ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NEPIEIGG_00002 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
NEPIEIGG_00003 0.0 - - - S ko:K09704 - ko00000 Conserved protein
NEPIEIGG_00004 0.0 - - - G - - - Glycosyl hydrolase family 63 C-terminal domain
NEPIEIGG_00005 1.52e-269 phoA 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
NEPIEIGG_00006 1.94e-214 - - - S - - - Endonuclease Exonuclease phosphatase family
NEPIEIGG_00007 0.0 - - - G - - - Alpha-1,2-mannosidase
NEPIEIGG_00008 0.0 - - - J ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_00009 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00010 3.77e-194 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
NEPIEIGG_00011 1.36e-243 - 4.6.1.13 - U ko:K01771 ko00562,map00562 ko00000,ko00001,ko01000 Phosphatidylinositol-specific phospholipase C, X domain
NEPIEIGG_00012 9.1e-189 yaaA - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
NEPIEIGG_00013 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 single-stranded-DNA-specific exonuclease recJ
NEPIEIGG_00014 0.0 recQ2 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NEPIEIGG_00015 4.87e-148 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00016 1.33e-171 - - - S - - - phosphatase family
NEPIEIGG_00017 9.2e-73 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
NEPIEIGG_00018 1.68e-78 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NEPIEIGG_00019 2.29e-48 yidD - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
NEPIEIGG_00020 5.61e-147 - - - L ko:K03424 - ko00000,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_00021 8.99e-315 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NEPIEIGG_00023 4.33e-192 idnO 1.1.1.69 - IQ ko:K00046 - ko00000,ko01000 Oxidoreductase, short chain dehydrogenase reductase family protein
NEPIEIGG_00024 4.12e-294 - 3.1.1.11 - G ko:K01051 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 COG NOG24911 non supervised orthologous group
NEPIEIGG_00025 3.16e-83 - - - T - - - Psort location Cytoplasmic, score
NEPIEIGG_00026 0.0 - - - T - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_00028 3.65e-220 - - - S - - - Domain of unknown function (DUF4595) with porin-like fold
NEPIEIGG_00029 1.35e-166 pgdA_1 - - G - - - Psort location Cytoplasmic, score
NEPIEIGG_00030 0.0 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00031 5.43e-216 - - - S ko:K07133 - ko00000 AAA domain
NEPIEIGG_00032 2.38e-273 - - - S - - - ATPase (AAA superfamily)
NEPIEIGG_00033 0.0 - 3.1.1.53 - G ko:K05970 - ko00000,ko01000 COG NOG04984 non supervised orthologous group
NEPIEIGG_00034 0.0 - - - G - - - Cellulase N-terminal ig-like domain
NEPIEIGG_00035 8.57e-85 lytB - - D ko:K06381 - ko00000 SpoIID LytB domain protein
NEPIEIGG_00036 0.0 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00037 6.01e-309 - - - S - - - Protein of unknown function (DUF1343)
NEPIEIGG_00038 0.0 - - - C ko:K18930 - ko00000 FAD binding domain
NEPIEIGG_00039 2.66e-291 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00040 6.69e-202 - - - G - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00041 3.27e-188 murQ 4.2.1.126 - H ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NEPIEIGG_00042 0.0 estA - - EV - - - beta-lactamase
NEPIEIGG_00043 1.11e-154 - 5.2.1.8 - M ko:K01802,ko:K03773 - ko00000,ko01000,ko03110 FkbP-type peptidyl-prolyl cis-trans
NEPIEIGG_00044 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
NEPIEIGG_00045 0.0 bglB 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
NEPIEIGG_00046 7.75e-302 - - - P ko:K07214 - ko00000 Putative esterase
NEPIEIGG_00047 0.0 - - - E - - - Protein of unknown function (DUF1593)
NEPIEIGG_00048 4.05e-229 - - - S ko:K21572 - ko00000,ko02000 Pfam:SusD
NEPIEIGG_00049 7.18e-243 - - - PT - - - COG3712 Fe2 -dicitrate sensor, membrane component
NEPIEIGG_00050 4.28e-125 - - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog
NEPIEIGG_00051 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
NEPIEIGG_00052 4.31e-182 - 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 35 family
NEPIEIGG_00053 3.68e-284 - - - G - - - Belongs to the glycosyl hydrolase 2 family
NEPIEIGG_00054 0.0 - - - G - - - Belongs to the glycosyl hydrolase 2 family
NEPIEIGG_00055 0.0 - 3.2.1.31 - M ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 2, sugar binding domain protein
NEPIEIGG_00056 0.0 - 3.2.1.20 GH31 M ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG NOG06228 non supervised orthologous group
NEPIEIGG_00057 0.0 - - - Q - - - COG3458 Acetyl esterase (deacetylase)
NEPIEIGG_00058 1.08e-168 - - - G - - - COG COG3345 Alpha-galactosidase
NEPIEIGG_00059 5.49e-304 - - - G - - - COG COG3345 Alpha-galactosidase
NEPIEIGG_00060 0.0 - - - Q - - - FAD dependent oxidoreductase
NEPIEIGG_00061 5.62e-316 - - - MU - - - Psort location OuterMembrane, score
NEPIEIGG_00063 8.36e-90 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00064 0.0 - - - S ko:K07091 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Permease, YjgP YjgQ family
NEPIEIGG_00065 3.66e-294 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NEPIEIGG_00066 1.79e-286 aspC 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 COG0436 Aspartate tyrosine aromatic aminotransferase
NEPIEIGG_00067 1.02e-19 - - - C - - - 4Fe-4S binding domain
NEPIEIGG_00068 0.0 - - - T - - - COG0642 Signal transduction histidine kinase
NEPIEIGG_00069 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_00070 0.0 dnaX 2.7.7.7 - H ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEPIEIGG_00071 1.01e-62 - - - D - - - Septum formation initiator
NEPIEIGG_00072 2.96e-72 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_00073 1.07e-225 - - - S - - - Domain of unknown function (DUF5121)
NEPIEIGG_00074 1.27e-104 - - - - - - - -
NEPIEIGG_00075 1.91e-18 - - - - - - - -
NEPIEIGG_00076 3.94e-224 - - - - - - - -
NEPIEIGG_00077 5.94e-300 - - - L - - - Belongs to the 'phage' integrase family
NEPIEIGG_00079 3.11e-71 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_00080 2.06e-107 asnC - - K ko:K03718 - ko00000,ko03000 Transcriptional regulator, AsnC family
NEPIEIGG_00081 8.11e-203 - 5.2.1.8 - M ko:K03772,ko:K03773 - ko00000,ko01000,ko03110 Peptidyl-prolyl cis-trans isomerase
NEPIEIGG_00082 3.61e-138 fklB 5.2.1.8 - G ko:K03772,ko:K03773 - ko00000,ko01000,ko03110 Peptidyl-prolyl cis-trans isomerase
NEPIEIGG_00083 3.98e-169 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NEPIEIGG_00084 5.64e-174 - - - S - - - Glycosyltransferase, group 2 family protein
NEPIEIGG_00085 0.0 - - - M - - - Glycosyltransferase, group 1 family protein
NEPIEIGG_00086 4.28e-255 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00087 2.57e-220 - - - M ko:K07271 - ko00000,ko01000 LicD family
NEPIEIGG_00088 3.83e-229 - - - S - - - Core-2 I-Branching enzyme
NEPIEIGG_00089 0.0 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00090 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NEPIEIGG_00091 5.09e-144 - 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
NEPIEIGG_00093 3.99e-17 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
NEPIEIGG_00095 1.58e-228 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3
NEPIEIGG_00096 1.03e-167 - - - G - - - beta-galactosidase activity
NEPIEIGG_00097 0.0 - - - T - - - Y_Y_Y domain
NEPIEIGG_00098 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
NEPIEIGG_00099 0.0 - - - P - - - TonB dependent receptor
NEPIEIGG_00100 2.77e-136 - 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Glycosyl hydrolase family 26
NEPIEIGG_00101 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00102 0.0 - - - GM - - - SusD family
NEPIEIGG_00103 8.8e-211 - - - - - - - -
NEPIEIGG_00104 7.51e-100 - - - - - - - -
NEPIEIGG_00105 4.1e-156 - - - L - - - Bacterial DNA-binding protein
NEPIEIGG_00106 2.07e-255 - - - S - - - P-loop ATPase and inactivated derivatives
NEPIEIGG_00107 2.71e-19 - - - S - - - P-loop ATPase and inactivated derivatives
NEPIEIGG_00108 8.92e-273 - - - J - - - endoribonuclease L-PSP
NEPIEIGG_00109 1.58e-140 - - - S - - - Domain of unknown function (DUF4369)
NEPIEIGG_00110 0.0 - - - - - - - -
NEPIEIGG_00112 3.16e-288 - - - M - - - COG NOG07608 non supervised orthologous group
NEPIEIGG_00113 0.0 - - - M - - - Glycosyl hydrolase family 2, sugar binding domain protein
NEPIEIGG_00114 6.3e-59 - - - M - - - Glycosyl hydrolase family 2, sugar binding domain protein
NEPIEIGG_00115 3.99e-183 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 biotin acetyl-CoA-carboxylase ligase
NEPIEIGG_00116 9.39e-80 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00117 5.37e-85 - - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
NEPIEIGG_00118 4.85e-87 - - - M - - - COG0793 Periplasmic protease
NEPIEIGG_00119 2.32e-309 - - - M - - - COG0793 Periplasmic protease
NEPIEIGG_00120 7.45e-49 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00121 1.13e-93 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NEPIEIGG_00122 1.47e-56 - - - S - - - Domain of unknown function (DUF4834)
NEPIEIGG_00123 7.14e-166 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEPIEIGG_00124 1.1e-161 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NEPIEIGG_00125 2.02e-288 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
NEPIEIGG_00126 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
NEPIEIGG_00127 1.66e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NEPIEIGG_00128 1.55e-72 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00129 0.0 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEPIEIGG_00130 2.2e-25 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NEPIEIGG_00131 1.61e-173 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NEPIEIGG_00132 0.0 - 3.6.4.12 - L ko:K10742 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG COG1112 Superfamily I DNA and RNA helicases and helicase subunits
NEPIEIGG_00133 0.0 exuT - - G ko:K08191 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00134 1.03e-236 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NEPIEIGG_00135 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00136 1.17e-125 - - - K ko:K03088 - ko00000,ko03021 COG COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NEPIEIGG_00137 1.67e-272 - - - PT - - - Sigma factor regulatory protein, FecR PupR family
NEPIEIGG_00139 0.0 ybaL_1 - - PT - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00140 5.66e-168 hypB - - H ko:K22132 - ko00000,ko03016 involved in molybdopterin and thiamine biosynthesis family 1
NEPIEIGG_00141 1.34e-153 lolD - - V ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner
NEPIEIGG_00142 0.0 - - - P - - - Outer membrane protein beta-barrel family
NEPIEIGG_00143 4.24e-219 comEA - - L - - - COG COG1555 DNA uptake protein and related DNA-binding proteins
NEPIEIGG_00144 0.0 - - - P ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NEPIEIGG_00145 6.64e-91 fjo27 - - S - - - Psort location CytoplasmicMembrane, score 9.46
NEPIEIGG_00146 1.16e-302 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NEPIEIGG_00147 3.05e-200 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_00148 4.96e-171 dacA - - S - - - Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NEPIEIGG_00149 0.0 tldD1 - - S ko:K03568 - ko00000,ko01002 and their inactivated homologs
NEPIEIGG_00150 0.0 tldD3 - - S ko:K03592 - ko00000,ko01002 Psort location Cytoplasmic, score 9.26
NEPIEIGG_00151 6.39e-121 - - - P ko:K07240 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
NEPIEIGG_00152 1.4e-117 - - - P ko:K07240 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
NEPIEIGG_00153 7.94e-279 fucP - - G ko:K02429 - ko00000,ko02000 L-fucose H symporter permease
NEPIEIGG_00154 1.38e-181 - - - K - - - methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family) K00567
NEPIEIGG_00155 1.65e-94 - - - S - - - Pyridoxamine 5'-phosphate oxidase like
NEPIEIGG_00156 0.0 - - - V - - - Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NEPIEIGG_00157 0.0 - - - MU - - - Psort location OuterMembrane, score
NEPIEIGG_00158 0.0 - - - V - - - Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NEPIEIGG_00159 2.66e-250 - - - M - - - Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEPIEIGG_00160 2.31e-249 - - - M - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00163 0.0 - - - G - - - Fibronectin type III
NEPIEIGG_00164 0.0 - - - E ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_00165 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00166 3.19e-117 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NEPIEIGG_00167 0.0 - - - KT - - - Y_Y_Y domain
NEPIEIGG_00168 0.0 - - - S - - - Heparinase II/III-like protein
NEPIEIGG_00171 1.58e-301 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_00172 1.82e-243 - - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
NEPIEIGG_00173 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00174 2.15e-298 - - - S ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_00175 0.0 - - - G - - - Alpha-1,2-mannosidase
NEPIEIGG_00176 2.56e-253 - 2.4.1.319, 2.4.1.320 - G ko:K18785 - ko00000,ko01000 glycosylase
NEPIEIGG_00177 2.75e-294 ampG - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00178 0.0 - - - G - - - Alpha-1,2-mannosidase
NEPIEIGG_00180 0.0 - - - G - - - Psort location Extracellular, score
NEPIEIGG_00181 9.04e-278 - - - S - - - Concanavalin A-like lectin/glucanases superfamily
NEPIEIGG_00182 1.03e-241 - - - G - - - Putative glycoside hydrolase Family 18, chitinase_18
NEPIEIGG_00183 0.0 - - - H - - - Susd and RagB outer membrane lipoprotein
NEPIEIGG_00185 8.46e-76 - - - S - - - Fibrobacter succinogenes major domain (Fib_succ_major)
NEPIEIGG_00186 6.1e-227 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NEPIEIGG_00187 0.0 prtQ - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Psort location Cytoplasmic, score 8.96
NEPIEIGG_00188 4.82e-254 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_00189 5.64e-59 - - - - - - - -
NEPIEIGG_00190 3.8e-77 - - - S ko:K18828 - ko00000,ko01000,ko02048,ko03016 PIN domain
NEPIEIGG_00191 0.0 - - - M ko:K02014 - ko00000,ko02000 Psort location OuterMembrane, score 10.00
NEPIEIGG_00192 8.45e-140 - - - K - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEPIEIGG_00193 0.0 - - - T - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_00194 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00195 0.0 - - - E ko:K21572 - ko00000,ko02000 COG NOG25454 non supervised orthologous group
NEPIEIGG_00196 9.5e-194 - - - S ko:K06921 - ko00000 ATPase (AAA superfamily)
NEPIEIGG_00198 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00199 6.51e-259 - - - G ko:K21572 - ko00000,ko02000 Pfam:SusD
NEPIEIGG_00200 3.13e-140 - - - S - - - Zeta toxin
NEPIEIGG_00201 2.17e-35 - - - - - - - -
NEPIEIGG_00202 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 hydrolase family 2, sugar binding
NEPIEIGG_00203 1.59e-213 - - - K - - - Transcriptional regulator, AraC family
NEPIEIGG_00204 2.04e-314 - - - Q - - - COG3458 Acetyl esterase (deacetylase)
NEPIEIGG_00205 0.0 - 3.2.1.78 - G ko:K19355 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 5 (cellulase A) family
NEPIEIGG_00206 4.71e-243 eglS 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 5 (cellulase A) family
NEPIEIGG_00208 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00209 0.0 - 3.2.1.20 GH31 M ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG NOG06228 non supervised orthologous group
NEPIEIGG_00210 0.0 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase, middle domain
NEPIEIGG_00211 0.0 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase, middle domain
NEPIEIGG_00212 0.0 - - - S - - - protein conserved in bacteria
NEPIEIGG_00213 2.43e-306 - - - G - - - Glycosyl hydrolase
NEPIEIGG_00215 2.14e-33 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycoside hydrolase, family 3
NEPIEIGG_00216 7.46e-106 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NEPIEIGG_00217 3.96e-293 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NEPIEIGG_00218 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NEPIEIGG_00219 1.99e-48 cvpA - - S ko:K03558 - ko00000 Psort location CytoplasmicMembrane, score
NEPIEIGG_00220 0.0 sufB - - O ko:K09014 - ko00000 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component
NEPIEIGG_00221 1.05e-175 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component
NEPIEIGG_00222 0.0 sufD - - O ko:K09015 - ko00000 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component
NEPIEIGG_00223 1.31e-307 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family
NEPIEIGG_00224 1.25e-67 - - - S - - - Belongs to the UPF0145 family
NEPIEIGG_00225 7.26e-108 - - - S - - - COG NOG28036 non supervised orthologous group
NEPIEIGG_00227 0.0 - - - V - - - beta-lactamase
NEPIEIGG_00228 0.0 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 COG NOG04001 non supervised orthologous group
NEPIEIGG_00229 0.0 bglB_3 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
NEPIEIGG_00230 0.0 bga 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
NEPIEIGG_00231 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
NEPIEIGG_00232 1.61e-315 - - - MU - - - Efflux transporter, outer membrane factor lipoprotein, NodT family
NEPIEIGG_00233 0.0 - - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NEPIEIGG_00234 4.05e-250 - - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEPIEIGG_00235 3.44e-199 thiD 2.7.1.49, 2.7.4.7 - K ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 transcriptional regulator (AraC family)
NEPIEIGG_00236 0.0 nagZ2 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain protein
NEPIEIGG_00237 0.0 algI - - M - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00238 8.13e-230 - - - E - - - COG NOG14456 non supervised orthologous group
NEPIEIGG_00239 3.03e-227 - - - E - - - COG COG2755 Lysophospholipase L1 and related esterases
NEPIEIGG_00242 8.82e-210 eamA - - EG - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00244 1.4e-158 - - - L - - - COG COG3385 FOG Transposase and inactivated derivatives
NEPIEIGG_00245 5.57e-275 - - - - - - - -
NEPIEIGG_00246 1.39e-233 - - - K ko:K02529 - ko00000,ko03000 Psort location Cytoplasmic, score 9.26
NEPIEIGG_00247 0.0 fucI 5.3.1.25, 5.3.1.3 - G ko:K01818 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Converts the aldose L-fucose into the corresponding ketose L-fuculose
NEPIEIGG_00248 8.12e-304 - - - - - - - -
NEPIEIGG_00249 0.0 - - - G ko:K02429 - ko00000,ko02000 L-fucose H symporter permease
NEPIEIGG_00250 1.32e-295 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
NEPIEIGG_00251 6.9e-233 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_00252 1.47e-41 - - - S - - - COG NOG35393 non supervised orthologous group
NEPIEIGG_00253 2.45e-48 - - - S - - - COG NOG30994 non supervised orthologous group
NEPIEIGG_00254 1.15e-35 - - - S - - - COG NOG35214 non supervised orthologous group
NEPIEIGG_00255 1.4e-281 rhlE 3.6.4.13 - JKL ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Belongs to the DEAD box helicase family
NEPIEIGG_00256 1.36e-89 - - - S - - - Lipocalin-like domain
NEPIEIGG_00257 4.9e-105 - - - D - - - Sporulation and cell division repeat protein
NEPIEIGG_00258 3.54e-190 cysQ 3.1.3.7 - P ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 ko00000,ko00001,ko01000,ko03016 3'(2'),5'-bisphosphate nucleotidase
NEPIEIGG_00259 3.87e-303 - - - P - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00260 3.18e-134 cysC 2.7.1.25 - F ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
NEPIEIGG_00261 3.79e-220 cysD 2.7.7.4 - H ko:K00957 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase
NEPIEIGG_00265 0.0 - 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
NEPIEIGG_00266 0.0 - - - G ko:K16211 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00267 2.56e-82 cytR - - K ko:K02529,ko:K05499 - ko00000,ko03000 Psort location Cytoplasmic, score 9.97
NEPIEIGG_00268 7.86e-119 cytR - - K ko:K02529,ko:K05499 - ko00000,ko03000 Psort location Cytoplasmic, score 9.97
NEPIEIGG_00269 1.71e-311 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan endo-1,4-beta-galactosidase
NEPIEIGG_00270 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
NEPIEIGG_00273 0.0 mltD - - M ko:K08307 - ko00000,ko01000,ko01011 Transglycosylase SLT domain
NEPIEIGG_00274 8.3e-181 - - - - - - - -
NEPIEIGG_00275 4.32e-201 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NEPIEIGG_00276 2.57e-174 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain
NEPIEIGG_00277 1.08e-74 - - - S ko:K09793 - ko00000 Psort location CytoplasmicMembrane, score
NEPIEIGG_00278 0.0 - - - E - - - Domain of Unknown Function (DUF1080)
NEPIEIGG_00279 9.13e-192 surE 3.1.3.5 - S ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NEPIEIGG_00280 1.8e-269 lpxB 2.4.1.182 GT19 M ko:K00748 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NEPIEIGG_00281 2.29e-184 - - - S - - - COG NOG29298 non supervised orthologous group
NEPIEIGG_00282 1.15e-198 cdsA 2.7.7.41 - M ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NEPIEIGG_00283 1.64e-153 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NEPIEIGG_00284 5.14e-155 - - - PT - - - Domain of unknown function (DUF4974)
NEPIEIGG_00285 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00286 0.0 - - - F ko:K21572 - ko00000,ko02000 COG NOG30008 non supervised orthologous group
NEPIEIGG_00287 2.13e-160 - - - S - - - Protein of unknown function (DUF3823)
NEPIEIGG_00288 0.0 - - - S ko:K09704 - ko00000 Conserved protein
NEPIEIGG_00289 1.3e-198 - - - S - - - Domain of unknown function (DUF5040)
NEPIEIGG_00290 0.0 - - - G - - - cog cog3537
NEPIEIGG_00291 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00292 6.39e-280 - - - T - - - COG0642 Signal transduction histidine kinase
NEPIEIGG_00293 3.81e-36 rubR - - C - - - Psort location Cytoplasmic, score
NEPIEIGG_00294 0.0 - - - P ko:K03324 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00295 0.0 udk2 2.7.1.48 - FJ ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Phosphoribulokinase Uridine kinase family
NEPIEIGG_00296 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_00298 1.25e-224 dcuB - - S ko:K07791,ko:K07792 ko02020,map02020 ko00000,ko00001,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00300 6.23e-133 qacR - - K - - - transcriptional regulator, TetR family
NEPIEIGG_00301 5.8e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 with different specificities (related to short-chain alcohol
NEPIEIGG_00302 1.76e-160 rluC 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 ribosomal pseudouridine synthase C, large subunit
NEPIEIGG_00303 0.0 - - - EU - - - Peptidase, S9A B C family, catalytic domain protein
NEPIEIGG_00304 4.59e-06 - - - - - - - -
NEPIEIGG_00305 0.0 - - - T ko:K07713 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
NEPIEIGG_00306 2.51e-197 ppiA 5.2.1.8 - M ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NEPIEIGG_00307 1.35e-300 - - - S ko:K07263 - ko00000,ko01000,ko01002 Peptidase M16 inactive domain protein
NEPIEIGG_00308 1.37e-117 - - - EG - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00309 1.78e-123 - - - M - - - Nucleoside 2-deoxyribosyltransferase like
NEPIEIGG_00310 3.67e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NEPIEIGG_00311 1.94e-123 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NEPIEIGG_00312 9.08e-219 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NEPIEIGG_00313 4.95e-247 - - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEPIEIGG_00314 0.0 bepE_4 - - V ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NEPIEIGG_00315 1.32e-308 tolC - - MU - - - Psort location OuterMembrane, score
NEPIEIGG_00316 0.0 - - - E ko:K03294 - ko00000 Amino acid permease
NEPIEIGG_00317 1.25e-203 - - - I - - - COG0657 Esterase lipase
NEPIEIGG_00318 1.34e-195 - 2.7.1.33 - H ko:K09680 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenate kinase
NEPIEIGG_00319 0.0 - - - S - - - COG NOG25960 non supervised orthologous group
NEPIEIGG_00320 3.52e-222 - - - S - - - COG NOG25960 non supervised orthologous group
NEPIEIGG_00321 0.0 glnA 6.3.1.2 - S ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 Glutamate--ammonia ligase, catalytic domain protein
NEPIEIGG_00323 8.01e-162 - - - K ko:K21556 - ko00000,ko03000 - catabolite gene activator and regulatory subunit of cAMP-dependent protein
NEPIEIGG_00324 1.23e-227 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NEPIEIGG_00325 3e-145 lolA - - M ko:K03634 - ko00000 COG NOG19151 non supervised orthologous group
NEPIEIGG_00326 3.84e-255 ftsK - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related
NEPIEIGG_00327 9.73e-179 - - - L - - - Helicase C-terminal domain protein
NEPIEIGG_00328 1.97e-148 rhaR_1 - - K - - - transcriptional regulator (AraC family)
NEPIEIGG_00329 1.73e-122 ydjH_1 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family
NEPIEIGG_00330 1.22e-91 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
NEPIEIGG_00331 3.84e-49 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEPIEIGG_00332 1.15e-251 - - - C - - - Shikimate dehydrogenase substrate binding domain
NEPIEIGG_00333 6.92e-144 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
NEPIEIGG_00334 6.37e-234 - - - C - - - Aldo/keto reductase family
NEPIEIGG_00336 2.07e-37 - - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Periplasmic Protein
