ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HMIECIIO_00007 3.18e-101 - - - - - - - -
HMIECIIO_00011 4.6e-05 - - - - - - - -
HMIECIIO_00014 0.00011 xerA - - L ko:K03733,ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules
HMIECIIO_00016 0.0 - 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 RQC
HMIECIIO_00022 3.45e-178 - - - S - - - mannose-ethanolamine phosphotransferase activity
HMIECIIO_00024 2.91e-114 - - - S ko:K03748 - ko00000 DUF218 domain
HMIECIIO_00026 5.44e-104 - - - J - - - YjgF/chorismate_mutase-like, putative endoribonuclease
HMIECIIO_00027 0.0 - - - - - - - -
HMIECIIO_00028 2.46e-113 - 1.16.3.2 - P ko:K02217 - ko00000,ko01000 Ferritin-like domain
HMIECIIO_00030 1e-91 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HMIECIIO_00031 1.25e-307 - 4.2.1.20 - E ko:K06001 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HMIECIIO_00032 2.51e-234 - 2.7.1.221 - S ko:K07102 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Phosphotransferase enzyme family
HMIECIIO_00033 0.0 - - - T - - - Chase2 domain
HMIECIIO_00034 2.34e-107 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Low molecular weight phosphatase family
HMIECIIO_00035 2.7e-113 - - - S - - - L,D-transpeptidase catalytic domain
HMIECIIO_00036 0.0 - 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome bd terminal oxidase subunit I
HMIECIIO_00037 1.21e-244 - 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome bd terminal oxidase subunit II
HMIECIIO_00038 0.0 - 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 2-oxoglutarate dehydrogenase C-terminal
HMIECIIO_00039 5.45e-225 - 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HMIECIIO_00040 8.04e-60 - 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 nucleotidyltransferase activity
HMIECIIO_00041 5.53e-96 - - - S - - - Nucleotidyltransferase substrate binding protein like
HMIECIIO_00042 0.0 - 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HMIECIIO_00043 2.31e-313 - 3.5.4.28, 3.5.4.31 - F ko:K12960 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Amidohydrolase family
HMIECIIO_00044 6.65e-160 - - - M ko:K16079 - ko00000,ko02000 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HMIECIIO_00045 0.0 - 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Glycosyl hydrolases family 35
HMIECIIO_00046 0.0 - - - E ko:K13893 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HMIECIIO_00047 0.0 - - - H ko:K02014 - ko00000,ko02000 TonB dependent receptor
HMIECIIO_00048 0.0 cobQ - - H - - - Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HMIECIIO_00049 7.18e-234 cobD 6.3.1.10 - H ko:K02227 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HMIECIIO_00050 4.02e-239 cobT 2.4.2.21 - H ko:K00768 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HMIECIIO_00051 1.62e-172 cobS 2.7.8.26 - H ko:K02233 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HMIECIIO_00052 1.65e-207 - - - G - - - myo-inosose-2 dehydratase activity
HMIECIIO_00053 4.46e-127 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 - H ko:K02231,ko:K02232 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 cobinamide kinase activity
HMIECIIO_00056 2.18e-269 - - - K - - - Periplasmic binding protein-like domain
HMIECIIO_00057 3.67e-216 - - - M - - - Carbohydrate esterase, sialic acid-specific acetylesterase
HMIECIIO_00058 3.87e-301 - 2.7.1.11, 2.7.1.90 - H ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HMIECIIO_00060 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 PFAM Glycoside hydrolase, family 20, catalytic core
HMIECIIO_00061 0.0 rarA - - L ko:K07478 - ko00000 MgsA AAA+ ATPase C terminal
HMIECIIO_00062 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
HMIECIIO_00063 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Beta galactosidase small chain
HMIECIIO_00064 3.64e-183 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HMIECIIO_00065 8.87e-269 - - - L - - - Belongs to the 'phage' integrase family
HMIECIIO_00066 0.0 - 4.1.1.19 - E ko:K01585 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Pyridoxal-dependent decarboxylase, pyridoxal binding domain
HMIECIIO_00067 7.45e-301 - 4.1.1.96 - E ko:K13747 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase, C-terminal sheet domain
HMIECIIO_00069 0.0 - - - P - - - Sulfatase
HMIECIIO_00070 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Leucyl-tRNA synthetase, Domain 2
HMIECIIO_00071 3.85e-152 - 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribulose-phosphate 3 epimerase family
HMIECIIO_00072 3.25e-223 - 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Phosphatidylserine decarboxylase
HMIECIIO_00075 0.0 - 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
HMIECIIO_00076 7.83e-140 - - - S - - - Haloacid dehalogenase-like hydrolase
HMIECIIO_00077 2.34e-43 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S20
HMIECIIO_00079 6.25e-288 - 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 LytB protein
HMIECIIO_00080 8.69e-261 - - - J ko:K05541 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMIECIIO_00081 1.2e-284 - - - E - - - Transglutaminase-like superfamily
HMIECIIO_00082 1.84e-202 - - - I - - - Diacylglycerol kinase catalytic domain
HMIECIIO_00083 2.91e-182 - 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HMIECIIO_00084 7.21e-203 folD 1.5.1.5, 3.5.4.9 - H ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMIECIIO_00085 7.21e-183 - - - S ko:K09778 - ko00000 Domain of unknown function (DUF374)
HMIECIIO_00086 0.0 - - - - - - - -
HMIECIIO_00087 0.0 - - - NU ko:K02453 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 Bacterial type II and III secretion system protein
HMIECIIO_00088 0.0 - - - G - - - Alpha amylase, catalytic domain
HMIECIIO_00089 0.0 - 2.7.7.19 - J ko:K00970 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Poly A polymerase head domain
HMIECIIO_00090 4.81e-311 - - - O - - - peroxiredoxin activity
HMIECIIO_00091 0.0 - - - P ko:K03306 - ko00000 phosphate transporter
HMIECIIO_00092 0.0 - 3.6.4.13 - L ko:K03579 - ko00000,ko01000 ATP-dependent helicase C-terminal
HMIECIIO_00093 8.06e-216 - 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Cytidylyltransferase family
HMIECIIO_00094 0.0 - 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 tail specific protease
HMIECIIO_00095 0.0 - - - E - - - Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMIECIIO_00098 3.72e-187 - 3.4.13.22 - M ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-ala-D-ala dipeptidase
HMIECIIO_00099 0.0 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMIECIIO_00100 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMIECIIO_00101 0.0 - - - - ko:K07403 - ko00000 -
HMIECIIO_00102 0.0 - 2.8.4.4 - J ko:K14441 - ko00000,ko01000,ko03009 Uncharacterized protein family UPF0004
HMIECIIO_00104 0.0 - 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
HMIECIIO_00105 0.0 pmp21 - - T - - - pathogenesis
HMIECIIO_00106 5.71e-202 - - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase (PrmA)
HMIECIIO_00107 4.37e-141 - 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Lumazine binding domain
HMIECIIO_00108 0.0 - - - P - - - Putative Na+/H+ antiporter
HMIECIIO_00109 0.0 - - - G - - - Polysaccharide deacetylase
HMIECIIO_00111 3.6e-306 nuoD 1.6.5.3 - C ko:K00333 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HMIECIIO_00112 2.88e-142 - 1.6.5.3 - C ko:K00334 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Thioredoxin-like [2Fe-2S] ferredoxin
HMIECIIO_00113 0.0 - 1.6.5.3 - C ko:K00335 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
HMIECIIO_00114 0.0 - 1.6.5.3 - C ko:K00336 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
HMIECIIO_00115 1.04e-309 nuoH 1.6.5.3 - C ko:K00337 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HMIECIIO_00116 1.8e-124 nuoI 1.6.5.3 - C ko:K00338 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HMIECIIO_00117 6.53e-158 - 1.6.5.3 - C ko:K00339 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NADH-ubiquinone/plastoquinone oxidoreductase chain 6
HMIECIIO_00118 6.01e-61 nuoK 1.6.5.3 - C ko:K00340 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HMIECIIO_00119 0.0 - 1.6.5.3 - CP ko:K00341 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
HMIECIIO_00120 0.0 - 1.6.5.3 - C ko:K00342 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Proton-conducting membrane transporter
HMIECIIO_00121 0.0 nuoN 1.6.5.3 - C ko:K00343 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HMIECIIO_00122 3.12e-219 - - - E - - - Domain of unknown function (DUF3472)
HMIECIIO_00124 7.43e-107 - - - - - - - -
HMIECIIO_00125 2.39e-126 - - - S - - - Pfam:DUF59
HMIECIIO_00126 0.0 - 5.2.1.8 - O ko:K03770 - ko00000,ko01000,ko03110 PPIC-type PPIASE domain
HMIECIIO_00127 0.0 - - - E ko:K03305 - ko00000 POT family
HMIECIIO_00128 1.07e-238 - 2.5.1.90 - H ko:K02523 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Polyprenyl synthetase
HMIECIIO_00129 2.37e-291 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HMIECIIO_00130 3.98e-190 - - - L ko:K06864 - ko00000 tRNA processing
HMIECIIO_00131 9.28e-170 - - - S ko:K06898 - ko00000 AIR carboxylase
HMIECIIO_00132 0.0 - - - S - - - Glycosyl hydrolase-like 10
HMIECIIO_00133 1.74e-157 - 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Iron/manganese superoxide dismutases, alpha-hairpin domain
HMIECIIO_00134 1.26e-271 - - - IM - - - Cytidylyltransferase-like
HMIECIIO_00135 0.0 murJ - - S ko:K03980 - ko00000,ko01011,ko02000 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HMIECIIO_00136 1.57e-280 - 2.6.1.1 - E ko:K00812 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
HMIECIIO_00137 2.83e-110 - - - S - - - Control of competence regulator ComK, YlbF/YmcA
HMIECIIO_00138 1.04e-244 - - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMIECIIO_00139 0.0 - - - NU ko:K02652 - ko00000,ko02035,ko02044 Type II/IV secretion system protein
HMIECIIO_00140 0.0 - - - NU ko:K02652 - ko00000,ko02035,ko02044 Type II secretion system (T2SS), protein E, N-terminal domain
HMIECIIO_00141 7.26e-285 - - - NU ko:K02653 - ko00000,ko02035,ko02044 Type II secretion system (T2SS), protein F
HMIECIIO_00142 1.34e-07 - - - NU - - - Prokaryotic N-terminal methylation motif
HMIECIIO_00143 4.12e-225 - - - M - - - Glycosyl transferase family 2
HMIECIIO_00144 1.71e-201 - - - S - - - Glycosyltransferase like family 2
HMIECIIO_00145 1.3e-104 - 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 NDK
HMIECIIO_00146 1.26e-214 - - - - - - - -
HMIECIIO_00147 3.51e-136 - 5.4.99.20 - J ko:K06181 - ko00000,ko01000,ko03009 RNA pseudouridylate synthase
HMIECIIO_00148 1.5e-44 - 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 RNA polymerase activity
HMIECIIO_00149 6.68e-103 smpB - - O ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMIECIIO_00150 4.12e-139 - - - L - - - RNase_H superfamily
HMIECIIO_00151 3.86e-112 - 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMIECIIO_00152 4.28e-274 - 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Citrate synthase, C-terminal domain
HMIECIIO_00153 9.76e-153 - - - O - - - Glycoprotease family
HMIECIIO_00154 5.98e-212 - - - - - - - -
HMIECIIO_00157 2.89e-123 - 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
HMIECIIO_00159 3.91e-289 - - - C - - - Iron-containing alcohol dehydrogenase
HMIECIIO_00160 0.0 - - - S - - - Alpha-2-macroglobulin family
HMIECIIO_00161 1.52e-191 dpnC 3.1.21.4 - L ko:K01155 - ko00000,ko01000,ko02048 Dam-replacing family
HMIECIIO_00162 5.31e-212 MA20_36650 - - EG - - - spore germination
HMIECIIO_00163 0.0 - - - L - - - PD-(D/E)XK nuclease superfamily
HMIECIIO_00164 0.0 - - - L - - - UvrD/REP helicase N-terminal domain
HMIECIIO_00167 0.0 - - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 Peptidase family M50
HMIECIIO_00168 6.39e-80 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMIECIIO_00169 2.91e-38 - - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L35
HMIECIIO_00170 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMIECIIO_00174 1.53e-07 - - - KLT - - - Lanthionine synthetase C-like protein
HMIECIIO_00175 6.29e-41 - - - S - - - von Willebrand factor type A domain
HMIECIIO_00176 9.51e-27 - - - V - - - Restriction endonuclease
HMIECIIO_00177 1.29e-161 - - - K - - - filamentation induced by cAMP protein Fic
HMIECIIO_00178 7.44e-125 - - - S - - - Virulence protein RhuM family
HMIECIIO_00179 1.07e-58 - - - S ko:K07126 - ko00000 beta-lactamase activity
HMIECIIO_00186 7.55e-05 - - - S - - - TM2 domain
HMIECIIO_00189 5.53e-40 - - - - - - - -
HMIECIIO_00190 1.58e-92 - - - L - - - PD-(D/E)XK nuclease superfamily
HMIECIIO_00191 2.63e-101 - - - L ko:K07448 - ko00000,ko02048 HB1, ASXL, restriction endonuclease HTH domain
HMIECIIO_00192 0.0 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HMIECIIO_00193 8e-101 - 3.1.21.3 - L ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HMIECIIO_00194 5.66e-27 - - - DK - - - Fic/DOC family
HMIECIIO_00195 0.0 hsdR - - V - - - Subunit R is required for both nuclease and ATPase activities, but not for modification
HMIECIIO_00197 3.73e-45 - - - L - - - Domain of unknown function (DUF932)
HMIECIIO_00204 4.84e-36 - - - S - - - zeta toxin
HMIECIIO_00205 3.04e-167 - - - S - - - Pfam:HipA_N
HMIECIIO_00206 6e-37 - - - K - - - sequence-specific DNA binding
HMIECIIO_00208 2.78e-05 - - - L - - - Belongs to the 'phage' integrase family
HMIECIIO_00209 4.12e-275 - - - G - - - Major Facilitator Superfamily
HMIECIIO_00210 5.49e-85 nuoA 1.6.5.3 - C ko:K00330 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HMIECIIO_00212 3.79e-195 supH - - Q - - - phosphatase activity
HMIECIIO_00213 0.0 legA 3.5.1.2 - G ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 response to abiotic stimulus
HMIECIIO_00214 0.0 - - - EG - - - BNR repeat-like domain
HMIECIIO_00215 5.24e-186 - - - E - - - PFAM lipolytic protein G-D-S-L family
HMIECIIO_00216 8.08e-189 - - - E - - - PFAM lipolytic protein G-D-S-L family
HMIECIIO_00217 0.0 - 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
HMIECIIO_00218 1.35e-191 - 1.97.1.4 - C ko:K04069 - ko00000,ko01000 4Fe-4S single cluster domain
HMIECIIO_00219 0.0 - 2.3.1.241 - M ko:K02517 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Glycosyltransferase family 9 (heptosyltransferase)
HMIECIIO_00220 1.08e-63 - - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L36
HMIECIIO_00221 4.15e-287 - 2.3.1.31 - E ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko01000 alpha/beta hydrolase fold
HMIECIIO_00224 3.97e-07 - - - S - - - Metallo-beta-lactamase superfamily
HMIECIIO_00225 5.79e-31 - - - E - - - GDSL-like Lipase/Acylhydrolase
HMIECIIO_00227 6.2e-89 - - - O - - - response to oxidative stress
HMIECIIO_00228 0.0 - - - T - - - pathogenesis
HMIECIIO_00230 5.46e-188 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HMIECIIO_00231 3.6e-287 - 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HMIECIIO_00232 2.94e-155 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 N-(5'phosphoribosyl)anthranilate (PRA) isomerase
HMIECIIO_00233 1.67e-177 - 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Indole-3-glycerol phosphate synthase
HMIECIIO_00234 0.0 trpD 2.4.2.18, 4.1.3.27 - E ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HMIECIIO_00235 0.0 - 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I, N terminal region
HMIECIIO_00239 0.0 hppA 3.6.1.1 - C ko:K15987 ko00190,map00190 ko00000,ko00001,ko01000 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
HMIECIIO_00240 4.06e-244 - - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
HMIECIIO_00241 6.92e-183 - 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
HMIECIIO_00242 7.31e-247 - - - NU - - - Prokaryotic N-terminal methylation motif
HMIECIIO_00243 9.06e-189 - - - - - - - -
HMIECIIO_00244 3.26e-173 - - - NU ko:K02457,ko:K08084 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 protein transport across the cell outer membrane
HMIECIIO_00245 1.16e-242 - - - S - - - Endonuclease/Exonuclease/phosphatase family
HMIECIIO_00246 6.91e-165 - - - K ko:K03088 - ko00000,ko03021 Sigma-70 region 2
HMIECIIO_00247 0.0 - - - KT - - - Sigma factor PP2C-like phosphatases
HMIECIIO_00248 9.77e-296 - - - EGP - - - Major facilitator Superfamily
HMIECIIO_00249 0.0 - - - M - - - Peptidase M60-like family
HMIECIIO_00250 7.32e-215 - - - S - - - haloacid dehalogenase-like hydrolase
HMIECIIO_00251 1.85e-304 - - - M - - - OmpA family
HMIECIIO_00252 3.63e-270 - - - E - - - serine-type peptidase activity
HMIECIIO_00253 3.06e-286 - - - S ko:K11720 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Predicted permease YjgP/YjgQ family
HMIECIIO_00254 6.65e-169 - - - S - - - HAD-hyrolase-like
HMIECIIO_00256 1.54e-217 - 2.3.1.39 - I ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Acyl transferase domain
HMIECIIO_00257 4.19e-87 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HMIECIIO_00258 2.95e-262 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMIECIIO_00259 1.38e-257 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Possible lysine decarboxylase
HMIECIIO_00260 3.26e-278 - 3.4.23.43 - NOU ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type IV leader peptidase family
HMIECIIO_00262 0.0 secD - - U ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HMIECIIO_00263 9.72e-227 - 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
HMIECIIO_00264 1.28e-172 - - - T - - - Outer membrane lipoprotein-sorting protein
HMIECIIO_00265 3.17e-166 - - - S ko:K05810 - ko00000,ko01000 Multi-copper polyphenol oxidoreductase laccase
HMIECIIO_00266 1.12e-217 - - - - - - - -
HMIECIIO_00268 4.49e-169 - 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Type I 3-dehydroquinase
HMIECIIO_00269 3.1e-217 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
HMIECIIO_00272 7.58e-209 - - - J ko:K01894 - ko00000,ko01000,ko01007,ko03016 tRNA synthetases class I (E and Q), catalytic domain
HMIECIIO_00273 0.0 - - - P - - - Citrate transporter
HMIECIIO_00274 4.39e-145 - 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
HMIECIIO_00275 4.1e-193 - - - S - - - Domain of unknown function (DUF1732)
HMIECIIO_00276 0.0 - 2.6.1.66 - E ko:K00835 ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
HMIECIIO_00279 9.1e-237 - - - CO - - - Protein of unknown function, DUF255
HMIECIIO_00280 1.52e-173 zupT - - P ko:K07238 - ko00000,ko02000 transporter
HMIECIIO_00281 4.82e-220 - - - L - - - Membrane
HMIECIIO_00282 9e-254 - 2.7.1.11, 2.7.1.90 - G ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Phosphofructokinase
HMIECIIO_00283 3.37e-224 - - - M - - - D-alanyl-D-alanine carboxypeptidase
HMIECIIO_00286 4.4e-212 - 1.1.1.262 - H ko:K00097 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Pyridoxal phosphate biosynthetic protein PdxA
HMIECIIO_00287 6.37e-60 - - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Ribosomal protein S6
HMIECIIO_00288 6.22e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMIECIIO_00289 1.48e-141 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Imidazoleglycerol-phosphate dehydratase
HMIECIIO_00291 1.51e-132 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HMIECIIO_00292 4.58e-220 prs 2.7.6.1 - EF ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMIECIIO_00293 1.19e-229 - - - C - - - Transmembrane exosortase (Exosortase_EpsH)
HMIECIIO_00294 1.76e-173 - - - S - - - Protein of unknown function (DUF3485)
HMIECIIO_00295 5.95e-167 pks6 - - Q - - - amino acid activation for nonribosomal peptide biosynthetic process
HMIECIIO_00296 6.29e-151 - - - - - - - -
HMIECIIO_00297 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
HMIECIIO_00298 0.0 - 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Peptidase S24-like
HMIECIIO_00299 1.02e-228 - 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Squalene/phytoene synthase
HMIECIIO_00300 0.0 - - - M - - - Parallel beta-helix repeats
HMIECIIO_00301 2.96e-242 - 3.1.3.18 - F ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
HMIECIIO_00302 1.34e-175 - 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMIECIIO_00303 1.2e-262 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMIECIIO_00304 1.16e-114 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMIECIIO_00305 3.65e-60 - - - S ko:K09131 - ko00000 DUF167
HMIECIIO_00306 4.5e-176 - 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis protein
HMIECIIO_00308 7.06e-249 - - - - - - - -
HMIECIIO_00309 1.14e-126 - - - M - - - Polymer-forming cytoskeletal
HMIECIIO_00310 2.41e-148 - - - M - - - Polymer-forming cytoskeletal
HMIECIIO_00311 0.0 - - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 ATPases associated with a variety of cellular activities
HMIECIIO_00313 7.7e-31 - - - S ko:K07126 - ko00000 Sel1-like repeats.
