ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HKOPHDEH_00001 0.0 - - - E ko:K21572 - ko00000,ko02000 COG NOG25454 non supervised orthologous group
HKOPHDEH_00002 9.5e-194 - - - S ko:K06921 - ko00000 ATPase (AAA superfamily)
HKOPHDEH_00004 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00005 0.0 - - - K ko:K21572 - ko00000,ko02000 Pfam:SusD
HKOPHDEH_00006 3.39e-148 - - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
HKOPHDEH_00007 1.9e-164 yjjG - - S ko:K07025 - ko00000 HAD hydrolase, TIGR02254 family
HKOPHDEH_00008 5.34e-155 - - - S - - - Transposase
HKOPHDEH_00009 9.06e-159 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKOPHDEH_00010 6.6e-105 - - - S - - - COG NOG23390 non supervised orthologous group
HKOPHDEH_00011 8.47e-139 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HKOPHDEH_00012 1.27e-250 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00014 3.33e-239 - - - V - - - COG0534 Na -driven multidrug efflux pump
HKOPHDEH_00015 1.09e-42 - - - S - - - Winged helix-turn-helix domain (DUF2582)
HKOPHDEH_00016 4.54e-95 - - - J - - - Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HKOPHDEH_00017 2.08e-116 - - - K - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00018 1.62e-65 - - - K - - - stress protein (general stress protein 26)
HKOPHDEH_00019 3.96e-120 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_00020 1.86e-48 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00021 6.17e-165 mscS - - M ko:K03442 - ko00000,ko02000 Small-conductance mechanosensitive channel
HKOPHDEH_00022 0.0 - - - P ko:K02014 - ko00000,ko02000 COG COG1629 Outer membrane receptor proteins, mostly Fe transport
HKOPHDEH_00023 2.68e-136 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HKOPHDEH_00024 7.47e-163 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiamine diphosphokinase
HKOPHDEH_00025 9.82e-220 - - - EG - - - COG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKOPHDEH_00026 2.14e-29 - - - - - - - -
HKOPHDEH_00027 8.44e-71 - - - S - - - Plasmid stabilization system
HKOPHDEH_00028 1.44e-315 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HKOPHDEH_00029 2.85e-307 - 5.4.2.12 - G ko:K15635 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 homoserine kinase
HKOPHDEH_00030 0.0 thrA 1.1.1.3, 2.7.2.4 - E ko:K12524 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HKOPHDEH_00031 1.23e-253 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
HKOPHDEH_00032 2.12e-120 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor
HKOPHDEH_00033 4.83e-278 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HKOPHDEH_00035 2.99e-316 - - - O - - - protein conserved in bacteria
HKOPHDEH_00036 0.0 - - - S - - - COG NOG19133 non supervised orthologous group
HKOPHDEH_00037 2.34e-41 - - - E - - - Glycosyl Hydrolase Family 88
HKOPHDEH_00038 1e-239 - - - E - - - Glycosyl Hydrolase Family 88
HKOPHDEH_00039 0.0 - - - G - - - hydrolase, family 43
HKOPHDEH_00040 0.0 - - - G - - - COG NOG26813 non supervised orthologous group
HKOPHDEH_00041 5.84e-202 - - - G - - - Carbohydrate binding domain protein
HKOPHDEH_00042 0.0 - - - G - - - Carbohydrate binding domain protein
HKOPHDEH_00043 0.0 - - - S ko:K09955 - ko00000 protein conserved in bacteria
HKOPHDEH_00044 0.0 - 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Carbohydrate binding domain protein
HKOPHDEH_00045 0.0 lacZ 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 COG3250 Beta-galactosidase beta-glucuronidase
HKOPHDEH_00046 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_00049 0.0 - - - S - - - Tetratricopeptide repeat
HKOPHDEH_00050 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
HKOPHDEH_00051 1.42e-137 rbr - - C - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00052 0.0 sulP - - P ko:K03321 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00053 5.55e-210 nucA_1 - - F ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 Psort location Extracellular, score
HKOPHDEH_00054 3.5e-124 - - - S - - - COG COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HKOPHDEH_00055 6.15e-187 - - - C - - - radical SAM domain protein
HKOPHDEH_00056 2.72e-260 - - - L - - - Psort location OuterMembrane, score
HKOPHDEH_00057 1.52e-190 - - - L - - - Psort location OuterMembrane, score
HKOPHDEH_00058 1.91e-144 - - - S - - - COG NOG14459 non supervised orthologous group
HKOPHDEH_00059 4.9e-192 - - - S - - - COG4422 Bacteriophage protein gp37
HKOPHDEH_00060 3.25e-225 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00061 4.87e-123 spoU - - J - - - RNA methylase, SpoU family K00599
HKOPHDEH_00062 1.23e-225 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HKOPHDEH_00063 8.24e-137 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKOPHDEH_00064 7.91e-216 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_00065 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HKOPHDEH_00066 5.33e-216 eamA - - EG - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00068 1.4e-158 - - - L - - - COG COG3385 FOG Transposase and inactivated derivatives
HKOPHDEH_00069 5.57e-275 - - - - - - - -
HKOPHDEH_00070 1.39e-233 - - - K ko:K02529 - ko00000,ko03000 Psort location Cytoplasmic, score 9.26
HKOPHDEH_00071 8.08e-108 - - - S - - - COG2373 Large extracellular alpha-helical protein
HKOPHDEH_00072 0.0 - - - S - - - COG2373 Large extracellular alpha-helical protein
HKOPHDEH_00073 1.28e-252 - - - S - - - COG NOG19146 non supervised orthologous group
HKOPHDEH_00074 2.08e-263 argK - - E ko:K07588 - ko00000,ko01000 Lao Ao transport system ATPase
HKOPHDEH_00075 8.5e-129 - - - T - - - Cyclic nucleotide-binding domain
HKOPHDEH_00076 1.4e-206 - - - EG - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00077 2.16e-201 - - - P - - - ATP-binding protein involved in virulence
HKOPHDEH_00078 2.65e-225 - - - P - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00079 4.34e-299 ybdG_2 - - M ko:K16053 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
HKOPHDEH_00080 3.4e-93 - - - L - - - regulation of translation
HKOPHDEH_00081 1.34e-279 - - - N - - - COG NOG06100 non supervised orthologous group
HKOPHDEH_00082 0.0 - - - M - - - TonB-dependent receptor
HKOPHDEH_00083 0.0 - - - T - - - PAS domain S-box protein
HKOPHDEH_00084 0.0 nuoN 1.6.5.3 - C ko:K00343 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKOPHDEH_00085 0.0 nuoM 1.6.5.3 - C ko:K00342 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 proton-translocating NADH-quinone oxidoreductase, chain M
HKOPHDEH_00086 0.0 nuoL 1.6.5.3 - CP ko:K00341 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit
HKOPHDEH_00087 1.01e-62 nuoK 1.6.5.3 - C ko:K00340 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKOPHDEH_00088 3.57e-109 nuoJ 1.6.5.3 - C ko:K00339 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG0839 NADH ubiquinone oxidoreductase subunit 6 (chain J)
HKOPHDEH_00089 1.46e-197 - - - S - - - GDSL-like Lipase/Acylhydrolase
HKOPHDEH_00090 0.0 - 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HKOPHDEH_00091 2.87e-87 - - - T ko:K02481 - ko00000,ko02022 acetoacetate metabolism regulatory protein AtoC
HKOPHDEH_00092 9.54e-202 - - - T ko:K02481 - ko00000,ko02022 acetoacetate metabolism regulatory protein AtoC
HKOPHDEH_00093 0.0 kdpA 3.6.3.12 - P ko:K01546 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HKOPHDEH_00094 0.0 kdpB 3.6.3.12 - P ko:K01547 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HKOPHDEH_00095 2.77e-134 kdpC 3.6.3.12 - P ko:K01548 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HKOPHDEH_00096 1.44e-178 - - - S - - - COG NOG26951 non supervised orthologous group
HKOPHDEH_00097 1.31e-225 kdpD 2.7.13.3 - T ko:K07646 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00098 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_00099 1.52e-207 - - - K - - - methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family)
HKOPHDEH_00100 0.0 - - - EGP - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00101 2.36e-247 - - - V ko:K03543 - ko00000,ko00002,ko02000 Auxiliary transport protein, membrane fusion protein
HKOPHDEH_00102 5.62e-316 - - - MU - - - Psort location OuterMembrane, score
HKOPHDEH_00104 8.36e-90 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00105 0.0 - - - S ko:K07091 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Permease, YjgP YjgQ family
HKOPHDEH_00106 3.66e-294 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HKOPHDEH_00107 1.79e-286 aspC 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 COG0436 Aspartate tyrosine aromatic aminotransferase
HKOPHDEH_00108 1.02e-19 - - - C - - - 4Fe-4S binding domain
HKOPHDEH_00109 1.19e-177 - - - T - - - COG0642 Signal transduction histidine kinase
HKOPHDEH_00110 4.64e-155 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 uracil phosphoribosyltransferase
HKOPHDEH_00111 7.19e-196 - - - - - - - -
HKOPHDEH_00112 0.0 - - - M - - - MBOAT, membrane-bound O-acyltransferase family
HKOPHDEH_00113 6.73e-51 - - - IQ ko:K02078 - ko00000,ko00001 Phosphopantetheine attachment site
HKOPHDEH_00114 0.0 - - - Q - - - AMP-binding enzyme
HKOPHDEH_00115 2.03e-251 oorB 1.2.7.11, 1.2.7.3 - C ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
HKOPHDEH_00116 0.0 porA 1.2.7.11, 1.2.7.3 - C ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 2-oxoacid acceptor oxidoreductase, alpha subunit
HKOPHDEH_00118 8.76e-241 - 4.2.2.7 PL13 M ko:K19050 - ko00000,ko01000 Heparin lyase
HKOPHDEH_00119 2.28e-69 - - - G - - - alpha-L-fucosidase
HKOPHDEH_00120 0.0 - - - CP - - - COG3119 Arylsulfatase A
HKOPHDEH_00121 0.0 - - - - - - - -
HKOPHDEH_00122 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_00123 3.2e-213 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
HKOPHDEH_00124 1.72e-54 - - - S - - - COG NOG18433 non supervised orthologous group
HKOPHDEH_00125 3.33e-60 - - - - - - - -
HKOPHDEH_00126 1.29e-76 - - - S - - - Lipocalin-like
HKOPHDEH_00127 4.8e-175 - - - - - - - -
HKOPHDEH_00128 0.0 hutU 4.2.1.49 - H ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HKOPHDEH_00129 1.07e-210 ftcD 2.1.2.5, 4.3.1.4 - E ko:K00603,ko:K13990 ko00340,ko00670,ko01100,map00340,map00670,map01100 ko00000,ko00001,ko01000,ko03036,ko04147 Glutamate formiminotransferase
HKOPHDEH_00130 4.37e-304 hutI 3.5.2.7 - F ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
HKOPHDEH_00131 7.11e-135 fchA - - E - - - COG3404 Methenyl tetrahydrofolate cyclohydrolase
HKOPHDEH_00132 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
HKOPHDEH_00133 4.32e-155 - - - K - - - transcriptional regulator, TetR family
HKOPHDEH_00134 4.85e-312 - - - MU - - - Psort location OuterMembrane, score
HKOPHDEH_00135 1.68e-236 - - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKOPHDEH_00136 0.0 czcA - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKOPHDEH_00137 3.76e-67 - - - E - - - COG NOG19114 non supervised orthologous group
HKOPHDEH_00138 0.0 - - - E - - - COG COG2755 Lysophospholipase L1 and related esterases
HKOPHDEH_00139 7.54e-151 - - - E - - - COG NOG14456 non supervised orthologous group
HKOPHDEH_00140 5.7e-33 - - - E - - - COG NOG14456 non supervised orthologous group
HKOPHDEH_00141 0.0 algI - - M - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00142 1.02e-192 nagZ2 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain protein
HKOPHDEH_00144 0.0 recD2_2 3.1.11.5 - L ko:K01144 - ko00000,ko01000 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
HKOPHDEH_00145 5.33e-159 - - - - - - - -
HKOPHDEH_00146 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKOPHDEH_00147 1.91e-234 - - - M - - - Peptidase, M23
HKOPHDEH_00148 2.39e-85 ycgE - - K - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00149 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKOPHDEH_00150 0.0 mltD - - M ko:K08307 - ko00000,ko01000,ko01011 Transglycosylase SLT domain
HKOPHDEH_00151 5.9e-186 - - - - - - - -
HKOPHDEH_00152 1.51e-201 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HKOPHDEH_00153 2.57e-174 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain
HKOPHDEH_00154 1.31e-75 - - - S ko:K09793 - ko00000 Psort location CytoplasmicMembrane, score
HKOPHDEH_00155 0.0 - - - E - - - Domain of Unknown Function (DUF1080)
HKOPHDEH_00156 9.13e-192 surE 3.1.3.5 - S ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HKOPHDEH_00157 8.29e-273 lpxB 2.4.1.182 GT19 M ko:K00748 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HKOPHDEH_00158 6.57e-184 - - - S - - - COG NOG29298 non supervised orthologous group
HKOPHDEH_00159 4.01e-199 cdsA 2.7.7.41 - M ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HKOPHDEH_00160 1.74e-35 - - - - - - - -
HKOPHDEH_00161 9.85e-106 - - - S - - - Zeta toxin
HKOPHDEH_00162 7.86e-74 - - - S - - - ATPase (AAA superfamily)
HKOPHDEH_00163 3.29e-313 - - - J ko:K21572 - ko00000,ko02000 Pfam:SusD
HKOPHDEH_00164 1.28e-30 - - - J ko:K21572 - ko00000,ko02000 Pfam:SusD
HKOPHDEH_00165 0.0 - - - H - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00166 4.28e-294 - - - S ko:K07133 - ko00000 ATPase (AAA superfamily)
HKOPHDEH_00167 3.07e-312 - - - J ko:K21572 - ko00000,ko02000 COG NOG25454 non supervised orthologous group
HKOPHDEH_00168 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00170 1.52e-282 - - - L - - - Belongs to the 'phage' integrase family
HKOPHDEH_00171 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00172 7.64e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKOPHDEH_00173 4.94e-186 - - - S ko:K03453 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00174 1.58e-196 - - - C - - - 4Fe-4S binding domain protein
HKOPHDEH_00175 4.82e-55 - - - - - - - -
HKOPHDEH_00176 0.0 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Psort location Cytoplasmic, score
HKOPHDEH_00177 4.61e-287 - - - E - - - Transglutaminase-like superfamily
HKOPHDEH_00178 1.05e-156 - - - S ko:K06973 - ko00000 neutral zinc metallopeptidase
HKOPHDEH_00179 0.0 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
HKOPHDEH_00180 4.79e-311 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKOPHDEH_00181 2.93e-113 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HKOPHDEH_00182 5.24e-158 - - - L - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00183 1.57e-159 - 3.4.14.4 - S ko:K01277 - ko00000,ko01000,ko01002 Peptidase family M49
HKOPHDEH_00184 0.0 - 3.4.14.4 - S ko:K01277 - ko00000,ko01000,ko01002 Peptidase family M49
HKOPHDEH_00185 3.54e-105 - - - K - - - transcriptional regulator (AraC
HKOPHDEH_00186 0.0 recQ3 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HKOPHDEH_00187 3.52e-144 - - - S - - - COG COG0457 FOG TPR repeat
HKOPHDEH_00188 6.83e-236 cysK 2.5.1.47 - E ko:K01738,ko:K12339 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HKOPHDEH_00189 2.71e-261 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HKOPHDEH_00190 9.7e-56 - - - - - - - -
HKOPHDEH_00191 2.58e-103 leuA_1 2.3.1.182 - E ko:K09011 ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the alpha-IPM synthase homocitrate synthase family
HKOPHDEH_00193 2.11e-291 nagC 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_00195 8.84e-274 - - - S - - - Domain of unknown function (DUF5109)
HKOPHDEH_00196 0.0 - - - S - - - C terminal of Calcineurin-like phosphoesterase
HKOPHDEH_00197 0.0 araE - - P ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKOPHDEH_00198 5.06e-312 ce 5.1.3.8 - G ko:K01787 ko00520,map00520 ko00000,ko00001,ko01000 COG COG2942 N-acyl-D-glucosamine 2-epimerase
HKOPHDEH_00199 6.7e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKOPHDEH_00200 2.97e-270 - - - S - - - Domain of unknown function (DUF4434)
HKOPHDEH_00201 0.0 - 3.1.1.53 - G ko:K05970 - ko00000,ko01000 COG NOG04984 non supervised orthologous group
HKOPHDEH_00202 0.0 - - - S - - - Ser Thr phosphatase family protein
HKOPHDEH_00203 0.0 - - - O - - - COG NOG08360 non supervised orthologous group
HKOPHDEH_00204 4.66e-233 glcU - - G ko:K05340 - ko00000,ko02000 COG NOG04879 non supervised orthologous group
HKOPHDEH_00205 0.0 - - - S - - - Domain of unknown function (DUF4434)
HKOPHDEH_00206 1.82e-154 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00208 5.05e-279 ydiI 3.1.2.28 - Q ko:K19222 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00209 0.0 - - - H - - - COG4206 Outer membrane cobalamin receptor protein
HKOPHDEH_00210 1.32e-35 - - - H - - - COG4206 Outer membrane cobalamin receptor protein
HKOPHDEH_00211 2.21e-204 - - - S - - - amine dehydrogenase activity
HKOPHDEH_00212 1.02e-255 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HKOPHDEH_00213 4.11e-230 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKOPHDEH_00214 3.81e-08 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00215 1.59e-303 - - - S - - - CarboxypepD_reg-like domain
HKOPHDEH_00216 1.61e-125 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor
HKOPHDEH_00217 1.15e-201 - - - PT - - - Sigma factor regulatory protein, FecR PupR family
HKOPHDEH_00218 0.0 - - - S - - - CarboxypepD_reg-like domain
HKOPHDEH_00219 1.37e-36 - - - S - - - COG NOG17973 non supervised orthologous group
HKOPHDEH_00220 0.0 - - - P ko:K03281 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00221 0.0 trpB 4.2.1.20 - E ko:K06001 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKOPHDEH_00224 6.09e-276 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 COG2812 DNA polymerase III gamma tau subunits
HKOPHDEH_00225 1.79e-233 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_00226 0.0 - - - S - - - Fibrobacter succinogenes major domain (Fib_succ_major)
HKOPHDEH_00227 1.5e-227 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HKOPHDEH_00228 0.0 prtQ - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00229 4.82e-254 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_00230 5.64e-59 - - - - - - - -
HKOPHDEH_00231 3.8e-77 - - - S ko:K18828 - ko00000,ko01000,ko02048,ko03016 PIN domain
HKOPHDEH_00232 0.0 - - - M ko:K02014 - ko00000,ko02000 Psort location OuterMembrane, score 10.00
HKOPHDEH_00233 8.45e-140 - - - K - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKOPHDEH_00234 0.0 - - - T - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_00235 1.02e-178 - - - S ko:K07137 - ko00000 FAD-dependent
HKOPHDEH_00237 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_00238 0.0 udk2 2.7.1.48 - FJ ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Phosphoribulokinase Uridine kinase family
HKOPHDEH_00239 0.0 - - - P ko:K03324 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00240 3.81e-36 rubR - - C - - - Psort location Cytoplasmic, score
HKOPHDEH_00241 6.39e-280 - - - T - - - COG0642 Signal transduction histidine kinase
HKOPHDEH_00242 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00243 5.31e-149 yihX 3.1.3.10 - S ko:K07025,ko:K20866 ko00010,ko01120,map00010,map01120 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00244 1.33e-225 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin biosynthesis protein
HKOPHDEH_00245 5.61e-113 - - - S - - - Family of unknown function (DUF3836)
HKOPHDEH_00246 2.39e-183 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family
HKOPHDEH_00247 2.11e-147 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_00248 3.45e-138 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_00249 3.41e-144 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_00250 8.83e-39 - - - K ko:K07727 - ko00000,ko03000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00251 4.14e-94 sufE - - S ko:K02426 - ko00000 COG2166 SufE protein probably involved in Fe-S center assembly
HKOPHDEH_00252 1.31e-244 ywaD - - S - - - glutaminyl-peptide cyclotransferase (glutaminyl cyclase) K00683
HKOPHDEH_00253 1.76e-128 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
HKOPHDEH_00254 1.44e-106 - - - S - - - Tetratricopeptide repeat
HKOPHDEH_00255 1.23e-63 - - - S - - - Domain of unknown function (DUF3244)
HKOPHDEH_00256 1.68e-39 - - - O - - - MAC/Perforin domain
HKOPHDEH_00257 3.32e-84 - - - - - - - -
HKOPHDEH_00258 1.05e-161 - - - M - - - Psort location Cytoplasmic, score
HKOPHDEH_00259 3.84e-61 - - - S - - - Glycosyltransferase like family 2
HKOPHDEH_00260 3.69e-103 - - - M - - - Glycosyltransferase like family 2
HKOPHDEH_00261 1.71e-123 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00262 3.25e-84 - - - M - - - Glycosyl transferase family 2
HKOPHDEH_00263 6.43e-225 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKOPHDEH_00264 0.0 - 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Psort location CytoplasmicMembrane, score
HKOPHDEH_00265 1.76e-182 - - - T - - - Lipopolysaccharide kinase (Kdo/WaaP) family
HKOPHDEH_00266 2.01e-133 gmhA 5.3.1.28 - G ko:K03271 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate
HKOPHDEH_00267 1.88e-116 gmhB 3.1.3.82, 3.1.3.83 - E ko:K03273 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Polynucleotide kinase 3 phosphatase
HKOPHDEH_00268 0.0 rfaE 2.7.1.167, 2.7.7.70 - H ko:K03272 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HKOPHDEH_00269 1.26e-244 - - GT9 M ko:K02843 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyltransferase family 9
HKOPHDEH_00270 2.86e-213 - 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 COG COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase
HKOPHDEH_00271 1.63e-127 - - - M - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00272 6.55e-36 - - - - - - - -
HKOPHDEH_00273 8.27e-63 - - - S - - - Domain of unknown function (DUF3244)
HKOPHDEH_00274 6.46e-285 - - - S - - - Tetratricopeptide repeat
HKOPHDEH_00275 1.5e-176 - - - T - - - Carbohydrate-binding family 9
HKOPHDEH_00276 2.08e-264 mdsC - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00277 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_00278 0.0 - - - P - - - COG COG3119 Arylsulfatase A and related enzymes
HKOPHDEH_00279 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00280 0.0 - - - GM ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_00281 0.0 - 4.2.2.5 PL8 N ko:K19049 - ko00000,ko01000 Polysaccharide lyase family 8, super-sandwich domain protein
HKOPHDEH_00285 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKOPHDEH_00286 2.52e-204 - - - S - - - Putative beta-lactamase-inhibitor-like, PepSY-like
HKOPHDEH_00287 2.19e-105 - - - S - - - COG NOG19145 non supervised orthologous group
HKOPHDEH_00288 2.13e-221 - - - - - - - -
HKOPHDEH_00289 2.05e-178 - - - K - - - LytTr DNA-binding domain protein
HKOPHDEH_00290 8.72e-235 - - - T - - - Histidine kinase
HKOPHDEH_00291 1.53e-220 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00292 1.56e-229 - - - C ko:K09181 - ko00000 CoA binding domain protein
HKOPHDEH_00293 1.07e-210 - - - C ko:K09181 - ko00000 CoA binding domain protein
HKOPHDEH_00294 0.0 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI
HKOPHDEH_00295 1.25e-243 - - - CO - - - AhpC TSA family
HKOPHDEH_00296 0.0 - - - S - - - Tetratricopeptide repeat protein
HKOPHDEH_00297 3.82e-227 xerC - - D ko:K04763 - ko00000,ko03036 Tyrosine recombinase XerC
HKOPHDEH_00298 6.15e-95 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
HKOPHDEH_00300 5.3e-201 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Starch synthase, catalytic domain
HKOPHDEH_00301 0.0 - - - S - - - Domain of unknown function (DUF4270)
HKOPHDEH_00302 0.0 amyA 3.2.1.1 GH57 G ko:K07405 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 57 family
HKOPHDEH_00303 0.0 gmhA 2.4.1.346 GT4 M ko:K13668 - ko00000,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HKOPHDEH_00304 0.0 - - - G - - - glycogen debranching enzyme, archaeal type
HKOPHDEH_00306 3.31e-143 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_00307 1.13e-147 - - - K - - - - catabolite gene activator and regulatory subunit of cAMP-dependent protein
HKOPHDEH_00308 2.31e-163 - - - E - - - COG2755 Lysophospholipase L1 and related
HKOPHDEH_00309 3.82e-316 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Psort location Cytoplasmic, score
HKOPHDEH_00310 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HKOPHDEH_00312 2.51e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKOPHDEH_00313 2.02e-219 gap 1.2.1.12 - C ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKOPHDEH_00314 0.0 dcp 3.4.15.5, 3.4.24.70 - E ko:K01284,ko:K01414 - ko00000,ko01000,ko01002 Psort location Cytoplasmic, score
HKOPHDEH_00315 1.99e-111 - - - S - - - COG NOG30732 non supervised orthologous group
HKOPHDEH_00316 0.0 - - - G - - - Glycosyl hydrolase family 9
HKOPHDEH_00317 0.0 - 3.1.1.53 - G ko:K05970 - ko00000,ko01000 COG NOG04984 non supervised orthologous group
HKOPHDEH_00318 1.27e-252 - - - S - - - ATPase (AAA superfamily)
HKOPHDEH_00319 9.92e-104 - - - - - - - -
HKOPHDEH_00320 2.09e-222 - - - N - - - Putative binding domain, N-terminal
HKOPHDEH_00321 2.52e-216 - - - S ko:K07133 - ko00000 AAA domain
HKOPHDEH_00322 0.0 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00323 1.35e-166 pgdA_1 - - G - - - Psort location Cytoplasmic, score
HKOPHDEH_00324 1.22e-218 - - - S - - - Domain of unknown function (DUF4595) with porin-like fold
HKOPHDEH_00326 4.18e-08 - - - S - - - Protein of unknown function (DUF1016)
HKOPHDEH_00327 0.0 - - - G - - - Belongs to the glycosyl hydrolase 2 family
HKOPHDEH_00328 1.36e-244 - - - G - - - Belongs to the glycosyl hydrolase 2 family
HKOPHDEH_00329 0.0 - - - S - - - P-loop ATPase and inactivated derivatives
HKOPHDEH_00330 2.14e-123 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00331 7.51e-145 rnd - - L - - - 3'-5' exonuclease
HKOPHDEH_00332 7.34e-293 rlmI 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 SAM-dependent
HKOPHDEH_00333 1.79e-114 - - - K - - - transcriptional regulator, LuxR family
HKOPHDEH_00334 5.89e-10 maa 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_00335 5.47e-140 - - - S ko:K09702 - ko00000 Protein of unknown function (DUF1349)
HKOPHDEH_00336 6.77e-20 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00337 6.17e-300 nupG - - G ko:K03289,ko:K11537 - ko00000,ko02000 transport of nucleosides, permease protein K03289
HKOPHDEH_00338 4.04e-129 - - - S ko:K08999 - ko00000 Conserved protein
HKOPHDEH_00339 5.9e-168 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKOPHDEH_00340 0.0 - - - S - - - COG NOG26882 non supervised orthologous group
HKOPHDEH_00341 2.15e-152 - - - V ko:K02003 - ko00000,ko00002,ko02000 COG1136 ABC-type antimicrobial peptide transport system ATPase component
HKOPHDEH_00342 8.02e-276 - - - V - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00343 8.87e-155 - 3.2.1.180 GH88 S ko:K18581 - ko00000,ko01000 Glycosyl Hydrolase Family 88
HKOPHDEH_00344 4.98e-107 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HKOPHDEH_00345 6.66e-144 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_00346 5.77e-289 - - - S ko:K07098 - ko00000 Ser Thr phosphatase family protein
HKOPHDEH_00348 4.98e-170 - - - CO - - - Domain of unknown function (DUF4369)
HKOPHDEH_00349 0.0 atsB - - C ko:K06871 - ko00000 COG0641 Arylsulfatase regulator (Fe-S oxidoreductase)
HKOPHDEH_00350 0.0 dpp11 - - E - - - COG NOG04781 non supervised orthologous group
HKOPHDEH_00351 0.0 - - - S - - - COG NOG06390 non supervised orthologous group