NEPIEIGG_00337 7.36e-118 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_00338 8.79e-281 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_00339 0.0 - - - M - - - Glycosyltransferase, group 2 family protein
NEPIEIGG_00340 0.0 - - - M - - - PQQ enzyme repeat
NEPIEIGG_00341 0.0 - - - M - - - fibronectin type III domain protein
NEPIEIGG_00342 0.0 - - - M - - - fibronectin type III domain protein
NEPIEIGG_00343 0.0 - - - E - - - Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NEPIEIGG_00344 1.8e-309 - - - S - - - protein conserved in bacteria
NEPIEIGG_00345 0.0 - - - S - - - P-loop ATPase and inactivated derivatives
NEPIEIGG_00346 1.37e-167 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NEPIEIGG_00347 1.08e-217 ddh 1.4.1.16 - E ko:K03340 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
NEPIEIGG_00348 3.47e-117 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NEPIEIGG_00349 4.97e-250 - - - S - - - COG NOG26961 non supervised orthologous group
NEPIEIGG_00350 6.89e-279 pepQ 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 xaa-pro dipeptidase K01271
NEPIEIGG_00351 0.0 gdh 1.4.1.4 - C ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
NEPIEIGG_00352 0.0 - 3.2.1.20, 3.2.1.3 GH31,GH97 G ko:K01187,ko:K21574 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl-hydrolase 97 C-terminal, oligomerisation
NEPIEIGG_00353 0.0 - - - G - - - Glycogen debranching enzyme, glucanotransferase domain
NEPIEIGG_00354 1.04e-37 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NEPIEIGG_00356 6.91e-219 corA - - P ko:K03284 - ko00000,ko02000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_00357 4.38e-146 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEPIEIGG_00358 0.0 - - - KT - - - tetratricopeptide repeat
NEPIEIGG_00360 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00361 0.0 - - - GM ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_00362 4.85e-148 lpxA 2.3.1.129 - M ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 ko00000,ko00001,ko00002,ko01000,ko01005 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NEPIEIGG_00363 0.0 fabZ 3.5.1.108, 4.2.1.59 - IM ko:K16363 ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
NEPIEIGG_00364 1.28e-161 lpxD 2.3.1.191 - M ko:K02536 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NEPIEIGG_00365 3.53e-294 - - - S ko:K06885 - ko00000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_00366 1.99e-197 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the OMP decarboxylase family. Type 2 subfamily
NEPIEIGG_00367 3.73e-263 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NEPIEIGG_00368 8.37e-280 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_00369 1.56e-124 lemA - - S ko:K03744 - ko00000 LemA family
NEPIEIGG_00370 2.51e-188 - - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
NEPIEIGG_00371 3.29e-161 - - - S ko:K06889 - ko00000 of the alpha beta superfamily
NEPIEIGG_00372 8.24e-44 - - - S ko:K06889 - ko00000 of the alpha beta superfamily
NEPIEIGG_00373 3.06e-102 - - - V - - - Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NEPIEIGG_00374 0.0 - - - V - - - Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NEPIEIGG_00375 1.71e-300 - - - MU - - - Psort location OuterMembrane, score
NEPIEIGG_00376 8.84e-285 - 4.1.1.3 - C ko:K01572 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 sodium ion-translocating decarboxylase, beta subunit
NEPIEIGG_00377 0.0 cfiA 6.4.1.1 - C ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG5016 Pyruvate oxaloacetate carboxyltransferase
NEPIEIGG_00378 6.05e-45 - 4.1.1.3 - C ko:K01573 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Sodium pump decarboxylase gamma subunit
NEPIEIGG_00379 5.56e-105 - - - L - - - DNA-binding protein
NEPIEIGG_00381 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NEPIEIGG_00382 1.1e-63 - - - E - - - non supervised orthologous group
NEPIEIGG_00383 2.08e-113 - - - S - - - protein BT4048 SWALL AAO79153 (EMBL AE016943) (373 aa) fasta scores E()
NEPIEIGG_00384 5.37e-83 - - - CO - - - amine dehydrogenase activity
NEPIEIGG_00386 3.16e-13 - - - S - - - No significant database matches
NEPIEIGG_00387 1.81e-98 - - - - - - - -
NEPIEIGG_00388 4.41e-251 - - - M - - - ompA family
NEPIEIGG_00389 2.54e-197 - - - E - - - FAD dependent oxidoreductase
NEPIEIGG_00390 6.66e-39 - - - - - - - -
NEPIEIGG_00391 2.73e-11 - - - - - - - -
NEPIEIGG_00393 1.64e-211 - - - P ko:K07217 - ko00000 Manganese containing catalase
NEPIEIGG_00394 1e-33 - - - - - - - -
NEPIEIGG_00395 1.07e-29 - - - S - - - Transglycosylase associated protein
NEPIEIGG_00397 4.57e-105 ykgB - - S - - - Psort location CytoplasmicMembrane, score 9.46
NEPIEIGG_00398 3.19e-12 ykgB - - S - - - Psort location CytoplasmicMembrane, score 9.46
NEPIEIGG_00399 6.9e-198 - - - K - - - COG COG2207 AraC-type DNA-binding domain-containing proteins
NEPIEIGG_00400 4.04e-116 - 2.1.1.130, 2.1.1.151 - H ko:K03394 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 COG2243 Precorrin-2 methylase
NEPIEIGG_00401 8.25e-91 - - - S - - - Protein of unknown function (DUF1573)
NEPIEIGG_00402 0.0 - - - S - - - oligopeptide transporter, OPT family
NEPIEIGG_00403 1.43e-220 - - - I - - - pectin acetylesterase
NEPIEIGG_00404 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 COG3250 Beta-galactosidase beta-glucuronidase
NEPIEIGG_00406 2.95e-263 argK - - E ko:K07588 - ko00000,ko01000 Lao Ao transport system ATPase
NEPIEIGG_00407 7.7e-254 - - - S - - - COG NOG19146 non supervised orthologous group
NEPIEIGG_00408 0.0 - - - S - - - COG2373 Large extracellular alpha-helical protein
NEPIEIGG_00410 1.07e-262 pepD_2 - - E ko:K01270 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Xaa-His dipeptidase
NEPIEIGG_00411 2.03e-139 - - - S - - - Protein of unknown function (DUF3823)
NEPIEIGG_00412 0.0 - 3.1.1.17 - G ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 ko00000,ko00001,ko00002,ko01000,ko04147 SMP-30/Gluconolaconase/LRE-like region
NEPIEIGG_00413 4.14e-159 - - - G - - - SMP-30/Gluconolaconase/LRE-like region
NEPIEIGG_00414 0.0 - - - G - - - SMP-30/Gluconolaconase/LRE-like region
NEPIEIGG_00415 6.23e-97 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00416 9.13e-262 - - - S - - - COG NOG26558 non supervised orthologous group
NEPIEIGG_00417 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NEPIEIGG_00418 2.71e-184 - - - K - - - COG NOG38984 non supervised orthologous group
NEPIEIGG_00419 2.1e-140 - - - S - - - COG NOG23385 non supervised orthologous group
NEPIEIGG_00420 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 COG COG3973 Superfamily I DNA and RNA helicases
NEPIEIGG_00421 1.79e-156 - - - S ko:K18234 - ko00000,ko01000,ko01504 Bacterial transferase hexapeptide repeat protein
NEPIEIGG_00422 1.86e-279 - - - V - - - COG0534 Na -driven multidrug efflux pump
NEPIEIGG_00424 1.8e-219 miaA2 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NEPIEIGG_00425 1.97e-229 - - - I - - - lipid kinase, YegS Rv2252 BmrU family
NEPIEIGG_00426 2.05e-185 kdsA 2.5.1.55 - H ko:K01627 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the KdsA family
NEPIEIGG_00430 8.89e-215 ydjH_1 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family
NEPIEIGG_00431 6.28e-271 - - - G - - - Transporter, major facilitator family protein
NEPIEIGG_00432 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NEPIEIGG_00433 5.44e-41 - 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NEPIEIGG_00434 0.0 - 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
NEPIEIGG_00435 0.0 - - - G - - - Belongs to the glycosyl hydrolase 32 family
NEPIEIGG_00436 0.0 bglX 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 glycosyl hydrolase, family 3
NEPIEIGG_00437 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00438 0.0 - - - S ko:K21572 - ko00000,ko02000 Pfam:SusD
NEPIEIGG_00439 8.18e-207 - - - S - - - Concanavalin A-like lectin/glucanases superfamily
NEPIEIGG_00440 0.0 - - - S - - - Putative glucoamylase
NEPIEIGG_00442 2.12e-172 pdxA 1.1.1.262 - C ko:K00097 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the PdxA family
NEPIEIGG_00443 7.14e-256 - - - L - - - COG NOG11654 non supervised orthologous group
NEPIEIGG_00444 6.46e-246 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NEPIEIGG_00445 0.0 ppiD 5.2.1.8 - O ko:K01802,ko:K03770 - ko00000,ko01000,ko03110 COG NOG26630 non supervised orthologous group
NEPIEIGG_00446 2.26e-286 tlyC - - S ko:K03699 - ko00000,ko02042 Psort location CytoplasmicMembrane, score
NEPIEIGG_00447 7.23e-148 - - - S - - - Lipopolysaccharide-assembly, LptC-related
NEPIEIGG_00448 2.39e-311 - - - S - - - Tetratricopeptide repeat protein
NEPIEIGG_00449 1.12e-303 - - - I - - - Psort location OuterMembrane, score
NEPIEIGG_00450 1.92e-48 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NEPIEIGG_00451 7.61e-12 - - - P - - - COG COG3119 Arylsulfatase A and related enzymes
NEPIEIGG_00452 0.0 - - - S - - - PHP domain protein
NEPIEIGG_00453 1.28e-203 ppgK 2.7.1.2, 2.7.1.63 - GK ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 9.26
NEPIEIGG_00454 1.28e-277 - - - G - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00455 0.0 hepB - - S - - - Heparinase II III-like protein
NEPIEIGG_00456 0.0 - - - P - - - COG COG3119 Arylsulfatase A and related enzymes
NEPIEIGG_00457 4.16e-317 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NEPIEIGG_00458 2.32e-109 xylB_2 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Carbohydrate kinase, FGGY family protein
NEPIEIGG_00459 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_00460 0.0 - - - P ko:K08138 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NEPIEIGG_00461 0.0 ramA_2 - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00463 3.03e-188 - - - - - - - -
NEPIEIGG_00466 3.07e-238 - 4.2.2.7 PL13 M ko:K19050 - ko00000,ko01000 Heparin lyase
NEPIEIGG_00468 0.0 porA 1.2.7.11, 1.2.7.3 - C ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 2-oxoacid acceptor oxidoreductase, alpha subunit
NEPIEIGG_00469 2.03e-251 oorB 1.2.7.11, 1.2.7.3 - C ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
NEPIEIGG_00470 5.57e-150 - - - Q - - - AMP-binding enzyme
NEPIEIGG_00471 4.7e-195 - - - Q - - - AMP-binding enzyme
NEPIEIGG_00472 6.73e-51 - - - IQ ko:K02078 - ko00000,ko00001 Phosphopantetheine attachment site
NEPIEIGG_00473 0.0 - - - M - - - MBOAT, membrane-bound O-acyltransferase family
NEPIEIGG_00474 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_00475 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00476 0.0 - - - S ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_00477 3.14e-49 - - - S - - - COG COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NEPIEIGG_00478 5.55e-210 nucA_1 - - F ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 Psort location Extracellular, score
NEPIEIGG_00479 0.0 sulP - - P ko:K03321 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00480 2.31e-86 rbr - - C - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00481 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
NEPIEIGG_00482 0.0 - - - S - - - Tetratricopeptide repeat
NEPIEIGG_00483 4.2e-79 - - - - - - - -
NEPIEIGG_00484 1.74e-83 - - - S - - - COG NOG29403 non supervised orthologous group
NEPIEIGG_00486 1.21e-87 - - - K - - - COG3279 Response regulator of the LytR AlgR family
NEPIEIGG_00487 1.11e-68 - - - K - - - COG3279 Response regulator of the LytR AlgR family
NEPIEIGG_00488 6e-70 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00489 5.73e-130 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NEPIEIGG_00490 2.47e-131 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NEPIEIGG_00491 5.91e-93 hslR - - J ko:K04762 - ko00000,ko03110 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NEPIEIGG_00492 7.89e-246 - - - S - - - Oxidoreductase, NAD-binding domain protein
NEPIEIGG_00493 0.0 nhaA - - P ko:K03455 - ko00000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00494 7.29e-292 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis bifunctional protein HisB
NEPIEIGG_00495 1.81e-251 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NEPIEIGG_00496 2.8e-294 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NEPIEIGG_00497 1.54e-53 hisG 2.4.2.17 - F ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
NEPIEIGG_00498 7.14e-180 - - - D ko:K03496 - ko00000,ko03036,ko04812 Cellulose biosynthesis protein BcsQ
NEPIEIGG_00499 6.27e-51 - - - - - - - -
NEPIEIGG_00500 5.44e-115 - - - - - - - -
NEPIEIGG_00501 5.07e-45 - - - - - - - -
NEPIEIGG_00502 1.13e-61 - - - - - - - -
NEPIEIGG_00503 3.21e-43 - - - - - - - -
NEPIEIGG_00504 6.34e-103 - - - S - - - VRR-NUC domain
NEPIEIGG_00505 1.35e-46 - - - - - - - -
NEPIEIGG_00506 1.63e-139 - - - S - - - PFAM HD domain
NEPIEIGG_00508 1.04e-285 - - - G - - - Alpha-1,2-mannosidase
NEPIEIGG_00509 1.56e-160 ampG - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major Facilitator Superfamily
NEPIEIGG_00510 9.86e-209 - 2.4.1.319, 2.4.1.320 - G ko:K18785 - ko00000,ko01000 glycosylase
NEPIEIGG_00511 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00512 0.0 - - - M ko:K21572 - ko00000,ko02000 Pfam:SusD
NEPIEIGG_00513 1.61e-296 - - - - - - - -
NEPIEIGG_00514 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Alpha galactosidase A
NEPIEIGG_00515 8.11e-262 - 3.1.3.97 - S ko:K07053 - ko00000,ko01000 Domain of unknown function
NEPIEIGG_00517 5.23e-102 - - - - - - - -
NEPIEIGG_00518 5.28e-100 - - - C - - - lyase activity
NEPIEIGG_00519 1.15e-116 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NEPIEIGG_00520 3.97e-136 rbr3A - - C - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00521 3.12e-104 fur - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NEPIEIGG_00522 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NEPIEIGG_00523 5.03e-191 - - - ET - - - COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain
NEPIEIGG_00524 0.0 - - - H - - - COG NOG07963 non supervised orthologous group
NEPIEIGG_00525 1.38e-125 porG 1.2.7.3 - C ko:K00177 ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200 br01601,ko00000,ko00001,ko00002,ko01000 2-oxoacid ferredoxin flavodoxin oxidoreductase, gamma subunit
NEPIEIGG_00526 2.54e-75 vorA 1.2.7.11, 1.2.7.3 - C ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
NEPIEIGG_00527 0.0 - - - G - - - Belongs to the glycosyl hydrolase 43 family
NEPIEIGG_00528 0.0 - - - S ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_00529 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00530 0.0 - - - KT - - - COG NOG11230 non supervised orthologous group
NEPIEIGG_00531 2.38e-39 - - - KT - - - COG NOG11230 non supervised orthologous group
NEPIEIGG_00533 1.85e-124 - - - T - - - - Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NEPIEIGG_00534 1.18e-181 - - - S - - - hydrolases of the HAD superfamily
NEPIEIGG_00535 1.62e-228 - - - K - - - transcriptional regulator (AraC family)
NEPIEIGG_00536 3.97e-312 - - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NEPIEIGG_00537 1.93e-219 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
NEPIEIGG_00538 3.8e-293 - - - S - - - COG NOG26634 non supervised orthologous group
NEPIEIGG_00539 3.72e-143 - - - S - - - Domain of unknown function (DUF4129)
NEPIEIGG_00540 2.11e-202 - - - - - - - -
NEPIEIGG_00541 8.85e-112 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00542 1.3e-94 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00543 1.05e-45 - - - S - - - serine threonine protein kinase
NEPIEIGG_00544 2.91e-245 - 3.2.1.45 GH116 G ko:K17108 ko00511,ko00600,ko01100,map00511,map00600,map01100 ko00000,ko00001,ko01000 Pfam:GBA2_N
NEPIEIGG_00545 2.84e-297 - - - S - - - COG NOG11699 non supervised orthologous group
NEPIEIGG_00546 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00547 1.02e-115 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00548 0.0 - - - P ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_00549 3.69e-188 - - - S - - - Domain of unknown function (DUF4886)
NEPIEIGG_00551 3.45e-207 xynZ - - S - - - Esterase
NEPIEIGG_00552 0.0 - - - G - - - Fibronectin type III-like domain
NEPIEIGG_00553 3.97e-224 - - - S ko:K21572 - ko00000,ko02000 Pfam:SusD
NEPIEIGG_00554 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00556 6.66e-73 - - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
NEPIEIGG_00558 3.57e-209 ftcD 2.1.2.5, 4.3.1.4 - E ko:K00603,ko:K13990 ko00340,ko00670,ko01100,map00340,map00670,map01100 ko00000,ko00001,ko01000,ko03036,ko04147 Glutamate formiminotransferase
NEPIEIGG_00559 0.0 hutU 4.2.1.49 - H ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NEPIEIGG_00560 4.8e-175 - - - - - - - -
NEPIEIGG_00561 1.29e-76 - - - S - - - Lipocalin-like
NEPIEIGG_00562 3.33e-60 - - - - - - - -
NEPIEIGG_00563 1.72e-54 - - - S - - - COG NOG18433 non supervised orthologous group
NEPIEIGG_00564 2.5e-138 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00565 2.17e-107 - - - - - - - -
NEPIEIGG_00566 1.19e-153 - - - S - - - COG NOG29571 non supervised orthologous group
NEPIEIGG_00569 0.0 - - - M - - - Psort location OuterMembrane, score
NEPIEIGG_00570 8.68e-229 - 3.1.3.2 - S ko:K14379 ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323 ko00000,ko00001,ko01000 Purple acid phosphatase
NEPIEIGG_00571 3.22e-110 - - - S - - - Domain of unknown function (DUF4784)
NEPIEIGG_00572 1.2e-123 - - - S - - - Domain of unknown function (DUF4784)
NEPIEIGG_00573 7.85e-126 mscM - - M - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00574 7.03e-88 mscM - - M - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00575 1.24e-20 mscM - - M - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00576 1.89e-204 yrbG - - P ko:K07301 - ko00000,ko02000 K -dependent Na Ca exchanger
NEPIEIGG_00577 8.96e-250 yghO - - K - - - COG NOG07967 non supervised orthologous group
NEPIEIGG_00578 5.73e-23 - - - - - - - -
NEPIEIGG_00579 1.27e-224 ispB 2.5.1.90 - H ko:K02523 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NEPIEIGG_00580 8.14e-209 deoC 4.1.2.4 - H ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NEPIEIGG_00581 1.6e-75 ypjD - - S - - - MazG nucleotide pyrophosphohydrolase domain
NEPIEIGG_00582 1.21e-104 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NEPIEIGG_00583 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NEPIEIGG_00584 1.24e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NEPIEIGG_00585 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NEPIEIGG_00587 0.0 - - - P ko:K21573 - ko00000,ko02000 TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00588 5.04e-244 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00589 4.92e-149 fahA - - Q - - - 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase, fumarylacetoacetate hydrolase family K01828
NEPIEIGG_00590 8.38e-152 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NEPIEIGG_00591 8.75e-78 - - - J ko:K03113 ko03013,map03013 ko00000,ko00001,ko03012 COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related
NEPIEIGG_00592 2.47e-225 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NEPIEIGG_00593 3.51e-187 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NEPIEIGG_00594 0.0 - - - P - - - Psort location OuterMembrane, score
NEPIEIGG_00595 3.8e-291 - - - S - - - Putative binding domain, N-terminal
NEPIEIGG_00596 2.06e-264 - - - F ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 COG1864 DNA RNA endonuclease G, NUC1
NEPIEIGG_00597 3.75e-125 - - - S - - - ATP-binding cassette protein, ChvD family
NEPIEIGG_00598 5.94e-123 - - - S - - - ATP-binding cassette protein, ChvD family
NEPIEIGG_00599 3.05e-103 - - - S - - - ATP-binding cassette protein, ChvD family
NEPIEIGG_00601 0.0 aglC 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 COG3345 Alpha-galactosidase
NEPIEIGG_00602 1.13e-37 kdsD 5.3.1.13 - M ko:K06041 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 sugar phosphate isomerase involved in capsule formation
NEPIEIGG_00603 7.54e-304 - - - S - - - Belongs to the peptidase M16 family
NEPIEIGG_00604 8.2e-145 queH 1.17.99.6 - C ko:K09765 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NEPIEIGG_00605 9.94e-287 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00606 0.0 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00607 0.0 - 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 5 (cellulase A) family
NEPIEIGG_00608 0.0 bglB 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
NEPIEIGG_00610 7.95e-291 serB 3.1.3.3 - ET ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 Psort location Cytoplasmic, score 8.96
NEPIEIGG_00611 4.56e-110 - - - O - - - COG NOG28456 non supervised orthologous group
NEPIEIGG_00612 1.78e-265 lptG - - S ko:K11720 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Permease, YjgP YjgQ family
NEPIEIGG_00613 6.13e-281 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NEPIEIGG_00614 1.97e-93 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NEPIEIGG_00615 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NEPIEIGG_00616 1.33e-161 smtA 2.1.1.223 - J ko:K15460 - ko00000,ko01000,ko03016 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NEPIEIGG_00617 5.41e-22 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Psort location Cytoplasmic, score
NEPIEIGG_00618 4.82e-55 - - - - - - - -
NEPIEIGG_00619 1.58e-196 - - - C - - - 4Fe-4S binding domain protein
NEPIEIGG_00620 4.94e-186 - - - S ko:K03453 - ko00000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00621 7.64e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NEPIEIGG_00622 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NEPIEIGG_00623 1.19e-45 - - - S - - - COG NOG33517 non supervised orthologous group
NEPIEIGG_00624 1.66e-252 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_00625 0.0 - 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 polysaccharide deacetylase
NEPIEIGG_00626 0.0 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00627 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00628 0.0 - - - S ko:K21572 - ko00000,ko02000 Pfam:SusD
NEPIEIGG_00629 2.75e-154 - - - S - - - Starch-binding module 26
NEPIEIGG_00631 2.42e-208 - - - C - - - Di-haem oxidoreductase, putative peroxidase
NEPIEIGG_00632 9.43e-138 - - - C - - - Di-haem oxidoreductase, putative peroxidase
NEPIEIGG_00633 1.29e-281 - - - S - - - Psort location CytoplasmicMembrane, score 9.97
NEPIEIGG_00634 0.0 - - - S - - - Psort location OuterMembrane, score
NEPIEIGG_00635 1.35e-102 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_00636 6.1e-40 - - - S - - - COG NOG17292 non supervised orthologous group
NEPIEIGG_00637 0.0 - - - O ko:K06889 - ko00000 COG COG1073 Hydrolases of the alpha beta superfamily
NEPIEIGG_00638 6.73e-217 - - - O - - - SPFH Band 7 PHB domain protein
NEPIEIGG_00639 9.43e-173 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3 C-terminal domain protein
NEPIEIGG_00641 0.0 - - - G - - - cog cog3537
NEPIEIGG_00642 2.62e-287 - - - G - - - Glycosyl hydrolase
NEPIEIGG_00643 1.15e-279 - - - S ko:K21571 - ko00000 SusE outer membrane protein
NEPIEIGG_00644 0.0 - - - F ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_00645 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00646 1.01e-229 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
NEPIEIGG_00647 5.53e-245 - - - L - - - Belongs to the bacterial histone-like protein family
NEPIEIGG_00648 5.18e-55 himA - - L ko:K03530,ko:K04764 - ko00000,ko03032,ko03036,ko03400 COG0776 Bacterial nucleoid DNA-binding protein
NEPIEIGG_00649 0.0 rimO 2.8.4.4 - J ko:K14441 - ko00000,ko01000,ko03009 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
NEPIEIGG_00650 1.6e-220 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NEPIEIGG_00651 5.37e-29 - - - S - - - Domain of unknown function (DUF4295)
NEPIEIGG_00652 3.49e-36 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NEPIEIGG_00653 2.83e-57 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NEPIEIGG_00654 1.97e-101 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NEPIEIGG_00655 8.56e-247 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NEPIEIGG_00656 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_00657 0.0 - - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
NEPIEIGG_00658 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NEPIEIGG_00659 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 bifunctional purine biosynthesis protein PurH
NEPIEIGG_00660 2.63e-241 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein, MreB Mrl family
NEPIEIGG_00661 2.26e-193 - - - K - - - Fic/DOC family
NEPIEIGG_00662 0.0 - - - T - - - PAS fold
NEPIEIGG_00663 8.04e-230 - - - S - - - Fimbrillin-A associated anchor proteins Mfa1 and Mfa2
NEPIEIGG_00664 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00665 0.0 - - - S ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_00667 4.28e-309 - - - S - - - Glycosyl Hydrolase Family 88
NEPIEIGG_00668 0.0 - - - GM ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_00669 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00670 4.95e-98 - - - S - - - Cupin domain protein
NEPIEIGG_00671 3.2e-213 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
NEPIEIGG_00672 1.66e-135 - - - S - - - Protein of unknown function (DUF2961)
NEPIEIGG_00673 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 glycosyl hydrolase, family 3
NEPIEIGG_00674 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Chitobiase/beta-hexosaminidase C-terminal domain
NEPIEIGG_00675 0.0 - 3.2.1.45 GH116 G ko:K17108 ko00511,ko00600,ko01100,map00511,map00600,map01100 ko00000,ko00001,ko01000 Pfam:GBA2_N