HMIECIIO_00314 3.39e-109 - - - S - - - Putative zinc- or iron-chelating domain
HMIECIIO_00315 2.26e-306 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HMIECIIO_00316 1.44e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Semialdehyde dehydrogenase, NAD binding domain
HMIECIIO_00318 0.0 - - - ET ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
HMIECIIO_00319 1.77e-166 - 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HMIECIIO_00320 4.37e-124 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 adenylate kinase activity
HMIECIIO_00321 0.0 - - - S - - - Tetratricopeptide repeat
HMIECIIO_00322 3.17e-171 - 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 RNA pseudouridylate synthase
HMIECIIO_00323 1.07e-192 - 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 RNA pseudouridylate synthase
HMIECIIO_00324 1.51e-152 - 1.5.1.34 - C ko:K10679 ko00633,ko01120,map00633,map01120 ko00000,ko00001,ko01000 Nitroreductase family
HMIECIIO_00325 0.0 - - - M ko:K04744 - ko00000,ko02000 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HMIECIIO_00326 0.0 - - - M - - - NPCBM/NEW2 domain
HMIECIIO_00327 0.0 - - - G - - - Glycogen debranching enzyme
HMIECIIO_00328 1.83e-231 - 1.1.1.37 - C ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible oxidation of malate to oxaloacetate
HMIECIIO_00329 9.45e-317 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 UDP binding domain
HMIECIIO_00333 1.89e-100 - - - MP - - - regulation of cell-substrate adhesion
HMIECIIO_00337 2.59e-75 - - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HMIECIIO_00338 4.05e-242 tilS 6.3.4.19 - D ko:K04075 - ko00000,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMIECIIO_00339 1.63e-258 - 2.3.1.8 - C ko:K00625 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphate acetyl/butaryl transferase
HMIECIIO_00340 5.56e-214 - 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 PHP domain
HMIECIIO_00342 1e-252 - - - S - - - Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HMIECIIO_00343 0.0 - - - G - - - Major Facilitator Superfamily
HMIECIIO_00344 3.12e-294 - - - - - - - -
HMIECIIO_00345 0.0 - - - L - - - TRCF
HMIECIIO_00346 0.0 - - - S ko:K07126 - ko00000 beta-lactamase activity
HMIECIIO_00347 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 myo-inosose-2 dehydratase activity
HMIECIIO_00348 4.53e-239 - - - - - - - -
HMIECIIO_00349 1.36e-284 pgk 2.7.2.3 - G ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglycerate kinase
HMIECIIO_00350 1.67e-249 - 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
HMIECIIO_00351 1.09e-148 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMIECIIO_00353 3.37e-133 - - - M - - - Polysaccharide biosynthesis/export protein
HMIECIIO_00354 0.0 - - - D - - - Chain length determinant protein
HMIECIIO_00355 8.04e-298 - - - - - - - -
HMIECIIO_00359 0.0 - - - P ko:K03306 - ko00000 phosphate transporter
HMIECIIO_00360 5.31e-99 - - - S - - - peptidase
HMIECIIO_00361 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMIECIIO_00362 2.2e-61 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMIECIIO_00363 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 MreB/Mbl protein
HMIECIIO_00364 0.0 - - - M - - - Glycosyl transferase 4-like domain
HMIECIIO_00365 4.65e-279 - - - S - - - COG0790 FOG TPR repeat, SEL1 subfamily
HMIECIIO_00366 1.71e-239 - - - O ko:K04655 - ko00000 AIR synthase related protein, N-terminal domain
HMIECIIO_00367 3.17e-261 - - - O ko:K04654 - ko00000 Hydrogenase formation hypA family
HMIECIIO_00368 2.74e-50 - - - O ko:K04653 - ko00000 HupF/HypC family
HMIECIIO_00369 0.0 - - - O ko:K04656 - ko00000 HypF finger
HMIECIIO_00370 1.44e-175 hypB - - KO ko:K04652 - ko00000,ko03110 CobW/HypB/UreG, nucleotide-binding domain
HMIECIIO_00371 7.37e-311 - 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Histidyl-tRNA synthetase
HMIECIIO_00372 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HMIECIIO_00377 4.02e-262 - 2.3.1.47 - H ko:K00652 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
HMIECIIO_00378 5.11e-285 - - - IQ - - - Beta-ketoacyl synthase, C-terminal domain
HMIECIIO_00379 0.0 - 3.1.1.1 - S ko:K03928 - ko00000,ko01000 thiolester hydrolase activity
HMIECIIO_00380 4.38e-286 - - - S - - - Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HMIECIIO_00381 9.4e-148 - - - IQ - - - RmlD substrate binding domain
HMIECIIO_00382 0.0 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 GcpE protein
HMIECIIO_00383 0.0 - - - M - - - Bacterial membrane protein, YfhO
HMIECIIO_00384 8.75e-198 - 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HMIECIIO_00385 4.03e-120 - - - - - - - -
HMIECIIO_00386 3.85e-194 - 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 CDP-alcohol phosphatidyltransferase
HMIECIIO_00387 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMIECIIO_00388 5.59e-227 - - - M ko:K01993 - ko00000 HlyD family secretion protein
HMIECIIO_00389 0.0 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMIECIIO_00390 1.2e-242 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HMIECIIO_00391 3.08e-246 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HMIECIIO_00394 1.16e-301 nupG - - G ko:K03289,ko:K03301,ko:K08218,ko:K11537 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
HMIECIIO_00395 7.19e-260 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMIECIIO_00396 4.86e-110 msrB 1.8.4.11, 1.8.4.12 - O ko:K07305,ko:K12267 - ko00000,ko01000 peptide-methionine (R)-S-oxide reductase activity
HMIECIIO_00398 3.9e-306 - 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMIECIIO_00400 3.08e-146 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMIECIIO_00401 2.37e-46 - - - J - - - One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMIECIIO_00402 0.0 - - - - - - - -
HMIECIIO_00403 0.0 - - - S - - - Sodium:neurotransmitter symporter family
HMIECIIO_00404 3.6e-152 - 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
HMIECIIO_00405 2.94e-208 - - - M - - - Mechanosensitive ion channel
HMIECIIO_00406 4.62e-165 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Amino acid kinase family
HMIECIIO_00407 2.53e-120 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMIECIIO_00408 9.17e-70 - - - M - - - Polymer-forming cytoskeletal
HMIECIIO_00409 1.7e-101 - - - K - - - DNA-binding transcription factor activity
HMIECIIO_00410 4.31e-231 - - - J - - - Belongs to the universal ribosomal protein uS2 family
HMIECIIO_00411 5.03e-229 - - - L - - - Elongator protein 3, MiaB family, Radical SAM
HMIECIIO_00412 2.74e-95 - - - S - - - Maltose acetyltransferase
HMIECIIO_00413 4.72e-153 - - - H - - - HD superfamily hydrolase involved in NAD metabolism
HMIECIIO_00414 0.0 - - - S ko:K07263 - ko00000,ko01000,ko01002 Insulinase (Peptidase family M16)
HMIECIIO_00416 7.65e-101 - - - M ko:K06077 - ko00000 Glycine zipper 2TM domain
HMIECIIO_00417 6.15e-234 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
HMIECIIO_00418 4.97e-138 - - - P ko:K02039 - ko00000 PhoU domain
HMIECIIO_00419 4.49e-186 - 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMIECIIO_00420 9.14e-223 - - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 PBP superfamily domain
HMIECIIO_00421 0.0 pstC - - P ko:K02037,ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMIECIIO_00422 0.0 - - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMIECIIO_00423 4.85e-185 - 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMIECIIO_00424 3.97e-153 phoU - - P ko:K02039 - ko00000 negative regulation of phosphate transmembrane transport
HMIECIIO_00426 1.39e-281 - - - J - - - PFAM Endoribonuclease L-PSP
HMIECIIO_00427 0.0 - - - C - - - cytochrome C peroxidase
HMIECIIO_00428 0.0 - - - U - - - Involved in the tonB-independent uptake of proteins
HMIECIIO_00429 1.99e-19 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 COG0010 Arginase agmatinase formimionoglutamate hydrolase arginase family
HMIECIIO_00430 1.02e-296 - - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase family U32
HMIECIIO_00431 2.66e-147 - - - C - - - lactate oxidation
HMIECIIO_00432 0.0 - 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 DNA Topoisomerase IV
HMIECIIO_00433 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMIECIIO_00444 9.06e-44 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
HMIECIIO_00454 2.58e-69 - - - MP - - - regulation of cell-substrate adhesion
HMIECIIO_00457 2.03e-38 - - - L - - - Mu-like prophage protein gp29
HMIECIIO_00458 5.05e-130 - - - S - - - Glycosyl hydrolase 108
HMIECIIO_00465 1.49e-08 - - - - - - - -
HMIECIIO_00469 1.99e-138 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 DnaB-like helicase C terminal domain
HMIECIIO_00477 4.61e-55 - - - S - - - AAA domain
HMIECIIO_00481 9.41e-72 - - - KT - - - Peptidase S24-like
HMIECIIO_00488 2.58e-28 - - - L - - - Belongs to the 'phage' integrase family
HMIECIIO_00490 3.35e-116 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMIECIIO_00491 0.0 - - - S ko:K07037 - ko00000 7TM receptor with intracellular HD hydrolase
HMIECIIO_00492 1.22e-246 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMIECIIO_00493 2.73e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HMIECIIO_00494 4.98e-117 - - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HMIECIIO_00495 6.98e-80 - - - FG ko:K02503 - ko00000,ko04147 HIT domain
HMIECIIO_00496 3.6e-243 - 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMIECIIO_00497 3.81e-129 aroK 2.7.1.71 - E ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HMIECIIO_00498 9.56e-51 - - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Ribosomal protein S16
HMIECIIO_00501 1.6e-215 - - - L ko:K03733 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
HMIECIIO_00502 6.23e-184 - - - DTZ - - - EF-hand, calcium binding motif
HMIECIIO_00503 1.62e-65 - - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit
HMIECIIO_00504 5.68e-282 tgt 2.4.2.29 - J ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMIECIIO_00505 2.45e-150 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Putative methyltransferase
HMIECIIO_00506 4.32e-174 - - - F - - - NUDIX domain
HMIECIIO_00507 2.43e-126 - - - M ko:K03642 - ko00000 Lytic transglycolase
HMIECIIO_00508 1.91e-204 - 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HII
HMIECIIO_00509 1.9e-62 - - - L - - - bacterial (prokaryotic) histone like domain
HMIECIIO_00515 1.43e-142 - - - U ko:K03561 - ko00000,ko02000 MotA/TolQ/ExbB proton channel family
HMIECIIO_00516 3.02e-170 - 2.5.1.39 - H ko:K03179 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HMIECIIO_00517 2.73e-263 - 5.2.1.8 - O ko:K03771 - ko00000,ko01000,ko03110 SurA N-terminal domain
HMIECIIO_00518 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Domain of unknown function (DUF4982)
HMIECIIO_00519 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMIECIIO_00520 3.74e-204 - - - - - - - -
HMIECIIO_00521 6.79e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMIECIIO_00522 2.19e-56 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMIECIIO_00523 5.78e-35 - - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L29 protein
HMIECIIO_00524 3.42e-97 - - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMIECIIO_00525 4.27e-155 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMIECIIO_00526 4.97e-70 - - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
HMIECIIO_00527 4.05e-152 - - - - - - - -
HMIECIIO_00528 1.05e-58 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMIECIIO_00529 1.85e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMIECIIO_00530 8.72e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMIECIIO_00531 9.43e-132 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L4/L1 family
HMIECIIO_00532 3.86e-149 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMIECIIO_00533 3.67e-65 - - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S10p/S20e
HMIECIIO_00534 0.0 - - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMIECIIO_00535 2.91e-104 - - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S7p/S5e
HMIECIIO_00536 4.16e-85 - - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S12/S23
HMIECIIO_00537 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 BPG-independent PGAM N-terminus (iPGM_N)
HMIECIIO_00538 2.53e-97 - - - S ko:K07107 - ko00000,ko01000 Thioesterase superfamily
HMIECIIO_00539 1.82e-274 - - - T - - - PAS domain
HMIECIIO_00540 0.0 - - - T - - - Bacterial regulatory protein, Fis family
HMIECIIO_00541 0.0 - - - O - - - C-terminal four TMM region of protein-O-mannosyltransferase
HMIECIIO_00542 3.08e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease VII activity
HMIECIIO_00543 0.0 dxs 2.2.1.7 - HI ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMIECIIO_00544 3.99e-183 - - - S - - - Tetratricopeptide repeat
HMIECIIO_00545 2.31e-127 - - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Recombination protein O N terminal
HMIECIIO_00546 9.67e-251 - - - S ko:K07091 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Predicted permease YjgP/YjgQ family
HMIECIIO_00547 0.0 der - - S ko:K03977 - ko00000,ko03009 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
HMIECIIO_00548 1.24e-230 - - - EP ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
HMIECIIO_00550 1.78e-154 cat 2.3.1.28 - V ko:K19271 - br01600,ko00000,ko01000,ko01504 Chloramphenicol acetyltransferase
HMIECIIO_00552 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HMIECIIO_00553 2.88e-167 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMIECIIO_00554 0.0 - - - P ko:K02014 - ko00000,ko02000 TonB dependent receptor
HMIECIIO_00555 1.46e-204 - 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydrogenase
HMIECIIO_00557 0.0 - - - EGIP - - - Phosphate acyltransferases
HMIECIIO_00558 3.42e-111 - 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 Cytidine and deoxycytidylate deaminase zinc-binding region
HMIECIIO_00560 1.86e-94 - - - O - - - OsmC-like protein
HMIECIIO_00561 0.0 - - - CO - - - Disulphide bond corrector protein DsbC
HMIECIIO_00562 3.99e-176 - - - E - - - GDSL-like Lipase/Acylhydrolase
HMIECIIO_00563 2.75e-142 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Exonuclease
HMIECIIO_00564 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMIECIIO_00565 4.69e-79 rsfS - - S ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMIECIIO_00566 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMIECIIO_00568 2.13e-256 - - - S - - - AAA domain, putative AbiEii toxin, Type IV TA system
HMIECIIO_00569 1.25e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Enoyl-CoA hydratase/isomerase
HMIECIIO_00572 7.55e-302 - - - MU ko:K12340 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 efflux transmembrane transporter activity
HMIECIIO_00576 9.85e-147 - - - V - - - ATPases associated with a variety of cellular activities
HMIECIIO_00579 0.0 - - - V - - - ABC-2 type transporter
HMIECIIO_00580 8.38e-98 - - - - - - - -
HMIECIIO_00581 9e-192 - - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
HMIECIIO_00582 0.0 - - - S - - - Fungal chitosanase of glycosyl hydrolase group 75
HMIECIIO_00583 9.68e-221 - 2.5.1.21 - I ko:K00801 ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01006 Squalene/phytoene synthase
HMIECIIO_00584 0.0 - - - KT ko:K02584 ko02020,map02020 ko00000,ko00001,ko03000 Bacterial regulatory protein, Fis family
HMIECIIO_00585 0.0 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
HMIECIIO_00587 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 PFAM Glycoside hydrolase, family 20, catalytic core
HMIECIIO_00589 0.0 - - - - - - - -
HMIECIIO_00590 0.0 - 4.1.1.15 - E ko:K01580 ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Pyridoxal-dependent decarboxylase conserved domain
HMIECIIO_00592 5.21e-142 - - - J - - - Acetyltransferase (GNAT) domain
HMIECIIO_00593 0.0 - 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase alpha chain like domain
HMIECIIO_00594 1.22e-237 pyrD 1.3.5.2 - F ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroorotate dehydrogenase
HMIECIIO_00595 4.34e-152 - 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Thiamine monophosphate synthase
HMIECIIO_00596 1.1e-159 - - - K - - - Bacterial regulatory proteins, tetR family
HMIECIIO_00597 2.31e-164 - - - CO - - - Thioredoxin-like
HMIECIIO_00598 0.0 - - - C - - - Cytochrome c554 and c-prime
HMIECIIO_00599 1.88e-308 - - - S - - - PFAM CBS domain containing protein
HMIECIIO_00600 2.59e-312 tlyC - - S ko:K03699 - ko00000,ko02042 PFAM CBS domain containing protein
HMIECIIO_00601 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HMIECIIO_00602 3.01e-49 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal_S15
HMIECIIO_00603 8.11e-152 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HMIECIIO_00604 1.94e-212 - - - D ko:K19234,ko:K19236 ko01503,map01503 ko00000,ko00001,ko01002,ko01011 ErfK ybiS ycfS ynhG family protein
HMIECIIO_00605 0.0 - - - S - - - Terminase
HMIECIIO_00608 2.16e-200 - 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMIECIIO_00609 1.04e-144 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMIECIIO_00610 4.02e-167 - - - M - - - Peptidase family M23
HMIECIIO_00611 0.0 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 PFAM coagulation factor 5 8 type domain protein
HMIECIIO_00613 1.33e-174 - - - NU - - - Prepilin-type N-terminal cleavage methylation domain
HMIECIIO_00615 9.93e-180 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HMIECIIO_00616 0.0 - - - S - - - Type I phosphodiesterase / nucleotide pyrophosphatase
HMIECIIO_00617 0.0 - - - G - - - beta-N-acetylhexosaminidase activity
HMIECIIO_00618 6.94e-153 - 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 AAA domain
HMIECIIO_00620 4.86e-201 - - - S - - - DisA bacterial checkpoint controller nucleotide-binding
HMIECIIO_00621 2.97e-142 - - - - - - - -
HMIECIIO_00622 6.38e-151 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMIECIIO_00623 8.39e-197 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HMIECIIO_00624 1.48e-120 - - - M ko:K06142 - ko00000 Outer membrane protein (OmpH-like)
HMIECIIO_00625 2.31e-187 lpxD 2.3.1.191 - M ko:K02536 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HMIECIIO_00626 8.12e-195 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMIECIIO_00627 1.63e-189 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMIECIIO_00628 3.92e-247 - - - P ko:K02051 - ko00000,ko00002,ko02000 NMT1/THI5 like
HMIECIIO_00630 8.93e-223 hyl 2.3.1.48, 3.2.1.169, 3.2.1.35 GH84 G ko:K01197,ko:K15719 ko00531,ko01100,ko04931,map00531,map01100,map04931 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylhexosaminidase activity
HMIECIIO_00631 6.23e-118 - 3.1.3.82, 3.1.3.83 - E ko:K03273 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Polynucleotide kinase 3 phosphatase
HMIECIIO_00632 8.25e-131 - 5.3.1.28 - G ko:K03271 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 SIS domain
HMIECIIO_00633 0.0 - 2.7.1.167, 2.7.7.70 - M ko:K03272 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 pfkB family carbohydrate kinase
HMIECIIO_00634 1.06e-44 - - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S21
HMIECIIO_00635 3.01e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
HMIECIIO_00636 1.39e-258 - - - S - - - ankyrin repeats
HMIECIIO_00637 0.0 - - - EGP - - - Sugar (and other) transporter
HMIECIIO_00638 0.0 - - - - - - - -
HMIECIIO_00639 0.0 glnS 6.1.1.18 - J ko:K01886 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 tRNA synthetases class I (E and Q), anti-codon binding domain
HMIECIIO_00640 9.59e-288 - 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase II
HMIECIIO_00641 1.48e-104 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HMIECIIO_00642 4.7e-205 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMIECIIO_00643 1.1e-197 - - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 SRP54-type protein, GTPase domain
HMIECIIO_00644 1.07e-261 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Elongator protein 3, MiaB family, Radical SAM
HMIECIIO_00645 0.0 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 DnaB-like helicase C terminal domain
HMIECIIO_00646 3.76e-181 - - - U ko:K20276 ko02024,map02024 ko00000,ko00001 domain, Protein
