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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
FICKLOND_00001	3.91e-289	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
FICKLOND_00002	0.0	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	thiolester hydrolase activity
FICKLOND_00003	2.33e-281	-	-	-	IQ	-	-	-	Beta-ketoacyl synthase, C-terminal domain
FICKLOND_00004	6.65e-261	-	2.3.1.47	-	H	ko:K00652	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
FICKLOND_00008	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FICKLOND_00009	7.37e-311	-	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
FICKLOND_00010	1.44e-175	hypB	-	-	KO	ko:K04652	-	ko00000,ko03110	CobW/HypB/UreG, nucleotide-binding domain
FICKLOND_00011	0.0	-	-	-	O	ko:K04656	-	ko00000	HypF finger
FICKLOND_00012	2.74e-50	-	-	-	O	ko:K04653	-	ko00000	HupF/HypC family
FICKLOND_00013	1.11e-261	-	-	-	O	ko:K04654	-	ko00000	Hydrogenase formation hypA family
FICKLOND_00014	5.1e-241	-	-	-	O	ko:K04655	-	ko00000	AIR synthase related protein, N-terminal domain
FICKLOND_00015	1.14e-279	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
FICKLOND_00016	0.0	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
FICKLOND_00017	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	MreB/Mbl protein
FICKLOND_00018	2.2e-61	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FICKLOND_00019	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
FICKLOND_00020	5.31e-99	-	-	-	S	-	-	-	peptidase
FICKLOND_00021	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
FICKLOND_00025	8.04e-298	-	-	-	-	-	-	-	-
FICKLOND_00026	0.0	-	-	-	D	-	-	-	Chain length determinant protein
FICKLOND_00027	9.65e-133	-	-	-	M	-	-	-	Polysaccharide biosynthesis/export protein
FICKLOND_00029	4.46e-148	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
FICKLOND_00030	1.67e-249	-	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
FICKLOND_00031	3.33e-285	pgk	2.7.2.3	-	G	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
FICKLOND_00032	3.67e-236	-	-	-	-	-	-	-	-
FICKLOND_00033	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	myo-inosose-2 dehydratase activity
FICKLOND_00034	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
FICKLOND_00035	0.0	-	-	-	L	-	-	-	TRCF
FICKLOND_00036	2.29e-296	-	-	-	-	-	-	-	-
FICKLOND_00037	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
FICKLOND_00038	3e-254	-	-	-	S	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FICKLOND_00040	5.56e-214	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	PHP domain
FICKLOND_00041	1.4e-259	-	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphate acetyl/butaryl transferase
FICKLOND_00042	1.16e-241	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
FICKLOND_00043	2.59e-75	-	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
FICKLOND_00047	1.33e-100	-	-	-	MP	-	-	-	regulation of cell-substrate adhesion
FICKLOND_00051	0.0	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
FICKLOND_00052	1.83e-231	-	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
FICKLOND_00053	0.0	-	-	-	G	-	-	-	Glycogen debranching enzyme
FICKLOND_00054	0.0	-	-	-	M	-	-	-	NPCBM/NEW2 domain
FICKLOND_00055	0.0	-	-	-	M	ko:K04744	-	ko00000,ko02000	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FICKLOND_00056	2.94e-155	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
FICKLOND_00057	2.51e-191	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
FICKLOND_00058	3.05e-169	-	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
FICKLOND_00059	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
FICKLOND_00060	4.37e-124	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	adenylate kinase activity
FICKLOND_00061	8.78e-167	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
FICKLOND_00062	0.0	-	-	-	ET	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
FICKLOND_00064	2.9e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Semialdehyde dehydrogenase, NAD binding domain
FICKLOND_00065	3.21e-306	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FICKLOND_00066	1.44e-110	-	-	-	S	-	-	-	Putative zinc- or iron-chelating domain
FICKLOND_00067	7.7e-31	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
FICKLOND_00069	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	ATPases associated with a variety of cellular activities
FICKLOND_00070	4e-147	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
FICKLOND_00071	1.14e-126	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
FICKLOND_00072	7.06e-249	-	-	-	-	-	-	-	-
FICKLOND_00074	4.5e-176	-	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
FICKLOND_00075	3.65e-60	-	-	-	S	ko:K09131	-	ko00000	DUF167
FICKLOND_00076	1.72e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FICKLOND_00077	9.85e-262	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
FICKLOND_00078	4.47e-174	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
FICKLOND_00079	2.96e-242	-	3.1.3.18	-	F	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
FICKLOND_00080	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
FICKLOND_00081	2.91e-228	-	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
FICKLOND_00082	0.0	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Peptidase S24-like
FICKLOND_00083	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
FICKLOND_00084	6.29e-151	-	-	-	-	-	-	-	-
FICKLOND_00085	5.95e-167	pks6	-	-	Q	-	-	-	amino acid activation for nonribosomal peptide biosynthetic process
FICKLOND_00086	1.06e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF3485)
FICKLOND_00087	1.19e-229	-	-	-	C	-	-	-	Transmembrane exosortase (Exosortase_EpsH)
FICKLOND_00088	4.58e-220	prs	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FICKLOND_00089	5.05e-131	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FICKLOND_00091	1.48e-141	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
FICKLOND_00092	1.31e-147	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FICKLOND_00093	1.56e-60	-	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S6
FICKLOND_00094	2.97e-210	-	1.1.1.262	-	H	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal phosphate biosynthetic protein PdxA
FICKLOND_00097	3.37e-224	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
FICKLOND_00098	2.21e-254	-	2.7.1.11, 2.7.1.90	-	G	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Phosphofructokinase
FICKLOND_00099	2.58e-256	-	-	-	L	-	-	-	Membrane
FICKLOND_00100	6.18e-173	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	transporter
FICKLOND_00101	2.92e-233	-	-	-	CO	-	-	-	Protein of unknown function, DUF255
FICKLOND_00104	0.0	-	2.6.1.66	-	E	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
FICKLOND_00105	4.1e-193	-	-	-	S	-	-	-	Domain of unknown function (DUF1732)
FICKLOND_00106	4.39e-145	-	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
FICKLOND_00107	0.0	-	-	-	P	-	-	-	Citrate transporter
FICKLOND_00108	3.09e-208	-	-	-	J	ko:K01894	-	ko00000,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), catalytic domain
FICKLOND_00111	3.1e-217	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
FICKLOND_00112	5.46e-170	-	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
FICKLOND_00114	1.12e-217	-	-	-	-	-	-	-	-
FICKLOND_00115	3.17e-166	-	-	-	S	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
FICKLOND_00116	9.03e-173	-	-	-	T	-	-	-	Outer membrane lipoprotein-sorting protein
FICKLOND_00117	1.96e-226	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
FICKLOND_00118	0.0	secD	-	-	U	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FICKLOND_00120	1.62e-278	-	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
FICKLOND_00121	2.38e-258	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
FICKLOND_00122	2.95e-262	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FICKLOND_00123	4.19e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
FICKLOND_00124	1.54e-217	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Acyl transferase domain
FICKLOND_00126	1.63e-169	-	-	-	S	-	-	-	HAD-hyrolase-like
FICKLOND_00127	3.06e-286	-	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
FICKLOND_00128	1.21e-268	-	-	-	E	-	-	-	serine-type peptidase activity
FICKLOND_00129	3.2e-305	-	-	-	M	-	-	-	OmpA family
FICKLOND_00130	1.8e-215	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
FICKLOND_00131	0.0	-	-	-	M	-	-	-	Peptidase M60-like family
FICKLOND_00132	2.8e-295	-	-	-	EGP	-	-	-	Major facilitator Superfamily
FICKLOND_00133	0.0	-	-	-	KT	-	-	-	Sigma factor PP2C-like phosphatases
FICKLOND_00134	6.91e-165	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
FICKLOND_00135	3.33e-242	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
FICKLOND_00137	2.01e-157	-	-	-	NU	ko:K02457,ko:K08084	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	protein transport across the cell outer membrane
FICKLOND_00138	1.83e-188	-	-	-	-	-	-	-	-
FICKLOND_00139	5.15e-247	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
FICKLOND_00140	3.43e-183	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
FICKLOND_00141	4.06e-244	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
FICKLOND_00142	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
FICKLOND_00146	0.0	-	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
FICKLOND_00147	0.0	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FICKLOND_00148	9.26e-175	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
FICKLOND_00149	1.7e-154	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
FICKLOND_00150	2.54e-287	-	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FICKLOND_00151	1.29e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
FICKLOND_00153	0.0	-	-	-	T	-	-	-	pathogenesis
FICKLOND_00154	2.25e-91	-	-	-	O	-	-	-	response to oxidative stress
FICKLOND_00155	1.6e-293	-	2.3.1.31	-	E	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko01000	alpha/beta hydrolase fold
FICKLOND_00156	1.08e-63	-	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
FICKLOND_00157	0.0	-	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Glycosyltransferase family 9 (heptosyltransferase)
FICKLOND_00158	1.06e-188	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
FICKLOND_00159	0.0	-	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
FICKLOND_00160	1.15e-188	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
FICKLOND_00162	4.49e-187	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
FICKLOND_00163	0.0	-	-	-	EG	-	-	-	BNR repeat-like domain
FICKLOND_00164	0.0	legA	3.5.1.2	-	G	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	response to abiotic stimulus
FICKLOND_00165	1.32e-195	supH	-	-	Q	-	-	-	phosphatase activity
FICKLOND_00167	5.49e-85	nuoA	1.6.5.3	-	C	ko:K00330	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FICKLOND_00168	7.13e-276	-	-	-	G	-	-	-	Major Facilitator Superfamily
FICKLOND_00172	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
FICKLOND_00173	2.91e-38	-	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
FICKLOND_00174	5.25e-79	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FICKLOND_00180	1.79e-77	-	-	-	M	-	-	-	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FICKLOND_00181	6.05e-222	-	-	-	L	-	-	-	Transposase zinc-ribbon domain
FICKLOND_00182	0.0	-	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Peptidase family M50
FICKLOND_00185	0.0	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
FICKLOND_00186	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
FICKLOND_00187	3.07e-211	MA20_36650	-	-	EG	-	-	-	spore germination
FICKLOND_00188	3.57e-190	dpnC	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Dam-replacing family
FICKLOND_00189	0.0	-	-	-	S	-	-	-	Alpha-2-macroglobulin family
FICKLOND_00190	1.94e-289	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
FICKLOND_00192	2.89e-123	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
FICKLOND_00195	1.79e-213	-	-	-	-	-	-	-	-
FICKLOND_00196	3.97e-152	-	-	-	O	-	-	-	Glycoprotease family
FICKLOND_00197	4.28e-274	-	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
FICKLOND_00199	3.86e-112	-	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
FICKLOND_00200	4.12e-139	-	-	-	L	-	-	-	RNase_H superfamily
FICKLOND_00201	1.92e-102	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
FICKLOND_00202	4.3e-44	-	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	RNA polymerase activity
FICKLOND_00203	1.34e-135	-	5.4.99.20	-	J	ko:K06181	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
FICKLOND_00204	2.16e-188	-	-	-	-	-	-	-	-
FICKLOND_00205	1.3e-104	-	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	NDK
FICKLOND_00206	1.71e-201	-	-	-	S	-	-	-	Glycosyltransferase like family 2
FICKLOND_00207	4.12e-225	-	-	-	M	-	-	-	Glycosyl transferase family 2
FICKLOND_00209	7.26e-285	-	-	-	NU	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
FICKLOND_00210	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein E, N-terminal domain
FICKLOND_00211	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
FICKLOND_00212	4.22e-244	-	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FICKLOND_00213	2.83e-110	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
FICKLOND_00214	3.86e-281	-	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
FICKLOND_00215	0.0	murJ	-	-	S	ko:K03980	-	ko00000,ko01011,ko02000	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
FICKLOND_00216	1.21e-269	-	-	-	IM	-	-	-	Cytidylyltransferase-like
FICKLOND_00217	2.89e-156	-	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Iron/manganese superoxide dismutases, alpha-hairpin domain
FICKLOND_00218	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase-like 10
FICKLOND_00219	4.2e-171	-	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
FICKLOND_00220	1.39e-190	-	-	-	L	ko:K06864	-	ko00000	tRNA processing
FICKLOND_00221	3.77e-288	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FICKLOND_00222	1.07e-238	-	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Polyprenyl synthetase
FICKLOND_00223	0.0	-	-	-	E	ko:K03305	-	ko00000	POT family
FICKLOND_00224	0.0	-	5.2.1.8	-	O	ko:K03770	-	ko00000,ko01000,ko03110	PPIC-type PPIASE domain
FICKLOND_00225	2.39e-126	-	-	-	S	-	-	-	Pfam:DUF59
FICKLOND_00226	7.43e-107	-	-	-	-	-	-	-	-
FICKLOND_00228	8.93e-219	-	-	-	E	-	-	-	Domain of unknown function (DUF3472)
FICKLOND_00229	9.04e-317	nuoN	1.6.5.3	-	C	ko:K00343	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FICKLOND_00230	0.0	-	1.6.5.3	-	C	ko:K00342	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Proton-conducting membrane transporter
FICKLOND_00231	0.0	-	1.6.5.3	-	CP	ko:K00341	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
FICKLOND_00232	6.01e-61	nuoK	1.6.5.3	-	C	ko:K00340	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FICKLOND_00233	4.41e-156	-	1.6.5.3	-	C	ko:K00339	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone/plastoquinone oxidoreductase chain 6
FICKLOND_00234	1.8e-124	nuoI	1.6.5.3	-	C	ko:K00338	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FICKLOND_00235	1.04e-309	nuoH	1.6.5.3	-	C	ko:K00337	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FICKLOND_00236	0.0	-	1.6.5.3	-	C	ko:K00336	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
FICKLOND_00237	0.0	-	1.6.5.3	-	C	ko:K00335	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
FICKLOND_00238	2.88e-142	-	1.6.5.3	-	C	ko:K00334	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Thioredoxin-like [2Fe-2S] ferredoxin
FICKLOND_00239	4.39e-307	nuoD	1.6.5.3	-	C	ko:K00333	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FICKLOND_00241	0.0	-	-	-	G	-	-	-	Polysaccharide deacetylase
FICKLOND_00242	0.0	-	-	-	P	-	-	-	Putative Na+/H+ antiporter
FICKLOND_00243	1.07e-141	-	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Lumazine binding domain
FICKLOND_00244	7.24e-205	-	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
FICKLOND_00245	0.0	pmp21	-	-	T	-	-	-	pathogenesis
FICKLOND_00246	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
FICKLOND_00248	0.0	-	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Uncharacterized protein family UPF0004
FICKLOND_00249	0.0	-	-	-	-	ko:K07403	-	ko00000	-
FICKLOND_00250	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
FICKLOND_00251	0.0	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
FICKLOND_00252	3.72e-187	-	3.4.13.22	-	M	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-ala-D-ala dipeptidase
FICKLOND_00255	0.0	-	-	-	E	-	-	-	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FICKLOND_00256	0.0	-	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	tail specific protease
FICKLOND_00258	3.14e-213	-	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
FICKLOND_00259	0.0	-	3.6.4.13	-	L	ko:K03579	-	ko00000,ko01000	ATP-dependent helicase C-terminal
FICKLOND_00260	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
FICKLOND_00261	3.39e-311	-	-	-	O	-	-	-	peroxiredoxin activity
FICKLOND_00262	0.0	-	2.7.7.19	-	J	ko:K00970	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Poly A polymerase head domain
FICKLOND_00263	0.0	-	-	-	G	-	-	-	Alpha amylase, catalytic domain
FICKLOND_00264	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
FICKLOND_00265	0.0	-	-	-	-	-	-	-	-
FICKLOND_00266	7.21e-183	-	-	-	S	ko:K09778	-	ko00000	Domain of unknown function (DUF374)
FICKLOND_00267	7.21e-203	folD	1.5.1.5, 3.5.4.9	-	H	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FICKLOND_00268	2.91e-182	-	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
FICKLOND_00269	7.69e-138	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
FICKLOND_00270	4.88e-284	-	-	-	E	-	-	-	Transglutaminase-like superfamily
FICKLOND_00271	8.69e-261	-	-	-	J	ko:K05541	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FICKLOND_00272	1.31e-289	-	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	LytB protein
FICKLOND_00274	2.34e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S20
FICKLOND_00275	3.88e-140	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
FICKLOND_00276	0.0	-	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
FICKLOND_00277	1.27e-220	-	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Phosphatidylserine decarboxylase
FICKLOND_00278	1.1e-151	-	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3 epimerase family
FICKLOND_00279	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Leucyl-tRNA synthetase, Domain 2