NEPIEIGG_00676 2.37e-79 - - - S - - - Protein of unknown function (DUF1232)
NEPIEIGG_00677 5.96e-123 - - - I - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00679 1.54e-124 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEPIEIGG_00680 1.14e-91 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NEPIEIGG_00681 2.01e-185 - - - S - - - Exopolysaccharide biosynthesis protein YbjH
NEPIEIGG_00682 1.06e-231 - - - M ko:K03286 - ko00000,ko02000 OmpA family
NEPIEIGG_00683 1.9e-82 - - - S - - - Domain of unknown function (DUF3869)
NEPIEIGG_00684 2.88e-265 - - - - - - - -
NEPIEIGG_00686 1.29e-233 - - - S - - - COG NOG26583 non supervised orthologous group
NEPIEIGG_00687 1.37e-273 - - - S - - - COG NOG10884 non supervised orthologous group
NEPIEIGG_00688 0.0 aspT - - S ko:K07085 - ko00000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00689 5.36e-143 aspD 4.1.1.12 - E ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 ko00000,ko00001,ko01000 COG COG0436 Aspartate tyrosine aromatic aminotransferase
NEPIEIGG_00690 1.91e-217 aspD 4.1.1.12 - E ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 ko00000,ko00001,ko01000 COG COG0436 Aspartate tyrosine aromatic aminotransferase
NEPIEIGG_00691 2.66e-306 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_00692 0.0 - - - T ko:K02481 - ko00000,ko02022 acetoacetate metabolism regulatory protein AtoC K07714
NEPIEIGG_00693 0.0 - - - MU - - - Psort location OuterMembrane, score
NEPIEIGG_00694 2.84e-115 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_00695 2.91e-144 - - - - - - - -
NEPIEIGG_00696 2.44e-142 - - - - - - - -
NEPIEIGG_00697 5.25e-79 - - - U - - - peptidase
NEPIEIGG_00698 1.54e-28 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
NEPIEIGG_00699 9.03e-217 - - - S - - - Uncharacterised nucleotidyltransferase
NEPIEIGG_00700 1.51e-311 - - - V - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00701 1.05e-226 - - - JM - - - COG NOG09722 non supervised orthologous group
NEPIEIGG_00702 4.59e-135 - - - O - - - SPFH Band 7 PHB domain protein
NEPIEIGG_00704 4.12e-22 - 3.6.4.13, 5.4.99.21 - NU ko:K03578,ko:K06182 - ko00000,ko01000,ko03009 translation initiation factor activity
NEPIEIGG_00707 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NEPIEIGG_00708 1.84e-140 - - - T - - - Response regulator receiver domain protein
NEPIEIGG_00709 4.45e-159 - - - - - - - -
NEPIEIGG_00710 1.15e-199 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
NEPIEIGG_00711 3.96e-89 - - - S - - - COG NOG32209 non supervised orthologous group
NEPIEIGG_00712 6.46e-116 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NEPIEIGG_00713 0.0 fkp - - S - - - GHMP kinase, N-terminal domain protein
NEPIEIGG_00714 6.88e-73 - - - K - - - Transcriptional regulator, MarR family
NEPIEIGG_00715 0.0 cdr - - P - - - Belongs to the sulfur carrier protein TusA family
NEPIEIGG_00716 6.45e-91 - - - S - - - Domain of unknown function (DUF4891)
NEPIEIGG_00717 1.58e-194 - - - S - - - Domain of unknown function (DUF4377)
NEPIEIGG_00718 3.09e-268 yqfO - - C - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NEPIEIGG_00719 1.89e-160 - - - S ko:K07164 - ko00000 Zinc ribbon domain protein
NEPIEIGG_00720 3.75e-288 - - - S - - - non supervised orthologous group
NEPIEIGG_00721 5.69e-189 - - - S - - - COG NOG19137 non supervised orthologous group
NEPIEIGG_00722 0.0 - - - M - - - Efflux transporter, outer membrane factor lipoprotein, NodT family
NEPIEIGG_00723 2.12e-205 - - - M - - - Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEPIEIGG_00725 0.0 - - - O - - - non supervised orthologous group
NEPIEIGG_00726 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00727 2.18e-309 - - - S ko:K21572 - ko00000,ko02000 Pfam:SusD
NEPIEIGG_00728 2.22e-260 fsr - - G ko:K08223 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00729 1.21e-168 - - - V ko:K03543 - ko00000,ko00002,ko02000 Auxiliary transport protein, membrane fusion protein
NEPIEIGG_00730 0.0 - - - EGP - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00731 1.52e-207 - - - K - - - methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family)
NEPIEIGG_00732 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_00733 2.7e-257 kdpD 2.7.13.3 - T ko:K07646 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Psort location Cytoplasmic, score 8.96
NEPIEIGG_00734 1.44e-178 - - - S - - - COG NOG26951 non supervised orthologous group
NEPIEIGG_00735 2.77e-134 kdpC 3.6.3.12 - P ko:K01548 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NEPIEIGG_00736 2.16e-178 kdpB 3.6.3.12 - P ko:K01547 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NEPIEIGG_00737 0.0 - - - S - - - Tetratricopeptide repeat
NEPIEIGG_00738 0.0 msbA - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
NEPIEIGG_00739 2.27e-272 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00740 0.0 - - - S - - - Tat pathway signal sequence domain protein
NEPIEIGG_00741 1.2e-188 - - - G - - - COG NOG16664 non supervised orthologous group
NEPIEIGG_00743 1.22e-116 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NEPIEIGG_00744 3.34e-117 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NEPIEIGG_00745 0.0 - - - S ko:K09704 - ko00000 Conserved protein
NEPIEIGG_00746 2.13e-111 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NEPIEIGG_00747 6.75e-216 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NEPIEIGG_00748 3.3e-70 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00749 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Cell division protein FtsI penicillin-binding protein
NEPIEIGG_00750 2.14e-259 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_00751 2.04e-264 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00752 1.69e-275 - - - U - - - WD40-like Beta Propeller Repeat
NEPIEIGG_00753 1.6e-198 - - - S ko:K07058 - ko00000 Virulence factor BrkB
NEPIEIGG_00754 0.0 amyS 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Alpha-amylase domain
NEPIEIGG_00756 5.46e-73 - - - L - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00759 3.13e-159 - - - S ko:K09797 - ko00000 Protein of unknown function (DUF541)
NEPIEIGG_00760 1.25e-196 ramA_1 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 hydrolase, carbon-nitrogen family
NEPIEIGG_00761 3.67e-136 - - - I - - - Acyltransferase
NEPIEIGG_00762 2.48e-57 - - - S - - - COG NOG23371 non supervised orthologous group
NEPIEIGG_00763 3.23e-289 - - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEPIEIGG_00765 6.04e-27 - - - - - - - -
NEPIEIGG_00766 6.94e-201 - - - G - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00767 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00769 1.36e-244 mdh 1.1.1.37 - C ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the LDH MDH superfamily
NEPIEIGG_00770 8.44e-200 yitL - - S ko:K00243 - ko00000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_00771 6.15e-169 - - - J - - - Domain of unknown function (DUF4476)
NEPIEIGG_00772 2.69e-166 - - - S - - - COG NOG36047 non supervised orthologous group
NEPIEIGG_00773 1.18e-307 - - - MU ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 Psort location OuterMembrane, score 10.00
NEPIEIGG_00774 2.85e-245 - - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEPIEIGG_00775 6.35e-295 macB_3 - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
NEPIEIGG_00776 8.11e-58 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
NEPIEIGG_00777 1.46e-261 - - - S - - - COG NOG25895 non supervised orthologous group
NEPIEIGG_00778 6.65e-180 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00779 4.5e-173 - - - S ko:K06911 - ko00000 Belongs to the pirin family
NEPIEIGG_00780 4.89e-238 ldhA 1.1.1.28 - C ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEPIEIGG_00781 0.0 - - - I ko:K06076 - ko00000,ko02000 COG COG2067 Long-chain fatty acid transport protein
NEPIEIGG_00782 1.26e-308 - - - S - - - COG NOG10142 non supervised orthologous group
NEPIEIGG_00783 5.06e-199 - - - G - - - Glyco_18
NEPIEIGG_00784 3.12e-162 - - - S - - - C terminal of Calcineurin-like phosphoesterase
NEPIEIGG_00785 0.0 araE - - P ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NEPIEIGG_00786 5.06e-312 ce 5.1.3.8 - G ko:K01787 ko00520,map00520 ko00000,ko00001,ko01000 COG COG2942 N-acyl-D-glucosamine 2-epimerase
NEPIEIGG_00787 6.7e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NEPIEIGG_00788 2.44e-269 - - - S - - - Domain of unknown function (DUF4434)
NEPIEIGG_00789 0.0 - 3.1.1.53 - G ko:K05970 - ko00000,ko01000 COG NOG04984 non supervised orthologous group
NEPIEIGG_00792 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00793 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_00794 6.77e-126 - - - G - - - Belongs to the glycosyl hydrolase 2 family
NEPIEIGG_00795 0.0 - - - H - - - Outer membrane protein beta-barrel family
NEPIEIGG_00796 4.1e-111 - - - S - - - COG NOG30135 non supervised orthologous group
NEPIEIGG_00797 1.7e-84 - - - KT - - - Transcriptional regulatory protein, C terminal
NEPIEIGG_00798 8.67e-90 - - - KT - - - Transcriptional regulatory protein, C terminal
NEPIEIGG_00799 4.82e-55 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NEPIEIGG_00800 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NEPIEIGG_00801 1.19e-145 - - - C - - - Nitroreductase family
NEPIEIGG_00802 4.91e-175 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NEPIEIGG_00803 2.57e-114 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NEPIEIGG_00804 0.0 - 3.6.4.13 - L ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Belongs to the DEAD box helicase family
NEPIEIGG_00805 2.22e-256 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_00806 3.32e-147 - - - S - - - Domain of unknown function (DUF5043)
NEPIEIGG_00807 3.74e-148 - - - S - - - Domain of unknown function (DUF5043)
NEPIEIGG_00808 0.0 - - - - - - - -
NEPIEIGG_00809 7.99e-225 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG COG0524 Sugar kinases, ribokinase family
NEPIEIGG_00810 7.6e-64 kdsD 5.3.1.13 - M ko:K06041 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 sugar phosphate isomerase involved in capsule formation
NEPIEIGG_00811 0.0 - - - KT - - - COG NOG11230 non supervised orthologous group
NEPIEIGG_00812 6.72e-152 - - - C - - - WbqC-like protein
NEPIEIGG_00813 7.15e-229 lepB_1 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NEPIEIGG_00814 0.0 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 signal peptidase i
NEPIEIGG_00815 2.22e-183 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the DapB family
NEPIEIGG_00817 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NEPIEIGG_00818 5.44e-127 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
NEPIEIGG_00819 1.23e-253 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
NEPIEIGG_00820 0.0 thrA 1.1.1.3, 2.7.2.4 - E ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NEPIEIGG_00821 2.85e-307 - 5.4.2.12 - G ko:K15635 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 homoserine kinase
NEPIEIGG_00823 1.31e-285 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NEPIEIGG_00825 1.34e-186 - - - - - - - -
NEPIEIGG_00826 0.0 - - - S - - - SusD family
NEPIEIGG_00827 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00828 0.0 cobJ 5.4.99.60, 5.4.99.61 - H ko:K06042 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 COG1010 Precorrin-3B methylase
NEPIEIGG_00829 2.19e-217 - - - K - - - transcriptional regulator (AraC family)
NEPIEIGG_00830 7.75e-158 cbiK 4.99.1.3 - H ko:K02190 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 CbiX
NEPIEIGG_00831 1.19e-15 cbiK 4.99.1.3 - H ko:K02190 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 CbiX
NEPIEIGG_00832 0.0 - - - P ko:K16089 - ko00000,ko02000 COG4771 Outer membrane receptor for ferrienterochelin and colicins
NEPIEIGG_00833 0.0 - - - S - - - domain protein
NEPIEIGG_00834 3.01e-88 - 4.99.1.3 - H ko:K02190 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 COG4822 Cobalamin biosynthesis protein CbiK Co2 chelatase
NEPIEIGG_00835 0.0 - 3.1.1.53 - G ko:K05970 - ko00000,ko01000 COG NOG04984 non supervised orthologous group
NEPIEIGG_00837 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit
NEPIEIGG_00838 7.14e-195 - - - S - - - COG NOG19130 non supervised orthologous group
NEPIEIGG_00839 4.6e-256 - - - M - - - peptidase S41
NEPIEIGG_00840 0.0 - - - - - - - -
NEPIEIGG_00841 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00842 0.0 - - - GM ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_00843 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00844 0.0 - - - K ko:K21572 - ko00000,ko02000 Pfam:SusD
NEPIEIGG_00845 3.39e-148 - - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
NEPIEIGG_00846 1.34e-164 yjjG - - S ko:K07025 - ko00000 HAD hydrolase, TIGR02254 family
NEPIEIGG_00847 5.34e-155 - - - S - - - Transposase
NEPIEIGG_00848 9.06e-159 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NEPIEIGG_00849 4.64e-105 - - - S - - - COG NOG23390 non supervised orthologous group
NEPIEIGG_00851 0.0 - - - T - - - Tetratricopeptide repeat protein
NEPIEIGG_00852 5.71e-96 - - - T - - - Tetratricopeptide repeat protein
NEPIEIGG_00853 1.89e-177 - - - T ko:K02477 - ko00000,ko02022 COG3279 Response regulator of the LytR AlgR family
NEPIEIGG_00854 2.32e-75 - - - S - - - COG NOG30654 non supervised orthologous group
NEPIEIGG_00855 5.5e-286 - - - S - - - COG NOG27441 non supervised orthologous group
NEPIEIGG_00856 3.86e-51 - - - P - - - TonB-dependent receptor
NEPIEIGG_00857 0.0 - - - P - - - TonB-dependent receptor
NEPIEIGG_00858 4.03e-81 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NEPIEIGG_00859 5.24e-128 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NEPIEIGG_00860 2.13e-36 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NEPIEIGG_00861 6.96e-64 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NEPIEIGG_00862 1.34e-314 paaK 6.2.1.30 - H ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 ko00000,ko00001,ko01000 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NEPIEIGG_00863 1.17e-132 iorB 1.2.7.8 - C ko:K00180 - br01601,ko00000,ko01000 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
NEPIEIGG_00864 0.0 iorA 1.2.7.8 - C ko:K00179 - br01601,ko00000,ko01000 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
NEPIEIGG_00865 2.48e-252 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NEPIEIGG_00866 1.04e-94 tolB3 - - U - - - WD40-like Beta Propeller Repeat
NEPIEIGG_00868 7.82e-214 - - - L - - - Belongs to the 'phage' integrase family
NEPIEIGG_00869 0.0 - - - P - - - Psort location OuterMembrane, score
NEPIEIGG_00870 7.52e-263 - - - S - - - Endonuclease Exonuclease phosphatase family protein
NEPIEIGG_00871 2.52e-203 - - - O - - - COG NOG23400 non supervised orthologous group
NEPIEIGG_00872 0.0 - 5.2.1.8 - M ko:K03771 - ko00000,ko01000,ko03110 COG COG0760 Parvulin-like peptidyl-prolyl isomerase
NEPIEIGG_00873 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NEPIEIGG_00874 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NEPIEIGG_00875 5.83e-250 - - - S ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_00877 1.07e-285 - 3.2.1.78 GH26 G ko:K01218,ko:K19355 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
NEPIEIGG_00878 0.0 - - - G - - - Belongs to the glycosyl hydrolase 2 family
NEPIEIGG_00879 2.59e-18 - - - - - - - -
NEPIEIGG_00880 1.65e-77 mutB 5.4.99.2 - I ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_00881 7.94e-117 - - - M - - - Protein of unknown function (DUF3575)
NEPIEIGG_00882 2.42e-190 - - - S - - - COG NOG26135 non supervised orthologous group
NEPIEIGG_00883 1e-173 - - - S - - - Fimbrillin-like
NEPIEIGG_00884 0.0 - - - - - - - -
NEPIEIGG_00885 4.56e-57 - - - M - - - Polymer-forming cytoskeletal
NEPIEIGG_00887 1.2e-207 - - - EG - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00888 2.16e-201 - - - P - - - ATP-binding protein involved in virulence
NEPIEIGG_00889 3.98e-175 - - - P - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00890 4.55e-48 - - - P - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00891 9.15e-301 ybdG_2 - - M ko:K16053 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
NEPIEIGG_00892 3.4e-93 - - - L - - - regulation of translation
NEPIEIGG_00893 2.59e-277 - - - N - - - COG NOG06100 non supervised orthologous group
NEPIEIGG_00894 2.9e-175 - - - M - - - TonB-dependent receptor
NEPIEIGG_00895 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 glycosyl hydrolase, family 3
NEPIEIGG_00896 8.64e-276 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG2706 3-carboxymuconate cyclase
NEPIEIGG_00897 4.55e-245 - - - S - - - COG NOG25792 non supervised orthologous group
NEPIEIGG_00898 4.66e-84 pqqD - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00899 0.0 - - - G - - - Transporter, major facilitator family protein
NEPIEIGG_00900 2.47e-61 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
NEPIEIGG_00901 2.41e-192 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NEPIEIGG_00902 3.61e-289 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
NEPIEIGG_00903 0.0 - - - A - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00904 2.61e-245 purH2 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
NEPIEIGG_00905 2.14e-29 purH2 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
NEPIEIGG_00907 1.28e-82 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NEPIEIGG_00908 0.0 - - - GM ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_00909 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_00910 1.19e-17 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00911 6.28e-304 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00912 0.0 - - - D - - - Domain of unknown function
NEPIEIGG_00913 6.39e-261 - - - D - - - Domain of unknown function
NEPIEIGG_00914 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NEPIEIGG_00915 2.83e-109 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEPIEIGG_00916 3.85e-197 - - - S - - - P-loop ATPase and inactivated derivatives
NEPIEIGG_00917 0.0 - - - S - - - P-loop ATPase and inactivated derivatives
NEPIEIGG_00918 2.57e-127 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_00919 2.35e-136 rnd - - L - - - 3'-5' exonuclease
NEPIEIGG_00920 7.34e-293 rlmI 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 SAM-dependent
NEPIEIGG_00921 1.79e-114 - - - K - - - transcriptional regulator, LuxR family
NEPIEIGG_00922 5.89e-10 maa 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_00923 5.47e-140 - - - S ko:K09702 - ko00000 Protein of unknown function (DUF1349)
NEPIEIGG_00924 6.77e-20 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_00925 1.62e-112 mdh 1.1.1.37 - C ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible oxidation of malate to oxaloacetate
NEPIEIGG_00926 0.0 - - - M - - - Tricorn protease homolog
NEPIEIGG_00927 0.0 - - - G - - - unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NEPIEIGG_00928 1.02e-152 - - - K ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_00929 3.51e-48 - - - S ko:K21572 - ko00000,ko02000 PFAM RagB SusD domain protein
NEPIEIGG_00930 4.05e-83 - - - S - - - Metallo-beta-lactamase superfamily
NEPIEIGG_00931 8.55e-24 - - - S - - - Metallo-beta-lactamase superfamily
NEPIEIGG_00932 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_00935 4.04e-124 yihY - - S ko:K07058 - ko00000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00936 1.75e-07 - - - C - - - Nitroreductase family
NEPIEIGG_00937 1.21e-142 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 COG0307 Riboflavin synthase alpha chain
NEPIEIGG_00938 1.43e-154 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NEPIEIGG_00939 4.64e-173 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEPIEIGG_00940 7.99e-193 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00941 2.36e-269 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NEPIEIGG_00942 1.01e-184 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 COG0226 ABC-type phosphate transport system, periplasmic component
NEPIEIGG_00944 8.42e-270 fcl 1.1.1.271 - GM ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
NEPIEIGG_00945 6.2e-265 gmd 4.2.1.47 - M ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NEPIEIGG_00946 7.67e-256 sstT - - U - - - Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NEPIEIGG_00947 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NEPIEIGG_00949 6.45e-91 - - - S - - - Polyketide cyclase
NEPIEIGG_00950 5.07e-150 pyrE 2.4.2.10, 4.1.1.23 - F ko:K00762,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NEPIEIGG_00951 1.09e-109 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
NEPIEIGG_00952 5.86e-191 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NEPIEIGG_00953 3.25e-252 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NEPIEIGG_00954 0.0 - - - G - - - COG NOG27066 non supervised orthologous group
NEPIEIGG_00955 5.67e-179 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NEPIEIGG_00956 1.86e-271 nanM - - S - - - COG NOG23382 non supervised orthologous group
NEPIEIGG_00957 1.09e-72 - - - S - - - Domain of unknown function (DUF4907)
NEPIEIGG_00958 1.17e-236 - - - - - - - -
NEPIEIGG_00959 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)
NEPIEIGG_00960 2.5e-99 - - - S - - - COG NOG29214 non supervised orthologous group
NEPIEIGG_00961 2.99e-173 - - - E - - - Peptidase family M1 domain
NEPIEIGG_00962 1.73e-161 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_00963 1.16e-129 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NEPIEIGG_00964 6.22e-97 - - - M - - - COG COG3209 Rhs family protein
NEPIEIGG_00965 9.37e-79 - - - M - - - COG COG3209 Rhs family protein
NEPIEIGG_00966 7.62e-307 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NEPIEIGG_00967 3.15e-151 - - - S - - - PD-(D/E)XK nuclease family transposase
NEPIEIGG_00968 1.3e-76 - 3.1.3.102, 3.1.3.104 - S ko:K07025,ko:K20862 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 HAD-hyrolase-like
NEPIEIGG_00969 1.49e-28 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00971 2.99e-316 - - - O - - - protein conserved in bacteria
NEPIEIGG_00972 1.31e-30 - - - S - - - COG NOG19133 non supervised orthologous group
NEPIEIGG_00973 3.59e-258 - - - S - - - COG NOG19133 non supervised orthologous group
NEPIEIGG_00974 5.32e-295 - - - E - - - Glycosyl Hydrolase Family 88
NEPIEIGG_00975 0.0 - - - G - - - hydrolase, family 43
NEPIEIGG_00976 0.0 dpp 3.4.14.5 - EU ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase, S9A B C family, catalytic domain protein
NEPIEIGG_00977 1.26e-213 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NEPIEIGG_00978 1.66e-267 - - - I - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_00979 1.98e-167 rsmI_1 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Psort location Cytoplasmic, score 8.96
NEPIEIGG_00980 3.72e-202 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NEPIEIGG_00982 4.87e-155 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
NEPIEIGG_00983 1.09e-220 - 4.1.3.3, 4.2.1.41, 4.3.3.7 - EM ko:K01639,ko:K01707,ko:K01714 ko00053,ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00053,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the DapA family
NEPIEIGG_00984 0.0 - - - E ko:K03307 - ko00000 alkaline phosphatase synthesis sensor protein phoR K07636
NEPIEIGG_00985 5.19e-170 - - - K - - - Transcriptional regulator, GntR family
NEPIEIGG_00987 9.87e-122 cobU 2.7.1.156, 2.7.7.62 - H ko:K02231 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 bifunctional cobalamin biosynthesis protein
NEPIEIGG_00988 6.82e-251 cobT 2.4.2.21 - F ko:K00768 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
NEPIEIGG_00989 2.57e-109 - - - K - - - Helix-turn-helix domain
NEPIEIGG_00990 6.95e-197 - - - H - - - Methyltransferase domain
NEPIEIGG_00991 0.0 - - - K ko:K03088 - ko00000,ko03021 Outer membrane protein beta-barrel domain
NEPIEIGG_00992 5.83e-100 - - - P ko:K03711 - ko00000,ko03000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_00993 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_00995 3.57e-141 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NEPIEIGG_00996 0.0 - - - S ko:K07014 - ko00000 Domain of unknown function (DUF3413)
NEPIEIGG_00997 1.61e-250 pdxB 1.1.1.290 - H ko:K03473 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate
NEPIEIGG_00998 1.95e-45 - - - - - - - -
NEPIEIGG_00999 1.54e-24 - - - - - - - -
NEPIEIGG_01001 3.78e-142 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEPIEIGG_01002 8.64e-38 - - - M ko:K07271 - ko00000,ko01000 COG COG3475 LPS biosynthesis protein
NEPIEIGG_01003 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NEPIEIGG_01004 1.35e-291 - - - M - - - COG NOG26016 non supervised orthologous group
NEPIEIGG_01005 2.31e-286 - - - M - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01011 1.61e-132 - - - - - - - -
NEPIEIGG_01012 2.68e-17 - - - - - - - -
NEPIEIGG_01013 1.23e-29 - - - K - - - Helix-turn-helix domain
NEPIEIGG_01014 1.88e-62 - - - S - - - Helix-turn-helix domain
NEPIEIGG_01015 1.97e-119 - - - C - - - Flavodoxin
NEPIEIGG_01016 2.11e-273 - - - S ko:K06889 - ko00000 of the alpha beta superfamily
NEPIEIGG_01017 2.42e-263 - - - S - - - COG NOG15865 non supervised orthologous group
NEPIEIGG_01018 5.29e-262 - - - S - - - NPCBM-associated, NEW3 domain of alpha-galactosidase