HMIECIIO_00647 6.87e-153 - - - O - - - methyltransferase activity
HMIECIIO_00648 6.9e-288 - 3.5.1.42 - S ko:K03742 ko00760,map00760 ko00000,ko00001,ko01000 Competence-damaged protein
HMIECIIO_00649 0.0 - 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase, barrel domain
HMIECIIO_00650 1.07e-124 - - - K - - - Acetyltransferase (GNAT) domain
HMIECIIO_00654 1.99e-191 - - - E - - - haloacid dehalogenase-like hydrolase
HMIECIIO_00655 4.36e-142 - - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S4/S9 N-terminal domain
HMIECIIO_00656 2.11e-121 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMIECIIO_00657 1.11e-79 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMIECIIO_00658 3.9e-270 - 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Domain of unknown function (DUF1730)
HMIECIIO_00659 1.96e-223 - - - M ko:K07276 - ko00000 Mitochondrial fission ELM1
HMIECIIO_00660 2.1e-269 - - - M - - - Glycosyl transferase 4-like
HMIECIIO_00661 3.24e-271 - - - LU ko:K04096 - ko00000 DNA recombination-mediator protein A
HMIECIIO_00662 4.25e-219 - 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HMIECIIO_00663 5.5e-262 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMIECIIO_00664 4.93e-268 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Aminomethyltransferase folate-binding domain
HMIECIIO_00665 6.67e-86 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HMIECIIO_00666 0.0 gcvP 1.4.4.2 - E ko:K00281 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HMIECIIO_00668 6.98e-156 - - - L - - - Membrane
HMIECIIO_00669 0.0 - - - P ko:K01138 - ko00000,ko01000 PA14 domain
HMIECIIO_00670 0.0 - 3.6.4.13 - L ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DbpA RNA binding domain
HMIECIIO_00671 6.16e-176 - - - - - - - -
HMIECIIO_00672 0.0 - 3.1.1.53 - E ko:K05970 - ko00000,ko01000 Carbohydrate esterase, sialic acid-specific acetylesterase
HMIECIIO_00673 1.41e-242 - - - E - - - lipolytic protein G-D-S-L family
HMIECIIO_00674 1.84e-105 - - - S ko:K15977 - ko00000 DoxX
HMIECIIO_00675 4.07e-246 - 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 AIR synthase related protein, N-terminal domain
HMIECIIO_00676 0.0 - 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMIECIIO_00677 1.26e-139 - - - K ko:K03088 - ko00000,ko03021 ECF sigma factor
HMIECIIO_00679 2.34e-208 - - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
HMIECIIO_00680 1.31e-81 - - - DJ - - - Addiction module toxin, RelE StbE family
HMIECIIO_00681 8.37e-126 - 4.1.1.36 - H ko:K01598 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Flavoprotein
HMIECIIO_00683 2.31e-259 - - - M - - - Peptidase family M23
HMIECIIO_00684 0.0 - - - S - - - Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HMIECIIO_00685 0.0 - - - L - - - Polyphosphate kinase 2 (PPK2)
HMIECIIO_00686 2.48e-173 - - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
HMIECIIO_00687 1.94e-104 - - - K ko:K03826 - ko00000,ko01000 acetyltransferase
HMIECIIO_00688 9.7e-279 - 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
HMIECIIO_00689 8.3e-158 - 6.3.2.5 - H ko:K21977 ko00770,map00770 ko00000,ko00001,ko00002,ko01000 DNA / pantothenate metabolism flavoprotein
HMIECIIO_00690 1.67e-272 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMIECIIO_00691 5.45e-232 - - - S - - - Aspartyl protease
HMIECIIO_00692 4.79e-309 - 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 M ko:K02527 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
HMIECIIO_00693 2.75e-130 - - - L - - - Conserved hypothetical protein 95
HMIECIIO_00694 2.84e-211 - - - - - - - -
HMIECIIO_00696 4.28e-224 - - - S - - - Polyphosphate kinase 2 (PPK2)
HMIECIIO_00697 0.0 - - - - - - - -
HMIECIIO_00698 0.0 - - - M - - - Parallel beta-helix repeats
HMIECIIO_00700 6.18e-199 - - - S ko:K06889 - ko00000 alpha beta
HMIECIIO_00701 6.74e-106 - - - S ko:K06925 - ko00000,ko03016 Threonylcarbamoyl adenosine biosynthesis protein TsaE
HMIECIIO_00702 1.93e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal prokaryotic L21 protein
HMIECIIO_00703 2.14e-57 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L27 protein
HMIECIIO_00704 6.78e-100 - - - P ko:K09825 - ko00000,ko03000 Ferric uptake regulator family
HMIECIIO_00705 1.24e-179 - - - O ko:K09013 - ko00000,ko02000 ATPases associated with a variety of cellular activities
HMIECIIO_00706 0.0 - - - O ko:K09014 - ko00000 Uncharacterized protein family (UPF0051)
HMIECIIO_00707 9.06e-297 - - - O ko:K09015 - ko00000 Uncharacterized protein family (UPF0051)
HMIECIIO_00708 0.0 - - - M - - - Bacterial membrane protein, YfhO
HMIECIIO_00709 0.0 - - - P - - - Sulfatase
HMIECIIO_00710 2.93e-233 - 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Biotin and Thiamin Synthesis associated domain
HMIECIIO_00711 0.0 - 2.6.1.62 - H ko:K00833 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
HMIECIIO_00712 3.63e-135 - - - F - - - Bacteriocin-protection, YdeI or OmpD-Associated
HMIECIIO_00715 3.2e-76 - - - P ko:K03297,ko:K11741 - ko00000,ko02000 Multidrug Resistance protein
HMIECIIO_00716 1.08e-73 - - - P ko:K03297,ko:K11741 - ko00000,ko02000 Multidrug Resistance protein
HMIECIIO_00717 6.54e-221 - - - M - - - Glycosyl transferase family 2
HMIECIIO_00718 2.98e-115 flmH 2.3.1.57 - J ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMIECIIO_00719 2.94e-285 - 2.6.1.59 - M ko:K02805 - ko00000,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
HMIECIIO_00720 2.58e-276 - - - S - - - COGs COG4299 conserved
HMIECIIO_00721 7.66e-124 sprT - - K - - - SprT-like family
HMIECIIO_00722 1.38e-139 - - - - - - - -
HMIECIIO_00723 1.24e-90 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HMIECIIO_00724 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMIECIIO_00725 4.5e-201 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMIECIIO_00726 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMIECIIO_00727 6.46e-86 - - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 ATP synthase delta (OSCP) subunit
HMIECIIO_00728 4.38e-78 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 ATP synthase B/B' CF(0)
HMIECIIO_00729 1.65e-11 - - - S ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 PFAM H transporting two-sector ATPase C subunit
HMIECIIO_00730 6.27e-219 - - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 ATP synthase A chain
HMIECIIO_00731 0.0 - - - - - - - -
HMIECIIO_00732 0.0 - 3.4.16.4 - M ko:K05515 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein dimerisation domain
HMIECIIO_00733 3.16e-127 - - - S - - - L,D-transpeptidase catalytic domain
HMIECIIO_00734 3.11e-271 - - - S - - - COGs COG4299 conserved
HMIECIIO_00735 0.0 - - - G - - - Raffinose synthase or seed imbibition protein Sip1
HMIECIIO_00737 4.09e-218 - - - I - - - alpha/beta hydrolase fold
HMIECIIO_00738 8.29e-223 - - - - - - - -
HMIECIIO_00739 7.33e-110 - - - U - - - response to pH
HMIECIIO_00740 9.39e-183 - - - H - - - ThiF family
HMIECIIO_00741 1.18e-224 - 5.3.1.13 - M ko:K06041 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 SIS domain
HMIECIIO_00742 1.91e-192 - - - - - - - -
HMIECIIO_00743 2.76e-292 - 4.2.1.129, 5.4.99.17 - I ko:K06045 ko00909,ko01110,map00909,map01110 ko00000,ko00001,ko01000 PFAM Prenyltransferase squalene oxidase
HMIECIIO_00744 3.05e-109 - - - S ko:K15977 - ko00000 DoxX
HMIECIIO_00745 1.34e-201 - 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase, N-terminal
HMIECIIO_00746 2.46e-307 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMIECIIO_00747 1.25e-179 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMIECIIO_00748 0.0 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMIECIIO_00749 0.0 - - - K - - - Transcription elongation factor, N-terminal
HMIECIIO_00750 1.89e-166 - 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 SAICAR synthetase
HMIECIIO_00751 6.74e-117 - - - - - - - -
HMIECIIO_00752 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
HMIECIIO_00753 1.3e-177 - 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 CobB/CobQ-like glutamine amidotransferase domain
HMIECIIO_00755 2.24e-263 - - - G - - - M42 glutamyl aminopeptidase
HMIECIIO_00757 0.0 lacZ_17 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
HMIECIIO_00758 5.06e-236 - - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Actin
HMIECIIO_00759 0.0 - - - J ko:K08301 - ko00000,ko01000,ko03009,ko03019 Ribonuclease E/G family
HMIECIIO_00760 8.99e-277 - - - K - - - sequence-specific DNA binding
HMIECIIO_00761 1.28e-193 - - - - - - - -
HMIECIIO_00762 0.0 - - - S - - - Tetratricopeptide repeat
HMIECIIO_00764 4.52e-101 exbD2 - - U ko:K03559 - ko00000,ko02000 biopolymer transport protein
HMIECIIO_00765 1.65e-113 aglS - - U ko:K03559 - ko00000,ko02000 biopolymer transport protein
HMIECIIO_00766 9.91e-171 - - - U ko:K03561 - ko00000,ko02000 MotA/TolQ/ExbB proton channel family
HMIECIIO_00767 8.42e-149 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMIECIIO_00768 1.39e-157 - - - S - - - 3D domain
HMIECIIO_00769 5.64e-228 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil DNA glycosylase superfamily
HMIECIIO_00770 4.1e-178 - 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Indole-3-glycerol phosphate synthase
HMIECIIO_00772 4.83e-82 - - - L ko:K07460 - ko00000 Uncharacterised protein family UPF0102
HMIECIIO_00773 2.51e-151 - 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HII
HMIECIIO_00774 4.77e-310 - - - S - - - PFAM CBS domain containing protein
HMIECIIO_00775 8.43e-59 - - - S - - - Zinc ribbon domain
HMIECIIO_00776 2.79e-54 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMIECIIO_00778 2.9e-316 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Arginosuccinate synthase
HMIECIIO_00779 1.05e-115 - 3.1.6.8 - P ko:K01134 ko00600,ko04142,map00600,map04142 ko00000,ko00001,ko01000 COG3119 Arylsulfatase A
HMIECIIO_00780 8.12e-302 - 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 16S rRNA methyltransferase RsmB/F
HMIECIIO_00781 4.82e-178 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMIECIIO_00782 9.08e-165 - - - NU - - - Prokaryotic N-terminal methylation motif
HMIECIIO_00783 7.54e-143 - - - - - - - -
HMIECIIO_00784 0.0 - 3.1.6.1 - P ko:K01130 ko00140,ko00600,map00140,map00600 ko00000,ko00001,ko01000 Sulfatase
HMIECIIO_00788 2.03e-101 - - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
HMIECIIO_00789 1.19e-180 - - - S - - - competence protein
HMIECIIO_00790 2.92e-70 - - - - - - - -
HMIECIIO_00791 4.15e-191 - 3.6.1.66 - S ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 MazG nucleotide pyrophosphohydrolase domain
HMIECIIO_00792 3.68e-75 - - - - - - - -
HMIECIIO_00793 2.24e-264 - 3.1.13.5 - J ko:K03684 - ko00000,ko01000,ko03016 3'-5' exonuclease
HMIECIIO_00795 4.56e-139 - - - S ko:K07164 - ko00000 C4-type zinc ribbon domain
HMIECIIO_00796 2.22e-298 lpxK 2.7.1.130 - M ko:K00912 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
HMIECIIO_00797 0.0 - - - S ko:K07263 - ko00000,ko01000,ko01002 Insulinase (Peptidase family M16)
HMIECIIO_00798 5.63e-78 queH 1.17.99.6 - C ko:K09765 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HMIECIIO_00799 1.01e-151 - - - K - - - Psort location Cytoplasmic, score
HMIECIIO_00800 2.59e-134 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 5,10-methylenetetrahydrofolate reductase
HMIECIIO_00801 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HMIECIIO_00802 0.000103 - - - S - - - Entericidin EcnA/B family
HMIECIIO_00804 1.3e-206 - 1.4.1.16 - S ko:K03340 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HMIECIIO_00805 1.76e-175 - - - S - - - peptidoglycan biosynthetic process
HMIECIIO_00806 1.88e-136 - - - F - - - Bacteriocin-protection, YdeI or OmpD-Associated
HMIECIIO_00807 0.0 - - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 C-terminal, D2-small domain, of ClpB protein
HMIECIIO_00809 2.22e-231 - - - K - - - DNA-binding transcription factor activity
HMIECIIO_00810 2.5e-79 - - - S - - - PFAM Cupin 2 conserved barrel domain protein
HMIECIIO_00811 6.76e-131 - 3.6.3.12 - P ko:K01548 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HMIECIIO_00812 0.0 - 3.6.3.12 - P ko:K01547 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HMIECIIO_00813 0.0 - 3.6.3.12 - P ko:K01546 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HMIECIIO_00815 2.4e-167 - - - T ko:K07667 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HMIECIIO_00816 0.0 - 2.7.13.3 - T ko:K07646 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Osmosensitive K+ channel His kinase sensor domain
HMIECIIO_00818 5.7e-07 - - - - - - - -
HMIECIIO_00819 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Beta galactosidase small chain
HMIECIIO_00820 2.53e-266 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2219)
HMIECIIO_00821 1.78e-202 - - - L ko:K03424 - ko00000,ko01000 TatD related DNase
HMIECIIO_00822 2.63e-84 - - - M - - - Lysin motif
HMIECIIO_00823 8.74e-180 - - - S - - - L,D-transpeptidase catalytic domain
HMIECIIO_00824 0.0 - - - V - - - MatE
HMIECIIO_00825 1.05e-252 - 3.3.1.1 - H ko:K01251 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 adenosylhomocysteinase activity
HMIECIIO_00827 1.45e-258 - 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMIECIIO_00829 1.63e-156 - - - M - - - Bacterial transferase hexapeptide (six repeats)
HMIECIIO_00830 2.07e-262 - 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 RibD C-terminal domain
HMIECIIO_00831 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMIECIIO_00832 4.27e-273 - 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III, delta subunit
HMIECIIO_00833 0.0 - - - O - - - Trypsin
HMIECIIO_00834 1.18e-109 - 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
HMIECIIO_00835 0.0 - 3.6.4.13 - L ko:K03578 - ko00000,ko01000 Oligonucleotide/oligosaccharide-binding (OB)-fold
HMIECIIO_00836 3.52e-161 - - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
HMIECIIO_00837 0.0 - - - P - - - Cation transport protein
HMIECIIO_00838 8.16e-209 - - - S - - - Protein of unknown function (DUF1524)
HMIECIIO_00839 4.33e-17 - - - K - - - Helix-turn-helix domain
HMIECIIO_00841 2.58e-178 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMIECIIO_00842 0.0 - - - G - - - Domain of unknown function (DUF4091)
HMIECIIO_00843 3.2e-70 - - - K - - - HxlR-like helix-turn-helix
HMIECIIO_00844 1.32e-101 manC - - S - - - Cupin domain
HMIECIIO_00845 0.0 - 1.2.7.1 - C ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HMIECIIO_00846 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 tRNA synthetases class II (D, K and N)
HMIECIIO_00847 1.02e-187 pppL 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 protein serine/threonine phosphatase activity
HMIECIIO_00848 4.34e-152 - 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Glycerol-3-phosphate acyltransferase
HMIECIIO_00849 8.08e-236 gpsA 1.1.1.94 - C ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HMIECIIO_00850 8.62e-102 - - - - - - - -
HMIECIIO_00852 1.99e-263 pqqE - - C ko:K06139 - ko00000 SMART Elongator protein 3 MiaB NifB
HMIECIIO_00853 1.32e-313 pqqE - - C ko:K06139 - ko00000 SMART Elongator protein 3 MiaB NifB
HMIECIIO_00854 0.0 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
HMIECIIO_00855 4.94e-05 - - - - - - - -
HMIECIIO_00856 0.0 - - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI C-terminal
HMIECIIO_00857 2.36e-209 - - - S - - - Rhomboid family
HMIECIIO_00858 2.63e-269 - - - E - - - FAD dependent oxidoreductase
HMIECIIO_00859 2.64e-267 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HMIECIIO_00862 0.0 - - - S - - - Phosphoadenosine phosphosulfate reductase
HMIECIIO_00863 2e-120 - - - K - - - ParB domain protein nuclease
HMIECIIO_00866 9.17e-116 - - - L - - - Staphylococcal nuclease homologues
HMIECIIO_00867 5.62e-247 - - - M - - - Alginate lyase
HMIECIIO_00868 1.79e-206 - - - IQ - - - KR domain
HMIECIIO_00871 7.17e-104 yciA - - I ko:K10806 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 acyl-coa hydrolase
HMIECIIO_00872 1.42e-315 hsrA - - EGP - - - Major facilitator Superfamily
HMIECIIO_00873 1.72e-290 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HMIECIIO_00874 1.38e-241 - - - CH - - - D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HMIECIIO_00875 1.3e-180 - - - CH - - - D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HMIECIIO_00876 0.0 - 3.2.1.23 - G ko:K01190,ko:K12308 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolases family 35
HMIECIIO_00878 8.77e-158 - - - C - - - Nitroreductase family
HMIECIIO_00879 0.0 - - - E - - - Transglutaminase-like
HMIECIIO_00880 6.8e-111 - - - S - - - Bacterial transferase hexapeptide (six repeats)
HMIECIIO_00881 6.56e-112 - - - S ko:K08999 - ko00000 Bifunctional nuclease
HMIECIIO_00883 0.0 - - - P - - - Citrate transporter
HMIECIIO_00885 8.04e-258 - - - S - - - Glycosyltransferase family 10 (fucosyltransferase) C-term
HMIECIIO_00886 0.0 - - - I - - - Acyltransferase family
HMIECIIO_00887 1.74e-251 - - - S - - - Glycosyltransferase family 10 (fucosyltransferase) C-term
HMIECIIO_00888 7.13e-310 - - - M - - - Glycosyl transferases group 1
HMIECIIO_00889 1.03e-204 - - - - - - - -
HMIECIIO_00890 2.25e-287 - - - M - - - Glycosyltransferase like family 2
HMIECIIO_00891 2.26e-245 - 5.1.3.20 - M ko:K03274 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 3-beta hydroxysteroid dehydrogenase/isomerase family
HMIECIIO_00892 3.86e-235 - - GT9 M ko:K02843,ko:K02849 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 ADP-heptose-lipopolysaccharide heptosyltransferase activity
HMIECIIO_00893 6.79e-249 - - - S - - - Glycosyltransferase like family 2
HMIECIIO_00894 4.53e-244 - - - H - - - PFAM glycosyl transferase family 8
HMIECIIO_00895 4.39e-209 lpxG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase
HMIECIIO_00897 7.27e-242 - 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
HMIECIIO_00898 9.36e-171 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMIECIIO_00899 2.87e-219 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
HMIECIIO_00900 9e-65 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HMIECIIO_00901 8.9e-82 - - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
HMIECIIO_00902 1.15e-151 - - - NU - - - Prokaryotic N-terminal methylation motif
HMIECIIO_00903 6.87e-256 - 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HMIECIIO_00904 1.06e-127 - - - - - - - -
HMIECIIO_00905 1.02e-232 - - - S ko:K07088 - ko00000 Membrane transport protein
HMIECIIO_00906 2.89e-173 - - - S - - - NYN domain
HMIECIIO_00907 2.15e-151 ppaX_1 3.1.3.18, 3.6.1.1 - S ko:K01091,ko:K06019 ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 glycolate biosynthetic process
HMIECIIO_00908 1.58e-138 - - - S - - - Maltose acetyltransferase
HMIECIIO_00909 0.0 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 GMP synthase C terminal domain
HMIECIIO_00910 0.0 - 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 IMP dehydrogenase / GMP reductase domain
HMIECIIO_00911 1.43e-120 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Low molecular weight phosphatase family
HMIECIIO_00912 0.0 - - - M - - - PFAM YD repeat-containing protein
HMIECIIO_00914 5.94e-266 - - GT4 M ko:K16703 - ko00000,ko01000,ko01003 transferase activity, transferring glycosyl groups
HMIECIIO_00915 1.81e-253 - 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HMIECIIO_00916 8.14e-286 - - - S - - - Phosphotransferase enzyme family
HMIECIIO_00917 3.23e-253 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMIECIIO_00919 7.86e-138 - - - T - - - histone H2A K63-linked ubiquitination
HMIECIIO_00920 1.39e-130 - 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HMIECIIO_00921 5.11e-222 - - - G - - - Glycosyl hydrolases family 16
HMIECIIO_00922 8.55e-214 - 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HMIECIIO_00923 0.0 - - - T ko:K06207 - ko00000 Elongation factor G C-terminus
HMIECIIO_00924 1.32e-235 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
HMIECIIO_00925 3.97e-313 - 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-dependent decarboxylase, pyridoxal binding domain
HMIECIIO_00926 6.62e-257 - - - S ko:K11744 - ko00000 AI-2E family transporter