HKOPHDEH_00352 2.34e-66 - - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Psort location Cytoplasmic, score
HKOPHDEH_00353 1.18e-98 - - - O - - - Thioredoxin
HKOPHDEH_00354 1.08e-212 - 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00355 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HKOPHDEH_00356 1.16e-195 - - - S - - - COG NOG25193 non supervised orthologous group
HKOPHDEH_00357 1.23e-82 - - - H - - - Susd and RagB outer membrane lipoprotein
HKOPHDEH_00358 0.0 - - - H - - - Susd and RagB outer membrane lipoprotein
HKOPHDEH_00359 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00360 0.0 - - - GM ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_00361 0.0 - - - G - - - Glycosyl hydrolases family 43
HKOPHDEH_00362 8.53e-247 - - - G - - - Belongs to the glycosyl hydrolase 43 family
HKOPHDEH_00363 3.47e-246 - - - G - - - Belongs to the glycosyl hydrolase 43 family
HKOPHDEH_00364 1.1e-260 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 hydrolase, family 43
HKOPHDEH_00365 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Alpha-L-rhamnosidase N-terminal domain protein
HKOPHDEH_00366 0.0 - - - O - - - COG NOG25094 non supervised orthologous group
HKOPHDEH_00367 3.38e-278 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
HKOPHDEH_00368 2.22e-260 fsr - - G ko:K08223 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00369 9.04e-205 - - - E ko:K08717 - ko00000,ko02000 urea transporter
HKOPHDEH_00371 2.13e-68 - - - S - - - COG NOG30624 non supervised orthologous group
HKOPHDEH_00372 4.43e-135 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HKOPHDEH_00373 0.0 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HKOPHDEH_00374 0.0 modF - - P ko:K05776 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC molybdenum transporter, ATP-binding subunit modF
HKOPHDEH_00376 1.84e-155 tal 2.2.1.2 - F ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HKOPHDEH_00377 4.27e-231 ltaS2 - - M - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_00378 3e-200 ltaS2 - - M - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_00379 1.92e-161 ybjG 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00380 0.0 - - - P - - - CarboxypepD_reg-like domain
HKOPHDEH_00381 3.02e-212 - - - S - - - Protein of unknown function (Porph_ging)
HKOPHDEH_00382 0.0 - 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 histidine kinase DNA gyrase B
HKOPHDEH_00383 3.98e-159 - - - K - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKOPHDEH_00384 1.32e-215 - - - M - - - COG NOG19097 non supervised orthologous group
HKOPHDEH_00385 4.95e-259 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKOPHDEH_00386 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HKOPHDEH_00387 0.0 - - - M ko:K07001 - ko00000 Phospholipase, patatin family
HKOPHDEH_00388 0.0 aslA - - P - - - COG COG3119 Arylsulfatase A and related enzymes
HKOPHDEH_00389 1.05e-295 - - - O - - - Glycosyl Hydrolase Family 88
HKOPHDEH_00390 1.17e-96 paaI - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 phenylacetic acid degradation protein
HKOPHDEH_00391 1.6e-206 - - - S - - - Protein of unknown function (DUF3108)
HKOPHDEH_00392 0.0 - - - S - - - COG NOG07965 non supervised orthologous group
HKOPHDEH_00393 1.99e-248 mtrC - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKOPHDEH_00396 1.38e-123 bglX 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 glycosyl hydrolase, family 3
HKOPHDEH_00397 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00398 0.0 - - - S ko:K21572 - ko00000,ko02000 COG NOG26302 non supervised orthologous group
HKOPHDEH_00399 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 glycosyl hydrolase, family 3
HKOPHDEH_00400 4.06e-190 - - - S - - - Endonuclease Exonuclease phosphatase family
HKOPHDEH_00401 0.0 - - - S - - - protein conserved in bacteria
HKOPHDEH_00402 3.46e-136 - - - - - - - -
HKOPHDEH_00403 9.4e-105 - - - K ko:K03088 - ko00000,ko03021 Sigma-70, region 4
HKOPHDEH_00404 7.54e-205 - - - S - - - alpha/beta hydrolase fold
HKOPHDEH_00405 0.0 - - - S - - - PQQ enzyme repeat
HKOPHDEH_00406 0.0 - - - M - - - TonB-dependent receptor
HKOPHDEH_00407 1.75e-204 - - - S - - - COG NOG28036 non supervised orthologous group
HKOPHDEH_00408 1.25e-67 - - - S - - - Belongs to the UPF0145 family
HKOPHDEH_00409 2.65e-307 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family
HKOPHDEH_00410 0.0 sufD - - O ko:K09015 - ko00000 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component
HKOPHDEH_00411 1.05e-175 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component
HKOPHDEH_00412 0.0 sufB - - O ko:K09014 - ko00000 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component
HKOPHDEH_00413 9.31e-54 cvpA - - S ko:K03558 - ko00000 Psort location CytoplasmicMembrane, score
HKOPHDEH_00414 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKOPHDEH_00415 4.01e-44 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKOPHDEH_00416 3.96e-293 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HKOPHDEH_00417 7.46e-106 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HKOPHDEH_00418 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycoside hydrolase, family 3
HKOPHDEH_00419 9.74e-250 bglB 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
HKOPHDEH_00420 1.19e-59 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HKOPHDEH_00421 2.33e-237 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HKOPHDEH_00422 1.45e-279 - - - I - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00423 5.25e-157 - - - S - - - COG NOG31798 non supervised orthologous group
HKOPHDEH_00424 1.08e-86 glpE - - P - - - Rhodanese-like protein
HKOPHDEH_00425 7.48e-234 argF 2.1.3.11, 2.1.3.9 - E ko:K09065,ko:K13043 ko00220,ko01100,ko01230,map00220,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HKOPHDEH_00426 2.52e-302 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKOPHDEH_00427 2.31e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKOPHDEH_00428 1.38e-45 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00429 3.32e-202 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HKOPHDEH_00430 4.15e-75 - - - M ko:K06142 - ko00000 Membrane
HKOPHDEH_00431 2.05e-104 ompH - - M ko:K06142 - ko00000 membrane
HKOPHDEH_00432 0.0 yaeT - - M ko:K07277 - ko00000,ko02000,ko03029 Outer membrane protein assembly complex, YaeT protein
HKOPHDEH_00433 3.42e-180 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKOPHDEH_00434 0.0 - - - G - - - COG NOG27066 non supervised orthologous group
HKOPHDEH_00435 3.25e-252 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKOPHDEH_00436 6.41e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HKOPHDEH_00437 2.06e-160 - - - F - - - NUDIX domain
HKOPHDEH_00438 0.0 - - - S ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKOPHDEH_00439 1.12e-280 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
HKOPHDEH_00440 3.58e-284 galK 2.7.1.6 - H ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family. GalK subfamily
HKOPHDEH_00441 5.79e-305 gluP - - G ko:K02429 - ko00000,ko02000 Transporter, major facilitator family protein
HKOPHDEH_00442 1.32e-295 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
HKOPHDEH_00443 6.9e-233 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00444 1.47e-41 - - - S - - - COG NOG35393 non supervised orthologous group
HKOPHDEH_00445 2.45e-48 - - - S - - - COG NOG30994 non supervised orthologous group
HKOPHDEH_00446 1.15e-35 - - - S - - - COG NOG35214 non supervised orthologous group
HKOPHDEH_00447 1.4e-281 rhlE 3.6.4.13 - JKL ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Belongs to the DEAD box helicase family
HKOPHDEH_00448 1.36e-89 - - - S - - - Lipocalin-like domain
HKOPHDEH_00449 2.35e-99 - - - D - - - Sporulation and cell division repeat protein
HKOPHDEH_00450 3.54e-190 cysQ 3.1.3.7 - P ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 ko00000,ko00001,ko01000,ko03016 3'(2'),5'-bisphosphate nucleotidase
HKOPHDEH_00451 6.17e-236 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKOPHDEH_00452 5.06e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00453 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00454 4.47e-256 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHH family
HKOPHDEH_00455 3.73e-143 - - - S - - - COG NOG30041 non supervised orthologous group
HKOPHDEH_00456 0.0 glmM 5.4.2.8 - G ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00457 1.67e-307 - - - E ko:K03310 - ko00000 Sodium:alanine symporter family
HKOPHDEH_00458 1.08e-122 idi - - I - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00459 2.33e-304 queA 2.4.99.17 - H ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKOPHDEH_00460 7.11e-255 - - - L - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00461 0.0 - - - KLT - - - Protein tyrosine kinase
HKOPHDEH_00462 2.58e-254 - 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Serine/threonine phosphatases, family 2C, catalytic domain
HKOPHDEH_00463 1.26e-229 - - - T - - - Forkhead associated domain
HKOPHDEH_00464 3.84e-111 - 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKOPHDEH_00465 0.0 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00466 5.33e-210 - - - S - - - Domain of unknown function (DUF4886)
HKOPHDEH_00467 0.0 xly - - M - - - fibronectin type III domain protein
HKOPHDEH_00469 1.08e-67 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00470 2.49e-47 - - - O - - - Belongs to the sulfur carrier protein TusA family
HKOPHDEH_00471 0.0 - - - C - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00472 6.45e-163 - - - - - - - -
HKOPHDEH_00473 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKOPHDEH_00474 1.29e-185 dpm1 2.4.1.83 GT2 S ko:K00721 ko00510,ko01100,map00510,map01100 ko00000,ko00001,ko01000,ko01003 b-glycosyltransferase, glycosyltransferase family 2 protein
HKOPHDEH_00476 6.04e-27 - - - - - - - -
HKOPHDEH_00477 6.94e-201 - - - G - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00478 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00479 0.0 - - - S ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_00480 1.64e-142 - - - - - - - -
HKOPHDEH_00481 2.02e-101 - - - H - - - Nucleotidyltransferase substrate-binding family protein
HKOPHDEH_00482 2.79e-69 - - - S - - - Nucleotidyltransferase domain
HKOPHDEH_00483 1.52e-144 - - - L - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00484 0.0 - - - S - - - P-loop ATPase and inactivated derivatives
HKOPHDEH_00485 1.8e-309 - - - S - - - protein conserved in bacteria
HKOPHDEH_00486 0.0 - 3.1.1.17 - G ko:K01053 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 ko00000,ko00001,ko00002,ko01000,ko04147 SMP-30/Gluconolaconase/LRE-like region
HKOPHDEH_00487 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HKOPHDEH_00488 0.0 - - - S - - - Glycosyl Hydrolase Family 88
HKOPHDEH_00489 0.0 lacZ_2 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HKOPHDEH_00490 1.01e-187 uxuB - - IQ - - - Oxidoreductase, short chain dehydrogenase reductase family protein
HKOPHDEH_00491 1.86e-289 uxuA 4.2.1.8 - H ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
HKOPHDEH_00492 4.35e-144 aqpZ - - G ko:K06188 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HKOPHDEH_00493 0.0 bglB 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
HKOPHDEH_00494 1.27e-224 ispB 2.5.1.90 - H ko:K02523 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HKOPHDEH_00495 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKOPHDEH_00496 1.68e-90 - - - S - - - COG NOG29882 non supervised orthologous group
HKOPHDEH_00497 6.7e-146 - - - S ko:K06950 - ko00000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00498 0.0 - - - M - - - Glycosyl hydrolases family 43
HKOPHDEH_00499 4.02e-261 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKOPHDEH_00500 1.5e-53 - - - S - - - Virulence protein RhuM family
HKOPHDEH_00501 1.46e-198 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKOPHDEH_00502 2.09e-60 - - - S - - - ORF6N domain
HKOPHDEH_00503 3.98e-230 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKOPHDEH_00504 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
HKOPHDEH_00507 2.22e-256 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00508 3.32e-147 - - - S - - - Domain of unknown function (DUF5043)
HKOPHDEH_00509 3.74e-148 - - - S - - - Domain of unknown function (DUF5043)
HKOPHDEH_00510 0.0 - - - - - - - -
HKOPHDEH_00511 7.99e-225 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG COG0524 Sugar kinases, ribokinase family
HKOPHDEH_00512 4.2e-139 kdsD 5.3.1.13 - M ko:K06041 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 sugar phosphate isomerase involved in capsule formation
HKOPHDEH_00513 7.54e-304 - - - S - - - Belongs to the peptidase M16 family
HKOPHDEH_00514 8.2e-145 queH 1.17.99.6 - C ko:K09765 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HKOPHDEH_00515 2.97e-288 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00516 0.0 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00517 0.0 - 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 5 (cellulase A) family
HKOPHDEH_00518 2.78e-304 - - - M - - - Glycosyl hydrolase family 2, sugar binding domain protein
HKOPHDEH_00519 3.99e-183 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 biotin acetyl-CoA-carboxylase ligase
HKOPHDEH_00520 9.39e-80 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00521 5.37e-85 - - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
HKOPHDEH_00522 0.0 - - - M - - - COG0793 Periplasmic protease
HKOPHDEH_00523 7.45e-49 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00524 1.13e-93 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKOPHDEH_00525 1.47e-56 - - - S - - - Domain of unknown function (DUF4834)
HKOPHDEH_00526 7.14e-166 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKOPHDEH_00527 1.1e-161 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HKOPHDEH_00528 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
HKOPHDEH_00529 1.66e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HKOPHDEH_00530 1.55e-72 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00531 3.3e-43 - - - S - - - COG NOG34862 non supervised orthologous group
HKOPHDEH_00532 1.75e-95 yjeE - - S ko:K06925 - ko00000,ko03016 Psort location Cytoplasmic, score
HKOPHDEH_00533 1.32e-183 znuB - - P ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HKOPHDEH_00534 1.85e-99 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00535 6.58e-48 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKOPHDEH_00536 1.58e-146 - - - M - - - COG NOG19089 non supervised orthologous group
HKOPHDEH_00537 0.0 fadD 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
HKOPHDEH_00538 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00539 0.0 - - - S - - - Susd and RagB outer membrane lipoprotein
HKOPHDEH_00541 0.0 - - - M - - - Cellulase N-terminal ig-like domain
HKOPHDEH_00542 2.45e-310 - - - S - - - Domain of unknown function (DUF5009)
HKOPHDEH_00543 0.0 - - - Q - - - depolymerase
HKOPHDEH_00544 8.77e-188 - - - T - - - COG NOG17272 non supervised orthologous group
HKOPHDEH_00545 1.56e-49 celA 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 5 (cellulase A) family
HKOPHDEH_00546 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_00547 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
HKOPHDEH_00548 0.0 bga 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HKOPHDEH_00549 0.0 bglB_3 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
HKOPHDEH_00550 8.79e-178 cvrA - - P ko:K11105 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00551 0.0 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG COG1022 Long-chain acyl-CoA synthetases (AMP-forming)
HKOPHDEH_00552 0.0 susB 3.2.1.20, 3.2.1.3 GH31,GH97 G ko:K01187,ko:K21574 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG NOG06228 non supervised orthologous group
HKOPHDEH_00553 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
HKOPHDEH_00554 0.0 - 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 COG NOG34737 non supervised orthologous group
HKOPHDEH_00555 2.82e-293 - - - S ko:K21571 - ko00000 Outer membrane protein SusF_SusE
HKOPHDEH_00556 2.78e-46 - - - S ko:K21571 - ko00000 Outer membrane protein SusF_SusE
HKOPHDEH_00557 0.0 - - - GM ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_00558 3.37e-231 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00559 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00560 1.53e-228 - - - S ko:K21572 - ko00000,ko02000 COG NOG25802 non supervised orthologous group
HKOPHDEH_00561 3.2e-217 - - - S ko:K21572 - ko00000,ko02000 COG NOG25802 non supervised orthologous group
HKOPHDEH_00562 6.67e-237 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKOPHDEH_00563 0.0 ybaL_1 - - PT - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00564 5.66e-168 hypB - - H ko:K22132 - ko00000,ko03016 involved in molybdopterin and thiamine biosynthesis family 1
HKOPHDEH_00565 1.34e-153 lolD - - V ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner
HKOPHDEH_00566 0.0 - - - P - - - Outer membrane protein beta-barrel family
HKOPHDEH_00567 4.24e-216 comEA - - L - - - COG COG1555 DNA uptake protein and related DNA-binding proteins
HKOPHDEH_00568 0.0 - - - P ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HKOPHDEH_00569 0.0 - - - E - - - Transglutaminase-like protein
HKOPHDEH_00570 3.98e-187 spoU - - H ko:K03437 - ko00000,ko03016 RNA methyltransferase TrmH family
HKOPHDEH_00571 1.19e-254 yjmD_2 - - E ko:K18369 ko00640,map00640 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_00572 2.52e-39 - - - - - - - -
HKOPHDEH_00573 7.1e-46 - - - S - - - Haemolytic
HKOPHDEH_00576 2.86e-139 - - - - - - - -
HKOPHDEH_00577 1.49e-101 - - - S - - - Lipocalin-like domain
HKOPHDEH_00578 1.59e-162 - - - - - - - -
HKOPHDEH_00579 8.15e-94 - - - - - - - -
HKOPHDEH_00580 3.28e-52 - - - - - - - -
HKOPHDEH_00581 6.46e-31 - - - - - - - -
HKOPHDEH_00582 1.04e-136 - - - L - - - Phage integrase family
HKOPHDEH_00583 4.06e-102 - - - L ko:K03630 - ko00000 DNA repair
HKOPHDEH_00584 8.95e-176 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00585 5.73e-23 - - - - - - - -
HKOPHDEH_00586 1.28e-274 yghO - - K - - - COG NOG07967 non supervised orthologous group
HKOPHDEH_00587 1.89e-204 yrbG - - P ko:K07301 - ko00000,ko02000 K -dependent Na Ca exchanger
HKOPHDEH_00588 1.24e-20 mscM - - M - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00589 7.03e-88 mscM - - M - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00590 7.85e-126 mscM - - M - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00591 1.2e-123 - - - S - - - Domain of unknown function (DUF4784)
HKOPHDEH_00592 3.22e-110 - - - S - - - Domain of unknown function (DUF4784)
HKOPHDEH_00593 1.66e-152 - 3.1.3.2 - S ko:K14379 ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323 ko00000,ko00001,ko01000 Purple acid phosphatase
HKOPHDEH_00594 0.0 - - - M - - - Psort location OuterMembrane, score
HKOPHDEH_00595 8.67e-275 - - - L - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00596 9.36e-147 ddpX 3.4.13.22 - M ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HKOPHDEH_00597 2.04e-215 - - - S - - - Peptidase M50
HKOPHDEH_00598 1.38e-53 - - - M - - - Polymer-forming cytoskeletal
HKOPHDEH_00599 5.04e-184 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_00600 2.54e-132 qacR - - K - - - transcriptional regulator, TetR family
HKOPHDEH_00601 5.8e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 with different specificities (related to short-chain alcohol
HKOPHDEH_00602 1.51e-161 rluC 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 ribosomal pseudouridine synthase C, large subunit
HKOPHDEH_00603 0.0 - - - EU - - - Peptidase, S9A B C family, catalytic domain protein
HKOPHDEH_00604 4.59e-06 - - - - - - - -
HKOPHDEH_00605 2.9e-254 - - - S - - - Putative binding domain, N-terminal
HKOPHDEH_00606 0.0 - - - S - - - Domain of unknown function (DUF4302)
HKOPHDEH_00607 5.11e-214 - - - S - - - Putative zinc-binding metallo-peptidase
HKOPHDEH_00608 0.0 - - - E ko:K21572 - ko00000,ko02000 Starch-binding associating with outer membrane
HKOPHDEH_00609 1.04e-269 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00610 0.0 nrd 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HKOPHDEH_00611 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 9.26
HKOPHDEH_00612 4.25e-82 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKOPHDEH_00613 7.83e-123 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
HKOPHDEH_00614 7.32e-247 - - - S ko:K07011 - ko00000 Glycosyl transferase family group 2
HKOPHDEH_00615 1.19e-211 waaM 2.3.1.241 - M ko:K02517 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Lipid A biosynthesis (KDO)2-(Lauroyl)-lipid IVA acyltransferase
HKOPHDEH_00616 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00617 0.0 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 Psort location CytoplasmicMembrane, score 9.82
HKOPHDEH_00618 3.27e-19 - - - S - - - COG NOG38865 non supervised orthologous group
HKOPHDEH_00619 1.03e-50 - - - S - - - RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HKOPHDEH_00621 7.23e-92 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HKOPHDEH_00622 1.54e-56 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKOPHDEH_00625 0.0 - - - J ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_00626 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00627 3.77e-194 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HKOPHDEH_00628 1.36e-243 - 4.6.1.13 - U ko:K01771 ko00562,map00562 ko00000,ko00001,ko01000 Phosphatidylinositol-specific phospholipase C, X domain
HKOPHDEH_00629 9.1e-189 yaaA - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HKOPHDEH_00630 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 single-stranded-DNA-specific exonuclease recJ
HKOPHDEH_00631 2.69e-191 - - - V ko:K01992 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00632 1.24e-258 - - - E - - - COG NOG09493 non supervised orthologous group
HKOPHDEH_00633 0.0 - - - CO - - - COG NOG24773 non supervised orthologous group
HKOPHDEH_00634 0.0 - - - S - - - Oxidoreductase NAD-binding domain protein
HKOPHDEH_00635 7.67e-80 - - - K - - - Transcriptional regulator
HKOPHDEH_00636 0.0 - - - U - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HKOPHDEH_00638 1.58e-250 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HKOPHDEH_00639 5.46e-183 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKOPHDEH_00640 1.62e-255 ilvE 2.6.1.42 - EH ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase
HKOPHDEH_00641 3.92e-37 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKOPHDEH_00642 9.28e-89 - - - S - - - Lipocalin-like domain
HKOPHDEH_00643 9.17e-95 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKOPHDEH_00644 0.0 - - - S - - - protein conserved in bacteria
HKOPHDEH_00645 0.0 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase, middle domain
HKOPHDEH_00646 0.0 - 3.2.1.20 GH31 M ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG NOG06228 non supervised orthologous group
HKOPHDEH_00647 0.0 - - - T - - - Response regulator receiver domain protein
HKOPHDEH_00648 4.15e-166 - - - T - - - Response regulator receiver domain protein
HKOPHDEH_00650 1.28e-82 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKOPHDEH_00652 2.88e-294 purH2 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
HKOPHDEH_00653 0.0 - - - A - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00654 3.61e-289 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
HKOPHDEH_00655 2.41e-192 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKOPHDEH_00656 6.92e-215 - - - S ko:K07027 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00657 0.0 pepD_2 - - E ko:K01270 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Xaa-His dipeptidase
HKOPHDEH_00660 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 COG COG3250 Beta-galactosidase beta-glucuronidase
HKOPHDEH_00661 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 COG COG3250 Beta-galactosidase beta-glucuronidase
HKOPHDEH_00662 0.0 - 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Beta-galactosidase trimerisation domain
HKOPHDEH_00663 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Beta galactosidase small chain
HKOPHDEH_00664 0.0 - 3.2.1.20 GH31 M ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl-hydrolase 97 C-terminal, oligomerisation
HKOPHDEH_00665 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKOPHDEH_00666 1.19e-45 - - - S - - - COG NOG33517 non supervised orthologous group
HKOPHDEH_00667 1.66e-252 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00668 0.0 - 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 polysaccharide deacetylase
HKOPHDEH_00669 3.12e-224 dnaJ2 - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 Psort location Cytoplasmic, score
HKOPHDEH_00670 3.11e-71 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00671 0.0 acd - - C - - - Acyl-CoA dehydrogenase, C-terminal domain
HKOPHDEH_00672 1.63e-158 - - - M ko:K03832 - ko00000,ko02000 MORN repeat variant
HKOPHDEH_00673 4.39e-244 etfA - - C ko:K03522 - ko00000,ko04147 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00674 3.58e-206 etfB - - C ko:K03521 - ko00000 COG2086 Electron transfer flavoprotein beta subunit
HKOPHDEH_00675 0.0 mrdA 3.4.16.4 - M ko:K05515 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein 2
HKOPHDEH_00677 1.47e-54 mreD - - S - - - rod shape-determining protein MreD
HKOPHDEH_00678 5.28e-200 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HKOPHDEH_00679 2.63e-241 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein, MreB Mrl family
HKOPHDEH_00680 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 bifunctional purine biosynthesis protein PurH
HKOPHDEH_00682 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HKOPHDEH_00683 0.0 - - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HKOPHDEH_00684 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_00685 7.12e-184 - - - Q - - - COG3458 Acetyl esterase (deacetylase)
HKOPHDEH_00686 0.0 - 3.2.1.78 - G ko:K19355 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 5 (cellulase A) family
HKOPHDEH_00687 4.71e-243 eglS 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 5 (cellulase A) family
HKOPHDEH_00689 3.69e-54 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00690 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00691 0.0 - - - S ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_00692 0.0 - - - - - - - -
HKOPHDEH_00693 0.0 - - - U - - - domain, Protein
HKOPHDEH_00694 1.98e-314 gldE - - S - - - Gliding motility-associated protein GldE
HKOPHDEH_00695 1.16e-149 sfp - - H - - - Belongs to the P-Pant transferase superfamily
HKOPHDEH_00696 0.0 tnaA 4.1.99.1 - E ko:K01667 ko00380,map00380 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00697 2.23e-104 - 2.7.13.3 - T ko:K02484,ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_00698 1.83e-304 - 2.7.13.3 - T ko:K02484,ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_00699 3.82e-158 srrA - - K ko:K07657,ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKOPHDEH_00700 5.31e-284 - - - T - - - COG NOG06399 non supervised orthologous group