NEPIEIGG_01019 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NEPIEIGG_01020 6.55e-65 - - - T - - - COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NEPIEIGG_01022 2.34e-75 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01023 7.79e-220 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01024 4.45e-100 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NEPIEIGG_01025 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
NEPIEIGG_01026 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
NEPIEIGG_01027 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 COG NOG04002 non supervised orthologous group
NEPIEIGG_01028 3.13e-226 - - - L - - - Belongs to the 'phage' integrase family
NEPIEIGG_01029 2.18e-270 - - - S - - - ATPase domain predominantly from Archaea
NEPIEIGG_01030 1.27e-223 - 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 HipA-like C-terminal domain
NEPIEIGG_01031 2.04e-74 - 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 domain protein
NEPIEIGG_01032 6.85e-33 - - - K - - - transcriptional regulator, y4mF family
NEPIEIGG_01033 2.47e-275 - - - D - - - nuclear chromosome segregation
NEPIEIGG_01034 9.87e-263 buk 2.7.2.7 - H ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
NEPIEIGG_01035 4.1e-221 - 2.3.1.19, 2.3.1.8 - C ko:K00625,ko:K00634 ko00430,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00650,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_01036 3.42e-232 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
NEPIEIGG_01037 1.31e-244 ywaD - - S - - - glutaminyl-peptide cyclotransferase (glutaminyl cyclase) K00683
NEPIEIGG_01038 4.14e-94 sufE - - S ko:K02426 - ko00000 COG2166 SufE protein probably involved in Fe-S center assembly
NEPIEIGG_01039 8.83e-39 - - - K ko:K07727 - ko00000,ko03000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01040 3.41e-144 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01041 1.83e-78 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01042 0.0 - - - G - - - Belongs to the glycosyl hydrolase 2 family
NEPIEIGG_01043 7.2e-141 - - - G - - - Belongs to the glycosyl hydrolase 43 family
NEPIEIGG_01044 3.86e-285 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
NEPIEIGG_01046 1e-75 - - - P - - - TonB dependent receptor
NEPIEIGG_01047 2.34e-32 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEPIEIGG_01048 8.29e-55 - - - - - - - -
NEPIEIGG_01049 4.56e-120 fldA - - C ko:K03839 - ko00000 Low-potential electron donor to a number of redox enzymes
NEPIEIGG_01050 0.0 glgP 2.4.1.1, 2.4.1.11, 2.4.1.8 GH65,GT3,GT35 G ko:K00688,ko:K00691,ko:K16153 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000,ko01003 COG0058 Glucan phosphorylase
NEPIEIGG_01051 0.0 - 2.4.1.11 GT3 G ko:K00693 ko00500,ko01100,ko04151,ko04152,ko04910,ko04922,ko04931,map00500,map01100,map04151,map04152,map04910,map04922,map04931 ko00000,ko00001,ko01000,ko01003 Starch synthase
NEPIEIGG_01053 7.76e-89 ntpK - - C ko:K02124 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG COG0636 F0F1-type ATP synthase, subunit c Archaeal vacuolar-type H -ATPase, subunit K
NEPIEIGG_01054 1.69e-51 - - - C ko:K02123 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Belongs to the V-ATPase 116 kDa subunit family
NEPIEIGG_01055 1.7e-141 - - - L - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01056 1.97e-34 - - - - - - - -
NEPIEIGG_01057 0.0 - - - N - - - COG NOG14601 non supervised orthologous group
NEPIEIGG_01059 1.77e-78 norM - - V ko:K03327 - ko00000,ko02000 MATE efflux family protein
NEPIEIGG_01060 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_01065 2.58e-254 - 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Serine/threonine phosphatases, family 2C, catalytic domain
NEPIEIGG_01066 0.0 - - - T - - - Forkhead associated domain
NEPIEIGG_01067 0.0 - 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
NEPIEIGG_01068 5.17e-145 - - - S - - - Double zinc ribbon
NEPIEIGG_01069 6.4e-81 - - - S - - - Putative binding domain, N-terminal
NEPIEIGG_01072 5.05e-279 ydiI 3.1.2.28 - Q ko:K19222 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01073 5.48e-165 - - - S ko:K07000 - ko00000 Uncharacterised protein family (UPF0227)
NEPIEIGG_01074 2.96e-304 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NEPIEIGG_01075 5.09e-200 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NEPIEIGG_01076 4.19e-240 pfkA 2.7.1.11, 2.7.1.90 - F ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NEPIEIGG_01077 4.4e-184 - - - H - - - GH3 auxin-responsive promoter
NEPIEIGG_01078 1.03e-148 - - - H - - - GH3 auxin-responsive promoter
NEPIEIGG_01079 1.32e-215 - - - M - - - COG NOG19097 non supervised orthologous group
NEPIEIGG_01080 2.01e-145 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NEPIEIGG_01081 6.86e-262 - - - S - - - DNA-binding protein with the Helix-hairpin-helix motif
NEPIEIGG_01082 4.51e-189 - - - L - - - DNA metabolism protein
NEPIEIGG_01083 1.8e-144 - - - S ko:K07507 - ko00000,ko02000 Mg2 transporter-C family protein
NEPIEIGG_01084 3.6e-241 mltD_2 - - M - - - Transglycosylase SLT domain protein
NEPIEIGG_01085 1.23e-169 - - - S - - - Oxidoreductase, short chain dehydrogenase reductase family protein
NEPIEIGG_01086 3.46e-95 yjbQ - - S - - - Secondary thiamine-phosphate synthase enzyme
NEPIEIGG_01087 0.0 - - - T - - - Psort location CytoplasmicMembrane, score 7.88
NEPIEIGG_01089 1.61e-248 - - - S ko:K09955 - ko00000 protein conserved in bacteria
NEPIEIGG_01090 5.95e-205 - - - S ko:K09955 - ko00000 protein conserved in bacteria
NEPIEIGG_01091 0.0 - - - G - - - Carbohydrate binding domain protein
NEPIEIGG_01092 4.25e-179 - - - G - - - COG NOG26813 non supervised orthologous group
NEPIEIGG_01093 7.51e-188 - - - E - - - GDSL-like Lipase/Acylhydrolase
NEPIEIGG_01094 1.4e-105 nodN - - I - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01095 9.38e-46 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01096 1.75e-84 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01097 1.39e-54 - - - S - - - COG NOG23408 non supervised orthologous group
NEPIEIGG_01098 7.82e-111 yvbK 2.3.1.82 - K ko:K18815 - br01600,ko00000,ko01000,ko01504 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01099 2.55e-287 - - - T - - - histidine kinase DNA gyrase B
NEPIEIGG_01100 1.09e-105 - - - S - - - COG NOG29454 non supervised orthologous group
NEPIEIGG_01101 4.72e-76 ogt 2.1.1.63 - L ko:K00567,ko:K07443 - ko00000,ko01000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
NEPIEIGG_01103 0.0 susC - - P ko:K21573 - ko00000,ko02000 TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_01104 0.0 susD - - M ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_01105 1.79e-287 - - - S ko:K21571 - ko00000 Outer membrane protein SusF_SusE
NEPIEIGG_01106 0.0 - - - S ko:K21571 - ko00000 Domain of unknown function (DUF5115)
NEPIEIGG_01107 4.33e-113 lolE - - M ko:K09808,ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4591 ABC-type transport system, involved in lipoprotein release, permease component
NEPIEIGG_01108 2.43e-151 mdmC 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_01109 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase
NEPIEIGG_01110 6.15e-95 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
NEPIEIGG_01111 3.82e-227 xerC - - D ko:K04763 - ko00000,ko03036 Tyrosine recombinase XerC
NEPIEIGG_01112 0.0 - - - S - - - Tetratricopeptide repeat protein
NEPIEIGG_01113 1.64e-35 - - - M ko:K07257 - ko00000 Cytidylyltransferase
NEPIEIGG_01114 1.4e-87 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NEPIEIGG_01115 4.67e-66 - - - C - - - Aldo/keto reductase family
NEPIEIGG_01116 4.78e-295 pseC - - E - - - Belongs to the DegT DnrJ EryC1 family
NEPIEIGG_01117 1.81e-116 pseB 4.2.1.115 - M ko:K15894 ko00520,map00520 ko00000,ko00001,ko01000 Male sterility protein
NEPIEIGG_01118 2.46e-90 pseB 4.2.1.115 - M ko:K15894 ko00520,map00520 ko00000,ko00001,ko01000 Male sterility protein
NEPIEIGG_01119 6.05e-113 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01120 8.59e-121 - - - K - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01121 6.16e-49 - - - KT ko:K03973 - ko00000,ko02048,ko03000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01122 1.56e-155 exbB - - U ko:K03561 - ko00000,ko02000 MotA TolQ ExbB proton channel family
NEPIEIGG_01123 2.74e-95 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01124 7.36e-117 - - - U - - - COG NOG14449 non supervised orthologous group
NEPIEIGG_01125 1.52e-88 - - - U ko:K03559 - ko00000,ko02000 COG NOG14448 non supervised orthologous group
NEPIEIGG_01126 4.86e-129 - - - K - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01127 0.0 - - - S - - - IgA Peptidase M64
NEPIEIGG_01128 8.67e-111 asnC - - K ko:K03718 - ko00000,ko03000 transcriptional regulator, AsnC family
NEPIEIGG_01129 1.01e-111 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NEPIEIGG_01130 2.84e-200 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NEPIEIGG_01131 1.09e-224 - - - S - - - COG NOG31846 non supervised orthologous group
NEPIEIGG_01132 6.28e-242 - - - S - - - COG NOG26135 non supervised orthologous group
NEPIEIGG_01133 4.55e-155 - - - M - - - COG NOG24980 non supervised orthologous group
NEPIEIGG_01134 1.45e-190 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 COG0584 Glycerophosphoryl diester phosphodiesterase
NEPIEIGG_01135 4.75e-267 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
NEPIEIGG_01136 2.3e-98 - - - S ko:K07107 - ko00000,ko01000 acyl-CoA thioester hydrolase, YbgC YbaW family
NEPIEIGG_01137 2.88e-175 prtC - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01138 8.35e-129 eam 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 KamA family
NEPIEIGG_01139 1.26e-142 mug - - L - - - COG3663 G T U mismatch-specific DNA glycosylase
NEPIEIGG_01141 3.1e-152 - - - L - - - Phage integrase family
NEPIEIGG_01142 2.29e-37 - - - - - - - -
NEPIEIGG_01143 2.66e-24 - - - - - - - -
NEPIEIGG_01144 1.05e-98 - - - - - - - -
NEPIEIGG_01145 1.5e-114 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG NOG32858 non supervised orthologous group
NEPIEIGG_01146 6.89e-92 - - - - - - - -
NEPIEIGG_01147 3.37e-118 - - - L - - - COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
NEPIEIGG_01148 2.35e-56 - - - L - - - COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
NEPIEIGG_01149 8.44e-71 - - - S - - - Plasmid stabilization system
NEPIEIGG_01150 2.14e-29 - - - - - - - -
NEPIEIGG_01151 9.82e-220 - - - EG - - - COG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NEPIEIGG_01152 7.47e-163 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiamine diphosphokinase
NEPIEIGG_01153 2.68e-136 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NEPIEIGG_01154 0.0 - - - P ko:K02014 - ko00000,ko02000 COG COG1629 Outer membrane receptor proteins, mostly Fe transport
NEPIEIGG_01156 1.91e-55 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01157 1.39e-177 yebC - - K - - - Transcriptional regulatory protein
NEPIEIGG_01158 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Psort location Cytoplasmic, score
NEPIEIGG_01159 8.9e-11 - - - - - - - -
NEPIEIGG_01160 3.75e-109 - - - L - - - DNA-binding protein
NEPIEIGG_01161 1.2e-139 pglE - - E - - - Belongs to the DegT DnrJ EryC1 family
NEPIEIGG_01162 3.81e-286 gluP - - G ko:K02429 - ko00000,ko02000 Transporter, major facilitator family protein
NEPIEIGG_01163 0.0 - 3.2.1.14 GH18 G ko:K01183,ko:K09992 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 18 family
NEPIEIGG_01165 4.08e-64 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_01166 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_01167 5.22e-145 - - - S - - - Phage-related minor tail protein
NEPIEIGG_01168 1.42e-34 - - - - - - - -
NEPIEIGG_01170 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NEPIEIGG_01171 1.19e-117 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor
NEPIEIGG_01173 4.29e-155 - - - PT - - - Sigma factor regulatory protein, FecR PupR family
NEPIEIGG_01174 0.0 - - - S - - - COG NOG06390 non supervised orthologous group
NEPIEIGG_01175 2.34e-66 - - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Psort location Cytoplasmic, score
NEPIEIGG_01176 1.18e-98 - - - O - - - Thioredoxin
NEPIEIGG_01177 1.08e-212 - 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01178 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
NEPIEIGG_01179 1.16e-195 - - - S - - - COG NOG25193 non supervised orthologous group
NEPIEIGG_01180 3.51e-53 trpC 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
NEPIEIGG_01181 1.25e-152 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
NEPIEIGG_01182 1.69e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NEPIEIGG_01183 2.8e-255 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
NEPIEIGG_01184 0.0 - - - S - - - Domain of unknown function (DUF4842)
NEPIEIGG_01186 0.0 - - - M - - - Cellulase N-terminal ig-like domain
NEPIEIGG_01188 0.0 - - - S - - - Susd and RagB outer membrane lipoprotein
NEPIEIGG_01189 2.22e-251 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_01190 9.98e-175 dacB 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
NEPIEIGG_01191 2.9e-224 - - - K - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01192 1.99e-263 - - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEPIEIGG_01194 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_01195 9.73e-155 yhhQ - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NEPIEIGG_01196 5.24e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NEPIEIGG_01197 5.68e-113 queF 1.7.1.13 - H ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NEPIEIGG_01198 5.86e-273 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
NEPIEIGG_01199 0.0 - - - S - - - Glycosyl Hydrolase Family 88
NEPIEIGG_01200 0.0 lacZ_2 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
NEPIEIGG_01203 0.0 - - - T - - - PAS domain S-box protein
NEPIEIGG_01204 0.0 nuoN 1.6.5.3 - C ko:K00343 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NEPIEIGG_01205 0.0 - - - S - - - PQQ enzyme repeat
NEPIEIGG_01206 0.0 - - - M - - - TonB-dependent receptor
NEPIEIGG_01207 5.65e-203 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01208 0.0 pepX2 3.4.14.5 - E ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase, S9A B C family, catalytic domain protein
NEPIEIGG_01209 8.33e-317 rlmL - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NEPIEIGG_01210 2.1e-215 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 9.97
NEPIEIGG_01211 3.72e-142 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
NEPIEIGG_01212 7.33e-135 - - - T - - - COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NEPIEIGG_01213 3.49e-23 - - - - - - - -
NEPIEIGG_01214 0.0 - - - S - - - Large extracellular alpha-helical protein
NEPIEIGG_01215 2.62e-287 - - - S - - - Domain of unknown function (DUF4249)
NEPIEIGG_01216 1.16e-175 - - - S - - - Domain of unknown function (DUF4249)
NEPIEIGG_01217 1.74e-67 - - - S - - - COG NOG27363 non supervised orthologous group
NEPIEIGG_01218 9.77e-152 narL - - K - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEPIEIGG_01219 1.3e-264 trmU 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NEPIEIGG_01220 8.28e-310 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_01221 0.0 - - - M - - - peptidase S41
NEPIEIGG_01222 2.6e-215 - - - S - - - COG NOG30864 non supervised orthologous group
NEPIEIGG_01224 3.42e-157 - - - S - - - B3 4 domain protein
NEPIEIGG_01225 3.08e-205 - - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
NEPIEIGG_01226 6.47e-287 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NEPIEIGG_01227 1.08e-131 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NEPIEIGG_01228 2.91e-121 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NEPIEIGG_01230 1.71e-59 nagC 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_01231 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_01232 0.0 - - - S ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_01234 1.13e-309 ykfC - - M - - - NlpC P60 family protein
NEPIEIGG_01235 4.03e-284 ykfB 5.1.1.20, 5.1.1.3 - M ko:K01776,ko:K19802 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the mandelate racemase muconate lactonizing enzyme family
NEPIEIGG_01236 3.8e-39 - - - E - - - Transglutaminase-like
NEPIEIGG_01237 9.66e-284 - - - E - - - Transglutaminase-like
NEPIEIGG_01238 1.23e-143 - - - V - - - COG0534 Na -driven multidrug efflux pump
NEPIEIGG_01239 5.03e-75 - - - V - - - COG0534 Na -driven multidrug efflux pump
NEPIEIGG_01240 2.62e-125 - - - T - - - - catabolite gene activator and regulatory subunit of cAMP-dependent protein
NEPIEIGG_01241 7.4e-182 - - - O - - - COG COG3187 Heat shock protein
NEPIEIGG_01242 5.25e-304 LYS1 1.5.1.7 - E ko:K00290 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 COG1748 Saccharopine dehydrogenase and related
NEPIEIGG_01243 5.77e-102 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 bacterioferritin comigratory protein
NEPIEIGG_01244 4.89e-233 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NEPIEIGG_01245 3.1e-96 - - - S - - - Domain of unknown function (DUF4252)
NEPIEIGG_01246 1.82e-154 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_01247 0.0 - - - S - - - Domain of unknown function (DUF4434)
NEPIEIGG_01248 4.66e-233 glcU - - G ko:K05340 - ko00000,ko02000 COG NOG04879 non supervised orthologous group
NEPIEIGG_01249 0.0 - - - O - - - COG NOG08360 non supervised orthologous group
NEPIEIGG_01250 2e-184 - - - S - - - Ser Thr phosphatase family protein
NEPIEIGG_01251 2.06e-166 - - - K ko:K21572 - ko00000,ko02000 PFAM RagB SusD
NEPIEIGG_01252 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase C-terminal domain
NEPIEIGG_01253 1.41e-211 - - - E - - - GDSL-like Lipase/Acylhydrolase
NEPIEIGG_01256 6.94e-261 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 hydrolase, family 43
NEPIEIGG_01257 3.47e-246 - - - G - - - Belongs to the glycosyl hydrolase 43 family
NEPIEIGG_01258 4.74e-244 - - - G - - - Belongs to the glycosyl hydrolase 43 family
NEPIEIGG_01259 2.16e-115 - - - G - - - Glycosyl hydrolases family 43
NEPIEIGG_01260 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NEPIEIGG_01261 2.41e-155 - - - - - - - -
NEPIEIGG_01262 0.0 recD2_2 3.1.11.5 - L ko:K01144 - ko00000,ko01000 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
NEPIEIGG_01263 1.39e-164 - - - S - - - COG NOG19144 non supervised orthologous group
NEPIEIGG_01265 1.55e-149 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01266 1.93e-122 - - - S - - - COG NOG28211 non supervised orthologous group
NEPIEIGG_01267 1.2e-170 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01268 0.0 - 4.2.2.20, 4.2.2.21 - H ko:K08961 - ko00000,ko01000 Chondroitin sulfate ABC lyase
NEPIEIGG_01269 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NEPIEIGG_01270 1.68e-90 - - - S - - - COG NOG29882 non supervised orthologous group
NEPIEIGG_01271 6.7e-146 - - - S ko:K06950 - ko00000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01273 0.0 - - - M - - - Glycosyl hydrolases family 43
NEPIEIGG_01274 1.31e-47 - - - H - - - COG4206 Outer membrane cobalamin receptor protein
NEPIEIGG_01275 2.21e-204 - - - S - - - amine dehydrogenase activity
NEPIEIGG_01276 1.02e-255 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NEPIEIGG_01277 8.3e-230 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEPIEIGG_01278 3.81e-08 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01279 1.59e-303 - - - S - - - CarboxypepD_reg-like domain
NEPIEIGG_01280 1.61e-125 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor
NEPIEIGG_01281 8.14e-116 spmA - - S ko:K06373 - ko00000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01282 7.82e-97 ybeY - - S - - - Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NEPIEIGG_01283 4.75e-129 - - - - - - - -
NEPIEIGG_01285 1.07e-170 - - - S - - - pyrogenic exotoxin B
NEPIEIGG_01286 6.81e-117 - - - S - - - pyrogenic exotoxin B
NEPIEIGG_01287 3.38e-278 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
NEPIEIGG_01288 5.02e-222 - - - O - - - COG NOG25094 non supervised orthologous group
NEPIEIGG_01289 6.51e-215 - - - G - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01290 0.0 hcp 1.7.99.1 - C ko:K05601 ko00910,map00910 ko00000,ko00001,ko01000 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O
NEPIEIGG_01291 6.37e-144 - - - K - - - - catabolite gene activator and regulatory subunit of cAMP-dependent protein
NEPIEIGG_01292 5.42e-158 - - - K - - - COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NEPIEIGG_01293 2.35e-248 - - - M - - - COG NOG37029 non supervised orthologous group
NEPIEIGG_01294 3.01e-173 glnS 6.1.1.18 - J ko:K01886 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glutamine--tRNA ligase
NEPIEIGG_01295 7.67e-309 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01296 1.07e-151 dedA - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01297 2.45e-114 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NEPIEIGG_01298 1.92e-134 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01299 2.16e-130 - - - L - - - COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
NEPIEIGG_01300 9.27e-195 pglE - - E - - - Belongs to the DegT DnrJ EryC1 family
NEPIEIGG_01302 0.0 - - - P - - - COG COG3119 Arylsulfatase A and related enzymes
NEPIEIGG_01303 1.9e-219 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_01304 5.72e-283 - - - M - - - Psort location OuterMembrane, score
NEPIEIGG_01305 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NEPIEIGG_01306 3.79e-62 - - - S - - - COG NOG23401 non supervised orthologous group
NEPIEIGG_01307 9.47e-304 lptD - - M - - - COG NOG06415 non supervised orthologous group
NEPIEIGG_01308 4.8e-106 surA 5.2.1.8 - M ko:K03771 - ko00000,ko01000,ko03110 peptidylprolyl isomerase
NEPIEIGG_01310 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NEPIEIGG_01312 8.52e-74 - - - S - - - Metallo-beta-lactamase superfamily
NEPIEIGG_01313 1.92e-45 cobS 2.7.8.26 - H ko:K02233 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NEPIEIGG_01314 4.49e-130 cobC 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01315 0.0 - - - T - - - COG0642 Signal transduction histidine kinase
NEPIEIGG_01316 0.0 - - - T - - - histidine kinase DNA gyrase B
NEPIEIGG_01317 1.38e-227 cobD 6.3.1.10 - H ko:K02227 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NEPIEIGG_01318 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
NEPIEIGG_01319 6.41e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NEPIEIGG_01320 2.06e-160 - - - F - - - NUDIX domain
NEPIEIGG_01321 0.0 - - - S ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NEPIEIGG_01322 8.43e-241 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
NEPIEIGG_01324 2.07e-104 - - - L - - - COG NOG29822 non supervised orthologous group
NEPIEIGG_01326 6.82e-38 - - - - - - - -
NEPIEIGG_01327 1.05e-107 - - - L - - - DNA-binding protein
NEPIEIGG_01328 3.31e-51 - - - S - - - Domain of unknown function (DUF4248)
NEPIEIGG_01329 6.41e-93 - - - S - - - Domain of unknown function (DUF4890)
NEPIEIGG_01330 3.67e-126 - - - S - - - COG NOG28695 non supervised orthologous group
NEPIEIGG_01331 2.21e-227 - - - I - - - Inositolphosphotransferase 1, involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), which is the most abundant sphingolipid in cells, mutation confers resistance to the antifungals syringomycin E and DmAMP1 in some growth media
NEPIEIGG_01332 7.45e-150 pgsA1 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NEPIEIGG_01333 1.51e-126 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01334 2.61e-106 pgpA 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01335 0.0 ino1 5.5.1.4 - I ko:K01858 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 ko00000,ko00001,ko01000 Inositol-3-phosphate synthase
NEPIEIGG_01336 0.0 - - - M - - - COG NOG06397 non supervised orthologous group
NEPIEIGG_01337 6.97e-51 - - - GM - - - Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NEPIEIGG_01338 1.2e-39 - - - H - - - Prokaryotic homologs of the JAB domain
NEPIEIGG_01340 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
NEPIEIGG_01341 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3
NEPIEIGG_01342 1.72e-13 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3
NEPIEIGG_01343 1.07e-154 - - - S - - - Outer membrane protein beta-barrel domain
NEPIEIGG_01344 9.72e-268 qseC - - T - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01345 4.59e-98 - - - S - - - COG NOG31508 non supervised orthologous group
NEPIEIGG_01346 4.23e-120 - - - S - - - COG NOG31242 non supervised orthologous group
NEPIEIGG_01347 5.61e-293 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 COG1760 L-serine deaminase
NEPIEIGG_01348 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NEPIEIGG_01349 1.8e-130 slyD 5.2.1.8 - G ko:K03775 - ko00000,ko01000,ko03110 Psort location Cytoplasmic, score
NEPIEIGG_01350 1.92e-284 - - - S - - - Belongs to the UPF0597 family
NEPIEIGG_01351 2.39e-188 - - - S - - - Domain of unknown function (DUF4925)
NEPIEIGG_01352 4.88e-262 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NEPIEIGG_01354 2.09e-266 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NEPIEIGG_01355 1.31e-116 - - - L - - - DNA-binding protein
NEPIEIGG_01361 5.36e-122 - - - K - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01362 1.63e-179 ric - - C ko:K07322 - ko00000 Di-iron-containing protein involved in the repair of iron-sulfur clusters
NEPIEIGG_01363 1.61e-85 - - - S - - - Protein of unknown function, DUF488
NEPIEIGG_01364 0.0 - - - L - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01365 9.33e-48 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01366 3.01e-126 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Conserved protein
