	K	-	-	-	Fic/DOC family
DEMPHLCK_00580	1.36e-168	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DEMPHLCK_00581	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
DEMPHLCK_00583	0.0	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
DEMPHLCK_00584	2.52e-281	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
DEMPHLCK_00585	1.12e-116	agmK	1.8.1.8	-	O	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	belongs to the thioredoxin family
DEMPHLCK_00586	2.72e-181	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
DEMPHLCK_00588	0.0	-	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
DEMPHLCK_00589	2.18e-218	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DEMPHLCK_00590	5.88e-259	-	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	endonuclease III
DEMPHLCK_00591	4.25e-144	aat	2.3.2.6	-	O	ko:K00684	-	ko00000,ko01000	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DEMPHLCK_00592	0.0	-	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Pyruvate phosphate dikinase, PEP/pyruvate binding domain
DEMPHLCK_00593	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglucose isomerase
DEMPHLCK_00594	3.86e-261	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
DEMPHLCK_00595	4.45e-225	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
DEMPHLCK_00597	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
DEMPHLCK_00598	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
DEMPHLCK_00599	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
DEMPHLCK_00600	2.94e-131	-	-	-	-	-	-	-	-
DEMPHLCK_00601	2.75e-244	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
DEMPHLCK_00604	8.93e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyrroline-5-carboxylate reductase dimerisation
DEMPHLCK_00605	4.69e-159	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
DEMPHLCK_00606	5.51e-211	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
DEMPHLCK_00607	6.59e-227	-	-	-	S	-	-	-	Protein conserved in bacteria
DEMPHLCK_00608	2.01e-34	-	-	-	KLT	-	-	-	Tyrosine-protein kinase, subgroup, catalytic domain
DEMPHLCK_00609	0.0	-	4.1.99.1	-	E	ko:K01667	ko00380,map00380	ko00000,ko00001,ko01000	Beta-eliminating lyase
DEMPHLCK_00610	6.76e-143	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
DEMPHLCK_00611	1.75e-255	-	-	-	S	-	-	-	Domain of unknown function (DUF4105)
DEMPHLCK_00612	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	B3/4 domain
DEMPHLCK_00613	6.99e-242	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Aminoacyl tRNA synthetase class II, N-terminal domain
DEMPHLCK_00614	1.11e-283	-	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
DEMPHLCK_00615	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
DEMPHLCK_00616	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Hsp90 protein
DEMPHLCK_00617	6.67e-172	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
DEMPHLCK_00618	1.95e-273	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DEMPHLCK_00619	9.25e-103	-	-	-	K	-	-	-	Transcriptional regulator
DEMPHLCK_00620	8.64e-312	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
DEMPHLCK_00621	9.2e-215	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
DEMPHLCK_00622	8.4e-136	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K00788,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
DEMPHLCK_00623	1.15e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DEMPHLCK_00624	4.27e-117	gepA	-	-	K	-	-	-	Phage-associated protein
DEMPHLCK_00626	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
DEMPHLCK_00627	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
DEMPHLCK_00628	1.21e-241	-	-	-	E	ko:K07588	-	ko00000,ko01000	ArgK protein
DEMPHLCK_00629	1.82e-112	-	-	-	F	ko:K08311	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	NUDIX domain
DEMPHLCK_00630	0.0	sepA	-	-	Q	-	-	-	COG2015, Alkyl sulfatase and related hydrolases
DEMPHLCK_00631	4.02e-121	-	-	-	-	-	-	-	-
DEMPHLCK_00632	1.71e-110	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DEMPHLCK_00633	1.48e-291	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
DEMPHLCK_00634	1.16e-158	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
DEMPHLCK_00635	8.82e-241	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase
DEMPHLCK_00637	1.69e-107	-	-	-	K	-	-	-	DNA-binding transcription factor activity
DEMPHLCK_00638	4.2e-264	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Biotin-lipoyl like
DEMPHLCK_00639	0.0	-	-	-	V	-	-	-	AcrB/AcrD/AcrF family
DEMPHLCK_00640	8.33e-114	-	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Dihydrofolate reductase
DEMPHLCK_00641	5.77e-208	-	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Thymidylate synthase
DEMPHLCK_00642	0.0	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phospholipase D. Active site motifs.
DEMPHLCK_00643	0.0	-	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	HMGL-like
DEMPHLCK_00645	0.0	-	-	-	V	ko:K03327	-	ko00000,ko02000	MatE
DEMPHLCK_00646	1.23e-255	-	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Iron-sulfur cluster assembly protein
DEMPHLCK_00647	6.78e-42	-	-	-	S	-	-	-	PurA ssDNA and RNA-binding protein
DEMPHLCK_00649	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	LeuA allosteric (dimerisation) domain
DEMPHLCK_00650	0.0	prlC	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
DEMPHLCK_00651	1.58e-282	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEMPHLCK_00652	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DEMPHLCK_00653	0.0	-	-	-	MU	ko:K18139	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Outer membrane efflux protein
DEMPHLCK_00655	0.0	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
DEMPHLCK_00656	1.85e-149	-	-	-	-	-	-	-	-
DEMPHLCK_00659	1.34e-109	ptsN	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
DEMPHLCK_00660	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
DEMPHLCK_00661	2.47e-253	-	-	-	L	-	-	-	Transposase IS200 like
DEMPHLCK_00662	0.0	-	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
DEMPHLCK_00663	7.89e-268	-	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DEMPHLCK_00664	1.58e-148	dedA	-	-	S	-	-	-	FtsZ-dependent cytokinesis
DEMPHLCK_00665	1.3e-116	-	-	-	S	-	-	-	nitrogen fixation
DEMPHLCK_00666	6.22e-74	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DEMPHLCK_00667	6.11e-76	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
DEMPHLCK_00668	1.26e-112	-	-	-	CO	-	-	-	cell redox homeostasis
DEMPHLCK_00670	1.5e-180	-	-	-	-	-	-	-	-
DEMPHLCK_00672	0.0	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
DEMPHLCK_00674	2.33e-143	-	-	-	-	-	-	-	-
DEMPHLCK_00675	6.96e-64	-	-	-	K	-	-	-	DNA-binding transcription factor activity
DEMPHLCK_00694	5.39e-39	-	-	-	L	-	-	-	Mu-like prophage protein gp29
DEMPHLCK_00696	5.39e-136	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
DEMPHLCK_00697	8.36e-174	-	-	-	S	-	-	-	peptidoglycan biosynthetic process
DEMPHLCK_00698	6.18e-205	-	1.4.1.16	-	S	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
DEMPHLCK_00700	0.000103	-	-	-	S	-	-	-	Entericidin EcnA/B family
DEMPHLCK_00701	1.99e-233	-	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	prohibitin homologues
DEMPHLCK_00702	2.13e-118	-	-	-	-	-	-	-	-
DEMPHLCK_00703	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
DEMPHLCK_00704	2.22e-298	lpxK	2.7.1.130	-	M	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
DEMPHLCK_00705	1.94e-140	-	-	-	S	ko:K07164	-	ko00000	C4-type zinc ribbon domain
DEMPHLCK_00706	2.24e-264	-	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
DEMPHLCK_00707	3.03e-74	-	-	-	-	-	-	-	-
DEMPHLCK_00708	1.97e-189	-	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	MazG nucleotide pyrophosphohydrolase domain
DEMPHLCK_00709	2.92e-70	-	-	-	-	-	-	-	-
DEMPHLCK_00710	2.51e-182	-	-	-	S	-	-	-	competence protein
DEMPHLCK_00711	6.79e-100	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
DEMPHLCK_00714	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Sulfatase
DEMPHLCK_00715	2.63e-143	-	-	-	-	-	-	-	-
DEMPHLCK_00716	1.06e-163	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
DEMPHLCK_00717	4.82e-178	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DEMPHLCK_00718	2.6e-298	-	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	16S rRNA methyltransferase RsmB/F
DEMPHLCK_00719	9.36e-114	-	3.1.6.8	-	P	ko:K01134	ko00600,ko04142,map00600,map04142	ko00000,ko00001,ko01000	COG3119 Arylsulfatase A
DEMPHLCK_00720	2.9e-316	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Arginosuccinate synthase
DEMPHLCK_00722	2.79e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEMPHLCK_00723	8.43e-59	-	-	-	S	-	-	-	Zinc ribbon domain
DEMPHLCK_00724	4.77e-310	-	-	-	S	-	-	-	PFAM CBS domain containing protein
DEMPHLCK_00725	2.51e-151	-	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
DEMPHLCK_00726	4.83e-82	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
DEMPHLCK_00728	1.67e-177	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
DEMPHLCK_00729	3.4e-229	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
DEMPHLCK_00730	2.14e-148	-	-	-	S	-	-	-	3D domain
DEMPHLCK_00731	2.15e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DEMPHLCK_00732	9.91e-171	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
DEMPHLCK_00733	1.65e-113	aglS	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
DEMPHLCK_00734	4.52e-101	exbD2	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
DEMPHLCK_00736	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
DEMPHLCK_00737	5.47e-195	-	-	-	-	-	-	-	-
DEMPHLCK_00738	8.99e-277	-	-	-	K	-	-	-	sequence-specific DNA binding
DEMPHLCK_00739	0.0	-	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	Ribonuclease E/G family
DEMPHLCK_00740	5.06e-236	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Actin
DEMPHLCK_00741	0.0	lacZ_17	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
DEMPHLCK_00743	2.24e-263	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
DEMPHLCK_00745	7.5e-177	-	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
DEMPHLCK_00746	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
DEMPHLCK_00747	2.26e-115	-	-	-	-	-	-	-	-
DEMPHLCK_00748	1.89e-166	-	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	SAICAR synthetase
DEMPHLCK_00749	0.0	-	-	-	K	-	-	-	Transcription elongation factor, N-terminal
DEMPHLCK_00750	0.0	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DEMPHLCK_00751	1.05e-180	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DEMPHLCK_00752	6.75e-305	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DEMPHLCK_00753	1.34e-201	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase, N-terminal
DEMPHLCK_00754	1.06e-109	-	-	-	S	ko:K15977	-	ko00000	DoxX
DEMPHLCK_00755	2.76e-292	-	4.2.1.129, 5.4.99.17	-	I	ko:K06045	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
DEMPHLCK_00756	4.7e-193	-	-	-	-	-	-	-	-
DEMPHLCK_00757	1.18e-224	-	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
DEMPHLCK_00758	9.39e-183	-	-	-	H	-	-	-	ThiF family
DEMPHLCK_00759	3.67e-126	-	-	-	U	-	-	-	response to pH
DEMPHLCK_00760	2.89e-223	-	-	-	-	-	-	-	-
DEMPHLCK_00761	4.09e-218	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DEMPHLCK_00763	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
DEMPHLCK_00764	3.11e-271	-	-	-	S	-	-	-	COGs COG4299 conserved
DEMPHLCK_00765	5.1e-153	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
DEMPHLCK_00766	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein dimerisation domain
DEMPHLCK_00767	0.0	-	-	-	-	-	-	-	-
DEMPHLCK_00768	6.27e-219	-	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	ATP synthase A chain
DEMPHLCK_00769	1.65e-11	-	-	-	S	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	PFAM H transporting two-sector ATPase C subunit
DEMPHLCK_00770	4.38e-78	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase B/B' CF(0)
DEMPHLCK_00771	6.46e-86	-	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase delta (OSCP) subunit
DEMPHLCK_00772	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DEMPHLCK_00773	4.5e-201	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DEMPHLCK_00774	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DEMPHLCK_00775	1.24e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
DEMPHLCK_00776	1.38e-139	-	-	-	-	-	-	-	-
DEMPHLCK_00777	8.17e-124	sprT	-	-	K	-	-	-	SprT-like family
DEMPHLCK_00778	4.27e-275	-	-	-	S	-	-	-	COGs COG4299 conserved
DEMPHLCK_00779	7.67e-285	-	2.6.1.59	-	M	ko:K02805	-	ko00000,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
DEMPHLCK_00780	4.94e-114	flmH	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEMPHLCK_00781	7.63e-220	-	-	-	M	-	-	-	Glycosyl transferase family 2
DEMPHLCK_00782	1.08e-73	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
DEMPHLCK_00783	1.85e-75	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
DEMPHLCK_00786	0.0	-	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
DEMPHLCK_00787	2.93e-233	-	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Biotin and Thiamin Synthesis associated domain
DEMPHLCK_00788	0.0	-	-	-	P	-	-	-	Sulfatase
DEMPHLCK_00789	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
DEMPHLCK_00790	2.6e-296	-	-	-	O	ko:K09015	-	ko00000	Uncharacterized protein family (UPF0051)
DEMPHLCK_00791	0.0	-	-	-	O	ko:K09014	-	ko00000	Uncharacterized protein family (UPF0051)
DEMPHLCK_00792	8.34e-178	-	-	-	O	ko:K09013	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
DEMPHLCK_00793	6.78e-100	-	-	-	P	ko:K09825	-	ko00000,ko03000	Ferric uptake regulator family
DEMPHLCK_00794	2.14e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