FICKLOND_00280	0.0	-	-	-	P	-	-	-	Sulfatase
FICKLOND_00282	7.45e-301	-	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
FICKLOND_00283	0.0	-	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
FICKLOND_00284	3.33e-268	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
FICKLOND_00285	1.5e-161	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
FICKLOND_00286	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
FICKLOND_00287	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
FICKLOND_00288	0.0	rarA	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
FICKLOND_00289	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
FICKLOND_00291	3.87e-301	-	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
FICKLOND_00292	8.21e-215	-	-	-	M	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
FICKLOND_00293	3.61e-268	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
FICKLOND_00297	8.79e-263	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
FICKLOND_00298	0.0	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Type III restriction enzyme res subunit
FICKLOND_00299	0.0	-	-	-	L	-	-	-	Type III restriction enzyme res subunit
FICKLOND_00300	1.82e-126	cobU	2.7.1.156, 2.7.7.62, 6.3.5.10	-	H	ko:K02231,ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cobinamide kinase activity
FICKLOND_00301	6.74e-207	-	-	-	G	-	-	-	myo-inosose-2 dehydratase activity
FICKLOND_00302	6.59e-172	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FICKLOND_00303	4.02e-239	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FICKLOND_00304	9.28e-227	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FICKLOND_00305	0.0	cobQ	-	-	H	-	-	-	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
FICKLOND_00307	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
FICKLOND_00309	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
FICKLOND_00310	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
FICKLOND_00311	3.85e-159	-	-	-	M	ko:K16079	-	ko00000,ko02000	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FICKLOND_00312	1.9e-312	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
FICKLOND_00313	0.0	-	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
FICKLOND_00314	5.53e-96	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
FICKLOND_00315	8.04e-60	-	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	nucleotidyltransferase activity
FICKLOND_00316	1.47e-229	-	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
FICKLOND_00317	0.0	-	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoglutarate dehydrogenase C-terminal
FICKLOND_00318	1.48e-245	-	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit II
FICKLOND_00319	0.0	-	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
FICKLOND_00320	2.7e-113	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
FICKLOND_00321	2.34e-107	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
FICKLOND_00322	0.0	-	-	-	T	-	-	-	Chase2 domain
FICKLOND_00323	9.8e-232	-	2.7.1.221	-	S	ko:K07102	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Phosphotransferase enzyme family
FICKLOND_00324	1.25e-307	-	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FICKLOND_00325	4.98e-92	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
FICKLOND_00327	3.01e-113	-	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Ferritin-like domain
FICKLOND_00328	0.0	-	-	-	-	-	-	-	-
FICKLOND_00329	3.15e-103	-	-	-	J	-	-	-	YjgF/chorismate_mutase-like, putative endoribonuclease
FICKLOND_00331	7.16e-115	-	-	-	S	ko:K03748	-	ko00000	DUF218 domain
FICKLOND_00333	2.29e-229	-	-	-	S	-	-	-	mannose-ethanolamine phosphotransferase activity
FICKLOND_00337	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RQC
FICKLOND_00339	2.23e-176	-	-	-	-	-	-	-	-
FICKLOND_00340	3.89e-209	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FICKLOND_00341	2.18e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
FICKLOND_00342	6.3e-291	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FICKLOND_00343	2.23e-205	-	-	-	S	ko:K03453	-	ko00000	Bile acid
FICKLOND_00346	6.39e-71	-	-	-	-	-	-	-	-
FICKLOND_00347	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FICKLOND_00348	0.0	-	2.3.1.40, 6.2.1.20	-	IQ	ko:K05939	ko00071,ko00564,map00071,map00564	ko00000,ko00001,ko01000	AMP-binding enzyme
FICKLOND_00349	2.84e-41	-	-	-	T	-	-	-	pathogenesis
FICKLOND_00351	0.0	-	-	-	CO	-	-	-	Thioredoxin-like
FICKLOND_00356	3.35e-116	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FICKLOND_00357	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
FICKLOND_00358	1.22e-246	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
FICKLOND_00359	2.73e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
FICKLOND_00360	4.98e-117	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
FICKLOND_00361	1.16e-78	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
FICKLOND_00362	6.97e-241	-	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
FICKLOND_00363	1.55e-128	aroK	2.7.1.71	-	E	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FICKLOND_00364	9.56e-51	-	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S16
FICKLOND_00366	1.46e-07	-	-	-	E	-	-	-	LysE type translocator
FICKLOND_00367	1.31e-214	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
FICKLOND_00368	6.5e-186	-	-	-	DTZ	-	-	-	EF-hand, calcium binding motif
FICKLOND_00369	5.64e-66	-	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
FICKLOND_00370	1.39e-282	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
FICKLOND_00371	1.42e-149	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Putative methyltransferase
FICKLOND_00372	4.32e-174	-	-	-	F	-	-	-	NUDIX domain
FICKLOND_00373	5.96e-127	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
FICKLOND_00374	1.71e-207	-	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
FICKLOND_00375	1.9e-62	-	-	-	L	-	-	-	bacterial (prokaryotic) histone like domain
FICKLOND_00381	1.67e-141	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
FICKLOND_00382	3.02e-170	-	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FICKLOND_00383	3.33e-254	-	5.2.1.8	-	O	ko:K03771	-	ko00000,ko01000,ko03110	SurA N-terminal domain
FICKLOND_00384	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
FICKLOND_00385	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
FICKLOND_00386	6.2e-203	-	-	-	-	-	-	-	-
FICKLOND_00387	6.79e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FICKLOND_00388	2.19e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FICKLOND_00389	2.36e-34	-	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L29 protein
FICKLOND_00390	3.42e-97	-	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FICKLOND_00391	5.2e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FICKLOND_00392	4.97e-70	-	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
FICKLOND_00393	4.05e-152	-	-	-	-	-	-	-	-
FICKLOND_00394	1.05e-58	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FICKLOND_00395	1.85e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FICKLOND_00396	8.72e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
FICKLOND_00397	1.9e-131	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L4/L1 family
FICKLOND_00398	3.86e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FICKLOND_00399	3.67e-65	-	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S10p/S20e
FICKLOND_00400	0.0	-	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FICKLOND_00401	2.91e-104	-	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S7p/S5e
FICKLOND_00402	4.16e-85	-	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S12/S23
FICKLOND_00403	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	BPG-independent PGAM N-terminus (iPGM_N)
FICKLOND_00404	3.37e-97	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase superfamily
FICKLOND_00405	1.82e-274	-	-	-	T	-	-	-	PAS domain
FICKLOND_00406	0.0	-	-	-	T	-	-	-	Bacterial regulatory protein, Fis family
FICKLOND_00407	0.0	-	-	-	O	-	-	-	C-terminal four TMM region of protein-O-mannosyltransferase
FICKLOND_00408	3.08e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
FICKLOND_00409	0.0	dxs	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FICKLOND_00410	3.99e-183	-	-	-	S	-	-	-	Tetratricopeptide repeat
FICKLOND_00411	2.31e-127	-	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Recombination protein O N terminal
FICKLOND_00412	9.67e-251	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
FICKLOND_00413	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
FICKLOND_00414	2.05e-229	-	-	-	EP	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
FICKLOND_00415	3.07e-155	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
FICKLOND_00417	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
FICKLOND_00418	4.97e-168	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
FICKLOND_00419	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
FICKLOND_00420	2.52e-205	-	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
FICKLOND_00422	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
FICKLOND_00423	3.42e-111	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
FICKLOND_00425	1.86e-94	-	-	-	O	-	-	-	OsmC-like protein
FICKLOND_00426	0.0	-	-	-	CO	-	-	-	Disulphide bond corrector protein DsbC
FICKLOND_00427	1.14e-175	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
FICKLOND_00428	7.58e-140	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease
FICKLOND_00429	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FICKLOND_00430	4.69e-79	rsfS	-	-	S	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
FICKLOND_00431	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FICKLOND_00433	6.38e-258	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
FICKLOND_00434	4.36e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Enoyl-CoA hydratase/isomerase
FICKLOND_00437	1.85e-302	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	efflux transmembrane transporter activity
FICKLOND_00441	9.85e-147	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
FICKLOND_00444	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
FICKLOND_00445	8.38e-98	-	-	-	-	-	-	-	-
FICKLOND_00446	3.14e-192	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
FICKLOND_00447	0.0	-	-	-	S	-	-	-	Fungal chitosanase of glycosyl hydrolase group 75
FICKLOND_00448	9.68e-221	-	2.5.1.21	-	I	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01006	Squalene/phytoene synthase
FICKLOND_00449	0.0	-	-	-	KT	ko:K02584	ko02020,map02020	ko00000,ko00001,ko03000	Bacterial regulatory protein, Fis family
FICKLOND_00450	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
FICKLOND_00452	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
FICKLOND_00454	0.0	-	-	-	-	-	-	-	-
FICKLOND_00455	0.0	-	4.1.1.15	-	E	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase conserved domain
FICKLOND_00456	5.21e-142	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
FICKLOND_00457	0.0	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase alpha chain like domain
FICKLOND_00458	4.25e-238	pyrD	1.3.5.2	-	F	ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
FICKLOND_00459	4.7e-156	-	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase
FICKLOND_00460	1.1e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
FICKLOND_00461	1.63e-164	-	-	-	CO	-	-	-	Thioredoxin-like
FICKLOND_00462	0.0	-	-	-	C	-	-	-	Cytochrome c554 and c-prime
FICKLOND_00463	3.4e-311	-	-	-	S	-	-	-	PFAM CBS domain containing protein
FICKLOND_00464	9.05e-313	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	PFAM CBS domain containing protein
FICKLOND_00465	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
FICKLOND_00466	3.01e-49	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal_S15
FICKLOND_00467	2.32e-151	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
FICKLOND_00468	2.46e-215	-	-	-	D	ko:K19234,ko:K19236	ko01503,map01503	ko00000,ko00001,ko01002,ko01011	ErfK ybiS ycfS ynhG family protein
FICKLOND_00469	0.0	-	-	-	S	-	-	-	Terminase
FICKLOND_00472	7.54e-201	-	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
FICKLOND_00473	1.04e-144	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FICKLOND_00474	9.86e-168	-	-	-	M	-	-	-	Peptidase family M23
FICKLOND_00475	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	PFAM coagulation factor 5 8 type domain protein
FICKLOND_00477	1.33e-174	-	-	-	NU	-	-	-	Prepilin-type N-terminal cleavage methylation domain
FICKLOND_00478	1.16e-178	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FICKLOND_00479	0.0	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
FICKLOND_00480	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
FICKLOND_00481	6.94e-153	-	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	AAA domain
FICKLOND_00483	4.86e-201	-	-	-	S	-	-	-	DisA bacterial checkpoint controller nucleotide-binding
FICKLOND_00484	6.25e-144	-	-	-	-	-	-	-	-
FICKLOND_00485	6.38e-151	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
FICKLOND_00486	3.42e-196	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FICKLOND_00487	1.48e-120	-	-	-	M	ko:K06142	-	ko00000	Outer membrane protein (OmpH-like)
FICKLOND_00488	5.68e-188	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FICKLOND_00489	1.2e-196	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
FICKLOND_00490	5.69e-190	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
FICKLOND_00491	6.06e-251	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
FICKLOND_00493	4.48e-223	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
FICKLOND_00494	6.23e-118	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Polynucleotide kinase 3 phosphatase
FICKLOND_00495	8.25e-131	-	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
FICKLOND_00496	0.0	-	2.7.1.167, 2.7.7.70	-	M	ko:K03272	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	pfkB family carbohydrate kinase
FICKLOND_00497	1.06e-44	-	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S21
FICKLOND_00498	1.05e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
FICKLOND_00499	5.67e-258	-	-	-	S	-	-	-	ankyrin repeats
FICKLOND_00500	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
FICKLOND_00501	0.0	-	-	-	-	-	-	-	-
FICKLOND_00502	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), anti-codon binding domain
FICKLOND_00503	9.59e-288	-	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase II
FICKLOND_00504	8.55e-104	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
FICKLOND_00505	8.13e-206	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FICKLOND_00506	1.1e-197	-	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SRP54-type protein, GTPase domain
FICKLOND_00507	6.16e-261	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Elongator protein 3, MiaB family, Radical SAM
FICKLOND_00508	0.0	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
FICKLOND_00509	1.6e-182	-	-	-	U	ko:K20276	ko02024,map02024	ko00000,ko00001	domain, Protein
FICKLOND_00510	5.7e-153	-	-	-	O	-	-	-	methyltransferase activity
FICKLOND_00511	7.21e-290	-	3.5.1.42	-	S	ko:K03742	ko00760,map00760	ko00000,ko00001,ko01000	Competence-damaged protein
FICKLOND_00512	0.0	-	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
FICKLOND_00513	4.37e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
FICKLOND_00517	4.02e-191	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
FICKLOND_00518	4.36e-142	-	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S4/S9 N-terminal domain
FICKLOND_00519	2.11e-121	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FICKLOND_00520	1.11e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FICKLOND_00521	1.59e-269	-	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
FICKLOND_00522	1.18e-224	-	-	-	M	ko:K07276	-	ko00000	Mitochondrial fission ELM1
FICKLOND_00523	1.21e-268	-	-	-	M	-	-	-	Glycosyl transferase 4-like
FICKLOND_00524	6.26e-269	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
FICKLOND_00525	9.59e-216	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
FICKLOND_00526	1.11e-261	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
FICKLOND_00527	2.85e-267	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Aminomethyltransferase folate-binding domain
FICKLOND_00528	6.67e-86	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
FICKLOND_00529	0.0	gcvP	1.4.4.2	-	E	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FICKLOND_00531	6.18e-150	-	-	-	L	-	-	-	Membrane
FICKLOND_00532	0.0	-	-	-	P	ko:K01138	-	ko00000,ko01000	PA14 domain
FICKLOND_00533	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DbpA RNA binding domain
FICKLOND_00534	1.02e-174	-	-	-	-	-	-	-	-
FICKLOND_00535	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
FICKLOND_00536	9.94e-243	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
FICKLOND_00537	1.84e-105	-	-	-	S	ko:K15977	-	ko00000	DoxX
FICKLOND_00538	4.75e-245	-	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR synthase related protein, N-terminal domain
FICKLOND_00539	0.0	-	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FICKLOND_00540	1.26e-139	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
FICKLOND_00542	2.34e-208	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
FICKLOND_00543	1.31e-81	-	-	-	DJ	-	-	-	Addiction module toxin, RelE StbE family
FICKLOND_00544	8.37e-126	-	4.1.1.36	-	H	ko:K01598	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Flavoprotein
FICKLOND_00546	2.31e-259	-	-	-	M	-	-	-	Peptidase family M23
FICKLOND_00547	0.0	-	-	-	S	-	-	-	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FICKLOND_00548	0.0	-	-	-	L	-	-	-	Polyphosphate kinase 2 (PPK2)
FICKLOND_00549	2.48e-173	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
FICKLOND_00550	1.94e-104	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
FICKLOND_00551	9.7e-279	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
FICKLOND_00552	2.4e-160	-	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	DNA / pantothenate metabolism flavoprotein
FICKLOND_00553	1.67e-272	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
FICKLOND_00554	9.68e-226	-	-	-	S	-	-	-	Aspartyl protease
FICKLOND_00555	1.18e-309	-	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
FICKLOND_00556	3.35e-131	-	-	-	L	-	-	-	Conserved hypothetical protein 95
FICKLOND_00557	1.36e-175	-	-	-	-	-	-	-	-
FICKLOND_00559	2.58e-225	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