NEPIEIGG_01367 1.69e-188 - - - O - - - COG COG0457 FOG TPR repeat
NEPIEIGG_01368 2.84e-77 ridA 3.5.99.10 - J ko:K09022 - ko00000,ko01000 endoribonuclease L-PSP
NEPIEIGG_01369 1.45e-54 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Folylpolyglutamate synthase
NEPIEIGG_01370 4.61e-221 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Folylpolyglutamate synthase
NEPIEIGG_01371 0.0 ybeZ_1 - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
NEPIEIGG_01373 2.14e-259 - - - E - - - COG NOG09493 non supervised orthologous group
NEPIEIGG_01374 0.0 - - - CO - - - COG NOG24773 non supervised orthologous group
NEPIEIGG_01375 0.0 - - - S - - - Oxidoreductase NAD-binding domain protein
NEPIEIGG_01376 7.67e-80 - - - K - - - Transcriptional regulator
NEPIEIGG_01379 0.0 - - - KT - - - COG NOG11230 non supervised orthologous group
NEPIEIGG_01381 6.25e-178 - - - L ko:K06400 - ko00000 Recombinase
NEPIEIGG_01382 6.54e-66 - - - S - - - Psort location Cytoplasmic, score 8.87
NEPIEIGG_01385 9.34e-317 ugd 1.1.1.22 - C ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NEPIEIGG_01387 0.0 - - - S - - - P-loop ATPase and inactivated derivatives
NEPIEIGG_01388 7.67e-56 - - - S - - - Domain of unknown function (DUF4248)
NEPIEIGG_01389 9.77e-160 - - - S - - - COG NOG26960 non supervised orthologous group
NEPIEIGG_01390 1.96e-137 - - - S - - - protein conserved in bacteria
NEPIEIGG_01391 0.0 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NEPIEIGG_01392 0.0 - - - P ko:K03305 - ko00000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01393 3.58e-206 etfB - - C ko:K03521 - ko00000 COG2086 Electron transfer flavoprotein beta subunit
NEPIEIGG_01394 4.39e-244 etfA - - C ko:K03522 - ko00000,ko04147 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01395 1.63e-158 - - - M ko:K03832 - ko00000,ko02000 MORN repeat variant
NEPIEIGG_01396 0.0 acd - - C - - - Acyl-CoA dehydrogenase, C-terminal domain
NEPIEIGG_01397 9.17e-67 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01398 1.6e-125 dnaJ2 - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 Psort location Cytoplasmic, score
NEPIEIGG_01400 2.68e-111 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NEPIEIGG_01401 2.98e-247 - - - G - - - Glycosyl hydrolase family 63 C-terminal domain
NEPIEIGG_01402 6.46e-104 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
NEPIEIGG_01403 1.31e-175 - - - S ko:K09955 - ko00000 Beta-L-arabinofuranosidase, GH127
NEPIEIGG_01404 1.46e-148 - - - F - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01405 6.56e-227 - - - M - - - Right handed beta helix region
NEPIEIGG_01406 0.0 - - - P ko:K07085 - ko00000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01410 4.59e-194 - - - K - - - Pfam:SusD
NEPIEIGG_01411 0.0 - - - P - - - TonB dependent receptor
NEPIEIGG_01412 3.51e-68 - - - T - - - cheY-homologous receiver domain
NEPIEIGG_01413 0.0 - - - P ko:K21573 - ko00000,ko02000 TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_01414 1.91e-191 - - - S ko:K21572 - ko00000,ko02000 Pfam:SusD
NEPIEIGG_01415 4.04e-98 nuoH 1.6.5.3 - C ko:K00337 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NEPIEIGG_01416 5.07e-103 nuoI 1.6.5.3 - C ko:K00338 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NEPIEIGG_01417 1.45e-108 nuoJ 1.6.5.3 - C ko:K00339 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG0839 NADH ubiquinone oxidoreductase subunit 6 (chain J)
NEPIEIGG_01418 1.01e-62 nuoK 1.6.5.3 - C ko:K00340 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NEPIEIGG_01419 0.0 nuoL 1.6.5.3 - CP ko:K00341 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit
NEPIEIGG_01420 0.0 nuoM 1.6.5.3 - C ko:K00342 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 proton-translocating NADH-quinone oxidoreductase, chain M
NEPIEIGG_01421 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine phosphoribosylpyrophosphate amidotransferase
NEPIEIGG_01422 7.16e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NEPIEIGG_01423 2.11e-274 gcvT 2.1.2.10 - H ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
NEPIEIGG_01424 6.18e-312 - - - S - - - Peptidase family M48
NEPIEIGG_01425 0.0 - - - S - - - COG NOG07965 non supervised orthologous group
NEPIEIGG_01426 1.6e-206 - - - S - - - Protein of unknown function (DUF3108)
NEPIEIGG_01427 1.17e-96 paaI - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 phenylacetic acid degradation protein
NEPIEIGG_01428 1.05e-295 - - - O - - - Glycosyl Hydrolase Family 88
NEPIEIGG_01429 1.04e-247 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NEPIEIGG_01430 4.49e-305 cap - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NEPIEIGG_01431 1.41e-303 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01433 0.0 - - - CP - - - COG3119 Arylsulfatase A
NEPIEIGG_01434 0.0 - - - - - - - -
NEPIEIGG_01435 0.0 nagA - - M - - - COG1680 Beta-lactamase class C and other penicillin binding
NEPIEIGG_01436 5.17e-219 - 3.1.3.5, 3.6.1.45 - F ko:K01081,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Ser Thr phosphatase family protein
NEPIEIGG_01437 1.74e-177 ushA 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
NEPIEIGG_01441 4.63e-88 - - - S - - - Psort location Cytoplasmic, score
NEPIEIGG_01445 1.3e-237 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01446 8.8e-264 - - - O - - - Antioxidant, AhpC TSA family
NEPIEIGG_01447 1.61e-88 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NEPIEIGG_01448 1.83e-185 - 1.5.1.38, 1.5.1.39 - C ko:K19285,ko:K19286 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Nitroreductase family
NEPIEIGG_01449 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NEPIEIGG_01450 2.08e-189 - - - Q ko:K02067 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component
NEPIEIGG_01453 6.76e-56 hupA - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
NEPIEIGG_01454 9.25e-258 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG1194 A G-specific DNA glycosylase
NEPIEIGG_01455 3.19e-105 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
NEPIEIGG_01456 1.98e-314 gldE - - S - - - Gliding motility-associated protein GldE
NEPIEIGG_01460 0.0 kdpA 3.6.3.12 - P ko:K01546 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NEPIEIGG_01461 0.0 - - - T ko:K02481 - ko00000,ko02022 acetoacetate metabolism regulatory protein AtoC
NEPIEIGG_01462 1.58e-55 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NEPIEIGG_01463 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NEPIEIGG_01464 1.26e-198 mepM_1 - - M - - - Peptidase, M23
NEPIEIGG_01465 7.42e-125 - - - S - - - COG NOG27206 non supervised orthologous group
NEPIEIGG_01467 0.0 - - - - - - - -
NEPIEIGG_01468 6.22e-34 - - - - - - - -
NEPIEIGG_01469 2.36e-141 - - - S - - - Zeta toxin
NEPIEIGG_01470 7.06e-130 - - - S - - - ATP cob(I)alamin adenosyltransferase
NEPIEIGG_01471 7.09e-296 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NEPIEIGG_01472 1.31e-147 - - - V ko:K01992 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01473 1.88e-250 - - - S - - - Domain of unknown function (DUF4466)
NEPIEIGG_01474 0.0 - 3.1.1.17 - G ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 ko00000,ko00001,ko00002,ko01000,ko04147 SMP-30/Gluconolaconase/LRE-like region
NEPIEIGG_01475 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NEPIEIGG_01476 2.12e-53 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 ATP synthase, delta epsilon subunit, beta-sandwich domain protein
NEPIEIGG_01477 1.02e-93 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01478 8.31e-253 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NEPIEIGG_01479 3.35e-33 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEPIEIGG_01480 1.59e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NEPIEIGG_01481 1.81e-128 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEPIEIGG_01482 4.59e-233 - - - P - - - Psort location OuterMembrane, score
NEPIEIGG_01483 2.45e-258 - - - P - - - Psort location OuterMembrane, score
NEPIEIGG_01484 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formyltetrahydrofolate synthetase
NEPIEIGG_01486 1.84e-155 tal 2.2.1.2 - F ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NEPIEIGG_01488 0.0 modF - - P ko:K05776 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC molybdenum transporter, ATP-binding subunit modF
NEPIEIGG_01489 1.88e-316 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
NEPIEIGG_01490 0.0 arnT - - M - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01491 3.56e-131 - - - H ko:K06950 - ko00000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01495 9.49e-89 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01496 3.7e-259 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NEPIEIGG_01497 3.55e-95 - - - S - - - YjbR
NEPIEIGG_01498 1.56e-120 - - - L - - - DNA-binding protein
NEPIEIGG_01499 3.98e-159 - - - K - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NEPIEIGG_01500 0.0 - 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 histidine kinase DNA gyrase B
NEPIEIGG_01501 3.02e-212 - - - S - - - Protein of unknown function (Porph_ging)
NEPIEIGG_01502 8.01e-227 metH_2 - - E - - - Vitamin B12 dependent methionine synthase, activation domain
NEPIEIGG_01503 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_01504 1.29e-185 dpm1 2.4.1.83 GT2 S ko:K00721 ko00510,ko01100,map00510,map01100 ko00000,ko00001,ko01000,ko01003 b-glycosyltransferase, glycosyltransferase family 2 protein
NEPIEIGG_01506 1.42e-138 dcp 3.4.15.5, 3.4.24.70 - E ko:K01284,ko:K01414 - ko00000,ko01000,ko01002 Psort location Cytoplasmic, score
NEPIEIGG_01507 1.99e-111 - - - S - - - COG NOG30732 non supervised orthologous group
NEPIEIGG_01508 1.45e-104 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 Cytidine and deoxycytidylate deaminase zinc-binding region
NEPIEIGG_01509 0.0 ctp 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
NEPIEIGG_01510 8.13e-115 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01511 9.7e-190 - 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NEPIEIGG_01512 1.27e-60 - - - S - - - COG NOG38282 non supervised orthologous group
NEPIEIGG_01513 0.0 - - - P - - - Psort location OuterMembrane, score
NEPIEIGG_01514 0.0 - - - KT - - - COG NOG11230 non supervised orthologous group
NEPIEIGG_01515 2.95e-128 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NEPIEIGG_01516 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01517 3.63e-273 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
NEPIEIGG_01519 3.53e-200 aslA - - P - - - COG COG3119 Arylsulfatase A and related enzymes
NEPIEIGG_01520 0.0 - - - M ko:K07001 - ko00000 Phospholipase, patatin family
NEPIEIGG_01521 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NEPIEIGG_01523 3.87e-305 - 3.2.1.180 GH88 M ko:K18581 - ko00000,ko01000 Glycosyl Hydrolase Family 88
NEPIEIGG_01525 9.74e-52 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01526 1.05e-120 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01527 0.0 - - - G - - - Belongs to the glycosyl hydrolase 28 family
NEPIEIGG_01528 1.92e-200 - - - - - - - -
NEPIEIGG_01529 5.35e-81 - - - K - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01530 1.58e-203 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01531 2.93e-198 cbiO - - V ko:K01990 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
NEPIEIGG_01532 4.26e-224 - - - K ko:K18954 - ko00000,ko03000 methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family) K00567
NEPIEIGG_01533 4.41e-118 - - - S - - - tetratricopeptide repeat
NEPIEIGG_01534 2.32e-117 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 Psort location CytoplasmicMembrane, score
NEPIEIGG_01535 0.0 - - - P - - - COG COG3119 Arylsulfatase A and related enzymes
NEPIEIGG_01536 6.64e-170 - - - S - - - COG NOG22668 non supervised orthologous group
NEPIEIGG_01537 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
NEPIEIGG_01538 0.0 - - - - - - - -
NEPIEIGG_01539 0.0 - - - G - - - Domain of unknown function (DUF4185)
NEPIEIGG_01540 1.26e-80 - - - S - - - Domain of unknown function (DUF4945)
NEPIEIGG_01541 7.82e-189 - - - E ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_01542 3.58e-256 - - - S - - - Tetratricopeptide repeat protein
NEPIEIGG_01543 1.4e-125 - - - S - - - COG NOG29315 non supervised orthologous group
NEPIEIGG_01544 1.84e-242 envC - - D - - - Peptidase, M23
NEPIEIGG_01545 6.93e-261 argE 3.5.1.16 - E ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related
NEPIEIGG_01546 4e-128 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
NEPIEIGG_01548 0.0 - - - C - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01549 1.88e-95 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 Glutamate--ammonia ligase, catalytic domain protein
NEPIEIGG_01550 1.46e-229 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 Glutamate--ammonia ligase, catalytic domain protein
NEPIEIGG_01551 7.81e-200 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 XFP N-terminal domain
NEPIEIGG_01552 4.19e-210 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
NEPIEIGG_01553 0.0 - - - G - - - FGGY family of carbohydrate kinases, N-terminal domain
NEPIEIGG_01555 1.34e-62 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 tRNA (Uracil-5-)-methyltransferase
NEPIEIGG_01556 7.76e-51 - - - - - - - -
NEPIEIGG_01557 7.57e-53 - - - K - - - Penicillinase repressor
NEPIEIGG_01558 1.22e-133 - - - KT - - - BlaR1 peptidase M56
NEPIEIGG_01559 8.53e-252 - - - K - - - Psort location Cytoplasmic, score
NEPIEIGG_01560 1.72e-90 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
NEPIEIGG_01561 1.27e-124 - - - M ko:K06142 - ko00000 membrane
NEPIEIGG_01562 2.46e-43 - - - S - - - COG NOG35566 non supervised orthologous group
NEPIEIGG_01563 0.0 pepD_1 - - E ko:K01270 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01564 4.86e-259 - - - S - - - Endonuclease Exonuclease phosphatase family
NEPIEIGG_01565 2.86e-95 ybdG_1 - - M ko:K16053 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01566 0.0 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NEPIEIGG_01567 7.37e-60 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NEPIEIGG_01568 8.58e-65 - - - S - - - COG NOG23407 non supervised orthologous group
NEPIEIGG_01569 1.56e-05 - - - L - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01570 2.78e-116 - - - - - - - -
NEPIEIGG_01571 3.89e-136 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01572 3.25e-80 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01573 0.0 - - - F ko:K21572 - ko00000,ko02000 COG NOG30008 non supervised orthologous group
NEPIEIGG_01574 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_01577 0.0 gltA 1.3.1.1, 1.4.1.13, 1.4.1.14 - C ko:K00266,ko:K17722 ko00240,ko00250,ko00410,ko00770,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00410,map00770,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 9.97
NEPIEIGG_01578 1.47e-226 - - - S - - - CarboxypepD_reg-like domain
NEPIEIGG_01579 3.17e-124 - - - S - - - CarboxypepD_reg-like domain
NEPIEIGG_01580 1.37e-36 - - - S - - - COG NOG17973 non supervised orthologous group
NEPIEIGG_01581 0.0 - - - P ko:K03281 - ko00000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01582 1e-240 trpB 4.2.1.20 - E ko:K06001 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NEPIEIGG_01583 1.2e-306 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NEPIEIGG_01584 7.91e-216 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01585 2.19e-26 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NEPIEIGG_01586 3.85e-98 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NEPIEIGG_01587 1.23e-225 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NEPIEIGG_01589 0.0 ppdK 2.7.9.1 - G ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the PEP-utilizing enzyme family
NEPIEIGG_01591 3.6e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Thiamine monophosphate synthase TENI
NEPIEIGG_01592 9.64e-142 sodB 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NEPIEIGG_01594 2.9e-226 - - - M - - - COG NOG23378 non supervised orthologous group
NEPIEIGG_01595 7.19e-63 - - - M - - - COG NOG23378 non supervised orthologous group
NEPIEIGG_01596 5.13e-148 - - - M - - - Protein of unknown function (DUF3575)
NEPIEIGG_01598 3.11e-100 - - - L - - - Belongs to the 'phage' integrase family
NEPIEIGG_01600 0.0 - - - S ko:K21572 - ko00000,ko02000 Pfam:SusD
NEPIEIGG_01601 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_01602 3.09e-97 - - - - - - - -
NEPIEIGG_01603 2.56e-181 exbB - - U ko:K03561 - ko00000,ko02000 MotA TolQ ExbB proton channel family
NEPIEIGG_01604 9.85e-123 exbD1 - - U - - - Biopolymer transport protein ExbD/TolR
NEPIEIGG_01605 1.05e-144 exbD2 - - U - - - Biopolymer transport protein ExbD/TolR
NEPIEIGG_01606 2.47e-184 tonB2 - - U ko:K03832 - ko00000,ko02000 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NEPIEIGG_01608 0.0 - - - E - - - Transglutaminase-like protein
NEPIEIGG_01609 1.25e-93 - - - S - - - protein conserved in bacteria
NEPIEIGG_01610 8.9e-179 - - - H - - - TonB-dependent receptor plug domain
NEPIEIGG_01611 4.91e-203 ispE 2.7.1.148 - F ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NEPIEIGG_01612 5.16e-115 - - - S - - - COG NOG29454 non supervised orthologous group
NEPIEIGG_01613 4.68e-281 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NEPIEIGG_01614 1.04e-281 - - - H - - - COG NOG06391 non supervised orthologous group
NEPIEIGG_01615 8.37e-246 - - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system permease component
NEPIEIGG_01616 2.81e-221 - - - V ko:K02004 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
NEPIEIGG_01617 1.08e-102 - - - S - - - COG NOG30399 non supervised orthologous group
NEPIEIGG_01618 1.2e-226 - - - S - - - protein conserved in bacteria
NEPIEIGG_01619 0.0 bglX 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 glycosyl hydrolase, family 3
NEPIEIGG_01621 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Beta galactosidase small chain
NEPIEIGG_01622 1.75e-134 - 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Beta-galactosidase trimerisation domain
NEPIEIGG_01623 0.0 - 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Beta-galactosidase trimerisation domain
NEPIEIGG_01624 1.27e-292 aspC 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I II
NEPIEIGG_01625 1.22e-288 lolE_1 - - M ko:K09808 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4591 ABC-type transport system, involved in lipoprotein release, permease component
NEPIEIGG_01626 1.35e-282 - - - M - - - Glycosyltransferase, group 2 family protein
NEPIEIGG_01627 3.96e-95 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NEPIEIGG_01628 0.0 - - - NT - - - type I restriction enzyme
NEPIEIGG_01629 0.0 pop - - EU - - - Peptidase, S9A B C family, catalytic domain protein
NEPIEIGG_01630 3.96e-122 - - - V - - - MATE efflux family protein
NEPIEIGG_01631 2.87e-54 - - - S - - - 23S rRNA-intervening sequence protein
NEPIEIGG_01632 3.23e-247 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Kinase, PfkB family
NEPIEIGG_01633 3.03e-257 - - - K ko:K02529 - ko00000,ko03000 Psort location Cytoplasmic, score
NEPIEIGG_01635 7.03e-39 - 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
NEPIEIGG_01636 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
NEPIEIGG_01638 1.9e-314 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEPIEIGG_01639 3.43e-123 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NEPIEIGG_01640 1.98e-197 nlpD_1 - - M - - - Peptidase, M23 family
NEPIEIGG_01641 1.04e-270 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NEPIEIGG_01642 1.04e-71 tilS 6.3.4.19 - D ko:K04075 - ko00000,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NEPIEIGG_01643 1.33e-190 - - - C - - - 4Fe-4S binding domain protein
NEPIEIGG_01644 0.0 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NEPIEIGG_01645 2.91e-127 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01646 8.69e-149 - - - E - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01647 0.0 nagZ3 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
NEPIEIGG_01648 2.37e-120 - - - S ko:K07095 - ko00000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01652 2.44e-113 queA 2.4.99.17 - H ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NEPIEIGG_01653 5.44e-88 queA 2.4.99.17 - H ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NEPIEIGG_01654 1.39e-166 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NEPIEIGG_01655 3.79e-176 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NEPIEIGG_01656 6.04e-49 fjo13 - - S - - - COG NOG19122 non supervised orthologous group
NEPIEIGG_01657 8.27e-193 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily
NEPIEIGG_01658 6.12e-75 - - - H - - - Methyltransferase domain protein
NEPIEIGG_01660 0.0 celA 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 5 (cellulase A) family
NEPIEIGG_01661 5.13e-150 rhaA 5.3.1.14 - G ko:K01813 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01662 6.45e-240 rhaT - - EG ko:K02856 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01663 2.72e-196 rhaD 4.1.2.19 - G ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NEPIEIGG_01664 1.04e-270 fucO 1.1.1.77 - C ko:K00048 ko00630,ko00640,ko01120,map00630,map00640,map01120 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_01665 2.94e-141 - - - - - - - -
NEPIEIGG_01666 3.71e-101 - - - - - - - -
NEPIEIGG_01667 3.91e-244 - - - - - - - -
NEPIEIGG_01668 2.11e-84 - - - - - - - -
NEPIEIGG_01671 2.14e-214 - - - M ko:K01993 - ko00000 Auxiliary transport protein, membrane fusion protein (MFP) family protein
NEPIEIGG_01672 1.87e-310 - - - MU - - - Psort location OuterMembrane, score
NEPIEIGG_01673 7.02e-190 - - - S - - - COG NOG11650 non supervised orthologous group
NEPIEIGG_01674 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NEPIEIGG_01675 1.2e-283 thiH 4.1.99.19 - C ko:K03150 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiazole biosynthesis protein ThiH
NEPIEIGG_01676 4.49e-167 moeZ 2.7.7.80, 2.8.1.11 - H ko:K21029,ko:K21147 ko04122,map04122 ko00000,ko00001,ko01000 involved in molybdopterin and thiamine biosynthesis family 2
NEPIEIGG_01677 1.47e-143 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Thiamine monophosphate synthase TENI
NEPIEIGG_01678 1.27e-251 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01679 1.36e-191 mazG 3.6.1.66 - S ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01680 2.58e-96 - - - S - - - COG NOG28735 non supervised orthologous group
NEPIEIGG_01681 2.03e-80 - - - S - - - COG NOG23405 non supervised orthologous group
NEPIEIGG_01682 1.49e-126 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NEPIEIGG_01683 6.06e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NEPIEIGG_01684 4.18e-52 atsB - - C ko:K06871 - ko00000 COG0641 Arylsulfatase regulator (Fe-S oxidoreductase)
NEPIEIGG_01685 1.47e-254 atsB - - C ko:K06871 - ko00000 COG0641 Arylsulfatase regulator (Fe-S oxidoreductase)
NEPIEIGG_01686 4.98e-170 - - - CO - - - Domain of unknown function (DUF4369)
NEPIEIGG_01687 1.24e-179 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NEPIEIGG_01688 2.85e-189 - - - S ko:K07098 - ko00000 Ser Thr phosphatase family protein
NEPIEIGG_01689 2e-52 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NEPIEIGG_01693 2.82e-127 kdsC 3.1.3.45 - S ko:K03270 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family
NEPIEIGG_01694 3.87e-176 - - - S - - - NADP oxidoreductase coenzyme F420-dependent
NEPIEIGG_01695 9.32e-70 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01696 3.4e-120 - - - C - - - Nitroreductase family
NEPIEIGG_01697 5.13e-240 - - - V - - - COG NOG22551 non supervised orthologous group
NEPIEIGG_01698 2.42e-232 treZ_2 - - M - - - branching enzyme
NEPIEIGG_01699 1.33e-117 cobW - - S - - - CobW P47K family protein
NEPIEIGG_01700 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
NEPIEIGG_01701 8.58e-139 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NEPIEIGG_01702 1.96e-49 - - - - - - - -
NEPIEIGG_01703 3.38e-108 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NEPIEIGG_01704 4.86e-45 - - - S - - - COG NOG17489 non supervised orthologous group
NEPIEIGG_01705 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1271 Cytochrome bd-type quinol oxidase, subunit 1
NEPIEIGG_01706 7.99e-186 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase subunit 2
NEPIEIGG_01707 5.22e-163 mtgA 2.4.1.129 GT51 M ko:K03814 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NEPIEIGG_01708 6.72e-50 - - - M - - - COG2885 Outer membrane protein and related peptidoglycan-associated
NEPIEIGG_01709 2.74e-284 - - - L - - - Belongs to the 'phage' integrase family
NEPIEIGG_01711 4.6e-250 - - - L - - - restriction
NEPIEIGG_01715 8.54e-223 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein
NEPIEIGG_01716 9.35e-226 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NEPIEIGG_01717 5.67e-177 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NEPIEIGG_01718 1.75e-134 - - - - - - - -
NEPIEIGG_01719 2.82e-177 aroE 1.1.1.25 - C ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 COG0169 Shikimate 5-dehydrogenase
NEPIEIGG_01720 1.13e-18 - - - M - - - Psort location CytoplasmicMembrane, score 9.46
NEPIEIGG_01721 2.59e-160 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
NEPIEIGG_01722 2.03e-67 yitW - - S - - - FeS assembly SUF system protein