DEMPHLCK_00795	1.93e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal prokaryotic L21 protein
DEMPHLCK_00796	1.65e-106	-	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
DEMPHLCK_00797	1.07e-199	-	-	-	S	ko:K06889	-	ko00000	alpha beta
DEMPHLCK_00799	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
DEMPHLCK_00800	0.0	-	-	-	-	-	-	-	-
DEMPHLCK_00801	2.58e-225	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
DEMPHLCK_00803	1.36e-175	-	-	-	-	-	-	-	-
DEMPHLCK_00804	3.35e-131	-	-	-	L	-	-	-	Conserved hypothetical protein 95
DEMPHLCK_00805	1.18e-309	-	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
DEMPHLCK_00806	9.68e-226	-	-	-	S	-	-	-	Aspartyl protease
DEMPHLCK_00807	1.67e-272	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DEMPHLCK_00808	2.4e-160	-	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	DNA / pantothenate metabolism flavoprotein
DEMPHLCK_00809	9.7e-279	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
DEMPHLCK_00810	1.94e-104	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
DEMPHLCK_00811	2.48e-173	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
DEMPHLCK_00812	0.0	-	-	-	L	-	-	-	Polyphosphate kinase 2 (PPK2)
DEMPHLCK_00813	0.0	-	-	-	S	-	-	-	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
DEMPHLCK_00814	2.31e-259	-	-	-	M	-	-	-	Peptidase family M23
DEMPHLCK_00816	8.37e-126	-	4.1.1.36	-	H	ko:K01598	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Flavoprotein
DEMPHLCK_00817	1.31e-81	-	-	-	DJ	-	-	-	Addiction module toxin, RelE StbE family
DEMPHLCK_00818	2.34e-208	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
DEMPHLCK_00820	1.26e-139	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
DEMPHLCK_00821	0.0	-	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DEMPHLCK_00822	4.75e-245	-	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR synthase related protein, N-terminal domain
DEMPHLCK_00823	1.84e-105	-	-	-	S	ko:K15977	-	ko00000	DoxX
DEMPHLCK_00824	9.94e-243	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
DEMPHLCK_00825	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
DEMPHLCK_00826	1.02e-174	-	-	-	-	-	-	-	-
DEMPHLCK_00827	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DbpA RNA binding domain
DEMPHLCK_00828	0.0	-	-	-	P	ko:K01138	-	ko00000,ko01000	PA14 domain
DEMPHLCK_00829	6.18e-150	-	-	-	L	-	-	-	Membrane
DEMPHLCK_00832	0.0	gcvP	1.4.4.2	-	E	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DEMPHLCK_00833	6.67e-86	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
DEMPHLCK_00834	2.85e-267	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Aminomethyltransferase folate-binding domain
DEMPHLCK_00835	1.11e-261	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DEMPHLCK_00836	9.59e-216	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
DEMPHLCK_00837	6.26e-269	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
DEMPHLCK_00838	1.21e-268	-	-	-	M	-	-	-	Glycosyl transferase 4-like
DEMPHLCK_00839	1.18e-224	-	-	-	M	ko:K07276	-	ko00000	Mitochondrial fission ELM1
DEMPHLCK_00840	1.59e-269	-	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
DEMPHLCK_00841	1.11e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DEMPHLCK_00842	2.11e-121	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DEMPHLCK_00843	4.36e-142	-	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S4/S9 N-terminal domain
DEMPHLCK_00844	4.02e-191	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
DEMPHLCK_00849	4.37e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
DEMPHLCK_00850	0.0	-	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
DEMPHLCK_00851	7.21e-290	-	3.5.1.42	-	S	ko:K03742	ko00760,map00760	ko00000,ko00001,ko01000	Competence-damaged protein
DEMPHLCK_00852	5.7e-153	-	-	-	O	-	-	-	methyltransferase activity
DEMPHLCK_00853	1.6e-182	-	-	-	U	ko:K20276	ko02024,map02024	ko00000,ko00001	domain, Protein
DEMPHLCK_00854	0.0	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
DEMPHLCK_00855	6.16e-261	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Elongator protein 3, MiaB family, Radical SAM
DEMPHLCK_00856	1.1e-197	-	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SRP54-type protein, GTPase domain
DEMPHLCK_00857	8.13e-206	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DEMPHLCK_00858	8.55e-104	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
DEMPHLCK_00859	9.59e-288	-	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase II
DEMPHLCK_00860	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), anti-codon binding domain
DEMPHLCK_00861	0.0	-	-	-	-	-	-	-	-
DEMPHLCK_00862	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
DEMPHLCK_00863	5.67e-258	-	-	-	S	-	-	-	ankyrin repeats
DEMPHLCK_00864	1.05e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
DEMPHLCK_00865	1.06e-44	-	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S21
DEMPHLCK_00866	0.0	-	2.7.1.167, 2.7.7.70	-	M	ko:K03272	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	pfkB family carbohydrate kinase
DEMPHLCK_00867	8.25e-131	-	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
DEMPHLCK_00868	6.23e-118	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Polynucleotide kinase 3 phosphatase
DEMPHLCK_00869	4.48e-223	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
DEMPHLCK_00871	6.06e-251	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
DEMPHLCK_00872	5.69e-190	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DEMPHLCK_00873	1.2e-196	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DEMPHLCK_00874	5.68e-188	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DEMPHLCK_00875	1.48e-120	-	-	-	M	ko:K06142	-	ko00000	Outer membrane protein (OmpH-like)
DEMPHLCK_00876	3.42e-196	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DEMPHLCK_00877	6.38e-151	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DEMPHLCK_00878	6.25e-144	-	-	-	-	-	-	-	-
DEMPHLCK_00879	4.86e-201	-	-	-	S	-	-	-	DisA bacterial checkpoint controller nucleotide-binding
DEMPHLCK_00881	6.94e-153	-	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	AAA domain
DEMPHLCK_00882	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
DEMPHLCK_00883	0.0	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
DEMPHLCK_00884	1.16e-178	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DEMPHLCK_00885	1.33e-174	-	-	-	NU	-	-	-	Prepilin-type N-terminal cleavage methylation domain
DEMPHLCK_00887	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	PFAM coagulation factor 5 8 type domain protein
DEMPHLCK_00888	9.86e-168	-	-	-	M	-	-	-	Peptidase family M23
DEMPHLCK_00889	1.04e-144	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DEMPHLCK_00890	7.54e-201	-	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DEMPHLCK_00893	0.0	-	-	-	S	-	-	-	Terminase
DEMPHLCK_00894	2.46e-215	-	-	-	D	ko:K19234,ko:K19236	ko01503,map01503	ko00000,ko00001,ko01002,ko01011	ErfK ybiS ycfS ynhG family protein
DEMPHLCK_00895	2.32e-151	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
DEMPHLCK_00896	3.01e-49	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal_S15
DEMPHLCK_00897	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
DEMPHLCK_00898	9.05e-313	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	PFAM CBS domain containing protein
DEMPHLCK_00899	3.4e-311	-	-	-	S	-	-	-	PFAM CBS domain containing protein
DEMPHLCK_00900	0.0	-	-	-	C	-	-	-	Cytochrome c554 and c-prime
DEMPHLCK_00901	1.63e-164	-	-	-	CO	-	-	-	Thioredoxin-like
DEMPHLCK_00902	1.1e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DEMPHLCK_00903	4.7e-156	-	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase
DEMPHLCK_00904	4.25e-238	pyrD	1.3.5.2	-	F	ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
DEMPHLCK_00905	0.0	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase alpha chain like domain
DEMPHLCK_00906	5.21e-142	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
DEMPHLCK_00907	0.0	-	4.1.1.15	-	E	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase conserved domain
DEMPHLCK_00908	0.0	-	-	-	-	-	-	-	-
DEMPHLCK_00910	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
DEMPHLCK_00912	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
DEMPHLCK_00913	0.0	-	-	-	KT	ko:K02584	ko02020,map02020	ko00000,ko00001,ko03000	Bacterial regulatory protein, Fis family
DEMPHLCK_00914	9.68e-221	-	2.5.1.21	-	I	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01006	Squalene/phytoene synthase
DEMPHLCK_00915	0.0	-	-	-	S	-	-	-	Fungal chitosanase of glycosyl hydrolase group 75
DEMPHLCK_00916	3.14e-192	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
DEMPHLCK_00917	8.38e-98	-	-	-	-	-	-	-	-
DEMPHLCK_00918	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
DEMPHLCK_00921	9.85e-147	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
DEMPHLCK_00925	1.85e-302	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	efflux transmembrane transporter activity
DEMPHLCK_00928	4.36e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Enoyl-CoA hydratase/isomerase
DEMPHLCK_00929	6.38e-258	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
DEMPHLCK_00931	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEMPHLCK_00932	4.69e-79	rsfS	-	-	S	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DEMPHLCK_00933	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DEMPHLCK_00934	7.58e-140	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease
DEMPHLCK_00935	1.14e-175	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
DEMPHLCK_00936	0.0	-	-	-	CO	-	-	-	Disulphide bond corrector protein DsbC
DEMPHLCK_00937	1.86e-94	-	-	-	O	-	-	-	OsmC-like protein
DEMPHLCK_00939	3.42e-111	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
DEMPHLCK_00940	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
DEMPHLCK_00942	2.52e-205	-	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
DEMPHLCK_00943	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
DEMPHLCK_00944	4.97e-168	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DEMPHLCK_00945	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
DEMPHLCK_00947	3.07e-155	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
DEMPHLCK_00948	2.05e-229	-	-	-	EP	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
DEMPHLCK_00949	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
DEMPHLCK_00950	9.67e-251	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
DEMPHLCK_00951	2.31e-127	-	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Recombination protein O N terminal
DEMPHLCK_00952	3.99e-183	-	-	-	S	-	-	-	Tetratricopeptide repeat
DEMPHLCK_00953	0.0	dxs	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DEMPHLCK_00954	3.08e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
DEMPHLCK_00955	0.0	-	-	-	O	-	-	-	C-terminal four TMM region of protein-O-mannosyltransferase
DEMPHLCK_00956	0.0	-	-	-	T	-	-	-	Bacterial regulatory protein, Fis family
DEMPHLCK_00957	1.82e-274	-	-	-	T	-	-	-	PAS domain
DEMPHLCK_00958	3.37e-97	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase superfamily
DEMPHLCK_00959	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	BPG-independent PGAM N-terminus (iPGM_N)
DEMPHLCK_00960	4.16e-85	-	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S12/S23
DEMPHLCK_00961	2.91e-104	-	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S7p/S5e
DEMPHLCK_00962	0.0	-	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DEMPHLCK_00963	3.67e-65	-	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S10p/S20e
DEMPHLCK_00964	3.86e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DEMPHLCK_00965	1.9e-131	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L4/L1 family
DEMPHLCK_00966	8.72e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DEMPHLCK_00967	1.85e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DEMPHLCK_00968	1.05e-58	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DEMPHLCK_00969	4.05e-152	-	-	-	-	-	-	-	-
DEMPHLCK_00970	4.97e-70	-	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
DEMPHLCK_00971	5.2e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DEMPHLCK_00972	3.42e-97	-	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DEMPHLCK_00973	2.36e-34	-	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L29 protein
DEMPHLCK_00974	2.19e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DEMPHLCK_00975	6.79e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DEMPHLCK_00976	6.2e-203	-	-	-	-	-	-	-	-
DEMPHLCK_00977	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DEMPHLCK_00978	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
DEMPHLCK_00979	2.73e-263	-	5.2.1.8	-	O	ko:K03771	-	ko00000,ko01000,ko03110	SurA N-terminal domain
DEMPHLCK_00980	3.02e-170	-	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DEMPHLCK_00981	1.67e-141	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
DEMPHLCK_00987	1.9e-62	-	-	-	L	-	-	-	bacterial (prokaryotic) histone like domain
DEMPHLCK_00988	1.71e-207	-	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
DEMPHLCK_00989	5.96e-127	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
DEMPHLCK_00990	4.32e-174	-	-	-	F	-	-	-	NUDIX domain
DEMPHLCK_00991	1.42e-149	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Putative methyltransferase
DEMPHLCK_00992	1.39e-282	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DEMPHLCK_00993	5.64e-66	-	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
DEMPHLCK_00994	6.5e-186	-	-	-	DTZ	-	-	-	EF-hand, calcium binding motif
DEMPHLCK_00995	1.31e-214	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