HMIECIIO_00927 1.98e-156 gph 3.1.3.18, 3.6.1.1 - S ko:K01091,ko:K06019 ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 glycolate biosynthetic process
HMIECIIO_00928 1.14e-294 - - - E - - - Amino acid permease
HMIECIIO_00929 2.02e-173 - 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Thiazole biosynthesis protein ThiG
HMIECIIO_00931 1.79e-201 - - - S - - - SigmaW regulon antibacterial
HMIECIIO_00932 7.86e-242 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HMIECIIO_00934 0.0 - - - P ko:K03455 - ko00000 TrkA-N domain
HMIECIIO_00935 0.0 - - - P - - - Dimerisation domain of Zinc Transporter
HMIECIIO_00936 5.84e-173 - - - K - - - Transcriptional regulator
HMIECIIO_00937 0.0 - - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HMIECIIO_00938 4.88e-169 - 4.3.99.3 - O ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HMIECIIO_00939 2.69e-181 - 2.7.13.3 - Q ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Transposase
HMIECIIO_00940 0.0 - 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HMIECIIO_00941 2.2e-313 - - - S - - - Protein of unknown function (DUF1015)
HMIECIIO_00942 7.38e-252 - - - E - - - Aminotransferase class-V
HMIECIIO_00943 5.45e-234 - - - S - - - Conserved hypothetical protein 698
HMIECIIO_00944 2.58e-214 - - - K - - - LysR substrate binding domain
HMIECIIO_00947 8.08e-287 - 3.2.1.23 - M ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HMIECIIO_00948 8.54e-295 - 3.2.1.23 - M ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HMIECIIO_00949 0.0 - - - I - - - PFAM Prenyltransferase squalene oxidase
HMIECIIO_00950 2.41e-301 - 4.2.1.129, 5.4.99.17, 5.5.1.16 - I ko:K06045,ko:K17811 ko00909,ko01110,map00909,map01110 ko00000,ko00001,ko01000 PFAM Prenyltransferase squalene oxidase
HMIECIIO_00951 1.98e-261 - - - M ko:K02022 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMIECIIO_00952 2.49e-157 - - - S - - - Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HMIECIIO_00954 5.12e-71 - - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin-like domain
HMIECIIO_00955 5.48e-296 - - - - - - - -
HMIECIIO_00956 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 tRNA synthetases class II (D, K and N)
HMIECIIO_00958 0.0 - - - T - - - pathogenesis
HMIECIIO_00959 0.0 - - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMIECIIO_00960 4.38e-113 ywrF - - S - - - FMN binding
HMIECIIO_00961 2.27e-86 - - - K - - - HxlR-like helix-turn-helix
HMIECIIO_00962 0.0 - 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 UvrD-like helicase C-terminal domain
HMIECIIO_00963 1.27e-305 - - - M - - - OmpA family
HMIECIIO_00964 0.0 - 6.3.2.45 - M ko:K02558 - ko00000,ko01000 Mur ligase family, catalytic domain
HMIECIIO_00965 6.55e-221 - - - E - - - Phosphoserine phosphatase
HMIECIIO_00966 6.31e-171 - - - S ko:K06861 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HMIECIIO_00969 2.72e-197 - 2.5.1.55 - M ko:K01627 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 DAHP synthetase I family
HMIECIIO_00970 1.86e-171 cbiX 4.99.1.3 - S ko:K03795 ko00860,ko01100,ko01120,map00860,map01100,map01120 ko00000,ko00001,ko01000 sirohydrochlorin cobaltochelatase activity
HMIECIIO_00971 5.88e-163 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S2
HMIECIIO_00972 2.05e-198 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMIECIIO_00973 7.6e-174 - - - E - - - ATPases associated with a variety of cellular activities
HMIECIIO_00975 7.19e-281 - 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 3-dehydroquinate synthase
HMIECIIO_00976 0.0 - - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
HMIECIIO_00977 0.0 - - - O - - - Trypsin
HMIECIIO_00978 4.99e-274 - - - - - - - -
HMIECIIO_00979 3.6e-145 - 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Aconitase C-terminal domain
HMIECIIO_00980 0.0 - 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Aconitase family (aconitate hydratase)
HMIECIIO_00981 7.14e-141 - 2.3.1.181 - H ko:K03801 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Biotin/lipoate A/B protein ligase family
HMIECIIO_00982 1.92e-238 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
HMIECIIO_00983 1.15e-238 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMIECIIO_00984 2.1e-215 - - - M ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 POTRA domain, FtsQ-type
HMIECIIO_00985 4.13e-228 ddl 6.3.2.4 - M ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 D-ala D-ala ligase N-terminus
HMIECIIO_00986 0.0 murB - - M - - - UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
HMIECIIO_00987 5.55e-267 - 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMIECIIO_00988 1.33e-277 - - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Cell cycle protein
HMIECIIO_00989 1e-160 mltD - CBM50 M ko:K08307,ko:K12204,ko:K19224 - ko00000,ko01000,ko01002,ko01011,ko02044 LysM domain
HMIECIIO_00990 1.45e-314 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMIECIIO_00991 8.1e-261 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMIECIIO_00992 0.0 - 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Mur ligase middle domain
HMIECIIO_00993 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMIECIIO_00994 0.0 - 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding Protein dimerisation domain
HMIECIIO_00996 0.0 rsmH 2.1.1.199 - M ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMIECIIO_00997 4.54e-105 - - - K ko:K03925 - ko00000 Belongs to the MraZ family
HMIECIIO_00998 5.27e-189 - - - S - - - Metallo-beta-lactamase superfamily
HMIECIIO_00999 2.82e-154 - - - S - - - UPF0126 domain
HMIECIIO_01000 3.95e-13 - - - S - - - Mac 1
HMIECIIO_01001 8.07e-314 mnmE - - J ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMIECIIO_01002 2.72e-263 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMIECIIO_01003 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase activity
HMIECIIO_01004 1.47e-208 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMIECIIO_01005 2.94e-184 - - - E - - - lipolytic protein G-D-S-L family
HMIECIIO_01006 1.04e-272 - - - S ko:K11941 - ko00000,ko01000 transferase activity, transferring acyl groups other than amino-acyl groups
HMIECIIO_01007 8.79e-143 - - - S - - - Hexapeptide repeat of succinyl-transferase
HMIECIIO_01008 1.64e-283 - - - M - - - Glycosyl transferases group 1
HMIECIIO_01009 6.99e-290 - - - M - - - transferase activity, transferring glycosyl groups
HMIECIIO_01010 0.0 - - - S - - - polysaccharide biosynthetic process
HMIECIIO_01012 1.36e-244 - - - H - - - PFAM glycosyl transferase family 8
HMIECIIO_01013 1.5e-254 - - - M - - - Glycosyl transferase, family 2
HMIECIIO_01014 1.98e-259 MA20_42350 2.7.8.12 - M ko:K09809 - ko00000,ko01000 Glycosyl transferase, family 2
HMIECIIO_01015 1.29e-282 - 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HMIECIIO_01016 9.5e-239 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMIECIIO_01017 5.47e-243 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMIECIIO_01020 1e-116 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
HMIECIIO_01021 1.43e-63 - - - L - - - PFAM Restriction endonuclease, type II, HindVP
HMIECIIO_01024 4.82e-25 - - - V - - - HNH endonuclease
HMIECIIO_01025 0.0 - - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
HMIECIIO_01026 1.19e-315 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 BNR/Asp-box repeat
HMIECIIO_01027 2.28e-79 - - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
HMIECIIO_01028 0.0 - 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 NAD synthase
HMIECIIO_01029 1.05e-79 - - - Q - - - methyltransferase activity
HMIECIIO_01030 7.99e-75 - - - Q - - - methyltransferase activity
HMIECIIO_01032 4.82e-137 - 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 Serine/threonine phosphatases, family 2C, catalytic domain
HMIECIIO_01033 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HMIECIIO_01034 6.13e-194 - - - - - - - -
HMIECIIO_01035 1.41e-120 - 3.2.2.28 - L ko:K03649 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 G/U mismatch-specific uracil-DNA glycosylase activity
HMIECIIO_01036 6.3e-224 - 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III, delta subunit
HMIECIIO_01037 2.88e-116 hisI 3.5.4.19 - E ko:K01496 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-AMP cyclohydrolase
HMIECIIO_01038 1.18e-170 - - - S ko:K05807 - ko00000,ko02000 Outer membrane lipoprotein
HMIECIIO_01039 7.51e-116 - - - S - - - Lipopolysaccharide-assembly
HMIECIIO_01040 1.19e-163 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Tetrapyrrole (Corrin/Porphyrin) Methylases
HMIECIIO_01041 3.77e-181 - - - S - - - Endonuclease/Exonuclease/phosphatase family
HMIECIIO_01042 2.72e-18 - - - - - - - -
HMIECIIO_01043 0.0 - - - P ko:K07221 - ko00000,ko02000 Phosphate-selective porin O and P
HMIECIIO_01044 2.4e-162 rnc 3.1.26.3 - K ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMIECIIO_01045 2.54e-39 - - - V - - - Abi-like protein
HMIECIIO_01046 3.15e-121 actI 1.5.1.36 - S ko:K00484 ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220 ko00000,ko00001,ko01000 FMN binding
HMIECIIO_01047 9.06e-259 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMIECIIO_01048 8.17e-147 - 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
HMIECIIO_01049 2.8e-143 - 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Cytidylate kinase
HMIECIIO_01050 0.0 - - - I - - - Acetyltransferase (GNAT) domain
HMIECIIO_01051 4.91e-209 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HMIECIIO_01052 1.77e-201 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HMIECIIO_01053 0.0 - - - GK - - - carbohydrate kinase activity
HMIECIIO_01054 0.0 - - - KLT - - - Protein tyrosine kinase
HMIECIIO_01056 2.66e-290 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMIECIIO_01057 1.37e-129 - - - D ko:K06287 - ko00000 Maf-like protein
HMIECIIO_01058 0.0 - 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
HMIECIIO_01070 2.55e-07 - - - - - - - -
HMIECIIO_01071 9.16e-95 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
HMIECIIO_01073 1.86e-114 - - - CO - - - cell redox homeostasis
HMIECIIO_01074 5.98e-72 - - - S - - - Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HMIECIIO_01075 6.22e-74 - - - S - - - Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HMIECIIO_01076 1.58e-117 - - - S - - - nitrogen fixation
HMIECIIO_01077 1.58e-148 dedA - - S - - - FtsZ-dependent cytokinesis
HMIECIIO_01078 2.36e-269 - 2.4.1.182 GT19 M ko:K00748 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HMIECIIO_01079 0.0 - 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
HMIECIIO_01080 7.09e-253 - - - L - - - Transposase IS200 like
HMIECIIO_01081 0.0 - - - P ko:K03281 - ko00000 Voltage gated chloride channel
HMIECIIO_01082 1.34e-109 ptsN 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770,ko:K02806 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
HMIECIIO_01085 1.59e-150 - - - - - - - -
HMIECIIO_01086 0.0 - - - E - - - lipolytic protein G-D-S-L family
HMIECIIO_01088 0.0 - - - MU ko:K18139 ko01501,ko02024,map01501,map02024 ko00000,ko00001,ko00002,ko01504,ko02000 Outer membrane efflux protein
HMIECIIO_01089 0.0 - - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HMIECIIO_01090 2.24e-282 - - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMIECIIO_01091 0.0 prlC 3.4.24.70 - E ko:K01414 - ko00000,ko01000,ko01002 Peptidase family M3
HMIECIIO_01092 0.0 - 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 LeuA allosteric (dimerisation) domain
HMIECIIO_01093 2.77e-41 - - - S - - - PurA ssDNA and RNA-binding protein
HMIECIIO_01094 2.49e-255 - - - D ko:K03593 - ko00000,ko03029,ko03036 Iron-sulfur cluster assembly protein
HMIECIIO_01095 0.0 - - - V ko:K03327 - ko00000,ko02000 MatE
HMIECIIO_01096 0.0 - - - V - - - T5orf172
HMIECIIO_01097 2.04e-198 - - - L - - - site-specific DNA-methyltransferase (adenine-specific) activity
HMIECIIO_01098 9.13e-63 - - - V - - - Type II restriction enzyme, methylase subunits
HMIECIIO_01099 6.33e-74 - - - L - - - Belongs to the 'phage' integrase family
HMIECIIO_01100 0.0 - 4.1.1.3 - C ko:K01571 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 HMGL-like
HMIECIIO_01101 0.0 - - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Phospholipase D. Active site motifs.
HMIECIIO_01102 5.77e-208 - 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Thymidylate synthase
HMIECIIO_01103 5.02e-115 - 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Dihydrofolate reductase
HMIECIIO_01104 0.0 - - - V - - - AcrB/AcrD/AcrF family
HMIECIIO_01105 4.2e-264 - - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Biotin-lipoyl like
HMIECIIO_01106 4.85e-107 - - - K - - - DNA-binding transcription factor activity
HMIECIIO_01108 1.53e-241 - 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase
HMIECIIO_01109 8.17e-159 - - - S - - - Metallo-beta-lactamase superfamily
HMIECIIO_01110 1.48e-291 - - - L - - - helicase superfamily c-terminal domain
HMIECIIO_01111 1.71e-110 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HMIECIIO_01112 4.02e-121 - - - - - - - -
HMIECIIO_01113 0.0 sepA - - Q - - - COG2015, Alkyl sulfatase and related hydrolases
HMIECIIO_01114 1.56e-113 - - - F ko:K08311 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 NUDIX domain
HMIECIIO_01115 2.43e-241 - - - E ko:K07588 - ko00000,ko01000 ArgK protein
HMIECIIO_01116 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycoside hydrolase, family 20, catalytic core
HMIECIIO_01117 2.36e-291 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycoside hydrolase, family 20, catalytic core
HMIECIIO_01119 4.27e-117 gepA - - K - - - Phage-associated protein
HMIECIIO_01120 1.15e-173 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HMIECIIO_01121 8.4e-136 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 - H ko:K00788,ko:K03147,ko:K14153 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HMIECIIO_01122 1.86e-214 - 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
HMIECIIO_01123 2.89e-310 - 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Cys/Met metabolism PLP-dependent enzyme
HMIECIIO_01124 2.55e-102 - - - K - - - Transcriptional regulator
HMIECIIO_01125 1.6e-272 - 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMIECIIO_01126 2.84e-173 - - - P ko:K10716 - ko00000,ko02000 domain protein
HMIECIIO_01127 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Hsp90 protein
HMIECIIO_01128 0.0 - - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
HMIECIIO_01129 1.35e-284 - - - P ko:K03449 - ko00000,ko02000 Major Facilitator Superfamily
HMIECIIO_01130 1.16e-240 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Aminoacyl tRNA synthetase class II, N-terminal domain
HMIECIIO_01131 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 B3/4 domain
HMIECIIO_01132 4.29e-256 - - - S - - - Domain of unknown function (DUF4105)
HMIECIIO_01133 1.66e-143 - - - M - - - Peptidoglycan-binding domain 1 protein
HMIECIIO_01134 0.0 - 4.1.99.1 - E ko:K01667 ko00380,map00380 ko00000,ko00001,ko01000 Beta-eliminating lyase
HMIECIIO_01135 1.03e-34 - - - KLT - - - Tyrosine-protein kinase, subgroup, catalytic domain
HMIECIIO_01136 1.14e-227 - - - S - - - Protein conserved in bacteria
HMIECIIO_01137 5.51e-211 - - - S - - - ABC-type transport system involved in multi-copper enzyme maturation permease component
HMIECIIO_01138 4.01e-160 - 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Methyladenine glycosylase
HMIECIIO_01139 7.03e-178 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Pyrroline-5-carboxylate reductase dimerisation
HMIECIIO_01142 6.75e-245 - - - I - - - PFAM Prenyltransferase squalene oxidase
HMIECIIO_01143 2.94e-131 - - - - - - - -
HMIECIIO_01144 0.0 - - - D - - - nuclear chromosome segregation
HMIECIIO_01145 0.0 - 5.4.99.2 - I ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Methylmalonyl-CoA mutase
HMIECIIO_01146 0.0 - 5.4.99.2 - I ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Methylmalonyl-CoA mutase
HMIECIIO_01149 4.45e-225 - 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
HMIECIIO_01150 2.72e-261 - - - S - - - COG0790 FOG TPR repeat, SEL1 subfamily
HMIECIIO_01151 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglucose isomerase
HMIECIIO_01152 0.0 - 2.7.9.1 - G ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Pyruvate phosphate dikinase, PEP/pyruvate binding domain
HMIECIIO_01153 1.22e-143 aat 2.3.2.6 - O ko:K00684 - ko00000,ko01000 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HMIECIIO_01154 1.62e-256 - - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 endonuclease III
HMIECIIO_01155 1.87e-218 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMIECIIO_01157 0.0 - 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HMIECIIO_01159 1.11e-180 - - - S - - - Integral membrane protein (intg_mem_TP0381)
HMIECIIO_01160 1.12e-116 agmK 1.8.1.8 - O ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 belongs to the thioredoxin family
HMIECIIO_01162 2.52e-281 - 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
HMIECIIO_01163 0.0 - 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
HMIECIIO_01165 2.34e-108 - - - S - - - Threonine/Serine exporter, ThrE
HMIECIIO_01166 4.75e-171 - - - S - - - Putative threonine/serine exporter
HMIECIIO_01167 0.0 - 2.1.1.13 - E ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 B12 binding domain
HMIECIIO_01168 2.15e-140 - - - Q - - - PA14
HMIECIIO_01171 1.33e-71 - - - - - - - -
HMIECIIO_01172 2.83e-93 - - - - - - - -
HMIECIIO_01173 0.0 mmyX 5.3.1.12 - F ko:K01812,ko:K07149,ko:K16139 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000,ko02000 Psort location Cytoplasmic, score
HMIECIIO_01174 8.23e-112 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Cys-tRNA(Pro) hydrolase activity
HMIECIIO_01176 4.32e-173 - 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Glutamine amidotransferase class-I
HMIECIIO_01177 7.35e-119 - - - T ko:K07005 - ko00000 pyridoxamine 5'-phosphate
HMIECIIO_01178 1.06e-47 - - - S - - - Integral membrane protein (intg_mem_TP0381)
HMIECIIO_01179 2.41e-99 - - - S - - - Integral membrane protein (intg_mem_TP0381)
HMIECIIO_01180 9.03e-270 - - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
HMIECIIO_01181 2e-148 - 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Peptidase C26
HMIECIIO_01182 2.45e-245 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 - EH ko:K01665,ko:K03342,ko:K13503,ko:K13950 ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HMIECIIO_01183 7.87e-150 - 4.1.3.38 - E ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 branched-chain-amino-acid transaminase activity
HMIECIIO_01184 1.64e-314 - 5.1.3.8 - G ko:K01787 ko00520,map00520 ko00000,ko00001,ko01000 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HMIECIIO_01185 1.38e-223 - 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Dihydrodipicolinate synthetase family
HMIECIIO_01186 0.0 - - - - - - - -
HMIECIIO_01187 2.65e-196 - - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HMIECIIO_01188 0.0 - - - D - - - Tetratricopeptide repeat
HMIECIIO_01189 1.53e-304 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HMIECIIO_01190 0.0 - 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminus
HMIECIIO_01191 2.52e-102 MA20_05485 - - S - - - Putative bacterial sensory transduction regulator
HMIECIIO_01192 1.12e-248 - - - M - - - HlyD family secretion protein
HMIECIIO_01193 0.0 - 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 Helix-hairpin-helix class 2 (Pol1 family) motifs
HMIECIIO_01194 1.82e-125 - 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Phosphoribosyl transferase domain
HMIECIIO_01196 6.48e-142 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HMIECIIO_01197 7.56e-246 - - - S - - - Imelysin
HMIECIIO_01198 0.0 - - - C - - - Di-haem oxidoreductase, putative peroxidase
HMIECIIO_01199 2.43e-264 - - - J - - - Endoribonuclease L-PSP
HMIECIIO_01200 4.39e-219 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 iron ion homeostasis
HMIECIIO_01201 2.03e-227 fatC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 iron ion homeostasis
HMIECIIO_01202 1.06e-180 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HMIECIIO_01203 2.42e-209 fatB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 iron ion transport
HMIECIIO_01204 2.69e-185 ccs1 - - O ko:K07399 - ko00000 cytochrome c biogenesis protein
HMIECIIO_01205 0.0 - - - O - - - Cytochrome C assembly protein
HMIECIIO_01206 2.52e-237 - - - S - - - Acyltransferase family
HMIECIIO_01207 0.0 - - - G - - - beta-N-acetylhexosaminidase activity
HMIECIIO_01208 4.58e-103 - - - S - - - Protein of unknown function (DUF721)
HMIECIIO_01209 4.64e-52 - - - C - - - 4Fe-4S single cluster domain of Ferredoxin I
HMIECIIO_01210 0.0 - - GT2 M ko:K03820 - ko00000,ko01000 Carbon-nitrogen hydrolase
HMIECIIO_01211 1.56e-176 - - - S - - - Phosphodiester glycosidase
HMIECIIO_01212 1.1e-228 - 2.7.7.13 - JM ko:K00966 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HMIECIIO_01213 0.0 fabZ 3.5.1.108, 4.2.1.59 - IM ko:K16363 ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
HMIECIIO_01214 1.75e-229 - - - G - - - pfkB family carbohydrate kinase
HMIECIIO_01215 2.1e-78 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMIECIIO_01216 8.55e-275 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
HMIECIIO_01220 9.16e-208 - - - L ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
HMIECIIO_01221 2.71e-269 - 2.1.1.72 - H ko:K07318 - ko00000,ko01000,ko02048 PFAM D12 class N6 adenine-specific DNA methyltransferase
HMIECIIO_01223 2.08e-240 BT0173 - - S - - - Psort location Cytoplasmic, score
HMIECIIO_01224 5.27e-170 BT0174 - - C ko:K04488 - ko00000 iron-sulfur transferase activity
HMIECIIO_01225 2.43e-201 lpxG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase
HMIECIIO_01227 2.38e-99 cysJ 1.8.1.2 - C ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 hydroxylamine reductase activity
HMIECIIO_01229 1.25e-261 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HMIECIIO_01230 1.33e-52 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMIECIIO_01231 4.73e-303 - 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HMIECIIO_01232 2.29e-315 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HMIECIIO_01233 1.28e-85 - - - S ko:K06940 - ko00000 Putative zinc- or iron-chelating domain
HMIECIIO_01236 2.05e-191 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Bacitracin resistance protein BacA
HMIECIIO_01237 7.46e-238 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HMIECIIO_01238 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMIECIIO_01239 0.0 kefA - - M ko:K05802,ko:K22051 - ko00000,ko02000 cellular water homeostasis
HMIECIIO_01240 1.78e-97 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 QueF-like protein
HMIECIIO_01241 1.02e-159 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Queuosine biosynthesis protein QueC
HMIECIIO_01242 4.51e-141 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMIECIIO_01243 0.0 - - - J - - - Beta-Casp domain
HMIECIIO_01244 1.23e-62 - - - S - - - Protein of unknown function (DUF1232)
HMIECIIO_01245 1.05e-160 - - - S - - - Protein of unknown function (DUF4230)
HMIECIIO_01246 4.25e-306 - 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate/isopropylmalate dehydrogenase
HMIECIIO_01247 1.6e-270 - - - S - - - Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HMIECIIO_01248 1.68e-61 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMIECIIO_01249 0.0 - - - C - - - Cytochrome c
HMIECIIO_01250 1.57e-298 - - - P - - - ABC-type Zn2 transport system, periplasmic component surface adhesin
HMIECIIO_01251 3.17e-157 - - - C - - - Cytochrome c
HMIECIIO_01253 9.16e-312 - - - C ko:K00185 - ko00000 Polysulphide reductase, NrfD
HMIECIIO_01254 1.22e-249 - 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 chorismate binding enzyme
HMIECIIO_01255 0.0 - 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolases family 31
HMIECIIO_01256 1.25e-315 - - - G - - - Glycosyl transferase 4-like domain
HMIECIIO_01257 1.22e-292 - 3.2.1.1 GH57 G ko:K07405 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 57
HMIECIIO_01258 8.02e-130 - 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMIECIIO_01259 1.28e-93 - - - U ko:K03559 - ko00000,ko02000 Biopolymer transport protein ExbD/TolR
HMIECIIO_01260 2.29e-136 - - - U ko:K03561 - ko00000,ko02000 MotA/TolQ/ExbB proton channel family
HMIECIIO_01261 5.53e-285 - 5.4.99.22 - M ko:K06178 - ko00000,ko01000,ko03009 translation initiation factor activity
HMIECIIO_01262 3.77e-118 - - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-strand binding protein family
HMIECIIO_01263 8.95e-316 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
HMIECIIO_01264 5.77e-145 - - - S ko:K09974 - ko00000 Domain of unknown function (DUF1287)
HMIECIIO_01265 0.0 fhs 6.3.4.3 - H ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Formate--tetrahydrofolate ligase
HMIECIIO_01266 9.98e-223 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Ketopantoate reductase PanE/ApbA C terminal
HMIECIIO_01267 1.65e-208 - - - S - - - Tetratricopeptide repeat
HMIECIIO_01268 1.4e-185 - - - T - - - Calcineurin-like phosphoesterase superfamily domain
HMIECIIO_01269 0.0 - - - EP ko:K13894 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMIECIIO_01270 0.0 - - - P ko:K13895 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMIECIIO_01271 0.0 - - - E ko:K13893 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HMIECIIO_01272 1.82e-229 - - - EP ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
HMIECIIO_01273 6.48e-244 - - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
HMIECIIO_01274 1.27e-273 - 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMIECIIO_01276 2.57e-120 - - - L - - - Protein of unknown function DUF262
HMIECIIO_01277 1.07e-208 - - - EG - - - EamA-like transporter family
HMIECIIO_01278 1.81e-282 - - - Q - - - Multicopper oxidase
HMIECIIO_01279 0.0 - 3.1.5.1 - F ko:K01129 ko00230,map00230 ko00000,ko00001,ko01000 Phosphohydrolase-associated domain
HMIECIIO_01280 3.71e-234 - - - O - - - Parallel beta-helix repeats
HMIECIIO_01281 1e-219 - - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
HMIECIIO_01283 1.07e-138 - - - K - - - ECF sigma factor
HMIECIIO_01284 1.08e-220 ytpP 2.7.1.180, 5.3.4.1 - CO ko:K01829,ko:K03671,ko:K03734,ko:K06196 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko02000,ko03110 cell redox homeostasis
HMIECIIO_01285 0.0 - 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 ThiC-associated domain
HMIECIIO_01286 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
HMIECIIO_01287 7.29e-60 csoR - - S ko:K21600 - ko00000,ko03000 negative regulation of transcription, DNA-templated
HMIECIIO_01288 2.34e-134 - - - K ko:K03088 - ko00000,ko03021 ECF sigma factor
HMIECIIO_01289 0.0 - 3.2.1.18 GH33 G ko:K01186 ko00511,ko00600,ko04142,map00511,map00600,map04142 ko00000,ko00001,ko01000,ko02042 N-terminal domain of BNR-repeat neuraminidase
HMIECIIO_01290 1.59e-121 - - - - - - - -
HMIECIIO_01291 0.0 - - - G - - - Major Facilitator Superfamily
HMIECIIO_01292 0.0 fucI 5.3.1.25, 5.3.1.3 - G ko:K01818 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Converts the aldose L-fucose into the corresponding ketose L-fuculose
HMIECIIO_01294 0.0 - 2.7.1.51 - G ko:K00879 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
HMIECIIO_01295 1.03e-201 - - - G - - - Class II Aldolase and Adducin N-terminal domain
HMIECIIO_01298 0.0 - - - V - - - MatE
HMIECIIO_01299 4.33e-161 menG 2.1.1.163, 2.1.1.201 - Q ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 ubiE/COQ5 methyltransferase family
HMIECIIO_01303 1.25e-199 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMIECIIO_01304 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMIECIIO_01305 1.65e-213 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMIECIIO_01306 3.95e-252 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMIECIIO_01308 7.09e-309 - - - E ko:K03310 - ko00000 Sodium:alanine symporter family
HMIECIIO_01309 2.43e-95 - - - K - - - -acetyltransferase
HMIECIIO_01310 1.43e-220 - 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Glutaminase
HMIECIIO_01311 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
HMIECIIO_01312 0.0 - - - M - - - PFAM YD repeat-containing protein
HMIECIIO_01313 3.12e-202 - - - M - - - PFAM YD repeat-containing protein
HMIECIIO_01316 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Prolyl-tRNA synthetase, C-terminal
HMIECIIO_01317 2.04e-158 - - - S - - - Peptidase family M50
HMIECIIO_01319 2.27e-215 - - - JM - - - Nucleotidyl transferase
HMIECIIO_01320 8.25e-273 - - - S - - - Phosphotransferase enzyme family
HMIECIIO_01321 1.01e-222 - 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 NmrA-like family
HMIECIIO_01323 0.0 - - - L ko:K07478 - ko00000 MgsA AAA+ ATPase C terminal
HMIECIIO_01324 1.38e-294 - - - - - - - -
HMIECIIO_01325 0.0 - - - - - - - -
HMIECIIO_01326 8.84e-140 mntP - - P - - - manganese ion transmembrane transporter activity
HMIECIIO_01328 4.17e-190 - - - S - - - Phenazine biosynthesis-like protein
HMIECIIO_01329 9.46e-176 - - - E - - - GDSL-like Lipase/Acylhydrolase
HMIECIIO_01330 8.94e-317 - - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, Activator interacting domain (AID)
HMIECIIO_01331 2.23e-272 ycaD - - EGP ko:K08219 - ko00000,ko02000 Major facilitator Superfamily
HMIECIIO_01332 1.49e-225 - 3.4.11.10, 3.4.11.6 - DZ ko:K19701 - ko00000,ko01000,ko01002 aminopeptidase activity
HMIECIIO_01333 5.73e-288 - - - G - - - Xylose isomerase domain protein TIM barrel
HMIECIIO_01334 0.0 - - - S - - - inositol 2-dehydrogenase activity
HMIECIIO_01336 5.78e-287 - 3.6.4.13 - L ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 helicase superfamily c-terminal domain
HMIECIIO_01338 1.03e-144 - 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 CDP-alcohol phosphatidyltransferase
HMIECIIO_01339 0.0 - 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMIECIIO_01340 0.0 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
HMIECIIO_01341 3.98e-277 - 4.2.1.51, 5.4.99.5 - E ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
HMIECIIO_01342 3.72e-237 - 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HMIECIIO_01343 1.57e-190 - - - S - - - NIF3 (NGG1p interacting factor 3)
HMIECIIO_01344 0.0 - - - S - - - Domain of unknown function (DUF4340)
HMIECIIO_01345 0.0 - - - N - - - ABC-type uncharacterized transport system
HMIECIIO_01346 2.49e-183 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HMIECIIO_01347 1.09e-223 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HMIECIIO_01348 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMIECIIO_01349 2.38e-133 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 nUDIX hydrolase
HMIECIIO_01351 4.06e-41 xerD1 - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
HMIECIIO_01352 2.73e-22 traC - - P - - - DNA integration
HMIECIIO_01353 8.13e-06 - - - L ko:K07505 - ko00000 Primase C terminal 2 (PriCT-2)
HMIECIIO_01355 9.34e-11 - - - - - - - -
HMIECIIO_01365 0.000452 - - - S - - - Putative phage abortive infection protein
HMIECIIO_01367 1.09e-12 - - - K ko:K07726 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HMIECIIO_01368 5.83e-30 - - - M - - - D-alanyl-D-alanine carboxypeptidase
HMIECIIO_01385 1.05e-19 - - - OU - - - Belongs to the peptidase S14 family
HMIECIIO_01388 2.82e-42 - - - S - - - Phage terminase large subunit (GpA)
HMIECIIO_01390 5e-252 - 2.3.1.1 - E ko:K14682 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetyltransferase (GNAT) family
HMIECIIO_01391 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMIECIIO_01392 0.0 - - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMIECIIO_01394 7.41e-177 - 6.3.5.11, 6.3.5.9 - V ko:K02224,ko:K18554 ko00860,ko01100,ko01120,map00860,map01100,map01120 br01600,ko00000,ko00001,ko01000,ko01504 Chloramphenicol phosphotransferase-like protein
HMIECIIO_01395 4.73e-85 - - - K ko:K07343 - ko00000 positive regulation of type IV pilus biogenesis
HMIECIIO_01396 9.41e-233 - - - CO - - - Redoxin
HMIECIIO_01397 1.73e-123 paiA - - K - - - acetyltransferase
HMIECIIO_01398 1.87e-215 - - - K - - - Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HMIECIIO_01400 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl tRNA synthetase N terminal dom
HMIECIIO_01403 0.0 - 3.4.24.70 - E ko:K01414 - ko00000,ko01000,ko01002 Peptidase family M3
HMIECIIO_01404 0.0 - - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HMIECIIO_01405 2.51e-06 - - - - - - - -
HMIECIIO_01406 0.0 - - - G - - - Glycosyl hydrolases family 18
HMIECIIO_01407 0.0 - - - S ko:K07126,ko:K13582 ko04112,map04112 ko00000,ko00001 beta-lactamase activity
HMIECIIO_01409 4.14e-279 - 6.2.1.26 - IQ ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 AMP-binding enzyme
HMIECIIO_01410 1.27e-70 - - - K - - - ribonuclease III activity
HMIECIIO_01411 1.14e-166 - - - - - - - -
HMIECIIO_01412 2.1e-140 nuoC 1.6.5.3 - C ko:K00332 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HMIECIIO_01413 6.52e-139 nuoB 1.6.5.3 - C ko:K00331 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HMIECIIO_01417 1.71e-101 - - - M - - - PFAM YD repeat-containing protein
HMIECIIO_01419 1.52e-146 - - - M - - - PFAM YD repeat-containing protein
HMIECIIO_01423 0.0 - - - M - - - pathogenesis
HMIECIIO_01425 3.72e-265 - - GT4 M ko:K16703 - ko00000,ko01000,ko01003 transferase activity, transferring glycosyl groups
HMIECIIO_01431 5.37e-148 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HMIECIIO_01434 0.0 - - - P - - - Cation transport protein
HMIECIIO_01435 3.53e-300 - - - V ko:K03327 - ko00000,ko02000 drug transmembrane transporter activity
HMIECIIO_01436 1.83e-120 - - - - - - - -
HMIECIIO_01437 9.86e-54 - - - - - - - -
HMIECIIO_01438 7.2e-103 - - - - - - - -
HMIECIIO_01439 0.0 - 2.1.1.182 - IJ ko:K02528 - ko00000,ko01000,ko03009 Ribosomal RNA adenine dimethylases
HMIECIIO_01440 1.26e-247 - 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 NmrA-like family
HMIECIIO_01441 0.0 - - - I - - - Prenyltransferase and squalene oxidase repeat
HMIECIIO_01442 0.0 - - - I - - - Prenyltransferase and squalene oxidase repeat
HMIECIIO_01443 6.39e-119 - - - T - - - STAS domain
HMIECIIO_01444 0.0 - - - S - - - Protein of unknown function (DUF2851)
HMIECIIO_01445 0.0 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65, N-terminal domain
HMIECIIO_01446 3.09e-290 - - - - - - - -
HMIECIIO_01447 0.0 - - - M - - - Sulfatase
HMIECIIO_01448 6.68e-286 - 4.1.99.19 - H ko:K03150 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Biotin and Thiamin Synthesis associated domain
HMIECIIO_01449 6.59e-205 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil DNA glycosylase superfamily
HMIECIIO_01450 4.71e-267 xerD1 - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
HMIECIIO_01451 0.0 - - - T - - - pathogenesis
HMIECIIO_01453 0.0 - 4.2.1.9 - EG ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Dehydratase family
HMIECIIO_01454 6.89e-168 - - - T ko:K07657 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HMIECIIO_01455 8.6e-291 - 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
HMIECIIO_01456 2.09e-10 - - - S - - - Mitochondrial domain of unknown function (DUF1713)
HMIECIIO_01457 2.25e-206 hisG 2.4.2.17 - E ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
HMIECIIO_01458 8.33e-314 - 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Aminopeptidase P, N-terminal domain
HMIECIIO_01459 2.82e-155 - - - S - - - Protein of unknown function (DUF3313)
HMIECIIO_01460 1.3e-263 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMIECIIO_01461 9.39e-256 - - - G - - - M42 glutamyl aminopeptidase
HMIECIIO_01462 2.8e-169 - - - - - - - -
HMIECIIO_01463 0.0 - - - NU - - - Type IV pilus assembly protein PilM;
HMIECIIO_01464 8.68e-208 - - - - - - - -
HMIECIIO_01465 2.27e-245 - - - - - - - -
HMIECIIO_01466 0.0 - - - NU ko:K02453 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 Bacterial type II and III secretion system protein
HMIECIIO_01467 1.85e-142 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMIECIIO_01468 0.0 - - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HMIECIIO_01469 0.0 - - - P - - - E1-E2 ATPase
HMIECIIO_01470 1.65e-240 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HMIECIIO_01471 1.1e-131 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMIECIIO_01472 5.44e-229 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HMIECIIO_01473 0.0 - 1.11.1.5 - P ko:K00428 - ko00000,ko01000 Di-haem cytochrome c peroxidase
HMIECIIO_01474 2.48e-40 feoA - - P ko:K04758 - ko00000,ko02000 iron ion homeostasis
HMIECIIO_01475 4.02e-48 feoA - - P ko:K04758 - ko00000,ko02000 iron ion homeostasis
HMIECIIO_01476 0.0 - - - P ko:K04759 - ko00000,ko02000 Ferrous iron transport protein B C terminus
HMIECIIO_01479 1.63e-302 - - - M ko:K07267 - ko00000,ko02000 wide pore channel activity
HMIECIIO_01481 0.0 - - - P - - - E1-E2 ATPase
HMIECIIO_01482 4.92e-90 - - - K - - - Helix-turn-helix diphteria tox regulatory element
HMIECIIO_01483 4.56e-206 - 3.1.1.53 - L ko:K03547,ko:K05970 - ko00000,ko01000,ko03400 3'-5' exonuclease activity
HMIECIIO_01484 2.86e-133 - 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 SpoU rRNA Methylase family
HMIECIIO_01485 0.0 - 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Fumarate reductase flavoprotein C-term
HMIECIIO_01486 1.62e-256 - - - S - - - Glycoside-hydrolase family GH114
HMIECIIO_01487 1.45e-299 - - - M - - - Glycosyl transferases group 1
HMIECIIO_01489 0.0 - 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 RecQ zinc-binding
HMIECIIO_01490 0.0 - - - P - - - Domain of unknown function (DUF4976)
HMIECIIO_01491 1.44e-225 - - - - - - - -
HMIECIIO_01492 0.0 - - - H - - - Flavin containing amine oxidoreductase
HMIECIIO_01493 1.87e-248 - - - - - - - -
HMIECIIO_01494 1.81e-251 rgpB - - M - - - transferase activity, transferring glycosyl groups
HMIECIIO_01495 0.0 ahcY 3.3.1.1 - H ko:K01251 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HMIECIIO_01496 3.77e-291 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMIECIIO_01497 1.66e-215 - - - KQ - - - Hypothetical methyltransferase
HMIECIIO_01500 0.0 - - - E - - - PFAM major facilitator superfamily MFS_1
HMIECIIO_01501 3.17e-206 - - - G ko:K06867,ko:K07001 - ko00000 response to abiotic stimulus
HMIECIIO_01503 3.69e-296 - - - MU ko:K15725 - ko00000,ko02000 efflux transmembrane transporter activity
HMIECIIO_01504 1.96e-297 czcB - - M ko:K15727 - ko00000,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMIECIIO_01505 0.0 - - - P ko:K07239 - ko00000 AcrB/AcrD/AcrF family
HMIECIIO_01506 1.46e-147 - - - K - - - Bacterial regulatory proteins, tetR family
HMIECIIO_01508 1.38e-168 - - - CO - - - Protein conserved in bacteria
HMIECIIO_01509 2.6e-231 - 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
HMIECIIO_01510 5.9e-156 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
HMIECIIO_01511 0.0 - - - M ko:K07277 - ko00000,ko02000,ko03029 Surface antigen
HMIECIIO_01512 8.38e-282 tig - - O ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMIECIIO_01513 2.5e-153 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMIECIIO_01514 0.0 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMIECIIO_01515 8.34e-255 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMIECIIO_01517 9.94e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMIECIIO_01519 3.61e-46 - - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 SecE/Sec61-gamma subunits of protein translocation complex
HMIECIIO_01520 6.29e-135 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
HMIECIIO_01521 2.58e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMIECIIO_01522 4.97e-156 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMIECIIO_01523 9.92e-110 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMIECIIO_01524 3.69e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMIECIIO_01526 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMIECIIO_01527 7.38e-17 - - - M - - - self proteolysis
HMIECIIO_01529 5.31e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMIECIIO_01530 1.67e-174 - - - S - - - Lysin motif
HMIECIIO_01531 3.5e-132 - - - - - - - -
HMIECIIO_01532 8.56e-45 acpP - - IQ ko:K02078 - ko00000,ko00001 Phosphopantetheine attachment site
HMIECIIO_01533 7.16e-174 coaX 2.7.1.33 - K ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Type III pantothenate kinase
HMIECIIO_01534 1.18e-273 - - - M - - - Monogalactosyldiacylglycerol (MGDG) synthase
HMIECIIO_01535 3.02e-227 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMIECIIO_01536 0.0 - 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 UvrD-like helicase C-terminal domain
HMIECIIO_01538 0.0 - - - S ko:K03307 - ko00000 Sodium:solute symporter family
HMIECIIO_01539 8.88e-284 - 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Galactokinase galactose-binding signature
HMIECIIO_01540 0.0 - - - M - - - Bacterial sugar transferase
HMIECIIO_01541 7.33e-143 - - - S - - - RNA recognition motif
HMIECIIO_01542 3.54e-185 - - - S - - - L,D-transpeptidase catalytic domain
HMIECIIO_01543 0.0 - - - - - - - -
HMIECIIO_01545 0.0 - - - V - - - ABC-2 type transporter
HMIECIIO_01546 0.0 - - - C - - - PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein
HMIECIIO_01547 3.3e-203 - - - S - - - Domain of unknown function (DUF362)
HMIECIIO_01548 1.49e-135 - - - J - - - Putative rRNA methylase
HMIECIIO_01549 2.86e-143 - 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMIECIIO_01550 3.73e-195 - 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease/Exonuclease/phosphatase family
HMIECIIO_01551 5.58e-289 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 NusA-like KH domain
HMIECIIO_01552 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMIECIIO_01553 2e-82 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMIECIIO_01554 0.0 - - - P - - - PA14 domain
HMIECIIO_01555 1.28e-15 - - - - - - - -
HMIECIIO_01556 8.65e-155 - - - - - - - -
HMIECIIO_01557 0.0 - - - T - - - 5TM C-terminal transporter carbon starvation CstA
HMIECIIO_01558 0.0 - - - EGIP - - - Phosphate acyltransferases
HMIECIIO_01559 8.17e-135 - 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMIECIIO_01560 4.34e-284 - 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMIECIIO_01561 3.78e-228 - - - C - - - e3 binding domain
HMIECIIO_01562 3.93e-128 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HMIECIIO_01563 8.81e-265 - - - S - - - PFAM glycosyl transferase family 2
HMIECIIO_01564 2.27e-290 - - - - - - - -
HMIECIIO_01565 3.16e-259 - - - S - - - Glycosyltransferase like family 2
HMIECIIO_01566 3.06e-226 - - - S - - - Glycosyl transferase family 11
HMIECIIO_01567 3.93e-272 - - GT2 S ko:K19427 - ko00000,ko01000 PFAM glycosyl transferase family 2
HMIECIIO_01569 1.19e-280 - - - H - - - PFAM glycosyl transferase family 8
HMIECIIO_01570 0.0 - 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Polyphosphate kinase middle domain
HMIECIIO_01571 0.0 - 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 Ppx/GppA phosphatase family
HMIECIIO_01572 2e-264 - - - S ko:K11941 - ko00000,ko01000 transferase activity, transferring acyl groups other than amino-acyl groups
HMIECIIO_01573 1.29e-192 map 3.4.11.18 - J ko:K01265 - ko00000,ko01000,ko01002 Metallopeptidase family M24
HMIECIIO_01574 6.41e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMIECIIO_01575 0.0 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMIECIIO_01577 6.42e-101 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
HMIECIIO_01578 3.38e-102 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMIECIIO_01579 2.38e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMIECIIO_01580 2.25e-105 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMIECIIO_01581 4.08e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMIECIIO_01582 5.36e-138 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMIECIIO_01583 1.53e-47 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal proteins 50S L24/mitochondrial 39S L24
HMIECIIO_01584 4.9e-207 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMIECIIO_01585 1.77e-124 - - - M ko:K03642 - ko00000 Lytic transglycolase
HMIECIIO_01586 0.0 - 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Calcineurin-like phosphoesterase
HMIECIIO_01587 0.0 - 2.7.11.1 - L ko:K08282 - ko00000,ko01000 SNF2 Helicase protein
HMIECIIO_01588 0.0 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HMIECIIO_01590 1.12e-288 - 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Mur ligase middle domain
HMIECIIO_01591 0.0 - - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Collagenase
HMIECIIO_01593 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMIECIIO_01594 6.52e-75 - - - L - - - Cupin 2, conserved barrel domain protein
HMIECIIO_01595 7.1e-130 - - - S - - - Cobalamin adenosyltransferase
HMIECIIO_01597 3.03e-296 - - - EGP - - - Major facilitator Superfamily
HMIECIIO_01598 4.75e-215 - - - K - - - LysR substrate binding domain
HMIECIIO_01599 1.17e-271 - - - S - - - tRNA-splicing ligase RtcB
HMIECIIO_01600 0.0 - - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 transmembrane transport
HMIECIIO_01602 2.51e-284 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMIECIIO_01604 2.57e-133 - - - D - - - ErfK ybiS ycfS ynhG family protein
HMIECIIO_01605 0.0 - 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Aconitase C-terminal domain
HMIECIIO_01606 8.8e-169 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 PFAM N-acetylmuramoyl-L-alanine amidase family 2
HMIECIIO_01610 0.0 - 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Bacterial DNA topoisomeraes I ATP-binding domain
HMIECIIO_01611 1.38e-90 - - - - - - - -
HMIECIIO_01612 0.0 - 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase HemD
HMIECIIO_01613 2.24e-101 - - - S - - - peptidase
HMIECIIO_01614 5.18e-172 - - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
HMIECIIO_01615 4.07e-97 - - - S - - - peptidase
HMIECIIO_01617 0.0 - - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 DNA Topoisomerase IV
HMIECIIO_01618 1.83e-74 - - - - - - - -
HMIECIIO_01620 1.91e-186 - - - E - - - GDSL-like Lipase/Acylhydrolase
HMIECIIO_01621 6.46e-312 - - - G - - - cellulose 1,4-beta-cellobiosidase activity
HMIECIIO_01622 1.13e-111 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HMIECIIO_01624 0.0 - - - P - - - Domain of unknown function
HMIECIIO_01625 1.7e-297 - - - S - - - AI-2E family transporter
HMIECIIO_01626 0.0 rseP 3.4.21.116 - M ko:K06399,ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 metalloendopeptidase activity
HMIECIIO_01627 2.11e-89 - - - - - - - -
HMIECIIO_01628 6.45e-268 - 3.5.3.12 - E ko:K10536 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Porphyromonas-type peptidyl-arginine deiminase
HMIECIIO_01629 0.0 - - - H ko:K07137 - ko00000 5-formyltetrahydrofolate cyclo-ligase activity
HMIECIIO_01631 3.73e-90 - 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 AIR carboxylase
HMIECIIO_01632 1.15e-122 - 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Phosphoribosyl transferase domain
HMIECIIO_01633 1.55e-222 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
HMIECIIO_01634 1.37e-306 - 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Dihydro-orotase-like
HMIECIIO_01635 2.51e-167 - - - S - - - Uncharacterised protein family UPF0066
HMIECIIO_01636 1.02e-94 - - - K - - - DNA-binding transcription factor activity
HMIECIIO_01637 8.54e-283 mtrC - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMIECIIO_01638 0.0 - - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HMIECIIO_01639 1.57e-284 - - - V - - - Beta-lactamase
HMIECIIO_01640 8.19e-316 - - - MU - - - Outer membrane efflux protein
HMIECIIO_01641 2.69e-310 - - - V - - - MacB-like periplasmic core domain
HMIECIIO_01642 2.12e-162 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMIECIIO_01643 4.09e-283 - - - M ko:K02005 - ko00000 HlyD family secretion protein
HMIECIIO_01645 5.75e-98 nudI 3.6.1.55 - F ko:K03574,ko:K12944 - ko00000,ko01000,ko03400 GDP-mannose mannosyl hydrolase activity
HMIECIIO_01646 6.23e-123 - - - S ko:K07095 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HMIECIIO_01647 1.65e-244 sun 2.1.1.176, 2.1.1.178 - J ko:K03500,ko:K11392 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMIECIIO_01648 5.9e-232 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HMIECIIO_01649 1.46e-118 - - - T - - - Prokaryotic dksA/traR C4-type zinc finger
HMIECIIO_01650 5.67e-33 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L33
HMIECIIO_01651 4.52e-49 - - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S18
HMIECIIO_01652 3.84e-189 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Type I GTP cyclohydrolase folE2
HMIECIIO_01653 1.02e-178 - - - S - - - Cytochrome C assembly protein
HMIECIIO_01654 3.58e-239 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Glutamyl-tRNAGlu reductase, N-terminal domain
HMIECIIO_01655 2.31e-232 - 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Porphobilinogen deaminase, dipyromethane cofactor binding domain
HMIECIIO_01657 8.67e-85 - - - S - - - Protein of unknown function, DUF488
HMIECIIO_01658 0.0 - - - M ko:K02847,ko:K13009,ko:K16705 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 -O-antigen
HMIECIIO_01659 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMIECIIO_01660 1.04e-54 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
HMIECIIO_01667 0.0 - - - S ko:K07126 - ko00000 beta-lactamase activity
HMIECIIO_01668 1.06e-182 - - - D ko:K03496 - ko00000,ko03036,ko04812 AAA domain
HMIECIIO_01669 0.0 - - - KLT - - - Sulfatase-modifying factor enzyme 1
HMIECIIO_01670 3.77e-289 kbl 2.3.1.29 - E ko:K00639 ko00260,map00260 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
HMIECIIO_01671 9.23e-124 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HMIECIIO_01672 1.17e-231 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HMIECIIO_01674 9.9e-121 - - - - - - - -
HMIECIIO_01675 5.86e-184 - - - H ko:K22132 - ko00000,ko03016 ThiF family
HMIECIIO_01676 1.45e-190 - - - S ko:K09769 - ko00000 YmdB-like protein
HMIECIIO_01677 1.56e-103 - - - T - - - Universal stress protein family
HMIECIIO_01678 2.41e-232 - 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 tRNA synthetases class I (W and Y)
HMIECIIO_01679 2.63e-206 - - - GM - - - Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HMIECIIO_01680 6.13e-165 - 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
HMIECIIO_01681 8.39e-89 - - - S ko:K09117 - ko00000 Yqey-like protein
HMIECIIO_01682 1.28e-223 - - - CO - - - amine dehydrogenase activity
HMIECIIO_01683 0.0 - 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 HMGL-like
HMIECIIO_01684 5.79e-214 - - - Q - - - Fumarylacetoacetate (FAA) hydrolase family
HMIECIIO_01685 6e-76 - - - P ko:K03972 - ko00000 Rhodanese Homology Domain
HMIECIIO_01686 0.0 - 3.2.1.50 - G ko:K01205 ko00531,ko01100,ko04142,map00531,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko04147 Alpha-L-fucosidase
HMIECIIO_01687 0.0 - - - O ko:K03696 ko01100,map01100 ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
HMIECIIO_01688 8.21e-246 - 2.7.14.1 - E ko:K19405 - ko00000,ko01000 ATP:guanido phosphotransferase, C-terminal catalytic domain
HMIECIIO_01689 4.49e-125 - - - S ko:K19411 - ko00000 UvrB/uvrC motif
HMIECIIO_01690 3.84e-180 - - - P ko:K09819 - ko00000,ko00002,ko02000 FecCD transport family
HMIECIIO_01691 2.15e-192 - - - P ko:K09820 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HMIECIIO_01692 2.03e-100 - - - - - - - -
HMIECIIO_01693 3.26e-226 - - - P ko:K02077 - ko00000,ko00002,ko02000 Zinc-uptake complex component A periplasmic
HMIECIIO_01694 0.0 hyl 2.3.1.48, 3.2.1.169, 3.2.1.35 GH84 G ko:K01197,ko:K15719 ko00531,ko01100,ko04931,map00531,map01100,map04931 ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042 beta-N-acetylhexosaminidase activity
HMIECIIO_01695 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 DHHA1 domain
HMIECIIO_01696 5.46e-22 - 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 HMGL-like
HMIECIIO_01701 5.98e-66 - - - M - - - PFAM YD repeat-containing protein
HMIECIIO_01707 5.88e-277 - - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
HMIECIIO_01708 9.19e-229 - - - O - - - Trypsin-like peptidase domain
HMIECIIO_01709 0.0 - 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Transglycosylase
HMIECIIO_01710 1.21e-285 - - - S ko:K09760 - ko00000 RmuC family
HMIECIIO_01711 5.69e-171 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD-hyrolase-like
HMIECIIO_01712 1.25e-132 - 2.3.1.129 - M ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 ko00000,ko00001,ko00002,ko01000,ko01005 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HMIECIIO_01713 7.56e-208 - - - S - - - RDD family
HMIECIIO_01714 0.0 - - - M ko:K09808 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 MacB-like periplasmic core domain
HMIECIIO_01715 1.38e-209 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HMIECIIO_01716 2.27e-90 - - - S ko:K09793 - ko00000 Protein of unknown function (DUF456)
HMIECIIO_01717 4.81e-58 - - - S - - - Psort location CytoplasmicMembrane, score
HMIECIIO_01718 0.0 - 3.2.1.51 GH95 G ko:K15923 ko00511,map00511 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65, N-terminal domain
HMIECIIO_01719 1.55e-258 - - - S - - - Peptidase family M28
HMIECIIO_01720 3.92e-246 - - - I - - - alpha/beta hydrolase fold
HMIECIIO_01721 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMIECIIO_01722 1.24e-186 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase (SPase) II
HMIECIIO_01723 6.88e-152 - - - S - - - Protein of unknown function (DUF1573)
HMIECIIO_01724 3.13e-114 - - - P - - - Rhodanese-like domain
HMIECIIO_01725 1.9e-298 - 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMIECIIO_01726 0.0 - - - S - - - acetyltransferases and hydrolases with the alpha beta hydrolase fold
HMIECIIO_01727 0.000231 - 2.7.11.1, 2.7.11.17 - T ko:K08794,ko:K13412,ko:K17530 ko04626,ko04921,ko04925,ko05145,map04626,map04921,map04925,map05145 ko00000,ko00001,ko01000,ko01001 protein serine/threonine kinase activity
HMIECIIO_01729 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMIECIIO_01730 0.0 - - - S - - - Tetratricopeptide repeat
HMIECIIO_01731 4.12e-100 - 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Glyoxalase-like domain
HMIECIIO_01732 0.0 - 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Carboxyl transferase domain
HMIECIIO_01734 6.88e-55 - - - I - - - PFAM biotin lipoyl attachment domain-containing protein
HMIECIIO_01735 0.0 - 4.1.1.3 - C ko:K01572 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Na+-transporting oxaloacetate decarboxylase beta subunit
HMIECIIO_01736 2.72e-191 - 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
HMIECIIO_01737 0.0 - - - C - - - Acetyl-CoA hydrolase/transferase C-terminal domain
HMIECIIO_01739 2.24e-204 - 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HMIECIIO_01740 7.56e-271 - 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Male sterility protein
HMIECIIO_01741 1.13e-228 - 2.7.1.11 - G ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Phosphofructokinase
HMIECIIO_01742 4.51e-182 - - - L ko:K10800 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 uracil-dna glycosylase
HMIECIIO_01744 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMIECIIO_01745 0.0 poxB 1.2.3.3, 1.2.5.1 - EH ko:K00156,ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Thiamine pyrophosphate enzyme, central domain
HMIECIIO_01746 0.000225 - - - - - - - -
HMIECIIO_01747 0.0 - - - G - - - alpha-galactosidase
HMIECIIO_01749 0.0 - 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
HMIECIIO_01750 1.53e-284 mtrC - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMIECIIO_01751 0.0 - - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HMIECIIO_01752 9.04e-317 - - - P ko:K14445 - ko00000,ko02000 Citrate transporter
HMIECIIO_01754 6.08e-178 - 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HMIECIIO_01756 7.63e-166 - - - S - - - PFAM Sel1 domain protein repeat-containing protein
HMIECIIO_01759 0.0 - - - L - - - DNA restriction-modification system
HMIECIIO_01762 3.92e-115 - - - - - - - -
HMIECIIO_01763 4.46e-182 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HMIECIIO_01765 5.46e-161 - 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMIECIIO_01766 5.91e-261 tdh 1.1.1.103 - E ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
HMIECIIO_01767 0.0 - 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Carbohydrate phosphorylase
HMIECIIO_01768 8.34e-180 - - - P ko:K10716 - ko00000,ko02000 domain protein
HMIECIIO_01769 1.55e-83 - 1.20.4.1 - P ko:K00537 - ko00000,ko01000 ArsC family
HMIECIIO_01770 0.0 - - - J ko:K07576 - ko00000 Beta-Casp domain
HMIECIIO_01771 8.48e-56 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HMIECIIO_01772 8.75e-240 - - - S - - - PFAM Sel1 domain protein repeat-containing protein
HMIECIIO_01774 2.75e-185 - 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 RNA pseudouridylate synthase
HMIECIIO_01775 2.05e-28 - - - - - - - -
HMIECIIO_01776 8.07e-174 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 tRNA (Guanine-1)-methyltransferase
HMIECIIO_01777 8.8e-239 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMIECIIO_01778 1.66e-87 - - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
HMIECIIO_01779 0.0 - - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
HMIECIIO_01780 8.55e-135 - - - C - - - Nitroreductase family
HMIECIIO_01781 1.75e-110 - - - S - - - Acetyltransferase (GNAT) family
HMIECIIO_01786 8.51e-210 - - - M - - - Peptidase family M23
HMIECIIO_01787 5.87e-228 - - - G - - - Xylose isomerase-like TIM barrel
HMIECIIO_01788 4.13e-183 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HMIECIIO_01789 4.21e-121 - 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HMIECIIO_01790 4.14e-175 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate reductase, N-terminus
HMIECIIO_01791 1.25e-204 dapA 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
HMIECIIO_01793 7.07e-249 - - - S ko:K11941 - ko00000,ko01000 transferase activity, transferring acyl groups other than amino-acyl groups
HMIECIIO_01794 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HMIECIIO_01798 5.93e-261 - 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
HMIECIIO_01799 8.43e-155 - 1.5.1.34 - C ko:K10679 ko00633,ko01120,map00633,map01120 ko00000,ko00001,ko01000 Nitroreductase family
HMIECIIO_01800 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, domain 2
HMIECIIO_01801 4.16e-178 - - - M - - - NLP P60 protein
HMIECIIO_01802 1.37e-86 - - - S ko:K09940 - ko00000 Domain of unknown function (DUF4870)
HMIECIIO_01804 8.53e-76 - - - C ko:K04651 - ko00000,ko03110 Hydrogenase/urease nickel incorporation, metallochaperone, hypA
HMIECIIO_01805 3.4e-126 - - - C ko:K03605 - ko00000,ko01000,ko01002 Hydrogenase maturation protease
HMIECIIO_01806 9.22e-290 hyaC - - C ko:K03620 ko02020,map02020 ko00000,ko00001 Prokaryotic cytochrome b561
HMIECIIO_01807 0.0 - 1.12.99.6 - C ko:K06281 ko00633,ko01120,map00633,map01120 ko00000,ko00001,ko01000 Nickel-dependent hydrogenase
HMIECIIO_01808 6.94e-298 - 1.12.99.6 - C ko:K06282 ko00633,ko01120,map00633,map01120 ko00000,ko00001,ko01000 NiFe/NiFeSe hydrogenase small subunit C-terminal
HMIECIIO_01809 0.0 - - - M ko:K07267 - ko00000,ko02000 wide pore channel activity
HMIECIIO_01811 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMIECIIO_01813 0.0 - - - H - - - Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMIECIIO_01814 0.0 - 3.4.24.3 - NU ko:K01387 - ko00000,ko01000,ko01002,ko02042 translation initiation factor activity
HMIECIIO_01815 0.0 - - - M - - - Transglycosylase
HMIECIIO_01816 2.63e-135 - 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 Peptidyl-tRNA hydrolase
HMIECIIO_01817 3.22e-215 - - - S - - - Protein of unknown function DUF58
HMIECIIO_01818 3.82e-231 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
HMIECIIO_01819 4.08e-215 - 3.5.1.53 - K ko:K12251 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
HMIECIIO_01821 5.79e-274 - - - E - - - Alcohol dehydrogenase GroES-like domain
HMIECIIO_01822 2.56e-309 - 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Seryl-tRNA synthetase N-terminal domain
HMIECIIO_01824 5.7e-241 - - - H - - - Elongator protein 3, MiaB family, Radical SAM
HMIECIIO_01825 0.0 yidC - - O ko:K03217,ko:K06872 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 serine-type endopeptidase activity
HMIECIIO_01826 1.07e-157 - - - S - - - L,D-transpeptidase catalytic domain
HMIECIIO_01827 2.76e-129 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMIECIIO_01828 3.55e-257 - 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
HMIECIIO_01829 5.92e-231 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G ko:K01186,ko:K12373,ko:K20830 ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko02042,ko03110 xyloglucan:xyloglucosyl transferase activity
HMIECIIO_01830 0.0 - - - I ko:K06889,ko:K09914 - ko00000 PFAM Prenyltransferase squalene oxidase
HMIECIIO_01831 9.53e-317 - 1.1.1.40 - C ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Malic enzyme, NAD binding domain
HMIECIIO_01833 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HMIECIIO_01834 0.0 - 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 tRNA synthetases class I (C) catalytic domain
HMIECIIO_01835 1.06e-300 - 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
HMIECIIO_01836 1.19e-92 - 5.1.3.29 - G ko:K02431 - ko00000,ko01000 RbsD / FucU transport protein family
HMIECIIO_01837 3.57e-283 - - - S - - - very-long-chain-acyl-CoA dehydrogenase activity
HMIECIIO_01839 0.0 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HMIECIIO_01840 3.66e-229 - - - C - - - Nitroreductase family
HMIECIIO_01841 0.0 - - - S - - - polysaccharide biosynthetic process
HMIECIIO_01842 8.91e-123 - - - C - - - NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HMIECIIO_01843 1.55e-39 - - - M - - - Glycosyltransferase, group 2 family protein
HMIECIIO_01844 6.44e-239 - - - M - - - Glycosyl transferase, family 2
HMIECIIO_01845 1.42e-209 - - - M - - - PFAM glycosyl transferase family 2
HMIECIIO_01846 5.38e-113 - - - S ko:K03818 - ko00000,ko01000 maltose O-acetyltransferase activity
HMIECIIO_01847 0.0 - - - - - - - -
HMIECIIO_01848 3.29e-279 lsgC - - M - - - transferase activity, transferring glycosyl groups
HMIECIIO_01849 5.46e-281 - - - M - - - Glycosyl transferase 4-like domain
HMIECIIO_01850 8.31e-253 - - - M - - - Glycosyl transferases group 1
HMIECIIO_01851 1.52e-201 - - - S - - - Glycosyl transferase family 11
HMIECIIO_01852 3.73e-263 - - - M ko:K02847,ko:K13009 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005,ko02000 -O-antigen
HMIECIIO_01853 3.46e-241 - - - - - - - -
HMIECIIO_01854 6.05e-295 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 transferase activity, transferring glycosyl groups
HMIECIIO_01855 2.84e-285 lsgC - - M - - - transferase activity, transferring glycosyl groups
HMIECIIO_01856 1.47e-292 lsgC - - M - - - transferase activity, transferring glycosyl groups
HMIECIIO_01857 1.2e-189 wbyL - GT2 M ko:K13002 - ko00000,ko01000,ko01003,ko01005 transferase activity, transferring glycosyl groups
HMIECIIO_01858 6.88e-176 - - - M - - - Bacterial sugar transferase
HMIECIIO_01859 9.48e-165 - 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 protein tyrosine phosphatase activity
HMIECIIO_01860 0.0 gumC - - DM ko:K16554 ko05111,map05111 ko00000,ko00001,ko02000 PFAM lipopolysaccharide biosynthesis protein
HMIECIIO_01861 5.68e-180 - - - M ko:K01991 ko02026,map02026 ko00000,ko00001,ko02000 polysaccharide export
HMIECIIO_01868 0.0 - - - G - - - Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain
HMIECIIO_01870 0.0 - - - S - - - OPT oligopeptide transporter protein
HMIECIIO_01871 5.46e-189 - 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
HMIECIIO_01873 0.0 - 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 DHHA2
HMIECIIO_01874 1.89e-253 - - - N ko:K18353 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01504 Endonuclease Exonuclease Phosphatase
HMIECIIO_01875 8.25e-63 - - - L ko:K09747 - ko00000 YbaB/EbfC DNA-binding family
HMIECIIO_01876 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMIECIIO_01878 4.03e-174 - - - D - - - Phage-related minor tail protein
HMIECIIO_01880 1.39e-173 - - - L ko:K03630 - ko00000 RadC-like JAB domain
HMIECIIO_01881 0.0 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMIECIIO_01882 1.07e-30 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMIECIIO_01883 2.79e-97 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMIECIIO_01884 1.67e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S9/S16
HMIECIIO_01885 1.27e-99 - 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Predicted SPOUT methyltransferase
HMIECIIO_01886 0.0 - - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMIECIIO_01887 6.34e-183 - - - U ko:K03561 - ko00000,ko02000 MotA/TolQ/ExbB proton channel family
HMIECIIO_01888 1.08e-97 - - - U ko:K03559 - ko00000,ko02000 Biopolymer transport protein ExbD/TolR
HMIECIIO_01889 0.0 - - - S - - - Tetratricopeptide repeat
HMIECIIO_01890 0.0 - - - M - - - PFAM glycosyl transferase family 51
HMIECIIO_01891 8.31e-186 - 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase family
HMIECIIO_01892 1.12e-116 ispF 4.6.1.12 - I ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HMIECIIO_01893 5.27e-181 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 PFAM N-acetylmuramoyl-L-alanine amidase family 2
HMIECIIO_01894 1.14e-227 - 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphomannose isomerase type I
HMIECIIO_01895 1.11e-236 - - - - - - - -
HMIECIIO_01896 4.15e-296 - - - C - - - Na+/H+ antiporter family
HMIECIIO_01897 2.53e-266 fcl 1.1.1.271 - GM ko:K02377 ko00051,ko00520,ko01100,map00051,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
HMIECIIO_01898 6.96e-265 - 4.2.1.47 - M ko:K01711 ko00051,ko00520,ko01100,map00051,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HMIECIIO_01899 2.56e-271 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase small chain, CPSase domain
HMIECIIO_01900 0.0 - 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HMIECIIO_01901 0.0 glnA 6.3.1.2 - S ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HMIECIIO_01902 0.0 - 1.4.1.13, 1.4.1.14 - E ko:K00265 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 GXGXG motif
HMIECIIO_01903 0.0 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
HMIECIIO_01904 8.98e-59 - - - S ko:K08998 - ko00000 Haemolytic
HMIECIIO_01905 4.9e-76 - 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 Ribonuclease P
HMIECIIO_01906 1.1e-34 - - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L34
HMIECIIO_01907 0.0 glnA 6.3.1.2 - S ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HMIECIIO_01908 0.0 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HMIECIIO_01909 0.0 - - - G - - - Trehalase
HMIECIIO_01910 2.45e-211 - 5.1.3.15 - G ko:K01792 ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Aldose 1-epimerase
HMIECIIO_01911 3.45e-157 - 1.4.3.5 - H ko:K00275 ko00750,ko01100,ko01120,map00750,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
HMIECIIO_01912 1.19e-199 - 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate phosphoribosyl transferase, N-terminal domain
HMIECIIO_01913 2.63e-208 - 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Polyprenyl synthetase
HMIECIIO_01914 9.55e-242 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMIECIIO_01916 5.5e-176 - - - - - - - -
HMIECIIO_01917 0.0 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase alpha chain
HMIECIIO_01918 1.02e-220 - 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Pyridine nucleotide-disulphide oxidoreductase
HMIECIIO_01919 1.96e-224 - - - E ko:K00612 - ko00000,ko01000 lipolytic protein G-D-S-L family
HMIECIIO_01920 1.33e-133 panZ - - K - - - -acetyltransferase
HMIECIIO_01925 1.2e-167 - - - L ko:K03424 - ko00000,ko01000 TatD related DNase
HMIECIIO_01926 0.0 - - - P ko:K03455 - ko00000 TrkA-N domain
HMIECIIO_01927 2.54e-208 - - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HMIECIIO_01928 8.59e-273 - - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
HMIECIIO_01929 5.35e-139 - 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMIECIIO_01930 1.05e-188 - 5.2.1.8 - O ko:K03773 - ko00000,ko01000,ko03110 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
HMIECIIO_01938 2.69e-256 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Iron-containing alcohol dehydrogenase
HMIECIIO_01940 0.0 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HMIECIIO_01941 2.16e-180 - - - C - - - Cytochrome c7 and related cytochrome c
HMIECIIO_01942 0.0 - - - C ko:K00184 - ko00000 4Fe-4S dicluster domain
HMIECIIO_01944 0.0 - 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 RecG wedge domain
HMIECIIO_01945 1.64e-165 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 PFAM N-acetylmuramoyl-L-alanine amidase family 2
HMIECIIO_01946 0.0 pckG 4.1.1.32 - C ko:K01596 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
HMIECIIO_01948 5.04e-82 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 4'-phosphopantetheinyl transferase superfamily
HMIECIIO_01949 1.62e-172 pdxJ 2.6.99.2 - H ko:K03474 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HMIECIIO_01950 0.0 - 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 AICARFT/IMPCHase bienzyme
HMIECIIO_01951 7.49e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L9, N-terminal domain
HMIECIIO_01952 1.05e-226 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HMIECIIO_01953 9.16e-209 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
HMIECIIO_01954 2.84e-18 - - - S - - - Lipocalin-like
HMIECIIO_01956 8.77e-239 cbiM - - P ko:K02007,ko:K02009,ko:K16915 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt ion transport
HMIECIIO_01957 1.99e-194 cbiQ - - P ko:K02007,ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transmembrane transporter activity
HMIECIIO_01958 4.82e-179 cbiO - - P ko:K02006,ko:K02008,ko:K16784,ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase activity
HMIECIIO_01959 0.0 - 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 HELICc2
HMIECIIO_01961 1.42e-209 ispE 2.7.1.148 - I ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
HMIECIIO_01962 0.0 - - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 TopoisomeraseII
HMIECIIO_01963 1.06e-173 - 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMIECIIO_01964 2.41e-259 - 2.7.7.13 - M ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HMIECIIO_01965 2.13e-96 - - - L ko:K07447 - ko00000,ko01000 Likely ribonuclease with RNase H fold.
HMIECIIO_01966 3.85e-235 - - - C - - - Zinc-binding dehydrogenase
HMIECIIO_01967 1.45e-55 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal L28 family
HMIECIIO_01968 1.04e-49 - - - - - - - -
HMIECIIO_01969 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Alpha galactosidase A
HMIECIIO_01970 1.84e-221 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMIECIIO_01971 0.0 - - - E - - - Aminotransferase class I and II
HMIECIIO_01972 4.6e-305 - 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMIECIIO_01973 1.04e-78 divIC - - D ko:K05589,ko:K13052 - ko00000,ko03036 cell cycle
HMIECIIO_01975 0.0 - - - P - - - Sulfatase
HMIECIIO_01977 9.64e-153 - - - K - - - Transcriptional regulator
HMIECIIO_01978 2.92e-189 - 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HMIECIIO_01979 1.35e-236 - 1.1.1.86 - E ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HMIECIIO_01980 1.03e-121 - - - M ko:K03098 - ko00000,ko04147 Lipocalin-like domain
HMIECIIO_01981 2.29e-208 - - - S ko:K07071 - ko00000 Domain of unknown function (DUF1731)
HMIECIIO_01982 3.48e-203 - - - O - - - stress-induced mitochondrial fusion
HMIECIIO_01984 4.01e-240 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HMIECIIO_01986 4.24e-296 - - - S ko:K07148 - ko00000 Protein of unknown function (DUF418)
HMIECIIO_01987 2.12e-237 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
HMIECIIO_01988 0.0 - - - - - - - -
HMIECIIO_01989 1.78e-241 - - - V - - - ATPases associated with a variety of cellular activities
HMIECIIO_01990 0.0 - - - S - - - ABC-type transport system involved in multi-copper enzyme maturation permease component
HMIECIIO_01991 1.58e-205 - - - S - - - Protein of unknown function DUF58
HMIECIIO_01992 0.0 - - - S - - - Aerotolerance regulator N-terminal
HMIECIIO_01993 0.0 - - - S - - - von Willebrand factor type A domain
HMIECIIO_01994 2.53e-293 - - - - - - - -
HMIECIIO_01995 4.05e-259 - 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Beta-eliminating lyase
HMIECIIO_01996 6.71e-90 - - - K - - - bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HMIECIIO_01997 2.81e-280 - - - C - - - Aldo/keto reductase family
HMIECIIO_01998 0.0 - - - KLT - - - Protein tyrosine kinase
HMIECIIO_01999 3.34e-139 - - - K ko:K03088 - ko00000,ko03021 DNA-templated transcription, initiation
HMIECIIO_02000 4.85e-195 - - - S - - - Metallo-beta-lactamase superfamily
HMIECIIO_02002 2.06e-232 - 2.7.11.1 - T ko:K08884,ko:K12132,ko:K20333 ko02024,map02024 ko00000,ko00001,ko01000,ko01001 PFAM Formylglycine-generating sulfatase enzyme
HMIECIIO_02003 3.88e-263 - 2.7.13.3 - T ko:K07646 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Osmosensitive K+ channel His kinase sensor domain
HMIECIIO_02005 2.54e-132 kdpC 3.6.3.12 - P ko:K01548 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HMIECIIO_02006 0.0 kdpB 3.6.3.12 - P ko:K01547 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HMIECIIO_02007 0.0 kdpA 3.6.3.12 - P ko:K01546 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HMIECIIO_02008 3.03e-65 - - - M - - - PFAM YD repeat-containing protein
HMIECIIO_02011 1.98e-129 - - - M - - - PFAM YD repeat-containing protein
HMIECIIO_02013 0.000102 - - - - - - - -
HMIECIIO_02016 0.0 - - - V ko:K18095 ko01501,ko02020,map01501,map02020 ko00000,ko00001,ko00002,ko01504,ko02000 AcrB/AcrD/AcrF family
HMIECIIO_02017 1.17e-241 - - - M ko:K18094 ko01501,ko02020,map01501,map02020 ko00000,ko00001,ko00002,ko01504,ko02000 Biotin-lipoyl like
HMIECIIO_02018 4.49e-191 - - - K - - - bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HMIECIIO_02019 1.13e-221 - 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HMIECIIO_02020 9.47e-236 - 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
HMIECIIO_02021 1.63e-298 - 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HMIECIIO_02022 3.32e-206 - - - S ko:K09949 - ko00000 Protein of unknown function (DUF1009)
HMIECIIO_02025 8.73e-87 - - - - - - - -
HMIECIIO_02026 5.6e-171 yyaQ - - V - - - Protein conserved in bacteria
HMIECIIO_02027 8.39e-191 - - - M - - - Glycosyl transferase WecB/TagA/CpsF family
HMIECIIO_02028 1.06e-189 - 3.1.4.55 - S ko:K06167 ko00440,map00440 ko00000,ko00001,ko01000 Metallo-beta-lactamase superfamily
HMIECIIO_02029 0.0 - - - L ko:K03631 - ko00000,ko03400 RecF/RecN/SMC N terminal domain
HMIECIIO_02030 0.0 - 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 E1-E2 ATPase
HMIECIIO_02031 2.85e-245 - - - G - - - Glycosyl hydrolases family 16
HMIECIIO_02032 9.29e-132 - - - J ko:K02356 - ko00000,ko03012 Elongation factor P (EF-P) OB domain
HMIECIIO_02033 1.2e-105 - - - S - - - ACT domain protein
HMIECIIO_02034 4.8e-313 - 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
HMIECIIO_02035 3.06e-85 - - - M ko:K03282 - ko00000,ko02000 Large-conductance mechanosensitive channel, MscL
HMIECIIO_02036 8.34e-277 - 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Alkaline phosphatase homologues
HMIECIIO_02037 4.93e-286 - - - EGP - - - Major facilitator Superfamily
HMIECIIO_02038 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycoside hydrolase, family 20, catalytic core
HMIECIIO_02039 2.54e-267 - - - G - - - M42 glutamyl aminopeptidase
HMIECIIO_02041 1.96e-121 ngr - - C - - - Rubrerythrin
HMIECIIO_02043 0.0 - - - S - - - Domain of unknown function (DUF1705)
HMIECIIO_02044 0.0 - - - M - - - Glycosyl Hydrolase Family 88
HMIECIIO_02045 0.0 - 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
HMIECIIO_02046 3.8e-43 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 CTP reductase activity
HMIECIIO_02047 1.52e-188 - 1.97.1.4 - O ko:K04069 - ko00000,ko01000 Radical SAM superfamily
HMIECIIO_02048 0.0 - - - P ko:K14445 - ko00000,ko02000 Citrate transporter
HMIECIIO_02049 0.0 - - - T - - - Histidine kinase
HMIECIIO_02050 1.33e-110 - - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
HMIECIIO_02051 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
HMIECIIO_02052 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
HMIECIIO_02053 7.36e-55 himA - - L ko:K03530,ko:K04764,ko:K05788 - ko00000,ko03032,ko03036,ko03400 regulation of translation
HMIECIIO_02054 0.0 - - - - - - - -
HMIECIIO_02057 6.96e-305 - 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 tRNA (Uracil-5-)-methyltransferase
HMIECIIO_02058 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HMIECIIO_02059 0.0 - - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein
HMIECIIO_02060 3.29e-258 - - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
HMIECIIO_02061 0.0 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
HMIECIIO_02062 4.2e-204 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HMIECIIO_02063 2.46e-307 - 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMIECIIO_02064 0.0 - - - - - - - -
HMIECIIO_02065 1.24e-163 - - - S - - - SWIM zinc finger
HMIECIIO_02066 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Argininosuccinate lyase C-terminal
HMIECIIO_02067 0.0 - - - U ko:K03321 - ko00000,ko02000 Sulfate permease family
HMIECIIO_02068 7.2e-125 - - - - - - - -
HMIECIIO_02069 1.04e-109 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMIECIIO_02070 0.0 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
HMIECIIO_02071 5.27e-184 - - - I - - - Acyl-ACP thioesterase
HMIECIIO_02072 5.99e-231 - 4.1.1.35 - M ko:K08678 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko00002,ko01000 3-beta hydroxysteroid dehydrogenase/isomerase family
HMIECIIO_02073 0.0 - - - T - - - His Kinase A (phosphoacceptor) domain
HMIECIIO_02074 2.04e-160 - - - T - - - Transcriptional regulatory protein, C terminal
HMIECIIO_02076 4.89e-237 - 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Delta-aminolevulinic acid dehydratase
HMIECIIO_02078 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMIECIIO_02079 3.29e-146 - - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMIECIIO_02081 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HMIECIIO_02082 8.71e-301 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HMIECIIO_02083 2.92e-163 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HMIECIIO_02084 6.63e-144 - - - L - - - Belongs to the 'phage' integrase family
HMIECIIO_02085 9.6e-79 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HMIECIIO_02086 4.43e-291 - - - S ko:K07148 - ko00000 Protein of unknown function (DUF418)
HMIECIIO_02087 1.28e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
HMIECIIO_02088 5.73e-120 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMIECIIO_02089 3.09e-61 - - - J - - - RF-1 domain
HMIECIIO_02090 1.67e-123 - - - - - - - -
HMIECIIO_02091 0.0 - 2.7.7.9 - G ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP--glucose-1-phosphate uridylyltransferase
HMIECIIO_02092 1.84e-183 - 2.1.1.144, 2.1.1.197 - FG ko:K00598,ko:K02169 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 trans-aconitate 2-methyltransferase activity
HMIECIIO_02094 2.33e-130 - - - S - - - protein trimerization
HMIECIIO_02095 2.54e-226 - - - M ko:K07271 - ko00000,ko01000 LICD family
HMIECIIO_02096 0.0 - 2.7.7.15 - H ko:K00968 ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231 ko00000,ko00001,ko00002,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
HMIECIIO_02097 2.13e-95 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
HMIECIIO_02098 0.0 cobD 2.6.1.9, 2.7.7.74, 4.1.1.81 - M ko:K00817,ko:K04720,ko:K07281 ko00340,ko00350,ko00360,ko00400,ko00401,ko00562,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00562,map00860,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 nucleotidyl transferase
HMIECIIO_02099 1.97e-260 - - - M ko:K07271 - ko00000,ko01000 LICD family
HMIECIIO_02100 0.0 - 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Alpha amylase, C-terminal all-beta domain
HMIECIIO_02102 5.06e-94 - - - S ko:K02426 - ko00000 Fe-S metabolism associated domain
HMIECIIO_02103 1.64e-223 - 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMIECIIO_02104 0.0 - - - P - - - Sulfatase
HMIECIIO_02105 0.0 - 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMIECIIO_02106 8.72e-53 - - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
HMIECIIO_02107 3.12e-223 hprK - - T ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
HMIECIIO_02108 0.0 - - - E - - - Peptidase dimerisation domain
HMIECIIO_02109 8.83e-209 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMIECIIO_02110 3.48e-140 - 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 5-formyltetrahydrofolate cyclo-ligase family
HMIECIIO_02111 0.0 - - - S - - - 50S ribosome-binding GTPase
HMIECIIO_02112 1.02e-163 - - - S ko:K06997 - ko00000 Alanine racemase, N-terminal domain
HMIECIIO_02113 1.88e-135 - - - K ko:K07735 - ko00000,ko03000 Uncharacterized ACR, COG1678
HMIECIIO_02114 3.67e-193 - - - S - - - L,D-transpeptidase catalytic domain
HMIECIIO_02115 0.0 - - - M - - - Glycosyl transferase family group 2
HMIECIIO_02116 7.47e-203 - - - - - - - -
HMIECIIO_02117 8.46e-84 - - - P ko:K06195 - ko00000 ApaG domain
HMIECIIO_02118 0.0 - - - L - - - SNF2 family N-terminal domain
HMIECIIO_02119 8.26e-106 - - - K - - - Lrp/AsnC ligand binding domain
HMIECIIO_02120 3.2e-286 - - - E ko:K10907 - ko00000,ko01000,ko01007 Cys/Met metabolism PLP-dependent enzyme
HMIECIIO_02121 9.2e-208 - - - S - - - CAAX protease self-immunity
HMIECIIO_02122 8.72e-155 - - - S - - - DUF218 domain
HMIECIIO_02123 0.0 - 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Anticodon binding domain
HMIECIIO_02124 1.36e-204 yeaE - - S - - - aldo-keto reductase (NADP) activity
HMIECIIO_02125 0.0 - - - S - - - Oxygen tolerance
HMIECIIO_02126 8.51e-42 - - - S ko:K07114 - ko00000,ko02000 von Willebrand factor (vWF) type A domain
HMIECIIO_02127 1.29e-187 - 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 2Fe-2S iron-sulfur cluster binding domain
HMIECIIO_02128 0.0 - 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 Fumarate reductase flavoprotein C-term
HMIECIIO_02129 4.83e-163 - - - - ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 -
HMIECIIO_02130 8.94e-56 - - - - - - - -
HMIECIIO_02131 1.43e-194 - - - S ko:K07051 - ko00000 TatD related DNase
HMIECIIO_02132 7.45e-49 XK27_09985 - - S - - - Protein of unknown function (DUF1232)
HMIECIIO_02134 1.15e-05 - - - - - - - -
HMIECIIO_02136 3.88e-308 - - - C - - - Sulfatase-modifying factor enzyme 1
HMIECIIO_02137 2.57e-170 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
HMIECIIO_02139 0.0 - - - S ko:K06158 - ko00000,ko03012 ABC transporter
HMIECIIO_02140 2.17e-08 - - - M - - - major outer membrane lipoprotein
HMIECIIO_02142 4.21e-137 - - - J ko:K05808 - ko00000,ko03009 Sigma 54 modulation/S30EA ribosomal protein C terminus
HMIECIIO_02144 9.61e-28 corC_1 - - P ko:K03699 - ko00000,ko02042 Transporter associated domain
HMIECIIO_02145 1.03e-159 - - - IQ - - - Short chain dehydrogenase
HMIECIIO_02146 1.67e-309 - - - C - - - Carboxymuconolactone decarboxylase family
HMIECIIO_02147 5.85e-275 - - - S ko:K06889 - ko00000 X-Pro dipeptidyl-peptidase (S15 family)
HMIECIIO_02148 2.06e-186 - - - S - - - Alpha/beta hydrolase family
HMIECIIO_02149 5.74e-176 - - - C - - - aldo keto reductase
HMIECIIO_02150 7.36e-220 - - - K - - - Transcriptional regulator
HMIECIIO_02151 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
HMIECIIO_02152 7.13e-301 - - - C - - - 4 iron, 4 sulfur cluster binding
HMIECIIO_02153 1.88e-111 - - - KT ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
HMIECIIO_02155 7.43e-174 - - - S - - - Protein of unknown function (DUF2589)
HMIECIIO_02156 1.61e-183 - - - - - - - -
HMIECIIO_02157 4.19e-133 - - - S - - - Protein of unknown function (DUF2589)
HMIECIIO_02158 1.2e-49 - - - - - - - -
HMIECIIO_02160 1.46e-75 - - - S ko:K09954 - ko00000 Putative quorum-sensing-regulated virulence factor
HMIECIIO_02161 5.94e-178 - 4.2.99.20 - I ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Alpha/beta hydrolase family
HMIECIIO_02162 1.39e-128 - - - U ko:K05595 - ko00000,ko02000 MarC family integral membrane protein
HMIECIIO_02166 3.56e-234 - - - E - - - PFAM lipolytic protein G-D-S-L family
HMIECIIO_02169 7.48e-188 - - - O ko:K04083 - ko00000,ko03110 Hsp33 protein
HMIECIIO_02170 3.62e-121 - 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMIECIIO_02171 0.0 - - - S ko:K06158 - ko00000,ko03012 ABC transporter
HMIECIIO_02172 9.28e-139 - - - - - - - -
HMIECIIO_02173 5.74e-211 ybfH - - EG - - - spore germination
HMIECIIO_02174 2.27e-75 - - - G - - - Cupin 2, conserved barrel domain protein
HMIECIIO_02175 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 tRNA synthetases class I (C) catalytic domain
HMIECIIO_02176 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycoside hydrolase, family 20, catalytic core
HMIECIIO_02177 0.0 - - - P - - - Domain of unknown function (DUF4976)
HMIECIIO_02178 9.83e-235 - - - CO - - - Thioredoxin-like
HMIECIIO_02180 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMIECIIO_02181 6.21e-39 - - - - - - - -
HMIECIIO_02182 0.0 - - - E - - - Sodium:solute symporter family
HMIECIIO_02183 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMIECIIO_02184 2.4e-180 kdsB 2.7.7.38 - M ko:K00979 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HMIECIIO_02185 0.0 - - - - - - - -
HMIECIIO_02187 3.36e-248 ppiD 5.2.1.8 - O ko:K03769,ko:K03770,ko:K03771,ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl cis-trans isomerase activity
HMIECIIO_02188 3.71e-260 - - - NU ko:K02669 - ko00000,ko02035,ko02044 Type II/IV secretion system protein
HMIECIIO_02189 5.1e-265 - - - NU ko:K02669 - ko00000,ko02035,ko02044 Type II/IV secretion system protein
HMIECIIO_02192 2.69e-38 - - - T - - - ribosome binding
HMIECIIO_02193 1.9e-231 - - - Q ko:K02067 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 MlaD protein
HMIECIIO_02194 1.75e-189 - - - Q ko:K02065 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
HMIECIIO_02195 1.49e-167 - - - Q ko:K02066 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Permease MlaE
HMIECIIO_02196 0.0 - - - H - - - NAD synthase
HMIECIIO_02197 0.0 - - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter transmembrane region
HMIECIIO_02198 0.0 - - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter transmembrane region
HMIECIIO_02199 0.0 - 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
HMIECIIO_02200 1.72e-147 - - - M - - - NLP P60 protein
HMIECIIO_02201 3.38e-294 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMIECIIO_02202 1.81e-310 - - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Tubulin/FtsZ family, GTPase domain
HMIECIIO_02205 3.02e-236 - - - S ko:K01128 - ko00000,ko01000 acid phosphatase activity
HMIECIIO_02206 4.57e-311 - 1.5.1.7 - E ko:K00290 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Saccharopine dehydrogenase C-terminal domain
HMIECIIO_02207 1.53e-219 - - - O - - - Thioredoxin-like domain
HMIECIIO_02208 0.0 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
HMIECIIO_02209 0.0 - - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HMIECIIO_02210 1.6e-217 - - - EP ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HMIECIIO_02211 1.87e-212 - - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
HMIECIIO_02212 1.01e-84 - - - S ko:K09922 - ko00000 Putative member of DMT superfamily (DUF486)
HMIECIIO_02214 4.56e-273 - 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 tRNA synthetases class I (W and Y)
HMIECIIO_02215 1.11e-235 - - - S ko:K14347 - ko00000,ko02000,ko04147 SBF-like CPA transporter family (DUF4137)
HMIECIIO_02218 0.0 - - - S - - - Large extracellular alpha-helical protein
HMIECIIO_02219 0.0 - - - M - - - Aerotolerance regulator N-terminal
HMIECIIO_02220 5.07e-235 - - - S - - - Peptidase family M28
HMIECIIO_02221 1.24e-200 - - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 ParB-like nuclease domain
HMIECIIO_02224 1.47e-97 - - - S - - - Glycosyl hydrolase 108
HMIECIIO_02234 1.4e-09 - - - S - - - Mu-like prophage I protein
HMIECIIO_02237 1.38e-76 - - - S - - - Mu-like prophage FluMu protein gp28
HMIECIIO_02241 1.98e-12 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HMIECIIO_02257 0.000705 - - - K - - - sequence-specific DNA binding
HMIECIIO_02258 8.31e-62 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
HMIECIIO_02259 0.0 - - - D ko:K03466 - ko00000,ko03036 Ftsk_gamma
HMIECIIO_02261 7.6e-145 - - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HMIECIIO_02262 1.08e-136 rbr - - C - - - Rubrerythrin
HMIECIIO_02263 0.0 - - - O - - - Cytochrome C assembly protein
HMIECIIO_02265 0.0 - 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Catalase
HMIECIIO_02266 1.17e-44 - - - S - - - R3H domain
HMIECIIO_02268 0.0 - 1.2.1.88, 1.5.5.2 - CE ko:K13821 ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko03000 Proline dehydrogenase
HMIECIIO_02269 1.79e-282 - - - S - - - Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HMIECIIO_02272 1.71e-64 - - - K - - - DNA-binding transcription factor activity
HMIECIIO_02273 9.88e-145 - - - - - - - -
HMIECIIO_02275 0.0 - - - S - - - Bacteriophage head to tail connecting protein
HMIECIIO_02277 1.56e-182 - - - - - - - -
HMIECIIO_02279 1.46e-72 - - - S - - - PFAM KAP P-loop domain protein
HMIECIIO_02289 2.46e-133 - - - S - - - Terminase
HMIECIIO_02290 5.05e-34 - - - S - - - Bacteriophage head to tail connecting protein
HMIECIIO_02299 3.45e-153 - - - - - - - -
HMIECIIO_02301 1.31e-38 - - - - - - - -
HMIECIIO_02307 1.78e-34 - - - - - - - -
HMIECIIO_02309 7.53e-96 - - - L - - - Transposase and inactivated derivatives
HMIECIIO_02310 7.2e-174 - - - - - - - -
HMIECIIO_02311 3.89e-209 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HMIECIIO_02312 2.18e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HMIECIIO_02313 3.12e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMIECIIO_02314 5.49e-206 - - - S ko:K03453 - ko00000 Bile acid
HMIECIIO_02317 6.39e-71 - - - - - - - -
HMIECIIO_02318 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMIECIIO_02319 0.0 - 2.3.1.40, 6.2.1.20 - IQ ko:K05939 ko00071,ko00564,map00071,map00564 ko00000,ko00001,ko01000 AMP-binding enzyme
HMIECIIO_02320 8.51e-50 - - - T - - - pathogenesis
HMIECIIO_02323 1.42e-215 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMIECIIO_02324 6.71e-285 - 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
HMIECIIO_02325 4.7e-57 - - - S ko:K06960 - ko00000 KH domain
HMIECIIO_02326 0.0 - - - - - - - -
HMIECIIO_02327 0.0 - 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 RNA cap guanine-N2 methyltransferase
HMIECIIO_02328 2.51e-215 - 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HMIECIIO_02329 5.51e-240 - 4.2.1.113 - M ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Mandelate Racemase Muconate Lactonizing
HMIECIIO_02330 0.0 - - - G - - - Glycosyl hydrolase family 20, domain 2
HMIECIIO_02332 0.0 - - - V - - - Polysaccharide biosynthesis C-terminal domain
HMIECIIO_02333 0.0 - 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
HMIECIIO_02334 1.89e-83 - - - G - - - single-species biofilm formation
HMIECIIO_02335 7.97e-113 - - - K ko:K13640 - ko00000,ko03000 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HMIECIIO_02336 4.8e-128 - - - S - - - Flavodoxin-like fold
HMIECIIO_02337 1.11e-188 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin domain
HMIECIIO_02338 8.08e-100 - - - S - - - Antibiotic biosynthesis monooxygenase
HMIECIIO_02339 1.66e-127 - - - C - - - FMN binding
HMIECIIO_02340 3.6e-265 - - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase
HMIECIIO_02341 1.48e-270 - - - C - - - Aldo/keto reductase family
HMIECIIO_02342 1.41e-266 - - - S ko:K06889 - ko00000 X-Pro dipeptidyl-peptidase (S15 family)
HMIECIIO_02343 1.3e-205 - - - S - - - Aldo/keto reductase family
HMIECIIO_02344 9.88e-239 - 1.2.7.3 - - ko:K00176,ko:K07138 ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200 br01601,ko00000,ko00001,ko00002,ko01000 -
HMIECIIO_02345 6.91e-302 - 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
HMIECIIO_02346 2.29e-141 - - - M - - - polygalacturonase activity
HMIECIIO_02348 2.07e-195 - - - KT - - - Peptidase S24-like
HMIECIIO_02349 6.03e-292 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HMIECIIO_02352 3.4e-178 - - - O - - - Trypsin
HMIECIIO_02353 5.49e-238 - - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
HMIECIIO_02354 6.2e-203 - - - - - - - -
HMIECIIO_02355 0.0 - - - S - - - Sulfatase-modifying factor enzyme 1
HMIECIIO_02356 1.85e-282 - - - S - - - Tetratricopeptide repeat
HMIECIIO_02359 2.63e-10 - - - - - - - -
HMIECIIO_02361 8.23e-62 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMIECIIO_02362 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMIECIIO_02363 2.48e-228 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
HMIECIIO_02364 4.38e-211 - - - S - - - Protein of unknown function DUF58
HMIECIIO_02365 8.06e-134 - - - - - - - -
HMIECIIO_02366 1.33e-228 - - - S - - - Protein of unknown function (DUF1194)
HMIECIIO_02368 0.0 - 4.2.1.2 - C ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
HMIECIIO_02370 2.53e-106 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
HMIECIIO_02372 0.0 - 3.2.1.52 GH20 G ko:K01207,ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko01501,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map01501,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycoside hydrolase, family 20, catalytic core
HMIECIIO_02373 1.85e-300 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMIECIIO_02374 3.4e-227 - 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Quinolinate synthetase A protein
HMIECIIO_02375 8.31e-254 - - - S - - - Putative S-adenosyl-L-methionine-dependent methyltransferase
HMIECIIO_02376 0.0 - - - S - - - pathogenesis
HMIECIIO_02377 0.0 - - - M - - - AsmA-like C-terminal region
HMIECIIO_02378 3.05e-170 - - - S ko:K06911 - ko00000 Pirin
HMIECIIO_02380 2.4e-172 - 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 FtsJ-like methyltransferase
HMIECIIO_02386 7.5e-25 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
HMIECIIO_02387 5.84e-28 - - - S ko:K19158 - ko00000,ko01000,ko02048 addiction module toxin, Txe YoeB family
HMIECIIO_02388 1.1e-50 - - - - - - - -
HMIECIIO_02389 1.6e-36 - - - - - - - -
HMIECIIO_02391 2.62e-189 - - - M - - - Psort location Cytoplasmic, score
HMIECIIO_02392 3.6e-49 - - - L - - - Transposase
HMIECIIO_02397 0.000158 - - - - - - - -
HMIECIIO_02407 2.07e-265 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
HMIECIIO_02408 1.15e-80 - - - S - - - Psort location Cytoplasmic, score
HMIECIIO_02409 2.46e-243 - - - K - - - ParB-like nuclease domain
HMIECIIO_02410 1.09e-66 - - - - - - - -
HMIECIIO_02413 2.61e-74 - - - - - - - -
HMIECIIO_02414 3.69e-189 - - - U - - - AAA domain
HMIECIIO_02415 1.18e-298 - - - L - - - PFAM Integrase catalytic
HMIECIIO_02416 2.44e-64 - - - - - - - -
HMIECIIO_02420 2.45e-150 - - - L - - - Psort location Cytoplasmic, score
HMIECIIO_02421 8.52e-245 - - - L - - - Protein of unknown function (DUF3991)
HMIECIIO_02422 2.51e-61 - - - - - - - -
HMIECIIO_02423 6.39e-170 - - - - - - - -
HMIECIIO_02424 4.61e-237 - - - S - - - COG NOG36404 non supervised orthologous group
HMIECIIO_02425 1.36e-46 - - - S - - - Domain of unknown function (DUF4315)
HMIECIIO_02426 4.82e-228 - - - M - - - NlpC p60 family protein
HMIECIIO_02427 1.71e-75 - - - - - - - -
HMIECIIO_02428 6.02e-171 - - - T - - - cheY-homologous receiver domain
HMIECIIO_02429 3.34e-232 - - - T - - - GHKL domain
HMIECIIO_02430 1.64e-17 - - - P ko:K05566 - ko00000,ko02000 Domain related to MnhB subunit of Na+/H+ antiporter
HMIECIIO_02431 4.31e-63 - - - P ko:K05567 - ko00000,ko02000 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
HMIECIIO_02432 4.84e-227 - - - CP ko:K05568,ko:K12141 - ko00000,ko01000,ko02000 PFAM NADH Ubiquinone plastoquinone (complex I)
HMIECIIO_02433 1.35e-169 - - - T - - - LytTr DNA-binding domain protein
HMIECIIO_02434 0.0 - - - T - - - GHKL domain
HMIECIIO_02435 1.77e-253 - - - S - - - Domain of unknown function (DUF4815)
HMIECIIO_02436 4.72e-67 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 COG COG3505 Type IV secretory pathway, VirD4 components
HMIECIIO_02437 2.67e-52 - - - S - - - Maff2 family
HMIECIIO_02438 2.75e-20 - - - - - - - -
HMIECIIO_02439 2.93e-200 - - - S - - - Psort location CytoplasmicMembrane, score
HMIECIIO_02440 6.26e-101 - - - D - - - SpoVG
HMIECIIO_02442 1.43e-220 - - - S - - - Domain of unknown function (DUF4316)
HMIECIIO_02443 6.17e-151 - - - S - - - Psort location Cytoplasmic, score
HMIECIIO_02444 1.74e-112 - - - - - - - -
HMIECIIO_02445 0.0 - - - L - - - Domain of unknown function (DUF4316)
HMIECIIO_02446 1.95e-43 - - - - - - - -
HMIECIIO_02447 1.78e-107 - - - S - - - PFAM Phage tail sheath protein
HMIECIIO_02449 8.57e-153 - - - - - - - -
HMIECIIO_02450 3.11e-69 - - - - - - - -
HMIECIIO_02453 1.54e-82 - - - S - - - Psort location Cytoplasmic, score
HMIECIIO_02454 0.0 - - - U - - - Psort location Cytoplasmic, score
HMIECIIO_02455 1.32e-86 - - - S - - - Cysteine-rich VLP
HMIECIIO_02456 0.0 - - - L - - - Domain of unknown function (DUF4368)
HMIECIIO_02457 1.01e-116 - - - L - - - Domain of unknown function (DUF4368)
HMIECIIO_02458 9.75e-237 - - - CP ko:K05565,ko:K05568 - ko00000,ko02000 NADH-Ubiquinone oxidoreductase (complex I), chain 5
HMIECIIO_02462 2.96e-105 - - - S - - - Domain of unknown function (DUF4316)
HMIECIIO_02463 1.06e-83 - - - - - - - -
HMIECIIO_02464 3.13e-270 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase
HMIECIIO_02465 1.58e-213 - - - S - - - competence protein
HMIECIIO_02466 4.53e-189 - - - L - - - Psort location Cytoplasmic, score
HMIECIIO_02467 0.0 - - - M - - - NlpC P60 family protein
HMIECIIO_02468 1.27e-46 - - - S - - - Domain of unknown function (DUF4315)
HMIECIIO_02469 7.94e-52 - - - S - - - Transposon-encoded protein TnpV
HMIECIIO_02473 8.82e-50 - - - S - - - Protein of unknown function (DUF3801)
HMIECIIO_02474 6.21e-109 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Type IV secretory system Conjugative DNA transfer
HMIECIIO_02475 4.57e-87 - - - - - - - -
HMIECIIO_02476 6.62e-105 - - - S - - - Protein of unknown function (DUF3801)
HMIECIIO_02477 1.63e-315 - - - M - - - NlpC p60 family protein
HMIECIIO_02478 2.43e-109 - - - L - - - Transposase DDE domain
HMIECIIO_02480 4.37e-43 - - - - - - - -
HMIECIIO_02481 1.3e-109 - - - S - - - Domain of unknown function (DUF3846)
HMIECIIO_02482 1.14e-229 - - - S - - - Replication initiator protein A (RepA) N-terminus
HMIECIIO_02483 1.07e-39 - - - L - - - Transposase
HMIECIIO_02484 2.01e-81 - - - S - - - Protein of unknown function (DUF3851)
HMIECIIO_02485 1.65e-110 - - - D - - - MobA MobL family protein
HMIECIIO_02486 1.34e-117 - - - L - - - CHC2 zinc finger domain protein
HMIECIIO_02488 1.97e-114 - - - L - - - Protein of unknown function (DUF3849)
HMIECIIO_02489 2.38e-56 - - - - - - - -
HMIECIIO_02490 1.31e-75 - - - S - - - Bacterial mobilisation protein (MobC)
HMIECIIO_02491 2.6e-121 - - - - - - - -
HMIECIIO_02495 2.08e-133 - - - L - - - Transposase domain (DUF772)
HMIECIIO_02503 5.92e-86 - - - S - - - Protein of unknown function (DUF3801)
HMIECIIO_02504 2.04e-193 - - - L - - - Psort location Cytoplasmic, score
HMIECIIO_02505 0.0 - - - U - - - Psort location Cytoplasmic, score
HMIECIIO_02509 1.61e-137 - - - L - - - Phage integrase family
HMIECIIO_02510 6.72e-245 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
HMIECIIO_02511 9.53e-98 - - - U - - - Psort location Cytoplasmic, score 8.87
HMIECIIO_02513 6.52e-37 - - - L ko:K07491 - ko00000 Protein involved in DNA binding, transposase activity and transposition DNA-mediated
HMIECIIO_02514 2e-32 - - - - - - - -
HMIECIIO_02515 1.04e-83 - - - O ko:K03697 - ko00000,ko03110 Bacterial TniB protein
HMIECIIO_02518 1.43e-95 - - - S - - - PrgI family protein
HMIECIIO_02519 2.27e-40 - - - S - - - Domain of unknown function (DUF4366)
HMIECIIO_02520 2.68e-43 - - - - - - - -
HMIECIIO_02521 9.02e-163 - - - S - - - Psort location Cytoplasmic, score
HMIECIIO_02524 1.78e-14 - - - - - - - -
HMIECIIO_02526 1.25e-111 - - - L - - - Psort location Cytoplasmic, score 7.50

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)