NEPIEIGG_01723 2.15e-190 lpxH 3.6.1.54 - S ko:K03269 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Psort location Cytoplasmic, score
NEPIEIGG_01724 0.0 - - - G - - - YdjC-like protein
NEPIEIGG_01725 3.52e-48 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NEPIEIGG_01726 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEPIEIGG_01727 8.59e-144 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01728 1.51e-234 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEPIEIGG_01729 8.56e-72 - - - - - - - -
NEPIEIGG_01730 1.04e-126 - - - - - - - -
NEPIEIGG_01731 0.0 - - - - - - - -
NEPIEIGG_01733 3.18e-118 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01734 3.6e-33 radC - - L ko:K03630 - ko00000 COG2003 DNA repair
NEPIEIGG_01736 0.0 dinF - - V ko:K03327 - ko00000,ko02000 MATE efflux family protein
NEPIEIGG_01737 8.89e-153 - - - S - - - COG NOG28155 non supervised orthologous group
NEPIEIGG_01738 7.92e-125 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_01739 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 glycosyl hydrolase, family 3
NEPIEIGG_01740 0.0 - - - G - - - Glycosyl hydrolases family 28
NEPIEIGG_01741 7.22e-79 - - - L - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01742 3.25e-225 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01743 4.9e-192 - - - S - - - COG4422 Bacteriophage protein gp37
NEPIEIGG_01744 1.1e-143 - - - S - - - COG NOG14459 non supervised orthologous group
NEPIEIGG_01745 3.16e-233 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01746 3.42e-115 - - - K - - - Transcription termination antitermination factor NusG
NEPIEIGG_01747 2.88e-24 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01748 8.64e-41 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01750 6.11e-269 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01751 4.13e-107 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NEPIEIGG_01752 8.73e-96 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEPIEIGG_01753 1.4e-81 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEPIEIGG_01754 2.49e-114 - 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEPIEIGG_01755 1.52e-201 - - - KT - - - MerR, DNA binding
NEPIEIGG_01756 2.65e-215 - - - S ko:K07017 - ko00000 Putative esterase
NEPIEIGG_01758 2.11e-98 - - - S - - - COG NOG14442 non supervised orthologous group
NEPIEIGG_01759 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEPIEIGG_01760 2.89e-110 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NEPIEIGG_01761 1.88e-222 lytG - - MNU - - - COG1705 Muramidase (flagellum-specific)
NEPIEIGG_01762 4.31e-278 - - - M ko:K02005 - ko00000 Efflux transporter, RND family, MFP subunit
NEPIEIGG_01763 5.59e-96 - - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system permease component
NEPIEIGG_01764 0.0 - - - N - - - COG NOG14601 non supervised orthologous group
NEPIEIGG_01765 6.24e-78 - - - - - - - -
NEPIEIGG_01766 2.59e-276 ynfM - - EGP ko:K08224 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01767 9.84e-305 nhaC - - C ko:K03315 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01768 1.08e-86 glpE - - P - - - Rhodanese-like protein
NEPIEIGG_01769 5.25e-157 - - - S - - - COG NOG31798 non supervised orthologous group
NEPIEIGG_01770 1.45e-279 - - - I - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01771 1.35e-236 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NEPIEIGG_01772 6.01e-174 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NEPIEIGG_01773 5.55e-97 arnC - - M - - - involved in cell wall biogenesis
NEPIEIGG_01774 6.05e-108 - - - S - - - COG NOG30522 non supervised orthologous group
NEPIEIGG_01775 5.95e-193 - - - S - - - COG NOG28307 non supervised orthologous group
NEPIEIGG_01776 1.52e-123 mntP - - P - - - Probably functions as a manganese efflux pump
NEPIEIGG_01777 1.04e-246 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEPIEIGG_01778 5.57e-83 - - - S ko:K09922 - ko00000 Psort location CytoplasmicMembrane, score
NEPIEIGG_01779 9.15e-69 ttcA - - H ko:K14058 - ko00000,ko03016 Belongs to the TtcA family
NEPIEIGG_01780 8.21e-256 - - - M ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_01781 3.2e-261 - - - G - - - Histidine acid phosphatase
NEPIEIGG_01782 3.01e-107 ispF 4.6.1.12 - H ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NEPIEIGG_01783 3.54e-230 - - - S ko:K01163 - ko00000 Conserved protein
NEPIEIGG_01784 3.09e-149 lrgB - - M - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01785 2.1e-71 lrgA - - S ko:K06518 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
NEPIEIGG_01787 3.55e-234 pta 2.3.1.8 - C ko:K00625,ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_01788 2.8e-229 - - - L - - - Belongs to the 'phage' integrase family
NEPIEIGG_01789 1.19e-184 - - - - - - - -
NEPIEIGG_01790 1.22e-257 - - - S ko:K07037 - ko00000 7TM receptor with intracellular HD hydrolase
NEPIEIGG_01791 0.000703 - - - S - - - COG NOG32529 non supervised orthologous group
NEPIEIGG_01792 0.0 - - - S - - - Phosphoadenosine phosphosulfate reductase family
NEPIEIGG_01793 2.93e-125 ibrB - - K - - - Psort location Cytoplasmic, score
NEPIEIGG_01794 4.49e-232 - 4.1.1.35 - GM ko:K08678 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase dehydratase family
NEPIEIGG_01796 3.11e-292 rsmF - - J - - - NOL1 NOP2 sun family
NEPIEIGG_01797 5.46e-299 - - - O ko:K13963 ko05146,map05146 ko00000,ko00001 SERine Proteinase INhibitors
NEPIEIGG_01798 4.28e-248 - - - MU - - - outer membrane efflux protein
NEPIEIGG_01799 0.0 yaeT - - M ko:K07277 - ko00000,ko02000,ko03029 Outer membrane protein assembly complex, YaeT protein
NEPIEIGG_01800 2.05e-104 ompH - - M ko:K06142 - ko00000 membrane
NEPIEIGG_01801 4.15e-75 - - - M ko:K06142 - ko00000 Membrane
NEPIEIGG_01802 3.32e-202 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NEPIEIGG_01803 3.66e-154 pgl 3.1.1.31 - G ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase
NEPIEIGG_01804 1.13e-91 yhiM - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01805 6.45e-99 yhiM - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01806 7.24e-160 pdxH 1.4.3.5 - H ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
NEPIEIGG_01807 1.68e-156 - - - U ko:K03832 - ko00000,ko02000 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NEPIEIGG_01809 1.07e-256 - 5.1.3.11 - M ko:K16213 - ko00000,ko01000 Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)
NEPIEIGG_01810 1.04e-173 - - - K - - - Pfam:SusD
NEPIEIGG_01811 1.13e-117 - - - S - - - UPF0365 protein
NEPIEIGG_01812 1.94e-212 udp 2.4.2.3 - F ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_01813 1.57e-95 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NEPIEIGG_01814 1.44e-211 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NEPIEIGG_01815 8.55e-17 - - - - - - - -
NEPIEIGG_01816 0.0 bglB 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
NEPIEIGG_01818 5.46e-183 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NEPIEIGG_01819 1.58e-250 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NEPIEIGG_01821 0.0 - - - U - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NEPIEIGG_01822 6.16e-81 - - - K - - - Transcriptional regulator, BlaI MecI CopY family
NEPIEIGG_01823 4.07e-96 - - - D ko:K07322 - ko00000 Hemerythrin HHE cation binding domain protein
NEPIEIGG_01824 2.24e-140 - - - K - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NEPIEIGG_01825 4.42e-172 cbiD 2.1.1.195 - H ko:K02188 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
NEPIEIGG_01826 6.19e-85 - - - M - - - COG NOG19089 non supervised orthologous group
NEPIEIGG_01827 2.37e-54 - - - M - - - COG NOG19089 non supervised orthologous group
NEPIEIGG_01828 4e-258 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NEPIEIGG_01829 1.15e-296 norM - - V - - - MATE efflux family protein
NEPIEIGG_01830 5.28e-133 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01831 3.7e-128 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
NEPIEIGG_01832 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NEPIEIGG_01833 2.14e-243 - - - H - - - Psort location OuterMembrane, score
NEPIEIGG_01834 0.0 nuoC 1.6.5.3 - C ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NEPIEIGG_01835 2.37e-141 nuoB 1.6.5.3 - C ko:K00331 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NEPIEIGG_01836 2.07e-73 nuoA 1.6.5.3 - C ko:K00330 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NEPIEIGG_01837 4.56e-87 - - - - - - - -
NEPIEIGG_01838 3.89e-39 trkH - - P ko:K03498 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01839 1.52e-144 - - - L - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01840 2.79e-69 - - - S - - - Nucleotidyltransferase domain
NEPIEIGG_01841 5.4e-79 - - - H - - - Nucleotidyltransferase substrate-binding family protein
NEPIEIGG_01842 1.64e-142 - - - - - - - -
NEPIEIGG_01843 5.07e-108 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Involved in allosteric regulation of aspartate carbamoyltransferase
NEPIEIGG_01844 9.76e-229 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NEPIEIGG_01848 1.66e-87 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NEPIEIGG_01849 9.92e-110 mreD - - S - - - rod shape-determining protein MreD
NEPIEIGG_01850 0.0 mrdA 3.4.16.4 - M ko:K05515 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein 2
NEPIEIGG_01851 1.73e-221 - - - S ko:K03453 - ko00000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01853 2.18e-232 - - - L - - - Belongs to the 'phage' integrase family
NEPIEIGG_01854 0.0 - - - S - - - Tetratricopeptide repeat protein
NEPIEIGG_01855 1.13e-29 - - - H - - - Psort location OuterMembrane, score
NEPIEIGG_01856 0.0 - - - H - - - Psort location OuterMembrane, score
NEPIEIGG_01857 1.08e-116 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NEPIEIGG_01858 1.73e-93 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NEPIEIGG_01859 0.0 - - - S - - - Psort location OuterMembrane, score 9.49
NEPIEIGG_01860 3.88e-108 - - - S ko:K08999 - ko00000 Conserved protein
NEPIEIGG_01861 5.9e-168 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NEPIEIGG_01862 0.0 - - - S - - - COG NOG26882 non supervised orthologous group
NEPIEIGG_01863 2.15e-152 - - - V ko:K02003 - ko00000,ko00002,ko02000 COG1136 ABC-type antimicrobial peptide transport system ATPase component
NEPIEIGG_01865 3.25e-84 - - - M - - - Glycosyl transferase family 2
NEPIEIGG_01866 6.43e-225 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NEPIEIGG_01868 0.0 - - - C ko:K09181 - ko00000 CoA binding domain protein
NEPIEIGG_01869 4.69e-273 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI
NEPIEIGG_01870 9.99e-59 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI
NEPIEIGG_01871 5.6e-262 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog
NEPIEIGG_01872 2.21e-148 - - - I - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01873 1.75e-86 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
NEPIEIGG_01874 4.33e-105 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NEPIEIGG_01875 1.57e-130 - - - L - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01876 3.53e-254 ilvC 1.1.1.86 - E ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ketol-acid reductoisomerase
NEPIEIGG_01877 9.44e-183 - 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
NEPIEIGG_01878 1.36e-126 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 COG0440 Acetolactate synthase, small (regulatory) subunit
NEPIEIGG_01879 2.38e-159 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetolactate synthase, large subunit
NEPIEIGG_01881 1.51e-211 emrA_1 - - V ko:K03543 - ko00000,ko00002,ko02000 Auxiliary transport protein, membrane fusion protein (MFP) family protein
NEPIEIGG_01882 4.09e-294 - - - MU - - - Outer membrane efflux protein
NEPIEIGG_01884 6.12e-76 - - - S - - - Cupin domain
NEPIEIGG_01887 1.03e-09 - - - - - - - -
NEPIEIGG_01888 2.65e-81 - - - K - - - Bacterial regulatory proteins, gntR family
NEPIEIGG_01889 7.14e-185 - - - - - - - -
NEPIEIGG_01890 5.97e-58 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NEPIEIGG_01891 4.29e-140 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01892 7.54e-178 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family
NEPIEIGG_01893 5.61e-113 - - - S - - - Family of unknown function (DUF3836)
NEPIEIGG_01894 1.33e-225 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin biosynthesis protein
NEPIEIGG_01895 1.94e-72 yihX 3.1.3.10 - S ko:K07025,ko:K20866 ko00010,ko01120,map00010,map01120 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01896 3.24e-303 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NEPIEIGG_01897 3.1e-138 folE 3.5.4.16 - F ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase I
NEPIEIGG_01898 1.34e-99 - - - S - - - Sporulation and cell division repeat protein
NEPIEIGG_01899 1.49e-175 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NEPIEIGG_01900 1.52e-69 doxX - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01901 1.17e-210 - - - G - - - Glycosyl hydrolase family 92
NEPIEIGG_01902 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NEPIEIGG_01903 1.32e-82 amyA 3.2.1.1 GH57 G ko:K07405 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 57 family
NEPIEIGG_01904 0.0 - - - S - - - Domain of unknown function (DUF4270)
NEPIEIGG_01905 5.3e-201 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Starch synthase, catalytic domain
NEPIEIGG_01907 0.0 - - - P - - - TonB-dependent receptor
NEPIEIGG_01908 1.06e-83 yccF - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01909 9.08e-165 - - - P - - - TonB-dependent receptor
NEPIEIGG_01910 0.0 - - - M - - - CarboxypepD_reg-like domain
NEPIEIGG_01911 2.85e-160 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
NEPIEIGG_01912 9.63e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Psort location Cytoplasmic, score 9.97
NEPIEIGG_01913 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_01914 1.42e-135 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEPIEIGG_01915 6.13e-174 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01916 1.6e-160 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01917 6.94e-134 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01918 8.86e-127 nrdG 1.97.1.4 - C ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEPIEIGG_01919 1.57e-49 nrdD 1.1.98.6 - FK ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01920 7.21e-126 - - - I - - - PLD-like domain
NEPIEIGG_01921 0.0 - - - S - - - Domain of unknown function (DUF1998)
NEPIEIGG_01922 3.08e-158 - - - L - - - Helicase conserved C-terminal domain
NEPIEIGG_01923 9.77e-120 - - - L - - - Helicase conserved C-terminal domain
NEPIEIGG_01924 0.0 - - - T - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_01925 4.05e-51 chrA - - P ko:K07240 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
NEPIEIGG_01927 3.92e-129 - - - P ko:K07240 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01928 9.11e-296 yngK - - S - - - lipoprotein YddW precursor
NEPIEIGG_01929 0.0 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01930 7.85e-69 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NEPIEIGG_01931 3.94e-73 cyaA 4.6.1.1 - S ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01932 1.14e-09 - - - - - - - -
NEPIEIGG_01933 1.71e-264 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NEPIEIGG_01934 8.77e-188 - - - T - - - COG NOG17272 non supervised orthologous group
NEPIEIGG_01935 5.17e-158 - - - Q - - - depolymerase
NEPIEIGG_01936 2.52e-204 - - - S - - - Putative beta-lactamase-inhibitor-like, PepSY-like
NEPIEIGG_01937 2.19e-105 - - - S - - - COG NOG19145 non supervised orthologous group
NEPIEIGG_01938 1.75e-220 - - - - - - - -
NEPIEIGG_01939 2.05e-178 - - - K - - - LytTr DNA-binding domain protein
NEPIEIGG_01940 9.59e-69 cbiE 2.1.1.132 - H ko:K00595 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE
NEPIEIGG_01941 0.0 cobM 2.1.1.133, 2.1.1.271 - H ko:K05936 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 COG2875 Precorrin-4 methylase
NEPIEIGG_01944 3.65e-76 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHH family
NEPIEIGG_01945 3.73e-143 - - - S - - - COG NOG30041 non supervised orthologous group
NEPIEIGG_01946 1.48e-42 glmM 5.4.2.8 - G ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01947 9.99e-277 glmM 5.4.2.8 - G ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_01949 9.47e-317 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NEPIEIGG_01951 1.07e-286 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NEPIEIGG_01952 3.38e-109 ftnA 1.16.3.2 - P ko:K02217 - ko00000,ko01000 Iron-storage protein
NEPIEIGG_01953 6.58e-52 kbl 2.3.1.29 - H ko:K00639 ko00260,map00260 ko00000,ko00001,ko01000,ko01007 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA
NEPIEIGG_01954 0.0 - - - - - - - -
NEPIEIGG_01955 2.64e-223 - 3.2.1.37, 3.2.1.55 GH43,GH51 G ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
NEPIEIGG_01956 3.79e-250 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NEPIEIGG_01957 8.74e-193 deoD 2.4.2.1 - F ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NEPIEIGG_01958 7.16e-280 lpxK 2.7.1.130 - F ko:K00912 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
NEPIEIGG_01959 2.12e-144 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA, 67K type
NEPIEIGG_01960 2.29e-125 - - - I - - - Acyl-transferase
NEPIEIGG_01961 2.94e-235 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01962 9.4e-317 dgt 3.1.5.1 - F ko:K01129 ko00230,map00230 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_01963 1.04e-98 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NEPIEIGG_01964 8.42e-281 - - - EGP - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01965 1.28e-90 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NEPIEIGG_01966 8.64e-89 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NEPIEIGG_01967 1.96e-177 ydfG - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
NEPIEIGG_01968 0.0 potA 3.6.3.29, 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K02017,ko:K10112,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NEPIEIGG_01969 6.8e-122 - - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01970 3.56e-41 - - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01971 3.02e-116 - - - G - - - Repeats in polycystic kidney disease 1 (PKD1) and other proteins
NEPIEIGG_01973 4.22e-183 - - - G - - - Psort location Extracellular, score
NEPIEIGG_01974 4.35e-93 - - - O - - - Dual-action HEIGH metallo-peptidase
NEPIEIGG_01976 1.22e-248 - 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase dehydratase family
NEPIEIGG_01977 4.16e-233 - - - I - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01979 5.49e-236 dus - - H - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEPIEIGG_01980 3.06e-279 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
NEPIEIGG_01982 2.39e-116 - - - - - - - -
NEPIEIGG_01983 3.55e-36 rfaE 2.7.1.167, 2.7.7.70 - H ko:K03272 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NEPIEIGG_01984 1.26e-244 - - GT9 M ko:K02843 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyltransferase family 9
NEPIEIGG_01985 3.48e-214 - 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 COG COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase
NEPIEIGG_01986 1.63e-127 - - - M - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01987 2.05e-231 - - - GM - - - NAD dependent epimerase dehydratase family
NEPIEIGG_01988 1.07e-212 wcgX 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_01992 5.97e-238 uvrD2 - - L - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_01993 1.17e-217 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NEPIEIGG_01994 2.97e-142 - - - S - - - COG NOG28927 non supervised orthologous group
NEPIEIGG_01995 1.35e-139 - - - - - - - -
NEPIEIGG_01996 5.32e-40 hutI 3.5.2.7 - F ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
NEPIEIGG_01997 7.11e-135 fchA - - E - - - COG3404 Methenyl tetrahydrofolate cyclohydrolase
NEPIEIGG_01998 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
NEPIEIGG_01999 4.32e-155 - - - K - - - transcriptional regulator, TetR family
NEPIEIGG_02000 1e-248 - - - T - - - Histidine kinase
NEPIEIGG_02001 2.6e-167 - - - K - - - LytTr DNA-binding domain
NEPIEIGG_02002 2.87e-308 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Psort location Cytoplasmic, score
NEPIEIGG_02003 0.0 eptA - - S - - - lipid A phosphoethanolamine transferase, associated with polymyxin resistance
NEPIEIGG_02004 3.3e-94 - - - S - - - COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
NEPIEIGG_02005 0.0 - - - S ko:K07079 - ko00000 4Fe-4S dicluster domain
NEPIEIGG_02006 7.45e-101 - - - G - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02007 4.82e-281 - - - S - - - COG NOG33609 non supervised orthologous group
NEPIEIGG_02008 1.06e-301 - - - - - - - -
NEPIEIGG_02009 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NEPIEIGG_02010 1.73e-257 - - - S - - - COG NOG28036 non supervised orthologous group
NEPIEIGG_02011 1.46e-195 - - - K - - - Transcriptional regulator
NEPIEIGG_02012 3.55e-230 - - - C - - - 4Fe-4S dicluster domain
NEPIEIGG_02013 0.0 susB 3.2.1.20, 3.2.1.3 GH31,GH97 G ko:K01187,ko:K21574 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG NOG06228 non supervised orthologous group
NEPIEIGG_02014 3.05e-96 - - - E - - - COG NOG04781 non supervised orthologous group
NEPIEIGG_02015 0.0 ahpF - - C ko:K03387 - ko00000,ko01000 alkyl hydroperoxide reductase subunit F
NEPIEIGG_02016 2.47e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Psort location Cytoplasmic, score
NEPIEIGG_02017 2.36e-121 oxyR - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 Psort location Cytoplasmic, score 9.97
NEPIEIGG_02019 1.92e-112 cobQ 6.3.5.10 - H ko:K02232 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
NEPIEIGG_02020 4.5e-237 cobQ 6.3.5.10 - H ko:K02232 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
NEPIEIGG_02021 3.46e-160 - - - MU - - - Psort location OuterMembrane, score
NEPIEIGG_02023 2.36e-63 - 3.2.1.89 - G ko:K01224 - ko00000,ko01000 Glycosyl hydrolase family 53
NEPIEIGG_02024 0.0 - 3.2.1.135 GH13 G ko:K21575 - ko00000,ko01000 Alpha-amylase domain
NEPIEIGG_02026 3.81e-272 aguA 3.5.3.12 - E ko:K10536 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_02027 1.29e-124 - - - S - - - protein containing a ferredoxin domain
NEPIEIGG_02028 1.84e-145 - 3.6.3.21 - V ko:K02028,ko:K02068 - ko00000,ko00002,ko01000,ko02000 ABC transporter
NEPIEIGG_02030 4.02e-261 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NEPIEIGG_02031 1.5e-53 - - - S - - - Virulence protein RhuM family
NEPIEIGG_02032 1.46e-198 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEPIEIGG_02034 1.18e-66 - - - T - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02035 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEPIEIGG_02036 0.0 abf2 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase domain protein
NEPIEIGG_02037 0.0 araB - - G - - - Carbohydrate kinase, FGGY family protein
NEPIEIGG_02039 2.19e-230 - - - PT - - - Sigma factor regulatory protein, FecR PupR family
NEPIEIGG_02040 1.87e-133 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor
NEPIEIGG_02043 2.59e-79 hppA 3.6.1.1 - C ko:K15987 ko00190,map00190 ko00000,ko00001,ko01000 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
NEPIEIGG_02045 0.0 - - - F ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_02046 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_02047 0.0 - - - S - - - Peptidase M16 inactive domain
NEPIEIGG_02048 6.65e-149 yadS - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02050 7.7e-157 - - - S - - - Capsule assembly protein Wzi
NEPIEIGG_02051 1.33e-128 rfbC 5.1.3.13 - G ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NEPIEIGG_02052 2.66e-315 ugd 1.1.1.22 - C ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NEPIEIGG_02053 9.87e-189 - - - S - - - COG NOG26711 non supervised orthologous group
NEPIEIGG_02054 0.0 - - - P - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02055 1.42e-57 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
NEPIEIGG_02056 1.42e-62 - - - - - - - -
NEPIEIGG_02057 1.99e-80 - - - K - - - Transcriptional regulator, HxlR family
NEPIEIGG_02058 0.0 - 5.1.3.11 - M ko:K16213 - ko00000,ko01000 Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)
NEPIEIGG_02060 0.0 - - - L - - - COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
NEPIEIGG_02061 1.53e-147 yciO - - J - - - Belongs to the SUA5 family
NEPIEIGG_02062 2.17e-258 pfp 2.7.1.11, 2.7.1.90 - H ko:K00895,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
NEPIEIGG_02063 3.27e-188 acm - - M ko:K07273 - ko00000 phage tail component domain protein
NEPIEIGG_02064 9.37e-294 - - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system permease component
NEPIEIGG_02065 2.3e-216 - - - M - - - Dipeptidase
NEPIEIGG_02066 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II
NEPIEIGG_02067 9.71e-105 nudC 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 COG COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding
NEPIEIGG_02068 0.0 - - - P - - - TonB dependent receptor
NEPIEIGG_02069 4.88e-195 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEPIEIGG_02070 5.94e-296 fprA 1.6.3.4 - C ko:K22405 - ko00000,ko01000 anaerobic nitric oxide reductase flavorubredoxin
NEPIEIGG_02071 1.02e-141 - - - S ko:K07139 - ko00000 radical SAM protein, TIGR01212 family
NEPIEIGG_02072 0.0 ravA_1 - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
NEPIEIGG_02073 0.0 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02074 1.41e-43 - - - H ko:K02014 - ko00000,ko02000 COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
NEPIEIGG_02075 1.58e-207 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NEPIEIGG_02076 2.18e-246 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEPIEIGG_02077 4.97e-40 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NEPIEIGG_02078 8.58e-139 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02081 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NEPIEIGG_02082 3.5e-255 agcS - - E ko:K03310 - ko00000 amino acid carrier protein
NEPIEIGG_02083 8.45e-147 - - - S - - - COG NOG25304 non supervised orthologous group
NEPIEIGG_02085 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_02086 0.0 - 3.2.1.25 - G ko:K01192 ko00511,ko04142,map00511,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 2, sugar binding domain protein
NEPIEIGG_02087 1.24e-36 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02088 2.31e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NEPIEIGG_02089 2.52e-302 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NEPIEIGG_02090 2.5e-58 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_02091 7.76e-280 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_02092 0.0 prpC 2.3.3.1, 2.3.3.5 - C ko:K01647,ko:K01659 ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_02094 1.55e-220 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 COG3250 Beta-galactosidase beta-glucuronidase
NEPIEIGG_02095 3.08e-57 - - - S - - - COG NOG18433 non supervised orthologous group
NEPIEIGG_02096 7.83e-112 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_02098 0.0 - - - H - - - Psort location OuterMembrane, score
NEPIEIGG_02099 2.74e-138 - 3.1.6.6 - P ko:K01133 - ko00000,ko01000 COG COG3119 Arylsulfatase A and related enzymes
NEPIEIGG_02100 2.53e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NEPIEIGG_02101 1.58e-207 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NEPIEIGG_02102 8.19e-82 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
NEPIEIGG_02104 0.0 - - - S - - - Protein of unknown function (DUF3078)
NEPIEIGG_02105 1.48e-116 yajL 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 Psort location Cytoplasmic, score
NEPIEIGG_02106 1.84e-159 - - - M - - - TonB family domain protein
NEPIEIGG_02107 9.89e-86 - - - U ko:K03559 - ko00000,ko02000 Transport energizing protein, ExbD TolR family
NEPIEIGG_02108 8.63e-164 exbB - - U ko:K03561 - ko00000,ko02000 MotA TolQ ExbB proton channel family
NEPIEIGG_02109 6.73e-79 pdxJ 2.6.99.2 - H ko:K03474 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NEPIEIGG_02110 0.0 - 3.2.1.20 GH31 M ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG NOG06228 non supervised orthologous group
NEPIEIGG_02111 7.82e-154 - - - S - - - COG NOG26965 non supervised orthologous group
NEPIEIGG_02112 2.63e-155 - - - M - - - COG NOG27406 non supervised orthologous group
NEPIEIGG_02113 1e-63 nagA - - G - - - b-glycosidase, glycoside hydrolase family 3 protein
NEPIEIGG_02114 9.09e-113 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NEPIEIGG_02115 3e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 50S ribosomal protein L30
NEPIEIGG_02116 1.72e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
NEPIEIGG_02117 2.12e-308 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NEPIEIGG_02118 5.08e-195 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Psort location Cytoplasmic, score
NEPIEIGG_02119 2.35e-08 - - - - - - - -
NEPIEIGG_02120 6.23e-111 - 3.5.1.28 - V ko:K01447 - ko00000,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_02121 3.55e-127 - - - K - - - Transcription termination antitermination factor NusG
NEPIEIGG_02122 0.0 ptk_3 - - DM - - - Chain length determinant protein
NEPIEIGG_02123 8.31e-12 - - - - - - - -
NEPIEIGG_02124 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
NEPIEIGG_02125 2.3e-135 tabA_1 - - G - - - COG COG2731 Beta-galactosidase, beta subunit
NEPIEIGG_02126 5.4e-135 - - - S - - - Calcineurin-like phosphoesterase
NEPIEIGG_02127 9.39e-124 - - - K - - - COG2207 AraC-type DNA-binding domain-containing
NEPIEIGG_02128 0.0 copA 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02129 6.56e-64 - - - P ko:K08364 - ko00000,ko02000 Heavy metal-associated domain protein
NEPIEIGG_02130 7.09e-112 - - - P - - - COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
NEPIEIGG_02131 3.54e-105 - - - K - - - transcriptional regulator (AraC
NEPIEIGG_02132 0.0 - 3.4.14.4 - S ko:K01277 - ko00000,ko01000,ko01002 Peptidase family M49
NEPIEIGG_02133 1.94e-119 - - - Q - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02134 2.76e-272 - - - N - - - Psort location OuterMembrane, score
NEPIEIGG_02135 1.53e-156 - - - S - - - Protein of unknown function (DUF2490)
NEPIEIGG_02136 1.2e-200 - - - G - - - Glycosyl hydrolase family 2, sugar binding domain protein
NEPIEIGG_02137 0.0 rhaB 2.7.1.5, 2.7.1.51 - G ko:K00848,ko:K00879 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NEPIEIGG_02139 9.87e-204 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NEPIEIGG_02140 1.45e-231 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NEPIEIGG_02141 2.06e-196 - - - IQ - - - Oxidoreductase, short chain dehydrogenase reductase family protein
NEPIEIGG_02142 4.13e-38 - - - C - - - Oxidoreductase, FAD FMN-binding protein
NEPIEIGG_02148 1.4e-260 - - - G - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02149 6.96e-240 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_02150 3.06e-115 - 6.4.1.1 - I ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Biotin-requiring enzyme
NEPIEIGG_02151 0.0 accC 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K01961,ko:K01965 ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
NEPIEIGG_02152 3.89e-306 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_02153 0.0 mexF - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NEPIEIGG_02154 2.23e-163 mtrC - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEPIEIGG_02155 7.23e-193 - - - S - - - Protein of unknown function (DUF2961)
NEPIEIGG_02156 1.57e-112 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_02159 8.51e-287 - 3.2.1.20 GH31 M ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl-hydrolase 97 C-terminal, oligomerisation
NEPIEIGG_02162 6.68e-103 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NEPIEIGG_02163 1.63e-284 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit
NEPIEIGG_02164 1.44e-169 - - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NEPIEIGG_02165 2.12e-70 amyA2 - - G - - - Alpha amylase, catalytic domain
NEPIEIGG_02166 0.0 amyA2 - - G - - - Alpha amylase, catalytic domain
NEPIEIGG_02167 5.07e-41 - - - - - - - -
NEPIEIGG_02168 1.55e-264 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEPIEIGG_02169 1.11e-299 nhaA - - P ko:K03313 - ko00000,ko02000 ) H( ) antiporter that extrudes sodium in exchange for external protons
NEPIEIGG_02170 1.4e-129 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_02171 1.73e-242 - - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
NEPIEIGG_02172 1.96e-141 cstA - - T ko:K06200 - ko00000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02173 1.23e-43 - - - S - - - COG NOG34202 non supervised orthologous group
NEPIEIGG_02174 2.28e-117 - - - MU - - - COG NOG29365 non supervised orthologous group
NEPIEIGG_02175 5.7e-63 higA - - K ko:K21498 - ko00000,ko02048 addiction module antidote protein, HigA
NEPIEIGG_02176 8.2e-68 - - - S ko:K07334 - ko00000,ko02048 Plasmid maintenance system killer protein
NEPIEIGG_02178 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NEPIEIGG_02179 6.45e-163 - - - - - - - -
NEPIEIGG_02180 2.25e-57 - - - C - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02181 1.31e-223 - - - G - - - Glycosyl hydrolase family 92
NEPIEIGG_02182 1.76e-30 bpeF - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NEPIEIGG_02183 1.15e-64 per1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 COG2367 Beta-lactamase class A
NEPIEIGG_02184 4.82e-116 per1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 COG2367 Beta-lactamase class A
NEPIEIGG_02185 7.87e-105 - - - V - - - COG NOG14438 non supervised orthologous group
NEPIEIGG_02186 8.08e-188 amn 3.2.2.4 - F ko:K01241 ko00230,map00230 ko00000,ko00001,ko01000 COG COG0775 Nucleoside phosphorylase
NEPIEIGG_02187 1.88e-38 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 COG1466 DNA polymerase III, delta subunit
NEPIEIGG_02189 1.26e-203 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02190 8.1e-110 - - - I - - - lipid kinase, YegS Rv2252 BmrU family
NEPIEIGG_02191 7.11e-317 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NEPIEIGG_02192 3.07e-53 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NEPIEIGG_02193 1.84e-83 - - - S - - - Psort location CytoplasmicMembrane, score 9.46
NEPIEIGG_02194 5.02e-89 - 3.5.1.53 - S ko:K12251 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 hydrolase, carbon-nitrogen family
NEPIEIGG_02195 0.0 - - - H - - - Psort location OuterMembrane, score
NEPIEIGG_02197 3.9e-303 rnfC - - C ko:K03615 - ko00000 Part of a membrane complex involved in electron transport
NEPIEIGG_02198 1.43e-170 rnfB - - C ko:K03616 - ko00000 electron transport complex, RnfABCDGE type, B subunit
NEPIEIGG_02201 1.1e-229 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
NEPIEIGG_02203 0.0 - - - G - - - Alpha-1,2-mannosidase
NEPIEIGG_02204 1.34e-138 - 1.1.1.367 - GM ko:K19068 - ko00000,ko01000 NAD dependent epimerase dehydratase family
NEPIEIGG_02205 4.73e-287 - 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 UDP-N-acetylglucosamine 2-epimerase
NEPIEIGG_02206 2.52e-304 - - GT4 M ko:K03208 - ko00000 Glycosyltransferase, group 1 family protein
NEPIEIGG_02207 0.0 - - - P - - - TonB dependent receptor
NEPIEIGG_02208 3.58e-265 - - - GM ko:K21572 - ko00000,ko02000 Pfam:SusD
NEPIEIGG_02209 8.86e-195 yicJ_1 - - G ko:K03292 - ko00000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02210 1.48e-293 bfce 5.1.3.11 - G ko:K16213 - ko00000,ko01000 Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)
NEPIEIGG_02211 1.46e-197 - - - S - - - GDSL-like Lipase/Acylhydrolase
NEPIEIGG_02212 5.71e-39 - 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NEPIEIGG_02214 0.0 dbpA 3.6.4.13 - L ko:K05591 - ko00000,ko01000,ko03009 ATP-independent RNA helicase DbpA
NEPIEIGG_02215 2.75e-244 - 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Carbohydrate binding domain protein
NEPIEIGG_02217 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_02219 9.4e-175 - - - M - - - Glycosyl transferases group 1
NEPIEIGG_02220 1.01e-207 - - - M - - - Psort location Cytoplasmic, score
NEPIEIGG_02221 0.0 - - - M - - - Belongs to the glycosyl hydrolase 28 family
NEPIEIGG_02222 0.0 - - - S - - - Serine hydrolase involved in the detoxification of formaldehyde
NEPIEIGG_02223 3.94e-260 rfaE 2.7.1.167, 2.7.7.70 - H ko:K03272 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NEPIEIGG_02224 1.88e-116 gmhB 3.1.3.82, 3.1.3.83 - E ko:K03273 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Polynucleotide kinase 3 phosphatase
NEPIEIGG_02225 2.01e-133 gmhA 5.3.1.28 - G ko:K03271 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate
NEPIEIGG_02226 1.76e-182 - - - T - - - Lipopolysaccharide kinase (Kdo/WaaP) family
NEPIEIGG_02227 7.87e-149 - - - G - - - Cellulase N-terminal ig-like domain
NEPIEIGG_02228 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NEPIEIGG_02229 4.89e-20 - - - - - - - -
NEPIEIGG_02230 3.1e-79 - - - S - - - Protein of unknown function (DUF3795)
NEPIEIGG_02232 3.87e-20 - - - L - - - DNA primase
NEPIEIGG_02233 1.67e-85 - - - L - - - DNA primase
NEPIEIGG_02236 9.68e-134 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NEPIEIGG_02237 3.71e-49 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
NEPIEIGG_02238 2.23e-150 spk1 2.7.11.1, 6.3.2.4 - S ko:K01921,ko:K08884,ko:K12132 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01001,ko01011 PASTA domain protein
NEPIEIGG_02239 1.07e-234 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NEPIEIGG_02240 4.88e-200 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
NEPIEIGG_02243 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_02244 0.0 - - - P ko:K16089 - ko00000,ko02000 COG4771 Outer membrane receptor for ferrienterochelin and colicins
NEPIEIGG_02245 0.0 - - - GM ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_02246 4.99e-264 lacZ_17 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
NEPIEIGG_02247 1.91e-267 - - - MU - - - COG NOG26656 non supervised orthologous group
NEPIEIGG_02248 1.29e-203 - - - M ko:K01993 - ko00000 COG COG0845 Membrane-fusion protein
NEPIEIGG_02252 2.67e-179 lipB 3.1.4.55 - S ko:K06167 ko00440,map00440 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_02253 2.35e-184 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
NEPIEIGG_02254 4.99e-156 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NEPIEIGG_02255 2.83e-236 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02256 1.18e-104 yqaA - - S - - - Psort location CytoplasmicMembrane, score 9.46
NEPIEIGG_02257 2.05e-164 mnmC - - S - - - Psort location Cytoplasmic, score
NEPIEIGG_02258 2.4e-189 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_02260 0.0 - - - S - - - Tetratricopeptide repeat protein
NEPIEIGG_02261 5.39e-38 oadB 4.1.1.3 - C ko:K01572 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 sodium ion-translocating decarboxylase, beta subunit
NEPIEIGG_02263 4.56e-115 - - - S - - - COG NOG29882 non supervised orthologous group
NEPIEIGG_02264 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NEPIEIGG_02265 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
NEPIEIGG_02266 5.79e-101 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
NEPIEIGG_02268 0.0 metZ 2.5.1.49 - E ko:K01740,ko:K10764 ko00270,ko00920,ko01100,map00270,map00920,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_02269 1.29e-123 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain protein
NEPIEIGG_02270 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 9.97
NEPIEIGG_02272 8.83e-66 - - - V ko:K02004 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02273 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02275 2.11e-193 dapL 2.6.1.83 - H ko:K10206 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate
NEPIEIGG_02276 2.7e-173 - - - S - - - Psort location OuterMembrane, score 9.52
NEPIEIGG_02277 6.12e-76 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
NEPIEIGG_02280 7.5e-57 - - - - - - - -
NEPIEIGG_02281 0.0 - - - P ko:K16089 - ko00000,ko02000 COG4771 Outer membrane receptor for ferrienterochelin and colicins
NEPIEIGG_02282 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_02284 0.0 cca 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 tRNA nucleotidyltransferase poly(A) polymerase
NEPIEIGG_02285 9.48e-189 - - - U - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02286 1.97e-137 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NEPIEIGG_02287 0.0 - - - S - - - COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NEPIEIGG_02288 5.25e-80 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_02291 1.85e-143 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_02292 1.5e-64 - - - S - - - Stress responsive A B barrel domain
NEPIEIGG_02293 5.85e-110 kdsB 2.7.7.38 - H ko:K00979 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NEPIEIGG_02294 1.09e-310 - - - S - - - Peptidase M16 inactive domain
NEPIEIGG_02297 4.22e-76 - - - S - - - COG NOG29451 non supervised orthologous group
NEPIEIGG_02298 2.26e-64 - - - Q - - - Esterase PHB depolymerase
NEPIEIGG_02299 3.47e-48 - - - T - - - COG0642 Signal transduction histidine kinase
NEPIEIGG_02300 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
NEPIEIGG_02301 2.55e-44 - - - S - - - COG NOG19145 non supervised orthologous group
NEPIEIGG_02302 1.51e-260 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02303 1.65e-205 - - - IQ - - - Oxidoreductase, short chain dehydrogenase reductase family protein
NEPIEIGG_02304 1.5e-176 - - - T - - - Carbohydrate-binding family 9
NEPIEIGG_02305 2.08e-264 mdsC - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02307 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_02308 3.72e-255 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEPIEIGG_02309 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 glycosyl hydrolase, family 3
NEPIEIGG_02310 1.99e-200 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase middle domain
NEPIEIGG_02311 1.58e-116 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase middle domain
NEPIEIGG_02312 9.48e-300 aprN - - M - - - Belongs to the peptidase S8 family
NEPIEIGG_02313 3.31e-137 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NEPIEIGG_02318 0.0 - - - U - - - WD40-like Beta Propeller Repeat
NEPIEIGG_02319 2.53e-229 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02322 0.0 - - - V - - - Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NEPIEIGG_02323 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
NEPIEIGG_02324 2.56e-108 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
NEPIEIGG_02325 1.04e-59 - - - S - - - Tetratricopeptide repeat protein
NEPIEIGG_02326 2.57e-37 oorD 1.2.7.3 - C ko:K00176 ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200 br01601,ko00000,ko00001,ko00002,ko01000 4Fe-4S binding domain protein
NEPIEIGG_02328 5.94e-122 nqrE 1.6.5.8 - C ko:K00350 - ko00000,ko01000 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NEPIEIGG_02329 1.31e-142 nqrD 1.6.5.8 - C ko:K00349 - ko00000,ko01000 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NEPIEIGG_02331 0.0 xynBA - - G - - - Belongs to the glycosyl hydrolase 43 family
NEPIEIGG_02332 9.18e-123 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl-hydrolase 97 C-terminal, oligomerisation
NEPIEIGG_02333 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NEPIEIGG_02334 3.48e-16 - - - - - - - -
NEPIEIGG_02335 0.0 - - - D ko:K09955 - ko00000 protein conserved in bacteria
NEPIEIGG_02337 1e-66 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NEPIEIGG_02338 1.06e-162 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NEPIEIGG_02342 7.19e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NEPIEIGG_02343 8.71e-39 - - - L - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02345 2.08e-144 - - - K ko:K07735 - ko00000,ko03000 Belongs to the UPF0301 (AlgH) family
NEPIEIGG_02346 7.38e-127 speG 2.3.1.57 - J ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 Acetyltransferase, gnat family
NEPIEIGG_02347 1.18e-84 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_02348 7.44e-261 - - - H - - - COG NOG08812 non supervised orthologous group
NEPIEIGG_02350 5.17e-250 - - - S - - - Endonuclease Exonuclease phosphatase family
NEPIEIGG_02351 7.19e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NEPIEIGG_02352 0.0 glnA 6.3.1.2 - S ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 Glutamate--ammonia ligase, catalytic domain protein
NEPIEIGG_02353 7.44e-206 - - - K ko:K13652 - ko00000,ko03000 methylphosphotriester-DNA alkyltransferase (AraC XylS family)
NEPIEIGG_02354 7.2e-175 - - - L - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02355 7.08e-84 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NEPIEIGG_02356 9.01e-192 tig - - O ko:K03545 - ko00000 peptidyl-prolyl cis-trans isomerase (trigger factor)
NEPIEIGG_02357 5.04e-154 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NEPIEIGG_02362 2.32e-100 - - - S - - - COG NOG19145 non supervised orthologous group
NEPIEIGG_02363 1.16e-241 pheB 5.4.99.5 - E ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_02364 1.86e-286 dapL 2.6.1.83 - E ko:K10206,ko:K14261 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 COG0436 Aspartate tyrosine aromatic aminotransferase
NEPIEIGG_02365 1.81e-103 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02366 1.36e-210 - - - S - - - AAA ATPase domain
NEPIEIGG_02368 0.0 yngK - - S - - - lipoprotein YddW precursor K01189
NEPIEIGG_02369 9.31e-136 - - - S - - - Psort location Cytoplasmic, score
NEPIEIGG_02370 1.93e-136 - 3.1.2.12 CE1 S ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 ko00000,ko00001,ko01000 esterase
NEPIEIGG_02371 1.32e-291 corC_1 - - P ko:K03699 - ko00000,ko02042 Psort location CytoplasmicMembrane, score
NEPIEIGG_02372 1.38e-103 - - - MP ko:K06079 ko01503,map01503 ko00000,ko00001 COG NOG29769 non supervised orthologous group
NEPIEIGG_02373 3.46e-151 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
NEPIEIGG_02374 6.47e-208 - - - S - - - COG NOG24904 non supervised orthologous group
NEPIEIGG_02375 3.72e-261 - - - P - - - phosphate-selective porin
NEPIEIGG_02377 2.96e-111 aglC 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 COG3345 Alpha-galactosidase
NEPIEIGG_02380 0.0 otsB 2.4.1.15, 3.1.3.12 GT20 G ko:K16055 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000,ko01003 Trehalose-phosphatase
NEPIEIGG_02381 5.57e-227 - - - G - - - Kinase, PfkB family
NEPIEIGG_02384 4.25e-82 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NEPIEIGG_02385 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 9.26
NEPIEIGG_02387 0.0 lysM - - M - - - LysM domain
NEPIEIGG_02388 8.7e-104 - - - S - - - Putative glucoamylase
NEPIEIGG_02389 1.47e-207 - - - S - - - Endonuclease Exonuclease phosphatase family
NEPIEIGG_02392 6.35e-262 lacZ 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 COG3250 Beta-galactosidase beta-glucuronidase
NEPIEIGG_02393 7.34e-140 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG COG2818 3-methyladenine DNA glycosylase
NEPIEIGG_02396 2.34e-85 - - - K - - - Helix-turn-helix domain
NEPIEIGG_02397 1.54e-187 - - - - - - - -
NEPIEIGG_02398 1.55e-134 - - - S - - - protein (some members contain a von Willebrand factor type A (vWA) domain)
NEPIEIGG_02399 1.6e-247 - - - O - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_02401 2.51e-296 yccM - - C - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_02402 4.59e-273 - 3.2.1.3 GH15 G ko:K01178 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolases family 15
NEPIEIGG_02403 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NEPIEIGG_02404 1.44e-112 ybaK - - H ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NEPIEIGG_02405 7.99e-200 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NEPIEIGG_02406 4.68e-185 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
NEPIEIGG_02407 4.9e-140 - - - L - - - Domain of unknown function (DUF4373)
NEPIEIGG_02408 9.53e-161 - - - S - - - Calcineurin-like phosphoesterase
NEPIEIGG_02409 4.15e-204 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NEPIEIGG_02410 5.99e-268 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NEPIEIGG_02411 5.09e-41 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEPIEIGG_02412 7.72e-81 - - - M - - - Glycosyl hydrolases family 25
NEPIEIGG_02413 2.02e-221 - - - E - - - Domain of unknown function (DUF4374)
NEPIEIGG_02414 1.59e-287 piuB - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_02416 2.18e-213 - - - S - - - COG NOG26673 non supervised orthologous group
NEPIEIGG_02417 7.03e-193 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family
NEPIEIGG_02418 1.09e-157 yhgF - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain
NEPIEIGG_02419 1.15e-207 - - - M - - - Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEPIEIGG_02420 4.28e-125 - - - K ko:K03088 - ko00000,ko03021 Sigma-70, region 4
NEPIEIGG_02421 8.05e-167 - - - S - - - COG NOG31568 non supervised orthologous group
NEPIEIGG_02423 1.7e-77 rnfG - - C ko:K03612 - ko00000 Part of a membrane complex involved in electron transport
NEPIEIGG_02424 8.98e-122 rnfE - - C ko:K03613 - ko00000 Part of a membrane complex involved in electron transport
NEPIEIGG_02425 1.39e-120 rnfA - - C ko:K03617 - ko00000 Part of a membrane complex involved in electron transport
NEPIEIGG_02427 6.21e-156 - - - P - - - Psort location OuterMembrane, score 9.52
NEPIEIGG_02428 0.0 - - - P - - - Psort location OuterMembrane, score 9.52
NEPIEIGG_02429 0.0 - - - S ko:K06158 - ko00000,ko03012 Psort location CytoplasmicMembrane, score
NEPIEIGG_02430 1.48e-90 divK - - T - - - Response regulator receiver domain protein
NEPIEIGG_02431 2.64e-62 - - - - - - - -
NEPIEIGG_02432 2.1e-179 - - - E - - - Belongs to the DegT DnrJ EryC1 family
NEPIEIGG_02433 1.19e-77 wbpD 2.3.1.201 - M ko:K13018 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Bacterial transferase hexapeptide
NEPIEIGG_02434 1.59e-80 - 1.1.1.335 - S ko:K13020 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Oxidoreductase family, C-terminal alpha beta domain
NEPIEIGG_02435 1.34e-116 uxuB - - IQ - - - Oxidoreductase, short chain dehydrogenase reductase family protein
NEPIEIGG_02436 3.09e-288 uxuA 4.2.1.8 - H ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
NEPIEIGG_02437 8.77e-144 aqpZ - - G ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NEPIEIGG_02441 0.0 - - - G - - - Belongs to the glycosyl hydrolase 43 family
NEPIEIGG_02442 1.28e-101 - - - P ko:K01138 - ko00000,ko01000 COG COG3119 Arylsulfatase A and related enzymes
NEPIEIGG_02443 2.31e-27 - - - G ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEPIEIGG_02444 6.84e-237 ybhS - - V ko:K01992 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02445 4.32e-258 - - - V ko:K01992 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02446 2.02e-126 - 2.7.7.7 - L ko:K02334 - ko00000,ko01000 DNA polymerase