DEMPHLCK_00996	1.03e-14	-	-	-	E	-	-	-	LysE type translocator
DEMPHLCK_00998	9.56e-51	-	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S16
DEMPHLCK_00999	1.55e-128	aroK	2.7.1.71	-	E	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DEMPHLCK_01000	6.97e-241	-	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DEMPHLCK_01001	1.16e-78	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
DEMPHLCK_01002	4.98e-117	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
DEMPHLCK_01003	2.73e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
DEMPHLCK_01004	1.22e-246	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DEMPHLCK_01005	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
DEMPHLCK_01006	3.35e-116	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DEMPHLCK_01011	0.0	-	-	-	CO	-	-	-	Thioredoxin-like
DEMPHLCK_01015	4.88e-265	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
DEMPHLCK_01016	1.89e-255	-	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
DEMPHLCK_01017	2.84e-286	-	-	-	S	-	-	-	Phosphotransferase enzyme family
DEMPHLCK_01018	3.23e-253	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DEMPHLCK_01020	7.86e-138	-	-	-	T	-	-	-	histone H2A K63-linked ubiquitination
DEMPHLCK_01021	1.56e-127	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DEMPHLCK_01022	5.11e-222	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
DEMPHLCK_01023	3.48e-213	-	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DEMPHLCK_01024	0.0	-	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
DEMPHLCK_01025	7.64e-235	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
DEMPHLCK_01026	2.39e-314	-	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
DEMPHLCK_01027	6.62e-257	-	-	-	S	ko:K11744	-	ko00000	AI-2E family transporter
DEMPHLCK_01028	3.28e-155	gph	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
DEMPHLCK_01029	3.27e-294	-	-	-	E	-	-	-	Amino acid permease
DEMPHLCK_01030	4.07e-173	-	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiG
DEMPHLCK_01032	2.17e-201	-	-	-	S	-	-	-	SigmaW regulon antibacterial
DEMPHLCK_01033	1.93e-242	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DEMPHLCK_01035	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
DEMPHLCK_01036	0.0	-	-	-	P	-	-	-	Dimerisation domain of Zinc Transporter
DEMPHLCK_01037	1.67e-172	-	-	-	K	-	-	-	Transcriptional regulator
DEMPHLCK_01038	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DEMPHLCK_01039	6.66e-167	-	4.3.99.3	-	O	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
DEMPHLCK_01040	2.2e-173	-	2.7.13.3	-	Q	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Transposase
DEMPHLCK_01041	0.0	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
DEMPHLCK_01042	2.56e-312	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
DEMPHLCK_01043	6.99e-238	-	-	-	E	-	-	-	Aminotransferase class-V
DEMPHLCK_01044	5.45e-234	-	-	-	S	-	-	-	Conserved hypothetical protein 698
DEMPHLCK_01045	1.12e-214	-	-	-	K	-	-	-	LysR substrate binding domain
DEMPHLCK_01048	1.4e-287	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
DEMPHLCK_01049	6.01e-295	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
DEMPHLCK_01050	0.0	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
DEMPHLCK_01051	8.42e-302	-	4.2.1.129, 5.4.99.17, 5.5.1.16	-	I	ko:K06045,ko:K17811	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
DEMPHLCK_01052	4.58e-256	-	-	-	M	ko:K02022	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEMPHLCK_01053	1.1e-160	-	-	-	S	-	-	-	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DEMPHLCK_01055	5.12e-71	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
DEMPHLCK_01056	5.48e-296	-	-	-	-	-	-	-	-
DEMPHLCK_01057	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
DEMPHLCK_01059	0.0	-	-	-	T	-	-	-	pathogenesis
DEMPHLCK_01060	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DEMPHLCK_01061	5.33e-114	ywrF	-	-	S	-	-	-	FMN binding
DEMPHLCK_01062	9.27e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
DEMPHLCK_01063	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
DEMPHLCK_01064	3.11e-306	-	-	-	M	-	-	-	OmpA family
DEMPHLCK_01065	0.0	-	6.3.2.45	-	M	ko:K02558	-	ko00000,ko01000	Mur ligase family, catalytic domain
DEMPHLCK_01066	6.55e-221	-	-	-	E	-	-	-	Phosphoserine phosphatase
DEMPHLCK_01067	6.31e-171	-	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
DEMPHLCK_01070	6.68e-198	-	2.5.1.55	-	M	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	DAHP synthetase I family
DEMPHLCK_01071	9.04e-171	cbiX	4.99.1.3	-	S	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	sirohydrochlorin cobaltochelatase activity
DEMPHLCK_01072	5.88e-163	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S2
DEMPHLCK_01073	7.15e-199	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DEMPHLCK_01074	2.65e-174	-	-	-	E	-	-	-	ATPases associated with a variety of cellular activities
DEMPHLCK_01076	4.53e-284	-	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate synthase
DEMPHLCK_01077	0.0	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
DEMPHLCK_01078	0.0	-	-	-	O	-	-	-	Trypsin
DEMPHLCK_01079	4.99e-274	-	-	-	-	-	-	-	-
DEMPHLCK_01080	1.53e-146	-	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
DEMPHLCK_01081	0.0	-	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase family (aconitate hydratase)
DEMPHLCK_01082	7.14e-141	-	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
DEMPHLCK_01083	1.92e-238	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
DEMPHLCK_01084	1.15e-238	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DEMPHLCK_01085	1.8e-216	-	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	POTRA domain, FtsQ-type
DEMPHLCK_01086	4.13e-228	ddl	6.3.2.4	-	M	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	D-ala D-ala ligase N-terminus
DEMPHLCK_01087	0.0	murB	-	-	M	-	-	-	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
DEMPHLCK_01088	3.91e-267	-	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DEMPHLCK_01089	1.33e-277	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Cell cycle protein
DEMPHLCK_01090	8.21e-160	mltD	-	CBM50	M	ko:K08307,ko:K12204,ko:K19224	-	ko00000,ko01000,ko01002,ko01011,ko02044	LysM domain
DEMPHLCK_01091	2.48e-315	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DEMPHLCK_01092	8.1e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DEMPHLCK_01093	0.0	-	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Mur ligase middle domain
DEMPHLCK_01094	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DEMPHLCK_01095	0.0	-	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein dimerisation domain
DEMPHLCK_01097	0.0	rsmH	2.1.1.199	-	M	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DEMPHLCK_01098	4.54e-105	-	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
DEMPHLCK_01099	5.27e-189	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
DEMPHLCK_01100	2.82e-154	-	-	-	S	-	-	-	UPF0126 domain
DEMPHLCK_01101	3.95e-13	-	-	-	S	-	-	-	Mac 1
DEMPHLCK_01102	1.42e-227	-	-	-	B	-	-	-	positive regulation of histone acetylation
DEMPHLCK_01103	7.91e-305	mnmE	-	-	J	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DEMPHLCK_01104	2.72e-263	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DEMPHLCK_01105	1.24e-195	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DEMPHLCK_01106	2.94e-184	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
DEMPHLCK_01107	4.96e-271	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
DEMPHLCK_01108	1.77e-142	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
DEMPHLCK_01109	6.03e-270	-	-	-	M	-	-	-	Glycosyl transferases group 1
DEMPHLCK_01110	2.21e-264	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
DEMPHLCK_01111	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
DEMPHLCK_01113	5.94e-235	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
DEMPHLCK_01114	3.78e-248	-	-	-	M	-	-	-	Glycosyl transferase, family 2
DEMPHLCK_01115	1.27e-207	MA20_42350	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyl transferase, family 2
DEMPHLCK_01116	1.83e-282	-	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	FAD binding domain
DEMPHLCK_01117	9.5e-239	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEMPHLCK_01118	3.4e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DEMPHLCK_01122	1.7e-13	-	-	-	K	-	-	-	Restriction-modification system regulatory protein
DEMPHLCK_01128	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
DEMPHLCK_01129	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR/Asp-box repeat
DEMPHLCK_01130	8.38e-276	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
DEMPHLCK_01131	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	exo-alpha-(2->6)-sialidase activity
DEMPHLCK_01133	2.28e-79	-	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
DEMPHLCK_01134	0.0	-	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	NAD synthase
DEMPHLCK_01135	7.18e-182	-	-	-	Q	-	-	-	methyltransferase activity
DEMPHLCK_01137	3.15e-137	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
DEMPHLCK_01138	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
DEMPHLCK_01139	6.13e-194	-	-	-	-	-	-	-	-
DEMPHLCK_01140	4.91e-121	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	G/U mismatch-specific uracil-DNA glycosylase activity
DEMPHLCK_01141	3.12e-224	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
DEMPHLCK_01142	2.88e-116	hisI	3.5.4.19	-	E	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-AMP cyclohydrolase
DEMPHLCK_01143	1.18e-170	-	-	-	S	ko:K05807	-	ko00000,ko02000	Outer membrane lipoprotein
DEMPHLCK_01144	7.51e-116	-	-	-	S	-	-	-	Lipopolysaccharide-assembly
DEMPHLCK_01145	4.14e-164	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Tetrapyrrole (Corrin/Porphyrin) Methylases
DEMPHLCK_01146	3.23e-182	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
DEMPHLCK_01147	2.72e-18	-	-	-	-	-	-	-	-
DEMPHLCK_01148	0.0	-	-	-	P	ko:K07221	-	ko00000,ko02000	Phosphate-selective porin O and P
DEMPHLCK_01149	3.86e-162	rnc	3.1.26.3	-	K	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DEMPHLCK_01150	1.53e-120	actI	1.5.1.36	-	S	ko:K00484	ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220	ko00000,ko00001,ko01000	FMN binding
DEMPHLCK_01151	1.57e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DEMPHLCK_01152	8.17e-147	-	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
DEMPHLCK_01153	2.3e-142	-	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Cytidylate kinase
DEMPHLCK_01154	0.0	-	-	-	I	-	-	-	Acetyltransferase (GNAT) domain
DEMPHLCK_01155	1.21e-209	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DEMPHLCK_01156	4.34e-202	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
DEMPHLCK_01157	0.0	-	-	-	GK	-	-	-	carbohydrate kinase activity
DEMPHLCK_01158	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
DEMPHLCK_01160	2.66e-290	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DEMPHLCK_01161	3.36e-130	-	-	-	D	ko:K06287	-	ko00000	Maf-like protein
DEMPHLCK_01162	0.0	-	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
DEMPHLCK_01175	5.46e-22	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
DEMPHLCK_01176	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
DEMPHLCK_01177	0.0	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
DEMPHLCK_01178	4.14e-229	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
DEMPHLCK_01179	2.47e-101	-	-	-	-	-	-	-	-
DEMPHLCK_01180	2.15e-192	-	-	-	P	ko:K09820	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
DEMPHLCK_01181	6.95e-183	-	-	-	P	ko:K09819	-	ko00000,ko00002,ko02000	FecCD transport family
DEMPHLCK_01182	5.46e-126	-	-	-	S	ko:K19411	-	ko00000	UvrB/uvrC motif
DEMPHLCK_01183	2.26e-243	-	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	ATP:guanido phosphotransferase, C-terminal catalytic domain
DEMPHLCK_01184	0.0	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
DEMPHLCK_01185	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-L-fucosidase
DEMPHLCK_01186	1.93e-63	-	-	-	P	ko:K03972	-	ko00000	Rhodanese Homology Domain
DEMPHLCK_01187	2.1e-201	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
DEMPHLCK_01188	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
DEMPHLCK_01189	1.28e-223	-	-	-	CO	-	-	-	amine dehydrogenase activity
DEMPHLCK_01190	8.39e-89	-	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
DEMPHLCK_01191	2.05e-163	-	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
DEMPHLCK_01192	7.55e-206	-	-	-	GM	-	-	-	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DEMPHLCK_01193	2.41e-232	-	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (W and Y)
DEMPHLCK_01194	1.56e-103	-	-	-	T	-	-	-	Universal stress protein family
DEMPHLCK_01195	1.45e-190	-	-	-	S	ko:K09769	-	ko00000	YmdB-like protein
DEMPHLCK_01196	4.13e-184	-	-	-	H	ko:K22132	-	ko00000,ko03016	ThiF family
DEMPHLCK_01197	9.9e-121	-	-	-	-	-	-	-	-
DEMPHLCK_01199	1.12e-229	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
DEMPHLCK_01200	3.22e-124	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
DEMPHLCK_01201	3.77e-289	kbl	2.3.1.29	-	E	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
DEMPHLCK_01202	0.0	-	-	-	KLT	-	-	-	Sulfatase-modifying factor enzyme 1
DEMPHLCK_01203	1.06e-182	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
DEMPHLCK_01204	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
DEMPHLCK_01213	1.5e-30	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
DEMPHLCK_01231	2.62e-21	-	-	-	OU	-	-	-	Serine dehydrogenase proteinase
DEMPHLCK_01236	4.01e-71	-	-	-	S	-	-	-	Phage terminase large subunit (GpA)