HKOPHDEH_00701 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00702 7.27e-144 - - - S ko:K07043 - ko00000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00703 2.31e-122 - - - S - - - COG NOG16223 non supervised orthologous group
HKOPHDEH_00704 0.0 - - - P - - - Psort location OuterMembrane, score 9.52
HKOPHDEH_00705 5.55e-91 - - - - - - - -
HKOPHDEH_00706 0.0 - - - KT - - - response regulator
HKOPHDEH_00707 1.17e-100 - - - C - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00708 9.48e-109 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HKOPHDEH_00709 1.09e-175 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HKOPHDEH_00710 0.0 speA 4.1.1.19 - H ko:K01585 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the biosynthesis of agmatine from arginine
HKOPHDEH_00711 6.65e-121 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKOPHDEH_00712 1.86e-146 - - - S ko:K07078 - ko00000 oxidoreductase related to nitroreductase
HKOPHDEH_00714 3.42e-196 - - - - - - - -
HKOPHDEH_00715 5.35e-81 - - - K - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00716 1.16e-205 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00717 2.93e-198 cbiO - - V ko:K01990 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
HKOPHDEH_00718 6.06e-224 - - - K ko:K18954 - ko00000,ko03000 methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family) K00567
HKOPHDEH_00719 0.0 - - - S - - - tetratricopeptide repeat
HKOPHDEH_00720 6.55e-223 - - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 COG0226 ABC-type phosphate transport system, periplasmic component
HKOPHDEH_00721 2.47e-184 tonB2 - - U ko:K03832 - ko00000,ko02000 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HKOPHDEH_00722 1.05e-144 exbD2 - - U - - - Biopolymer transport protein ExbD/TolR
HKOPHDEH_00723 5.27e-133 exbD1 - - U - - - Biopolymer transport protein ExbD/TolR
HKOPHDEH_00724 2.56e-181 exbB - - U ko:K03561 - ko00000,ko02000 MotA TolQ ExbB proton channel family
HKOPHDEH_00725 3.09e-97 - - - - - - - -
HKOPHDEH_00726 1.41e-115 - - - M - - - Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKOPHDEH_00727 0.0 czcA - - P - - - Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKOPHDEH_00728 2.91e-277 - - - MU - - - outer membrane efflux protein
HKOPHDEH_00729 5.46e-299 - - - O ko:K13963 ko05146,map05146 ko00000,ko00001 SERine Proteinase INhibitors
HKOPHDEH_00730 0.0 rsmF - - J - - - NOL1 NOP2 sun family
HKOPHDEH_00731 0.0 - - - P ko:K16089 - ko00000,ko02000 COG4771 Outer membrane receptor for ferrienterochelin and colicins
HKOPHDEH_00732 1.87e-16 - - - - - - - -
HKOPHDEH_00734 9.71e-224 - - - K - - - Psort location Cytoplasmic, score
HKOPHDEH_00735 1.04e-270 fucO 1.1.1.77 - C ko:K00048 ko00630,ko00640,ko01120,map00630,map00640,map01120 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_00736 2.72e-196 rhaD 4.1.2.19 - G ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HKOPHDEH_00737 1.36e-241 rhaT - - EG ko:K02856 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00738 1.33e-314 rhaA 5.3.1.14 - G ko:K01813 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00739 0.0 rhaB 2.7.1.5, 2.7.1.51 - G ko:K00848,ko:K00879 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HKOPHDEH_00740 0.0 - - - G - - - Glycosyl hydrolase family 2, sugar binding domain protein
HKOPHDEH_00741 1.31e-223 - - - G - - - Glycosyl hydrolase family 92
HKOPHDEH_00742 7.79e-302 - - - C - - - Oxidoreductase, FAD FMN-binding protein
HKOPHDEH_00743 3.84e-185 - 1.3.1.22 - S ko:K12343 ko00140,map00140 ko00000,ko00001,ko01000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00744 0.0 prpC 2.3.3.1, 2.3.3.5 - C ko:K01647,ko:K01659 ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_00745 5.38e-158 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_00746 1.55e-107 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_00747 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_00748 0.0 - - - L - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00749 1.68e-252 ilvC 1.1.1.86 - E ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ketol-acid reductoisomerase
HKOPHDEH_00750 5.71e-161 - 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HKOPHDEH_00753 2.2e-140 - - - L - - - Transposase, IS605 OrfB family
HKOPHDEH_00754 5.95e-284 yieG - - S ko:K06901 - ko00000,ko02000 Permease
HKOPHDEH_00755 2.62e-245 - - - - - - - -
HKOPHDEH_00756 7.07e-76 - - - S - - - Outer membrane protein beta-barrel domain
HKOPHDEH_00757 0.0 - 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Peptidase family S41
HKOPHDEH_00758 1.05e-180 - - - - - - - -
HKOPHDEH_00759 8.06e-259 - - - - - - - -
HKOPHDEH_00760 2.68e-230 - - - P - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00761 0.0 - - - S - - - Heparinase II/III-like protein
HKOPHDEH_00762 0.0 - - - KT - - - Y_Y_Y domain
HKOPHDEH_00763 3.19e-117 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HKOPHDEH_00764 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00766 1.35e-312 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HKOPHDEH_00767 8.11e-262 - 3.1.3.97 - S ko:K07053 - ko00000,ko01000 Domain of unknown function
HKOPHDEH_00768 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Alpha galactosidase A
HKOPHDEH_00769 1.61e-296 - - - - - - - -
HKOPHDEH_00770 0.0 - - - M ko:K21572 - ko00000,ko02000 Pfam:SusD
HKOPHDEH_00771 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00772 1.51e-262 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HKOPHDEH_00773 1.01e-184 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 COG0226 ABC-type phosphate transport system, periplasmic component
HKOPHDEH_00774 0.0 glnS 6.1.1.18 - J ko:K01886 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glutamine--tRNA ligase
HKOPHDEH_00775 5.43e-245 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00776 4.66e-37 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00777 1.07e-151 dedA - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_00778 2.45e-114 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKOPHDEH_00779 4.71e-135 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00780 1.52e-130 - - - L - - - COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
HKOPHDEH_00781 3.34e-294 pglE - - E - - - Belongs to the DegT DnrJ EryC1 family
HKOPHDEH_00782 5.24e-148 - - - S - - - Metallo-beta-lactamase superfamily
HKOPHDEH_00783 7.29e-222 luxE - - H - - - phenylacetate-CoA ligase activity
HKOPHDEH_00784 3.72e-142 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HKOPHDEH_00785 7.33e-135 - - - T - - - COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HKOPHDEH_00786 3.49e-23 - - - - - - - -
HKOPHDEH_00787 0.0 - - - S - - - Large extracellular alpha-helical protein
HKOPHDEH_00788 2.62e-287 - - - S - - - Domain of unknown function (DUF4249)
HKOPHDEH_00789 9.25e-293 - - - S - - - Domain of unknown function (DUF4249)
HKOPHDEH_00790 0.0 - - - M - - - CarboxypepD_reg-like domain
HKOPHDEH_00791 9.08e-165 - - - P - - - TonB-dependent receptor
HKOPHDEH_00792 1.06e-83 yccF - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_00793 1.58e-263 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKOPHDEH_00794 4.22e-76 - - - S - - - COG NOG29451 non supervised orthologous group
HKOPHDEH_00795 3.38e-64 - - - Q - - - Esterase PHB depolymerase
HKOPHDEH_00796 0.0 - - - T - - - COG0642 Signal transduction histidine kinase
HKOPHDEH_00797 3.02e-296 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00798 4.57e-38 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00800 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKOPHDEH_00801 6.83e-255 - - - - - - - -
HKOPHDEH_00802 5.39e-240 - - - E - - - GSCFA family
HKOPHDEH_00803 0.0 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKOPHDEH_00804 2.2e-25 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HKOPHDEH_00805 1.62e-190 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HKOPHDEH_00810 5.23e-102 - - - - - - - -
HKOPHDEH_00811 5.28e-100 - - - C - - - lyase activity
HKOPHDEH_00812 2.75e-38 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HKOPHDEH_00813 2.68e-56 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HKOPHDEH_00814 3.97e-136 rbr3A - - C - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00815 3.12e-104 fur - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HKOPHDEH_00816 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HKOPHDEH_00817 5.03e-191 - - - ET - - - COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain
HKOPHDEH_00818 0.0 - - - H - - - COG NOG07963 non supervised orthologous group
HKOPHDEH_00819 1.38e-125 porG 1.2.7.3 - C ko:K00177 ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200 br01601,ko00000,ko00001,ko00002,ko01000 2-oxoacid ferredoxin flavodoxin oxidoreductase, gamma subunit
HKOPHDEH_00820 4.51e-187 vorA 1.2.7.11, 1.2.7.3 - C ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
HKOPHDEH_00821 1.91e-31 - - - - - - - -
HKOPHDEH_00822 9.41e-257 vorB 1.2.7.11, 1.2.7.3 - C ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
HKOPHDEH_00824 1.19e-167 - - - K - - - Transcriptional regulator
HKOPHDEH_00825 1.44e-229 - - - C - - - 4Fe-4S dicluster domain
HKOPHDEH_00826 0.0 susB 3.2.1.20, 3.2.1.3 GH31,GH97 G ko:K01187,ko:K21574 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG NOG06228 non supervised orthologous group
HKOPHDEH_00827 2.47e-107 - - - L - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00828 8.46e-84 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKOPHDEH_00829 2.23e-67 - - - S - - - Pentapeptide repeat protein
HKOPHDEH_00830 4.75e-305 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKOPHDEH_00831 6.65e-316 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 glycosyl hydrolase, family 3
HKOPHDEH_00832 0.0 bepE_4 - - V ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKOPHDEH_00833 6.02e-248 - - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKOPHDEH_00834 9.08e-219 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKOPHDEH_00835 4.88e-133 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKOPHDEH_00836 3.67e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HKOPHDEH_00837 1.78e-123 - - - M - - - Nucleoside 2-deoxyribosyltransferase like
HKOPHDEH_00838 1.19e-207 - - - EG - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00839 0.0 actP 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00840 1.01e-62 - - - D - - - Septum formation initiator
HKOPHDEH_00841 2.96e-72 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_00842 0.0 - - - S - - - Domain of unknown function (DUF5121)
HKOPHDEH_00843 0.0 - 3.2.1.45 GH30 G ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 30 family
HKOPHDEH_00844 0.0 - - - GM ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_00845 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00846 0.0 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00849 4.12e-22 - 3.6.4.13, 5.4.99.21 - NU ko:K03578,ko:K06182 - ko00000,ko01000,ko03009 translation initiation factor activity
HKOPHDEH_00851 5.97e-176 - - - O - - - SPFH Band 7 PHB domain protein
HKOPHDEH_00852 8.41e-205 - - - EGP - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00853 8.65e-135 - - - EGP - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00854 4.39e-225 emrA_1 - - V ko:K03543 - ko00000,ko00002,ko02000 Auxiliary transport protein, membrane fusion protein (MFP) family protein
HKOPHDEH_00855 7.83e-291 - - - MU - - - Outer membrane efflux protein
HKOPHDEH_00857 6.12e-76 - - - S - - - Cupin domain
HKOPHDEH_00858 2.5e-296 - - - M - - - tail specific protease
HKOPHDEH_00860 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
HKOPHDEH_00861 0.0 - 3.1.1.53 - G ko:K05970 - ko00000,ko01000 COG NOG04984 non supervised orthologous group
HKOPHDEH_00863 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit
HKOPHDEH_00864 7.14e-195 - - - S - - - COG NOG19130 non supervised orthologous group
HKOPHDEH_00865 2.28e-256 - - - M - - - peptidase S41
HKOPHDEH_00866 6.32e-293 coaBC 4.1.1.36, 6.3.2.5 - H ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKOPHDEH_00867 3.29e-186 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 COG0847 DNA polymerase III epsilon subunit and related 3'-5'
HKOPHDEH_00868 9.43e-259 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKOPHDEH_00869 1.72e-86 - - - L - - - COG NOG19098 non supervised orthologous group
HKOPHDEH_00870 0.0 - - - S - - - COG NOG25407 non supervised orthologous group
HKOPHDEH_00871 2.67e-179 lipB 3.1.4.55 - S ko:K06167 ko00440,map00440 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00872 1.03e-241 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HKOPHDEH_00873 9.56e-208 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00874 1.29e-230 ltd - - M - - - NAD dependent epimerase dehydratase family
HKOPHDEH_00876 4.75e-129 - - - - - - - -
HKOPHDEH_00877 7.82e-97 ybeY - - S - - - Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKOPHDEH_00878 1.84e-281 spmA - - S ko:K06373 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00879 1.05e-253 - - - S - - - Psort location Extracellular, score
HKOPHDEH_00880 7.16e-170 - - - L - - - DNA alkylation repair enzyme
HKOPHDEH_00881 1.81e-103 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00882 1.36e-210 - - - S - - - AAA ATPase domain
HKOPHDEH_00883 8.94e-54 - - - S - - - Domain of unknown function (DUF4276)
HKOPHDEH_00884 1.04e-247 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKOPHDEH_00885 0.0 - - - S ko:K21572 - ko00000,ko02000 Pfam:SusD
HKOPHDEH_00886 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00887 7.29e-283 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00888 1.31e-201 - - - G ko:K05340 - ko00000,ko02000 COG NOG04879 non supervised orthologous group
HKOPHDEH_00889 0.0 - - - G - - - L-fucose isomerase, C-terminal domain
HKOPHDEH_00890 0.0 - - - G - - - FGGY family of carbohydrate kinases, N-terminal domain
HKOPHDEH_00891 4.19e-210 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
HKOPHDEH_00892 3.4e-166 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 XFP N-terminal domain
HKOPHDEH_00893 2.05e-39 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
HKOPHDEH_00894 9.63e-124 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Psort location Cytoplasmic, score 9.97
HKOPHDEH_00896 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_00897 2.16e-246 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HKOPHDEH_00898 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Psort location Cytoplasmic, score
HKOPHDEH_00899 2.74e-118 - - - S - - - COG NOG27649 non supervised orthologous group
HKOPHDEH_00900 4.7e-108 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKOPHDEH_00901 3.54e-82 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HKOPHDEH_00902 1.23e-174 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HKOPHDEH_00903 2.47e-225 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKOPHDEH_00904 8.75e-78 - - - J ko:K03113 ko03013,map03013 ko00000,ko00001,ko03012 COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related
HKOPHDEH_00905 1.88e-36 - - - KT - - - response regulator
HKOPHDEH_00906 0.0 - - - P - - - TonB-dependent receptor
HKOPHDEH_00907 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3 C-terminal domain protein
HKOPHDEH_00908 6.73e-217 - - - O - - - SPFH Band 7 PHB domain protein
HKOPHDEH_00909 0.0 - - - O ko:K06889 - ko00000 COG COG1073 Hydrolases of the alpha beta superfamily
HKOPHDEH_00910 6.1e-40 - - - S - - - COG NOG17292 non supervised orthologous group
HKOPHDEH_00911 1.35e-102 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_00912 0.0 - - - S - - - Psort location OuterMembrane, score
HKOPHDEH_00913 5.6e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKOPHDEH_00914 2.1e-246 - - - M - - - Psort location CytoplasmicMembrane, score 9.46
HKOPHDEH_00915 2.59e-160 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
HKOPHDEH_00916 2.03e-67 yitW - - S - - - FeS assembly SUF system protein
HKOPHDEH_00917 1.3e-191 lpxH 3.6.1.54 - S ko:K03269 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Psort location Cytoplasmic, score
HKOPHDEH_00918 0.0 - - - G - - - YdjC-like protein
HKOPHDEH_00919 1.37e-41 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00920 0.0 - 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HKOPHDEH_00921 6.74e-287 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKOPHDEH_00922 3.55e-234 pta 2.3.1.8 - C ko:K00625,ko:K13788 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_00923 3.65e-90 - - - S - - - COG NOG32529 non supervised orthologous group
HKOPHDEH_00924 0.0 - - - S - - - Phosphoadenosine phosphosulfate reductase family
HKOPHDEH_00925 2.93e-125 ibrB - - K - - - Psort location Cytoplasmic, score
HKOPHDEH_00926 4.49e-232 - 4.1.1.35 - GM ko:K08678 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase dehydratase family
HKOPHDEH_00927 9.13e-262 pleD 2.7.13.3 - T ko:K11527 - ko00000,ko01000,ko01001,ko02022 Response regulator receiver domain protein
HKOPHDEH_00928 0.0 - - - L - - - DNA-dependent ATPase I and helicase II
HKOPHDEH_00929 0.0 addA - - L - - - Belongs to the helicase family. UvrD subfamily
HKOPHDEH_00930 1.67e-198 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00931 0.0 - - - GM - - - SusD family
HKOPHDEH_00932 8.8e-211 - - - - - - - -
HKOPHDEH_00933 2.96e-100 - - - - - - - -
HKOPHDEH_00934 4.1e-156 - - - L - - - Bacterial DNA-binding protein
HKOPHDEH_00935 5.34e-304 - - - S - - - P-loop ATPase and inactivated derivatives
HKOPHDEH_00936 8.92e-273 - - - J - - - endoribonuclease L-PSP
HKOPHDEH_00937 1.58e-140 - - - S - - - Domain of unknown function (DUF4369)
HKOPHDEH_00938 2.31e-249 - - - M - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00939 2.66e-250 - - - M - - - Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKOPHDEH_00940 0.0 - - - V - - - Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKOPHDEH_00941 0.0 - - - MU - - - Psort location OuterMembrane, score
HKOPHDEH_00943 1.28e-311 tig - - O ko:K03545 - ko00000 peptidyl-prolyl cis-trans isomerase (trigger factor)
HKOPHDEH_00944 5.04e-154 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKOPHDEH_00945 1.24e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKOPHDEH_00946 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HKOPHDEH_00947 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HKOPHDEH_00948 0.0 - 5.2.1.8 - M ko:K03771 - ko00000,ko01000,ko03110 COG COG0760 Parvulin-like peptidyl-prolyl isomerase
HKOPHDEH_00949 2.52e-203 - - - O - - - COG NOG23400 non supervised orthologous group
HKOPHDEH_00950 5.92e-193 pfkA 2.7.1.11, 2.7.1.90 - F ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKOPHDEH_00951 5.09e-200 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKOPHDEH_00952 2.96e-304 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKOPHDEH_00953 7.43e-45 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKOPHDEH_00954 3.57e-141 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKOPHDEH_00955 0.0 - - - S ko:K07014 - ko00000 Domain of unknown function (DUF3413)
HKOPHDEH_00956 1.61e-250 pdxB 1.1.1.290 - H ko:K03473 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate
HKOPHDEH_00957 1.95e-45 - - - - - - - -
HKOPHDEH_00958 4.07e-24 - - - - - - - -
HKOPHDEH_00960 3.78e-142 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKOPHDEH_00961 2e-23 - - - M ko:K07271 - ko00000,ko01000 COG COG3475 LPS biosynthesis protein
HKOPHDEH_00962 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_00963 0.0 - - - GM ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_00964 4.28e-309 - - - S - - - Glycosyl Hydrolase Family 88
HKOPHDEH_00965 0.0 hepC 4.2.2.8 PL12 M ko:K19052 - ko00000,ko01000 Heparinase II III-like protein
HKOPHDEH_00969 2.05e-185 kdsA 2.5.1.55 - H ko:K01627 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the KdsA family
HKOPHDEH_00970 1.97e-229 - - - I - - - lipid kinase, YegS Rv2252 BmrU family
HKOPHDEH_00971 1.8e-219 miaA2 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKOPHDEH_00973 1.57e-22 - - - V - - - COG0534 Na -driven multidrug efflux pump
HKOPHDEH_00974 2.04e-220 - - - V - - - COG0534 Na -driven multidrug efflux pump
HKOPHDEH_00975 1.79e-156 - - - S ko:K18234 - ko00000,ko01000,ko01504 Bacterial transferase hexapeptide repeat protein
HKOPHDEH_00976 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 COG COG3973 Superfamily I DNA and RNA helicases
HKOPHDEH_00977 2.1e-140 - - - S - - - COG NOG23385 non supervised orthologous group
HKOPHDEH_00978 2.23e-63 - - - K - - - COG NOG38984 non supervised orthologous group
HKOPHDEH_00979 0.0 - - - P - - - non supervised orthologous group
HKOPHDEH_00980 0.0 - - - J ko:K21572 - ko00000,ko02000 Pfam:SusD
HKOPHDEH_00981 8.87e-291 - - - T - - - COG COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases
HKOPHDEH_00982 4.87e-155 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant
HKOPHDEH_00984 3.72e-202 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HKOPHDEH_00985 1.98e-167 rsmI_1 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00986 1.66e-267 - - - I - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_00987 7.61e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HKOPHDEH_00988 4.22e-210 rhaR_1 - - K - - - transcriptional regulator (AraC family)
HKOPHDEH_00989 0.0 mutB 5.4.99.2 - I ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00990 0.0 mutA 5.4.99.2 - I ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 methylmalonyl-CoA mutase small subunit
HKOPHDEH_00991 0.0 - - - P ko:K07085 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00992 6.56e-227 - - - M - - - Right handed beta helix region
HKOPHDEH_00993 1.46e-148 - - - F - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_00994 6.2e-189 - - - V - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_00996 1.8e-273 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HKOPHDEH_00997 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00998 5.74e-20 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Psort location Cytoplasmic, score 8.96
HKOPHDEH_00999 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKOPHDEH_01000 3.48e-87 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Class II glutamine amidotransferase
HKOPHDEH_01001 0.0 - - - M - - - Tricorn protease homolog
HKOPHDEH_01002 0.0 - - - G - - - unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HKOPHDEH_01003 0.0 - - - K ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_01004 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01005 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01006 0.0 - - - S ko:K21572 - ko00000,ko02000 Pfam:SusD
HKOPHDEH_01007 8.18e-207 - - - S - - - Concanavalin A-like lectin/glucanases superfamily
HKOPHDEH_01008 0.0 - - - S - - - Putative glucoamylase
HKOPHDEH_01009 0.0 - - - S - - - Putative glucoamylase
HKOPHDEH_01010 1.47e-207 - - - S - - - Endonuclease Exonuclease phosphatase family
HKOPHDEH_01013 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKOPHDEH_01014 8.59e-144 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01015 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKOPHDEH_01016 3.52e-48 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HKOPHDEH_01018 8.71e-175 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HKOPHDEH_01019 4.18e-91 - - - S ko:K09117 - ko00000 YqeY-like protein
HKOPHDEH_01020 4.71e-300 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKOPHDEH_01021 8.11e-303 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKOPHDEH_01022 5.6e-47 gpr - - C ko:K19265 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
HKOPHDEH_01023 0.0 - 3.2.1.20 GH31 M ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG NOG06228 non supervised orthologous group
HKOPHDEH_01024 4.03e-156 - - - S - - - COG NOG26965 non supervised orthologous group
HKOPHDEH_01025 2.63e-155 - - - M - - - COG NOG27406 non supervised orthologous group
HKOPHDEH_01026 0.0 nagA - - G - - - b-glycosidase, glycoside hydrolase family 3 protein
HKOPHDEH_01027 0.0 nagA - - M - - - COG1680 Beta-lactamase class C and other penicillin binding
HKOPHDEH_01028 1.97e-108 - 3.5.99.6 - G ko:K02080,ko:K02564 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko01000 COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase
HKOPHDEH_01029 1.31e-293 gluP - - G ko:K02429 - ko00000,ko02000 Transporter, major facilitator family protein
HKOPHDEH_01030 0.0 - 3.2.1.14 GH18 G ko:K01183,ko:K09992 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 18 family
HKOPHDEH_01032 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01033 0.0 - - - S ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_01034 3.38e-119 - - - S - - - Trehalose utilisation
HKOPHDEH_01037 0.0 - - - M - - - Peptidase, M23 family
HKOPHDEH_01038 0.0 - - - M - - - Dipeptidase
HKOPHDEH_01039 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II
HKOPHDEH_01040 7.67e-203 nudC 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 COG COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding
HKOPHDEH_01041 1.55e-97 - - - L - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01042 0.0 - - - T - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_01043 1.39e-57 - - - T - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_01044 1.13e-120 chrA - - P ko:K07240 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
HKOPHDEH_01045 3.92e-129 - - - P ko:K07240 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01046 0.0 yngK - - S - - - lipoprotein YddW precursor
HKOPHDEH_01047 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_01048 3.88e-105 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKOPHDEH_01049 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKOPHDEH_01051 4.38e-102 - - - L - - - DNA-binding protein
HKOPHDEH_01052 6.05e-45 - 4.1.1.3 - C ko:K01573 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Sodium pump decarboxylase gamma subunit
HKOPHDEH_01053 1.97e-282 cfiA 6.4.1.1 - C ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG5016 Pyruvate oxaloacetate carboxyltransferase
HKOPHDEH_01054 8.84e-285 - 4.1.1.3 - C ko:K01572 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 sodium ion-translocating decarboxylase, beta subunit
HKOPHDEH_01055 1.71e-300 - - - MU - - - Psort location OuterMembrane, score
HKOPHDEH_01056 3.93e-258 - - - V - - - Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKOPHDEH_01057 1.33e-117 cobW - - S - - - CobW P47K family protein
HKOPHDEH_01058 0.0 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
HKOPHDEH_01059 8.58e-139 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKOPHDEH_01060 1.96e-49 - - - - - - - -
HKOPHDEH_01061 2.77e-128 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HKOPHDEH_01062 6.44e-187 - - - S - - - stress-induced protein
HKOPHDEH_01063 6.55e-155 yeaZ - - O ko:K14742 - ko00000,ko03016 Universal bacterial protein YeaZ
HKOPHDEH_01064 1.35e-142 - - - S - - - COG NOG11645 non supervised orthologous group