NEPIEIGG_02447 1.05e-93 - - - S - - - Protein of unknown function (DUF2815)
NEPIEIGG_02448 3.55e-86 - - - L - - - Protein of unknown function (DUF2800)
NEPIEIGG_02449 2.51e-282 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_02450 1.28e-167 - - - T - - - Response regulator receiver domain
NEPIEIGG_02452 2.42e-285 nspC 4.1.1.96 - E ko:K13747 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_02453 3.29e-80 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NEPIEIGG_02454 1.79e-145 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NEPIEIGG_02455 1.29e-66 - - - S - - - Protein kinase domain
NEPIEIGG_02457 0.0 - 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
NEPIEIGG_02458 1.95e-97 dapH - - S - - - Bacterial transferase hexapeptide repeat protein
NEPIEIGG_02459 6.34e-84 waaA 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 M ko:K02527 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Psort location Cytoplasmic, score 8.96
NEPIEIGG_02460 8.54e-36 - - - S ko:K21571 - ko00000 Outer membrane protein SusF_SusE
NEPIEIGG_02461 0.0 - 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 COG NOG34737 non supervised orthologous group
NEPIEIGG_02463 1.11e-187 - 1.1.1.29 - CH ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NEPIEIGG_02466 3.84e-241 - - - S ko:K07137 - ko00000 FAD-dependent
NEPIEIGG_02467 0.0 leuA_1 2.3.1.182 - E ko:K09011 ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the alpha-IPM synthase homocitrate synthase family
NEPIEIGG_02468 9.7e-56 - - - - - - - -
NEPIEIGG_02470 6.45e-90 - - - K - - - Helix-turn-helix XRE-family like proteins
NEPIEIGG_02471 2.48e-271 - - - O - - - COG NOG14454 non supervised orthologous group
NEPIEIGG_02472 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
NEPIEIGG_02473 1.38e-75 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_02474 3.48e-303 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NEPIEIGG_02475 2.12e-95 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NEPIEIGG_02476 4.97e-86 - - - S - - - COG NOG31702 non supervised orthologous group
NEPIEIGG_02477 2.19e-117 - - - S - - - COG NOG27987 non supervised orthologous group
NEPIEIGG_02478 5.96e-132 mutS_2 - - L - - - DNA mismatch repair protein MutS
NEPIEIGG_02480 1.05e-89 - - - S - - - Protein of unknown function DUF262
NEPIEIGG_02481 1.78e-222 - - - T - - - Clostripain family
NEPIEIGG_02482 1.25e-38 - - - L ko:K07480 - ko00000 PFAM IS1 transposase
NEPIEIGG_02484 1.02e-38 - - - - - - - -
NEPIEIGG_02485 1.79e-213 serA 1.1.1.399, 1.1.1.95 - C ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEPIEIGG_02486 1.54e-214 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NEPIEIGG_02488 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02489 1.1e-313 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Psort location Cytoplasmic, score
NEPIEIGG_02490 1.56e-262 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NEPIEIGG_02491 1.75e-129 - - - C - - - 4Fe-4S binding domain protein
NEPIEIGG_02492 8.91e-121 paiA - - K - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02493 9.42e-261 - - - P ko:K03305 - ko00000 amino acid peptide transporter
NEPIEIGG_02494 1.45e-160 - - - S - - - Sporulation and cell division repeat protein
NEPIEIGG_02495 3.42e-124 - - - T - - - FHA domain protein
NEPIEIGG_02496 1.05e-252 uxaB 1.1.1.17, 1.1.1.58 - C ko:K00009,ko:K00041 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the mannitol dehydrogenase family. UxaB subfamily
NEPIEIGG_02497 6.15e-79 - - - K - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02498 1.62e-65 - - - K - - - stress protein (general stress protein 26)
NEPIEIGG_02499 3.96e-120 - - - S - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_02500 1.86e-48 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02501 8.34e-35 - - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
NEPIEIGG_02502 1.6e-145 - - - JM - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02503 1.41e-39 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
NEPIEIGG_02504 0.0 - - - S - - - COG NOG11656 non supervised orthologous group
NEPIEIGG_02505 5.63e-97 - - - O - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_02506 1.89e-224 cepA 2.4.1.20 GT36 G ko:K00702 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Putative carbohydrate binding domain
NEPIEIGG_02507 1.54e-246 gpr - - C ko:K19265 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
NEPIEIGG_02508 2.36e-229 gluP - - G ko:K02429 - ko00000,ko02000 Transporter, major facilitator family protein
NEPIEIGG_02509 3.58e-284 galK 2.7.1.6 - H ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family. GalK subfamily
NEPIEIGG_02511 2.49e-47 - - - O - - - Belongs to the sulfur carrier protein TusA family
NEPIEIGG_02512 1.08e-67 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02513 1.14e-65 xly - - M - - - fibronectin type III domain protein
NEPIEIGG_02514 0.0 - - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 DNA mismatch repair protein
NEPIEIGG_02515 7.3e-168 - - - K ko:K02081 - ko00000,ko03000 DeoR C terminal sensor domain
NEPIEIGG_02516 3e-162 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Psort location Cytoplasmic, score
NEPIEIGG_02517 2.74e-118 - - - S - - - COG NOG27649 non supervised orthologous group
NEPIEIGG_02518 4.7e-108 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NEPIEIGG_02519 2.71e-65 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NEPIEIGG_02520 1.58e-83 - - - S ko:K21572 - ko00000,ko02000 COG NOG25802 non supervised orthologous group
NEPIEIGG_02522 6.67e-237 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NEPIEIGG_02523 5.33e-210 - - - S - - - Domain of unknown function (DUF4886)
NEPIEIGG_02524 0.0 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_02525 0.0 - - - S - - - candidate xyloglucanase, glycoside hydrolase family 74 protein K01238
NEPIEIGG_02526 1.06e-126 anmK 2.7.1.170 - F ko:K09001 - ko00000,ko01000 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NEPIEIGG_02527 1.01e-133 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_02528 2.12e-159 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 COG0550 Topoisomerase IA
NEPIEIGG_02529 3.15e-100 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 COG0550 Topoisomerase IA
NEPIEIGG_02530 4.43e-166 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 COG0010 Arginase agmatinase formimionoglutamate hydrolase arginase family
NEPIEIGG_02531 2.8e-88 - - - L - - - DDE superfamily endonuclease
NEPIEIGG_02532 8.29e-198 dcp 3.4.15.5 - E ko:K01284 - ko00000,ko01000,ko01002 Peptidase family M3
NEPIEIGG_02533 1.89e-257 - - - L - - - Endonuclease Exonuclease phosphatase family
NEPIEIGG_02534 4.6e-27 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02535 1.86e-50 fabG_2 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
NEPIEIGG_02536 5.15e-315 - - - IQ - - - AMP-binding enzyme
NEPIEIGG_02537 2.11e-49 - - - IQ - - - Carrier of the growing fatty acid chain in fatty acid biosynthesis
NEPIEIGG_02538 6.27e-75 - - - - - - - -
NEPIEIGG_02540 6.93e-72 - - - L - - - DNA photolyase activity
NEPIEIGG_02541 2.12e-42 - - - L - - - DNA photolyase activity
NEPIEIGG_02542 1.67e-146 - - - S - - - VirE N-terminal domain
NEPIEIGG_02543 1.61e-142 - - - - - - - -
NEPIEIGG_02544 6.41e-172 znuC - - P ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NEPIEIGG_02545 1.47e-171 mntA - - P ko:K09815,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0803 ABC-type metal ion transport system, periplasmic component surface adhesin
NEPIEIGG_02546 2.34e-69 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NEPIEIGG_02547 4.64e-155 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 uracil phosphoribosyltransferase
NEPIEIGG_02548 5.73e-119 - - - - - - - -
NEPIEIGG_02550 0.0 - - - I - - - Psort location OuterMembrane, score
NEPIEIGG_02551 2.14e-52 - - - - - - - -
NEPIEIGG_02552 0.0 - - - - - - - -
NEPIEIGG_02553 1.13e-180 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEPIEIGG_02555 4e-14 - - - S - - - Toxin-antitoxin system, antitoxin component, HicB family
NEPIEIGG_02556 1.44e-19 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02557 2.07e-28 - - - - - - - -
NEPIEIGG_02558 1.05e-172 cypM_1 - - H - - - Methyltransferase domain protein
NEPIEIGG_02559 6.37e-125 - - - CO - - - Redoxin family
NEPIEIGG_02561 1.45e-46 - - - - - - - -
NEPIEIGG_02562 3.89e-89 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
NEPIEIGG_02563 1.09e-55 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NEPIEIGG_02564 0.0 - 6.4.1.1 - C ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG5016 Pyruvate oxaloacetate carboxyltransferase
NEPIEIGG_02572 0.0 - 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NEPIEIGG_02573 0.0 fusA2 - - J ko:K02355 - ko00000,ko03012,ko03029 Psort location Cytoplasmic, score 9.26
NEPIEIGG_02574 8.23e-269 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NEPIEIGG_02575 3.28e-144 - - - V - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02576 9.51e-194 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Psort location Cytoplasmic, score 9.97
NEPIEIGG_02577 3.85e-103 - - - S - - - COG NOG16874 non supervised orthologous group
NEPIEIGG_02578 2.09e-41 - - - S - - - COG NOG33517 non supervised orthologous group
NEPIEIGG_02579 3.57e-76 mmdC - - I - - - first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NEPIEIGG_02580 1.56e-222 - - - C - - - COG NOG19100 non supervised orthologous group
NEPIEIGG_02581 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NEPIEIGG_02583 0.0 - - - S - - - protein conserved in bacteria
NEPIEIGG_02584 7.11e-122 - - - S - - - Endonuclease Exonuclease phosphatase family
NEPIEIGG_02585 5.84e-86 - - - L - - - Domain of unknown function (DUF4357)
NEPIEIGG_02586 1.08e-24 - - - L - - - DDE superfamily endonuclease
NEPIEIGG_02587 2.07e-155 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NEPIEIGG_02588 1.64e-108 - - - G - - - Cupin 2, conserved barrel domain protein
NEPIEIGG_02589 2.08e-77 - - - K - - - Transcription termination antitermination factor NusG
NEPIEIGG_02590 5.45e-160 - - - M - - - Chain length determinant protein
NEPIEIGG_02591 6.89e-225 - - - - - - - -
NEPIEIGG_02592 1.12e-24 - - - - - - - -
NEPIEIGG_02593 9.82e-92 - - - - - - - -
NEPIEIGG_02594 1.84e-39 - 6.3.5.5 - S ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 ATP-grasp in the biosynthetic pathway with Ter operon
NEPIEIGG_02595 2.16e-147 pseI 2.5.1.56, 2.5.1.97 - H ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 COG2089 Sialic acid synthase
NEPIEIGG_02597 5.08e-136 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NEPIEIGG_02598 3.52e-161 - - - - - - - -
NEPIEIGG_02599 9.24e-152 - - - S - - - Conserved protein
NEPIEIGG_02600 4.08e-53 - - - - - - - -
NEPIEIGG_02601 2.11e-97 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
NEPIEIGG_02602 8.74e-55 - - - S - - - Psort location CytoplasmicMembrane, score 9.46
NEPIEIGG_02605 1.94e-127 - - - K - - - Cupin domain protein
NEPIEIGG_02606 9.45e-93 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NEPIEIGG_02607 3.98e-66 - - - S - - - polysaccharide biosynthetic process
NEPIEIGG_02609 1.03e-207 lspL 5.1.3.6 - M ko:K08679 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 epimerase dehydratase
NEPIEIGG_02611 2.15e-132 - - - C ko:K02120 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Psort location Cytoplasmic, score 8.96
NEPIEIGG_02612 2.74e-90 ntpB - - C ko:K02118 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 ATP synthase alpha beta family, nucleotide-binding domain protein
NEPIEIGG_02613 9.64e-31 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NEPIEIGG_02614 6.83e-236 cysK 2.5.1.47 - E ko:K01738,ko:K12339 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NEPIEIGG_02617 0.0 zraR_2 - - T - - - COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
NEPIEIGG_02620 5.55e-167 dcp 3.4.15.5 - E ko:K01284 - ko00000,ko01000,ko01002 Peptidase family M3
NEPIEIGG_02621 4.55e-143 - - - M - - - Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NEPIEIGG_02622 3.77e-165 comF 2.4.2.14 - S ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 ComF family
NEPIEIGG_02623 8.76e-160 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_02624 6.57e-19 - - - G - - - COGs COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NEPIEIGG_02625 1.4e-238 - - - G - - - Glycosyl hydrolases family 43
NEPIEIGG_02626 5.57e-90 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Pyridoxal kinase
NEPIEIGG_02627 1.1e-190 - - - G - - - COG COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NEPIEIGG_02628 1.18e-76 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 Psort location Cytoplasmic, score
NEPIEIGG_02629 9.4e-133 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NEPIEIGG_02632 3.08e-44 - - - - - - - -
NEPIEIGG_02634 5.26e-179 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG COG1022 Long-chain acyl-CoA synthetases (AMP-forming)
NEPIEIGG_02635 2.49e-261 susB 3.2.1.20, 3.2.1.3 GH31,GH97 G ko:K01187,ko:K21574 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG NOG06228 non supervised orthologous group
NEPIEIGG_02636 7.03e-38 - 3.4.13.19 - E ko:K01273,ko:K01274 - ko00000,ko00537,ko01000,ko01002,ko04147 Renal dipeptidase family protein
NEPIEIGG_02637 1.09e-42 - - - S - - - Winged helix-turn-helix domain (DUF2582)
NEPIEIGG_02638 4.54e-95 - - - J - - - Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NEPIEIGG_02639 6.01e-224 trkA - - C ko:K03499 - ko00000,ko02000 COG0569 K transport systems NAD-binding component
NEPIEIGG_02641 7.6e-105 - - - S - - - GGGtGRT protein
NEPIEIGG_02642 3.55e-67 - - - S ko:K18843 - ko00000,ko02048 HicB family
NEPIEIGG_02643 2.23e-33 - - - S - - - HicA toxin of bacterial toxin-antitoxin,
NEPIEIGG_02644 6.44e-22 - - - S - - - Domain of unknown function (DUF4397)
NEPIEIGG_02645 7.22e-137 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NEPIEIGG_02646 2.71e-185 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 COG0847 DNA polymerase III epsilon subunit and related 3'-5'
NEPIEIGG_02647 1.91e-73 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEPIEIGG_02648 9.28e-89 - - - S - - - Lipocalin-like domain
NEPIEIGG_02649 3.92e-37 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEPIEIGG_02650 1.62e-255 ilvE 2.6.1.42 - EH ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase
NEPIEIGG_02651 1.05e-181 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_02657 6.73e-217 - - - S ko:K01992 - ko00000,ko00002,ko02000 COG COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NEPIEIGG_02658 6.19e-168 yxlF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 Psort location Cytoplasmic, score 9.12
NEPIEIGG_02659 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NEPIEIGG_02660 5.06e-72 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NEPIEIGG_02661 2.09e-289 - - - T - - - COG COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases
NEPIEIGG_02662 1.84e-227 - - - J ko:K21572 - ko00000,ko02000 Pfam:SusD
NEPIEIGG_02664 0.0 - - - G - - - beta-fructofuranosidase activity
NEPIEIGG_02666 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_02667 4.91e-110 - - - S ko:K21572 - ko00000,ko02000 SusD family
NEPIEIGG_02668 3.5e-126 - - - S - - - COG NOG35345 non supervised orthologous group
NEPIEIGG_02669 1.3e-207 fabD 2.3.1.39 - I ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 malonyl CoA-acyl carrier protein transacylase
NEPIEIGG_02670 5.46e-108 - - - J - - - Threonine alanine tRNA ligase second additional domain protein
NEPIEIGG_02671 2.01e-99 hsp20 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NEPIEIGG_02672 1.2e-74 - - - I - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02673 1.97e-58 - - - I - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02674 2.97e-232 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
NEPIEIGG_02678 3.92e-197 - - - P - - - Psort location OuterMembrane, score
NEPIEIGG_02679 3.29e-298 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NEPIEIGG_02681 3.78e-167 mlaE - - Q ko:K02066 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02682 1.39e-195 lptB - - S ko:K06861 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Psort location Cytoplasmic, score 9.12
NEPIEIGG_02683 8.79e-210 - - - M - - - tail specific protease
NEPIEIGG_02685 1.27e-19 - - - S - - - Protein of unknown function (DUF2961)
NEPIEIGG_02687 0.0 susB 3.2.1.20, 3.2.1.3 GH31,GH97 G ko:K01187,ko:K21574 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl-hydrolase 97 C-terminal, oligomerisation
NEPIEIGG_02689 4.7e-198 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 protein contains double-stranded beta-helix domain
NEPIEIGG_02690 0.0 - 3.2.1.31 - G ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolases family 2, TIM barrel domain
NEPIEIGG_02692 2.91e-146 - - - J - - - Domain of unknown function (DUF4476)
NEPIEIGG_02699 4.32e-110 msrC 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
NEPIEIGG_02700 1.3e-209 - - - EG ko:K08978 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02701 3.39e-51 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NEPIEIGG_02702 4.54e-54 - - - S - - - Domain of unknown function (DUF4248)
NEPIEIGG_02703 5.12e-237 - - - S - - - P-loop ATPase and inactivated derivatives
NEPIEIGG_02704 4.92e-150 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase, glutamine-hydrolyzing
NEPIEIGG_02705 3.15e-06 - - - - - - - -
NEPIEIGG_02706 2.34e-108 - - - L - - - COG NOG29624 non supervised orthologous group
NEPIEIGG_02707 3.22e-68 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NEPIEIGG_02708 0.0 cbiA 6.3.5.11, 6.3.5.9 - H ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
NEPIEIGG_02709 1.7e-145 mtnN 3.2.2.9 - F ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NEPIEIGG_02710 1.48e-118 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NEPIEIGG_02711 2.46e-165 - - - IQ ko:K00666 - ko00000,ko01000,ko01004 Psort location Cytoplasmic, score 9.97
NEPIEIGG_02712 3.41e-167 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 COG COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
NEPIEIGG_02713 1.88e-112 - 3.1.1.85 - S ko:K09789 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Protein of unknown function (DUF452)
NEPIEIGG_02714 6.77e-122 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NEPIEIGG_02715 7.6e-269 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NEPIEIGG_02716 5.07e-158 lipB 2.3.1.181 - H ko:K03801 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate
NEPIEIGG_02717 8.55e-137 acpH - - S - - - Acyl carrier protein phosphodiesterase
NEPIEIGG_02718 5.35e-36 - - - L - - - COG NOG19076 non supervised orthologous group
NEPIEIGG_02719 6.95e-202 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
NEPIEIGG_02720 1.08e-59 - - - L - - - regulation of translation
NEPIEIGG_02722 1.5e-256 - - - L - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02725 6.58e-62 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NEPIEIGG_02726 0.0 leuC 4.2.1.33, 4.2.1.35 - H ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NEPIEIGG_02728 2e-142 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NEPIEIGG_02729 3.51e-141 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NEPIEIGG_02730 9.66e-160 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NEPIEIGG_02732 1.94e-117 - - - - - - - -
NEPIEIGG_02733 2.16e-163 - - - - - - - -
NEPIEIGG_02734 1.47e-237 hpaIIR 3.1.21.4 - L ko:K01155 - ko00000,ko01000,ko02048 COG NOG26934 non supervised orthologous group
NEPIEIGG_02735 4.81e-138 - - - C - - - Nitroreductase family
NEPIEIGG_02736 7.84e-31 - - - P - - - Psort location OuterMembrane, score 9.52
NEPIEIGG_02739 1.54e-224 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NEPIEIGG_02740 2.47e-107 - - - L - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02741 2.76e-175 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NEPIEIGG_02742 1.62e-49 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
NEPIEIGG_02744 3.29e-186 - - - S - - - COG NOG27381 non supervised orthologous group
NEPIEIGG_02745 2.76e-39 - - - S - - - COG COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NEPIEIGG_02746 4.48e-301 - - - G - - - BNR repeat-like domain
NEPIEIGG_02747 9.81e-247 - - - S - - - Tetratricopeptide repeat protein
NEPIEIGG_02748 4.84e-111 maf - - D ko:K06287 - ko00000 COG0424 Nucleotide-binding protein implicated in inhibition of septum formation
NEPIEIGG_02749 0.0 - - - S - - - COG NOG26858 non supervised orthologous group
NEPIEIGG_02750 5.1e-32 alaC - - E - - - Aminotransferase, class I II
NEPIEIGG_02751 4.67e-118 hisI 3.5.4.19, 3.6.1.31 - E ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
NEPIEIGG_02752 3.67e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NEPIEIGG_02753 4.01e-117 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NEPIEIGG_02754 5.3e-302 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NEPIEIGG_02755 4.56e-78 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Psort location CytoplasmicMembrane, score
NEPIEIGG_02756 1.1e-42 - - - EGP - - - Transporter, major facilitator family protein
NEPIEIGG_02757 9e-181 - - - O ko:K05801 - ko00000,ko03110 Psort location Cytoplasmic, score
NEPIEIGG_02759 2.26e-56 - - - CO - - - AhpC TSA family
NEPIEIGG_02760 9.6e-310 - - - M - - - Linear amide C-N hydrolases, choloylglycine hydrolase family
NEPIEIGG_02761 1.85e-61 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NEPIEIGG_02762 3.34e-98 - - - E - - - Psort location Cytoplasmic, score
NEPIEIGG_02763 9.83e-217 - - - M - - - Psort location CytoplasmicMembrane, score
NEPIEIGG_02764 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR Asp-box repeat protein
NEPIEIGG_02765 4.06e-99 - - - S ko:K07011 - ko00000 Glycosyl transferase family group 2
NEPIEIGG_02766 1.19e-211 waaM 2.3.1.241 - M ko:K02517 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Lipid A biosynthesis (KDO)2-(Lauroyl)-lipid IVA acyltransferase
NEPIEIGG_02767 3.48e-95 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 Psort location Cytoplasmic, score 8.96
NEPIEIGG_02770 1.19e-195 - - - C - - - Protein of unknown function (DUF2764)
NEPIEIGG_02772 7.07e-164 - - - S - - - Psort location Cytoplasmic, score 8.96
NEPIEIGG_02773 4.15e-12 - - - - - - - -
NEPIEIGG_02775 5.11e-84 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
NEPIEIGG_02776 5.67e-286 - - - M - - - Glycosyl hydrolases family 43
NEPIEIGG_02777 0.0 - - - M ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
NEPIEIGG_02778 1.42e-212 yfbT - - S - - - HAD hydrolase, family IA, variant 3
NEPIEIGG_02779 7.27e-200 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NEPIEIGG_02780 5.08e-131 - - - V ko:K02004 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
NEPIEIGG_02781 1.37e-287 - - - M ko:K02005 - ko00000 Efflux transporter, RND family, MFP subunit
NEPIEIGG_02782 3.5e-23 - - - - - - - -
NEPIEIGG_02783 1.16e-62 - - - S - - - Transposon-encoded protein TnpV
NEPIEIGG_02784 2.78e-202 asnA 6.3.1.1 - E ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 10.00
NEPIEIGG_02785 9.51e-168 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NEPIEIGG_02786 7.07e-40 - - - M - - - COG COG1082 Sugar phosphate isomerases epimerases
NEPIEIGG_02787 1.53e-158 rnhA 3.1.26.4 - C ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 double-stranded RNA RNA-DNA hybrid binding protein
NEPIEIGG_02788 1.86e-146 - - - S ko:K07078 - ko00000 oxidoreductase related to nitroreductase
NEPIEIGG_02789 1.16e-209 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Psort location Cytoplasmic, score
NEPIEIGG_02793 4.43e-135 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NEPIEIGG_02794 2.13e-68 - - - S - - - COG NOG30624 non supervised orthologous group
NEPIEIGG_02795 5.93e-80 yocK - - T - - - RNA polymerase-binding protein DksA
NEPIEIGG_02796 5.74e-155 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NEPIEIGG_02797 2.04e-38 - - - K - - - Domain of unknown function DUF11
NEPIEIGG_02798 8.69e-31 - - - S - - - Glucosyl transferase GtrII
NEPIEIGG_02800 2.59e-151 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NEPIEIGG_02801 1.23e-180 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NEPIEIGG_02802 1.99e-172 - - - F - - - Domain of unknown function (DUF4922)
NEPIEIGG_02803 1.47e-154 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
NEPIEIGG_02804 1.33e-100 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
NEPIEIGG_02805 2.03e-72 - - - S - - - Pfam:DUF1498
NEPIEIGG_02813 5.34e-128 - - - K - - - Psort location Cytoplasmic, score
NEPIEIGG_02814 2.37e-08 - - - - - - - -
NEPIEIGG_02815 8.79e-178 cvrA - - P ko:K11105 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02816 7.37e-37 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NEPIEIGG_02817 2.45e-302 dxs2 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NEPIEIGG_02821 2.6e-84 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NEPIEIGG_02822 1.37e-104 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NEPIEIGG_02824 9.81e-240 ccs1 - - O - - - Psort location CytoplasmicMembrane, score 10.00
NEPIEIGG_02827 4.34e-46 - - - S - - - PFAM Uncharacterised protein family UPF0150
NEPIEIGG_02828 2.26e-31 - - - N - - - HicA toxin of bacterial toxin-antitoxin,
NEPIEIGG_02833 8.34e-229 - - - M - - - Peptidase, M23

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)