DEMPHLCK_01238	7.88e-98	-	-	-	D	-	-	-	Filamentation induced by cAMP protein fic
DEMPHLCK_01249	1.04e-54	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
DEMPHLCK_01250	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DEMPHLCK_01251	0.0	-	-	-	M	ko:K02847,ko:K13009,ko:K16705	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
DEMPHLCK_01252	8.67e-85	-	-	-	S	-	-	-	Protein of unknown function, DUF488
DEMPHLCK_01253	3.43e-234	-	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Porphobilinogen deaminase, dipyromethane cofactor binding domain
DEMPHLCK_01254	2.33e-239	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Glutamyl-tRNAGlu reductase, N-terminal domain
DEMPHLCK_01255	1.02e-178	-	-	-	S	-	-	-	Cytochrome C assembly protein
DEMPHLCK_01256	3.84e-189	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Type I GTP cyclohydrolase folE2
DEMPHLCK_01257	4.52e-49	-	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S18
DEMPHLCK_01258	5.67e-33	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
DEMPHLCK_01259	1.46e-118	-	-	-	T	-	-	-	Prokaryotic dksA/traR C4-type zinc finger
DEMPHLCK_01260	5.9e-232	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
DEMPHLCK_01261	2.86e-245	sun	2.1.1.176, 2.1.1.178	-	J	ko:K03500,ko:K11392	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DEMPHLCK_01262	1.79e-122	-	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
DEMPHLCK_01263	2.34e-97	nudI	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	GDP-mannose mannosyl hydrolase activity
DEMPHLCK_01265	2.88e-283	-	-	-	M	ko:K02005	-	ko00000	HlyD family secretion protein
DEMPHLCK_01266	2.12e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DEMPHLCK_01267	2.69e-310	-	-	-	V	-	-	-	MacB-like periplasmic core domain
DEMPHLCK_01268	8.19e-316	-	-	-	MU	-	-	-	Outer membrane efflux protein
DEMPHLCK_01269	1.57e-284	-	-	-	V	-	-	-	Beta-lactamase
DEMPHLCK_01270	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DEMPHLCK_01271	6.02e-283	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEMPHLCK_01272	1.02e-94	-	-	-	K	-	-	-	DNA-binding transcription factor activity
DEMPHLCK_01273	2.51e-167	-	-	-	S	-	-	-	Uncharacterised protein family UPF0066
DEMPHLCK_01274	1.37e-306	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydro-orotase-like
DEMPHLCK_01275	1.55e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
DEMPHLCK_01276	1.15e-122	-	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Phosphoribosyl transferase domain
DEMPHLCK_01277	3.73e-90	-	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR carboxylase
DEMPHLCK_01279	0.0	-	-	-	H	ko:K07137	-	ko00000	5-formyltetrahydrofolate cyclo-ligase activity
DEMPHLCK_01280	6.45e-268	-	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
DEMPHLCK_01281	2.11e-89	-	-	-	-	-	-	-	-
DEMPHLCK_01282	0.0	rseP	3.4.21.116	-	M	ko:K06399,ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	metalloendopeptidase activity
DEMPHLCK_01283	1.7e-297	-	-	-	S	-	-	-	AI-2E family transporter
DEMPHLCK_01284	0.0	-	-	-	P	-	-	-	Domain of unknown function
DEMPHLCK_01286	2.25e-111	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
DEMPHLCK_01287	1.93e-313	-	-	-	G	-	-	-	cellulose 1,4-beta-cellobiosidase activity
DEMPHLCK_01288	4.02e-188	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
DEMPHLCK_01290	1.83e-74	-	-	-	-	-	-	-	-
DEMPHLCK_01291	0.0	-	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	DNA Topoisomerase IV
DEMPHLCK_01293	9.46e-135	-	-	-	S	-	-	-	Glycosyl hydrolase 108
DEMPHLCK_01296	1.24e-200	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
DEMPHLCK_01297	5.07e-235	-	-	-	S	-	-	-	Peptidase family M28
DEMPHLCK_01298	0.0	-	-	-	M	-	-	-	Aerotolerance regulator N-terminal
DEMPHLCK_01299	0.0	-	-	-	S	-	-	-	Large extracellular alpha-helical protein
DEMPHLCK_01302	1.11e-235	-	-	-	S	ko:K14347	-	ko00000,ko02000,ko04147	SBF-like CPA transporter family (DUF4137)
DEMPHLCK_01303	2.64e-272	-	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	tRNA synthetases class I (W and Y)
DEMPHLCK_01304	1.74e-85	-	-	-	S	ko:K09922	-	ko00000	Putative member of DMT superfamily (DUF486)
DEMPHLCK_01305	4.4e-211	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
DEMPHLCK_01306	1.6e-217	-	-	-	EP	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DEMPHLCK_01307	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
DEMPHLCK_01308	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
DEMPHLCK_01309	1.53e-219	-	-	-	O	-	-	-	Thioredoxin-like domain
DEMPHLCK_01310	4.57e-311	-	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase C-terminal domain
DEMPHLCK_01311	1.75e-235	-	-	-	S	ko:K01128	-	ko00000,ko01000	acid phosphatase activity
DEMPHLCK_01315	0.0	-	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Tubulin/FtsZ family, GTPase domain
DEMPHLCK_01316	3.38e-294	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DEMPHLCK_01317	1.72e-147	-	-	-	M	-	-	-	NLP P60 protein
DEMPHLCK_01318	0.0	-	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
DEMPHLCK_01319	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
DEMPHLCK_01320	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
DEMPHLCK_01321	0.0	-	-	-	H	-	-	-	NAD synthase
DEMPHLCK_01322	7.86e-174	-	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease MlaE
DEMPHLCK_01323	4.3e-190	-	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
DEMPHLCK_01324	1.33e-231	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MlaD protein
DEMPHLCK_01325	2.69e-38	-	-	-	T	-	-	-	ribosome binding
DEMPHLCK_01328	5.1e-265	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
DEMPHLCK_01329	9.11e-261	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
DEMPHLCK_01330	2.88e-249	ppiD	5.2.1.8	-	O	ko:K03769,ko:K03770,ko:K03771,ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl cis-trans isomerase activity
DEMPHLCK_01332	0.0	-	-	-	-	-	-	-	-
DEMPHLCK_01333	2.4e-180	kdsB	2.7.7.38	-	M	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DEMPHLCK_01334	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DEMPHLCK_01335	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
DEMPHLCK_01336	0.0	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
DEMPHLCK_01338	1.04e-109	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DEMPHLCK_01339	8.76e-126	-	-	-	-	-	-	-	-
DEMPHLCK_01340	0.0	-	-	-	U	ko:K03321	-	ko00000,ko02000	Sulfate permease family
DEMPHLCK_01341	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase C-terminal
DEMPHLCK_01342	1.45e-162	-	-	-	S	-	-	-	SWIM zinc finger
DEMPHLCK_01343	0.0	-	-	-	-	-	-	-	-
DEMPHLCK_01344	1.73e-307	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DEMPHLCK_01345	1.47e-204	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
DEMPHLCK_01346	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
DEMPHLCK_01347	3.29e-258	-	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
DEMPHLCK_01348	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
DEMPHLCK_01349	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DEMPHLCK_01350	3.31e-303	-	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	tRNA (Uracil-5-)-methyltransferase
DEMPHLCK_01353	0.0	-	-	-	-	-	-	-	-
DEMPHLCK_01354	7.36e-55	himA	-	-	L	ko:K03530,ko:K04764,ko:K05788	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
DEMPHLCK_01355	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
DEMPHLCK_01356	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
DEMPHLCK_01357	2.68e-110	-	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
DEMPHLCK_01358	0.0	-	-	-	T	-	-	-	Histidine kinase
DEMPHLCK_01359	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
DEMPHLCK_01360	1.07e-188	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
DEMPHLCK_01361	3.8e-43	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	CTP reductase activity
DEMPHLCK_01362	0.0	-	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
DEMPHLCK_01363	0.0	-	-	-	M	-	-	-	Glycosyl Hydrolase Family 88
DEMPHLCK_01364	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1705)
DEMPHLCK_01366	1.96e-121	ngr	-	-	C	-	-	-	Rubrerythrin
DEMPHLCK_01368	8.88e-268	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
DEMPHLCK_01369	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
DEMPHLCK_01370	4.06e-287	-	-	-	EGP	-	-	-	Major facilitator Superfamily
DEMPHLCK_01371	2.05e-277	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
DEMPHLCK_01372	3.06e-85	-	-	-	M	ko:K03282	-	ko00000,ko02000	Large-conductance mechanosensitive channel, MscL
DEMPHLCK_01373	1.95e-312	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
DEMPHLCK_01374	1.2e-105	-	-	-	S	-	-	-	ACT domain protein
DEMPHLCK_01375	9.29e-132	-	-	-	J	ko:K02356	-	ko00000,ko03012	Elongation factor P (EF-P) OB domain
DEMPHLCK_01376	1.16e-244	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
DEMPHLCK_01377	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
DEMPHLCK_01378	0.0	-	-	-	L	ko:K03631	-	ko00000,ko03400	RecF/RecN/SMC N terminal domain
DEMPHLCK_01379	3.05e-189	-	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Metallo-beta-lactamase superfamily
DEMPHLCK_01380	5.06e-192	-	-	-	M	-	-	-	Glycosyl transferase WecB/TagA/CpsF family
DEMPHLCK_01381	2.28e-170	yyaQ	-	-	V	-	-	-	Protein conserved in bacteria
DEMPHLCK_01382	4.67e-91	-	-	-	-	-	-	-	-
DEMPHLCK_01385	4.72e-206	-	-	-	S	ko:K09949	-	ko00000	Protein of unknown function (DUF1009)
DEMPHLCK_01386	1.63e-298	-	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
DEMPHLCK_01387	9.47e-236	-	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
DEMPHLCK_01388	1.13e-221	-	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
DEMPHLCK_01389	2.52e-197	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
DEMPHLCK_01390	1e-242	-	-	-	M	ko:K18094	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	Biotin-lipoyl like
DEMPHLCK_01391	0.0	-	-	-	V	ko:K18095	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	AcrB/AcrD/AcrF family
DEMPHLCK_01392	0.0	-	-	-	S	-	-	-	pathogenesis
DEMPHLCK_01393	2.1e-99	-	-	-	S	-	-	-	peptidase
DEMPHLCK_01394	5.18e-172	-	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
DEMPHLCK_01395	2.24e-101	-	-	-	S	-	-	-	peptidase
DEMPHLCK_01396	0.0	-	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase HemD
DEMPHLCK_01397	4.53e-100	-	-	-	-	-	-	-	-
DEMPHLCK_01398	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Bacterial DNA topoisomeraes I ATP-binding domain
DEMPHLCK_01402	8.8e-169	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
DEMPHLCK_01403	0.0	-	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
DEMPHLCK_01404	2.57e-133	-	-	-	D	-	-	-	ErfK ybiS ycfS ynhG family protein
DEMPHLCK_01406	2.51e-284	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEMPHLCK_01408	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
DEMPHLCK_01409	3.36e-271	-	-	-	S	-	-	-	tRNA-splicing ligase RtcB
DEMPHLCK_01410	4.55e-213	-	-	-	K	-	-	-	LysR substrate binding domain
DEMPHLCK_01411	3.53e-295	-	-	-	EGP	-	-	-	Major facilitator Superfamily
DEMPHLCK_01413	7.1e-130	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
DEMPHLCK_01414	6.52e-75	-	-	-	L	-	-	-	Cupin 2, conserved barrel domain protein
DEMPHLCK_01415	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DEMPHLCK_01417	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Collagenase
DEMPHLCK_01418	1.53e-286	-	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
DEMPHLCK_01420	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
DEMPHLCK_01421	0.0	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 Helicase protein
DEMPHLCK_01422	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
DEMPHLCK_01423	1.77e-124	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
DEMPHLCK_01424	4.9e-207	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DEMPHLCK_01425	1.53e-47	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S L24/mitochondrial 39S L24
DEMPHLCK_01426	5.36e-138	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DEMPHLCK_01427	4.08e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DEMPHLCK_01428	2.25e-105	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DEMPHLCK_01429	2.38e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DEMPHLCK_01430	3.38e-102	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DEMPHLCK_01431	6.42e-101	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
DEMPHLCK_01433	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DEMPHLCK_01434	6.41e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DEMPHLCK_01435	1.29e-192	map	3.4.11.18	-	J	ko:K01265	-	ko00000,ko01000,ko01002	Metallopeptidase family M24
DEMPHLCK_01436	8.13e-264	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
DEMPHLCK_01437	0.0	-	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
DEMPHLCK_01438	0.0	-	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Polyphosphate kinase middle domain
DEMPHLCK_01439	1.24e-282	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
DEMPHLCK_01441	8.96e-274	-	-	GT2	S	ko:K19427	-	ko00000,ko01000	PFAM glycosyl transferase family 2
DEMPHLCK_01442	3.06e-226	-	-	-	S	-	-	-	Glycosyl transferase family 11
DEMPHLCK_01443	4.88e-263	-	-	-	S	-	-	-	Glycosyltransferase like family 2
DEMPHLCK_01444	3.37e-292	-	-	-	-	-	-	-	-
DEMPHLCK_01445	6.2e-265	-	-	-	S	-	-	-	PFAM glycosyl transferase family 2
DEMPHLCK_01446	3.93e-128	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
DEMPHLCK_01447	1.38e-230	-	-	-	C	-	-	-	e3 binding domain
DEMPHLCK_01448	4.34e-284	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DEMPHLCK_01449	4.05e-135	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DEMPHLCK_01450	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