FICKLOND_00560	0.0	-	-	-	-	-	-	-	-
FICKLOND_00561	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
FICKLOND_00563	1.07e-199	-	-	-	S	ko:K06889	-	ko00000	alpha beta
FICKLOND_00564	1.65e-106	-	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
FICKLOND_00565	1.93e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal prokaryotic L21 protein
FICKLOND_00566	2.14e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
FICKLOND_00567	6.78e-100	-	-	-	P	ko:K09825	-	ko00000,ko03000	Ferric uptake regulator family
FICKLOND_00568	8.34e-178	-	-	-	O	ko:K09013	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
FICKLOND_00569	0.0	-	-	-	O	ko:K09014	-	ko00000	Uncharacterized protein family (UPF0051)
FICKLOND_00570	2.6e-296	-	-	-	O	ko:K09015	-	ko00000	Uncharacterized protein family (UPF0051)
FICKLOND_00571	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
FICKLOND_00572	0.0	-	-	-	P	-	-	-	Sulfatase
FICKLOND_00573	2.93e-233	-	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Biotin and Thiamin Synthesis associated domain
FICKLOND_00574	0.0	-	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
FICKLOND_00577	1.85e-75	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
FICKLOND_00578	1.08e-73	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
FICKLOND_00579	7.63e-220	-	-	-	M	-	-	-	Glycosyl transferase family 2
FICKLOND_00580	4.94e-114	flmH	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FICKLOND_00581	7.67e-285	-	2.6.1.59	-	M	ko:K02805	-	ko00000,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
FICKLOND_00582	4.27e-275	-	-	-	S	-	-	-	COGs COG4299 conserved
FICKLOND_00583	8.17e-124	sprT	-	-	K	-	-	-	SprT-like family
FICKLOND_00584	1.38e-139	-	-	-	-	-	-	-	-
FICKLOND_00585	1.24e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
FICKLOND_00586	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FICKLOND_00587	4.5e-201	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FICKLOND_00588	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FICKLOND_00589	6.46e-86	-	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase delta (OSCP) subunit
FICKLOND_00590	4.38e-78	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase B/B' CF(0)
FICKLOND_00591	1.65e-11	-	-	-	S	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	PFAM H transporting two-sector ATPase C subunit
FICKLOND_00592	6.27e-219	-	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	ATP synthase A chain
FICKLOND_00593	0.0	-	-	-	-	-	-	-	-
FICKLOND_00594	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein dimerisation domain
FICKLOND_00595	5.1e-153	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
FICKLOND_00596	3.11e-271	-	-	-	S	-	-	-	COGs COG4299 conserved
FICKLOND_00597	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
FICKLOND_00599	4.09e-218	-	-	-	I	-	-	-	alpha/beta hydrolase fold
FICKLOND_00600	2.89e-223	-	-	-	-	-	-	-	-
FICKLOND_00601	3.67e-126	-	-	-	U	-	-	-	response to pH
FICKLOND_00602	9.39e-183	-	-	-	H	-	-	-	ThiF family
FICKLOND_00603	1.18e-224	-	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
FICKLOND_00604	4.7e-193	-	-	-	-	-	-	-	-
FICKLOND_00605	2.76e-292	-	4.2.1.129, 5.4.99.17	-	I	ko:K06045	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
FICKLOND_00606	1.06e-109	-	-	-	S	ko:K15977	-	ko00000	DoxX
FICKLOND_00607	1.34e-201	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase, N-terminal
FICKLOND_00608	6.75e-305	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FICKLOND_00609	1.05e-180	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FICKLOND_00610	0.0	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FICKLOND_00611	0.0	-	-	-	K	-	-	-	Transcription elongation factor, N-terminal
FICKLOND_00612	1.89e-166	-	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	SAICAR synthetase
FICKLOND_00613	2.26e-115	-	-	-	-	-	-	-	-
FICKLOND_00614	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
FICKLOND_00615	7.5e-177	-	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
FICKLOND_00617	2.24e-263	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
FICKLOND_00619	0.0	lacZ_17	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
FICKLOND_00620	5.06e-236	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Actin
FICKLOND_00621	0.0	-	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	Ribonuclease E/G family
FICKLOND_00622	8.99e-277	-	-	-	K	-	-	-	sequence-specific DNA binding
FICKLOND_00623	5.47e-195	-	-	-	-	-	-	-	-
FICKLOND_00624	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
FICKLOND_00626	4.52e-101	exbD2	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
FICKLOND_00627	1.65e-113	aglS	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
FICKLOND_00628	9.91e-171	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
FICKLOND_00629	2.15e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FICKLOND_00630	1.39e-157	-	-	-	S	-	-	-	3D domain
FICKLOND_00631	3.4e-229	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
FICKLOND_00632	1.67e-177	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
FICKLOND_00634	4.83e-82	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
FICKLOND_00635	2.51e-151	-	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
FICKLOND_00636	4.77e-310	-	-	-	S	-	-	-	PFAM CBS domain containing protein
FICKLOND_00637	8.43e-59	-	-	-	S	-	-	-	Zinc ribbon domain
FICKLOND_00638	2.79e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FICKLOND_00640	2.9e-316	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Arginosuccinate synthase
FICKLOND_00641	9.36e-114	-	3.1.6.8	-	P	ko:K01134	ko00600,ko04142,map00600,map04142	ko00000,ko00001,ko01000	COG3119 Arylsulfatase A
FICKLOND_00642	2.6e-298	-	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	16S rRNA methyltransferase RsmB/F
FICKLOND_00643	4.82e-178	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
FICKLOND_00644	1.06e-163	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
FICKLOND_00645	2.63e-143	-	-	-	-	-	-	-	-
FICKLOND_00646	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Sulfatase
FICKLOND_00650	6.79e-100	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
FICKLOND_00651	2.51e-182	-	-	-	S	-	-	-	competence protein
FICKLOND_00652	2.92e-70	-	-	-	-	-	-	-	-
FICKLOND_00653	1.97e-189	-	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	MazG nucleotide pyrophosphohydrolase domain
FICKLOND_00654	3.03e-74	-	-	-	-	-	-	-	-
FICKLOND_00655	2.24e-264	-	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
FICKLOND_00656	1.94e-140	-	-	-	S	ko:K07164	-	ko00000	C4-type zinc ribbon domain
FICKLOND_00657	2.22e-298	lpxK	2.7.1.130	-	M	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
FICKLOND_00658	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
FICKLOND_00659	2.13e-118	-	-	-	-	-	-	-	-
FICKLOND_00660	1.99e-233	-	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	prohibitin homologues
FICKLOND_00661	0.000103	-	-	-	S	-	-	-	Entericidin EcnA/B family
FICKLOND_00663	6.18e-205	-	1.4.1.16	-	S	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
FICKLOND_00664	8.36e-174	-	-	-	S	-	-	-	peptidoglycan biosynthetic process
FICKLOND_00665	5.39e-136	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
FICKLOND_00666	2.05e-173	-	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	FtsJ-like methyltransferase
FICKLOND_00668	1.84e-171	-	-	-	S	ko:K06911	-	ko00000	Pirin
FICKLOND_00669	0.0	-	-	-	M	-	-	-	AsmA-like C-terminal region
FICKLOND_00671	1.03e-201	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
FICKLOND_00672	0.0	-	2.7.1.51	-	G	ko:K00879	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
FICKLOND_00674	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
FICKLOND_00675	8.76e-34	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
FICKLOND_00676	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
FICKLOND_00677	1.12e-121	-	-	-	-	-	-	-	-
FICKLOND_00678	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	N-terminal domain of BNR-repeat neuraminidase
FICKLOND_00679	2.06e-133	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
FICKLOND_00680	7.29e-60	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
FICKLOND_00681	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
FICKLOND_00682	0.0	-	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	ThiC-associated domain
FICKLOND_00683	2.19e-220	ytpP	2.7.1.180, 5.3.4.1	-	CO	ko:K01829,ko:K03671,ko:K03734,ko:K06196	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko02000,ko03110	cell redox homeostasis
FICKLOND_00684	1.3e-139	-	-	-	K	-	-	-	ECF sigma factor
FICKLOND_00686	4.78e-222	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
FICKLOND_00687	3.06e-232	-	-	-	O	-	-	-	Parallel beta-helix repeats
FICKLOND_00688	0.0	-	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
FICKLOND_00689	1.95e-284	-	-	-	Q	-	-	-	Multicopper oxidase
FICKLOND_00690	1.16e-209	-	-	-	EG	-	-	-	EamA-like transporter family
FICKLOND_00692	2.2e-274	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FICKLOND_00693	6.48e-244	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
FICKLOND_00694	9.42e-232	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
FICKLOND_00695	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
FICKLOND_00696	0.0	-	-	-	P	ko:K13895	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
FICKLOND_00697	0.0	-	-	-	EP	ko:K13894	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
FICKLOND_00698	1.4e-185	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
FICKLOND_00699	1.35e-207	-	-	-	S	-	-	-	Tetratricopeptide repeat
FICKLOND_00700	9.98e-223	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase PanE/ApbA C terminal
FICKLOND_00701	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate--tetrahydrofolate ligase
FICKLOND_00702	5.77e-145	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
FICKLOND_00703	8.95e-316	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
FICKLOND_00704	3.77e-118	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
FICKLOND_00705	2.52e-281	-	5.4.99.22	-	M	ko:K06178	-	ko00000,ko01000,ko03009	translation initiation factor activity
FICKLOND_00706	1.27e-133	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
FICKLOND_00707	7.4e-93	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
FICKLOND_00708	8.02e-130	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
FICKLOND_00709	8.59e-293	-	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 57
FICKLOND_00710	1.25e-315	-	-	-	G	-	-	-	Glycosyl transferase 4-like domain
FICKLOND_00711	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 31
FICKLOND_00712	6.05e-250	-	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	chorismate binding enzyme
FICKLOND_00713	3.89e-313	-	-	-	C	ko:K00185	-	ko00000	Polysulphide reductase, NrfD
FICKLOND_00715	7.47e-156	-	-	-	C	-	-	-	Cytochrome c
FICKLOND_00716	4.3e-296	-	-	-	P	-	-	-	ABC-type Zn2 transport system, periplasmic component surface adhesin
FICKLOND_00717	5.03e-313	-	-	-	C	-	-	-	Cytochrome c
FICKLOND_00718	3.37e-154	-	-	-	C	-	-	-	Cytochrome c
FICKLOND_00720	1.38e-60	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FICKLOND_00721	1.13e-270	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
FICKLOND_00722	6.74e-307	-	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
FICKLOND_00723	1.05e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
FICKLOND_00724	2.48e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
FICKLOND_00725	0.0	-	-	-	J	-	-	-	Beta-Casp domain
FICKLOND_00726	4.02e-144	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FICKLOND_00727	1.02e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Queuosine biosynthesis protein QueC
FICKLOND_00728	1.78e-97	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	QueF-like protein
FICKLOND_00729	0.0	kefA	-	-	M	ko:K05802,ko:K22051	-	ko00000,ko02000	cellular water homeostasis
FICKLOND_00730	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FICKLOND_00731	7.46e-238	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FICKLOND_00732	1.44e-191	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin resistance protein BacA
FICKLOND_00735	1.05e-84	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
FICKLOND_00736	4.68e-315	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
FICKLOND_00738	1.65e-303	-	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
FICKLOND_00739	1.33e-52	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
FICKLOND_00740	4.17e-260	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FICKLOND_00742	8.29e-100	cysJ	1.8.1.2	-	C	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	hydroxylamine reductase activity
FICKLOND_00744	5.74e-200	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
FICKLOND_00745	1.06e-169	BT0174	-	-	C	ko:K04488	-	ko00000	iron-sulfur transferase activity
FICKLOND_00746	2.08e-240	BT0173	-	-	S	-	-	-	Psort location Cytoplasmic, score
FICKLOND_00748	7.78e-269	-	2.1.1.72	-	H	ko:K07318	-	ko00000,ko01000,ko02048	PFAM D12 class N6 adenine-specific DNA methyltransferase
FICKLOND_00749	6.72e-210	-	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
FICKLOND_00754	3.48e-274	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
FICKLOND_00755	6.02e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FICKLOND_00756	2.49e-229	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
FICKLOND_00757	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
FICKLOND_00758	4.66e-230	-	2.7.7.13	-	JM	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
FICKLOND_00759	4.47e-176	-	-	-	S	-	-	-	Phosphodiester glycosidase
FICKLOND_00760	0.0	-	-	GT2	M	ko:K03820	-	ko00000,ko01000	Carbon-nitrogen hydrolase
FICKLOND_00761	1.33e-51	-	-	-	C	-	-	-	4Fe-4S single cluster domain of Ferredoxin I
FICKLOND_00762	1.12e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
FICKLOND_00763	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
FICKLOND_00764	2.52e-237	-	-	-	S	-	-	-	Acyltransferase family
FICKLOND_00765	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
FICKLOND_00766	2.69e-185	ccs1	-	-	O	ko:K07399	-	ko00000	cytochrome c biogenesis protein
FICKLOND_00767	2.42e-209	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion transport
FICKLOND_00768	1.06e-180	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
FICKLOND_00769	1.23e-228	fatC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
FICKLOND_00770	4.39e-219	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
FICKLOND_00771	2.43e-264	-	-	-	J	-	-	-	Endoribonuclease L-PSP
FICKLOND_00772	0.0	-	-	-	C	-	-	-	Di-haem oxidoreductase, putative peroxidase
FICKLOND_00773	7.56e-246	-	-	-	S	-	-	-	Imelysin
FICKLOND_00774	6.48e-142	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
FICKLOND_00776	1.82e-125	-	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Phosphoribosyl transferase domain
FICKLOND_00777	0.0	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	Helix-hairpin-helix class 2 (Pol1 family) motifs
FICKLOND_00778	1.37e-249	-	-	-	M	-	-	-	HlyD family secretion protein
FICKLOND_00779	1.78e-102	MA20_05485	-	-	S	-	-	-	Putative bacterial sensory transduction regulator
FICKLOND_00780	0.0	-	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
FICKLOND_00781	1.46e-302	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
FICKLOND_00782	0.0	-	-	-	D	-	-	-	Tetratricopeptide repeat
FICKLOND_00783	1.47e-193	-	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
FICKLOND_00784	0.0	-	-	-	-	-	-	-	-
FICKLOND_00785	6.55e-222	-	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
FICKLOND_00786	6.68e-314	-	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
FICKLOND_00787	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
FICKLOND_00788	5.32e-148	-	4.1.3.38	-	E	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	branched-chain-amino-acid transaminase activity
FICKLOND_00789	1.04e-246	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FICKLOND_00790	2.09e-150	-	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
FICKLOND_00791	4.49e-269	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
FICKLOND_00792	2.5e-170	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
FICKLOND_00793	2.11e-118	-	-	-	T	ko:K07005	-	ko00000	pyridoxamine 5'-phosphate
FICKLOND_00794	7.17e-172	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Glutamine amidotransferase class-I
FICKLOND_00796	2.87e-112	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Cys-tRNA(Pro) hydrolase activity
FICKLOND_00797	0.0	mmyX	5.3.1.12	-	F	ko:K01812,ko:K07149,ko:K16139	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score
FICKLOND_00798	6.74e-106	-	-	-	-	-	-	-	-
FICKLOND_00800	4.37e-147	-	-	-	Q	-	-	-	PA14
FICKLOND_00802	0.0	-	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	B12 binding domain
FICKLOND_00803	1.66e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
FICKLOND_00804	1.45e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
FICKLOND_00805	2.37e-312	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
FICKLOND_00806	1.3e-06	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain protein
FICKLOND_00807	6.62e-57	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	DNA specificity domain
FICKLOND_00808	6.93e-141	-	-	-	K	-	-	-	Fic/DOC family
FICKLOND_00809	1.36e-168	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
FICKLOND_00810	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
FICKLOND_00812	0.0	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
FICKLOND_00813	2.52e-281	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
FICKLOND_00814	1.12e-116	agmK	1.8.1.8	-	O	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	belongs to the thioredoxin family
FICKLOND_00815	2.72e-181	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
FICKLOND_00817	0.0	-	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
FICKLOND_00818	2.18e-218	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FICKLOND_00819	5.88e-259	-	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	endonuclease III
FICKLOND_00820	4.25e-144	aat	2.3.2.6	-	O	ko:K00684	-	ko00000,ko01000	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FICKLOND_00821	0.0	-	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Pyruvate phosphate dikinase, PEP/pyruvate binding domain
FICKLOND_00822	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglucose isomerase
FICKLOND_00823	3.86e-261	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
FICKLOND_00824	4.45e-225	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
FICKLOND_00826	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
FICKLOND_00827	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
FICKLOND_00828	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
FICKLOND_00829	2.94e-131	-	-	-	-	-	-	-	-
FICKLOND_00830	2.75e-244	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
FICKLOND_00833	8.93e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyrroline-5-carboxylate reductase dimerisation
FICKLOND_00834	4.69e-159	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
FICKLOND_00835	5.51e-211	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
FICKLOND_00836	6.59e-227	-	-	-	S	-	-	-	Protein conserved in bacteria
FICKLOND_00837	2.01e-34	-	-	-	KLT	-	-	-	Tyrosine-protein kinase, subgroup, catalytic domain
FICKLOND_00838	0.0	-	4.1.99.1	-	E	ko:K01667	ko00380,map00380	ko00000,ko00001,ko01000	Beta-eliminating lyase
FICKLOND_00839	6.76e-143	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
FICKLOND_00840	1.75e-255	-	-	-	S	-	-	-	Domain of unknown function (DUF4105)
FICKLOND_00841	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	B3/4 domain
FICKLOND_00842	6.99e-242	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Aminoacyl tRNA synthetase class II, N-terminal domain
FICKLOND_00843	1.11e-283	-	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
FICKLOND_00844	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
FICKLOND_00845	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Hsp90 protein
FICKLOND_00846	6.67e-172	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
FICKLOND_00847	1.95e-273	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FICKLOND_00848	9.25e-103	-	-	-	K	-	-	-	Transcriptional regulator
FICKLOND_00849	8.64e-312	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
FICKLOND_00850	9.2e-215	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
FICKLOND_00851	8.4e-136	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K00788,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
FICKLOND_00852	1.15e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FICKLOND_00853	4.27e-117	gepA	-	-	K	-	-	-	Phage-associated protein
FICKLOND_00859	0.0	-	-	-	M	-	-	-	pathogenesis
FICKLOND_00861	1.3e-265	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
FICKLOND_00867	4.6e-149	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
FICKLOND_00870	2.94e-31	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
FICKLOND_00871	3.45e-31	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
FICKLOND_00872	4.74e-07	-	-	-	KLT	-	-	-	Lanthionine synthetase C-like protein
FICKLOND_00873	8.51e-46	-	-	-	S	-	-	-	von Willebrand factor type A domain
FICKLOND_00874	1.63e-121	-	-	-	S	-	-	-	Virulence protein RhuM family
FICKLOND_00875	5.3e-07	RIPK1	2.7.11.1	-	T	ko:K02861	ko04064,ko04210,ko04217,ko04620,ko04621,ko04622,ko04623,ko04668,ko05160,ko05169,map04064,map04210,map04217,map04620,map04621,map04622,map04623,map04668,map05160,map05169	ko00000,ko00001,ko01000,ko01001	Receptor (TNFRSF)-interacting serine-threonine kinase 1
FICKLOND_00879	9.42e-07	-	-	-	S	-	-	-	TM2 domain
FICKLOND_00883	4.43e-39	-	-	-	-	-	-	-	-
FICKLOND_00884	5.53e-96	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
FICKLOND_00885	3.15e-200	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
FICKLOND_00886	2.43e-101	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
FICKLOND_00887	9.77e-293	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
FICKLOND_00888	3.62e-108	-	-	-	S	-	-	-	Meiotically up-regulated gene 113
FICKLOND_00889	1.19e-47	-	-	-	S	-	-	-	Domain of unknown function (DUF932)
FICKLOND_00896	0.0	-	-	-	P	-	-	-	Cation transport protein
FICKLOND_00897	2.48e-300	-	-	-	V	ko:K03327	-	ko00000,ko02000	drug transmembrane transporter activity
FICKLOND_00898	1.83e-120	-	-	-	-	-	-	-	-
FICKLOND_00899	9.86e-54	-	-	-	-	-	-	-	-
FICKLOND_00900	7.2e-103	-	-	-	-	-	-	-	-
FICKLOND_00901	0.0	-	2.1.1.182	-	IJ	ko:K02528	-	ko00000,ko01000,ko03009	Ribosomal RNA adenine dimethylases
FICKLOND_00902	1.26e-247	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
FICKLOND_00903	5.41e-278	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
FICKLOND_00904	3.1e-270	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
FICKLOND_00905	6.39e-119	-	-	-	T	-	-	-	STAS domain
FICKLOND_00906	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2851)
FICKLOND_00907	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
FICKLOND_00908	3.09e-290	-	-	-	-	-	-	-	-
FICKLOND_00909	0.0	-	-	-	M	-	-	-	Sulfatase
FICKLOND_00910	6.68e-286	-	4.1.99.19	-	H	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Biotin and Thiamin Synthesis associated domain
FICKLOND_00911	6.59e-205	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
FICKLOND_00912	4.71e-267	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
FICKLOND_00913	0.0	-	-	-	T	-	-	-	pathogenesis
FICKLOND_00914	0.0	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Dehydratase family
FICKLOND_00915	6.89e-168	-	-	-	T	ko:K07657	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
FICKLOND_00916	5.8e-289	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
FICKLOND_00917	2.09e-10	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
FICKLOND_00918	1.11e-206	hisG	2.4.2.17	-	E	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
FICKLOND_00919	2.04e-314	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
FICKLOND_00920	5.68e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF3313)
FICKLOND_00921	2.93e-260	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FICKLOND_00922	9.39e-256	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
FICKLOND_00923	2.8e-169	-	-	-	-	-	-	-	-
FICKLOND_00924	0.0	-	-	-	NU	-	-	-	Type IV pilus assembly protein PilM;
FICKLOND_00925	6.11e-208	-	-	-	-	-	-	-	-
FICKLOND_00926	2.27e-245	-	-	-	-	-	-	-	-
FICKLOND_00927	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
FICKLOND_00928	1.85e-142	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FICKLOND_00929	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FICKLOND_00930	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
FICKLOND_00931	1.65e-240	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
FICKLOND_00932	1.1e-131	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
FICKLOND_00933	5.44e-229	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FICKLOND_00934	0.0	-	1.11.1.5	-	P	ko:K00428	-	ko00000,ko01000	Di-haem cytochrome c peroxidase
FICKLOND_00935	2.48e-40	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
FICKLOND_00936	4.02e-48	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
FICKLOND_00937	0.0	-	-	-	P	ko:K04759	-	ko00000,ko02000	Ferrous iron transport protein B C terminus
FICKLOND_00940	2.83e-303	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
FICKLOND_00942	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
FICKLOND_00943	4.92e-90	-	-	-	K	-	-	-	Helix-turn-helix diphteria tox regulatory element
FICKLOND_00944	4.56e-206	-	3.1.1.53	-	L	ko:K03547,ko:K05970	-	ko00000,ko01000,ko03400	3'-5' exonuclease activity
FICKLOND_00945	2.86e-133	-	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	SpoU rRNA Methylase family
FICKLOND_00946	0.0	-	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
FICKLOND_00947	9.76e-258	-	-	-	S	-	-	-	Glycoside-hydrolase family GH114
FICKLOND_00948	8.72e-301	-	-	-	M	-	-	-	Glycosyl transferases group 1
FICKLOND_00950	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RecQ zinc-binding
FICKLOND_00951	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
FICKLOND_00952	8.66e-227	-	-	-	-	-	-	-	-
FICKLOND_00953	1.97e-316	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
FICKLOND_00954	8.88e-247	-	-	-	-	-	-	-	-
FICKLOND_00955	3.5e-249	rgpB	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
FICKLOND_00956	0.0	ahcY	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FICKLOND_00957	3.77e-291	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FICKLOND_00958	3.9e-214	-	-	-	KQ	-	-	-	Hypothetical methyltransferase
FICKLOND_00961	0.0	-	-	-	E	-	-	-	PFAM major facilitator superfamily MFS_1
FICKLOND_00962	3.17e-206	-	-	-	G	ko:K06867,ko:K07001	-	ko00000	response to abiotic stimulus
FICKLOND_00964	1.01e-293	-	-	-	MU	ko:K15725	-	ko00000,ko02000	efflux transmembrane transporter activity
FICKLOND_00965	1.96e-297	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FICKLOND_00966	0.0	-	-	-	P	ko:K07239	-	ko00000	AcrB/AcrD/AcrF family
FICKLOND_00967	3.44e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
FICKLOND_00969	2.38e-169	-	-	-	CO	-	-	-	Protein conserved in bacteria
FICKLOND_00970	2.6e-231	-	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
FICKLOND_00971	4.84e-155	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
FICKLOND_00972	0.0	-	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Surface antigen
FICKLOND_00973	8.38e-282	tig	-	-	O	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
FICKLOND_00974	2.5e-153	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
FICKLOND_00975	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FICKLOND_00976	3.39e-254	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FICKLOND_00978	9.94e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FICKLOND_00980	3.61e-46	-	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecE/Sec61-gamma subunits of protein translocation complex
FICKLOND_00981	6.29e-135	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
FICKLOND_00982	2.58e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FICKLOND_00983	1.74e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
FICKLOND_00984	9.92e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FICKLOND_00985	3.69e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
FICKLOND_00987	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FICKLOND_00990	0.0	-	-	-	V	-	-	-	MatE
FICKLOND_00991	4.33e-161	menG	2.1.1.163, 2.1.1.201	-	Q	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	ubiE/COQ5 methyltransferase family
FICKLOND_00995	7.53e-201	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FICKLOND_00996	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FICKLOND_00997	1.3e-210	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
FICKLOND_00998	3.95e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FICKLOND_01000	1.37e-306	-	-	-	E	ko:K03310	-	ko00000	Sodium:alanine symporter family
FICKLOND_01002	2.43e-95	-	-	-	K	-	-	-	-acetyltransferase
FICKLOND_01003	8.6e-222	-	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Glutaminase
FICKLOND_01004	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
FICKLOND_01005	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
FICKLOND_01006	2.79e-114	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
FICKLOND_01009	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Prolyl-tRNA synthetase, C-terminal
FICKLOND_01010	2.04e-158	-	-	-	S	-	-	-	Peptidase family M50
FICKLOND_01012	2.27e-215	-	-	-	JM	-	-	-	Nucleotidyl transferase
FICKLOND_01013	8.25e-273	-	-	-	S	-	-	-	Phosphotransferase enzyme family
FICKLOND_01014	1.01e-222	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
FICKLOND_01016	0.0	-	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
FICKLOND_01017	5.87e-296	-	-	-	-	-	-	-	-
FICKLOND_01018	0.0	-	-	-	-	-	-	-	-
FICKLOND_01019	1.03e-138	mntP	-	-	P	-	-	-	manganese ion transmembrane transporter activity
FICKLOND_01021	4.17e-190	-	-	-	S	-	-	-	Phenazine biosynthesis-like protein
FICKLOND_01022	9.46e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
FICKLOND_01023	0.0	-	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, Activator interacting domain (AID)
FICKLOND_01024	5.48e-273	ycaD	-	-	EGP	ko:K08219	-	ko00000,ko02000	Major facilitator Superfamily
FICKLOND_01025	4.27e-225	-	3.4.11.10, 3.4.11.6	-	DZ	ko:K19701	-	ko00000,ko01000,ko01002	aminopeptidase activity
FICKLOND_01026	1.16e-287	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
FICKLOND_01027	0.0	-	-	-	S	-	-	-	inositol 2-dehydrogenase activity
FICKLOND_01029	6.73e-286	-	3.6.4.13	-	L	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	helicase superfamily c-terminal domain
FICKLOND_01031	3.6e-145	-	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
FICKLOND_01032	0.0	-	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FICKLOND_01033	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
FICKLOND_01034	9.77e-278	-	4.2.1.51, 5.4.99.5	-	E	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
FICKLOND_01035	3.72e-237	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
FICKLOND_01036	1.91e-191	-	-	-	S	-	-	-	NIF3 (NGG1p interacting factor 3)
FICKLOND_01037	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
FICKLOND_01038	0.0	-	-	-	N	-	-	-	ABC-type uncharacterized transport system
FICKLOND_01039	1.01e-182	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
FICKLOND_01040	1.09e-223	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
FICKLOND_01041	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FICKLOND_01042	2.38e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	nUDIX hydrolase
FICKLOND_01044	1.52e-40	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
FICKLOND_01045	2.16e-21	traC	-	-	P	-	-	-	DNA integration
FICKLOND_01046	1.49e-06	-	-	-	L	ko:K07505	-	ko00000	Primase C terminal 2 (PriCT-2)
FICKLOND_01047	7.09e-65	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
FICKLOND_01049	1.17e-12	-	2.1.1.37, 3.1.21.4	-	L	ko:K00558,ko:K01155	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	DNA (cytosine-5-)-methyltransferase activity
FICKLOND_01050	1.01e-23	-	-	-	-	-	-	-	-
FICKLOND_01058	2.74e-06	-	-	-	-	-	-	-	-
FICKLOND_01060	1.07e-10	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
FICKLOND_01061	5.17e-26	-	-	-	S	-	-	-	chitin catabolic process
FICKLOND_01066	5.94e-235	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
FICKLOND_01067	3.78e-248	-	-	-	M	-	-	-	Glycosyl transferase, family 2
FICKLOND_01068	1.27e-207	MA20_42350	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyl transferase, family 2
FICKLOND_01069	1.83e-282	-	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	FAD binding domain
FICKLOND_01070	9.5e-239	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FICKLOND_01071	3.4e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
FICKLOND_01075	1.09e-09	-	-	-	K	-	-	-	transcriptional
FICKLOND_01081	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
FICKLOND_01082	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR/Asp-box repeat
FICKLOND_01083	8.38e-276	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
FICKLOND_01084	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	exo-alpha-(2->6)-sialidase activity
FICKLOND_01086	2.28e-79	-	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
FICKLOND_01087	0.0	-	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	NAD synthase
FICKLOND_01088	7.18e-182	-	-	-	Q	-	-	-	methyltransferase activity
FICKLOND_01090	3.15e-137	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
FICKLOND_01091	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
FICKLOND_01092	6.13e-194	-	-	-	-	-	-	-	-
FICKLOND_01093	4.91e-121	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	G/U mismatch-specific uracil-DNA glycosylase activity
FICKLOND_01094	3.12e-224	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
FICKLOND_01095	2.88e-116	hisI	3.5.4.19	-	E	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-AMP cyclohydrolase
FICKLOND_01096	1.18e-170	-	-	-	S	ko:K05807	-	ko00000,ko02000	Outer membrane lipoprotein
FICKLOND_01097	7.51e-116	-	-	-	S	-	-	-	Lipopolysaccharide-assembly
FICKLOND_01098	4.14e-164	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Tetrapyrrole (Corrin/Porphyrin) Methylases
FICKLOND_01099	3.23e-182	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
FICKLOND_01100	2.72e-18	-	-	-	-	-	-	-	-
FICKLOND_01101	0.0	-	-	-	P	ko:K07221	-	ko00000,ko02000	Phosphate-selective porin O and P
FICKLOND_01102	3.86e-162	rnc	3.1.26.3	-	K	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
FICKLOND_01103	1.53e-120	actI	1.5.1.36	-	S	ko:K00484	ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220	ko00000,ko00001,ko01000	FMN binding
FICKLOND_01104	1.57e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FICKLOND_01105	8.17e-147	-	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
FICKLOND_01106	2.3e-142	-	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Cytidylate kinase
FICKLOND_01107	0.0	-	-	-	I	-	-	-	Acetyltransferase (GNAT) domain
FICKLOND_01108	1.21e-209	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FICKLOND_01109	4.34e-202	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
FICKLOND_01110	0.0	-	-	-	GK	-	-	-	carbohydrate kinase activity
FICKLOND_01111	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
FICKLOND_01113	2.66e-290	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FICKLOND_01114	3.36e-130	-	-	-	D	ko:K06287	-	ko00000	Maf-like protein
FICKLOND_01115	0.0	-	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
FICKLOND_01117	1.6e-76	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
FICKLOND_01122	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
FICKLOND_01123	3.5e-121	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
FICKLOND_01124	0.0	-	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase / GMP reductase domain
FICKLOND_01125	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	GMP synthase C terminal domain
FICKLOND_01126	6.45e-138	-	-	-	S	-	-	-	Maltose acetyltransferase
FICKLOND_01127	6.43e-153	ppaX_1	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
FICKLOND_01128	1.41e-30	-	-	-	S	-	-	-	NYN domain
FICKLOND_01129	1.02e-232	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
FICKLOND_01130	3.17e-129	-	-	-	-	-	-	-	-
FICKLOND_01131	6.87e-256	-	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FICKLOND_01132	3.3e-151	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
FICKLOND_01133	3.86e-76	-	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
FICKLOND_01134	9e-65	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FICKLOND_01135	5.8e-219	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
FICKLOND_01136	9.36e-171	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FICKLOND_01137	2.08e-241	-	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
FICKLOND_01139	1.03e-207	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
FICKLOND_01140	9.15e-244	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
FICKLOND_01141	6.79e-249	-	-	-	S	-	-	-	Glycosyltransferase like family 2
FICKLOND_01142	5.48e-235	-	-	GT9	M	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	ADP-heptose-lipopolysaccharide heptosyltransferase activity
FICKLOND_01143	2.26e-245	-	5.1.3.20	-	M	ko:K03274	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-beta hydroxysteroid dehydrogenase/isomerase family
FICKLOND_01144	2.74e-288	-	-	-	M	-	-	-	Glycosyltransferase like family 2
FICKLOND_01145	1.03e-204	-	-	-	-	-	-	-	-
FICKLOND_01146	5.02e-310	-	-	-	M	-	-	-	Glycosyl transferases group 1
FICKLOND_01147	2.57e-253	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
FICKLOND_01148	0.0	-	-	-	I	-	-	-	Acyltransferase family
FICKLOND_01149	2.8e-258	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
FICKLOND_01151	0.0	-	-	-	P	-	-	-	Citrate transporter
FICKLOND_01153	6.56e-112	-	-	-	S	ko:K08999	-	ko00000	Bifunctional nuclease
FICKLOND_01154	5.58e-110	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
FICKLOND_01155	0.0	-	-	-	E	-	-	-	Transglutaminase-like
FICKLOND_01156	8.77e-158	-	-	-	C	-	-	-	Nitroreductase family
FICKLOND_01157	0.0	-	3.2.1.23	-	G	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
FICKLOND_01158	4.57e-181	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
FICKLOND_01159	5.6e-241	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
FICKLOND_01160	1.41e-289	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
FICKLOND_01161	9.75e-316	hsrA	-	-	EGP	-	-	-	Major facilitator Superfamily
FICKLOND_01162	7.17e-104	yciA	-	-	I	ko:K10806	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	acyl-coa hydrolase
FICKLOND_01165	3.1e-207	-	-	-	IQ	-	-	-	KR domain
FICKLOND_01166	6.84e-248	-	-	-	M	-	-	-	Alginate lyase
FICKLOND_01167	9.25e-106	-	-	-	L	-	-	-	Staphylococcal nuclease homologues
FICKLOND_01170	3.45e-121	-	-	-	K	-	-	-	ParB domain protein nuclease
FICKLOND_01171	0.0	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase
FICKLOND_01174	2.64e-267	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
FICKLOND_01175	2.63e-269	-	-	-	E	-	-	-	FAD dependent oxidoreductase
FICKLOND_01176	1.21e-210	-	-	-	S	-	-	-	Rhomboid family
FICKLOND_01177	0.0	-	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
FICKLOND_01178	5.93e-05	-	-	-	-	-	-	-	-
FICKLOND_01179	0.0	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
FICKLOND_01180	1.32e-313	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
FICKLOND_01181	1.71e-264	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
FICKLOND_01183	8.62e-102	-	-	-	-	-	-	-	-
FICKLOND_01184	8.08e-236	gpsA	1.1.1.94	-	C	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
FICKLOND_01185	4.34e-152	-	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Glycerol-3-phosphate acyltransferase
FICKLOND_01186	1.02e-187	pppL	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	protein serine/threonine phosphatase activity
FICKLOND_01187	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
FICKLOND_01189	0.0	-	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FICKLOND_01190	1.32e-101	manC	-	-	S	-	-	-	Cupin domain
FICKLOND_01191	3.2e-70	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
FICKLOND_01192	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
FICKLOND_01193	3.14e-179	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
FICKLOND_01195	0.0	-	-	-	P	-	-	-	Cation transport protein
FICKLOND_01196	3.52e-161	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
FICKLOND_01197	0.0	-	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Oligonucleotide/oligosaccharide-binding (OB)-fold
FICKLOND_01198	1.18e-109	-	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
FICKLOND_01199	0.0	-	-	-	O	-	-	-	Trypsin
FICKLOND_01200	4.27e-273	-	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
FICKLOND_01201	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
FICKLOND_01202	9.16e-266	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	RibD C-terminal domain
FICKLOND_01203	9.86e-158	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
FICKLOND_01205	1.02e-258	-	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
FICKLOND_01207	7.09e-251	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
FICKLOND_01208	0.0	-	-	-	V	-	-	-	MatE
FICKLOND_01209	3.05e-180	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
FICKLOND_01210	2.63e-84	-	-	-	M	-	-	-	Lysin motif
FICKLOND_01211	4.37e-203	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
FICKLOND_01212	1.78e-266	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2219)
FICKLOND_01213	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
FICKLOND_01214	2.66e-06	-	-	-	-	-	-	-	-
FICKLOND_01216	0.0	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
FICKLOND_01217	2.4e-167	-	-	-	T	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
FICKLOND_01219	0.0	-	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FICKLOND_01220	0.0	-	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FICKLOND_01221	6.76e-131	-	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FICKLOND_01222	7.36e-56	-	-	-	S	-	-	-	PFAM Cupin 2 conserved barrel domain protein
FICKLOND_01223	3.39e-92	-	-	-	L	-	-	-	IMG reference gene
FICKLOND_01224	1.66e-33	-	-	-	S	-	-	-	conserved domain
FICKLOND_01225	1.05e-15	-	-	-	M	-	-	-	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FICKLOND_01227	1.29e-230	-	-	-	K	-	-	-	DNA-binding transcription factor activity
FICKLOND_01229	0.0	-	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	C-terminal, D2-small domain, of ClpB protein
FICKLOND_01230	3.53e-255	-	-	-	S	-	-	-	Putative S-adenosyl-L-methionine-dependent methyltransferase
FICKLOND_01231	1.38e-226	-	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate synthetase A protein
FICKLOND_01232	1.26e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FICKLOND_01233	0.0	-	3.2.1.52	GH20	G	ko:K01207,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko01501,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map01501,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
FICKLOND_01235	5.32e-108	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
FICKLOND_01237	0.0	-	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
FICKLOND_01238	2.57e-251	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
FICKLOND_01239	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FICKLOND_01243	5.93e-261	-	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
FICKLOND_01244	8.43e-155	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
FICKLOND_01245	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, domain 2
FICKLOND_01246	1.76e-179	-	-	-	M	-	-	-	NLP P60 protein
FICKLOND_01247	6.77e-87	-	-	-	S	ko:K09940	-	ko00000	Domain of unknown function (DUF4870)
FICKLOND_01249	4.94e-75	-	-	-	C	ko:K04651	-	ko00000,ko03110	Hydrogenase/urease nickel incorporation, metallochaperone, hypA
FICKLOND_01250	3.4e-126	-	-	-	C	ko:K03605	-	ko00000,ko01000,ko01002	Hydrogenase maturation protease
FICKLOND_01251	6.49e-290	hyaC	-	-	C	ko:K03620	ko02020,map02020	ko00000,ko00001	Prokaryotic cytochrome b561
FICKLOND_01252	0.0	-	1.12.99.6	-	C	ko:K06281	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nickel-dependent hydrogenase
FICKLOND_01253	6.94e-298	-	1.12.99.6	-	C	ko:K06282	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	NiFe/NiFeSe hydrogenase small subunit C-terminal
FICKLOND_01254	0.0	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
FICKLOND_01256	9.83e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FICKLOND_01257	0.0	-	-	-	H	-	-	-	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FICKLOND_01258	0.0	-	3.4.24.3	-	NU	ko:K01387	-	ko00000,ko01000,ko01002,ko02042	translation initiation factor activity
FICKLOND_01259	0.0	-	-	-	M	-	-	-	Transglycosylase
FICKLOND_01260	2.63e-135	-	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	Peptidyl-tRNA hydrolase
FICKLOND_01261	4.58e-215	-	-	-	S	-	-	-	Protein of unknown function DUF58
FICKLOND_01262	3.82e-231	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
FICKLOND_01263	2.46e-216	-	3.5.1.53	-	K	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
FICKLOND_01265	2.36e-273	-	-	-	E	-	-	-	Alcohol dehydrogenase GroES-like domain
FICKLOND_01266	2.56e-309	-	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Seryl-tRNA synthetase N-terminal domain
FICKLOND_01268	1.47e-19	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
FICKLOND_01273	1.08e-266	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
FICKLOND_01274	0.0	yidC	-	-	O	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	serine-type endopeptidase activity
FICKLOND_01275	3.06e-157	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
FICKLOND_01276	2.76e-129	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FICKLOND_01277	1.02e-256	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
FICKLOND_01278	4.86e-230	exsH	3.2.1.178, 3.2.1.18, 3.2.1.52	GH16,GH20,GH33	G	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	xyloglucan:xyloglucosyl transferase activity
FICKLOND_01279	0.0	-	-	-	I	ko:K06889,ko:K09914	-	ko00000	PFAM Prenyltransferase squalene oxidase
FICKLOND_01280	4.24e-314	-	1.1.1.40	-	C	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Malic enzyme, NAD binding domain
FICKLOND_01283	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FICKLOND_01284	0.0	-	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
FICKLOND_01285	2.14e-300	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
FICKLOND_01286	1.19e-92	-	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
FICKLOND_01287	6.17e-284	-	-	-	S	-	-	-	very-long-chain-acyl-CoA dehydrogenase activity
FICKLOND_01289	1.32e-296	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
FICKLOND_01290	1.91e-147	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
FICKLOND_01291	3.82e-231	-	-	-	C	-	-	-	Nitroreductase family
FICKLOND_01292	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
FICKLOND_01293	3.13e-123	-	-	-	C	-	-	-	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FICKLOND_01294	1.58e-25	-	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
FICKLOND_01295	6.17e-237	-	-	-	M	-	-	-	Glycosyl transferase, family 2
FICKLOND_01296	3.34e-208	-	-	-	M	-	-	-	PFAM glycosyl transferase family 2
FICKLOND_01297	2.67e-113	-	-	-	S	ko:K03818	-	ko00000,ko01000	maltose O-acetyltransferase activity
FICKLOND_01298	0.0	-	-	-	-	-	-	-	-
FICKLOND_01299	3.29e-279	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
FICKLOND_01300	5.24e-279	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
FICKLOND_01301	1.32e-249	-	-	-	M	-	-	-	Glycosyl transferases group 1
FICKLOND_01302	2.42e-198	-	-	-	S	-	-	-	Glycosyl transferase family 11
FICKLOND_01303	9.16e-264	-	-	-	M	ko:K02847,ko:K13009	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
FICKLOND_01304	1.71e-241	-	-	-	-	-	-	-	-
FICKLOND_01305	9.22e-290	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
FICKLOND_01306	8.15e-285	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
FICKLOND_01307	3.33e-289	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
FICKLOND_01308	1.77e-191	wbyL	-	GT2	M	ko:K13002	-	ko00000,ko01000,ko01003,ko01005	transferase activity, transferring glycosyl groups
FICKLOND_01309	6.88e-176	-	-	-	M	-	-	-	Bacterial sugar transferase
FICKLOND_01310	9.48e-165	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	protein tyrosine phosphatase activity
FICKLOND_01311	0.0	gumC	-	-	DM	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	PFAM lipopolysaccharide biosynthesis protein
FICKLOND_01312	5.68e-180	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	polysaccharide export
FICKLOND_01313	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk_gamma
FICKLOND_01315	7.6e-145	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FICKLOND_01316	1.08e-136	rbr	-	-	C	-	-	-	Rubrerythrin
FICKLOND_01317	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
FICKLOND_01319	0.0	-	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Catalase
FICKLOND_01320	1.01e-45	-	-	-	S	-	-	-	R3H domain
FICKLOND_01322	0.0	-	1.2.1.88, 1.5.5.2	-	CE	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko03000	Proline dehydrogenase
FICKLOND_01323	7.62e-284	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
FICKLOND_01324	3.05e-116	csd2	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein, Csd2 family
FICKLOND_01325	1.29e-133	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
FICKLOND_01326	6.97e-107	-	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
FICKLOND_01327	1.07e-83	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	DEAD-like helicases superfamily
FICKLOND_01328	3.47e-59	cas4	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	crispr-associated protein cas4
FICKLOND_01329	8.36e-119	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FICKLOND_01330	5.87e-32	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FICKLOND_01342	0.0	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
FICKLOND_01344	1.04e-109	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FICKLOND_01345	8.76e-126	-	-	-	-	-	-	-	-
FICKLOND_01346	0.0	-	-	-	U	ko:K03321	-	ko00000,ko02000	Sulfate permease family
FICKLOND_01347	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase C-terminal
FICKLOND_01348	1.45e-162	-	-	-	S	-	-	-	SWIM zinc finger
FICKLOND_01349	0.0	-	-	-	-	-	-	-	-
FICKLOND_01350	1.73e-307	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
FICKLOND_01351	1.47e-204	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FICKLOND_01352	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
FICKLOND_01353	3.29e-258	-	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
FICKLOND_01354	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
FICKLOND_01355	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FICKLOND_01356	3.31e-303	-	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	tRNA (Uracil-5-)-methyltransferase
FICKLOND_01359	0.0	-	-	-	-	-	-	-	-
FICKLOND_01360	7.36e-55	himA	-	-	L	ko:K03530,ko:K04764,ko:K05788	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
FICKLOND_01361	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
FICKLOND_01362	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
FICKLOND_01363	2.68e-110	-	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
FICKLOND_01364	0.0	-	-	-	T	-	-	-	Histidine kinase
FICKLOND_01365	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
FICKLOND_01366	1.07e-188	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
FICKLOND_01367	3.8e-43	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	CTP reductase activity
FICKLOND_01368	0.0	-	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
FICKLOND_01369	0.0	-	-	-	M	-	-	-	Glycosyl Hydrolase Family 88
FICKLOND_01370	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1705)
FICKLOND_01372	1.96e-121	ngr	-	-	C	-	-	-	Rubrerythrin
FICKLOND_01374	8.88e-268	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
FICKLOND_01375	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
FICKLOND_01376	4.06e-287	-	-	-	EGP	-	-	-	Major facilitator Superfamily
FICKLOND_01377	2.05e-277	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
FICKLOND_01378	3.06e-85	-	-	-	M	ko:K03282	-	ko00000,ko02000	Large-conductance mechanosensitive channel, MscL
FICKLOND_01379	1.95e-312	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
FICKLOND_01380	1.2e-105	-	-	-	S	-	-	-	ACT domain protein
FICKLOND_01381	9.29e-132	-	-	-	J	ko:K02356	-	ko00000,ko03012	Elongation factor P (EF-P) OB domain
FICKLOND_01382	1.16e-244	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
FICKLOND_01383	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
FICKLOND_01384	0.0	-	-	-	L	ko:K03631	-	ko00000,ko03400	RecF/RecN/SMC N terminal domain
FICKLOND_01385	3.05e-189	-	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Metallo-beta-lactamase superfamily
FICKLOND_01386	5.06e-192	-	-	-	M	-	-	-	Glycosyl transferase WecB/TagA/CpsF family
FICKLOND_01387	2.28e-170	yyaQ	-	-	V	-	-	-	Protein conserved in bacteria
FICKLOND_01388	4.67e-91	-	-	-	-	-	-	-	-
FICKLOND_01391	4.72e-206	-	-	-	S	ko:K09949	-	ko00000	Protein of unknown function (DUF1009)
FICKLOND_01392	1.63e-298	-	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
FICKLOND_01393	9.47e-236	-	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
FICKLOND_01394	1.13e-221	-	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
FICKLOND_01395	2.52e-197	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FICKLOND_01396	1e-242	-	-	-	M	ko:K18094	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	Biotin-lipoyl like
FICKLOND_01397	0.0	-	-	-	V	ko:K18095	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	AcrB/AcrD/AcrF family
FICKLOND_01398	0.0	-	-	-	S	-	-	-	pathogenesis
FICKLOND_01399	2.1e-99	-	-	-	S	-	-	-	peptidase
FICKLOND_01400	5.18e-172	-	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
FICKLOND_01401	2.24e-101	-	-	-	S	-	-	-	peptidase
FICKLOND_01402	0.0	-	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase HemD
FICKLOND_01403	4.53e-100	-	-	-	-	-	-	-	-
FICKLOND_01404	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Bacterial DNA topoisomeraes I ATP-binding domain
FICKLOND_01408	8.8e-169	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
FICKLOND_01409	0.0	-	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
FICKLOND_01410	2.57e-133	-	-	-	D	-	-	-	ErfK ybiS ycfS ynhG family protein
FICKLOND_01412	2.51e-284	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FICKLOND_01414	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
FICKLOND_01415	3.36e-271	-	-	-	S	-	-	-	tRNA-splicing ligase RtcB
FICKLOND_01416	4.55e-213	-	-	-	K	-	-	-	LysR substrate binding domain
FICKLOND_01417	3.53e-295	-	-	-	EGP	-	-	-	Major facilitator Superfamily
FICKLOND_01419	7.1e-130	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
FICKLOND_01420	6.52e-75	-	-	-	L	-	-	-	Cupin 2, conserved barrel domain protein
FICKLOND_01421	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
FICKLOND_01423	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Collagenase
FICKLOND_01424	1.53e-286	-	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
FICKLOND_01426	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
FICKLOND_01427	0.0	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 Helicase protein
FICKLOND_01428	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
FICKLOND_01429	1.77e-124	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
FICKLOND_01430	4.9e-207	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FICKLOND_01431	1.53e-47	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S L24/mitochondrial 39S L24
FICKLOND_01432	5.36e-138	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FICKLOND_01433	4.08e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FICKLOND_01434	2.25e-105	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FICKLOND_01435	2.38e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FICKLOND_01436	6.75e-29	-	-	-	I	-	-	-	PFAM biotin lipoyl attachment domain-containing protein
FICKLOND_01437	0.0	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
FICKLOND_01438	9.48e-192	-	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
FICKLOND_01439	0.0	-	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
FICKLOND_01441	9.14e-204	-	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FICKLOND_01442	7.56e-271	-	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
FICKLOND_01443	1.13e-228	-	2.7.1.11	-	G	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Phosphofructokinase
FICKLOND_01444	9.11e-182	-	-	-	L	ko:K10800	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	uracil-dna glycosylase
FICKLOND_01445	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FICKLOND_01446	0.0	poxB	1.2.3.3, 1.2.5.1	-	EH	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
FICKLOND_01449	0.0	-	-	-	G	-	-	-	alpha-galactosidase
FICKLOND_01451	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
FICKLOND_01452	2.76e-267	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FICKLOND_01453	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FICKLOND_01454	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
FICKLOND_01456	1.23e-177	-	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
FICKLOND_01458	7.23e-164	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
FICKLOND_01461	0.0	-	-	-	L	-	-	-	DNA restriction-modification system
FICKLOND_01465	3.92e-115	-	-	-	-	-	-	-	-
FICKLOND_01466	1.62e-184	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
FICKLOND_01468	2.31e-162	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
FICKLOND_01469	4.85e-260	tdh	1.1.1.103	-	E	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
FICKLOND_01470	0.0	-	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Carbohydrate phosphorylase
FICKLOND_01471	8.34e-180	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
FICKLOND_01472	1.55e-83	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	ArsC family
FICKLOND_01473	0.0	-	-	-	J	ko:K07576	-	ko00000	Beta-Casp domain
FICKLOND_01474	8.48e-56	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
FICKLOND_01475	3.94e-243	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
FICKLOND_01476	1.21e-238	-	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
FICKLOND_01477	2.05e-28	-	-	-	-	-	-	-	-
FICKLOND_01478	8.07e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	tRNA (Guanine-1)-methyltransferase
FICKLOND_01479	8.8e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FICKLOND_01480	1.66e-87	-	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
FICKLOND_01481	0.0	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
FICKLOND_01482	1.26e-136	-	-	-	C	-	-	-	Nitroreductase family
FICKLOND_01483	1.23e-110	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
FICKLOND_01486	6.51e-19	-	-	-	S	-	-	-	Phage Tail Collar Domain
FICKLOND_01487	1.73e-106	-	-	-	S	-	-	-	Glycosyl hydrolase 108
FICKLOND_01491	1.56e-07	-	-	-	D	-	-	-	nuclear chromosome segregation
FICKLOND_01492	5.77e-40	-	-	-	S	-	-	-	Phage tail protein (Tail_P2_I)
FICKLOND_01493	2.68e-56	-	-	-	S	-	-	-	Baseplate J-like protein
FICKLOND_01494	1.08e-12	-	-	-	-	-	-	-	-
FICKLOND_01497	5.85e-62	-	-	-	S	ko:K06905	-	ko00000	COG3500 Phage protein D
FICKLOND_01498	4.95e-18	-	-	-	S	-	-	-	Phage Tail Protein X
FICKLOND_01499	3.41e-58	-	-	-	D	-	-	-	phage tail tape measure protein
FICKLOND_01503	4.11e-203	-	-	-	S	ko:K06907	-	ko00000	COG3497 Phage tail sheath protein FI
FICKLOND_01505	1.05e-16	-	-	-	-	-	-	-	-
FICKLOND_01507	2.69e-84	-	-	-	S	-	-	-	Phage major capsid protein E
FICKLOND_01508	3.83e-96	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Clp protease
FICKLOND_01509	1.12e-159	-	-	-	S	-	-	-	Phage portal protein, lambda family
FICKLOND_01511	2.29e-233	-	-	-	S	-	-	-	Phage terminase large subunit (GpA)
FICKLOND_01515	8.93e-141	-	-	-	K	ko:K12055	-	ko00000,ko02044	chromosome segregation
FICKLOND_01516	6.3e-38	-	-	-	KL	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
FICKLOND_01519	5.78e-63	-	-	-	L	-	-	-	D12 class N6 adenine-specific DNA methyltransferase
FICKLOND_01520	1.6e-23	-	-	-	EH	-	-	-	sulfate reduction
FICKLOND_01528	4.52e-18	-	-	-	L	-	-	-	YqaJ-like viral recombinase domain
FICKLOND_01529	4.32e-06	Z012_11975	-	-	M	-	-	-	protein involved in exopolysaccharide biosynthesis
FICKLOND_01530	7.5e-72	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
FICKLOND_01533	3.2e-21	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
FICKLOND_01543	7.29e-211	-	-	-	M	-	-	-	Peptidase family M23
FICKLOND_01544	5.03e-229	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
FICKLOND_01545	4.13e-183	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
FICKLOND_01546	4.21e-121	-	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
FICKLOND_01547	4.14e-175	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate reductase, N-terminus
FICKLOND_01548	1.02e-203	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
FICKLOND_01550	2.33e-91	mltD	-	CBM50	M	ko:K08307,ko:K12204,ko:K19224	-	ko00000,ko01000,ko01002,ko01011,ko02044	LysM domain
FICKLOND_01551	1.33e-277	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Cell cycle protein
FICKLOND_01552	3.91e-267	-	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FICKLOND_01553	0.0	murB	-	-	M	-	-	-	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
FICKLOND_01554	4.13e-228	ddl	6.3.2.4	-	M	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	D-ala D-ala ligase N-terminus
FICKLOND_01555	1.8e-216	-	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	POTRA domain, FtsQ-type
FICKLOND_01556	1.15e-238	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FICKLOND_01557	1.92e-238	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
FICKLOND_01558	7.14e-141	-	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
FICKLOND_01559	0.0	-	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase family (aconitate hydratase)
FICKLOND_01560	1.53e-146	-	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
FICKLOND_01561	4.99e-274	-	-	-	-	-	-	-	-
FICKLOND_01562	0.0	-	-	-	O	-	-	-	Trypsin
FICKLOND_01563	0.0	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
FICKLOND_01564	4.53e-284	-	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate synthase
FICKLOND_01566	2.65e-174	-	-	-	E	-	-	-	ATPases associated with a variety of cellular activities
FICKLOND_01567	7.15e-199	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FICKLOND_01568	5.88e-163	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S2
FICKLOND_01569	9.04e-171	cbiX	4.99.1.3	-	S	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	sirohydrochlorin cobaltochelatase activity
FICKLOND_01570	6.68e-198	-	2.5.1.55	-	M	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	DAHP synthetase I family
FICKLOND_01573	6.31e-171	-	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
FICKLOND_01574	6.55e-221	-	-	-	E	-	-	-	Phosphoserine phosphatase
FICKLOND_01575	0.0	-	6.3.2.45	-	M	ko:K02558	-	ko00000,ko01000	Mur ligase family, catalytic domain
FICKLOND_01576	7.79e-301	-	-	-	M	-	-	-	OmpA family
FICKLOND_01577	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
FICKLOND_01578	9.27e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
FICKLOND_01579	5.33e-114	ywrF	-	-	S	-	-	-	FMN binding
FICKLOND_01580	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
FICKLOND_01581	0.0	-	-	-	T	-	-	-	pathogenesis
FICKLOND_01583	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
FICKLOND_01584	5.48e-296	-	-	-	-	-	-	-	-
FICKLOND_01585	5.12e-71	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
FICKLOND_01587	1.1e-160	-	-	-	S	-	-	-	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FICKLOND_01588	9.82e-262	-	-	-	M	ko:K02022	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FICKLOND_01589	8.42e-302	-	4.2.1.129, 5.4.99.17, 5.5.1.16	-	I	ko:K06045,ko:K17811	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
FICKLOND_01590	0.0	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
FICKLOND_01591	4.36e-235	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
FICKLOND_01594	1.12e-214	-	-	-	K	-	-	-	LysR substrate binding domain
FICKLOND_01595	5.45e-234	-	-	-	S	-	-	-	Conserved hypothetical protein 698
FICKLOND_01596	7.38e-252	-	-	-	E	-	-	-	Aminotransferase class-V
FICKLOND_01597	2.56e-312	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
FICKLOND_01598	0.0	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
FICKLOND_01599	2.2e-173	-	2.7.13.3	-	Q	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Transposase
FICKLOND_01600	6.66e-167	-	4.3.99.3	-	O	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
FICKLOND_01601	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FICKLOND_01602	1.67e-172	-	-	-	K	-	-	-	Transcriptional regulator
FICKLOND_01603	0.0	-	-	-	P	-	-	-	Dimerisation domain of Zinc Transporter
FICKLOND_01604	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
FICKLOND_01606	1.93e-242	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FICKLOND_01607	2.17e-201	-	-	-	S	-	-	-	SigmaW regulon antibacterial
FICKLOND_01609	4.07e-173	-	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiG
FICKLOND_01610	3.27e-294	-	-	-	E	-	-	-	Amino acid permease
FICKLOND_01611	3.28e-155	gph	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
FICKLOND_01612	6.62e-257	-	-	-	S	ko:K11744	-	ko00000	AI-2E family transporter
FICKLOND_01613	2.39e-314	-	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
FICKLOND_01614	7.64e-235	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
FICKLOND_01615	0.0	-	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
FICKLOND_01616	3.48e-213	-	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FICKLOND_01617	5.11e-222	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
FICKLOND_01618	1.56e-127	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FICKLOND_01619	7.86e-138	-	-	-	T	-	-	-	histone H2A K63-linked ubiquitination
FICKLOND_01621	3.23e-253	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FICKLOND_01622	2.84e-286	-	-	-	S	-	-	-	Phosphotransferase enzyme family
FICKLOND_01623	1.89e-255	-	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
FICKLOND_01624	4.88e-265	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
FICKLOND_01628	0.0	-	-	-	G	-	-	-	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain
FICKLOND_01629	0.000651	-	-	-	-	-	-	-	-
FICKLOND_01630	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
FICKLOND_01631	5.46e-189	-	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
FICKLOND_01633	0.0	-	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	DHHA2
FICKLOND_01634	1.89e-253	-	-	-	N	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease Exonuclease Phosphatase
FICKLOND_01635	8.25e-63	-	-	-	L	ko:K09747	-	ko00000	YbaB/EbfC DNA-binding family
FICKLOND_01636	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FICKLOND_01638	4.03e-174	-	-	-	D	-	-	-	Phage-related minor tail protein
FICKLOND_01640	1.69e-174	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
FICKLOND_01641	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FICKLOND_01642	6.12e-40	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FICKLOND_01643	2.79e-97	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FICKLOND_01644	1.67e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S9/S16
FICKLOND_01645	1.27e-99	-	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Predicted SPOUT methyltransferase
FICKLOND_01646	0.0	-	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
FICKLOND_01647	6.34e-183	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
FICKLOND_01648	6.23e-97	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
FICKLOND_01649	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
FICKLOND_01650	0.0	-	-	-	M	-	-	-	PFAM glycosyl transferase family 51
FICKLOND_01651	6.64e-185	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
FICKLOND_01652	1.93e-117	ispF	4.6.1.12	-	I	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
FICKLOND_01653	1.29e-181	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
FICKLOND_01654	3.4e-229	-	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphomannose isomerase type I
FICKLOND_01655	1.11e-236	-	-	-	-	-	-	-	-
FICKLOND_01656	8.01e-294	-	-	-	C	-	-	-	Na+/H+ antiporter family
FICKLOND_01657	1.31e-268	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
FICKLOND_01658	6.96e-265	-	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FICKLOND_01659	3.11e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase small chain, CPSase domain
FICKLOND_01660	0.0	-	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
FICKLOND_01661	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
FICKLOND_01662	0.0	-	1.4.1.13, 1.4.1.14	-	E	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
FICKLOND_01663	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
FICKLOND_01664	1.09e-59	-	-	-	S	ko:K08998	-	ko00000	Haemolytic
FICKLOND_01665	4.9e-76	-	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	Ribonuclease P
FICKLOND_01666	1.1e-34	-	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
FICKLOND_01667	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
FICKLOND_01668	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
FICKLOND_01669	0.0	-	-	-	G	-	-	-	Trehalase
FICKLOND_01670	2.45e-211	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
FICKLOND_01671	3.45e-157	-	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
FICKLOND_01672	1.19e-199	-	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
FICKLOND_01673	2.63e-208	-	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Polyprenyl synthetase
FICKLOND_01674	9.55e-242	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FICKLOND_01676	1.11e-175	-	-	-	-	-	-	-	-
FICKLOND_01677	0.0	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
FICKLOND_01678	7.15e-221	-	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
FICKLOND_01679	2.11e-219	-	-	-	E	ko:K00612	-	ko00000,ko01000	lipolytic protein G-D-S-L family
FICKLOND_01680	1.14e-134	panZ	-	-	K	-	-	-	-acetyltransferase
FICKLOND_01686	1.2e-167	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
FICKLOND_01687	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
FICKLOND_01688	2.09e-207	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
FICKLOND_01689	2.46e-272	-	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
FICKLOND_01690	4.4e-138	-	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FICKLOND_01691	3.01e-188	-	5.2.1.8	-	O	ko:K03773	-	ko00000,ko01000,ko03110	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
FICKLOND_01699	4.52e-06	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
FICKLOND_01700	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FICKLOND_01701	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FICKLOND_01702	2.54e-132	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FICKLOND_01703	1.11e-262	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
FICKLOND_01704	6.41e-236	-	2.7.11.1	-	T	ko:K08884,ko:K12132,ko:K20333	ko02024,map02024	ko00000,ko00001,ko01000,ko01001	PFAM Formylglycine-generating sulfatase enzyme
FICKLOND_01706	7.19e-197	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
FICKLOND_01707	6e-142	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
FICKLOND_01708	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
FICKLOND_01709	1.02e-282	-	-	-	C	-	-	-	Aldo/keto reductase family
FICKLOND_01710	6.71e-90	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FICKLOND_01711	2e-259	-	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
FICKLOND_01712	1.78e-293	-	-	-	-	-	-	-	-
FICKLOND_01713	0.0	-	-	-	S	-	-	-	von Willebrand factor type A domain
FICKLOND_01714	0.0	-	-	-	S	-	-	-	Aerotolerance regulator N-terminal
FICKLOND_01715	4.72e-207	-	-	-	S	-	-	-	Protein of unknown function DUF58
FICKLOND_01716	0.0	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
FICKLOND_01717	1.78e-241	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
FICKLOND_01718	0.0	-	-	-	-	-	-	-	-
FICKLOND_01719	1.49e-237	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
FICKLOND_01720	4.24e-296	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
FICKLOND_01722	9.45e-239	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FICKLOND_01724	5.75e-202	-	-	-	O	-	-	-	stress-induced mitochondrial fusion
FICKLOND_01725	2.34e-207	-	-	-	S	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
FICKLOND_01726	8.5e-121	-	-	-	M	ko:K03098	-	ko00000,ko04147	Lipocalin-like domain
FICKLOND_01727	1.35e-236	-	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FICKLOND_01728	7.18e-190	-	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
FICKLOND_01729	8.26e-154	-	-	-	K	-	-	-	Transcriptional regulator
FICKLOND_01732	0.0	-	-	-	P	-	-	-	Sulfatase
FICKLOND_01733	1.04e-78	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
FICKLOND_01734	4.6e-305	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
FICKLOND_01735	0.0	-	-	-	E	-	-	-	Aminotransferase class I and II
FICKLOND_01736	7.5e-221	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
FICKLOND_01737	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha galactosidase A
FICKLOND_01738	1.04e-49	-	-	-	-	-	-	-	-
FICKLOND_01739	1.45e-55	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
FICKLOND_01741	9.07e-234	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
FICKLOND_01742	2.13e-96	-	-	-	L	ko:K07447	-	ko00000,ko01000	Likely ribonuclease with RNase H fold.
FICKLOND_01743	1.98e-258	-	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
FICKLOND_01744	1.06e-173	-	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FICKLOND_01745	0.0	-	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	TopoisomeraseII
FICKLOND_01746	1.84e-206	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
FICKLOND_01748	0.0	-	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	HELICc2
FICKLOND_01749	1.96e-178	cbiO	-	-	P	ko:K02006,ko:K02008,ko:K16784,ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase activity
FICKLOND_01750	2.82e-194	cbiQ	-	-	P	ko:K02007,ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transmembrane transporter activity
FICKLOND_01751	8.77e-239	cbiM	-	-	P	ko:K02007,ko:K02009,ko:K16915	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt ion transport
FICKLOND_01753	5e-19	-	-	-	S	-	-	-	Lipocalin-like
FICKLOND_01754	3.2e-209	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
FICKLOND_01755	1.81e-227	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
FICKLOND_01756	1.06e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L9, N-terminal domain
FICKLOND_01757	0.0	-	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT/IMPCHase bienzyme
FICKLOND_01758	5.64e-173	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FICKLOND_01759	9.05e-85	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	4'-phosphopantetheinyl transferase superfamily
FICKLOND_01761	0.0	pckG	4.1.1.32	-	C	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
FICKLOND_01762	4.02e-166	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
FICKLOND_01763	0.0	-	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	RecG wedge domain
FICKLOND_01765	0.0	-	-	-	C	ko:K00184	-	ko00000	4Fe-4S dicluster domain
FICKLOND_01766	2.16e-180	-	-	-	C	-	-	-	Cytochrome c7 and related cytochrome c
FICKLOND_01767	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
FICKLOND_01769	1.9e-256	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Iron-containing alcohol dehydrogenase
FICKLOND_01771	1.29e-187	-	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	2Fe-2S iron-sulfur cluster binding domain
FICKLOND_01772	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
FICKLOND_01773	4.83e-163	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	-
FICKLOND_01774	8.94e-56	-	-	-	-	-	-	-	-
FICKLOND_01775	1.43e-194	-	-	-	S	ko:K07051	-	ko00000	TatD related DNase
FICKLOND_01776	7.45e-49	XK27_09985	-	-	S	-	-	-	Protein of unknown function (DUF1232)
FICKLOND_01778	0.000576	-	-	-	-	-	-	-	-
FICKLOND_01780	1.43e-11	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
FICKLOND_01781	4.52e-307	-	-	-	C	-	-	-	Sulfatase-modifying factor enzyme 1
FICKLOND_01782	2.07e-169	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
FICKLOND_01784	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
FICKLOND_01785	2.98e-08	-	-	-	M	-	-	-	major outer membrane lipoprotein
FICKLOND_01787	4.21e-137	-	-	-	J	ko:K05808	-	ko00000,ko03009	Sigma 54 modulation/S30EA ribosomal protein C terminus
FICKLOND_01789	1.55e-24	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
FICKLOND_01790	2.29e-157	-	-	-	IQ	-	-	-	Short chain dehydrogenase
FICKLOND_01791	2.77e-308	-	-	-	C	-	-	-	Carboxymuconolactone decarboxylase family
FICKLOND_01792	2.9e-275	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
FICKLOND_01793	8.36e-186	-	-	-	S	-	-	-	Alpha/beta hydrolase family
FICKLOND_01794	6.03e-178	-	-	-	C	-	-	-	aldo keto reductase
FICKLOND_01795	1.05e-219	-	-	-	K	-	-	-	Transcriptional regulator
FICKLOND_01796	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
FICKLOND_01797	1.17e-304	-	-	-	C	-	-	-	4 iron, 4 sulfur cluster binding
FICKLOND_01798	1.88e-111	-	-	-	KT	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
FICKLOND_01799	2.59e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
FICKLOND_01800	1.96e-184	-	-	-	-	-	-	-	-
FICKLOND_01801	8.46e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
FICKLOND_01802	1.24e-51	-	-	-	-	-	-	-	-
FICKLOND_01804	1.46e-75	-	-	-	S	ko:K09954	-	ko00000	Putative quorum-sensing-regulated virulence factor
FICKLOND_01805	5.94e-178	-	4.2.99.20	-	I	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
FICKLOND_01806	1.39e-128	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
FICKLOND_01809	2.45e-216	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
FICKLOND_01810	6.71e-285	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
FICKLOND_01811	4.7e-57	-	-	-	S	ko:K06960	-	ko00000	KH domain
FICKLOND_01812	0.0	-	-	-	-	-	-	-	-
FICKLOND_01813	0.0	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	RNA cap guanine-N2 methyltransferase
FICKLOND_01814	3.06e-216	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
FICKLOND_01815	1.11e-239	-	4.2.1.113	-	M	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Mandelate Racemase Muconate Lactonizing
FICKLOND_01816	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
FICKLOND_01818	0.0	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
FICKLOND_01819	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
FICKLOND_01820	1.65e-102	-	-	-	G	-	-	-	single-species biofilm formation
FICKLOND_01821	7.97e-113	-	-	-	K	ko:K13640	-	ko00000,ko03000	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
FICKLOND_01822	4.8e-128	-	-	-	S	-	-	-	Flavodoxin-like fold
FICKLOND_01823	1.11e-188	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
FICKLOND_01824	7.2e-103	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
FICKLOND_01825	9.98e-129	-	-	-	C	-	-	-	FMN binding
FICKLOND_01826	8.47e-264	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
FICKLOND_01827	4.24e-270	-	-	-	C	-	-	-	Aldo/keto reductase family
FICKLOND_01828	2.97e-268	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
FICKLOND_01829	1.3e-205	-	-	-	S	-	-	-	Aldo/keto reductase family
FICKLOND_01830	3.45e-239	-	1.2.7.3	-	-	ko:K00176,ko:K07138	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	-
FICKLOND_01831	1.39e-301	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
FICKLOND_01832	2.66e-140	-	-	-	M	-	-	-	polygalacturonase activity
FICKLOND_01834	2.07e-195	-	-	-	KT	-	-	-	Peptidase S24-like
FICKLOND_01835	6.03e-292	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
FICKLOND_01839	3.8e-80	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
FICKLOND_01841	4.15e-129	-	-	-	S	-	-	-	Glycosyl hydrolase 108
FICKLOND_01847	2.62e-21	-	-	-	OU	-	-	-	Serine dehydrogenase proteinase
FICKLOND_01852	4.01e-71	-	-	-	S	-	-	-	Phage terminase large subunit (GpA)
FICKLOND_01854	7.88e-98	-	-	-	D	-	-	-	Filamentation induced by cAMP protein fic
FICKLOND_01865	1.04e-54	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
FICKLOND_01866	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FICKLOND_01867	0.0	-	-	-	M	ko:K02847,ko:K13009,ko:K16705	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
FICKLOND_01868	8.67e-85	-	-	-	S	-	-	-	Protein of unknown function, DUF488
FICKLOND_01869	3.43e-234	-	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Porphobilinogen deaminase, dipyromethane cofactor binding domain
FICKLOND_01870	1.07e-240	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Glutamyl-tRNAGlu reductase, N-terminal domain
FICKLOND_01871	1.02e-178	-	-	-	S	-	-	-	Cytochrome C assembly protein
FICKLOND_01872	3.84e-189	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Type I GTP cyclohydrolase folE2
FICKLOND_01873	4.52e-49	-	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S18
FICKLOND_01874	5.67e-33	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
FICKLOND_01875	1.46e-118	-	-	-	T	-	-	-	Prokaryotic dksA/traR C4-type zinc finger
FICKLOND_01876	5.9e-232	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
FICKLOND_01877	2.86e-245	sun	2.1.1.176, 2.1.1.178	-	J	ko:K03500,ko:K11392	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FICKLOND_01878	1.79e-122	-	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
FICKLOND_01879	2.34e-97	nudI	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	GDP-mannose mannosyl hydrolase activity
FICKLOND_01881	2.88e-283	-	-	-	M	ko:K02005	-	ko00000	HlyD family secretion protein
FICKLOND_01882	2.12e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
FICKLOND_01883	2.69e-310	-	-	-	V	-	-	-	MacB-like periplasmic core domain
FICKLOND_01884	8.19e-316	-	-	-	MU	-	-	-	Outer membrane efflux protein
FICKLOND_01885	1.57e-284	-	-	-	V	-	-	-	Beta-lactamase
FICKLOND_01886	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FICKLOND_01887	6.02e-283	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FICKLOND_01888	1.02e-94	-	-	-	K	-	-	-	DNA-binding transcription factor activity
FICKLOND_01889	2.06e-166	-	-	-	S	-	-	-	Uncharacterised protein family UPF0066
FICKLOND_01890	1.37e-306	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydro-orotase-like
FICKLOND_01891	1.55e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
FICKLOND_01892	1.15e-122	-	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Phosphoribosyl transferase domain
FICKLOND_01893	3.73e-90	-	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR carboxylase
FICKLOND_01895	0.0	-	-	-	H	ko:K07137	-	ko00000	5-formyltetrahydrofolate cyclo-ligase activity
FICKLOND_01896	6.45e-268	-	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
FICKLOND_01897	2.11e-89	-	-	-	-	-	-	-	-
FICKLOND_01898	0.0	rseP	3.4.21.116	-	M	ko:K06399,ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	metalloendopeptidase activity
FICKLOND_01899	1.7e-297	-	-	-	S	-	-	-	AI-2E family transporter
FICKLOND_01900	0.0	-	-	-	P	-	-	-	Domain of unknown function
FICKLOND_01902	1.52e-81	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
FICKLOND_01903	1.93e-313	-	-	-	G	-	-	-	cellulose 1,4-beta-cellobiosidase activity
FICKLOND_01904	4.02e-188	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
FICKLOND_01906	1.83e-74	-	-	-	-	-	-	-	-
FICKLOND_01907	0.0	-	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	DNA Topoisomerase IV
FICKLOND_01909	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
FICKLOND_01910	1.21e-241	-	-	-	E	ko:K07588	-	ko00000,ko01000	ArgK protein
FICKLOND_01911	1.82e-112	-	-	-	F	ko:K08311	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	NUDIX domain
FICKLOND_01912	0.0	sepA	-	-	Q	-	-	-	COG2015, Alkyl sulfatase and related hydrolases
FICKLOND_01913	4.02e-121	-	-	-	-	-	-	-	-
FICKLOND_01914	1.71e-110	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FICKLOND_01915	1.48e-291	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
FICKLOND_01916	1.16e-158	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
FICKLOND_01917	8.82e-241	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase
FICKLOND_01919	1.69e-107	-	-	-	K	-	-	-	DNA-binding transcription factor activity
FICKLOND_01920	4.2e-264	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Biotin-lipoyl like
FICKLOND_01921	0.0	-	-	-	V	-	-	-	AcrB/AcrD/AcrF family
FICKLOND_01922	8.33e-114	-	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Dihydrofolate reductase
FICKLOND_01923	5.77e-208	-	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Thymidylate synthase
FICKLOND_01924	0.0	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phospholipase D. Active site motifs.
FICKLOND_01925	0.0	-	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	HMGL-like
FICKLOND_01927	0.0	-	-	-	V	ko:K03327	-	ko00000,ko02000	MatE
FICKLOND_01928	1.23e-255	-	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Iron-sulfur cluster assembly protein
FICKLOND_01929	6.78e-42	-	-	-	S	-	-	-	PurA ssDNA and RNA-binding protein
FICKLOND_01931	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	LeuA allosteric (dimerisation) domain
FICKLOND_01932	0.0	prlC	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
FICKLOND_01933	1.58e-282	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FICKLOND_01934	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FICKLOND_01935	0.0	-	-	-	MU	ko:K18139	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Outer membrane efflux protein
FICKLOND_01937	0.0	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
FICKLOND_01938	1.85e-149	-	-	-	-	-	-	-	-
FICKLOND_01941	1.34e-109	ptsN	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
FICKLOND_01942	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
FICKLOND_01943	2.47e-253	-	-	-	L	-	-	-	Transposase IS200 like
FICKLOND_01944	0.0	-	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
FICKLOND_01945	7.89e-268	-	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FICKLOND_01946	1.58e-148	dedA	-	-	S	-	-	-	FtsZ-dependent cytokinesis
FICKLOND_01947	1.3e-116	-	-	-	S	-	-	-	nitrogen fixation
FICKLOND_01948	6.22e-74	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FICKLOND_01949	6.11e-76	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
FICKLOND_01950	1.26e-112	-	-	-	CO	-	-	-	cell redox homeostasis
FICKLOND_01952	1.5e-180	-	-	-	-	-	-	-	-
FICKLOND_01954	0.0	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
FICKLOND_01956	2.33e-143	-	-	-	-	-	-	-	-
FICKLOND_01957	6.96e-64	-	-	-	K	-	-	-	DNA-binding transcription factor activity
FICKLOND_01962	1.24e-200	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
FICKLOND_01963	5.07e-235	-	-	-	S	-	-	-	Peptidase family M28
FICKLOND_01964	0.0	-	-	-	M	-	-	-	Aerotolerance regulator N-terminal
FICKLOND_01965	0.0	-	-	-	S	-	-	-	Large extracellular alpha-helical protein
FICKLOND_01968	1.11e-235	-	-	-	S	ko:K14347	-	ko00000,ko02000,ko04147	SBF-like CPA transporter family (DUF4137)
FICKLOND_01969	2.64e-272	-	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	tRNA synthetases class I (W and Y)
FICKLOND_01970	1.74e-85	-	-	-	S	ko:K09922	-	ko00000	Putative member of DMT superfamily (DUF486)
FICKLOND_01971	4.4e-211	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
FICKLOND_01972	1.6e-217	-	-	-	EP	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
FICKLOND_01973	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
FICKLOND_01974	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
FICKLOND_01975	1.53e-219	-	-	-	O	-	-	-	Thioredoxin-like domain
FICKLOND_01976	4.57e-311	-	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase C-terminal domain
FICKLOND_01977	1.75e-235	-	-	-	S	ko:K01128	-	ko00000,ko01000	acid phosphatase activity
FICKLOND_01981	0.0	-	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Tubulin/FtsZ family, GTPase domain
FICKLOND_01982	3.38e-294	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
FICKLOND_01983	1.72e-147	-	-	-	M	-	-	-	NLP P60 protein
FICKLOND_01984	0.0	-	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
FICKLOND_01985	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
FICKLOND_01986	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
FICKLOND_01987	0.0	-	-	-	H	-	-	-	NAD synthase
FICKLOND_01988	7.86e-174	-	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease MlaE
FICKLOND_01989	4.3e-190	-	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
FICKLOND_01990	1.33e-231	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MlaD protein
FICKLOND_01991	2.69e-38	-	-	-	T	-	-	-	ribosome binding
FICKLOND_01994	5.1e-265	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
FICKLOND_01995	9.11e-261	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
FICKLOND_01996	2.88e-249	ppiD	5.2.1.8	-	O	ko:K03769,ko:K03770,ko:K03771,ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl cis-trans isomerase activity
FICKLOND_01998	0.0	-	-	-	-	-	-	-	-
FICKLOND_01999	2.4e-180	kdsB	2.7.7.38	-	M	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FICKLOND_02000	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
FICKLOND_02001	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
FICKLOND_02002	1.85e-30	-	-	-	-	-	-	-	-
FICKLOND_02003	8.51e-42	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
FICKLOND_02004	0.0	-	-	-	S	-	-	-	Oxygen tolerance
FICKLOND_02005	1.16e-205	yeaE	-	-	S	-	-	-	aldo-keto reductase (NADP) activity
FICKLOND_02006	0.0	-	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Anticodon binding domain
FICKLOND_02007	3.7e-156	-	-	-	S	-	-	-	DUF218 domain
FICKLOND_02008	1.93e-209	-	-	-	S	-	-	-	CAAX protease self-immunity
FICKLOND_02009	1.59e-286	-	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
FICKLOND_02010	8.26e-106	-	-	-	K	-	-	-	Lrp/AsnC ligand binding domain
FICKLOND_02011	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
FICKLOND_02012	8.46e-84	-	-	-	P	ko:K06195	-	ko00000	ApaG domain
FICKLOND_02013	7.47e-203	-	-	-	-	-	-	-	-
FICKLOND_02014	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
FICKLOND_02015	6.07e-192	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
FICKLOND_02016	1.88e-135	-	-	-	K	ko:K07735	-	ko00000,ko03000	Uncharacterized ACR, COG1678
FICKLOND_02017	4.14e-163	-	-	-	S	ko:K06997	-	ko00000	Alanine racemase, N-terminal domain
FICKLOND_02018	0.0	-	-	-	S	-	-	-	50S ribosome-binding GTPase
FICKLOND_02019	1.36e-137	-	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
FICKLOND_02020	8.83e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
FICKLOND_02021	0.0	-	-	-	E	-	-	-	Peptidase dimerisation domain
FICKLOND_02022	3.12e-223	hprK	-	-	T	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
FICKLOND_02023	8.72e-53	-	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
FICKLOND_02024	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FICKLOND_02025	0.0	-	-	-	P	-	-	-	Sulfatase
FICKLOND_02026	1.64e-223	-	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FICKLOND_02027	1.45e-93	-	-	-	S	ko:K02426	-	ko00000	Fe-S metabolism associated domain
FICKLOND_02029	0.0	-	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha amylase, C-terminal all-beta domain
FICKLOND_02030	4.15e-262	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
FICKLOND_02031	0.0	cobD	2.6.1.9, 2.7.7.74, 4.1.1.81	-	M	ko:K00817,ko:K04720,ko:K07281	ko00340,ko00350,ko00360,ko00400,ko00401,ko00562,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00562,map00860,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	nucleotidyl transferase
FICKLOND_02032	1.5e-95	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
FICKLOND_02033	0.0	-	2.7.7.15	-	H	ko:K00968	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
FICKLOND_02034	1.14e-229	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
FICKLOND_02035	1.45e-29	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	PFAM glycosyltransferase sugar-binding region containing DXD motif
FICKLOND_02036	2.88e-63	tagD	2.7.7.39	-	H	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
FICKLOND_02037	2.72e-36	-	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
FICKLOND_02038	1.69e-127	-	-	-	S	-	-	-	protein trimerization
FICKLOND_02040	1.84e-183	-	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
FICKLOND_02041	0.0	-	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP--glucose-1-phosphate uridylyltransferase
FICKLOND_02042	1.67e-123	-	-	-	-	-	-	-	-
FICKLOND_02043	3.09e-61	-	-	-	J	-	-	-	RF-1 domain
FICKLOND_02044	1.79e-122	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FICKLOND_02045	1.28e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
FICKLOND_02046	4.43e-291	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
FICKLOND_02050	1.5e-30	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
FICKLOND_02059	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
FICKLOND_02060	1.06e-182	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
FICKLOND_02061	0.0	-	-	-	KLT	-	-	-	Sulfatase-modifying factor enzyme 1
FICKLOND_02062	3.77e-289	kbl	2.3.1.29	-	E	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
FICKLOND_02063	3.22e-124	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
FICKLOND_02064	1.12e-229	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
FICKLOND_02066	9.9e-121	-	-	-	-	-	-	-	-
FICKLOND_02067	4.13e-184	-	-	-	H	ko:K22132	-	ko00000,ko03016	ThiF family
FICKLOND_02068	1.45e-190	-	-	-	S	ko:K09769	-	ko00000	YmdB-like protein
FICKLOND_02069	1.56e-103	-	-	-	T	-	-	-	Universal stress protein family
FICKLOND_02070	2.41e-232	-	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (W and Y)
FICKLOND_02071	7.55e-206	-	-	-	GM	-	-	-	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FICKLOND_02072	2.05e-163	-	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
FICKLOND_02073	2.55e-94	-	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
FICKLOND_02074	1.28e-223	-	-	-	CO	-	-	-	amine dehydrogenase activity
FICKLOND_02075	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
FICKLOND_02076	2.1e-201	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
FICKLOND_02077	1.93e-63	-	-	-	P	ko:K03972	-	ko00000	Rhodanese Homology Domain
FICKLOND_02078	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-L-fucosidase
FICKLOND_02079	0.0	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
FICKLOND_02080	2.26e-243	-	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	ATP:guanido phosphotransferase, C-terminal catalytic domain
FICKLOND_02081	5.46e-126	-	-	-	S	ko:K19411	-	ko00000	UvrB/uvrC motif
FICKLOND_02082	6.95e-183	-	-	-	P	ko:K09819	-	ko00000,ko00002,ko02000	FecCD transport family
FICKLOND_02083	2.15e-192	-	-	-	P	ko:K09820	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
FICKLOND_02084	2.47e-101	-	-	-	-	-	-	-	-
FICKLOND_02085	4.14e-229	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
FICKLOND_02086	0.0	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
FICKLOND_02087	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
FICKLOND_02088	1.9e-21	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FICKLOND_02104	1.05e-19	-	-	-	OU	-	-	-	Belongs to the peptidase S14 family
FICKLOND_02107	2.05e-42	-	-	-	S	-	-	-	Phage terminase large subunit (GpA)
FICKLOND_02109	5e-252	-	2.3.1.1	-	E	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
FICKLOND_02110	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
FICKLOND_02111	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
FICKLOND_02113	2.11e-173	-	6.3.5.11, 6.3.5.9	-	V	ko:K02224,ko:K18554	ko00860,ko01100,ko01120,map00860,map01100,map01120	br01600,ko00000,ko00001,ko01000,ko01504	Chloramphenicol phosphotransferase-like protein
FICKLOND_02114	1.12e-83	-	-	-	K	ko:K07343	-	ko00000	positive regulation of type IV pilus biogenesis
FICKLOND_02115	5.44e-232	-	-	-	CO	-	-	-	Redoxin
FICKLOND_02116	1.73e-123	paiA	-	-	K	-	-	-	acetyltransferase
FICKLOND_02117	1.87e-215	-	-	-	K	-	-	-	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
FICKLOND_02119	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
FICKLOND_02121	0.0	-	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
FICKLOND_02122	0.0	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
FICKLOND_02124	5.88e-277	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
FICKLOND_02125	1.35e-240	-	-	-	O	-	-	-	Trypsin-like peptidase domain
FICKLOND_02126	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Transglycosylase
FICKLOND_02127	5.99e-286	-	-	-	S	ko:K09760	-	ko00000	RmuC family
FICKLOND_02128	1.4e-171	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
FICKLOND_02129	1.25e-132	-	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FICKLOND_02130	3.74e-208	-	-	-	S	-	-	-	RDD family
FICKLOND_02131	0.0	-	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MacB-like periplasmic core domain
FICKLOND_02132	2.45e-205	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
FICKLOND_02133	2.27e-90	-	-	-	S	ko:K09793	-	ko00000	Protein of unknown function (DUF456)
FICKLOND_02134	5.62e-57	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
FICKLOND_02135	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
FICKLOND_02136	9.38e-260	-	-	-	S	-	-	-	Peptidase family M28
FICKLOND_02137	1e-248	-	-	-	I	-	-	-	alpha/beta hydrolase fold
FICKLOND_02138	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FICKLOND_02139	1.76e-186	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase (SPase) II
FICKLOND_02140	1.19e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
FICKLOND_02141	3.13e-114	-	-	-	P	-	-	-	Rhodanese-like domain
FICKLOND_02142	1.34e-298	-	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FICKLOND_02143	0.0	-	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FICKLOND_02144	0.000232	-	2.7.11.1, 2.7.11.17	-	T	ko:K08794,ko:K13412,ko:K17530	ko04626,ko04921,ko04925,ko05145,map04626,map04921,map04925,map05145	ko00000,ko00001,ko01000,ko01001	protein serine/threonine kinase activity
FICKLOND_02146	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
FICKLOND_02147	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
FICKLOND_02148	4.12e-100	-	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Glyoxalase-like domain
FICKLOND_02149	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
FICKLOND_02151	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FICKLOND_02152	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA Topoisomerase IV
FICKLOND_02153	2.66e-147	-	-	-	C	-	-	-	lactate oxidation
FICKLOND_02154	1.02e-296	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32
FICKLOND_02155	1e-20	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	COG0010 Arginase agmatinase formimionoglutamate hydrolase arginase family
FICKLOND_02156	0.0	-	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
FICKLOND_02157	0.0	-	-	-	C	-	-	-	cytochrome C peroxidase
FICKLOND_02158	6.9e-282	-	-	-	J	-	-	-	PFAM Endoribonuclease L-PSP
FICKLOND_02160	1.33e-151	phoU	-	-	P	ko:K02039	-	ko00000	negative regulation of phosphate transmembrane transport
FICKLOND_02161	8.04e-184	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FICKLOND_02162	0.0	-	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
FICKLOND_02163	0.0	pstC	-	-	P	ko:K02037,ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
FICKLOND_02164	1.51e-221	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	PBP superfamily domain
FICKLOND_02165	5.24e-185	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FICKLOND_02166	1.75e-139	-	-	-	P	ko:K02039	-	ko00000	PhoU domain
FICKLOND_02167	6.15e-234	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
FICKLOND_02168	7.65e-101	-	-	-	M	ko:K06077	-	ko00000	Glycine zipper 2TM domain
FICKLOND_02170	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
FICKLOND_02171	4.72e-153	-	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
FICKLOND_02172	2.13e-230	-	-	-	L	-	-	-	Elongator protein 3, MiaB family, Radical SAM
FICKLOND_02173	3.03e-231	-	-	-	J	-	-	-	Belongs to the universal ribosomal protein uS2 family
FICKLOND_02174	2.51e-103	-	-	-	K	-	-	-	DNA-binding transcription factor activity
FICKLOND_02176	2.48e-315	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FICKLOND_02177	8.1e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FICKLOND_02178	0.0	-	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Mur ligase middle domain
FICKLOND_02179	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FICKLOND_02180	0.0	-	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein dimerisation domain
FICKLOND_02182	0.0	rsmH	2.1.1.199	-	M	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
FICKLOND_02183	4.54e-105	-	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
FICKLOND_02184	5.27e-189	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
FICKLOND_02185	2.82e-154	-	-	-	S	-	-	-	UPF0126 domain
FICKLOND_02186	3.95e-13	-	-	-	S	-	-	-	Mac 1
FICKLOND_02187	6.74e-138	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
FICKLOND_02188	7.91e-305	mnmE	-	-	J	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FICKLOND_02189	2.72e-263	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
FICKLOND_02190	1.24e-195	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FICKLOND_02191	2.94e-184	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
FICKLOND_02192	4.96e-271	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
FICKLOND_02193	1.77e-142	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
FICKLOND_02194	6.03e-270	-	-	-	M	-	-	-	Glycosyl transferases group 1
FICKLOND_02195	2.21e-264	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
FICKLOND_02196	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
FICKLOND_02197	1.71e-18	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
FICKLOND_02199	2.93e-39	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
FICKLOND_02200	1.07e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
FICKLOND_02201	5.19e-178	-	-	-	S	-	-	-	Lysin motif
FICKLOND_02202	3.5e-132	-	-	-	-	-	-	-	-
FICKLOND_02203	8.56e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
FICKLOND_02204	7.16e-174	coaX	2.7.1.33	-	K	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Type III pantothenate kinase
FICKLOND_02205	6.81e-273	-	-	-	M	-	-	-	Monogalactosyldiacylglycerol (MGDG) synthase
FICKLOND_02206	3.02e-227	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FICKLOND_02207	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
FICKLOND_02209	0.0	-	-	-	S	ko:K03307	-	ko00000	Sodium:solute symporter family
FICKLOND_02210	8.88e-284	-	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Galactokinase galactose-binding signature
FICKLOND_02211	0.0	-	-	-	M	-	-	-	Bacterial sugar transferase
FICKLOND_02212	7.33e-143	-	-	-	S	-	-	-	RNA recognition motif
FICKLOND_02213	1.02e-184	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
FICKLOND_02214	0.0	-	-	-	-	-	-	-	-
FICKLOND_02216	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
FICKLOND_02217	0.0	-	-	-	C	-	-	-	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein
FICKLOND_02218	2.83e-204	-	-	-	S	-	-	-	Domain of unknown function (DUF362)
FICKLOND_02219	2.47e-134	-	-	-	J	-	-	-	Putative rRNA methylase
FICKLOND_02220	1.72e-144	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FICKLOND_02221	3.73e-195	-	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
FICKLOND_02222	5.58e-289	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	NusA-like KH domain
FICKLOND_02223	4.25e-160	-	-	-	S	-	-	-	Terminase
FICKLOND_02225	5.03e-28	-	-	-	-	-	-	-	-
FICKLOND_02231	1.79e-304	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
FICKLOND_02243	1.04e-65	-	-	-	KT	-	-	-	Peptidase S24-like
FICKLOND_02245	3.26e-64	-	-	-	F	-	-	-	acetyltransferase
FICKLOND_02246	5.44e-147	-	-	-	IQ	-	-	-	RmlD substrate binding domain
FICKLOND_02247	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GcpE protein
FICKLOND_02248	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
FICKLOND_02249	1.51e-198	-	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FICKLOND_02250	4.03e-120	-	-	-	-	-	-	-	-
FICKLOND_02251	3.85e-194	-	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	CDP-alcohol phosphatidyltransferase
FICKLOND_02252	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FICKLOND_02253	1.37e-227	-	-	-	M	ko:K01993	-	ko00000	HlyD family secretion protein
FICKLOND_02254	0.0	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
FICKLOND_02255	1.03e-243	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
FICKLOND_02256	7.57e-247	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
FICKLOND_02266	4.71e-33	-	-	-	M	-	-	-	lytic transglycosylase activity
FICKLOND_02272	3.4e-178	-	-	-	O	-	-	-	Trypsin
FICKLOND_02273	3.31e-239	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
FICKLOND_02274	6.2e-203	-	-	-	-	-	-	-	-
FICKLOND_02275	0.0	-	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
FICKLOND_02276	2.74e-284	-	-	-	S	-	-	-	Tetratricopeptide repeat
FICKLOND_02279	2.63e-10	-	-	-	-	-	-	-	-
FICKLOND_02281	8.23e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FICKLOND_02282	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
FICKLOND_02283	2.48e-228	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
FICKLOND_02284	1.26e-210	-	-	-	S	-	-	-	Protein of unknown function DUF58
FICKLOND_02285	8.06e-134	-	-	-	-	-	-	-	-
FICKLOND_02286	2.3e-229	-	-	-	S	-	-	-	Protein of unknown function (DUF1194)
FICKLOND_02289	6.21e-39	-	-	-	-	-	-	-	-
FICKLOND_02290	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
FICKLOND_02292	9.83e-235	-	-	-	CO	-	-	-	Thioredoxin-like
FICKLOND_02293	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
FICKLOND_02294	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
FICKLOND_02295	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
FICKLOND_02296	1.6e-75	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
FICKLOND_02297	3.32e-210	ybfH	-	-	EG	-	-	-	spore germination
FICKLOND_02298	6.7e-132	-	-	-	-	-	-	-	-
FICKLOND_02299	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
FICKLOND_02300	1.47e-120	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FICKLOND_02301	7.48e-188	-	-	-	O	ko:K04083	-	ko00000,ko03110	Hsp33 protein
FICKLOND_02304	2.93e-233	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
FICKLOND_02307	7.93e-104	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FICKLOND_02308	6.42e-101	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
FICKLOND_02310	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
FICKLOND_02311	6.41e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
FICKLOND_02312	7.48e-192	map	3.4.11.18	-	J	ko:K01265	-	ko00000,ko01000,ko01002	Metallopeptidase family M24
FICKLOND_02313	8.13e-264	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
FICKLOND_02314	0.0	-	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
FICKLOND_02315	0.0	-	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Polyphosphate kinase middle domain
FICKLOND_02316	1.24e-282	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
FICKLOND_02318	8.96e-274	-	-	GT2	S	ko:K19427	-	ko00000,ko01000	PFAM glycosyl transferase family 2
FICKLOND_02319	3.06e-226	-	-	-	S	-	-	-	Glycosyl transferase family 11
FICKLOND_02320	4.88e-263	-	-	-	S	-	-	-	Glycosyltransferase like family 2
FICKLOND_02321	3.37e-292	-	-	-	-	-	-	-	-
FICKLOND_02322	6.2e-265	-	-	-	S	-	-	-	PFAM glycosyl transferase family 2
FICKLOND_02323	3.93e-128	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
FICKLOND_02324	1.82e-138	-	-	-	C	-	-	-	e3 binding domain
FICKLOND_02325	1.03e-298	nupG	-	-	G	ko:K03289,ko:K03301,ko:K08218,ko:K11537	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
FICKLOND_02326	4.16e-259	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FICKLOND_02327	1.98e-109	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07305,ko:K12267	-	ko00000,ko01000	peptide-methionine (R)-S-oxide reductase activity
FICKLOND_02328	3.9e-306	-	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
FICKLOND_02330	5.12e-145	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FICKLOND_02331	2.37e-46	-	-	-	J	-	-	-	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FICKLOND_02332	0.0	-	-	-	-	-	-	-	-
FICKLOND_02333	0.0	-	-	-	S	-	-	-	Sodium:neurotransmitter symporter family
FICKLOND_02334	3.6e-152	-	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
FICKLOND_02335	1.45e-208	-	-	-	M	-	-	-	Mechanosensitive ion channel
FICKLOND_02336	4.62e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Amino acid kinase family
FICKLOND_02337	2.53e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
FICKLOND_02338	9.17e-70	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
FICKLOND_02350	8.71e-301	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
FICKLOND_02351	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
FICKLOND_02353	3.29e-146	-	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FICKLOND_02354	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FICKLOND_02356	4.89e-237	-	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
FICKLOND_02358	2.04e-160	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
FICKLOND_02359	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
FICKLOND_02360	1.72e-230	-	4.1.1.35	-	M	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	3-beta hydroxysteroid dehydrogenase/isomerase family
FICKLOND_02361	2.15e-183	-	-	-	I	-	-	-	Acyl-ACP thioesterase
FICKLOND_02362	6.37e-24	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
FICKLOND_02366	3.77e-138	nuoB	1.6.5.3	-	C	ko:K00331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FICKLOND_02367	3.49e-139	nuoC	1.6.5.3	-	C	ko:K00332	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FICKLOND_02368	1.55e-164	-	-	-	-	-	-	-	-
FICKLOND_02369	1.27e-70	-	-	-	K	-	-	-	ribonuclease III activity
FICKLOND_02370	6.58e-276	-	6.2.1.26	-	IQ	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	AMP-binding enzyme
FICKLOND_02372	0.0	-	-	-	S	ko:K07126,ko:K13582	ko04112,map04112	ko00000,ko00001	beta-lactamase activity
FICKLOND_02373	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
FICKLOND_02374	1.69e-06	-	-	-	-	-	-	-	-
FICKLOND_02375	4.34e-284	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FICKLOND_02376	4.05e-135	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FICKLOND_02377	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
FICKLOND_02378	0.0	-	-	-	T	-	-	-	5TM C-terminal transporter carbon starvation CstA
FICKLOND_02379	9.44e-159	-	-	-	-	-	-	-	-
FICKLOND_02380	0.0	-	-	-	P	-	-	-	PA14 domain
FICKLOND_02381	3.87e-80	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FICKLOND_02382	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FICKLOND_02396	1.1e-76	-	-	-	M	-	-	-	self proteolysis
FICKLOND_02399	1.25e-87	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
FICKLOND_02415	2.4e-189	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family