HKOPHDEH_01065 1.9e-314 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKOPHDEH_01066 2.7e-126 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKOPHDEH_01067 2.52e-135 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_01068 3.08e-57 - - - S - - - COG NOG18433 non supervised orthologous group
HKOPHDEH_01069 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 COG3250 Beta-galactosidase beta-glucuronidase
HKOPHDEH_01070 0.0 - - GH63 G ko:K03931 - ko00000 Glycoside hydrolase
HKOPHDEH_01071 0.0 - - - GM ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_01072 8.93e-301 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01073 0.0 - - - - - - - -
HKOPHDEH_01074 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01075 0.0 - - - GM ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_01076 1.5e-210 - - - M - - - COG NOG07608 non supervised orthologous group
HKOPHDEH_01077 1.56e-82 - - - M - - - COG NOG07608 non supervised orthologous group
HKOPHDEH_01082 8.9e-302 - - - S - - - Protein of unknown function (DUF2961)
HKOPHDEH_01083 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 glycosyl hydrolase, family 3
HKOPHDEH_01084 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Chitobiase/beta-hexosaminidase C-terminal domain
HKOPHDEH_01085 0.0 - 3.2.1.45 GH116 G ko:K17108 ko00511,ko00600,ko01100,map00511,map00600,map01100 ko00000,ko00001,ko01000 Pfam:GBA2_N
HKOPHDEH_01086 0.0 glnA 6.3.1.2 - S ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 Glutamate--ammonia ligase, catalytic domain protein
HKOPHDEH_01088 8.01e-162 - - - K ko:K21556 - ko00000,ko03000 - catabolite gene activator and regulatory subunit of cAMP-dependent protein
HKOPHDEH_01089 1.23e-227 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKOPHDEH_01090 1.63e-148 lolA - - M ko:K03634 - ko00000 COG NOG19151 non supervised orthologous group
HKOPHDEH_01091 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related
HKOPHDEH_01092 1.03e-140 - - - L - - - regulation of translation
HKOPHDEH_01093 8.28e-239 - - - S ko:K07133 - ko00000 Domain of unknown function (DUF4143)
HKOPHDEH_01094 6.92e-217 - - - - - - - -
HKOPHDEH_01095 3.71e-101 - - - - - - - -
HKOPHDEH_01096 8.39e-141 - - - - - - - -
HKOPHDEH_01097 8.73e-124 - - - - - - - -
HKOPHDEH_01099 5.45e-144 - - - - - - - -
HKOPHDEH_01102 1.53e-209 - - - K - - - methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family)
HKOPHDEH_01103 0.0 - - - P ko:K16089 - ko00000,ko02000 COG4771 Outer membrane receptor for ferrienterochelin and colicins
HKOPHDEH_01104 2.11e-67 - - - - - - - -
HKOPHDEH_01105 0.0 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HKOPHDEH_01106 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_01107 1.35e-281 - 3.2.1.45 GH116 G ko:K17108 ko00511,ko00600,ko01100,map00511,map00600,map01100 ko00000,ko00001,ko01000 Pfam:GBA2_N
HKOPHDEH_01108 2.84e-297 - - - S - - - COG NOG11699 non supervised orthologous group
HKOPHDEH_01109 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01110 0.0 - - - P ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_01111 3.69e-188 - - - S - - - Domain of unknown function (DUF4886)
HKOPHDEH_01112 0.0 - - - P - - - Psort location OuterMembrane, score
HKOPHDEH_01113 3.8e-291 - - - S - - - Putative binding domain, N-terminal
HKOPHDEH_01114 1.68e-263 - - - F ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 COG1864 DNA RNA endonuclease G, NUC1
HKOPHDEH_01115 0.0 - - - S - - - ATP-binding cassette protein, ChvD family
HKOPHDEH_01117 7.43e-229 aglC 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 COG3345 Alpha-galactosidase
HKOPHDEH_01118 5.41e-68 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01119 0.0 - - - S - - - SusD family
HKOPHDEH_01120 3.57e-191 - - - - - - - -
HKOPHDEH_01122 6.48e-286 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKOPHDEH_01123 0.0 - - - JM - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01124 0.0 fumB 4.2.1.2 - C ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
HKOPHDEH_01125 9.02e-99 - - - - - - - -
HKOPHDEH_01126 3.16e-13 - - - S - - - No significant database matches
HKOPHDEH_01128 5.37e-83 - - - CO - - - amine dehydrogenase activity
HKOPHDEH_01129 2.08e-113 - - - S - - - protein BT4048 SWALL AAO79153 (EMBL AE016943) (373 aa) fasta scores E()
HKOPHDEH_01130 1.2e-178 - - - E - - - non supervised orthologous group
HKOPHDEH_01131 5.91e-119 - 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HKOPHDEH_01132 2.25e-175 - - - D - - - nuclear chromosome segregation
HKOPHDEH_01133 1.36e-244 mdh 1.1.1.37 - C ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the LDH MDH superfamily
HKOPHDEH_01134 8.44e-200 yitL - - S ko:K00243 - ko00000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_01135 6.15e-169 - - - J - - - Domain of unknown function (DUF4476)
HKOPHDEH_01136 2.69e-166 - - - S - - - COG NOG36047 non supervised orthologous group
HKOPHDEH_01137 5.58e-306 - - - MU ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 Psort location OuterMembrane, score 10.00
HKOPHDEH_01138 2.85e-245 - - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKOPHDEH_01139 2.21e-295 macB_3 - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
HKOPHDEH_01140 4.84e-234 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
HKOPHDEH_01142 0.0 pafA - - P - - - type I phosphodiesterase nucleotide pyrophosphatase
HKOPHDEH_01143 1.23e-268 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_01144 7.12e-170 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HKOPHDEH_01145 1.12e-303 - - - I - - - Psort location OuterMembrane, score
HKOPHDEH_01146 1.38e-310 - - - S - - - Tetratricopeptide repeat protein
HKOPHDEH_01147 7.23e-148 - - - S - - - Lipopolysaccharide-assembly, LptC-related
HKOPHDEH_01152 2.1e-309 - - - S - - - Protein of unknown function (DUF1343)
HKOPHDEH_01153 0.0 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01154 0.0 lytB - - D ko:K06381 - ko00000 SpoIID LytB domain protein
HKOPHDEH_01155 1.33e-228 - - - F - - - Domain of unknown function (DUF4922)
HKOPHDEH_01156 0.0 - - - M - - - Glycosyltransferase, group 2 family protein
HKOPHDEH_01157 9e-133 - - - M - - - PQQ enzyme repeat
HKOPHDEH_01158 4.73e-190 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Pyridoxal kinase
HKOPHDEH_01159 1.1e-190 - - - G - - - COG COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
HKOPHDEH_01160 1.18e-76 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 Psort location Cytoplasmic, score
HKOPHDEH_01161 9.4e-133 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HKOPHDEH_01163 3.49e-18 - - - - - - - -
HKOPHDEH_01166 1.48e-118 - - - K - - - transcriptional regulator, LuxR family
HKOPHDEH_01168 2.63e-52 - - - - - - - -
HKOPHDEH_01175 1.79e-287 - - - S ko:K21571 - ko00000 Outer membrane protein SusF_SusE
HKOPHDEH_01176 0.0 susD - - M ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_01177 0.0 susC - - P ko:K21573 - ko00000,ko02000 TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01178 8.26e-179 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HKOPHDEH_01179 5.76e-45 mnmC - - S - - - Psort location Cytoplasmic, score
HKOPHDEH_01180 1.18e-104 yqaA - - S - - - Psort location CytoplasmicMembrane, score 9.46
HKOPHDEH_01181 2.83e-236 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01182 1.22e-309 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HKOPHDEH_01183 0.0 pepX2 3.4.14.5 - E ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Peptidase, S9A B C family, catalytic domain protein
HKOPHDEH_01184 8.33e-317 rlmL - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HKOPHDEH_01185 2.1e-215 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 9.97
HKOPHDEH_01188 4.13e-281 bglB 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
HKOPHDEH_01189 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HKOPHDEH_01190 8.83e-107 - 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
HKOPHDEH_01192 6.47e-146 - - - M ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_01193 3.2e-261 - - - G - - - Histidine acid phosphatase
HKOPHDEH_01194 3.01e-107 ispF 4.6.1.12 - H ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HKOPHDEH_01195 1.23e-254 - - - S - - - Ser Thr phosphatase family protein
HKOPHDEH_01196 3.85e-260 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HKOPHDEH_01197 6.47e-208 - - - S - - - COG NOG24904 non supervised orthologous group
HKOPHDEH_01198 3.72e-261 - - - P - - - phosphate-selective porin
HKOPHDEH_01200 2.67e-178 trmU 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKOPHDEH_01201 9.77e-152 narL - - K - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKOPHDEH_01202 6.18e-109 - - - S - - - COG NOG27363 non supervised orthologous group
HKOPHDEH_01203 9.84e-305 nhaC - - C ko:K03315 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01204 2.59e-276 ynfM - - EGP ko:K08224 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01205 1.86e-211 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 Histidine kinase
HKOPHDEH_01206 3.69e-201 - - - T - - - helix_turn_helix, arabinose operon control protein
HKOPHDEH_01207 1.09e-37 - - - K - - - Cro/C1-type HTH DNA-binding domain
HKOPHDEH_01208 1.39e-166 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKOPHDEH_01209 3.79e-176 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKOPHDEH_01210 6.04e-49 fjo13 - - S - - - COG NOG19122 non supervised orthologous group
HKOPHDEH_01211 8.27e-193 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily
HKOPHDEH_01212 1.97e-229 - - - H - - - Methyltransferase domain protein
HKOPHDEH_01213 4.56e-115 - - - S - - - COG NOG29882 non supervised orthologous group
HKOPHDEH_01214 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HKOPHDEH_01215 5.47e-76 - - - - - - - -
HKOPHDEH_01216 3.44e-48 - - - S - - - COG NOG34011 non supervised orthologous group
HKOPHDEH_01217 3.44e-111 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01218 2.32e-170 - - - C - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01219 4.06e-243 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01220 1.18e-295 - - - L - - - Phage integrase SAM-like domain
HKOPHDEH_01221 5.31e-204 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01222 1.19e-64 - - - - - - - -
HKOPHDEH_01223 1.99e-239 - - - - - - - -
HKOPHDEH_01224 7.99e-37 - - - - - - - -
HKOPHDEH_01225 3.21e-228 - - - T - - - cheY-homologous receiver domain
HKOPHDEH_01227 1.31e-116 - - - L - - - DNA-binding protein
HKOPHDEH_01228 5.12e-267 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HKOPHDEH_01229 2.43e-165 - - - - - - - -
HKOPHDEH_01230 2.16e-285 - - - J - - - endoribonuclease L-PSP
HKOPHDEH_01231 0.0 ccsA - - O - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01232 2.24e-140 - - - K - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKOPHDEH_01233 6.89e-168 - - - D ko:K07322 - ko00000 Hemerythrin HHE cation binding domain protein
HKOPHDEH_01234 6.16e-81 - - - K - - - Transcriptional regulator, BlaI MecI CopY family
HKOPHDEH_01235 7.71e-52 - - - CO - - - COG NOG24773 non supervised orthologous group
HKOPHDEH_01236 1.18e-47 - - - S - - - Tetratricopeptide repeat protein
HKOPHDEH_01237 3.9e-85 - - - S - - - Domain of unknown function (DUF3244)
HKOPHDEH_01240 2.61e-210 - - - S - - - Sulfatase-modifying factor enzyme 1
HKOPHDEH_01241 9.75e-301 - - - S - - - protein BT3056 SWALL AAO78162 (EMBL AE016938) (409 aa) fasta scores E()
HKOPHDEH_01242 2.48e-230 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01243 1.53e-147 yciO - - J - - - Belongs to the SUA5 family
HKOPHDEH_01244 0.0 - - - L - - - COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
HKOPHDEH_01245 2.22e-111 - - - S - - - of the HAD superfamily
HKOPHDEH_01247 2.26e-193 - - - K - - - Fic/DOC family
HKOPHDEH_01248 0.0 - - - T - - - PAS fold
HKOPHDEH_01249 8.04e-230 - - - S - - - Fimbrillin-A associated anchor proteins Mfa1 and Mfa2
HKOPHDEH_01250 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01251 0.0 - - - KT - - - COG NOG11230 non supervised orthologous group
HKOPHDEH_01252 6.72e-152 - - - C - - - WbqC-like protein
HKOPHDEH_01253 7.15e-229 lepB_1 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HKOPHDEH_01254 0.0 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 signal peptidase i
HKOPHDEH_01255 2.22e-183 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the DapB family
HKOPHDEH_01258 1.83e-185 - 1.5.1.38, 1.5.1.39 - C ko:K19285,ko:K19286 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Nitroreductase family
HKOPHDEH_01259 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKOPHDEH_01260 2.08e-189 - - - Q ko:K02067 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component
HKOPHDEH_01261 5.69e-265 amiA 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
HKOPHDEH_01263 1.33e-128 rfbC 5.1.3.13 - G ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HKOPHDEH_01264 2.66e-315 ugd 1.1.1.22 - C ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKOPHDEH_01265 9.87e-189 - - - S - - - COG NOG26711 non supervised orthologous group
HKOPHDEH_01266 6.84e-293 deaD - - L - - - Belongs to the DEAD box helicase family
HKOPHDEH_01267 7.95e-291 serB 3.1.3.3 - ET ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 Psort location Cytoplasmic, score 8.96
HKOPHDEH_01269 9.57e-99 - - - O - - - COG NOG28456 non supervised orthologous group
HKOPHDEH_01270 1.78e-265 lptG - - S ko:K11720 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Permease, YjgP YjgQ family
HKOPHDEH_01271 3.49e-70 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKOPHDEH_01272 1.58e-306 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Class II glutamine amidotransferase
HKOPHDEH_01273 4.45e-132 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related
HKOPHDEH_01274 3.24e-181 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related
HKOPHDEH_01275 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase, glutamine-hydrolyzing
HKOPHDEH_01276 3.15e-06 - - - - - - - -
HKOPHDEH_01277 2.34e-108 - - - L - - - COG NOG29624 non supervised orthologous group
HKOPHDEH_01278 2.91e-123 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKOPHDEH_01279 5.38e-120 ugd 1.1.1.22 - C ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKOPHDEH_01280 2.46e-208 lspL 5.1.3.6 - M ko:K08679 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 epimerase dehydratase
HKOPHDEH_01281 3.15e-151 - - - S - - - PD-(D/E)XK nuclease family transposase
HKOPHDEH_01282 7.62e-307 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKOPHDEH_01283 9.37e-79 - - - M - - - COG COG3209 Rhs family protein
HKOPHDEH_01284 6.22e-97 - - - M - - - COG COG3209 Rhs family protein
HKOPHDEH_01285 1.16e-129 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HKOPHDEH_01286 1.73e-161 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_01287 1.19e-176 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HKOPHDEH_01288 1.68e-78 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKOPHDEH_01289 2.29e-48 yidD - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HKOPHDEH_01290 5.61e-147 - - - L ko:K03424 - ko00000,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_01291 4.57e-55 - - - E - - - Transglutaminase-like
HKOPHDEH_01292 0.0 htrA - - O - - - Psort location Periplasmic, score
HKOPHDEH_01293 5.16e-189 rpoD - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKOPHDEH_01294 8.92e-87 - - - S - - - COG NOG31446 non supervised orthologous group
HKOPHDEH_01295 1.14e-297 - - - Q - - - Clostripain family
HKOPHDEH_01296 0.0 cdr - - P - - - Belongs to the sulfur carrier protein TusA family
HKOPHDEH_01297 6.88e-73 - - - K - - - Transcriptional regulator, MarR family
HKOPHDEH_01298 0.0 - - - S - - - Tetratricopeptide repeat protein
HKOPHDEH_01299 6.76e-139 maf - - D ko:K06287 - ko00000 COG0424 Nucleotide-binding protein implicated in inhibition of septum formation
HKOPHDEH_01300 2.82e-127 kdsC 3.1.3.45 - S ko:K03270 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family
HKOPHDEH_01301 3.87e-176 - - - S - - - NADP oxidoreductase coenzyme F420-dependent
HKOPHDEH_01302 9.32e-70 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_01303 3.4e-120 - - - C - - - Nitroreductase family
HKOPHDEH_01304 8.5e-239 - - - V - - - COG NOG22551 non supervised orthologous group
HKOPHDEH_01305 0.0 treZ_2 - - M - - - branching enzyme
HKOPHDEH_01306 6.3e-177 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01307 0.0 - - - S ko:K21572 - ko00000,ko02000 Pfam:SusD
HKOPHDEH_01308 0.0 - - - G - - - Belongs to the glycosyl hydrolase 2 family
HKOPHDEH_01310 7.18e-243 - - - PT - - - COG3712 Fe2 -dicitrate sensor, membrane component
HKOPHDEH_01311 4.28e-125 - - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog
HKOPHDEH_01312 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
HKOPHDEH_01313 4.31e-182 - 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 35 family
HKOPHDEH_01314 0.0 - - - G - - - Belongs to the glycosyl hydrolase 2 family
HKOPHDEH_01315 6.28e-271 - - - G - - - Transporter, major facilitator family protein
HKOPHDEH_01316 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HKOPHDEH_01318 0.0 - 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HKOPHDEH_01319 0.0 - - - G - - - Belongs to the glycosyl hydrolase 32 family
HKOPHDEH_01320 7.05e-110 - - - F ko:K21572 - ko00000,ko02000 COG NOG27574 non supervised orthologous group
HKOPHDEH_01321 4.01e-133 tlyC - - S ko:K03699 - ko00000,ko02042 Psort location CytoplasmicMembrane, score
HKOPHDEH_01322 0.0 ppiD 5.2.1.8 - O ko:K01802,ko:K03770 - ko00000,ko01000,ko03110 COG NOG26630 non supervised orthologous group
HKOPHDEH_01323 6.46e-246 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HKOPHDEH_01324 7.14e-256 - - - L - - - COG NOG11654 non supervised orthologous group
HKOPHDEH_01325 2.52e-263 pdxA 1.1.1.262 - C ko:K00097 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the PdxA family
HKOPHDEH_01326 7.69e-293 fhlA - - K - - - Sigma-54 interaction domain protein
HKOPHDEH_01327 0.0 - - - S ko:K07263 - ko00000,ko01000,ko01002 Belongs to the peptidase M16 family
HKOPHDEH_01328 0.0 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01329 6.97e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system ATPase component
HKOPHDEH_01330 1.25e-118 mepS 3.4.17.13 - M ko:K13694 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family
HKOPHDEH_01331 1.57e-203 - - - S ko:K09973 - ko00000 GumN protein
HKOPHDEH_01332 0.0 - - - T - - - COG COG0642 Signal transduction histidine kinase
HKOPHDEH_01333 4.48e-54 - - - G - - - Alpha-1,2-mannosidase
HKOPHDEH_01334 0.0 - 3.2.1.31 - G ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolases family 2, TIM barrel domain
HKOPHDEH_01335 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01336 0.0 - - - F ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_01337 9.71e-90 - - - - - - - -
HKOPHDEH_01338 4.94e-19 - - - S - - - Domain of unknown function (DUF4466)
HKOPHDEH_01340 0.0 - - - - - - - -
HKOPHDEH_01341 1e-173 - - - S - - - Fimbrillin-like
HKOPHDEH_01342 2.42e-190 - - - S - - - COG NOG26135 non supervised orthologous group
HKOPHDEH_01343 7.18e-256 - - - M - - - Protein of unknown function (DUF3575)
HKOPHDEH_01344 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_01345 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01347 1.01e-47 ramA_2 - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01348 0.0 - - - P ko:K08138 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKOPHDEH_01349 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_01350 0.0 xylB_2 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Carbohydrate kinase, FGGY family protein
HKOPHDEH_01351 4.29e-171 - - - F - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01352 1.29e-260 - - - PT - - - Sigma factor regulatory protein, FecR PupR family
HKOPHDEH_01353 4.64e-129 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor, ECF subfamily
HKOPHDEH_01354 0.0 - - - T ko:K07713 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
HKOPHDEH_01355 7.19e-197 ppiA 5.2.1.8 - M ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKOPHDEH_01356 5.71e-302 - - - S ko:K07263 - ko00000,ko01000,ko01002 Peptidase M16 inactive domain protein
HKOPHDEH_01357 1.7e-314 norM - - V ko:K03327 - ko00000,ko02000 MATE efflux family protein
HKOPHDEH_01359 1.62e-226 - 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 9.97
HKOPHDEH_01360 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_01361 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_01362 4.63e-88 - - - S - - - Psort location Cytoplasmic, score
HKOPHDEH_01364 0.0 cepA 2.4.1.20 GT36 G ko:K00702 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Putative carbohydrate binding domain
HKOPHDEH_01365 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 hydrolase family 2, sugar binding
HKOPHDEH_01366 1.59e-213 - - - K - - - Transcriptional regulator, AraC family
HKOPHDEH_01368 0.0 - - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
HKOPHDEH_01370 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_01371 7.07e-130 - - - S - - - Metallo-beta-lactamase superfamily
HKOPHDEH_01372 1.04e-263 - - - S ko:K09704 - ko00000 Conserved protein
HKOPHDEH_01373 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01374 0.0 - - - F ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_01375 1.15e-279 - - - S ko:K21571 - ko00000 SusE outer membrane protein
HKOPHDEH_01376 1.04e-59 - - - S - - - Tetratricopeptide repeat protein
HKOPHDEH_01377 2.56e-108 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
HKOPHDEH_01378 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
HKOPHDEH_01379 0.0 abf2 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase domain protein
HKOPHDEH_01380 0.0 araB - - G - - - Carbohydrate kinase, FGGY family protein
HKOPHDEH_01381 4.53e-157 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HKOPHDEH_01382 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HKOPHDEH_01383 5.67e-286 - - - M - - - Glycosyl hydrolases family 43
HKOPHDEH_01384 0.0 - - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 DNA mismatch repair protein
HKOPHDEH_01385 7.3e-168 - - - K ko:K02081 - ko00000,ko03000 DeoR C terminal sensor domain
HKOPHDEH_01386 2.84e-143 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HKOPHDEH_01387 0.0 - 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 35 family
HKOPHDEH_01388 1.66e-289 uxuA 4.2.1.8 - H ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
HKOPHDEH_01389 4.98e-137 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG COG2818 3-methyladenine DNA glycosylase
HKOPHDEH_01390 1.47e-285 - - - G - - - Glycosyl hydrolases family 43
HKOPHDEH_01392 1.73e-191 - - - - - - - -
HKOPHDEH_01394 3.61e-138 fklB 5.2.1.8 - G ko:K03772,ko:K03773 - ko00000,ko01000,ko03110 Peptidyl-prolyl cis-trans isomerase
HKOPHDEH_01395 3.98e-169 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HKOPHDEH_01396 5.64e-174 - - - S - - - Glycosyltransferase, group 2 family protein
HKOPHDEH_01397 0.0 - - - M - - - Glycosyltransferase, group 1 family protein
HKOPHDEH_01398 4.46e-257 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01399 2.57e-220 - - - M ko:K07271 - ko00000,ko01000 LicD family
HKOPHDEH_01400 3.83e-229 - - - S - - - Core-2 I-Branching enzyme
HKOPHDEH_01401 9.49e-89 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_01402 0.0 - - - H - - - Psort location OuterMembrane, score
HKOPHDEH_01403 9.4e-41 - - - H - - - Psort location OuterMembrane, score
HKOPHDEH_01404 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKOPHDEH_01405 3.7e-128 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HKOPHDEH_01406 5.27e-189 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01407 2.5e-258 wecB 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKOPHDEH_01408 6.65e-149 yadS - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01409 0.0 - - - S - - - Peptidase M16 inactive domain
HKOPHDEH_01410 3.34e-117 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HKOPHDEH_01412 3.49e-131 - - - M - - - COG NOG27749 non supervised orthologous group
HKOPHDEH_01413 5.36e-122 - - - K - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01414 1.63e-179 ric - - C ko:K07322 - ko00000 Di-iron-containing protein involved in the repair of iron-sulfur clusters
HKOPHDEH_01415 1.61e-85 - - - S - - - Protein of unknown function, DUF488
HKOPHDEH_01416 0.0 - - - L - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01417 9.33e-48 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01418 3.01e-126 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Conserved protein
HKOPHDEH_01419 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
HKOPHDEH_01420 3.82e-128 ogt 2.1.1.63 - H ko:K00567,ko:K10778 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKOPHDEH_01421 9.04e-214 - - - K - - - Transcriptional regulator
HKOPHDEH_01422 6.62e-296 - - - MU - - - COG NOG26656 non supervised orthologous group
HKOPHDEH_01423 1.29e-203 - - - M ko:K01993 - ko00000 COG COG0845 Membrane-fusion protein
HKOPHDEH_01425 5.5e-265 romA - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01426 6.51e-215 - - - G - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01427 0.0 hcp 1.7.99.1 - C ko:K05601 ko00910,map00910 ko00000,ko00001,ko01000 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O
HKOPHDEH_01428 6.37e-144 - - - K - - - - catabolite gene activator and regulatory subunit of cAMP-dependent protein
HKOPHDEH_01429 5.42e-158 - - - K - - - COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HKOPHDEH_01430 2.35e-248 - - - M - - - COG NOG37029 non supervised orthologous group
HKOPHDEH_01431 0.0 wcaJ_2 2.7.8.6 - M ko:K00996,ko:K03606 ko05111,map05111 ko00000,ko00001,ko01000,ko01005 Psort location CytoplasmicMembrane, score
HKOPHDEH_01432 1.02e-186 - - - M ko:K01991 ko02026,map02026 ko00000,ko00001,ko02000 COG1596 Periplasmic protein involved in polysaccharide export
HKOPHDEH_01433 0.0 ptk_3 - - DM - - - Chain length determinant protein
HKOPHDEH_01434 3.55e-127 - - - K - - - Transcription termination antitermination factor NusG
HKOPHDEH_01435 6.23e-111 - 3.5.1.28 - V ko:K01447 - ko00000,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_01436 2.35e-08 - - - - - - - -
HKOPHDEH_01437 4.8e-116 - - - L - - - DNA-binding protein
HKOPHDEH_01438 1.38e-103 - - - MP ko:K06079 ko01503,map01503 ko00000,ko00001 COG NOG29769 non supervised orthologous group
HKOPHDEH_01439 2.79e-293 corC_1 - - P ko:K03699 - ko00000,ko02042 Psort location CytoplasmicMembrane, score
HKOPHDEH_01440 1.35e-201 - 3.1.2.12 CE1 S ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 ko00000,ko00001,ko01000 esterase
HKOPHDEH_01441 2.6e-215 - - - S - - - COG NOG30864 non supervised orthologous group
HKOPHDEH_01442 8.42e-226 - - - M - - - peptidase S41
HKOPHDEH_01443 1.34e-99 - - - M - - - peptidase S41
HKOPHDEH_01444 8.28e-310 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_01445 4.27e-126 rpoE - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HKOPHDEH_01446 2.14e-69 - - - S - - - Domain of unknown function (DUF5056)
HKOPHDEH_01447 2.43e-288 cls - - M ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HKOPHDEH_01448 2.84e-200 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKOPHDEH_01449 1.01e-111 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKOPHDEH_01450 8.67e-111 asnC - - K ko:K03718 - ko00000,ko03000 transcriptional regulator, AsnC family
HKOPHDEH_01451 0.0 - - - S - - - IgA Peptidase M64
HKOPHDEH_01452 7.47e-133 - - - K - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01453 2.62e-89 - - - U ko:K03559 - ko00000,ko02000 COG NOG14448 non supervised orthologous group
HKOPHDEH_01454 7.82e-71 - - - U - - - COG NOG14449 non supervised orthologous group
HKOPHDEH_01455 4.01e-161 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKOPHDEH_01456 0.0 iorA 1.2.7.8 - C ko:K00179 - br01601,ko00000,ko01000 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
HKOPHDEH_01457 1.17e-132 iorB 1.2.7.8 - C ko:K00180 - br01601,ko00000,ko01000 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
HKOPHDEH_01458 1.34e-314 paaK 6.2.1.30 - H ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 ko00000,ko00001,ko01000 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HKOPHDEH_01459 8.76e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKOPHDEH_01460 2.13e-36 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HKOPHDEH_01461 5.24e-128 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKOPHDEH_01462 6.58e-172 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKOPHDEH_01465 1.61e-132 - - - - - - - -
HKOPHDEH_01466 2.68e-17 - - - - - - - -
HKOPHDEH_01467 1.23e-29 - - - K - - - Helix-turn-helix domain
HKOPHDEH_01468 1.88e-62 - - - S - - - Helix-turn-helix domain
HKOPHDEH_01469 1.97e-119 - - - C - - - Flavodoxin
HKOPHDEH_01470 2.11e-273 - - - S ko:K06889 - ko00000 of the alpha beta superfamily
HKOPHDEH_01471 2.42e-263 - - - S - - - COG NOG15865 non supervised orthologous group
HKOPHDEH_01472 9.58e-267 - - - S - - - NPCBM-associated, NEW3 domain of alpha-galactosidase
HKOPHDEH_01473 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_01474 0.0 rluA 5.4.99.28, 5.4.99.29 - J ko:K06177 - ko00000,ko01000,ko03009,ko03016 Pseudouridine synthase, RluA family
HKOPHDEH_01475 3.98e-108 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase, gnat family
HKOPHDEH_01476 3.82e-91 gloA 4.4.1.5 - E ko:K01759,ko:K03827 ko00620,map00620 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_01477 1.93e-206 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKOPHDEH_01478 4.72e-76 ogt 2.1.1.63 - L ko:K00567,ko:K07443 - ko00000,ko01000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
HKOPHDEH_01479 1.08e-72 - - - S - - - COG NOG29454 non supervised orthologous group
HKOPHDEH_01480 1.36e-126 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 COG0440 Acetolactate synthase, small (regulatory) subunit
HKOPHDEH_01481 0.0 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetolactate synthase, large subunit
HKOPHDEH_01482 0.0 ilvD 4.2.1.9 - H ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
HKOPHDEH_01483 7.32e-130 slyD 5.2.1.8 - G ko:K03775 - ko00000,ko01000,ko03110 Psort location Cytoplasmic, score
HKOPHDEH_01484 1.57e-297 - - - S - - - Belongs to the UPF0597 family
HKOPHDEH_01485 5.95e-84 - - - S - - - Psort location CytoplasmicMembrane, score 9.46
HKOPHDEH_01486 0.0 arnT - - M - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01487 3.56e-131 - - - H ko:K06950 - ko00000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_01489 0.0 - - - M - - - Psort location OuterMembrane, score 9.49
HKOPHDEH_01490 9.51e-168 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKOPHDEH_01491 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_01492 3.03e-257 - - - K ko:K02529 - ko00000,ko03000 Psort location Cytoplasmic, score
HKOPHDEH_01493 1.95e-248 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Kinase, PfkB family
HKOPHDEH_01494 2.87e-54 - - - S - - - 23S rRNA-intervening sequence protein
HKOPHDEH_01495 8.09e-161 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
HKOPHDEH_01498 1.51e-260 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01499 1.65e-205 - - - IQ - - - Oxidoreductase, short chain dehydrogenase reductase family protein
HKOPHDEH_01500 2.39e-109 - - - M - - - Psort location CytoplasmicMembrane, score 9.46
HKOPHDEH_01501 1.32e-63 clpS - - S ko:K06891 - ko00000 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HKOPHDEH_01502 0.0 clpA - - O ko:K03694 - ko00000,ko03110 Belongs to the ClpA ClpB family
HKOPHDEH_01503 3.73e-163 aat 2.3.2.6 - O ko:K00684 - ko00000,ko01000 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HKOPHDEH_01504 5.71e-146 trkA - - C ko:K03499 - ko00000,ko02000 COG0569 K transport systems NAD-binding component
HKOPHDEH_01505 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01506 3.75e-86 - - - - - - - -
HKOPHDEH_01507 2.07e-73 nuoA 1.6.5.3 - C ko:K00330 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKOPHDEH_01508 2.37e-141 nuoB 1.6.5.3 - C ko:K00331 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKOPHDEH_01509 0.0 nuoC 1.6.5.3 - C ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKOPHDEH_01510 2.81e-258 nuoH 1.6.5.3 - C ko:K00337 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HKOPHDEH_01511 5.13e-148 - - - M - - - Protein of unknown function (DUF3575)
HKOPHDEH_01513 4.24e-205 - - - L - - - Belongs to the 'phage' integrase family
HKOPHDEH_01514 1.82e-179 tyrA 1.3.1.12 - E ko:K00210 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HKOPHDEH_01515 1.24e-258 pheB 5.4.99.5 - E ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_01516 1.86e-286 dapL 2.6.1.83 - E ko:K10206,ko:K14261 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 COG0436 Aspartate tyrosine aromatic aminotransferase
HKOPHDEH_01517 5.44e-38 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_01520 2.91e-235 - - - K ko:K21572 - ko00000,ko02000 PFAM RagB SusD
HKOPHDEH_01521 3.89e-306 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01522 0.0 - - - P - - - COG COG3119 Arylsulfatase A and related enzymes
HKOPHDEH_01523 0.0 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 Psort location CytoplasmicMembrane, score
HKOPHDEH_01524 0.0 - - - P - - - Psort location OuterMembrane, score
HKOPHDEH_01525 2.55e-192 fcl 1.1.1.271 - GM ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
HKOPHDEH_01528 0.0 - - - T ko:K02481 - ko00000,ko02022 acetoacetate metabolism regulatory protein AtoC K07714
HKOPHDEH_01529 0.0 - - - MU - - - Psort location OuterMembrane, score
HKOPHDEH_01530 2.84e-115 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_01531 0.0 mmdA - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HKOPHDEH_01532 9.72e-166 - - - K - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKOPHDEH_01533 4.18e-195 - - - - - - - -
HKOPHDEH_01534 2.97e-142 - - - S - - - COG NOG28927 non supervised orthologous group
HKOPHDEH_01535 1.17e-217 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKOPHDEH_01536 0.0 uvrD2 - - L - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01537 2.29e-197 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKOPHDEH_01538 1.51e-42 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKOPHDEH_01540 1.08e-249 - - - M - - - Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKOPHDEH_01541 0.0 - - - M - - - Efflux transporter, outer membrane factor lipoprotein, NodT family
HKOPHDEH_01542 5.69e-189 - - - S - - - COG NOG19137 non supervised orthologous group
HKOPHDEH_01543 3.75e-288 - - - S - - - non supervised orthologous group
HKOPHDEH_01545 2.21e-164 mtnN 3.2.2.9 - F ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKOPHDEH_01546 0.0 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01547 7.85e-69 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKOPHDEH_01548 1.12e-287 lolE - - M ko:K09808,ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4591 ABC-type transport system, involved in lipoprotein release, permease component
HKOPHDEH_01549 2.43e-151 mdmC 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_01550 6.05e-49 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase
HKOPHDEH_01554 9.76e-229 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HKOPHDEH_01555 5.07e-108 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Involved in allosteric regulation of aspartate carbamoyltransferase
HKOPHDEH_01556 8.45e-61 - - - S - - - COG COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HKOPHDEH_01557 3.29e-186 - - - S - - - COG NOG27381 non supervised orthologous group
HKOPHDEH_01558 1.49e-311 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKOPHDEH_01559 3.26e-47 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formyltetrahydrofolate synthetase
HKOPHDEH_01561 0.0 - 2.7.11.1 - KLT ko:K08838,ko:K12132 - ko00000,ko01000,ko01001,ko04131 Protein tyrosine kinase
HKOPHDEH_01562 2.79e-178 - - - S - - - Putative binding domain, N-terminal
HKOPHDEH_01563 5.17e-145 - - - S - - - Double zinc ribbon
HKOPHDEH_01564 0.0 - 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HKOPHDEH_01565 1.36e-197 - - - E ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_01566 1.26e-80 - - - S - - - Domain of unknown function (DUF4945)
HKOPHDEH_01567 0.0 - - - G - - - Domain of unknown function (DUF4185)
HKOPHDEH_01568 0.0 - - - - - - - -
HKOPHDEH_01569 0.0 - 3.2.1.45 GH116 G ko:K17108 ko00511,ko00600,ko01100,map00511,map00600,map01100 ko00000,ko00001,ko01000 Pfam:GBA2_N
HKOPHDEH_01571 1.5e-64 - - - S - - - Stress responsive A B barrel domain
HKOPHDEH_01572 1.65e-140 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_01573 0.0 mltF - - M ko:K18691 - ko00000,ko01000,ko01011 soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein
HKOPHDEH_01574 2.16e-134 metH 2.1.1.13 - E ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_01575 0.0 metH 2.1.1.13 - E ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_01576 3.34e-79 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKOPHDEH_01577 9.37e-202 - - - P - - - COG COG3119 Arylsulfatase A and related enzymes
HKOPHDEH_01578 0.0 - - - S - - - PHP domain protein
HKOPHDEH_01579 1.28e-203 ppgK 2.7.1.2, 2.7.1.63 - GK ko:K00845,ko:K00886 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 9.26
HKOPHDEH_01580 1.28e-277 - - - G - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01583 0.0 bglX 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 glycosyl hydrolase, family 3
HKOPHDEH_01584 0.0 - - - KT - - - COG NOG11230 non supervised orthologous group
HKOPHDEH_01585 4.09e-64 - - - KT - - - COG NOG11230 non supervised orthologous group
HKOPHDEH_01586 2.48e-40 - - - P - - - Psort location OuterMembrane, score
HKOPHDEH_01587 8.65e-263 - - - S - - - COG NOG28036 non supervised orthologous group
HKOPHDEH_01588 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Psort location Cytoplasmic, score
HKOPHDEH_01589 1.7e-50 hupB - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKOPHDEH_01590 2.06e-161 - 3.4.21.105 - S ko:K09650 - ko00000,ko01000,ko01002,ko03029 Psort location CytoplasmicMembrane, score
HKOPHDEH_01591 2.23e-204 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01593 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01594 3.15e-303 - - - S - - - Protein of unknown function (DUF2961)
HKOPHDEH_01595 5.52e-229 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_01598 9.76e-22 - - - - - - - -
HKOPHDEH_01599 3.1e-79 - - - S - - - Protein of unknown function (DUF3795)
HKOPHDEH_01600 7.21e-191 - - - Q - - - COG NOG10855 non supervised orthologous group
HKOPHDEH_01601 5.7e-200 - - - K - - - Helix-turn-helix domain
HKOPHDEH_01602 1.86e-237 - - - G - - - COG2407 L-fucose isomerase and related
HKOPHDEH_01603 0.0 - - - T - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_01604 6.29e-143 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HKOPHDEH_01605 8.4e-121 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HKOPHDEH_01606 1.27e-288 - - - V - - - MacB-like periplasmic core domain
HKOPHDEH_01607 4.64e-75 - - - V ko:K02004 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
HKOPHDEH_01608 6.29e-219 rnfC - - C ko:K03615 - ko00000 Part of a membrane complex involved in electron transport
HKOPHDEH_01609 3.27e-230 rnfD - - C ko:K03614 - ko00000 Part of a membrane complex involved in electron transport
HKOPHDEH_01610 4.24e-142 rnfG - - C ko:K03612 - ko00000 Part of a membrane complex involved in electron transport
HKOPHDEH_01611 1.89e-121 rnfE - - C ko:K03613 - ko00000 Part of a membrane complex involved in electron transport
HKOPHDEH_01612 1.39e-120 rnfA - - C ko:K03617 - ko00000 Part of a membrane complex involved in electron transport
HKOPHDEH_01613 1.42e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HKOPHDEH_01615 1.67e-78 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HKOPHDEH_01616 2.8e-173 trmH 2.1.1.185 - J ko:K03218,ko:K03437 - ko00000,ko01000,ko03009,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKOPHDEH_01617 0.0 - - - O - - - COG COG0457 FOG TPR repeat
HKOPHDEH_01618 2.08e-79 ridA 3.5.99.10 - J ko:K09022 - ko00000,ko01000 endoribonuclease L-PSP
HKOPHDEH_01619 2.52e-201 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Folylpolyglutamate synthase
HKOPHDEH_01620 1.62e-60 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Folylpolyglutamate synthase
HKOPHDEH_01621 0.0 ybeZ_1 - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
HKOPHDEH_01622 3.5e-106 - - - S - - - Oxidoreductase, NAD-binding domain protein
HKOPHDEH_01623 0.0 nhaA - - P ko:K03455 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01624 7.29e-292 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis bifunctional protein HisB
HKOPHDEH_01625 3.27e-103 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKOPHDEH_01626 1.38e-128 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKOPHDEH_01627 6.52e-221 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKOPHDEH_01628 0.0 - - - S - - - Tetratricopeptide repeat protein
HKOPHDEH_01629 1.4e-51 - - - H - - - Psort location OuterMembrane, score
HKOPHDEH_01630 5.24e-307 - - - H - - - Psort location OuterMembrane, score
HKOPHDEH_01631 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKOPHDEH_01632 7.16e-71 - 2.3.1.19, 2.3.1.8 - C ko:K00625,ko:K00634 ko00430,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00650,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_01633 9.87e-263 buk 2.7.2.7 - H ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
HKOPHDEH_01634 0.0 ygjK - GH63 G ko:K03931 - ko00000 Glycoside hydrolase
HKOPHDEH_01635 2.14e-57 ygjK - GH63 G ko:K03931 - ko00000 Glycoside hydrolase
HKOPHDEH_01636 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 COG3250 Beta-galactosidase beta-glucuronidase
HKOPHDEH_01637 3.42e-157 - - - S - - - B3 4 domain protein
HKOPHDEH_01638 2.7e-172 nlpD_2 - - M - - - COG COG0739 Membrane proteins related to metalloendopeptidases
HKOPHDEH_01639 8.54e-223 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein
HKOPHDEH_01640 9.35e-226 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HKOPHDEH_01641 5.67e-177 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKOPHDEH_01642 1.75e-134 - - - - - - - -
HKOPHDEH_01643 2.71e-25 aroE 1.1.1.25 - C ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 COG0169 Shikimate 5-dehydrogenase
HKOPHDEH_01644 8.86e-133 aroE 1.1.1.25 - C ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 COG0169 Shikimate 5-dehydrogenase
HKOPHDEH_01645 1.42e-245 - - - S ko:K06889 - ko00000 of the alpha beta superfamily
HKOPHDEH_01646 0.0 - - - N - - - COG NOG14601 non supervised orthologous group
HKOPHDEH_01647 6.24e-78 - - - - - - - -
HKOPHDEH_01648 8.64e-276 - - - S ko:K06921 - ko00000 ATPase (AAA superfamily)
HKOPHDEH_01650 3.71e-32 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01651 0.000621 - - - S - - - Nucleotidyltransferase domain
HKOPHDEH_01652 0.0 dxs2 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKOPHDEH_01653 1.76e-301 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HKOPHDEH_01654 1.26e-203 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01657 0.0 fusA2 - - J ko:K02355 - ko00000,ko03012,ko03029 Psort location Cytoplasmic, score 9.26
HKOPHDEH_01658 0.0 rprX 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 two-component regulatory system, sensor kinase protein
HKOPHDEH_01659 3.54e-165 rprY - - K - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKOPHDEH_01660 5.66e-29 - - - - - - - -
HKOPHDEH_01661 3.21e-99 ohrR - - K - - - Transcriptional regulator, MarR family
HKOPHDEH_01662 5.98e-72 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HKOPHDEH_01663 9.62e-99 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 glycosyl hydrolase, family 3
HKOPHDEH_01664 3.02e-276 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG2706 3-carboxymuconate cyclase
HKOPHDEH_01665 4.55e-245 - - - S - - - COG NOG25792 non supervised orthologous group
HKOPHDEH_01666 4.66e-84 pqqD - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01667 0.0 - - - G - - - Transporter, major facilitator family protein
HKOPHDEH_01668 1.36e-66 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
HKOPHDEH_01669 6.52e-173 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01670 2.26e-69 lptE - - S - - - COG NOG14471 non supervised orthologous group
HKOPHDEH_01672 0.0 yicJ_1 - - G ko:K03292 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01673 2.64e-287 - 2.4.1.281 - G ko:K16212 - ko00000,ko01000 Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
HKOPHDEH_01674 2.95e-270 - 3.2.1.78 GH26 G ko:K01218,ko:K19355 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
HKOPHDEH_01675 2.41e-309 - - - U - - - WD40-like Beta Propeller Repeat
HKOPHDEH_01676 4.97e-86 - - - S - - - COG NOG31702 non supervised orthologous group
HKOPHDEH_01677 2.12e-95 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HKOPHDEH_01678 3.41e-232 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKOPHDEH_01679 1.07e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKOPHDEH_01680 1.01e-86 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKOPHDEH_01681 1.77e-81 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKOPHDEH_01682 1.06e-18 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HKOPHDEH_01683 1.98e-44 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKOPHDEH_01684 5.08e-195 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Psort location Cytoplasmic, score
HKOPHDEH_01685 7.07e-263 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKOPHDEH_01687 0.0 - - - - - - - -
HKOPHDEH_01688 0.0 - 5.1.3.11 - M ko:K16213 - ko00000,ko01000 Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)
HKOPHDEH_01689 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HKOPHDEH_01690 1.45e-46 - - - - - - - -
HKOPHDEH_01692 6.37e-125 - - - CO - - - Redoxin family
HKOPHDEH_01693 1.05e-172 cypM_1 - - H - - - Methyltransferase domain protein
HKOPHDEH_01694 4.09e-32 - - - - - - - -
HKOPHDEH_01695 2.83e-91 gloA 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_01696 1.46e-261 - - - S - - - COG NOG25895 non supervised orthologous group
HKOPHDEH_01697 6.65e-180 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01698 3.06e-115 - 6.4.1.1 - I ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Biotin-requiring enzyme
HKOPHDEH_01699 0.0 accC 6.3.4.14, 6.4.1.2, 6.4.1.3 - I ko:K01961,ko:K01965 ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
HKOPHDEH_01700 0.0 - - - H - - - Psort location OuterMembrane, score
HKOPHDEH_01702 1.52e-269 phoA 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HKOPHDEH_01703 0.0 - - - G - - - Glycosyl hydrolase family 63 C-terminal domain
HKOPHDEH_01704 0.0 - - - S ko:K09704 - ko00000 Conserved protein
HKOPHDEH_01706 5.93e-248 - - - S ko:K06885 - ko00000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_01707 1.28e-161 lpxD 2.3.1.191 - M ko:K02536 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HKOPHDEH_01708 0.0 fabZ 3.5.1.108, 4.2.1.59 - IM ko:K16363 ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
HKOPHDEH_01709 4.85e-148 lpxA 2.3.1.129 - M ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 ko00000,ko00001,ko00002,ko01000,ko01005 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HKOPHDEH_01710 4.45e-128 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01711 4.11e-223 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKOPHDEH_01712 2.94e-235 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01713 1.08e-199 - - - I - - - Acyl-transferase
HKOPHDEH_01714 1.22e-116 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HKOPHDEH_01715 3.34e-117 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HKOPHDEH_01716 0.0 - - - S ko:K09704 - ko00000 Conserved protein
HKOPHDEH_01717 2.13e-111 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HKOPHDEH_01718 0.0 - 6.2.1.3 - IQ ko:K01897,ko:K18660 ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HKOPHDEH_01719 9.51e-47 - - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKOPHDEH_01720 5.84e-226 - - - G - - - Transketolase, pyrimidine binding domain
HKOPHDEH_01721 3.43e-184 - - - G - - - Transketolase, thiamine diphosphate binding domain
HKOPHDEH_01722 2.45e-164 fabG_2 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
HKOPHDEH_01723 4.32e-142 - - - M - - - involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HKOPHDEH_01725 1.02e-233 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
HKOPHDEH_01726 1.58e-207 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKOPHDEH_01727 7.25e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKOPHDEH_01728 4.47e-182 - 3.1.6.6 - P ko:K01133 - ko00000,ko01000 COG COG3119 Arylsulfatase A and related enzymes
HKOPHDEH_01729 2.71e-72 - - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
HKOPHDEH_01730 1.39e-278 hydF - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01731 0.0 hydG 4.1.99.19 - C ko:K03150 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Iron-only hydrogenase maturation rSAM protein HydG
HKOPHDEH_01732 9.67e-250 hydE 2.8.1.6 - C ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Iron-only hydrogenase maturation rSAM protein HydE
HKOPHDEH_01733 4.85e-297 - - - C - - - 4Fe-4S binding domain protein
HKOPHDEH_01734 8.22e-214 - - - G - - - Domain of unknown function (DUF3473)
HKOPHDEH_01735 2.34e-141 pglC - - M - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_01736 5.45e-133 - - - S - - - Metallo-beta-lactamase superfamily
HKOPHDEH_01737 4.52e-301 pglE - - E - - - Belongs to the DegT DnrJ EryC1 family
HKOPHDEH_01738 3.75e-109 - - - L - - - DNA-binding protein
HKOPHDEH_01739 8.9e-11 - - - - - - - -
HKOPHDEH_01740 9.2e-168 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Psort location Cytoplasmic, score
HKOPHDEH_01741 2.42e-285 nspC 4.1.1.96 - E ko:K13747 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_01742 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HKOPHDEH_01743 9.64e-142 sodB 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HKOPHDEH_01744 3.6e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Thiamine monophosphate synthase TENI
HKOPHDEH_01746 8.03e-61 ppdK 2.7.9.1 - G ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the PEP-utilizing enzyme family
HKOPHDEH_01747 0.0 - - - G - - - Glycosyl hydrolase family 9
HKOPHDEH_01748 0.0 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01750 3.19e-90 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl-hydrolase 97 C-terminal, oligomerisation
HKOPHDEH_01751 0.0 - - - G - - - Glycosyl hydrolase family 92
HKOPHDEH_01752 4.51e-118 - - - L - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01753 0.0 - - - G - - - Glycosyl hydrolases family 28
HKOPHDEH_01754 1.49e-45 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 glycosyl hydrolase, family 3
HKOPHDEH_01756 2.79e-254 - 4.1.1.81 - E ko:K04720 ko00860,map00860 ko00000,ko00001,ko01000 COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase
HKOPHDEH_01757 0.0 cobQ 6.3.5.10 - H ko:K02232 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HKOPHDEH_01758 0.0 - - - MU - - - Psort location OuterMembrane, score
HKOPHDEH_01759 8.17e-220 - - - M ko:K01993 - ko00000 Auxiliary transport protein, membrane fusion protein
HKOPHDEH_01760 2.95e-190 - 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HKOPHDEH_01761 1.27e-60 - - - S - - - COG NOG38282 non supervised orthologous group
HKOPHDEH_01762 2.69e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKOPHDEH_01763 3.04e-138 - - - S - - - Tetratricopeptide repeat protein
HKOPHDEH_01764 9.28e-118 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HKOPHDEH_01767 7.22e-60 - - - - - - - -
HKOPHDEH_01768 7.37e-133 - - - T - - - Cyclic nucleotide-binding domain protein
HKOPHDEH_01770 4.43e-272 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HKOPHDEH_01771 0.0 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HKOPHDEH_01772 1.08e-217 ddh 1.4.1.16 - E ko:K03340 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HKOPHDEH_01773 3.47e-117 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKOPHDEH_01774 6.39e-242 - - - S - - - COG NOG26961 non supervised orthologous group
HKOPHDEH_01775 5.06e-46 pepQ 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 xaa-pro dipeptidase K01271
HKOPHDEH_01776 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
HKOPHDEH_01777 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 COG NOG04002 non supervised orthologous group
HKOPHDEH_01778 4.59e-279 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 COG NOG04002 non supervised orthologous group
HKOPHDEH_01779 0.0 - - - G - - - cog cog3537
HKOPHDEH_01780 2.72e-69 - - - M ko:K03286 - ko00000,ko02000 OmpA family
HKOPHDEH_01781 2.01e-185 - - - S - - - Exopolysaccharide biosynthesis protein YbjH
HKOPHDEH_01782 1.14e-91 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKOPHDEH_01783 1.54e-124 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKOPHDEH_01784 1.51e-215 - - - S - - - COG COG0457 FOG TPR repeat
HKOPHDEH_01786 5.63e-195 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HKOPHDEH_01787 1.61e-88 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HKOPHDEH_01788 8.8e-264 - - - O - - - Antioxidant, AhpC TSA family
HKOPHDEH_01789 1.3e-237 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_01792 0.0 rumA 2.1.1.190 - H ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKOPHDEH_01793 6.28e-219 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HKOPHDEH_01795 6.15e-96 - - - - - - - -
HKOPHDEH_01796 1.01e-100 - - - - - - - -
HKOPHDEH_01797 1.92e-21 - - - L - - - Belongs to the 'phage' integrase family
HKOPHDEH_01798 1.15e-98 - - - L - - - Belongs to the 'phage' integrase family
HKOPHDEH_01800 7.52e-263 - - - S - - - Endonuclease Exonuclease phosphatase family protein
HKOPHDEH_01801 3.84e-232 hprA 1.1.1.29 - C ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKOPHDEH_01802 7.3e-306 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HKOPHDEH_01803 0.0 - - - M - - - COG NOG06397 non supervised orthologous group
HKOPHDEH_01804 0.0 - - - G - - - Fibronectin type III-like domain
HKOPHDEH_01805 3.97e-224 - - - S ko:K21572 - ko00000,ko02000 Pfam:SusD
HKOPHDEH_01806 8.15e-196 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01808 7.4e-182 - - - O - - - COG COG3187 Heat shock protein
HKOPHDEH_01809 2.62e-125 - - - T - - - - catabolite gene activator and regulatory subunit of cAMP-dependent protein
HKOPHDEH_01810 1.26e-66 - - - V - - - COG0534 Na -driven multidrug efflux pump
HKOPHDEH_01811 1.5e-229 - - - V - - - COG0534 Na -driven multidrug efflux pump
HKOPHDEH_01815 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKOPHDEH_01816 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Cell division protein FtsI penicillin-binding protein
HKOPHDEH_01817 3.3e-70 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01818 6.14e-165 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKOPHDEH_01819 2.09e-267 - - - K - - - COG NOG25837 non supervised orthologous group
HKOPHDEH_01820 5.08e-136 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HKOPHDEH_01821 1.23e-161 - - - - - - - -
HKOPHDEH_01822 2.68e-160 - - - - - - - -
HKOPHDEH_01823 1.15e-199 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
HKOPHDEH_01824 3.96e-89 - - - S - - - COG NOG32209 non supervised orthologous group
HKOPHDEH_01825 6.46e-116 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKOPHDEH_01826 1.49e-165 fkp - - S - - - GHMP kinase, N-terminal domain protein
HKOPHDEH_01827 1.58e-207 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKOPHDEH_01828 3.16e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HKOPHDEH_01829 6.38e-184 metN - - Q ko:K02065 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HKOPHDEH_01830 8.76e-162 mlaE - - Q ko:K02066 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01831 1.39e-195 lptB - - S ko:K06861 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Psort location Cytoplasmic, score 9.12
HKOPHDEH_01832 6.63e-52 - - - S - - - COG COG0724 RNA-binding proteins (RRM domain)
HKOPHDEH_01833 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
HKOPHDEH_01834 2.77e-293 nagZ3 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
HKOPHDEH_01836 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01837 0.0 - - - KT - - - COG NOG11230 non supervised orthologous group
HKOPHDEH_01838 8.12e-306 - - - U - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01839 0.0 cca 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 tRNA nucleotidyltransferase poly(A) polymerase
HKOPHDEH_01840 3.03e-192 - - - - - - - -
HKOPHDEH_01841 1.48e-90 divK - - T - - - Response regulator receiver domain protein
HKOPHDEH_01844 0.0 - 3.2.1.37, 3.2.1.55 GH43,GH51 G ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HKOPHDEH_01845 0.0 - - - - - - - -
HKOPHDEH_01846 5.44e-177 ttcA - - H ko:K14058 - ko00000,ko03016 Belongs to the TtcA family
HKOPHDEH_01847 5.57e-83 - - - S ko:K09922 - ko00000 Psort location CytoplasmicMembrane, score
HKOPHDEH_01848 1.04e-246 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKOPHDEH_01849 1.52e-123 mntP - - P - - - Probably functions as a manganese efflux pump
HKOPHDEH_01850 5.95e-193 - - - S - - - COG NOG28307 non supervised orthologous group
HKOPHDEH_01851 6.05e-108 - - - S - - - COG NOG30522 non supervised orthologous group
HKOPHDEH_01852 2.98e-162 arnC - - M - - - involved in cell wall biogenesis
HKOPHDEH_01853 1.65e-211 nqrF 1.6.5.8 - C ko:K00351 - ko00000,ko01000 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway
HKOPHDEH_01854 1.58e-282 rmuC - - S ko:K09760 - ko00000 RmuC domain protein
HKOPHDEH_01855 1.16e-209 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Psort location Cytoplasmic, score
HKOPHDEH_01856 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
HKOPHDEH_01860 5.06e-129 rimN 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Belongs to the SUA5 family
HKOPHDEH_01861 8.62e-102 - - - S ko:K07107 - ko00000,ko01000 acyl-CoA thioester hydrolase, YbgC YbaW family
HKOPHDEH_01862 6.23e-288 - - - K ko:K02529 - ko00000,ko03000 transcriptional regulator (AraC family)
HKOPHDEH_01863 0.0 - - - S - - - PA14 domain protein
HKOPHDEH_01864 0.0 - - - M ko:K18139,ko:K18300 ko01501,ko02024,map01501,map02024 ko00000,ko00001,ko00002,ko01504,ko02000 Efflux transporter, outer membrane factor lipoprotein, NodT family
HKOPHDEH_01865 0.0 - - - V - - - Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKOPHDEH_01866 3.76e-244 - - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKOPHDEH_01868 1.14e-159 nqrC 1.6.5.8 - C ko:K00348 - ko00000,ko01000 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HKOPHDEH_01869 2.03e-272 nqrB 1.6.5.8 - C ko:K00347 - ko00000,ko01000 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HKOPHDEH_01870 0.0 nqrA 1.6.5.8 - C ko:K00346 - ko00000,ko01000 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HKOPHDEH_01871 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HKOPHDEH_01872 4.71e-23 - - - M - - - COG NOG26016 non supervised orthologous group
HKOPHDEH_01873 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01874 6.18e-275 - - - G - - - Alpha-1,2-mannosidase
HKOPHDEH_01875 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 9.97
HKOPHDEH_01876 3.56e-178 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKOPHDEH_01877 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
HKOPHDEH_01879 0.0 aglC 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 COG3345 Alpha-galactosidase
HKOPHDEH_01880 2.68e-111 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HKOPHDEH_01881 9.87e-125 - - - G - - - Glycosyl hydrolase family 63 C-terminal domain
HKOPHDEH_01882 9.05e-170 - 2.1.1.130, 2.1.1.151 - H ko:K03394 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 COG2243 Precorrin-2 methylase
HKOPHDEH_01883 8.25e-91 - - - S - - - Protein of unknown function (DUF1573)
HKOPHDEH_01884 0.0 - - - S - - - oligopeptide transporter, OPT family
HKOPHDEH_01885 1.43e-220 - - - I - - - pectin acetylesterase
HKOPHDEH_01886 1.59e-233 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 COG3250 Beta-galactosidase beta-glucuronidase
HKOPHDEH_01888 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKOPHDEH_01889 3.79e-62 - - - S - - - COG NOG23401 non supervised orthologous group
HKOPHDEH_01890 9.47e-304 lptD - - M - - - COG NOG06415 non supervised orthologous group
HKOPHDEH_01891 1.05e-285 surA 5.2.1.8 - M ko:K03771 - ko00000,ko01000,ko03110 peptidylprolyl isomerase
HKOPHDEH_01892 0.0 estA - - EV - - - beta-lactamase
HKOPHDEH_01893 1.11e-154 - 5.2.1.8 - M ko:K01802,ko:K03773 - ko00000,ko01000,ko03110 FkbP-type peptidyl-prolyl cis-trans
HKOPHDEH_01894 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
HKOPHDEH_01895 2.15e-286 bglB 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
HKOPHDEH_01896 8.91e-90 - 3.5.1.53 - S ko:K12251 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 hydrolase, carbon-nitrogen family
HKOPHDEH_01897 1.84e-83 - - - S - - - Psort location CytoplasmicMembrane, score 9.46
HKOPHDEH_01898 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKOPHDEH_01899 6.46e-243 - - - I - - - lipid kinase, YegS Rv2252 BmrU family
HKOPHDEH_01900 2.64e-287 - 2.3.1.47 - E ko:K00652 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Psort location Cytoplasmic, score
HKOPHDEH_01901 3.04e-87 loiP - - M ko:K07387 - ko00000,ko01000,ko01002 COG0501 Zn-dependent protease with chaperone function
HKOPHDEH_01902 2.27e-226 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKOPHDEH_01903 8.55e-17 - - - - - - - -
HKOPHDEH_01904 4.32e-200 - - - L - - - Helix-turn-helix domain
HKOPHDEH_01905 5.57e-270 - - - L - - - Belongs to the 'phage' integrase family
HKOPHDEH_01906 1.54e-187 - - - - - - - -
HKOPHDEH_01907 2.34e-85 - - - K - - - Helix-turn-helix domain
HKOPHDEH_01909 0.0 uvrA1 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKOPHDEH_01910 9.25e-291 - - - M ko:K03832 - ko00000,ko02000 Gram-negative bacterial TonB protein C-terminal
HKOPHDEH_01911 2.44e-67 - - - S ko:K07334 - ko00000,ko02048 Plasmid maintenance system killer protein
HKOPHDEH_01912 5.7e-63 higA - - K ko:K21498 - ko00000,ko02048 addiction module antidote protein, HigA
HKOPHDEH_01913 1.37e-92 - - - MU - - - COG NOG29365 non supervised orthologous group
HKOPHDEH_01914 1.23e-43 - - - S - - - COG NOG34202 non supervised orthologous group
HKOPHDEH_01915 3.14e-232 cstA - - T ko:K06200 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01917 0.0 - - - M - - - COG NOG06397 non supervised orthologous group
HKOPHDEH_01919 0.0 rnr - - J ko:K12573,ko:K12585 ko03018,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKOPHDEH_01920 1.08e-231 fieF - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKOPHDEH_01921 1.22e-248 - 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase dehydratase family
HKOPHDEH_01922 6.9e-232 - - - I - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01924 0.0 gltA 1.3.1.1, 1.4.1.13, 1.4.1.14 - C ko:K00266,ko:K17722 ko00240,ko00250,ko00410,ko00770,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00410,map00770,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 9.97
HKOPHDEH_01925 0.0 - - - H - - - Outer membrane protein beta-barrel family
HKOPHDEH_01926 7.51e-188 - - - E - - - GDSL-like Lipase/Acylhydrolase
HKOPHDEH_01927 1.4e-105 nodN - - I - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01928 9.38e-46 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01929 1.39e-75 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01930 1.46e-64 - - - S - - - COG NOG23408 non supervised orthologous group
HKOPHDEH_01931 7.82e-111 yvbK 2.3.1.82 - K ko:K18815 - br01600,ko00000,ko01000,ko01504 Psort location Cytoplasmic, score 8.96
HKOPHDEH_01935 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKOPHDEH_01936 2.62e-53 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKOPHDEH_01937 1.53e-199 mepM_1 - - M - - - Peptidase, M23
HKOPHDEH_01938 7.42e-125 - - - S - - - COG NOG27206 non supervised orthologous group
HKOPHDEH_01939 3.87e-300 doxX - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_01942 4.05e-250 - - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKOPHDEH_01943 3.44e-199 thiD 2.7.1.49, 2.7.4.7 - K ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 transcriptional regulator (AraC family)
HKOPHDEH_01946 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKOPHDEH_01947 1.24e-120 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKOPHDEH_01949 1.41e-211 - - - E - - - GDSL-like Lipase/Acylhydrolase
HKOPHDEH_01950 0.0 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase middle domain
HKOPHDEH_01951 6.46e-206 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKOPHDEH_01952 8.2e-310 dapL 2.6.1.83 - H ko:K10206 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate
HKOPHDEH_01953 9.07e-153 - - - S - - - Psort location OuterMembrane, score 9.52
HKOPHDEH_01954 6.12e-76 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
HKOPHDEH_01955 3.12e-311 amt - - P ko:K03320 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01957 3.22e-272 nanM - - S - - - COG NOG23382 non supervised orthologous group
HKOPHDEH_01958 2.85e-316 - - - S - - - COG NOG26034 non supervised orthologous group
HKOPHDEH_01959 3.95e-293 - - - I - - - COG NOG24984 non supervised orthologous group
HKOPHDEH_01960 1.24e-177 - - - K - - - COG3279 Response regulator of the LytR AlgR family
HKOPHDEH_01961 3.08e-84 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01962 0.0 - - - S - - - COG NOG26858 non supervised orthologous group
HKOPHDEH_01963 0.0 hppA 3.6.1.1 - C ko:K15987 ko00190,map00190 ko00000,ko00001,ko01000 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
HKOPHDEH_01968 1.57e-187 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_01969 1.4e-260 - - - G - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01970 6.96e-240 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_01972 1.51e-316 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HKOPHDEH_01973 5.6e-303 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan endo-1,4-beta-galactosidase
HKOPHDEH_01974 1.11e-239 cytR - - K ko:K02529,ko:K05499 - ko00000,ko03000 Psort location Cytoplasmic, score 9.97
HKOPHDEH_01975 0.0 - - - G ko:K16211 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_01976 1.48e-221 bglX 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 glycosyl hydrolase, family 3
HKOPHDEH_01977 0.0 - - - S - - - protein conserved in bacteria
HKOPHDEH_01978 0.0 - - - G - - - Belongs to the glycosyl hydrolase 43 family
HKOPHDEH_01979 6.5e-65 - - - S ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_01980 0.0 - - - G - - - Belongs to the glycosyl hydrolase 2 family
HKOPHDEH_01983 6.9e-198 - - - K - - - COG COG2207 AraC-type DNA-binding domain-containing proteins
HKOPHDEH_01984 3.19e-12 ykgB - - S - - - Psort location CytoplasmicMembrane, score 9.46
HKOPHDEH_01985 1.16e-88 ykgB - - S - - - Psort location CytoplasmicMembrane, score 9.46
HKOPHDEH_01986 4.59e-233 merA - - C ko:K21739 - ko00000 COG COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKOPHDEH_01987 3.22e-51 merA - - C ko:K21739 - ko00000 COG COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKOPHDEH_01988 1.85e-284 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HKOPHDEH_01989 1.69e-222 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKOPHDEH_01991 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_01992 2.08e-144 - - - K ko:K07735 - ko00000,ko03000 Belongs to the UPF0301 (AlgH) family
HKOPHDEH_01993 7.38e-127 speG 2.3.1.57 - J ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 Acetyltransferase, gnat family
HKOPHDEH_01994 0.0 - - - S - - - Fibrobacter succinogenes major domain (Fib_succ_major)
HKOPHDEH_01995 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKOPHDEH_01996 3.1e-138 folE 3.5.4.16 - F ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase I
HKOPHDEH_01998 2.46e-303 cbiE 2.1.1.132 - H ko:K00595 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE
HKOPHDEH_01999 0.0 cobJ 5.4.99.60, 5.4.99.61 - H ko:K06042 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 COG1010 Precorrin-3B methylase
HKOPHDEH_02000 2.19e-217 - - - K - - - transcriptional regulator (AraC family)
HKOPHDEH_02001 9.14e-152 cbiK 4.99.1.3 - H ko:K02190 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 CbiX
HKOPHDEH_02003 1.11e-152 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKOPHDEH_02004 1.02e-113 - 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKOPHDEH_02005 1.52e-201 - - - KT - - - MerR, DNA binding
HKOPHDEH_02006 2.65e-215 - - - S ko:K07017 - ko00000 Putative esterase
HKOPHDEH_02007 2.11e-98 - - - S - - - COG NOG14442 non supervised orthologous group
HKOPHDEH_02008 1.46e-152 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02009 1.77e-114 yfbT - - S - - - HAD hydrolase, family IA, variant 3
HKOPHDEH_02010 1.41e-125 - - - H - - - Susd and RagB outer membrane lipoprotein
HKOPHDEH_02011 1.03e-241 - - - G - - - Putative glycoside hydrolase Family 18, chitinase_18
HKOPHDEH_02012 9.04e-278 - - - S - - - Concanavalin A-like lectin/glucanases superfamily
HKOPHDEH_02013 0.0 - - - G - - - Psort location Extracellular, score
HKOPHDEH_02015 7.41e-315 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKOPHDEH_02016 3.05e-200 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_02017 4.96e-171 dacA - - S - - - Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKOPHDEH_02018 0.0 tldD1 - - S ko:K03568 - ko00000,ko01002 and their inactivated homologs
HKOPHDEH_02019 8.63e-59 - - - M - - - Glycosyltransferase Family 4
HKOPHDEH_02020 1.82e-280 - - - M - - - Psort location Cytoplasmic, score
HKOPHDEH_02021 1.17e-273 fcl 1.1.1.271 - GM ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
HKOPHDEH_02022 6.83e-175 - 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Belongs to the glycosyltransferase 26 family
HKOPHDEH_02023 1.3e-256 gmd 4.2.1.47 - M ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HKOPHDEH_02024 3.63e-138 acpH - - S - - - Acyl carrier protein phosphodiesterase
HKOPHDEH_02025 5.07e-158 lipB 2.3.1.181 - H ko:K03801 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate
HKOPHDEH_02026 4.52e-199 - - - K - - - COG2207 AraC-type DNA-binding domain-containing
HKOPHDEH_02027 0.0 copA 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02028 7.55e-59 - - - P ko:K08364 - ko00000,ko02000 Heavy metal-associated domain protein
HKOPHDEH_02029 8.71e-218 - - - P - - - COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
HKOPHDEH_02032 7.51e-212 - - - PT - - - Sigma factor regulatory protein, FecR PupR family
HKOPHDEH_02033 1.87e-133 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor
HKOPHDEH_02034 1.32e-117 - - - - - - - -
HKOPHDEH_02035 2.81e-52 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKOPHDEH_02036 9.13e-262 - - - S - - - COG NOG26558 non supervised orthologous group
HKOPHDEH_02037 6.23e-97 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02038 0.0 - - - G - - - SMP-30/Gluconolaconase/LRE-like region
HKOPHDEH_02039 4.91e-175 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HKOPHDEH_02040 1.19e-145 - - - C - - - Nitroreductase family
HKOPHDEH_02041 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HKOPHDEH_02042 4.82e-55 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKOPHDEH_02043 4e-202 - - - KT - - - Transcriptional regulatory protein, C terminal
HKOPHDEH_02044 6.55e-65 - - - T - - - COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HKOPHDEH_02046 2.34e-75 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02047 7.79e-220 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02048 2.52e-114 - - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog
HKOPHDEH_02049 1.21e-119 - - - O - - - Dual-action HEIGH metallo-peptidase
HKOPHDEH_02050 4.22e-183 - - - G - - - Psort location Extracellular, score
HKOPHDEH_02052 3.5e-234 - - - G - - - Repeats in polycystic kidney disease 1 (PKD1) and other proteins
HKOPHDEH_02053 1.9e-26 - - - S ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_02054 6.43e-148 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKOPHDEH_02055 5.61e-293 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 COG1760 L-serine deaminase
HKOPHDEH_02056 4.23e-120 - - - S - - - COG NOG31242 non supervised orthologous group
HKOPHDEH_02057 1.32e-97 - - - S - - - COG NOG31508 non supervised orthologous group
HKOPHDEH_02058 9.19e-303 qseC - - T - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_02059 2.8e-117 - - - K - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKOPHDEH_02060 1.7e-141 - - - L - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02061 1.97e-34 - - - - - - - -
HKOPHDEH_02062 0.0 - - - N - - - COG NOG14601 non supervised orthologous group
HKOPHDEH_02063 3.42e-28 aviRb - - J ko:K03437 - ko00000,ko03016 RNA methyltransferase, TrmH
HKOPHDEH_02064 2.77e-80 - - - - - - - -
HKOPHDEH_02065 2.12e-224 - - - S - - - COG NOG25370 non supervised orthologous group
HKOPHDEH_02066 5.74e-155 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKOPHDEH_02067 5.93e-80 yocK - - T - - - RNA polymerase-binding protein DksA
HKOPHDEH_02068 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKOPHDEH_02069 8.05e-166 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 Succinate dehydrogenase cytochrome B subunit, b558 family
HKOPHDEH_02070 1.24e-202 - - - K - - - transcriptional regulator (AraC family)
HKOPHDEH_02071 4.36e-136 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Psort location CytoplasmicMembrane, score
HKOPHDEH_02072 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HKOPHDEH_02073 6.68e-103 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKOPHDEH_02074 1.42e-214 - - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKOPHDEH_02075 4.26e-169 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKOPHDEH_02076 3.17e-280 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
HKOPHDEH_02077 7.17e-258 cheA - - T - - - two-component sensor histidine kinase
HKOPHDEH_02079 2.37e-112 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HKOPHDEH_02080 1.68e-179 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
HKOPHDEH_02081 1.1e-129 - - - M ko:K06142 - ko00000 membrane
HKOPHDEH_02082 2.46e-43 - - - S - - - COG NOG35566 non supervised orthologous group
HKOPHDEH_02083 0.0 pepD_1 - - E ko:K01270 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Psort location Cytoplasmic, score 8.96
HKOPHDEH_02084 1.15e-70 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HKOPHDEH_02085 1.2e-283 thiH 4.1.99.19 - C ko:K03150 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiazole biosynthesis protein ThiH
HKOPHDEH_02086 4.49e-167 moeZ 2.7.7.80, 2.8.1.11 - H ko:K21029,ko:K21147 ko04122,map04122 ko00000,ko00001,ko01000 involved in molybdopterin and thiamine biosynthesis family 2
HKOPHDEH_02087 1.47e-143 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Thiamine monophosphate synthase TENI
HKOPHDEH_02088 1.82e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 COG0351 Hydroxymethylpyrimidine phosphomethylpyrimidine kinase
HKOPHDEH_02089 2.91e-146 - - - J - - - Domain of unknown function (DUF4476)
HKOPHDEH_02091 1.97e-137 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKOPHDEH_02092 1.29e-246 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKOPHDEH_02093 1.64e-108 - - - G - - - Cupin 2, conserved barrel domain protein
HKOPHDEH_02094 2.08e-77 - - - K - - - Transcription termination antitermination factor NusG
HKOPHDEH_02095 5.45e-160 - - - M - - - Chain length determinant protein
HKOPHDEH_02096 2.44e-166 - - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
HKOPHDEH_02097 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_02098 5.15e-100 hsp20 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HKOPHDEH_02099 5.46e-108 - - - J - - - Threonine alanine tRNA ligase second additional domain protein
HKOPHDEH_02100 0.0 - - - J - - - Psort location Cytoplasmic, score
HKOPHDEH_02101 0.0 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02104 3.87e-305 - 3.2.1.180 GH88 M ko:K18581 - ko00000,ko01000 Glycosyl Hydrolase Family 88
HKOPHDEH_02106 1.44e-24 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02107 9.74e-52 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02108 1.05e-120 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02109 5.34e-178 - - - G - - - Belongs to the glycosyl hydrolase 28 family
HKOPHDEH_02110 1.38e-98 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_02111 0.0 - 3.2.1.25 - G ko:K01192 ko00511,ko04142,map00511,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 2, sugar binding domain protein
HKOPHDEH_02112 1.17e-264 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_02120 3.81e-144 acm - - M ko:K07273 - ko00000 phage tail component domain protein
HKOPHDEH_02121 9.37e-294 - - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system permease component
HKOPHDEH_02122 8.2e-287 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HKOPHDEH_02123 4.88e-200 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
HKOPHDEH_02124 1.07e-160 - - - P - - - Psort location Cytoplasmic, score
HKOPHDEH_02125 2.95e-146 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HKOPHDEH_02126 5.1e-206 - - - S - - - Protein of unknown function (DUF3298)
HKOPHDEH_02127 2.1e-79 - - - - - - - -
HKOPHDEH_02129 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
HKOPHDEH_02131 3.66e-17 - - - S - - - Phage minor structural protein
HKOPHDEH_02135 2.35e-56 - - - L - - - COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
HKOPHDEH_02136 3.37e-118 - - - L - - - COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
HKOPHDEH_02137 2.36e-141 - - - S - - - Zeta toxin
HKOPHDEH_02138 7.06e-130 - - - S - - - ATP cob(I)alamin adenosyltransferase
HKOPHDEH_02139 7.09e-296 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKOPHDEH_02140 0.0 - - - V ko:K01992 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02141 0.0 - - - H ko:K02014 - ko00000,ko02000 COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
HKOPHDEH_02142 0.0 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02143 9.76e-238 ravA_1 - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
HKOPHDEH_02146 0.0 dnaX 2.7.7.7 - H ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKOPHDEH_02147 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_02148 3.13e-171 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02149 0.0 - - - S - - - Tat pathway signal sequence domain protein
HKOPHDEH_02150 1.49e-195 - - - G - - - COG NOG16664 non supervised orthologous group
HKOPHDEH_02151 2.11e-220 - - - M - - - COG COG1082 Sugar phosphate isomerases epimerases
HKOPHDEH_02152 5.3e-79 rnhA 3.1.26.4 - C ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 double-stranded RNA RNA-DNA hybrid binding protein
HKOPHDEH_02153 1.28e-118 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02154 1.03e-236 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HKOPHDEH_02155 0.0 exuT - - G ko:K08191 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02156 1e-249 - 3.6.4.12 - L ko:K10742 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG COG1112 Superfamily I DNA and RNA helicases and helicase subunits
HKOPHDEH_02157 7.61e-218 oxyR - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 Psort location Cytoplasmic, score 9.97
HKOPHDEH_02158 2.47e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Psort location Cytoplasmic, score
HKOPHDEH_02159 0.0 ahpF - - C ko:K03387 - ko00000,ko01000 alkyl hydroperoxide reductase subunit F
HKOPHDEH_02160 1.05e-234 - - - E - - - COG NOG04781 non supervised orthologous group
HKOPHDEH_02161 1.17e-79 - - - S - - - COG NOG23405 non supervised orthologous group
HKOPHDEH_02162 1.49e-126 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HKOPHDEH_02163 6.06e-222 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKOPHDEH_02164 2.12e-179 - - - - - - - -
HKOPHDEH_02165 0.0 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
HKOPHDEH_02166 1.92e-38 - - - - - - - -
HKOPHDEH_02168 1.33e-161 smtA 2.1.1.223 - J ko:K15460 - ko00000,ko01000,ko03016 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HKOPHDEH_02170 7.79e-213 zraS_1 - - T - - - GHKL domain
HKOPHDEH_02171 2.08e-123 - - - T - - - Sigma-54 interaction domain protein
HKOPHDEH_02172 0.0 - - - G - - - Belongs to the glycosyl hydrolase 43 family
HKOPHDEH_02173 7.82e-194 - - - S - - - Phospholipase/Carboxylesterase
HKOPHDEH_02174 1.88e-251 - - - S - - - Calcineurin-like phosphoesterase
HKOPHDEH_02175 1.76e-205 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HKOPHDEH_02176 9.25e-69 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HKOPHDEH_02178 7.68e-274 - - - O - - - COG NOG14454 non supervised orthologous group
HKOPHDEH_02179 2.04e-95 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKOPHDEH_02180 7.99e-89 hinT - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family
HKOPHDEH_02181 2.43e-224 manC 2.7.7.13 - M ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 ko00000,ko00001,ko00002,ko01000 mannose-1-phosphate guanylyltransferase
HKOPHDEH_02182 1.22e-74 - - - C - - - COG NOG19100 non supervised orthologous group
HKOPHDEH_02183 3.57e-76 mmdC - - I - - - first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKOPHDEH_02184 8.53e-268 oadB 4.1.1.3 - C ko:K01572 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 sodium ion-translocating decarboxylase, beta subunit
HKOPHDEH_02185 0.0 - - - S - - - Tetratricopeptide repeat protein
HKOPHDEH_02188 0.0 - 3.2.1.31 - M ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 2, sugar binding domain protein
HKOPHDEH_02189 0.0 - 3.2.1.20 GH31 M ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG NOG06228 non supervised orthologous group
HKOPHDEH_02190 5.95e-292 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKOPHDEH_02191 6.77e-305 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HKOPHDEH_02192 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKOPHDEH_02193 1.58e-47 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKOPHDEH_02194 1.47e-105 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKOPHDEH_02195 1.07e-303 waaA 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 M ko:K02527 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Psort location Cytoplasmic, score 8.96
HKOPHDEH_02196 1.95e-97 dapH - - S - - - Bacterial transferase hexapeptide repeat protein
HKOPHDEH_02197 0.0 - 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HKOPHDEH_02198 3.6e-287 - 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Carboxyl transferase domain
HKOPHDEH_02199 0.0 - - - P ko:K07085 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02200 2.51e-185 hddC - - JM - - - COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)
HKOPHDEH_02201 3.47e-90 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02202 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HKOPHDEH_02204 8.81e-286 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKOPHDEH_02205 1.96e-108 ftnA 1.16.3.2 - P ko:K02217 - ko00000,ko01000 Iron-storage protein
HKOPHDEH_02206 2.87e-167 kbl 2.3.1.29 - H ko:K00639 ko00260,map00260 ko00000,ko00001,ko01000,ko01007 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA
HKOPHDEH_02207 7.12e-280 - - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system permease component
HKOPHDEH_02208 4.31e-278 - - - M ko:K02005 - ko00000 Efflux transporter, RND family, MFP subunit
HKOPHDEH_02209 1.88e-222 lytG - - MNU - - - COG1705 Muramidase (flagellum-specific)
HKOPHDEH_02210 4.47e-160 ydjH_1 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family
HKOPHDEH_02211 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_02212 2.98e-37 - - - - - - - -
HKOPHDEH_02213 9.6e-98 nifJ 1.2.7.1 - C ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HKOPHDEH_02215 1.72e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HKOPHDEH_02216 3e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 50S ribosomal protein L30
HKOPHDEH_02217 3.17e-113 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKOPHDEH_02218 2.09e-72 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKOPHDEH_02219 2.88e-131 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKOPHDEH_02220 2.47e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKOPHDEH_02221 9.52e-62 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKOPHDEH_02222 1.73e-121 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKOPHDEH_02225 8.59e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKOPHDEH_02226 0.0 - - - S - - - P-loop ATPase and inactivated derivatives
HKOPHDEH_02227 2.83e-109 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKOPHDEH_02228 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKOPHDEH_02230 0.0 - - - S ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_02231 1.24e-243 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_02232 2.76e-292 - - - S ko:K07133 - ko00000 ATPase (AAA superfamily)
HKOPHDEH_02233 9.19e-224 nifJ 1.2.7.1 - C ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HKOPHDEH_02236 0.0 - - - S - - - Psort location OuterMembrane, score 9.49
HKOPHDEH_02237 9.55e-260 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HKOPHDEH_02238 1.4e-129 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_02239 1.11e-299 nhaA - - P ko:K03313 - ko00000,ko02000 ) H( ) antiporter that extrudes sodium in exchange for external protons
HKOPHDEH_02240 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKOPHDEH_02241 2.09e-41 - - - S - - - COG NOG33517 non supervised orthologous group
HKOPHDEH_02242 0.0 wbpM - - GM - - - Polysaccharide biosynthesis protein
HKOPHDEH_02243 2.22e-230 preA 1.3.98.1 - F ko:K00226 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
HKOPHDEH_02244 5.06e-159 yggS - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKOPHDEH_02245 8.08e-105 - - - S - - - COG NOG14445 non supervised orthologous group
HKOPHDEH_02246 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)
HKOPHDEH_02247 2.5e-99 - - - S - - - COG NOG29214 non supervised orthologous group
HKOPHDEH_02248 0.0 - - - E - - - Peptidase family M1 domain
HKOPHDEH_02249 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKOPHDEH_02251 7.31e-218 prs 2.7.6.1 - EF ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG0462 Phosphoribosylpyrophosphate synthetase
HKOPHDEH_02256 1.03e-167 - - - G - - - beta-galactosidase activity
HKOPHDEH_02257 1.92e-289 - - - T - - - Y_Y_Y domain
HKOPHDEH_02258 2.48e-124 - - - K ko:K03088 - ko00000,ko03021 Sigma-70, region 4
HKOPHDEH_02259 2.03e-309 - - - S - - - Outer membrane protein beta-barrel domain
HKOPHDEH_02261 2.34e-98 ktrB - - P ko:K03498 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02262 5.02e-158 ktrA - - C ko:K03499 - ko00000,ko02000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_02263 0.0 - - - S - - - Protein of unknown function (DUF3843)
HKOPHDEH_02264 5.96e-146 - - - L - - - COG NOG29822 non supervised orthologous group
HKOPHDEH_02266 1.96e-217 uxaB 1.1.1.17, 1.1.1.58 - C ko:K00009,ko:K00041 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the mannitol dehydrogenase family. UxaB subfamily
HKOPHDEH_02267 3.42e-124 - - - T - - - FHA domain protein
HKOPHDEH_02268 1.72e-266 - - - S - - - Sporulation and cell division repeat protein
HKOPHDEH_02271 1.21e-202 - - - S ko:K07037 - ko00000 7TM receptor with intracellular HD hydrolase
HKOPHDEH_02272 1.32e-182 - - - S ko:K07037 - ko00000 7TM receptor with intracellular HD hydrolase
HKOPHDEH_02273 1.19e-184 - - - - - - - -
HKOPHDEH_02274 2.34e-205 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKOPHDEH_02275 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKOPHDEH_02276 1.7e-179 pgl 3.1.1.31 - G ko:K01057 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase
HKOPHDEH_02277 3.89e-242 yhiM - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02278 2.66e-211 potA 3.6.3.29, 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K02017,ko:K10112,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKOPHDEH_02279 7.99e-183 - - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02280 1.6e-176 ydcV - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
HKOPHDEH_02281 0.0 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Psort location Periplasmic, score 9.44
HKOPHDEH_02282 1.43e-170 rnfB - - C ko:K03616 - ko00000 electron transport complex, RnfABCDGE type, B subunit
HKOPHDEH_02283 1.45e-93 - - - T ko:K03803 - ko00000,ko03021 Positive regulator of sigma(E), RseC MucC
HKOPHDEH_02284 0.0 - - - S - - - Protein of unknown function (DUF3078)
HKOPHDEH_02286 3.35e-184 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
HKOPHDEH_02287 2.46e-242 - - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
HKOPHDEH_02289 1.06e-162 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HKOPHDEH_02290 2.35e-214 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKOPHDEH_02291 1.02e-190 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HKOPHDEH_02292 2.61e-105 - - - K - - - COG NOG19093 non supervised orthologous group
HKOPHDEH_02295 9.07e-150 - - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
HKOPHDEH_02296 3.04e-148 - - - S ko:K03975 - ko00000 Psort location CytoplasmicMembrane, score
HKOPHDEH_02297 2.17e-96 - - - - - - - -
HKOPHDEH_02302 4.34e-46 - - - S - - - PFAM Uncharacterised protein family UPF0150
HKOPHDEH_02304 2.92e-30 - - - - - - - -
HKOPHDEH_02306 1.9e-30 - - - - - - - -
HKOPHDEH_02310 2.11e-84 - - - - - - - -
HKOPHDEH_02311 3.16e-86 - - - V - - - MATE efflux family protein
HKOPHDEH_02312 0.0 pop - - EU - - - Peptidase, S9A B C family, catalytic domain protein
HKOPHDEH_02313 5.94e-263 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKOPHDEH_02314 0.0 dapE - - E - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02316 0.0 - - - S ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_02317 0.0 - - - - - - - -
HKOPHDEH_02318 9.62e-143 - - - JM - - - COG NOG09722 non supervised orthologous group
HKOPHDEH_02319 7.12e-310 - - - V - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02320 1.49e-215 - - - S - - - Uncharacterised nucleotidyltransferase
HKOPHDEH_02321 4.4e-28 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
HKOPHDEH_02323 1.42e-34 - - - - - - - -
HKOPHDEH_02325 0.0 - - - G - - - Fibronectin type III
HKOPHDEH_02326 5.14e-219 - - - E ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_02330 4.88e-195 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKOPHDEH_02331 3.07e-298 fprA 1.6.3.4 - C ko:K22405 - ko00000,ko01000 anaerobic nitric oxide reductase flavorubredoxin
HKOPHDEH_02332 0.0 - - - S - - - COG NOG25960 non supervised orthologous group
HKOPHDEH_02333 3.64e-97 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_02334 7.45e-150 pgsA1 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKOPHDEH_02335 2.21e-227 - - - I - - - Inositolphosphotransferase 1, involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), which is the most abundant sphingolipid in cells, mutation confers resistance to the antifungals syringomycin E and DmAMP1 in some growth media
HKOPHDEH_02336 2.96e-286 - - - C ko:K19955 - ko00000,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_02337 4.75e-134 rng - - J ko:K08301 - ko00000,ko01000,ko03009,ko03019 S1 RNA binding domain
HKOPHDEH_02338 3.65e-279 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
HKOPHDEH_02339 2.08e-172 - - - S - - - Pfam:DUF1498
HKOPHDEH_02340 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR Asp-box repeat protein
HKOPHDEH_02341 4.11e-308 - - - C ko:K18930 - ko00000 FAD binding domain
HKOPHDEH_02342 2.69e-277 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02343 6.69e-202 - - - G - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02345 1.2e-218 - 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
HKOPHDEH_02346 1.91e-292 - 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65 central catalytic domain
HKOPHDEH_02347 5.98e-243 - - - M - - - Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKOPHDEH_02349 2.75e-294 ampG - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02350 0.0 - - - G - - - Alpha-1,2-mannosidase
HKOPHDEH_02351 3.67e-163 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG COG0120 Ribose 5-phosphate isomerase
HKOPHDEH_02352 0.0 ydaH - - H ko:K12942 - ko00000 Psort location CytoplasmicMembrane, score
HKOPHDEH_02353 1.28e-167 - - - T - - - Response regulator receiver domain
HKOPHDEH_02354 5.76e-171 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_02356 3.31e-239 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 COG1466 DNA polymerase III, delta subunit
HKOPHDEH_02357 8.08e-188 amn 3.2.2.4 - F ko:K01241 ko00230,map00230 ko00000,ko00001,ko01000 COG COG0775 Nucleoside phosphorylase
HKOPHDEH_02358 7.87e-105 - - - V - - - COG NOG14438 non supervised orthologous group
HKOPHDEH_02359 1.35e-205 per1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 COG2367 Beta-lactamase class A
HKOPHDEH_02360 0.0 - - - KT - - - COG NOG11230 non supervised orthologous group
HKOPHDEH_02363 0.0 msbA - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HKOPHDEH_02365 1.44e-180 - - - CO - - - AhpC TSA family
HKOPHDEH_02366 0.0 - - - KT - - - COG NOG25147 non supervised orthologous group
HKOPHDEH_02367 2.11e-97 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HKOPHDEH_02368 8.74e-55 - - - S - - - Psort location CytoplasmicMembrane, score 9.46
HKOPHDEH_02369 1.22e-142 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02370 2.27e-94 mip 5.2.1.8 - O ko:K01802 - ko00000,ko01000 COG COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1
HKOPHDEH_02371 5.25e-37 - - - - - - - -
HKOPHDEH_02372 8.62e-117 - - - T - - - Tetratricopeptide repeat protein
HKOPHDEH_02373 8.03e-179 - - - T ko:K02477 - ko00000,ko02022 COG3279 Response regulator of the LytR AlgR family
HKOPHDEH_02374 2.32e-75 - - - S - - - COG NOG30654 non supervised orthologous group
HKOPHDEH_02375 5.5e-286 - - - S - - - COG NOG27441 non supervised orthologous group
HKOPHDEH_02377 2.64e-97 - - - S ko:K15977 - ko00000 Psort location CytoplasmicMembrane, score 9.46
HKOPHDEH_02378 1.36e-315 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase, FAD-containing subunit
HKOPHDEH_02379 1.18e-299 - - - M - - - COG NOG06295 non supervised orthologous group
HKOPHDEH_02381 2.15e-132 - - - C ko:K02120 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Psort location Cytoplasmic, score 8.96
HKOPHDEH_02382 0.0 ntpB - - C ko:K02118 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 ATP synthase alpha beta family, nucleotide-binding domain protein
HKOPHDEH_02383 5.72e-312 atpA 3.6.3.14, 3.6.3.15 - C ko:K02117 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
HKOPHDEH_02384 3.93e-228 - - - O - - - Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HKOPHDEH_02387 7.13e-113 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HKOPHDEH_02388 2.81e-247 - - - S ko:K09955 - ko00000 Beta-L-arabinofuranosidase, GH127
HKOPHDEH_02389 0.0 - - - S - - - domain protein
HKOPHDEH_02390 0.0 - - - P ko:K16089 - ko00000,ko02000 COG4771 Outer membrane receptor for ferrienterochelin and colicins
HKOPHDEH_02391 0.0 - - - P - - - Psort location OuterMembrane, score
HKOPHDEH_02392 5.5e-165 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKOPHDEH_02393 9.26e-270 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKOPHDEH_02394 2.07e-238 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HKOPHDEH_02395 1.09e-101 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate synthase
HKOPHDEH_02397 1.63e-297 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02398 1.34e-108 cyaA 4.6.1.1 - S ko:K01768 ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_02399 1.14e-09 - - - - - - - -
HKOPHDEH_02400 2.17e-226 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKOPHDEH_02401 3.29e-179 - - - PT - - - Sigma factor regulatory protein, FecR PupR family
HKOPHDEH_02402 1.17e-259 - - - G - - - Alpha-1,2-mannosidase
HKOPHDEH_02403 1.35e-133 - - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog
HKOPHDEH_02404 6.34e-233 - - - PT - - - Sigma factor regulatory protein, FecR PupR family
HKOPHDEH_02408 0.0 dinF - - V ko:K03327 - ko00000,ko02000 MATE efflux family protein
HKOPHDEH_02409 2.18e-153 - - - S - - - COG NOG28155 non supervised orthologous group
HKOPHDEH_02410 1.54e-164 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_02411 3.42e-249 - 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Glycosyl hydrolase family 26
HKOPHDEH_02414 1.03e-09 - - - - - - - -
HKOPHDEH_02415 2.65e-81 - - - K - - - Bacterial regulatory proteins, gntR family
HKOPHDEH_02416 7.14e-185 - - - - - - - -
HKOPHDEH_02417 5.62e-187 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HKOPHDEH_02418 6.63e-121 hly-III - - S ko:K11068 - ko00000,ko02042 membrane protein, hemolysin III homolog
HKOPHDEH_02419 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Psort location Cytoplasmic, score
HKOPHDEH_02420 6.45e-91 - - - S - - - Polyketide cyclase
HKOPHDEH_02421 5.07e-150 pyrE 2.4.2.10, 4.1.1.23 - F ko:K00762,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKOPHDEH_02422 3.14e-109 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
HKOPHDEH_02423 7.23e-112 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKOPHDEH_02424 0.0 kpsD - - M - - - COG1596 Periplasmic protein involved in polysaccharide export
HKOPHDEH_02425 3.23e-189 wbpM - - GM - - - Polysaccharide biosynthesis protein
HKOPHDEH_02427 5.86e-297 - - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase
HKOPHDEH_02428 6.32e-259 - - - P ko:K07214 - ko00000 Putative esterase
HKOPHDEH_02429 3.81e-310 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1271 Cytochrome bd-type quinol oxidase, subunit 1
HKOPHDEH_02430 2.7e-278 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase subunit 2
HKOPHDEH_02431 5.22e-163 mtgA 2.4.1.129 GT51 M ko:K03814 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HKOPHDEH_02432 1.24e-95 - - - M - - - COG2885 Outer membrane protein and related peptidoglycan-associated
HKOPHDEH_02433 8.71e-227 yhgF - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain
HKOPHDEH_02434 7.03e-193 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family
HKOPHDEH_02435 7.39e-253 - - - S - - - COG NOG26673 non supervised orthologous group
HKOPHDEH_02436 4.74e-73 - - - S - - - COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKOPHDEH_02437 1.44e-28 - - - F ko:K21572 - ko00000,ko02000 COG NOG30008 non supervised orthologous group
HKOPHDEH_02438 1.69e-170 - - - S - - - Protein of unknown function (DUF3823)
HKOPHDEH_02442 3.91e-184 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HKOPHDEH_02443 3.78e-267 gcvT 2.1.2.10 - H ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
HKOPHDEH_02444 0.0 - - - S - - - Peptidase family M48
HKOPHDEH_02445 2.14e-77 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKOPHDEH_02446 4.92e-149 fahA - - Q - - - 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase, fumarylacetoacetate hydrolase family K01828
HKOPHDEH_02447 5.04e-244 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02449 1.08e-45 - - - IQ - - - Oxidoreductase, short chain dehydrogenase reductase family protein
HKOPHDEH_02450 1.45e-231 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKOPHDEH_02451 2.42e-181 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HKOPHDEH_02452 4.13e-189 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HKOPHDEH_02453 0.0 - - - S - - - P-loop ATPase and inactivated derivatives
HKOPHDEH_02454 8.64e-41 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02455 2.88e-24 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02456 3.6e-241 mltD_2 - - M - - - Transglycosylase SLT domain protein
HKOPHDEH_02457 1.23e-169 - - - S - - - Oxidoreductase, short chain dehydrogenase reductase family protein
HKOPHDEH_02458 3.46e-95 yjbQ - - S - - - Secondary thiamine-phosphate synthase enzyme
HKOPHDEH_02459 1.98e-204 - - - T - - - Psort location CytoplasmicMembrane, score 7.88
HKOPHDEH_02460 5.31e-242 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
HKOPHDEH_02461 7.07e-103 - - - EG - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02462 1.1e-41 - - - EG - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02463 7.44e-206 - - - K ko:K13652 - ko00000,ko03000 methylphosphotriester-DNA alkyltransferase (AraC XylS family)
HKOPHDEH_02466 1.81e-128 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKOPHDEH_02467 1.59e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKOPHDEH_02468 3.35e-33 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKOPHDEH_02469 8.31e-253 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HKOPHDEH_02470 1.02e-93 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_02471 2.12e-53 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 ATP synthase, delta epsilon subunit, beta-sandwich domain protein
HKOPHDEH_02472 3.94e-68 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKOPHDEH_02473 1.99e-263 - - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKOPHDEH_02474 2.9e-224 - - - K - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02475 1.55e-265 dacB 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
HKOPHDEH_02477 0.0 - - - V - - - beta-lactamase
HKOPHDEH_02478 9.38e-300 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 COG NOG04001 non supervised orthologous group
HKOPHDEH_02479 5.59e-204 - - - O - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_02480 1.17e-52 batA - - S ko:K07114 - ko00000,ko02000 Von Willebrand factor type A domain
HKOPHDEH_02482 1.63e-236 batB - - S ko:K07114 - ko00000,ko02000 Von Willebrand factor type A domain
HKOPHDEH_02483 4.04e-44 - - - V - - - ABC transporter, permease protein
HKOPHDEH_02484 5.83e-308 - - - V - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02485 1.03e-155 pgmB - - S - - - HAD hydrolase, family IA, variant 3
HKOPHDEH_02486 3.03e-190 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HKOPHDEH_02488 2.03e-297 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HKOPHDEH_02489 6.47e-149 - - - S ko:K07052 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02490 1.58e-64 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02491 5.91e-135 - - - L - - - COG NOG25561 non supervised orthologous group
HKOPHDEH_02492 6.11e-48 - - - S - - - Domain of unknown function (DUF4248)
HKOPHDEH_02493 1.13e-103 - - - L - - - regulation of translation
HKOPHDEH_02494 6.24e-107 - 3.5.1.28 - V ko:K01447 - ko00000,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_02495 3.69e-147 - - - S - - - GlcNAc-PI de-N-acetylase
HKOPHDEH_02496 2.26e-76 neuB 2.5.1.101, 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898,ko:K18430 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 PFAM N-acetylneuraminic acid synthase
HKOPHDEH_02497 6.51e-105 - - - G - - - Kinase, PfkB family
HKOPHDEH_02498 0.0 prc 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HKOPHDEH_02499 6.65e-194 - - - S - - - Predicted AAA-ATPase
HKOPHDEH_02500 9.97e-27 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02501 6.09e-152 - - - S - - - AAA domain, putative AbiEii toxin, Type IV TA system
HKOPHDEH_02502 2.18e-110 - 3.5.1.28 - V ko:K01447 - ko00000,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_02503 5.67e-180 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKOPHDEH_02504 1.43e-154 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HKOPHDEH_02505 1.21e-142 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 COG0307 Riboflavin synthase alpha chain
HKOPHDEH_02506 1.75e-07 - - - C - - - Nitroreductase family
HKOPHDEH_02507 6.4e-160 yihY - - S ko:K07058 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02508 5.55e-207 - - - S - - - COG NOG32009 non supervised orthologous group
HKOPHDEH_02509 5.93e-303 - - - - - - - -
HKOPHDEH_02511 1.09e-224 - - - S - - - COG NOG31846 non supervised orthologous group
HKOPHDEH_02512 8.18e-243 - - - S - - - COG NOG26135 non supervised orthologous group
HKOPHDEH_02513 4.55e-155 - - - M - - - COG NOG24980 non supervised orthologous group
HKOPHDEH_02514 0.0 - - - - - - - -
HKOPHDEH_02515 5.09e-120 - - - S ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_02517 8.32e-122 leuA_1 2.3.1.182 - E ko:K09011 ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the alpha-IPM synthase homocitrate synthase family
HKOPHDEH_02518 8.2e-145 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKOPHDEH_02519 1.25e-78 leuC 4.2.1.33, 4.2.1.35 - H ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKOPHDEH_02520 1.39e-241 leuC 4.2.1.33, 4.2.1.35 - H ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKOPHDEH_02521 1.32e-87 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HKOPHDEH_02522 1.53e-71 - - - S - - - COG NOG27987 non supervised orthologous group
HKOPHDEH_02523 0.0 mutS_2 - - L - - - DNA mismatch repair protein MutS
HKOPHDEH_02524 6.65e-169 - - - S - - - COG NOG29571 non supervised orthologous group
HKOPHDEH_02526 6.91e-219 corA - - P ko:K03284 - ko00000,ko02000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_02527 4.38e-146 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKOPHDEH_02529 3.08e-70 - - - - - - - -
HKOPHDEH_02530 0.0 - - - U - - - WD40-like Beta Propeller Repeat
HKOPHDEH_02532 2.3e-135 tabA_1 - - G - - - COG COG2731 Beta-galactosidase, beta subunit
HKOPHDEH_02533 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
HKOPHDEH_02534 8.31e-12 - - - - - - - -
HKOPHDEH_02535 3.98e-101 - - - L - - - Bacterial DNA-binding protein
HKOPHDEH_02536 1.36e-123 mrcA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 COG5009 Membrane carboxypeptidase penicillin-binding protein
HKOPHDEH_02537 2.88e-80 folK2 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 COG NOG22185 non supervised orthologous group
HKOPHDEH_02538 1.62e-179 kdsB 2.7.7.38 - H ko:K00979 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HKOPHDEH_02539 1.09e-310 - - - S - - - Peptidase M16 inactive domain
HKOPHDEH_02542 0.0 - - - M - - - Belongs to the glycosyl hydrolase 28 family
HKOPHDEH_02543 1.29e-233 - - - S - - - COG NOG26583 non supervised orthologous group
HKOPHDEH_02544 1.37e-273 - - - S - - - COG NOG10884 non supervised orthologous group
HKOPHDEH_02545 1.32e-258 cysN 2.7.1.25, 2.7.7.4 - H ko:K00955,ko:K00956 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
HKOPHDEH_02546 3.85e-103 - - - S - - - COG NOG16874 non supervised orthologous group
HKOPHDEH_02547 2.43e-190 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Psort location Cytoplasmic, score 9.97
HKOPHDEH_02548 8.55e-288 mntH - - P ko:K03322 - ko00000,ko02000 Metal ion transporter, metal ion (Mn2 Fe2 ) transporter (Nramp) family
HKOPHDEH_02549 1.91e-55 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02550 5.27e-102 yebC - - K - - - Transcriptional regulatory protein
HKOPHDEH_02551 2.93e-298 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Psort location Cytoplasmic, score
HKOPHDEH_02552 3.84e-160 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKOPHDEH_02553 7.68e-113 - - - EGP - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02555 7.94e-279 fucP - - G ko:K02429 - ko00000,ko02000 L-fucose H symporter permease
HKOPHDEH_02556 1.4e-117 - - - P ko:K07240 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
HKOPHDEH_02557 6.39e-121 - - - P ko:K07240 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
HKOPHDEH_02559 4.53e-45 - - - - - - - -
HKOPHDEH_02560 2.37e-242 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKOPHDEH_02561 1.64e-205 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKOPHDEH_02563 4.54e-247 - - - M ko:K02022 - ko00000 HlyD family secretion protein
HKOPHDEH_02564 1.51e-186 lpxA2 2.3.1.129 - M ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 ko00000,ko00001,ko00002,ko01000,ko01005 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HKOPHDEH_02565 2.49e-205 - - - MU - - - Efflux transporter, outer membrane factor lipoprotein, NodT family
HKOPHDEH_02566 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit
HKOPHDEH_02567 3.71e-185 frdB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG0479 Succinate dehydrogenase fumarate reductase Fe-S protein subunit
HKOPHDEH_02568 4.24e-170 - - - K - - - Transcriptional regulator, AraC family
HKOPHDEH_02569 1.05e-212 - - - M ko:K21572 - ko00000,ko02000 SusD family
HKOPHDEH_02570 1.05e-259 - - - P - - - TonB dependent receptor
HKOPHDEH_02571 1.26e-158 - - - S - - - Tetratricopeptide repeat protein
HKOPHDEH_02572 2.42e-126 - - - S - - - COG NOG29315 non supervised orthologous group
HKOPHDEH_02573 1.84e-242 envC - - D - - - Peptidase, M23
HKOPHDEH_02574 1.97e-145 argE 3.5.1.16 - E ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related
HKOPHDEH_02575 8.39e-283 - - - G - - - Glyco_18
HKOPHDEH_02576 1.03e-307 - - - S - - - COG NOG10142 non supervised orthologous group
HKOPHDEH_02577 4.91e-74 - - - I ko:K06076 - ko00000,ko02000 COG COG2067 Long-chain fatty acid transport protein
HKOPHDEH_02579 7.89e-182 - - - OU ko:K04773 - ko00000,ko01000,ko01002 Peptidase family S49
HKOPHDEH_02582 2.64e-243 - - - S - - - Psort location CytoplasmicMembrane, score 9.97
HKOPHDEH_02583 0.0 - - - C - - - Di-haem oxidoreductase, putative peroxidase
HKOPHDEH_02586 3.84e-191 - - - S ko:K21572 - ko00000,ko02000 Pfam:SusD
HKOPHDEH_02587 6.04e-145 - - - P ko:K21573 - ko00000,ko02000 TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_02588 4.17e-165 queA 2.4.99.17 - H ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKOPHDEH_02589 4.26e-82 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
HKOPHDEH_02590 1.6e-145 - - - JM - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02592 2.73e-11 - - - - - - - -
HKOPHDEH_02593 6.66e-39 - - - - - - - -
HKOPHDEH_02594 7.36e-259 - - - E - - - FAD dependent oxidoreductase
HKOPHDEH_02595 1.09e-196 - - - M - - - ompA family
HKOPHDEH_02599 1.26e-17 - - - - - - - -
HKOPHDEH_02602 4.32e-258 - - - V ko:K01992 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02603 8.05e-155 ybhS - - V ko:K01992 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02605 3.03e-188 - - - - - - - -
HKOPHDEH_02607 2.34e-188 ramA_2 - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02609 0.0 - - - P ko:K07085 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02610 1.07e-57 pitA - - P ko:K03306 - ko00000 Phosphate transporter family
HKOPHDEH_02611 5.96e-128 - 4.2.2.20, 4.2.2.21 - H ko:K08961 - ko00000,ko01000 Chondroitin sulfate ABC lyase
HKOPHDEH_02612 2.42e-237 dus - - H - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKOPHDEH_02613 5.98e-293 - - - G - - - beta-fructofuranosidase activity
HKOPHDEH_02614 9.06e-130 ywqN - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02615 0.0 - - - S - - - COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKOPHDEH_02616 7.3e-71 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HKOPHDEH_02617 8.15e-128 - - - S - - - Psort location OuterMembrane, score 9.49
HKOPHDEH_02618 0.0 - - - M - - - Outer membrane protein, OMP85 family
HKOPHDEH_02619 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_02621 1.07e-256 - 5.1.3.11 - M ko:K16213 - ko00000,ko01000 Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)
HKOPHDEH_02622 1.95e-104 - - - S - - - UpxZ family of transcription anti-terminator antagonists
HKOPHDEH_02623 0.0 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02624 2.61e-09 - - - - - - - -
HKOPHDEH_02626 0.0 pepP 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Psort location Cytoplasmic, score
HKOPHDEH_02627 6.84e-100 - - - CO - - - Thioredoxin
HKOPHDEH_02628 1.04e-118 - - - S - - - Starch-binding module 26
HKOPHDEH_02629 1.63e-166 - - - S - - - Starch-binding module 26
HKOPHDEH_02630 0.0 - - - S ko:K21572 - ko00000,ko02000 Pfam:SusD
HKOPHDEH_02631 9.06e-102 - - - G - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02632 8.34e-282 - - - S - - - COG NOG33609 non supervised orthologous group
HKOPHDEH_02633 4.78e-165 - - - - - - - -
HKOPHDEH_02634 8.84e-68 - - - - - - - -
HKOPHDEH_02637 0.0 - - - M ko:K08676 - ko00000,ko01000,ko01002 Tricorn protease homolog
HKOPHDEH_02640 3.1e-152 - - - L - - - Phage integrase family
HKOPHDEH_02641 2.29e-37 - - - - - - - -
HKOPHDEH_02642 2.66e-24 - - - - - - - -
HKOPHDEH_02643 1.05e-98 - - - - - - - -
HKOPHDEH_02644 1.5e-114 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG NOG32858 non supervised orthologous group
HKOPHDEH_02645 1.28e-155 - - - V ko:K02003 - ko00000,ko00002,ko02000 bacteriocin export ABC transporter, lactococcin 972 group
HKOPHDEH_02646 4.96e-287 - - - V ko:K02004 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02647 1.36e-163 - - - V ko:K02004 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02648 1.25e-93 - - - S - - - protein conserved in bacteria
HKOPHDEH_02649 2.46e-190 - - - H - - - TonB-dependent receptor plug domain
HKOPHDEH_02650 6.15e-200 - - - H - - - TonB-dependent receptor plug domain
HKOPHDEH_02651 9.89e-144 - - - KT - - - COG3279 Response regulator of the LytR AlgR family
HKOPHDEH_02653 0.0 - - - D ko:K09955 - ko00000 protein conserved in bacteria
HKOPHDEH_02654 8.63e-58 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HKOPHDEH_02655 2.87e-308 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Psort location Cytoplasmic, score
HKOPHDEH_02656 2.6e-167 - - - K - - - LytTr DNA-binding domain
HKOPHDEH_02657 2.22e-136 - - - T - - - Histidine kinase
HKOPHDEH_02658 3.87e-283 - - - - - - - -
HKOPHDEH_02659 0.0 - - - G ko:K02429 - ko00000,ko02000 L-fucose H symporter permease
HKOPHDEH_02662 8.67e-237 pseC - - E - - - Belongs to the DegT DnrJ EryC1 family
HKOPHDEH_02663 4.67e-66 - - - C - - - Aldo/keto reductase family
HKOPHDEH_02664 1.4e-87 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HKOPHDEH_02665 3.66e-83 - 3.2.1.35 - G ko:K01197 ko00531,ko01100,map00531,map01100 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylglucosaminidase
HKOPHDEH_02668 6.5e-182 trpC 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HKOPHDEH_02669 1.78e-239 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKOPHDEH_02670 4.3e-123 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Glutamine amidotransferase, class I
HKOPHDEH_02671 6.2e-265 gmd 4.2.1.47 - M ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HKOPHDEH_02672 5.81e-255 sstT - - U - - - Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKOPHDEH_02674 5.66e-240 - - - G - - - Glycosyl hydrolases family 43
HKOPHDEH_02675 4.18e-113 - - - M - - - Outer membrane protein beta-barrel domain
HKOPHDEH_02676 5.68e-110 - - - O - - - Heat shock protein
HKOPHDEH_02677 1.57e-193 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_02678 7.78e-174 comF 2.4.2.14 - S ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 ComF family
HKOPHDEH_02679 4.55e-143 - - - M - - - Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HKOPHDEH_02680 1.33e-129 yajL 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 Psort location Cytoplasmic, score
HKOPHDEH_02681 1.84e-159 - - - M - - - TonB family domain protein
HKOPHDEH_02682 9.89e-86 - - - U ko:K03559 - ko00000,ko02000 Transport energizing protein, ExbD TolR family
HKOPHDEH_02683 7.53e-130 exbB - - U ko:K03561 - ko00000,ko02000 MotA TolQ ExbB proton channel family
HKOPHDEH_02684 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_02685 9.4e-40 - - - H - - - Psort location OuterMembrane, score
HKOPHDEH_02690 0.0 - - - M - - - Outer membrane protein, OMP85 family
HKOPHDEH_02691 7.22e-33 - - - U ko:K03832 - ko00000,ko02000 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HKOPHDEH_02692 2.96e-241 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HKOPHDEH_02693 4.49e-168 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02694 4.51e-190 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HKOPHDEH_02695 7.31e-142 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKOPHDEH_02696 5.68e-113 queF 1.7.1.13 - H ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HKOPHDEH_02697 5.24e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HKOPHDEH_02698 9.73e-155 yhhQ - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HKOPHDEH_02699 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKOPHDEH_02700 3.8e-91 - - - S - - - COG NOG14473 non supervised orthologous group
HKOPHDEH_02701 2.64e-66 bioC 2.1.1.197, 3.1.1.85 - H ko:K02169,ko:K09789 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway
HKOPHDEH_02702 1.69e-52 bioC 2.1.1.197, 3.1.1.85 - H ko:K02169,ko:K09789 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway
HKOPHDEH_02703 1.88e-112 - 3.1.1.85 - S ko:K09789 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Protein of unknown function (DUF452)
HKOPHDEH_02704 1.04e-180 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 COG COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
HKOPHDEH_02705 5.49e-236 glk 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 9.26
HKOPHDEH_02706 7.71e-167 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKOPHDEH_02707 7.19e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKOPHDEH_02708 1.7e-142 - - - L - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02712 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_02714 5.79e-172 - - - P - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02715 4.84e-87 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HKOPHDEH_02716 3.78e-143 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HKOPHDEH_02717 3.55e-95 - - - S - - - YjbR
HKOPHDEH_02718 1.56e-120 - - - L - - - DNA-binding protein
HKOPHDEH_02719 3.09e-178 - - - S - - - NigD-like N-terminal OB domain
HKOPHDEH_02721 0.0 oprM_1 - - MU - - - Efflux transporter, outer membrane factor lipoprotein, NodT family
HKOPHDEH_02722 5.39e-214 bepE_1 - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKOPHDEH_02723 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_02724 1.04e-126 - - - - - - - -
HKOPHDEH_02725 1.5e-76 - - - - - - - -
HKOPHDEH_02726 2.78e-48 - - - - - - - -
HKOPHDEH_02727 3.57e-79 - - - - - - - -
HKOPHDEH_02728 1.02e-49 - - - P ko:K07085 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02729 5.56e-245 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 COG COG0147 Anthranilate para-aminobenzoate synthases component I
HKOPHDEH_02730 5.99e-149 - 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_02731 1.38e-75 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_02733 9e-181 - - - O ko:K05801 - ko00000,ko03110 Psort location Cytoplasmic, score
HKOPHDEH_02734 1.44e-112 ybaK - - H ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKOPHDEH_02735 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKOPHDEH_02736 1.02e-38 - - - - - - - -
HKOPHDEH_02737 1.79e-213 serA 1.1.1.399, 1.1.1.95 - C ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKOPHDEH_02738 2.5e-258 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HKOPHDEH_02739 2.6e-252 - - - S - - - Psort location Cytoplasmic, score
HKOPHDEH_02740 0.0 yngK - - S - - - lipoprotein YddW precursor K01189
HKOPHDEH_02741 0.0 - - - P ko:K21573 - ko00000,ko02000 TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_02742 0.0 - - - K ko:K03088 - ko00000,ko03021 Outer membrane protein beta-barrel domain
HKOPHDEH_02743 5.83e-100 - - - P ko:K03711 - ko00000,ko03000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_02744 2.1e-36 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02745 0.0 - - - H - - - COG NOG06391 non supervised orthologous group
HKOPHDEH_02746 3.4e-48 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKOPHDEH_02747 4.8e-310 prtC - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Psort location Cytoplasmic, score 8.96
HKOPHDEH_02748 5.49e-236 dus - - H - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKOPHDEH_02751 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
HKOPHDEH_02753 0.0 yccM - - C - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_02754 4.58e-214 - 3.2.1.3 GH15 G ko:K01178 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolases family 15
HKOPHDEH_02755 2.31e-286 - - - M - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_02756 6.45e-299 - - - T - - - Psort location CytoplasmicMembrane, score 7.88
HKOPHDEH_02757 0.0 - 3.4.13.19 - E ko:K01273,ko:K01274 - ko00000,ko00537,ko01000,ko01002,ko04147 Renal dipeptidase family protein
HKOPHDEH_02758 3.96e-52 - - - - - - - -
HKOPHDEH_02759 6.41e-172 znuC - - P ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKOPHDEH_02760 6.33e-215 mntA - - P ko:K09815,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0803 ABC-type metal ion transport system, periplasmic component surface adhesin
HKOPHDEH_02761 9.98e-106 mnmC - - S - - - Psort location Cytoplasmic, score
HKOPHDEH_02762 6.93e-184 - - - V ko:K02004 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02766 1.16e-206 - - - P - - - TonB dependent receptor
HKOPHDEH_02767 4.49e-130 cobC 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_02768 0.0 - - - T - - - COG0642 Signal transduction histidine kinase
HKOPHDEH_02769 1.94e-49 - - - T - - - histidine kinase DNA gyrase B
HKOPHDEH_02770 1.94e-212 udp 2.4.2.3 - F ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HKOPHDEH_02771 9.32e-211 - - - S - - - UPF0365 protein
HKOPHDEH_02772 4.49e-49 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_02773 4.43e-61 - - - K - - - Winged helix DNA-binding domain
HKOPHDEH_02774 3.12e-172 - - - NU - - - Type IV pilus biogenesis stability protein PilW
HKOPHDEH_02775 2.46e-138 mtnN 3.2.2.9 - F ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKOPHDEH_02776 5.21e-73 - - - S ko:K09790 - ko00000 Psort location CytoplasmicMembrane, score
HKOPHDEH_02777 0.0 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKOPHDEH_02778 4.56e-78 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Psort location CytoplasmicMembrane, score
HKOPHDEH_02779 3.1e-89 - - - EGP - - - Transporter, major facilitator family protein
HKOPHDEH_02780 3.54e-230 - - - S ko:K01163 - ko00000 Conserved protein
HKOPHDEH_02781 3.09e-149 lrgB - - M - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02782 2.1e-71 lrgA - - S ko:K06518 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
HKOPHDEH_02783 1.39e-259 - - - P - - - TonB dependent receptor
HKOPHDEH_02784 0.0 - - - GM ko:K21572 - ko00000,ko02000 Pfam:SusD
HKOPHDEH_02785 6.4e-113 - 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 COG4845 Chloramphenicol O-acetyltransferase
HKOPHDEH_02786 7.52e-165 - - - S - - - Protein of unknown function (DUF2490)
HKOPHDEH_02787 2.76e-272 - - - N - - - Psort location OuterMembrane, score
HKOPHDEH_02788 1.14e-83 - - - PT - - - Domain of unknown function (DUF4974)
HKOPHDEH_02792 4.1e-199 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKOPHDEH_02794 4.33e-192 idnO 1.1.1.69 - IQ ko:K00046 - ko00000,ko01000 Oxidoreductase, short chain dehydrogenase reductase family protein
HKOPHDEH_02795 1.05e-176 ydfG - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HKOPHDEH_02799 2.91e-127 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02800 8.69e-149 - - - E - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02803 2.23e-150 spk1 2.7.11.1, 6.3.2.4 - S ko:K01921,ko:K08884,ko:K12132 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01001,ko01011 PASTA domain protein
HKOPHDEH_02804 1.36e-27 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HKOPHDEH_02805 2.28e-132 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKOPHDEH_02806 1.41e-303 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_02807 3.59e-167 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HKOPHDEH_02808 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HKOPHDEH_02809 2.15e-48 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA, 67K type
HKOPHDEH_02810 7.16e-280 lpxK 2.7.1.130 - F ko:K00912 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
HKOPHDEH_02811 8.74e-193 deoD 2.4.2.1 - F ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HKOPHDEH_02812 5.79e-288 - - - M ko:K02005 - ko00000 Efflux transporter, RND family, MFP subunit
HKOPHDEH_02813 9.35e-152 - - - V ko:K02003 - ko00000,ko00002,ko02000 bacteriocin export ABC transporter, lactococcin 972 group
HKOPHDEH_02814 7.79e-168 - - - L - - - DNA primase
HKOPHDEH_02817 4.05e-47 - 6.3.5.5 - S ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 ATP-grasp in the biosynthetic pathway with Ter operon
HKOPHDEH_02818 6.4e-90 - 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-dependent decarboxylase, pyridoxal binding domain
HKOPHDEH_02822 6.81e-53 - - - S - - - Domain of unknown function (DUF4440)
HKOPHDEH_02823 5.14e-59 - - - C - - - flavodoxin
HKOPHDEH_02824 5.65e-70 - - - C - - - Flavodoxin
HKOPHDEH_02825 2.38e-125 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02826 1.33e-171 - - - S - - - phosphatase family
HKOPHDEH_02828 1.85e-110 - - - P - - - Psort location OuterMembrane, score 9.52
HKOPHDEH_02829 4.81e-138 - - - C - - - Nitroreductase family
HKOPHDEH_02830 1.38e-251 hpaIIR 3.1.21.4 - L ko:K01155 - ko00000,ko01000,ko02048 COG NOG26934 non supervised orthologous group
HKOPHDEH_02832 4.3e-151 ytrE_3 - - V ko:K02003 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 7.88
HKOPHDEH_02833 9.39e-112 - - - V ko:K02004 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02834 0.0 - - - C ko:K02123 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Belongs to the V-ATPase 116 kDa subunit family
HKOPHDEH_02835 7.76e-89 ntpK - - C ko:K02124 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG COG0636 F0F1-type ATP synthase, subunit c Archaeal vacuolar-type H -ATPase, subunit K
HKOPHDEH_02837 2.13e-150 - - - T - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_02838 9.45e-145 - - - T - - - Psort location Cytoplasmic, score
HKOPHDEH_02839 2.26e-228 - 3.1.1.11 - G ko:K01051 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 COG NOG24911 non supervised orthologous group
HKOPHDEH_02841 6.56e-93 - - - S - - - COG NOG32090 non supervised orthologous group
HKOPHDEH_02842 1.8e-271 merA - - C ko:K21739 - ko00000 COG COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKOPHDEH_02843 7.44e-241 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKOPHDEH_02845 3.54e-43 - - - K - - - Psort location Cytoplasmic, score
HKOPHDEH_02846 0.0 - - - IQ ko:K00666 - ko00000,ko01000,ko01004 Psort location Cytoplasmic, score 9.97
HKOPHDEH_02847 1.52e-90 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKOPHDEH_02848 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKOPHDEH_02851 4.98e-27 - - - S - - - Tetratricopeptide repeat protein
HKOPHDEH_02854 2.51e-35 - - - - - - - -
HKOPHDEH_02855 1.99e-158 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02858 6.18e-73 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 COG0847 DNA polymerase III epsilon subunit and related 3'-5'
HKOPHDEH_02859 2.22e-130 - - - F - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02861 0.0 dbpA 3.6.4.13 - L ko:K05591 - ko00000,ko01000,ko03009 ATP-independent RNA helicase DbpA
HKOPHDEH_02862 6.38e-168 - - - M - - - Outer membrane protein beta-barrel domain
HKOPHDEH_02863 0.0 lysM - - M - - - LysM domain
HKOPHDEH_02866 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HKOPHDEH_02869 2.47e-146 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02870 5.7e-100 - - - I - - - CDP-alcohol phosphatidyltransferase
HKOPHDEH_02871 0.0 eam 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 KamA family
HKOPHDEH_02872 2.33e-139 mug - - L - - - COG3663 G T U mismatch-specific DNA glycosylase
HKOPHDEH_02873 2.91e-228 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02874 2.11e-202 - - - - - - - -
HKOPHDEH_02876 3.02e-316 ppk 2.7.4.1 - H ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKOPHDEH_02877 0.0 norM - - V - - - MATE efflux family protein
HKOPHDEH_02878 7.71e-169 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HKOPHDEH_02880 3.27e-227 yccM - - C - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_02881 7.83e-49 yccM - - C - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_02884 1.22e-142 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HKOPHDEH_02885 0.0 - - - E ko:K03307 - ko00000 alkaline phosphatase synthesis sensor protein phoR K07636
HKOPHDEH_02887 2.66e-303 - - - S - - - P-loop ATPase and inactivated derivatives
HKOPHDEH_02888 7.67e-56 - - - S - - - Domain of unknown function (DUF4248)
HKOPHDEH_02891 1.19e-195 - - - C - - - Protein of unknown function (DUF2764)
HKOPHDEH_02892 4.63e-104 - - - C ko:K02121 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG NOG11642 non supervised orthologous group
HKOPHDEH_02893 2.84e-21 - - - - - - - -
HKOPHDEH_02894 7.02e-190 - - - S - - - COG NOG11650 non supervised orthologous group
HKOPHDEH_02895 2.05e-205 - - - M - - - fibronectin type III domain protein
HKOPHDEH_02896 2.06e-285 - - - E - - - Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKOPHDEH_02897 2.59e-151 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKOPHDEH_02898 1.98e-32 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine biosynthesis protein ThiS
HKOPHDEH_02899 3.5e-126 - - - S - - - COG NOG35345 non supervised orthologous group
HKOPHDEH_02900 2.27e-308 - - - S - - - DNA-binding protein with the Helix-hairpin-helix motif
HKOPHDEH_02901 4.51e-189 - - - L - - - DNA metabolism protein
HKOPHDEH_02902 8.48e-92 - - - M - - - Protein of unknown function (DUF3575)
HKOPHDEH_02903 6.63e-301 - - - M - - - COG NOG23378 non supervised orthologous group
HKOPHDEH_02904 4.62e-182 - - - I - - - Protein of unknown function (DUF1460)
HKOPHDEH_02905 2e-223 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 COG3250 Beta-galactosidase beta-glucuronidase
HKOPHDEH_02906 4.61e-62 - - - K - - - Transcription termination antitermination factor NusG
HKOPHDEH_02907 1.48e-249 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02909 1.04e-98 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HKOPHDEH_02910 1.5e-63 - - - MU - - - Psort location OuterMembrane, score
HKOPHDEH_02911 0.0 - - - T ko:K02481 - ko00000,ko02022 acetoacetate metabolism regulatory protein AtoC K07714
HKOPHDEH_02913 4.96e-270 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HKOPHDEH_02914 8.87e-132 yigZ - - S - - - YigZ family
HKOPHDEH_02916 8.17e-149 - - - S - - - COG NOG26634 non supervised orthologous group
HKOPHDEH_02917 4.61e-85 - - - S - - - COG NOG26634 non supervised orthologous group
HKOPHDEH_02918 0.0 gcvP 1.4.4.2 - E ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HKOPHDEH_02919 2.8e-92 gcvP 1.4.4.2 - E ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HKOPHDEH_02920 0.0 - - - E - - - Domain of unknown function (DUF4374)
HKOPHDEH_02921 2.48e-57 - - - S - - - COG NOG23371 non supervised orthologous group
HKOPHDEH_02922 3.67e-136 - - - I - - - Acyltransferase
HKOPHDEH_02923 5.23e-163 ramA_1 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 hydrolase, carbon-nitrogen family
HKOPHDEH_02924 1.34e-135 - - - S - - - COG NOG26858 non supervised orthologous group
HKOPHDEH_02925 0.0 alaC - - E - - - Aminotransferase, class I II
HKOPHDEH_02926 7.39e-103 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_02927 1.74e-209 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKOPHDEH_02928 1.1e-170 pdxJ 2.6.99.2 - H ko:K03474 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HKOPHDEH_02929 0.0 aspD 4.1.1.12 - E ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 ko00000,ko00001,ko01000 COG COG0436 Aspartate tyrosine aromatic aminotransferase
HKOPHDEH_02932 9.87e-122 cobU 2.7.1.156, 2.7.7.62 - H ko:K02231 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 bifunctional cobalamin biosynthesis protein
HKOPHDEH_02934 1e-130 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HKOPHDEH_02935 1.45e-78 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HKOPHDEH_02936 3.6e-248 - - - M - - - Peptidase family S41
HKOPHDEH_02937 2.37e-120 - - - S ko:K07095 - ko00000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_02939 3.1e-122 - - - M ko:K01993 - ko00000 Auxiliary transport protein, membrane fusion protein (MFP) family protein
HKOPHDEH_02940 5.31e-282 - - - CP ko:K01992 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HKOPHDEH_02941 7.54e-76 - - - G - - - Glycosyl hydrolases family 43
HKOPHDEH_02942 0.0 - - - S - - - COG NOG19133 non supervised orthologous group
HKOPHDEH_02943 3.74e-292 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase, glutamine-hydrolyzing
HKOPHDEH_02944 5.26e-09 - - - H - - - COG NOG08812 non supervised orthologous group
HKOPHDEH_02945 1.08e-131 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKOPHDEH_02946 2.41e-84 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HKOPHDEH_02947 8.91e-121 paiA - - K - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02948 3.84e-281 - - - P ko:K03305 - ko00000 amino acid peptide transporter
HKOPHDEH_02949 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HKOPHDEH_02950 4.69e-151 spk1 2.7.11.1, 6.3.2.4 - S ko:K01921,ko:K08884,ko:K12132 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01001,ko01011 PASTA domain protein
HKOPHDEH_02951 4.46e-276 - - - M - - - ompA family
HKOPHDEH_02952 2.95e-239 ldhA 1.1.1.28 - C ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKOPHDEH_02953 5.57e-107 - - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
HKOPHDEH_02954 1.56e-124 lemA - - S ko:K03744 - ko00000 LemA family
HKOPHDEH_02955 1.42e-145 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
HKOPHDEH_02956 1.36e-253 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKOPHDEH_02957 0.0 - - - E - - - Protein of unknown function (DUF1593)
HKOPHDEH_02958 1.61e-85 - - - S - - - COG NOG28211 non supervised orthologous group
HKOPHDEH_02959 2.07e-171 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02962 2e-197 ykfB 5.1.1.20, 5.1.1.3 - M ko:K01776,ko:K19802 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the mandelate racemase muconate lactonizing enzyme family
HKOPHDEH_02963 0.0 ctp 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HKOPHDEH_02964 8.13e-115 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
HKOPHDEH_02968 3.58e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKOPHDEH_02970 2e-142 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HKOPHDEH_02975 1.29e-182 - - - S - - - COG NOG27188 non supervised orthologous group
HKOPHDEH_02976 1.9e-54 - - - S - - - Ser Thr phosphatase family protein
HKOPHDEH_02977 2.11e-220 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKOPHDEH_02980 1.27e-251 - - - S - - - Psort location CytoplasmicMembrane, score
HKOPHDEH_02981 9.99e-246 pseB 4.2.1.115 - M ko:K15894 ko00520,map00520 ko00000,ko00001,ko01000 Male sterility protein
HKOPHDEH_02982 6.05e-113 - - - S - - - Psort location Cytoplasmic, score 8.96
HKOPHDEH_02985 5.77e-102 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 bacterioferritin comigratory protein
HKOPHDEH_02986 3.49e-145 LYS1 1.5.1.7 - E ko:K00290 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 COG1748 Saccharopine dehydrogenase and related
HKOPHDEH_02987 4.05e-69 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKOPHDEH_02988 5.16e-115 - - - S - - - COG NOG29454 non supervised orthologous group
HKOPHDEH_02989 1.56e-149 ispE 2.7.1.148 - F ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKOPHDEH_02991 6.49e-115 - - - G - - - Putative collagen-binding domain of a collagenase
HKOPHDEH_02994 6.12e-197 - - - H - - - Outer membrane protein beta-barrel family
HKOPHDEH_02995 7.1e-99 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKOPHDEH_02996 1.21e-104 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKOPHDEH_02997 1.6e-75 ypjD - - S - - - MazG nucleotide pyrophosphohydrolase domain

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)