DEMPHLCK_01451	0.0	-	-	-	T	-	-	-	5TM C-terminal transporter carbon starvation CstA
DEMPHLCK_01452	9.44e-159	-	-	-	-	-	-	-	-
DEMPHLCK_01453	0.0	-	-	-	P	-	-	-	PA14 domain
DEMPHLCK_01454	3.87e-80	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DEMPHLCK_01455	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DEMPHLCK_01456	5.58e-289	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	NusA-like KH domain
DEMPHLCK_01457	3.73e-195	-	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
DEMPHLCK_01458	1.72e-144	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DEMPHLCK_01459	2.47e-134	-	-	-	J	-	-	-	Putative rRNA methylase
DEMPHLCK_01460	2.83e-204	-	-	-	S	-	-	-	Domain of unknown function (DUF362)
DEMPHLCK_01461	0.0	-	-	-	C	-	-	-	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein
DEMPHLCK_01462	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
DEMPHLCK_01464	0.0	-	-	-	-	-	-	-	-
DEMPHLCK_01465	1.02e-184	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
DEMPHLCK_01466	7.33e-143	-	-	-	S	-	-	-	RNA recognition motif
DEMPHLCK_01467	0.0	-	-	-	M	-	-	-	Bacterial sugar transferase
DEMPHLCK_01468	8.88e-284	-	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Galactokinase galactose-binding signature
DEMPHLCK_01469	0.0	-	-	-	S	ko:K03307	-	ko00000	Sodium:solute symporter family
DEMPHLCK_01471	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
DEMPHLCK_01472	3.02e-227	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DEMPHLCK_01473	6.81e-273	-	-	-	M	-	-	-	Monogalactosyldiacylglycerol (MGDG) synthase
DEMPHLCK_01474	7.16e-174	coaX	2.7.1.33	-	K	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Type III pantothenate kinase
DEMPHLCK_01475	8.56e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
DEMPHLCK_01476	3.5e-132	-	-	-	-	-	-	-	-
DEMPHLCK_01477	5.19e-178	-	-	-	S	-	-	-	Lysin motif
DEMPHLCK_01478	1.07e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DEMPHLCK_01479	2.93e-39	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
DEMPHLCK_01480	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEMPHLCK_01482	3.69e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DEMPHLCK_01483	9.92e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DEMPHLCK_01484	1.74e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DEMPHLCK_01485	2.58e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DEMPHLCK_01486	6.29e-135	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
DEMPHLCK_01487	3.61e-46	-	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecE/Sec61-gamma subunits of protein translocation complex
DEMPHLCK_01489	9.94e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DEMPHLCK_01491	3.39e-254	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DEMPHLCK_01492	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DEMPHLCK_01493	2.5e-153	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DEMPHLCK_01494	8.38e-282	tig	-	-	O	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DEMPHLCK_01495	0.0	-	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Surface antigen
DEMPHLCK_01496	4.84e-155	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
DEMPHLCK_01497	2.6e-231	-	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
DEMPHLCK_01498	2.38e-169	-	-	-	CO	-	-	-	Protein conserved in bacteria
DEMPHLCK_01500	3.44e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
DEMPHLCK_01501	0.0	-	-	-	P	ko:K07239	-	ko00000	AcrB/AcrD/AcrF family
DEMPHLCK_01502	1.96e-297	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEMPHLCK_01503	1.01e-293	-	-	-	MU	ko:K15725	-	ko00000,ko02000	efflux transmembrane transporter activity
DEMPHLCK_01505	3.17e-206	-	-	-	G	ko:K06867,ko:K07001	-	ko00000	response to abiotic stimulus
DEMPHLCK_01506	0.0	-	-	-	E	-	-	-	PFAM major facilitator superfamily MFS_1
DEMPHLCK_01509	3.9e-214	-	-	-	KQ	-	-	-	Hypothetical methyltransferase
DEMPHLCK_01510	3.77e-291	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEMPHLCK_01511	0.0	ahcY	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DEMPHLCK_01512	3.5e-249	rgpB	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
DEMPHLCK_01513	8.88e-247	-	-	-	-	-	-	-	-
DEMPHLCK_01514	1.97e-316	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
DEMPHLCK_01515	8.66e-227	-	-	-	-	-	-	-	-
DEMPHLCK_01516	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
DEMPHLCK_01517	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RecQ zinc-binding
DEMPHLCK_01519	8.72e-301	-	-	-	M	-	-	-	Glycosyl transferases group 1
DEMPHLCK_01520	9.76e-258	-	-	-	S	-	-	-	Glycoside-hydrolase family GH114
DEMPHLCK_01521	0.0	-	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
DEMPHLCK_01522	2.86e-133	-	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	SpoU rRNA Methylase family
DEMPHLCK_01523	4.56e-206	-	3.1.1.53	-	L	ko:K03547,ko:K05970	-	ko00000,ko01000,ko03400	3'-5' exonuclease activity
DEMPHLCK_01524	4.92e-90	-	-	-	K	-	-	-	Helix-turn-helix diphteria tox regulatory element
DEMPHLCK_01525	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
DEMPHLCK_01527	2.83e-303	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
DEMPHLCK_01530	0.0	-	-	-	P	ko:K04759	-	ko00000,ko02000	Ferrous iron transport protein B C terminus
DEMPHLCK_01531	4.02e-48	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
DEMPHLCK_01532	2.48e-40	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
DEMPHLCK_01533	0.0	-	1.11.1.5	-	P	ko:K00428	-	ko00000,ko01000	Di-haem cytochrome c peroxidase
DEMPHLCK_01534	5.44e-229	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DEMPHLCK_01535	1.1e-131	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DEMPHLCK_01536	1.65e-240	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
DEMPHLCK_01537	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
DEMPHLCK_01538	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DEMPHLCK_01539	1.85e-142	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DEMPHLCK_01540	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
DEMPHLCK_01541	2.27e-245	-	-	-	-	-	-	-	-
DEMPHLCK_01542	6.11e-208	-	-	-	-	-	-	-	-
DEMPHLCK_01543	0.0	-	-	-	NU	-	-	-	Type IV pilus assembly protein PilM;
DEMPHLCK_01544	2.8e-169	-	-	-	-	-	-	-	-
DEMPHLCK_01545	9.39e-256	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
DEMPHLCK_01546	2.93e-260	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DEMPHLCK_01547	5.68e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF3313)
DEMPHLCK_01548	2.04e-314	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
DEMPHLCK_01549	1.11e-206	hisG	2.4.2.17	-	E	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
DEMPHLCK_01550	2.09e-10	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
DEMPHLCK_01551	5.8e-289	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
DEMPHLCK_01552	6.89e-168	-	-	-	T	ko:K07657	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
DEMPHLCK_01553	0.0	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Dehydratase family
DEMPHLCK_01554	0.0	-	-	-	T	-	-	-	pathogenesis
DEMPHLCK_01555	4.71e-267	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
DEMPHLCK_01556	6.59e-205	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
DEMPHLCK_01557	6.68e-286	-	4.1.99.19	-	H	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Biotin and Thiamin Synthesis associated domain
DEMPHLCK_01558	0.0	-	-	-	M	-	-	-	Sulfatase
DEMPHLCK_01559	3.09e-290	-	-	-	-	-	-	-	-
DEMPHLCK_01560	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
DEMPHLCK_01561	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2851)
DEMPHLCK_01562	6.39e-119	-	-	-	T	-	-	-	STAS domain
DEMPHLCK_01563	0.0	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
DEMPHLCK_01564	0.0	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
DEMPHLCK_01565	1.26e-247	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
DEMPHLCK_01566	0.0	-	2.1.1.182	-	IJ	ko:K02528	-	ko00000,ko01000,ko03009	Ribosomal RNA adenine dimethylases
DEMPHLCK_01567	7.2e-103	-	-	-	-	-	-	-	-
DEMPHLCK_01568	9.86e-54	-	-	-	-	-	-	-	-
DEMPHLCK_01569	1.83e-120	-	-	-	-	-	-	-	-
DEMPHLCK_01570	2.48e-300	-	-	-	V	ko:K03327	-	ko00000,ko02000	drug transmembrane transporter activity
DEMPHLCK_01571	0.0	-	-	-	P	-	-	-	Cation transport protein
DEMPHLCK_01578	1.19e-47	-	-	-	S	-	-	-	Domain of unknown function (DUF932)
DEMPHLCK_01579	3.62e-108	-	-	-	S	-	-	-	Meiotically up-regulated gene 113
DEMPHLCK_01580	2.59e-301	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
DEMPHLCK_01581	2.43e-101	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
DEMPHLCK_01582	1.23e-206	-	2.1.1.72	-	L	ko:K03427	-	ko00000,ko01000,ko02048	Putative RNA methylase family UPF0020
DEMPHLCK_01583	5.53e-96	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
DEMPHLCK_01584	4.43e-39	-	-	-	-	-	-	-	-
DEMPHLCK_01588	9.42e-07	-	-	-	S	-	-	-	TM2 domain
DEMPHLCK_01592	2.7e-60	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
DEMPHLCK_01593	2.23e-127	-	-	-	S	-	-	-	Virulence protein RhuM family
DEMPHLCK_01594	8.51e-46	-	-	-	S	-	-	-	von Willebrand factor type A domain
DEMPHLCK_01595	4.74e-07	-	-	-	KLT	-	-	-	Lanthionine synthetase C-like protein
DEMPHLCK_01596	1.11e-60	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
DEMPHLCK_01597	2.94e-31	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
DEMPHLCK_01600	4.6e-149	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
DEMPHLCK_01606	1.3e-265	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
DEMPHLCK_01608	0.0	-	-	-	M	-	-	-	pathogenesis
DEMPHLCK_01613	3.53e-255	-	-	-	S	-	-	-	Putative S-adenosyl-L-methionine-dependent methyltransferase
DEMPHLCK_01614	1.38e-226	-	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate synthetase A protein
DEMPHLCK_01615	1.26e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DEMPHLCK_01616	0.0	-	3.2.1.52	GH20	G	ko:K01207,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko01501,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map01501,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
DEMPHLCK_01618	5.32e-108	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
DEMPHLCK_01620	0.0	-	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
DEMPHLCK_01621	2.57e-251	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
DEMPHLCK_01622	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DEMPHLCK_01626	5.93e-261	-	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
DEMPHLCK_01627	8.43e-155	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
DEMPHLCK_01628	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, domain 2
DEMPHLCK_01629	1.76e-179	-	-	-	M	-	-	-	NLP P60 protein
DEMPHLCK_01630	6.77e-87	-	-	-	S	ko:K09940	-	ko00000	Domain of unknown function (DUF4870)
DEMPHLCK_01632	4.94e-75	-	-	-	C	ko:K04651	-	ko00000,ko03110	Hydrogenase/urease nickel incorporation, metallochaperone, hypA
DEMPHLCK_01633	3.4e-126	-	-	-	C	ko:K03605	-	ko00000,ko01000,ko01002	Hydrogenase maturation protease
DEMPHLCK_01634	6.49e-290	hyaC	-	-	C	ko:K03620	ko02020,map02020	ko00000,ko00001	Prokaryotic cytochrome b561
DEMPHLCK_01635	0.0	-	1.12.99.6	-	C	ko:K06281	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nickel-dependent hydrogenase
DEMPHLCK_01636	6.94e-298	-	1.12.99.6	-	C	ko:K06282	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	NiFe/NiFeSe hydrogenase small subunit C-terminal
DEMPHLCK_01637	0.0	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
DEMPHLCK_01639	9.83e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DEMPHLCK_01640	0.0	-	-	-	H	-	-	-	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DEMPHLCK_01641	0.0	-	3.4.24.3	-	NU	ko:K01387	-	ko00000,ko01000,ko01002,ko02042	translation initiation factor activity
DEMPHLCK_01642	0.0	-	-	-	M	-	-	-	Transglycosylase
DEMPHLCK_01643	2.63e-135	-	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	Peptidyl-tRNA hydrolase
DEMPHLCK_01644	4.58e-215	-	-	-	S	-	-	-	Protein of unknown function DUF58
DEMPHLCK_01645	3.82e-231	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
DEMPHLCK_01646	2.46e-216	-	3.5.1.53	-	K	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
DEMPHLCK_01648	2.36e-273	-	-	-	E	-	-	-	Alcohol dehydrogenase GroES-like domain
DEMPHLCK_01649	2.56e-309	-	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Seryl-tRNA synthetase N-terminal domain
DEMPHLCK_01651	1.47e-19	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
DEMPHLCK_01656	1.08e-266	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
DEMPHLCK_01657	0.0	yidC	-	-	O	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	serine-type endopeptidase activity
DEMPHLCK_01658	3.06e-157	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
DEMPHLCK_01659	2.76e-129	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DEMPHLCK_01660	1.02e-256	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
DEMPHLCK_01661	4.86e-230	exsH	3.2.1.178, 3.2.1.18, 3.2.1.52	GH16,GH20,GH33	G	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	xyloglucan:xyloglucosyl transferase activity
DEMPHLCK_01662	0.0	-	-	-	I	ko:K06889,ko:K09914	-	ko00000	PFAM Prenyltransferase squalene oxidase
DEMPHLCK_01663	4.24e-314	-	1.1.1.40	-	C	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Malic enzyme, NAD binding domain
DEMPHLCK_01666	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
DEMPHLCK_01667	0.0	-	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
DEMPHLCK_01668	2.14e-300	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
DEMPHLCK_01669	1.19e-92	-	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
DEMPHLCK_01670	6.17e-284	-	-	-	S	-	-	-	very-long-chain-acyl-CoA dehydrogenase activity
DEMPHLCK_01672	1.32e-296	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
DEMPHLCK_01673	6.49e-151	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
DEMPHLCK_01674	3.82e-231	-	-	-	C	-	-	-	Nitroreductase family
DEMPHLCK_01675	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
DEMPHLCK_01676	3.13e-123	-	-	-	C	-	-	-	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEMPHLCK_01677	1.55e-39	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
DEMPHLCK_01678	6.17e-237	-	-	-	M	-	-	-	Glycosyl transferase, family 2
DEMPHLCK_01679	3.34e-208	-	-	-	M	-	-	-	PFAM glycosyl transferase family 2
DEMPHLCK_01680	2.67e-113	-	-	-	S	ko:K03818	-	ko00000,ko01000	maltose O-acetyltransferase activity
DEMPHLCK_01681	0.0	-	-	-	-	-	-	-	-
DEMPHLCK_01682	3.29e-279	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
DEMPHLCK_01683	5.24e-279	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
DEMPHLCK_01684	1.32e-249	-	-	-	M	-	-	-	Glycosyl transferases group 1
DEMPHLCK_01685	2.42e-198	-	-	-	S	-	-	-	Glycosyl transferase family 11
DEMPHLCK_01686	9.16e-264	-	-	-	M	ko:K02847,ko:K13009	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
DEMPHLCK_01687	1.71e-241	-	-	-	-	-	-	-	-
DEMPHLCK_01688	9.22e-290	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
DEMPHLCK_01689	8.15e-285	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
DEMPHLCK_01690	3.33e-289	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
DEMPHLCK_01691	1.77e-191	wbyL	-	GT2	M	ko:K13002	-	ko00000,ko01000,ko01003,ko01005	transferase activity, transferring glycosyl groups
DEMPHLCK_01692	6.88e-176	-	-	-	M	-	-	-	Bacterial sugar transferase
DEMPHLCK_01693	9.48e-165	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	protein tyrosine phosphatase activity
DEMPHLCK_01694	0.0	gumC	-	-	DM	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	PFAM lipopolysaccharide biosynthesis protein
DEMPHLCK_01695	5.68e-180	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	polysaccharide export
DEMPHLCK_01696	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk_gamma
DEMPHLCK_01698	7.6e-145	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEMPHLCK_01699	1.08e-136	rbr	-	-	C	-	-	-	Rubrerythrin
DEMPHLCK_01700	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
DEMPHLCK_01702	0.0	-	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Catalase
DEMPHLCK_01703	1.01e-45	-	-	-	S	-	-	-	R3H domain
DEMPHLCK_01705	0.0	-	1.2.1.88, 1.5.5.2	-	CE	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko03000	Proline dehydrogenase
DEMPHLCK_01706	7.62e-284	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
DEMPHLCK_01707	2.92e-123	-	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
DEMPHLCK_01708	5.48e-134	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
DEMPHLCK_01709	1.71e-111	cas5d	-	-	S	ko:K19119	-	ko00000,ko02048	TIGRFAM CRISPR-associated protein Cas5
DEMPHLCK_01710	3.53e-133	-	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	DEAD-like helicases superfamily
DEMPHLCK_01711	2.22e-65	-	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	Domain of unknown function DUF83
DEMPHLCK_01712	2.12e-141	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DEMPHLCK_01713	2.15e-34	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DEMPHLCK_01727	4.63e-77	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
DEMPHLCK_01732	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
DEMPHLCK_01733	3.5e-121	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
DEMPHLCK_01734	0.0	-	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase / GMP reductase domain
DEMPHLCK_01735	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	GMP synthase C terminal domain
DEMPHLCK_01736	6.45e-138	-	-	-	S	-	-	-	Maltose acetyltransferase
DEMPHLCK_01737	6.43e-153	ppaX_1	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
DEMPHLCK_01738	2.08e-62	-	-	-	S	-	-	-	OST-HTH/LOTUS domain
DEMPHLCK_01739	1.02e-232	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
DEMPHLCK_01740	3.17e-129	-	-	-	-	-	-	-	-
DEMPHLCK_01741	6.87e-256	-	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DEMPHLCK_01742	3.3e-151	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
DEMPHLCK_01743	3.86e-76	-	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
DEMPHLCK_01744	9e-65	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DEMPHLCK_01745	5.8e-219	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
DEMPHLCK_01746	9.36e-171	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DEMPHLCK_01747	2.08e-241	-	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
DEMPHLCK_01749	1.03e-207	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
DEMPHLCK_01750	9.15e-244	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
DEMPHLCK_01751	6.79e-249	-	-	-	S	-	-	-	Glycosyltransferase like family 2
DEMPHLCK_01752	5.48e-235	-	-	GT9	M	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	ADP-heptose-lipopolysaccharide heptosyltransferase activity
DEMPHLCK_01753	2.26e-245	-	5.1.3.20	-	M	ko:K03274	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-beta hydroxysteroid dehydrogenase/isomerase family
DEMPHLCK_01754	2.74e-288	-	-	-	M	-	-	-	Glycosyltransferase like family 2
DEMPHLCK_01755	1.03e-204	-	-	-	-	-	-	-	-
DEMPHLCK_01756	5.02e-310	-	-	-	M	-	-	-	Glycosyl transferases group 1
DEMPHLCK_01757	2.57e-253	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
DEMPHLCK_01758	0.0	-	-	-	I	-	-	-	Acyltransferase family
DEMPHLCK_01759	2.8e-258	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
DEMPHLCK_01761	0.0	-	-	-	P	-	-	-	Citrate transporter
DEMPHLCK_01763	6.56e-112	-	-	-	S	ko:K08999	-	ko00000	Bifunctional nuclease
DEMPHLCK_01764	5.58e-110	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
DEMPHLCK_01765	0.0	-	-	-	E	-	-	-	Transglutaminase-like
DEMPHLCK_01766	8.77e-158	-	-	-	C	-	-	-	Nitroreductase family
DEMPHLCK_01767	0.0	-	3.2.1.23	-	G	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
DEMPHLCK_01768	4.57e-181	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
DEMPHLCK_01769	5.6e-241	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
DEMPHLCK_01770	1.41e-289	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
DEMPHLCK_01771	9.75e-316	hsrA	-	-	EGP	-	-	-	Major facilitator Superfamily
DEMPHLCK_01772	7.17e-104	yciA	-	-	I	ko:K10806	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	acyl-coa hydrolase
DEMPHLCK_01775	3.1e-207	-	-	-	IQ	-	-	-	KR domain
DEMPHLCK_01776	6.84e-248	-	-	-	M	-	-	-	Alginate lyase
DEMPHLCK_01777	9.25e-106	-	-	-	L	-	-	-	Staphylococcal nuclease homologues
DEMPHLCK_01780	3.45e-121	-	-	-	K	-	-	-	ParB domain protein nuclease
DEMPHLCK_01781	0.0	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase
DEMPHLCK_01784	2.64e-267	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
DEMPHLCK_01785	2.63e-269	-	-	-	E	-	-	-	FAD dependent oxidoreductase
DEMPHLCK_01786	1.21e-210	-	-	-	S	-	-	-	Rhomboid family
DEMPHLCK_01787	0.0	-	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
DEMPHLCK_01788	5.93e-05	-	-	-	-	-	-	-	-
DEMPHLCK_01789	0.0	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
DEMPHLCK_01790	1.32e-313	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
DEMPHLCK_01791	1.71e-264	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
DEMPHLCK_01793	8.62e-102	-	-	-	-	-	-	-	-
DEMPHLCK_01794	8.08e-236	gpsA	1.1.1.94	-	C	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
DEMPHLCK_01795	4.34e-152	-	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Glycerol-3-phosphate acyltransferase
DEMPHLCK_01796	1.02e-187	pppL	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	protein serine/threonine phosphatase activity
DEMPHLCK_01797	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
DEMPHLCK_01799	0.0	-	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DEMPHLCK_01800	1.32e-101	manC	-	-	S	-	-	-	Cupin domain
DEMPHLCK_01801	3.2e-70	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
DEMPHLCK_01802	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
DEMPHLCK_01803	3.14e-179	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DEMPHLCK_01805	0.0	-	-	-	P	-	-	-	Cation transport protein
DEMPHLCK_01806	3.52e-161	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
DEMPHLCK_01807	0.0	-	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Oligonucleotide/oligosaccharide-binding (OB)-fold
DEMPHLCK_01808	1.18e-109	-	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
DEMPHLCK_01809	0.0	-	-	-	O	-	-	-	Trypsin
DEMPHLCK_01810	4.27e-273	-	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
DEMPHLCK_01811	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DEMPHLCK_01812	9.16e-266	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	RibD C-terminal domain
DEMPHLCK_01813	9.86e-158	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
DEMPHLCK_01815	1.02e-258	-	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DEMPHLCK_01817	7.09e-251	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
DEMPHLCK_01818	0.0	-	-	-	V	-	-	-	MatE
DEMPHLCK_01819	3.05e-180	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
DEMPHLCK_01820	2.63e-84	-	-	-	M	-	-	-	Lysin motif
DEMPHLCK_01821	4.37e-203	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
DEMPHLCK_01822	1.78e-266	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2219)
DEMPHLCK_01823	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
DEMPHLCK_01824	2.66e-06	-	-	-	-	-	-	-	-
DEMPHLCK_01826	0.0	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
DEMPHLCK_01827	2.4e-167	-	-	-	T	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
DEMPHLCK_01829	0.0	-	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DEMPHLCK_01830	0.0	-	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DEMPHLCK_01831	6.76e-131	-	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DEMPHLCK_01832	7.36e-56	-	-	-	S	-	-	-	PFAM Cupin 2 conserved barrel domain protein
DEMPHLCK_01833	1.6e-92	-	-	-	L	-	-	-	IMG reference gene
DEMPHLCK_01834	2.16e-36	-	-	-	S	-	-	-	conserved domain
DEMPHLCK_01835	1.05e-15	-	-	-	M	-	-	-	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DEMPHLCK_01837	1.29e-230	-	-	-	K	-	-	-	DNA-binding transcription factor activity
DEMPHLCK_01839	0.0	-	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	C-terminal, D2-small domain, of ClpB protein
DEMPHLCK_01842	0.0	-	-	-	V	-	-	-	MatE
DEMPHLCK_01843	4.33e-161	menG	2.1.1.163, 2.1.1.201	-	Q	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	ubiE/COQ5 methyltransferase family
DEMPHLCK_01847	7.53e-201	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DEMPHLCK_01848	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DEMPHLCK_01849	1.3e-210	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DEMPHLCK_01850	3.95e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DEMPHLCK_01852	1.37e-306	-	-	-	E	ko:K03310	-	ko00000	Sodium:alanine symporter family
DEMPHLCK_01853	2.43e-95	-	-	-	K	-	-	-	-acetyltransferase
DEMPHLCK_01854	8.6e-222	-	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Glutaminase
DEMPHLCK_01855	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
DEMPHLCK_01861	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Prolyl-tRNA synthetase, C-terminal
DEMPHLCK_01862	2.04e-158	-	-	-	S	-	-	-	Peptidase family M50
DEMPHLCK_01864	2.27e-215	-	-	-	JM	-	-	-	Nucleotidyl transferase
DEMPHLCK_01865	8.25e-273	-	-	-	S	-	-	-	Phosphotransferase enzyme family
DEMPHLCK_01866	1.01e-222	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
DEMPHLCK_01868	0.0	-	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
DEMPHLCK_01869	5.87e-296	-	-	-	-	-	-	-	-
DEMPHLCK_01870	0.0	-	-	-	-	-	-	-	-
DEMPHLCK_01871	1.03e-138	mntP	-	-	P	-	-	-	manganese ion transmembrane transporter activity
DEMPHLCK_01873	4.17e-190	-	-	-	S	-	-	-	Phenazine biosynthesis-like protein
DEMPHLCK_01874	9.46e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
DEMPHLCK_01875	0.0	-	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, Activator interacting domain (AID)
DEMPHLCK_01876	5.48e-273	ycaD	-	-	EGP	ko:K08219	-	ko00000,ko02000	Major facilitator Superfamily
DEMPHLCK_01877	4.27e-225	-	3.4.11.10, 3.4.11.6	-	DZ	ko:K19701	-	ko00000,ko01000,ko01002	aminopeptidase activity
DEMPHLCK_01878	1.16e-287	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
DEMPHLCK_01879	0.0	-	-	-	S	-	-	-	inositol 2-dehydrogenase activity
DEMPHLCK_01881	6.73e-286	-	3.6.4.13	-	L	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	helicase superfamily c-terminal domain
DEMPHLCK_01883	3.6e-145	-	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
DEMPHLCK_01884	0.0	-	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEMPHLCK_01885	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
DEMPHLCK_01886	9.77e-278	-	4.2.1.51, 5.4.99.5	-	E	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
DEMPHLCK_01887	3.72e-237	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
DEMPHLCK_01888	1.91e-191	-	-	-	S	-	-	-	NIF3 (NGG1p interacting factor 3)
DEMPHLCK_01889	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
DEMPHLCK_01890	0.0	-	-	-	N	-	-	-	ABC-type uncharacterized transport system
DEMPHLCK_01891	1.01e-182	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DEMPHLCK_01892	1.09e-223	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
DEMPHLCK_01893	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DEMPHLCK_01894	2.38e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	nUDIX hydrolase
DEMPHLCK_01896	3.58e-251	-	2.3.1.1	-	E	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
DEMPHLCK_01897	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DEMPHLCK_01898	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DEMPHLCK_01900	2.11e-173	-	6.3.5.11, 6.3.5.9	-	V	ko:K02224,ko:K18554	ko00860,ko01100,ko01120,map00860,map01100,map01120	br01600,ko00000,ko00001,ko01000,ko01504	Chloramphenicol phosphotransferase-like protein
DEMPHLCK_01901	1.12e-83	-	-	-	K	ko:K07343	-	ko00000	positive regulation of type IV pilus biogenesis
DEMPHLCK_01902	5.44e-232	-	-	-	CO	-	-	-	Redoxin
DEMPHLCK_01903	1.73e-123	paiA	-	-	K	-	-	-	acetyltransferase
DEMPHLCK_01904	1.87e-215	-	-	-	K	-	-	-	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
DEMPHLCK_01906	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
DEMPHLCK_01908	0.0	-	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
DEMPHLCK_01909	0.0	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
DEMPHLCK_01910	2.1e-06	-	-	-	-	-	-	-	-
DEMPHLCK_01911	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
DEMPHLCK_01912	0.0	-	-	-	S	ko:K07126,ko:K13582	ko04112,map04112	ko00000,ko00001	beta-lactamase activity
DEMPHLCK_01914	6.58e-276	-	6.2.1.26	-	IQ	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	AMP-binding enzyme
DEMPHLCK_01915	1.27e-70	-	-	-	K	-	-	-	ribonuclease III activity
DEMPHLCK_01916	1.55e-164	-	-	-	-	-	-	-	-
DEMPHLCK_01917	3.49e-139	nuoC	1.6.5.3	-	C	ko:K00332	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEMPHLCK_01918	3.77e-138	nuoB	1.6.5.3	-	C	ko:K00331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DEMPHLCK_01922	5.17e-28	-	-	-	M	-	-	-	self proteolysis
DEMPHLCK_01924	1.02e-203	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
DEMPHLCK_01925	4.14e-175	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate reductase, N-terminus
DEMPHLCK_01926	4.21e-121	-	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
DEMPHLCK_01927	4.13e-183	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
DEMPHLCK_01928	5.03e-229	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
DEMPHLCK_01929	7.29e-211	-	-	-	M	-	-	-	Peptidase family M23
DEMPHLCK_01934	1.23e-110	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
DEMPHLCK_01935	1.26e-136	-	-	-	C	-	-	-	Nitroreductase family
DEMPHLCK_01936	0.0	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
DEMPHLCK_01937	1.66e-87	-	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
DEMPHLCK_01938	8.8e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DEMPHLCK_01939	8.07e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	tRNA (Guanine-1)-methyltransferase
DEMPHLCK_01940	2.05e-28	-	-	-	-	-	-	-	-
DEMPHLCK_01941	1.21e-238	-	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
DEMPHLCK_01942	3.94e-243	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
DEMPHLCK_01943	8.48e-56	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
DEMPHLCK_01944	0.0	-	-	-	J	ko:K07576	-	ko00000	Beta-Casp domain
DEMPHLCK_01945	1.55e-83	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	ArsC family
DEMPHLCK_01946	8.34e-180	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
DEMPHLCK_01947	0.0	-	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Carbohydrate phosphorylase
DEMPHLCK_01948	1.68e-257	tdh	1.1.1.103	-	E	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
DEMPHLCK_01949	2.31e-162	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DEMPHLCK_01951	1.62e-184	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
DEMPHLCK_01952	3.92e-115	-	-	-	-	-	-	-	-
DEMPHLCK_01955	0.0	-	-	-	L	-	-	-	DNA restriction-modification system
DEMPHLCK_01958	7.23e-164	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
DEMPHLCK_01960	1.23e-177	-	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
DEMPHLCK_01962	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
DEMPHLCK_01963	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DEMPHLCK_01964	2.76e-267	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEMPHLCK_01965	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
DEMPHLCK_01967	0.0	-	-	-	G	-	-	-	alpha-galactosidase
DEMPHLCK_01970	0.0	poxB	1.2.3.3, 1.2.5.1	-	EH	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
DEMPHLCK_01971	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEMPHLCK_01972	9.11e-182	-	-	-	L	ko:K10800	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	uracil-dna glycosylase
DEMPHLCK_01973	1.13e-228	-	2.7.1.11	-	G	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Phosphofructokinase
DEMPHLCK_01974	7.56e-271	-	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
DEMPHLCK_01975	9.14e-204	-	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DEMPHLCK_01977	0.0	-	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
DEMPHLCK_01978	9.48e-192	-	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
DEMPHLCK_01979	0.0	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
DEMPHLCK_01980	1.39e-54	-	-	-	I	-	-	-	PFAM biotin lipoyl attachment domain-containing protein
DEMPHLCK_01982	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
DEMPHLCK_01983	4.12e-100	-	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Glyoxalase-like domain
DEMPHLCK_01984	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
DEMPHLCK_01985	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DEMPHLCK_01987	0.000232	-	2.7.11.1, 2.7.11.17	-	T	ko:K08794,ko:K13412,ko:K17530	ko04626,ko04921,ko04925,ko05145,map04626,map04921,map04925,map05145	ko00000,ko00001,ko01000,ko01001	protein serine/threonine kinase activity
DEMPHLCK_01988	0.0	-	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
DEMPHLCK_01989	1.34e-298	-	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEMPHLCK_01990	3.13e-114	-	-	-	P	-	-	-	Rhodanese-like domain
DEMPHLCK_01991	1.19e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
DEMPHLCK_01992	1.76e-186	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase (SPase) II
DEMPHLCK_01993	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DEMPHLCK_01994	1e-248	-	-	-	I	-	-	-	alpha/beta hydrolase fold
DEMPHLCK_01995	9.38e-260	-	-	-	S	-	-	-	Peptidase family M28
DEMPHLCK_01996	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
DEMPHLCK_01997	5.62e-57	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
DEMPHLCK_01998	2.27e-90	-	-	-	S	ko:K09793	-	ko00000	Protein of unknown function (DUF456)
DEMPHLCK_01999	2.45e-205	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
DEMPHLCK_02000	0.0	-	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MacB-like periplasmic core domain
DEMPHLCK_02001	3.74e-208	-	-	-	S	-	-	-	RDD family
DEMPHLCK_02002	1.25e-132	-	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DEMPHLCK_02003	1.4e-171	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
DEMPHLCK_02004	5.99e-286	-	-	-	S	ko:K09760	-	ko00000	RmuC family
DEMPHLCK_02005	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Transglycosylase
DEMPHLCK_02006	1.35e-240	-	-	-	O	-	-	-	Trypsin-like peptidase domain
DEMPHLCK_02007	5.88e-277	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
DEMPHLCK_02016	3.01e-188	-	5.2.1.8	-	O	ko:K03773	-	ko00000,ko01000,ko03110	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
DEMPHLCK_02017	4.4e-138	-	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DEMPHLCK_02018	2.46e-272	-	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
DEMPHLCK_02019	2.09e-207	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
DEMPHLCK_02020	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
DEMPHLCK_02021	1.2e-167	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
DEMPHLCK_02027	1.14e-134	panZ	-	-	K	-	-	-	-acetyltransferase
DEMPHLCK_02028	2.11e-219	-	-	-	E	ko:K00612	-	ko00000,ko01000	lipolytic protein G-D-S-L family
DEMPHLCK_02029	7.15e-221	-	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
DEMPHLCK_02030	0.0	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
DEMPHLCK_02031	1.11e-175	-	-	-	-	-	-	-	-
DEMPHLCK_02033	9.55e-242	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DEMPHLCK_02034	2.63e-208	-	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Polyprenyl synthetase
DEMPHLCK_02035	1.19e-199	-	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
DEMPHLCK_02036	3.45e-157	-	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
DEMPHLCK_02037	2.45e-211	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
DEMPHLCK_02038	0.0	-	-	-	G	-	-	-	Trehalase
DEMPHLCK_02039	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
DEMPHLCK_02040	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
DEMPHLCK_02041	1.1e-34	-	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
DEMPHLCK_02042	4.9e-76	-	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	Ribonuclease P
DEMPHLCK_02043	1.09e-59	-	-	-	S	ko:K08998	-	ko00000	Haemolytic
DEMPHLCK_02044	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
DEMPHLCK_02045	0.0	-	1.4.1.13, 1.4.1.14	-	E	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
DEMPHLCK_02046	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
DEMPHLCK_02047	0.0	-	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
DEMPHLCK_02048	3.11e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase small chain, CPSase domain
DEMPHLCK_02049	6.96e-265	-	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DEMPHLCK_02050	1.31e-268	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
DEMPHLCK_02051	8.01e-294	-	-	-	C	-	-	-	Na+/H+ antiporter family
DEMPHLCK_02052	1.11e-236	-	-	-	-	-	-	-	-
DEMPHLCK_02053	3.4e-229	-	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphomannose isomerase type I
DEMPHLCK_02054	1.29e-181	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
DEMPHLCK_02055	1.93e-117	ispF	4.6.1.12	-	I	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
DEMPHLCK_02056	2.77e-180	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
DEMPHLCK_02057	0.0	-	-	-	M	-	-	-	PFAM glycosyl transferase family 51
DEMPHLCK_02058	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
DEMPHLCK_02059	6.23e-97	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
DEMPHLCK_02060	6.34e-183	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
DEMPHLCK_02061	0.0	-	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DEMPHLCK_02062	1.27e-99	-	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Predicted SPOUT methyltransferase
DEMPHLCK_02063	1.67e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S9/S16
DEMPHLCK_02064	2.79e-97	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DEMPHLCK_02065	6.12e-40	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DEMPHLCK_02066	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DEMPHLCK_02067	1.69e-174	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
DEMPHLCK_02069	4.03e-174	-	-	-	D	-	-	-	Phage-related minor tail protein
DEMPHLCK_02071	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DEMPHLCK_02072	8.25e-63	-	-	-	L	ko:K09747	-	ko00000	YbaB/EbfC DNA-binding family
DEMPHLCK_02073	1.89e-253	-	-	-	N	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease Exonuclease Phosphatase
DEMPHLCK_02074	0.0	-	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	DHHA2
DEMPHLCK_02076	5.46e-189	-	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
DEMPHLCK_02077	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
DEMPHLCK_02078	0.000651	-	-	-	-	-	-	-	-
DEMPHLCK_02079	0.0	-	-	-	G	-	-	-	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain
DEMPHLCK_02081	1.9e-256	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Iron-containing alcohol dehydrogenase
DEMPHLCK_02083	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
DEMPHLCK_02084	2.16e-180	-	-	-	C	-	-	-	Cytochrome c7 and related cytochrome c
DEMPHLCK_02085	0.0	-	-	-	C	ko:K00184	-	ko00000	4Fe-4S dicluster domain
DEMPHLCK_02087	0.0	-	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	RecG wedge domain
DEMPHLCK_02088	4.02e-166	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
DEMPHLCK_02089	0.0	pckG	4.1.1.32	-	C	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
DEMPHLCK_02091	9.05e-85	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	4'-phosphopantetheinyl transferase superfamily
DEMPHLCK_02092	5.64e-173	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DEMPHLCK_02093	0.0	-	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT/IMPCHase bienzyme
DEMPHLCK_02094	1.06e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L9, N-terminal domain
DEMPHLCK_02095	1.81e-227	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
DEMPHLCK_02096	3.2e-209	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
DEMPHLCK_02097	1.86e-19	-	-	-	S	-	-	-	Lipocalin-like
DEMPHLCK_02099	8.77e-239	cbiM	-	-	P	ko:K02007,ko:K02009,ko:K16915	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt ion transport
DEMPHLCK_02100	2.82e-194	cbiQ	-	-	P	ko:K02007,ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transmembrane transporter activity
DEMPHLCK_02101	1.96e-178	cbiO	-	-	P	ko:K02006,ko:K02008,ko:K16784,ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase activity
DEMPHLCK_02102	0.0	-	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	HELICc2
DEMPHLCK_02104	1.84e-206	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
DEMPHLCK_02105	0.0	-	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	TopoisomeraseII
DEMPHLCK_02106	1.06e-173	-	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DEMPHLCK_02107	1.98e-258	-	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
DEMPHLCK_02108	2.13e-96	-	-	-	L	ko:K07447	-	ko00000,ko01000	Likely ribonuclease with RNase H fold.
DEMPHLCK_02109	9.07e-234	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
DEMPHLCK_02110	1.45e-55	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
DEMPHLCK_02111	1.04e-49	-	-	-	-	-	-	-	-
DEMPHLCK_02112	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha galactosidase A
DEMPHLCK_02113	7.5e-221	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DEMPHLCK_02114	0.0	-	-	-	E	-	-	-	Aminotransferase class I and II
DEMPHLCK_02115	4.6e-305	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DEMPHLCK_02116	1.04e-78	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
DEMPHLCK_02117	0.0	-	-	-	P	-	-	-	Sulfatase
DEMPHLCK_02120	8.26e-154	-	-	-	K	-	-	-	Transcriptional regulator
DEMPHLCK_02121	7.18e-190	-	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
DEMPHLCK_02122	1.35e-236	-	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DEMPHLCK_02123	8.5e-121	-	-	-	M	ko:K03098	-	ko00000,ko04147	Lipocalin-like domain
DEMPHLCK_02124	2.34e-207	-	-	-	S	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
DEMPHLCK_02125	5.75e-202	-	-	-	O	-	-	-	stress-induced mitochondrial fusion
DEMPHLCK_02127	9.45e-239	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DEMPHLCK_02129	4.24e-296	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
DEMPHLCK_02130	1.49e-237	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
DEMPHLCK_02131	0.0	-	-	-	-	-	-	-	-
DEMPHLCK_02132	1.78e-241	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
DEMPHLCK_02133	0.0	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
DEMPHLCK_02134	4.72e-207	-	-	-	S	-	-	-	Protein of unknown function DUF58
DEMPHLCK_02135	0.0	-	-	-	S	-	-	-	Aerotolerance regulator N-terminal
DEMPHLCK_02136	0.0	-	-	-	S	-	-	-	von Willebrand factor type A domain
DEMPHLCK_02137	1.78e-293	-	-	-	-	-	-	-	-
DEMPHLCK_02138	2e-259	-	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
DEMPHLCK_02139	6.71e-90	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
DEMPHLCK_02140	1.02e-282	-	-	-	C	-	-	-	Aldo/keto reductase family
DEMPHLCK_02141	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
DEMPHLCK_02142	6e-142	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
DEMPHLCK_02143	7.19e-197	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
DEMPHLCK_02145	6.41e-236	-	2.7.11.1	-	T	ko:K08884,ko:K12132,ko:K20333	ko02024,map02024	ko00000,ko00001,ko01000,ko01001	PFAM Formylglycine-generating sulfatase enzyme
DEMPHLCK_02146	1.11e-262	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
DEMPHLCK_02147	2.54e-132	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DEMPHLCK_02148	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DEMPHLCK_02149	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DEMPHLCK_02150	4.52e-06	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
DEMPHLCK_02151	2.15e-183	-	-	-	I	-	-	-	Acyl-ACP thioesterase
DEMPHLCK_02152	1.72e-230	-	4.1.1.35	-	M	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	3-beta hydroxysteroid dehydrogenase/isomerase family
DEMPHLCK_02153	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
DEMPHLCK_02154	2.04e-160	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
DEMPHLCK_02156	4.89e-237	-	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
DEMPHLCK_02158	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DEMPHLCK_02159	3.29e-146	-	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DEMPHLCK_02161	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
DEMPHLCK_02162	8.71e-301	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
DEMPHLCK_02163	5.87e-163	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
DEMPHLCK_02164	6.63e-144	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
DEMPHLCK_02165	9.6e-79	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
DEMPHLCK_02166	4.43e-291	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
DEMPHLCK_02167	1.28e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
DEMPHLCK_02168	1.79e-122	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DEMPHLCK_02169	3.09e-61	-	-	-	J	-	-	-	RF-1 domain
DEMPHLCK_02170	1.67e-123	-	-	-	-	-	-	-	-
DEMPHLCK_02171	0.0	-	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP--glucose-1-phosphate uridylyltransferase
DEMPHLCK_02172	1.84e-183	-	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
DEMPHLCK_02174	1.69e-127	-	-	-	S	-	-	-	protein trimerization
DEMPHLCK_02175	2.46e-45	-	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
DEMPHLCK_02176	9.89e-66	tagD	2.7.7.39	-	H	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
DEMPHLCK_02177	1.45e-29	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	PFAM glycosyltransferase sugar-binding region containing DXD motif
DEMPHLCK_02178	1.14e-229	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
DEMPHLCK_02179	0.0	-	2.7.7.15	-	H	ko:K00968	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
DEMPHLCK_02180	1.5e-95	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
DEMPHLCK_02181	0.0	cobD	2.6.1.9, 2.7.7.74, 4.1.1.81	-	M	ko:K00817,ko:K04720,ko:K07281	ko00340,ko00350,ko00360,ko00400,ko00401,ko00562,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00562,map00860,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	nucleotidyl transferase
DEMPHLCK_02182	4.15e-262	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
DEMPHLCK_02183	0.0	-	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha amylase, C-terminal all-beta domain
DEMPHLCK_02185	1.45e-93	-	-	-	S	ko:K02426	-	ko00000	Fe-S metabolism associated domain
DEMPHLCK_02186	1.64e-223	-	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DEMPHLCK_02187	0.0	-	-	-	P	-	-	-	Sulfatase
DEMPHLCK_02188	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEMPHLCK_02189	8.72e-53	-	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
DEMPHLCK_02190	3.12e-223	hprK	-	-	T	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
DEMPHLCK_02191	0.0	-	-	-	E	-	-	-	Peptidase dimerisation domain
DEMPHLCK_02192	8.83e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DEMPHLCK_02193	1.36e-137	-	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
DEMPHLCK_02194	0.0	-	-	-	S	-	-	-	50S ribosome-binding GTPase
DEMPHLCK_02195	4.14e-163	-	-	-	S	ko:K06997	-	ko00000	Alanine racemase, N-terminal domain
DEMPHLCK_02196	1.88e-135	-	-	-	K	ko:K07735	-	ko00000,ko03000	Uncharacterized ACR, COG1678
DEMPHLCK_02197	6.07e-192	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
DEMPHLCK_02198	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
DEMPHLCK_02199	7.47e-203	-	-	-	-	-	-	-	-
DEMPHLCK_02200	8.46e-84	-	-	-	P	ko:K06195	-	ko00000	ApaG domain
DEMPHLCK_02201	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
DEMPHLCK_02202	8.26e-106	-	-	-	K	-	-	-	Lrp/AsnC ligand binding domain
DEMPHLCK_02203	1.59e-286	-	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
DEMPHLCK_02204	1.93e-209	-	-	-	S	-	-	-	CAAX protease self-immunity
DEMPHLCK_02205	3.7e-156	-	-	-	S	-	-	-	DUF218 domain
DEMPHLCK_02206	0.0	-	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Anticodon binding domain
DEMPHLCK_02207	1.16e-205	yeaE	-	-	S	-	-	-	aldo-keto reductase (NADP) activity
DEMPHLCK_02208	0.0	-	-	-	S	-	-	-	Oxygen tolerance
DEMPHLCK_02209	8.51e-42	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
DEMPHLCK_02211	6.21e-39	-	-	-	-	-	-	-	-
DEMPHLCK_02212	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DEMPHLCK_02214	9.83e-235	-	-	-	CO	-	-	-	Thioredoxin-like
DEMPHLCK_02215	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
DEMPHLCK_02216	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
DEMPHLCK_02217	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
DEMPHLCK_02218	1.6e-75	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
DEMPHLCK_02219	3.32e-210	ybfH	-	-	EG	-	-	-	spore germination
DEMPHLCK_02220	6.7e-132	-	-	-	-	-	-	-	-
DEMPHLCK_02221	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
DEMPHLCK_02222	1.47e-120	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DEMPHLCK_02223	7.48e-188	-	-	-	O	ko:K04083	-	ko00000,ko03110	Hsp33 protein
DEMPHLCK_02226	2.93e-233	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
DEMPHLCK_02230	1.39e-128	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
DEMPHLCK_02231	5.94e-178	-	4.2.99.20	-	I	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
DEMPHLCK_02232	1.46e-75	-	-	-	S	ko:K09954	-	ko00000	Putative quorum-sensing-regulated virulence factor
DEMPHLCK_02234	1.24e-51	-	-	-	-	-	-	-	-
DEMPHLCK_02235	8.46e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
DEMPHLCK_02236	1.96e-184	-	-	-	-	-	-	-	-
DEMPHLCK_02237	2.59e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
DEMPHLCK_02238	1.88e-111	-	-	-	KT	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
DEMPHLCK_02239	1.17e-304	-	-	-	C	-	-	-	4 iron, 4 sulfur cluster binding
DEMPHLCK_02240	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
DEMPHLCK_02241	1.05e-219	-	-	-	K	-	-	-	Transcriptional regulator
DEMPHLCK_02242	6.03e-178	-	-	-	C	-	-	-	aldo keto reductase
DEMPHLCK_02243	8.36e-186	-	-	-	S	-	-	-	Alpha/beta hydrolase family
DEMPHLCK_02244	2.9e-275	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
DEMPHLCK_02245	2.77e-308	-	-	-	C	-	-	-	Carboxymuconolactone decarboxylase family
DEMPHLCK_02246	2.41e-158	-	-	-	IQ	-	-	-	Short chain dehydrogenase
DEMPHLCK_02247	1.55e-24	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
DEMPHLCK_02249	4.21e-137	-	-	-	J	ko:K05808	-	ko00000,ko03009	Sigma 54 modulation/S30EA ribosomal protein C terminus
DEMPHLCK_02251	2.98e-08	-	-	-	M	-	-	-	major outer membrane lipoprotein
DEMPHLCK_02252	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
DEMPHLCK_02254	2.07e-169	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
DEMPHLCK_02255	4.52e-307	-	-	-	C	-	-	-	Sulfatase-modifying factor enzyme 1
DEMPHLCK_02256	1.6e-22	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
DEMPHLCK_02258	0.000576	-	-	-	-	-	-	-	-
DEMPHLCK_02260	7.45e-49	XK27_09985	-	-	S	-	-	-	Protein of unknown function (DUF1232)
DEMPHLCK_02261	1.43e-194	-	-	-	S	ko:K07051	-	ko00000	TatD related DNase
DEMPHLCK_02262	8.94e-56	-	-	-	-	-	-	-	-
DEMPHLCK_02263	4.83e-163	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	-
DEMPHLCK_02264	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
DEMPHLCK_02265	1.29e-187	-	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	2Fe-2S iron-sulfur cluster binding domain
DEMPHLCK_02281	9.17e-70	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
DEMPHLCK_02282	2.53e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DEMPHLCK_02283	4.62e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Amino acid kinase family
DEMPHLCK_02284	1.45e-208	-	-	-	M	-	-	-	Mechanosensitive ion channel
DEMPHLCK_02285	3.6e-152	-	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
DEMPHLCK_02286	0.0	-	-	-	S	-	-	-	Sodium:neurotransmitter symporter family
DEMPHLCK_02287	0.0	-	-	-	-	-	-	-	-
DEMPHLCK_02288	2.37e-46	-	-	-	J	-	-	-	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DEMPHLCK_02289	5.12e-145	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DEMPHLCK_02291	3.9e-306	-	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DEMPHLCK_02292	1.98e-109	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07305,ko:K12267	-	ko00000,ko01000	peptide-methionine (R)-S-oxide reductase activity
DEMPHLCK_02293	4.16e-259	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEMPHLCK_02294	6.7e-301	nupG	-	-	G	ko:K03289,ko:K03301,ko:K08218,ko:K11537	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
DEMPHLCK_02301	7.57e-247	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DEMPHLCK_02302	1.03e-243	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
DEMPHLCK_02303	0.0	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
DEMPHLCK_02304	1.37e-227	-	-	-	M	ko:K01993	-	ko00000	HlyD family secretion protein
DEMPHLCK_02305	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DEMPHLCK_02306	3.85e-194	-	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	CDP-alcohol phosphatidyltransferase
DEMPHLCK_02310	2.51e-103	-	-	-	K	-	-	-	DNA-binding transcription factor activity
DEMPHLCK_02311	3.03e-231	-	-	-	J	-	-	-	Belongs to the universal ribosomal protein uS2 family
DEMPHLCK_02312	2.13e-230	-	-	-	L	-	-	-	Elongator protein 3, MiaB family, Radical SAM
DEMPHLCK_02313	4.72e-153	-	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
DEMPHLCK_02314	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
DEMPHLCK_02316	7.65e-101	-	-	-	M	ko:K06077	-	ko00000	Glycine zipper 2TM domain
DEMPHLCK_02317	6.15e-234	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
DEMPHLCK_02318	5.19e-140	-	-	-	P	ko:K02039	-	ko00000	PhoU domain
DEMPHLCK_02319	5.24e-185	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DEMPHLCK_02320	1.51e-221	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	PBP superfamily domain
DEMPHLCK_02321	0.0	pstC	-	-	P	ko:K02037,ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DEMPHLCK_02322	0.0	-	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
DEMPHLCK_02323	8.04e-184	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DEMPHLCK_02324	1.33e-151	phoU	-	-	P	ko:K02039	-	ko00000	negative regulation of phosphate transmembrane transport
DEMPHLCK_02326	6.9e-282	-	-	-	J	-	-	-	PFAM Endoribonuclease L-PSP
DEMPHLCK_02327	0.0	-	-	-	C	-	-	-	cytochrome C peroxidase
DEMPHLCK_02328	0.0	-	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
DEMPHLCK_02329	1e-20	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	COG0010 Arginase agmatinase formimionoglutamate hydrolase arginase family
DEMPHLCK_02330	1.02e-296	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32
DEMPHLCK_02331	2.66e-147	-	-	-	C	-	-	-	lactate oxidation
DEMPHLCK_02332	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA Topoisomerase IV
DEMPHLCK_02333	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner