Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HLFCFMOD_00002	1.25e-204	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HLFCFMOD_00003	4.14e-175	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate reductase, N-terminus
HLFCFMOD_00004	4.21e-121	-	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HLFCFMOD_00005	4.13e-183	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HLFCFMOD_00006	1.96e-226	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HLFCFMOD_00007	7.29e-211	-	-	-	M	-	-	-	Peptidase family M23
HLFCFMOD_00012	1.44e-109	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HLFCFMOD_00013	3.48e-134	-	-	-	C	-	-	-	Nitroreductase family
HLFCFMOD_00015	0.0	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
HLFCFMOD_00016	1.66e-87	-	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HLFCFMOD_00017	1.03e-237	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HLFCFMOD_00018	8.07e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	tRNA (Guanine-1)-methyltransferase
HLFCFMOD_00019	2.05e-28	-	-	-	-	-	-	-	-
HLFCFMOD_00021	2.37e-237	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
HLFCFMOD_00022	1.21e-55	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HLFCFMOD_00023	0.0	-	-	-	J	ko:K07576	-	ko00000	Beta-Casp domain
HLFCFMOD_00024	1.55e-83	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	ArsC family
HLFCFMOD_00025	8.34e-180	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
HLFCFMOD_00026	0.0	-	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Carbohydrate phosphorylase
HLFCFMOD_00027	2.04e-258	tdh	1.1.1.103	-	E	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HLFCFMOD_00028	5.46e-161	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLFCFMOD_00030	1.23e-179	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HLFCFMOD_00031	3.92e-115	-	-	-	-	-	-	-	-
HLFCFMOD_00034	0.0	-	-	-	L	-	-	-	DNA restriction-modification system
HLFCFMOD_00037	2.55e-171	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
HLFCFMOD_00039	1.49e-178	-	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HLFCFMOD_00041	9.04e-317	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
HLFCFMOD_00042	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HLFCFMOD_00043	2.76e-267	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HLFCFMOD_00044	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HLFCFMOD_00046	0.0	-	-	-	G	-	-	-	alpha-galactosidase
HLFCFMOD_00047	0.000553	-	-	-	-	-	-	-	-
HLFCFMOD_00048	0.0	poxB	1.2.3.3, 1.2.5.1	-	EH	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
HLFCFMOD_00049	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLFCFMOD_00050	2.72e-183	-	-	-	L	ko:K10800	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	uracil-dna glycosylase
HLFCFMOD_00051	1.13e-228	-	2.7.1.11	-	G	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Phosphofructokinase
HLFCFMOD_00052	8.83e-270	-	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
HLFCFMOD_00053	9.53e-206	-	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HLFCFMOD_00055	0.0	-	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
HLFCFMOD_00056	1.35e-191	-	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HLFCFMOD_00057	0.0	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
HLFCFMOD_00058	3.41e-55	-	-	-	I	-	-	-	PFAM biotin lipoyl attachment domain-containing protein
HLFCFMOD_00060	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
HLFCFMOD_00061	4.12e-100	-	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Glyoxalase-like domain
HLFCFMOD_00062	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HLFCFMOD_00063	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HLFCFMOD_00065	0.000231	-	2.7.11.1, 2.7.11.17	-	T	ko:K08794,ko:K13412,ko:K17530	ko04626,ko04921,ko04925,ko05145,map04626,map04921,map04925,map05145	ko00000,ko00001,ko01000,ko01001	protein serine/threonine kinase activity
HLFCFMOD_00066	0.0	-	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HLFCFMOD_00067	1.56e-297	-	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HLFCFMOD_00068	3.13e-114	-	-	-	P	-	-	-	Rhodanese-like domain
HLFCFMOD_00069	1.19e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HLFCFMOD_00070	1.76e-186	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase (SPase) II
HLFCFMOD_00071	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HLFCFMOD_00072	1.17e-247	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HLFCFMOD_00073	1.46e-09	-	-	-	S	-	-	-	Peptidase family M28
HLFCFMOD_00074	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HLFCFMOD_00075	4.81e-58	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HLFCFMOD_00076	2.64e-89	-	-	-	S	ko:K09793	-	ko00000	Protein of unknown function (DUF456)
HLFCFMOD_00077	3.39e-210	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HLFCFMOD_00078	0.0	-	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MacB-like periplasmic core domain
HLFCFMOD_00079	5.32e-208	-	-	-	S	-	-	-	RDD family
HLFCFMOD_00080	1.25e-132	-	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HLFCFMOD_00081	6.64e-170	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HLFCFMOD_00082	5.99e-286	-	-	-	S	ko:K09760	-	ko00000	RmuC family
HLFCFMOD_00083	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Transglycosylase
HLFCFMOD_00084	1.35e-240	-	-	-	O	-	-	-	Trypsin-like peptidase domain
HLFCFMOD_00085	5.88e-277	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HLFCFMOD_00087	0.0	-	-	-	-	-	-	-	-
HLFCFMOD_00088	1.67e-313	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
HLFCFMOD_00089	5.55e-143	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
HLFCFMOD_00090	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate--tetrahydrofolate ligase
HLFCFMOD_00091	1.65e-221	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase PanE/ApbA C terminal
HLFCFMOD_00092	1.65e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
HLFCFMOD_00093	8.08e-185	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HLFCFMOD_00094	0.0	-	-	-	EP	ko:K13894	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLFCFMOD_00095	0.0	-	-	-	P	ko:K13895	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLFCFMOD_00096	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HLFCFMOD_00097	1.82e-229	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HLFCFMOD_00098	6.48e-244	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HLFCFMOD_00099	1.48e-272	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLFCFMOD_00101	6.56e-110	-	-	-	L	-	-	-	endonuclease activity
HLFCFMOD_00102	3.07e-208	-	-	-	EG	-	-	-	EamA-like transporter family
HLFCFMOD_00103	2.4e-285	-	-	-	Q	-	-	-	Multicopper oxidase
HLFCFMOD_00104	0.0	-	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
HLFCFMOD_00105	2.77e-186	-	-	-	O	-	-	-	Parallel beta-helix repeats
HLFCFMOD_00107	2.37e-222	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HLFCFMOD_00109	1.3e-139	-	-	-	K	-	-	-	ECF sigma factor
HLFCFMOD_00110	6.54e-222	ytpP	2.7.1.180, 5.3.4.1	-	CO	ko:K01829,ko:K03671,ko:K03734,ko:K06196	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko02000,ko03110	cell redox homeostasis
HLFCFMOD_00111	0.0	-	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	ThiC-associated domain
HLFCFMOD_00112	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HLFCFMOD_00113	7.29e-60	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
HLFCFMOD_00114	2.34e-134	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
HLFCFMOD_00115	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	N-terminal domain of BNR-repeat neuraminidase
HLFCFMOD_00116	2.34e-123	-	-	-	-	-	-	-	-
HLFCFMOD_00117	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HLFCFMOD_00118	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
HLFCFMOD_00120	0.0	-	2.7.1.51	-	G	ko:K00879	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HLFCFMOD_00121	8.82e-203	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
HLFCFMOD_00123	0.0	-	-	-	M	-	-	-	AsmA-like C-terminal region
HLFCFMOD_00124	7.48e-171	-	-	-	S	ko:K06911	-	ko00000	Pirin
HLFCFMOD_00126	2.05e-173	-	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	FtsJ-like methyltransferase
HLFCFMOD_00129	3.9e-213	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLFCFMOD_00130	6.71e-285	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HLFCFMOD_00131	4.7e-57	-	-	-	S	ko:K06960	-	ko00000	KH domain
HLFCFMOD_00132	0.0	-	-	-	-	-	-	-	-
HLFCFMOD_00133	0.0	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	RNA cap guanine-N2 methyltransferase
HLFCFMOD_00134	2.15e-216	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HLFCFMOD_00135	5.51e-240	-	4.2.1.113	-	M	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Mandelate Racemase Muconate Lactonizing
HLFCFMOD_00136	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HLFCFMOD_00137	1.09e-121	-	-	-	D	-	-	-	MobA MobL family protein
HLFCFMOD_00138	2.25e-49	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLFCFMOD_00140	0.0	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
HLFCFMOD_00141	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HLFCFMOD_00142	4.73e-102	-	-	-	G	-	-	-	single-species biofilm formation
HLFCFMOD_00143	2.29e-112	-	-	-	K	ko:K13640	-	ko00000,ko03000	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HLFCFMOD_00144	4.8e-128	-	-	-	S	-	-	-	Flavodoxin-like fold
HLFCFMOD_00145	6.4e-188	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
HLFCFMOD_00146	2.82e-100	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HLFCFMOD_00147	1.17e-127	-	-	-	C	-	-	-	FMN binding
HLFCFMOD_00148	3.6e-265	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HLFCFMOD_00149	5.16e-271	-	-	-	C	-	-	-	Aldo/keto reductase family
HLFCFMOD_00150	2.97e-268	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HLFCFMOD_00151	9.86e-49	-	-	-	S	-	-	-	Aldo/keto reductase family
HLFCFMOD_00152	1.03e-195	-	-	-	-	-	-	-	-
HLFCFMOD_00153	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HLFCFMOD_00154	1.56e-137	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
HLFCFMOD_00156	5.06e-182	-	-	-	Q	-	-	-	methyltransferase activity
HLFCFMOD_00157	0.0	-	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	NAD synthase
HLFCFMOD_00158	2.28e-79	-	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HLFCFMOD_00160	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	exo-alpha-(2->6)-sialidase activity
HLFCFMOD_00161	7.72e-279	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
HLFCFMOD_00162	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR/Asp-box repeat
HLFCFMOD_00163	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HLFCFMOD_00165	1.59e-37	-	-	-	KLT	-	-	-	Protein kinase domain
HLFCFMOD_00168	1.57e-08	-	-	-	S	ko:K06867	-	ko00000	Ankyrin repeat protein
HLFCFMOD_00173	1.57e-53	draG	3.2.2.24	-	O	ko:K05521	-	ko00000,ko01000	ADP-ribosylglycohydrolase
HLFCFMOD_00174	6.01e-46	-	-	-	L	-	-	-	AAA ATPase domain
HLFCFMOD_00177	4.39e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HLFCFMOD_00178	9.5e-239	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLFCFMOD_00179	4.5e-283	-	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HLFCFMOD_00180	1.1e-256	MA20_42350	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyl transferase, family 2
HLFCFMOD_00182	9.28e-249	-	-	-	M	-	-	-	Glycosyl transferase, family 2
HLFCFMOD_00183	8.4e-39	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HLFCFMOD_00184	2.11e-154	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HLFCFMOD_00186	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
HLFCFMOD_00187	3.32e-288	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HLFCFMOD_00188	5.71e-284	-	-	-	M	-	-	-	Glycosyl transferases group 1
HLFCFMOD_00189	4.35e-143	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HLFCFMOD_00190	4.96e-271	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HLFCFMOD_00191	6.92e-183	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HLFCFMOD_00192	9.9e-202	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HLFCFMOD_00193	1.11e-262	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HLFCFMOD_00194	2.41e-315	mnmE	-	-	J	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HLFCFMOD_00195	1.67e-08	-	-	-	S	-	-	-	Mac 1
HLFCFMOD_00196	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HLFCFMOD_00197	1.89e-35	-	-	-	-	-	-	-	-
HLFCFMOD_00198	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
HLFCFMOD_00199	6.57e-313	-	-	-	D	-	-	-	MobA MobL family protein
HLFCFMOD_00200	4.5e-61	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HLFCFMOD_00201	1.63e-43	-	-	-	-	-	-	-	-
HLFCFMOD_00202	2.77e-45	-	-	-	K	-	-	-	Helix-turn-helix domain
HLFCFMOD_00203	1.87e-270	-	-	-	-	-	-	-	-
HLFCFMOD_00204	3.28e-63	-	-	-	O	-	-	-	Torsin
HLFCFMOD_00206	8.58e-45	-	-	-	-	-	-	-	-
HLFCFMOD_00207	4.42e-235	-	-	-	V	-	-	-	HNH endonuclease
HLFCFMOD_00208	0.0	-	-	-	L	-	-	-	C-5 cytosine-specific DNA methylase
HLFCFMOD_00211	2.82e-154	-	-	-	S	-	-	-	UPF0126 domain
HLFCFMOD_00212	5.27e-189	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HLFCFMOD_00213	4.54e-105	-	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HLFCFMOD_00214	0.0	rsmH	2.1.1.199	-	M	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HLFCFMOD_00216	0.0	-	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein dimerisation domain
HLFCFMOD_00217	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLFCFMOD_00218	0.0	-	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Mur ligase middle domain
HLFCFMOD_00219	1.99e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLFCFMOD_00220	1.79e-312	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HLFCFMOD_00221	6.01e-61	nuoK	1.6.5.3	-	C	ko:K00340	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HLFCFMOD_00222	0.0	-	1.6.5.3	-	CP	ko:K00341	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
HLFCFMOD_00223	0.0	-	1.6.5.3	-	C	ko:K00342	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Proton-conducting membrane transporter
HLFCFMOD_00224	0.0	nuoN	1.6.5.3	-	C	ko:K00343	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HLFCFMOD_00225	3.12e-219	-	-	-	E	-	-	-	Domain of unknown function (DUF3472)
HLFCFMOD_00227	2.59e-107	-	-	-	-	-	-	-	-
HLFCFMOD_00228	9.74e-126	-	-	-	S	-	-	-	Pfam:DUF59
HLFCFMOD_00229	0.0	-	5.2.1.8	-	O	ko:K03770	-	ko00000,ko01000,ko03110	PPIC-type PPIASE domain
HLFCFMOD_00230	0.0	-	-	-	E	ko:K03305	-	ko00000	POT family
HLFCFMOD_00231	1.07e-238	-	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Polyprenyl synthetase
HLFCFMOD_00232	3.23e-289	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HLFCFMOD_00233	1.97e-190	-	-	-	L	ko:K06864	-	ko00000	tRNA processing
HLFCFMOD_00234	1.47e-171	-	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HLFCFMOD_00235	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase-like 10
HLFCFMOD_00236	1.74e-157	-	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Iron/manganese superoxide dismutases, alpha-hairpin domain
HLFCFMOD_00237	1.26e-271	-	-	-	IM	-	-	-	Cytidylyltransferase-like
HLFCFMOD_00238	0.0	murJ	-	-	S	ko:K03980	-	ko00000,ko01011,ko02000	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HLFCFMOD_00239	1.1e-280	-	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HLFCFMOD_00240	2.83e-110	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
HLFCFMOD_00241	5.14e-245	-	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLFCFMOD_00242	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HLFCFMOD_00243	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein E, N-terminal domain
HLFCFMOD_00244	4.02e-282	-	-	-	NU	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
HLFCFMOD_00246	3.38e-224	-	-	-	M	-	-	-	Glycosyl transferase family 2
HLFCFMOD_00247	8.2e-209	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HLFCFMOD_00248	1.3e-104	-	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	NDK
HLFCFMOD_00249	3.37e-109	-	-	-	-	-	-	-	-
HLFCFMOD_00250	3.51e-136	-	5.4.99.20	-	J	ko:K06181	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HLFCFMOD_00251	1.5e-44	-	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	RNA polymerase activity
HLFCFMOD_00252	6.68e-103	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HLFCFMOD_00253	4.12e-139	-	-	-	L	-	-	-	RNase_H superfamily
HLFCFMOD_00254	3.86e-112	-	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HLFCFMOD_00256	4.28e-274	-	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
HLFCFMOD_00257	1.39e-152	-	-	-	O	-	-	-	Glycoprotease family
HLFCFMOD_00258	1.79e-213	-	-	-	-	-	-	-	-
HLFCFMOD_00261	2.89e-123	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HLFCFMOD_00263	7.9e-289	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
HLFCFMOD_00264	0.0	-	-	-	S	-	-	-	Alpha-2-macroglobulin family
HLFCFMOD_00265	3.57e-190	dpnC	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Dam-replacing family
HLFCFMOD_00266	3.07e-211	MA20_36650	-	-	EG	-	-	-	spore germination
HLFCFMOD_00267	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HLFCFMOD_00268	0.0	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
HLFCFMOD_00271	0.0	-	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Peptidase family M50
HLFCFMOD_00272	5.25e-79	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HLFCFMOD_00273	2.91e-38	-	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
HLFCFMOD_00275	5.46e-189	-	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
HLFCFMOD_00277	0.0	-	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	DHHA2
HLFCFMOD_00278	1.89e-253	-	-	-	N	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease Exonuclease Phosphatase
HLFCFMOD_00279	8.25e-63	-	-	-	L	ko:K09747	-	ko00000	YbaB/EbfC DNA-binding family
HLFCFMOD_00280	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLFCFMOD_00282	4.03e-174	-	-	-	D	-	-	-	Phage-related minor tail protein
HLFCFMOD_00284	1.69e-174	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
HLFCFMOD_00285	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HLFCFMOD_00286	6.12e-40	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HLFCFMOD_00287	2.79e-97	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HLFCFMOD_00288	1.67e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S9/S16
HLFCFMOD_00289	1.27e-99	-	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Predicted SPOUT methyltransferase
HLFCFMOD_00290	0.0	-	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HLFCFMOD_00291	8.63e-181	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HLFCFMOD_00292	1.26e-96	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
HLFCFMOD_00293	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HLFCFMOD_00294	0.0	-	-	-	M	-	-	-	PFAM glycosyl transferase family 51
HLFCFMOD_00295	8.31e-186	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HLFCFMOD_00296	5.31e-115	ispF	4.6.1.12	-	I	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HLFCFMOD_00297	1.29e-181	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HLFCFMOD_00298	4.84e-229	-	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphomannose isomerase type I
HLFCFMOD_00299	1.11e-236	-	-	-	-	-	-	-	-
HLFCFMOD_00300	1.45e-296	-	-	-	C	-	-	-	Na+/H+ antiporter family
HLFCFMOD_00301	1.03e-265	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
HLFCFMOD_00302	6.96e-265	-	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HLFCFMOD_00303	1.09e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase small chain, CPSase domain
HLFCFMOD_00304	0.0	-	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HLFCFMOD_00305	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HLFCFMOD_00306	0.0	-	1.4.1.13, 1.4.1.14	-	E	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
HLFCFMOD_00307	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
HLFCFMOD_00308	4.61e-61	-	-	-	S	ko:K08998	-	ko00000	Haemolytic
HLFCFMOD_00309	4.9e-76	-	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	Ribonuclease P
HLFCFMOD_00310	1.1e-34	-	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
HLFCFMOD_00311	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HLFCFMOD_00312	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HLFCFMOD_00313	0.0	-	-	-	G	-	-	-	Trehalase
HLFCFMOD_00314	1.42e-210	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HLFCFMOD_00315	3.45e-157	-	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
HLFCFMOD_00316	1.19e-199	-	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
HLFCFMOD_00317	2.63e-208	-	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Polyprenyl synthetase
HLFCFMOD_00318	4.49e-241	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HLFCFMOD_00320	5.5e-176	-	-	-	-	-	-	-	-
HLFCFMOD_00321	0.0	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
HLFCFMOD_00322	1.02e-220	-	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HLFCFMOD_00323	3.47e-180	-	-	-	E	ko:K00612	-	ko00000,ko01000	lipolytic protein G-D-S-L family
HLFCFMOD_00324	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HLFCFMOD_00325	0.0	rarA	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
HLFCFMOD_00326	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
HLFCFMOD_00328	9.1e-300	-	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HLFCFMOD_00329	1.49e-215	-	-	-	M	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HLFCFMOD_00330	2.18e-269	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
HLFCFMOD_00333	4.46e-127	cobU	2.7.1.156, 2.7.7.62, 6.3.5.10	-	H	ko:K02231,ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cobinamide kinase activity
HLFCFMOD_00334	2.17e-203	-	-	-	G	-	-	-	myo-inosose-2 dehydratase activity
HLFCFMOD_00335	6.86e-174	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HLFCFMOD_00336	2.08e-241	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HLFCFMOD_00337	1.11e-237	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HLFCFMOD_00338	0.0	cobQ	-	-	H	-	-	-	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HLFCFMOD_00339	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
HLFCFMOD_00341	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HLFCFMOD_00342	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HLFCFMOD_00343	6.65e-160	-	-	-	M	ko:K16079	-	ko00000,ko02000	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HLFCFMOD_00344	1.4e-314	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HLFCFMOD_00345	0.0	-	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HLFCFMOD_00346	5.53e-96	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
HLFCFMOD_00347	1.1e-57	-	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	nucleotidyltransferase activity
HLFCFMOD_00348	3.09e-231	-	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HLFCFMOD_00349	0.0	-	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoglutarate dehydrogenase C-terminal
HLFCFMOD_00350	1.48e-245	-	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit II
HLFCFMOD_00351	0.0	-	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
HLFCFMOD_00352	2.7e-113	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HLFCFMOD_00353	2.34e-107	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HLFCFMOD_00354	0.0	-	-	-	T	-	-	-	Chase2 domain
HLFCFMOD_00355	1.51e-235	-	2.7.1.221	-	S	ko:K07102	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Phosphotransferase enzyme family
HLFCFMOD_00356	1.25e-307	-	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HLFCFMOD_00357	4.98e-92	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HLFCFMOD_00359	1e-112	-	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Ferritin-like domain
HLFCFMOD_00360	0.0	-	-	-	-	-	-	-	-
HLFCFMOD_00361	3.15e-103	-	-	-	J	-	-	-	YjgF/chorismate_mutase-like, putative endoribonuclease
HLFCFMOD_00363	6.29e-115	-	-	-	S	ko:K03748	-	ko00000	DUF218 domain
HLFCFMOD_00365	1.97e-230	-	-	-	S	-	-	-	mannose-ethanolamine phosphotransferase activity
HLFCFMOD_00371	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RQC
HLFCFMOD_00373	2.23e-176	-	-	-	-	-	-	-	-
HLFCFMOD_00374	3.89e-209	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HLFCFMOD_00376	2.1e-296	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HLFCFMOD_00378	1.63e-239	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HLFCFMOD_00380	5.75e-202	-	-	-	O	-	-	-	stress-induced mitochondrial fusion
HLFCFMOD_00381	3.62e-204	-	-	-	S	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
HLFCFMOD_00382	1.03e-121	-	-	-	M	ko:K03098	-	ko00000,ko04147	Lipocalin-like domain
HLFCFMOD_00383	1.35e-236	-	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HLFCFMOD_00384	3.41e-188	-	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HLFCFMOD_00385	1.6e-151	-	-	-	K	-	-	-	Transcriptional regulator
HLFCFMOD_00386	1.35e-264	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HLFCFMOD_00388	0.0	-	-	-	P	-	-	-	Sulfatase
HLFCFMOD_00389	1.26e-79	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
HLFCFMOD_00390	4.6e-305	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLFCFMOD_00391	0.0	-	-	-	E	-	-	-	Aminotransferase class I and II
HLFCFMOD_00392	3.56e-219	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HLFCFMOD_00393	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha galactosidase A
HLFCFMOD_00394	1.04e-49	-	-	-	-	-	-	-	-
HLFCFMOD_00395	1.45e-55	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HLFCFMOD_00396	4.69e-236	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HLFCFMOD_00397	2.13e-96	-	-	-	L	ko:K07447	-	ko00000,ko01000	Likely ribonuclease with RNase H fold.
HLFCFMOD_00398	9.8e-259	-	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HLFCFMOD_00399	2.06e-171	-	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HLFCFMOD_00400	0.0	-	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	TopoisomeraseII
HLFCFMOD_00401	8.53e-211	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HLFCFMOD_00403	0.0	-	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	HELICc2
HLFCFMOD_00404	2.79e-178	cbiO	-	-	P	ko:K02006,ko:K02008,ko:K16784,ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase activity
HLFCFMOD_00405	2.32e-193	cbiQ	-	-	P	ko:K02007,ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transmembrane transporter activity
HLFCFMOD_00406	8.77e-239	cbiM	-	-	P	ko:K02007,ko:K02009,ko:K16915	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt ion transport
HLFCFMOD_00408	8.06e-18	-	-	-	S	-	-	-	Lipocalin-like
HLFCFMOD_00409	3.2e-209	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HLFCFMOD_00410	1.05e-226	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HLFCFMOD_00411	1.06e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L9, N-terminal domain
HLFCFMOD_00412	0.0	-	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT/IMPCHase bienzyme
HLFCFMOD_00413	1.33e-171	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HLFCFMOD_00414	9.05e-85	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	4'-phosphopantetheinyl transferase superfamily
HLFCFMOD_00416	0.0	pckG	4.1.1.32	-	C	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
HLFCFMOD_00417	1.15e-165	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HLFCFMOD_00418	0.0	-	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	RecG wedge domain
HLFCFMOD_00420	0.0	-	-	-	C	ko:K00184	-	ko00000	4Fe-4S dicluster domain
HLFCFMOD_00421	2.16e-180	-	-	-	C	-	-	-	Cytochrome c7 and related cytochrome c
HLFCFMOD_00422	2.09e-302	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HLFCFMOD_00424	6.34e-255	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Iron-containing alcohol dehydrogenase
HLFCFMOD_00426	1.03e-27	-	-	-	S	-	-	-	Rhomboid family
HLFCFMOD_00427	2.55e-165	-	-	-	S	-	-	-	Rhomboid family
HLFCFMOD_00428	1.03e-266	-	-	-	E	-	-	-	FAD dependent oxidoreductase
HLFCFMOD_00429	2.64e-267	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HLFCFMOD_00432	0.0	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase
HLFCFMOD_00433	2e-120	-	-	-	K	-	-	-	ParB domain protein nuclease
HLFCFMOD_00436	2.63e-115	-	-	-	L	-	-	-	Staphylococcal nuclease homologues
HLFCFMOD_00437	7.66e-245	-	-	-	M	-	-	-	Alginate lyase
HLFCFMOD_00441	7.17e-104	yciA	-	-	I	ko:K10806	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	acyl-coa hydrolase
HLFCFMOD_00442	2.84e-315	hsrA	-	-	EGP	-	-	-	Major facilitator Superfamily
HLFCFMOD_00443	1.41e-289	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HLFCFMOD_00444	2.07e-243	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HLFCFMOD_00445	2.62e-180	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HLFCFMOD_00446	0.0	-	3.2.1.23	-	G	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HLFCFMOD_00447	1.25e-157	-	-	-	C	-	-	-	Nitroreductase family
HLFCFMOD_00448	0.0	-	-	-	E	-	-	-	Transglutaminase-like
HLFCFMOD_00449	5.58e-110	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
HLFCFMOD_00450	6.56e-112	-	-	-	S	ko:K08999	-	ko00000	Bifunctional nuclease
HLFCFMOD_00452	0.0	-	-	-	P	-	-	-	Citrate transporter
HLFCFMOD_00455	1.01e-255	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
HLFCFMOD_00456	0.0	-	-	-	I	-	-	-	Acyltransferase family
HLFCFMOD_00457	1.22e-251	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
HLFCFMOD_00458	1.61e-306	-	-	-	M	-	-	-	Glycosyl transferases group 1
HLFCFMOD_00459	4.21e-204	-	-	-	-	-	-	-	-
HLFCFMOD_00460	2.25e-287	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HLFCFMOD_00461	1.31e-244	-	5.1.3.20	-	M	ko:K03274	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-beta hydroxysteroid dehydrogenase/isomerase family
HLFCFMOD_00462	4.5e-234	-	-	GT9	M	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	ADP-heptose-lipopolysaccharide heptosyltransferase activity
HLFCFMOD_00463	7.08e-251	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HLFCFMOD_00464	4.53e-244	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HLFCFMOD_00465	4.39e-209	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HLFCFMOD_00467	4.03e-239	-	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HLFCFMOD_00468	9.36e-171	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HLFCFMOD_00469	1.17e-218	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
HLFCFMOD_00470	9e-65	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HLFCFMOD_00471	1.15e-86	-	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HLFCFMOD_00472	1.15e-151	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HLFCFMOD_00473	1.19e-256	-	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HLFCFMOD_00474	2.61e-128	-	-	-	-	-	-	-	-
HLFCFMOD_00475	5.05e-233	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HLFCFMOD_00476	2.61e-31	-	-	-	S	-	-	-	NYN domain
HLFCFMOD_00477	7.51e-152	ppaX_1	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
HLFCFMOD_00478	1.58e-138	-	-	-	S	-	-	-	Maltose acetyltransferase
HLFCFMOD_00479	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	GMP synthase C terminal domain
HLFCFMOD_00480	0.0	-	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase / GMP reductase domain
HLFCFMOD_00481	1.43e-120	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HLFCFMOD_00484	3.64e-276	-	-	-	S	-	-	-	Fungal chitosanase of glycosyl hydrolase group 75
HLFCFMOD_00485	9.28e-219	-	2.5.1.21	-	I	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01006	Squalene/phytoene synthase
HLFCFMOD_00486	0.0	-	-	-	KT	ko:K02584	ko02020,map02020	ko00000,ko00001,ko03000	Bacterial regulatory protein, Fis family
HLFCFMOD_00487	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HLFCFMOD_00489	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
HLFCFMOD_00491	0.0	-	-	-	-	-	-	-	-
HLFCFMOD_00492	0.0	-	4.1.1.15	-	E	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase conserved domain
HLFCFMOD_00493	1.74e-140	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HLFCFMOD_00494	0.0	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase alpha chain like domain
HLFCFMOD_00495	4.25e-238	pyrD	1.3.5.2	-	F	ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
HLFCFMOD_00496	4.7e-156	-	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase
HLFCFMOD_00497	1.1e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLFCFMOD_00498	1.63e-164	-	-	-	CO	-	-	-	Thioredoxin-like
HLFCFMOD_00499	0.0	-	-	-	C	-	-	-	Cytochrome c554 and c-prime
HLFCFMOD_00500	1.38e-310	-	-	-	S	-	-	-	PFAM CBS domain containing protein
HLFCFMOD_00501	9.05e-313	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	PFAM CBS domain containing protein
HLFCFMOD_00502	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HLFCFMOD_00503	3.01e-49	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal_S15
HLFCFMOD_00504	8.11e-152	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HLFCFMOD_00505	2.36e-213	-	-	-	D	ko:K19234,ko:K19236	ko01503,map01503	ko00000,ko00001,ko01002,ko01011	ErfK ybiS ycfS ynhG family protein
HLFCFMOD_00506	0.0	-	-	-	S	-	-	-	Terminase
HLFCFMOD_00509	7.54e-201	-	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HLFCFMOD_00510	1.04e-144	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLFCFMOD_00511	9.86e-168	-	-	-	M	-	-	-	Peptidase family M23
HLFCFMOD_00512	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	PFAM coagulation factor 5 8 type domain protein
HLFCFMOD_00514	1.33e-174	-	-	-	NU	-	-	-	Prepilin-type N-terminal cleavage methylation domain
HLFCFMOD_00516	9.93e-180	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HLFCFMOD_00517	0.0	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HLFCFMOD_00518	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
HLFCFMOD_00519	2.13e-56	-	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	AAA domain
HLFCFMOD_00520	3.74e-228	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HLFCFMOD_00521	1.03e-293	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
HLFCFMOD_00522	4.27e-14	-	2.7.11.1	-	T	ko:K08269	ko04136,ko04138,ko04139,ko04140,ko04150,ko04212,map04136,map04138,map04139,map04140,map04150,map04212	ko00000,ko00001,ko01000,ko01001,ko03029,ko04131	Serine threonine-protein kinase
HLFCFMOD_00527	2.01e-05	-	-	-	-	-	-	-	-
HLFCFMOD_00528	1.23e-47	-	-	-	S	-	-	-	Protease prsW family
HLFCFMOD_00530	3.45e-121	-	-	-	-	-	-	-	-
HLFCFMOD_00531	7.14e-185	-	-	-	H	ko:K22132	-	ko00000,ko03016	ThiF family
HLFCFMOD_00532	3.41e-189	-	-	-	S	ko:K09769	-	ko00000	YmdB-like protein
HLFCFMOD_00533	1.56e-103	-	-	-	T	-	-	-	Universal stress protein family
HLFCFMOD_00534	6.9e-232	-	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (W and Y)
HLFCFMOD_00535	1.9e-107	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HLFCFMOD_00536	2.95e-203	-	-	-	GM	-	-	-	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HLFCFMOD_00537	3.69e-166	-	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
HLFCFMOD_00538	8.39e-89	-	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HLFCFMOD_00539	2.57e-223	-	-	-	CO	-	-	-	amine dehydrogenase activity
HLFCFMOD_00540	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
HLFCFMOD_00541	2.46e-215	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
HLFCFMOD_00542	1.45e-74	-	-	-	P	ko:K03972	-	ko00000	Rhodanese Homology Domain
HLFCFMOD_00543	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-L-fucosidase
HLFCFMOD_00544	0.0	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HLFCFMOD_00545	8.21e-246	-	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	ATP:guanido phosphotransferase, C-terminal catalytic domain
HLFCFMOD_00546	5.46e-126	-	-	-	S	ko:K19411	-	ko00000	UvrB/uvrC motif
HLFCFMOD_00547	3.84e-180	-	-	-	P	ko:K09819	-	ko00000,ko00002,ko02000	FecCD transport family
HLFCFMOD_00548	1.77e-191	-	-	-	P	ko:K09820	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HLFCFMOD_00549	2.47e-101	-	-	-	-	-	-	-	-
HLFCFMOD_00550	5.64e-227	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HLFCFMOD_00551	0.0	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
HLFCFMOD_00552	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HLFCFMOD_00553	5.24e-137	leuA	2.3.3.13	-	H	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HLFCFMOD_00555	0.0	-	-	-	V	-	-	-	MatE
HLFCFMOD_00556	4.33e-161	menG	2.1.1.163, 2.1.1.201	-	Q	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	ubiE/COQ5 methyltransferase family
HLFCFMOD_00560	1.25e-199	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HLFCFMOD_00561	3.85e-27	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLFCFMOD_00563	1.46e-204	-	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
HLFCFMOD_00564	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
HLFCFMOD_00565	4.97e-168	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLFCFMOD_00566	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HLFCFMOD_00568	6.2e-155	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HLFCFMOD_00569	1.24e-230	-	-	-	EP	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HLFCFMOD_00570	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
HLFCFMOD_00571	9.67e-251	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
HLFCFMOD_00572	2.31e-127	-	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Recombination protein O N terminal
HLFCFMOD_00573	1.14e-182	-	-	-	S	-	-	-	Tetratricopeptide repeat
HLFCFMOD_00574	0.0	dxs	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HLFCFMOD_00575	3.08e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
HLFCFMOD_00576	0.0	-	-	-	O	-	-	-	C-terminal four TMM region of protein-O-mannosyltransferase
HLFCFMOD_00577	0.0	-	-	-	T	-	-	-	Bacterial regulatory protein, Fis family
HLFCFMOD_00578	7.39e-274	-	-	-	T	-	-	-	PAS domain
HLFCFMOD_00579	3.37e-97	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase superfamily
HLFCFMOD_00580	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	BPG-independent PGAM N-terminus (iPGM_N)
HLFCFMOD_00581	4.16e-85	-	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S12/S23
HLFCFMOD_00582	2.91e-104	-	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S7p/S5e
HLFCFMOD_00583	0.0	-	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HLFCFMOD_00584	3.67e-65	-	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S10p/S20e
HLFCFMOD_00585	3.86e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HLFCFMOD_00586	9.43e-132	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L4/L1 family
HLFCFMOD_00587	8.72e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HLFCFMOD_00588	1.85e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLFCFMOD_00589	1.05e-58	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HLFCFMOD_00590	4.05e-152	-	-	-	-	-	-	-	-
HLFCFMOD_00591	4.97e-70	-	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
HLFCFMOD_00592	5.2e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HLFCFMOD_00593	3.42e-97	-	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HLFCFMOD_00594	2.36e-34	-	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L29 protein
HLFCFMOD_00595	2.19e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HLFCFMOD_00596	6.79e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HLFCFMOD_00598	6.2e-203	-	-	-	-	-	-	-	-
HLFCFMOD_00599	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HLFCFMOD_00600	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
HLFCFMOD_00601	3.33e-254	-	5.2.1.8	-	O	ko:K03771	-	ko00000,ko01000,ko03110	SurA N-terminal domain
HLFCFMOD_00602	9.04e-172	-	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HLFCFMOD_00603	1.43e-142	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HLFCFMOD_00609	1.9e-62	-	-	-	L	-	-	-	bacterial (prokaryotic) histone like domain
HLFCFMOD_00610	1.91e-204	-	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
HLFCFMOD_00611	9.07e-42	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
HLFCFMOD_00612	2.85e-93	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Cell cycle protein
HLFCFMOD_00613	4.56e-266	-	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HLFCFMOD_00614	0.0	murB	-	-	M	-	-	-	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
HLFCFMOD_00615	6.85e-227	ddl	6.3.2.4	-	M	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	D-ala D-ala ligase N-terminus
HLFCFMOD_00616	1.8e-216	-	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	POTRA domain, FtsQ-type
HLFCFMOD_00617	1.15e-238	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLFCFMOD_00618	1.11e-237	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
HLFCFMOD_00619	7.14e-141	-	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HLFCFMOD_00620	0.0	-	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase family (aconitate hydratase)
HLFCFMOD_00621	1.53e-146	-	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
HLFCFMOD_00622	4.99e-274	-	-	-	-	-	-	-	-
HLFCFMOD_00623	0.0	-	-	-	O	-	-	-	Trypsin
HLFCFMOD_00624	0.0	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HLFCFMOD_00625	2.93e-280	-	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate synthase
HLFCFMOD_00627	2.65e-174	-	-	-	E	-	-	-	ATPases associated with a variety of cellular activities
HLFCFMOD_00628	2.05e-198	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HLFCFMOD_00629	5.88e-163	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S2
HLFCFMOD_00630	4.39e-170	cbiX	4.99.1.3	-	S	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	sirohydrochlorin cobaltochelatase activity
HLFCFMOD_00631	6.68e-198	-	2.5.1.55	-	M	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	DAHP synthetase I family
HLFCFMOD_00634	6.31e-171	-	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HLFCFMOD_00635	5.39e-220	-	-	-	E	-	-	-	Phosphoserine phosphatase
HLFCFMOD_00636	0.0	-	6.3.2.45	-	M	ko:K02558	-	ko00000,ko01000	Mur ligase family, catalytic domain
HLFCFMOD_00637	7.64e-307	-	-	-	M	-	-	-	OmpA family
HLFCFMOD_00638	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
HLFCFMOD_00639	2.27e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HLFCFMOD_00640	1.31e-114	ywrF	-	-	S	-	-	-	FMN binding
HLFCFMOD_00641	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HLFCFMOD_00642	0.0	-	-	-	T	-	-	-	pathogenesis
HLFCFMOD_00644	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
HLFCFMOD_00645	7.81e-316	-	-	-	-	-	-	-	-
HLFCFMOD_00646	5.12e-71	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HLFCFMOD_00648	1.1e-160	-	-	-	S	-	-	-	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HLFCFMOD_00649	4.58e-256	-	-	-	M	ko:K02022	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HLFCFMOD_00650	1.7e-301	-	4.2.1.129, 5.4.99.17, 5.5.1.16	-	I	ko:K06045,ko:K17811	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
HLFCFMOD_00651	0.0	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
HLFCFMOD_00652	1.36e-175	-	-	-	-	-	-	-	-
HLFCFMOD_00654	2.58e-225	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HLFCFMOD_00655	0.0	-	-	-	-	-	-	-	-
HLFCFMOD_00656	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HLFCFMOD_00658	3.73e-200	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HLFCFMOD_00659	3.34e-106	-	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
HLFCFMOD_00660	1.93e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal prokaryotic L21 protein
HLFCFMOD_00661	2.14e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
HLFCFMOD_00662	6.78e-100	-	-	-	P	ko:K09825	-	ko00000,ko03000	Ferric uptake regulator family
HLFCFMOD_00663	1.02e-178	-	-	-	O	ko:K09013	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
HLFCFMOD_00664	0.0	-	-	-	O	ko:K09014	-	ko00000	Uncharacterized protein family (UPF0051)
HLFCFMOD_00665	2.04e-293	-	-	-	O	ko:K09015	-	ko00000	Uncharacterized protein family (UPF0051)
HLFCFMOD_00666	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
HLFCFMOD_00667	0.0	-	-	-	P	-	-	-	Sulfatase
HLFCFMOD_00668	1.77e-234	-	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Biotin and Thiamin Synthesis associated domain
HLFCFMOD_00669	0.0	-	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HLFCFMOD_00672	1.93e-77	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
HLFCFMOD_00673	1.08e-73	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
HLFCFMOD_00674	1.95e-222	-	-	-	M	-	-	-	Glycosyl transferase family 2
HLFCFMOD_00675	2.98e-115	flmH	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HLFCFMOD_00676	5.18e-283	-	2.6.1.59	-	M	ko:K02805	-	ko00000,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HLFCFMOD_00677	4.27e-275	-	-	-	S	-	-	-	COGs COG4299 conserved
HLFCFMOD_00678	8.17e-124	sprT	-	-	K	-	-	-	SprT-like family
HLFCFMOD_00679	1.38e-139	-	-	-	-	-	-	-	-
HLFCFMOD_00680	5.04e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HLFCFMOD_00681	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HLFCFMOD_00682	4.5e-201	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HLFCFMOD_00683	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HLFCFMOD_00684	1.59e-86	-	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase delta (OSCP) subunit
HLFCFMOD_00685	4.38e-78	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase B/B' CF(0)
HLFCFMOD_00686	1.65e-11	-	-	-	S	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	PFAM H transporting two-sector ATPase C subunit
HLFCFMOD_00687	6.27e-219	-	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	ATP synthase A chain
HLFCFMOD_00688	0.0	-	-	-	-	-	-	-	-
HLFCFMOD_00689	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein dimerisation domain
HLFCFMOD_00690	5.1e-153	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HLFCFMOD_00691	2.55e-270	-	-	-	S	-	-	-	COGs COG4299 conserved
HLFCFMOD_00692	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
HLFCFMOD_00694	4.09e-218	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HLFCFMOD_00695	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HLFCFMOD_00699	7.13e-276	-	-	-	G	-	-	-	Major Facilitator Superfamily
HLFCFMOD_00700	5.49e-85	nuoA	1.6.5.3	-	C	ko:K00330	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HLFCFMOD_00702	3.96e-197	supH	-	-	Q	-	-	-	phosphatase activity
HLFCFMOD_00703	0.0	legA	3.5.1.2	-	G	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	response to abiotic stimulus
HLFCFMOD_00704	0.0	-	-	-	EG	-	-	-	BNR repeat-like domain
HLFCFMOD_00705	3.84e-188	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
HLFCFMOD_00706	9.83e-190	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
HLFCFMOD_00707	0.0	-	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HLFCFMOD_00708	3.17e-190	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
HLFCFMOD_00709	0.0	-	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Glycosyltransferase family 9 (heptosyltransferase)
HLFCFMOD_00710	6.47e-29	-	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
HLFCFMOD_00711	1.87e-292	-	2.3.1.31	-	E	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko01000	alpha/beta hydrolase fold
HLFCFMOD_00712	2.25e-91	-	-	-	O	-	-	-	response to oxidative stress
HLFCFMOD_00713	0.0	-	-	-	T	-	-	-	pathogenesis
HLFCFMOD_00715	6.37e-187	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HLFCFMOD_00716	7.27e-287	-	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HLFCFMOD_00717	3.43e-154	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
HLFCFMOD_00718	2.77e-176	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
HLFCFMOD_00719	0.0	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HLFCFMOD_00720	0.0	-	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HLFCFMOD_00724	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
HLFCFMOD_00725	4.94e-245	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HLFCFMOD_00726	8.42e-184	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HLFCFMOD_00727	2.55e-247	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HLFCFMOD_00728	9.06e-189	-	-	-	-	-	-	-	-
HLFCFMOD_00729	1.46e-123	-	-	-	NU	ko:K02457,ko:K08084	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	protein transport across the cell outer membrane
HLFCFMOD_00731	2.39e-224	-	-	-	M	ko:K07276	-	ko00000	Mitochondrial fission ELM1
HLFCFMOD_00732	3.9e-270	-	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
HLFCFMOD_00733	1.11e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLFCFMOD_00734	2.11e-121	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HLFCFMOD_00735	4.36e-142	-	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S4/S9 N-terminal domain
HLFCFMOD_00736	5.71e-191	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
HLFCFMOD_00740	1.07e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLFCFMOD_00741	0.0	-	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
HLFCFMOD_00742	5.92e-289	-	3.5.1.42	-	S	ko:K03742	ko00760,map00760	ko00000,ko00001,ko01000	Competence-damaged protein
HLFCFMOD_00743	6.87e-153	-	-	-	O	-	-	-	methyltransferase activity
HLFCFMOD_00744	3.22e-182	-	-	-	U	ko:K20276	ko02024,map02024	ko00000,ko00001	domain, Protein
HLFCFMOD_00745	0.0	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
HLFCFMOD_00746	8.76e-261	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Elongator protein 3, MiaB family, Radical SAM
HLFCFMOD_00747	1.1e-197	-	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SRP54-type protein, GTPase domain
HLFCFMOD_00748	9.48e-205	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLFCFMOD_00749	4.95e-103	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HLFCFMOD_00750	4.76e-288	-	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase II
HLFCFMOD_00751	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), anti-codon binding domain
HLFCFMOD_00752	0.0	-	-	-	-	-	-	-	-
HLFCFMOD_00753	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HLFCFMOD_00754	3.99e-258	-	-	-	S	-	-	-	ankyrin repeats
HLFCFMOD_00755	1.05e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HLFCFMOD_00756	1.06e-44	-	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S21
HLFCFMOD_00757	0.0	-	2.7.1.167, 2.7.7.70	-	M	ko:K03272	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	pfkB family carbohydrate kinase
HLFCFMOD_00758	8.25e-131	-	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
HLFCFMOD_00759	1.03e-116	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Polynucleotide kinase 3 phosphatase
HLFCFMOD_00760	1.26e-222	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
HLFCFMOD_00762	6.06e-251	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
HLFCFMOD_00763	1.63e-189	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLFCFMOD_00764	1.4e-195	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLFCFMOD_00765	2.31e-187	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HLFCFMOD_00766	1.48e-120	-	-	-	M	ko:K06142	-	ko00000	Outer membrane protein (OmpH-like)
HLFCFMOD_00767	3.42e-196	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HLFCFMOD_00768	6.38e-151	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLFCFMOD_00769	4.78e-63	-	-	-	-	-	-	-	-
HLFCFMOD_00770	1.19e-57	-	-	-	-	-	-	-	-
HLFCFMOD_00771	8.41e-202	-	-	-	S	-	-	-	DisA bacterial checkpoint controller nucleotide-binding
HLFCFMOD_00774	2.25e-60	-	-	-	P	-	-	-	Cation transport protein
HLFCFMOD_00775	3.52e-161	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HLFCFMOD_00776	0.0	-	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Oligonucleotide/oligosaccharide-binding (OB)-fold
HLFCFMOD_00777	7.97e-108	-	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HLFCFMOD_00778	0.0	-	-	-	O	-	-	-	Trypsin
HLFCFMOD_00779	4.27e-273	-	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
HLFCFMOD_00780	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HLFCFMOD_00781	6.45e-266	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	RibD C-terminal domain
HLFCFMOD_00782	4.01e-157	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
HLFCFMOD_00784	1.45e-258	-	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLFCFMOD_00786	3.01e-252	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HLFCFMOD_00787	0.0	-	-	-	V	-	-	-	MatE
HLFCFMOD_00788	4.33e-180	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HLFCFMOD_00789	2.63e-84	-	-	-	M	-	-	-	Lysin motif
HLFCFMOD_00790	4.37e-203	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HLFCFMOD_00791	1.03e-265	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2219)
HLFCFMOD_00792	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
HLFCFMOD_00793	2.66e-06	-	-	-	-	-	-	-	-
HLFCFMOD_00795	0.0	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
HLFCFMOD_00796	2.4e-167	-	-	-	T	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HLFCFMOD_00798	0.0	-	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HLFCFMOD_00799	0.0	-	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HLFCFMOD_00800	6.76e-131	-	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HLFCFMOD_00801	1.76e-79	-	-	-	S	-	-	-	PFAM Cupin 2 conserved barrel domain protein
HLFCFMOD_00802	1.34e-232	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HLFCFMOD_00803	0.0	-	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	C-terminal, D2-small domain, of ClpB protein
HLFCFMOD_00804	1.8e-105	-	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
HLFCFMOD_00805	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Collagenase
HLFCFMOD_00807	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HLFCFMOD_00809	1.14e-161	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLFCFMOD_00810	4.16e-14	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
HLFCFMOD_00811	1.71e-27	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
HLFCFMOD_00812	4.61e-19	-	-	-	-	-	-	-	-
HLFCFMOD_00813	0.0	hsdR	3.1.21.3	-	F	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HLFCFMOD_00814	3.86e-122	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HLFCFMOD_00815	1.32e-196	-	-	-	V	-	-	-	AAA domain
HLFCFMOD_00816	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	subunit M
HLFCFMOD_00817	6.52e-75	-	-	-	L	-	-	-	Cupin 2, conserved barrel domain protein
HLFCFMOD_00818	7.1e-130	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
HLFCFMOD_00820	3.53e-295	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HLFCFMOD_00821	2.75e-214	-	-	-	K	-	-	-	LysR substrate binding domain
HLFCFMOD_00822	1.17e-271	-	-	-	S	-	-	-	tRNA-splicing ligase RtcB
HLFCFMOD_00823	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HLFCFMOD_00826	1.77e-284	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLFCFMOD_00828	2.93e-125	-	-	-	D	-	-	-	ErfK ybiS ycfS ynhG family protein
HLFCFMOD_00829	0.0	-	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
HLFCFMOD_00830	8.8e-169	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HLFCFMOD_00834	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Bacterial DNA topoisomeraes I ATP-binding domain
HLFCFMOD_00835	7.84e-101	-	-	-	-	-	-	-	-
HLFCFMOD_00836	0.0	-	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase HemD
HLFCFMOD_00837	6.42e-101	-	-	-	S	-	-	-	peptidase
HLFCFMOD_00838	3e-171	-	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HLFCFMOD_00839	3.48e-98	-	-	-	S	-	-	-	peptidase
HLFCFMOD_00840	1.87e-144	-	-	-	S	-	-	-	pathogenesis
HLFCFMOD_00841	1.72e-87	-	-	-	M	ko:K02847,ko:K13009,ko:K16705	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
HLFCFMOD_00842	8.67e-85	-	-	-	S	-	-	-	Protein of unknown function, DUF488
HLFCFMOD_00843	2.07e-235	-	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Porphobilinogen deaminase, dipyromethane cofactor binding domain
HLFCFMOD_00844	1.07e-240	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Glutamyl-tRNAGlu reductase, N-terminal domain
HLFCFMOD_00845	1.19e-177	-	-	-	S	-	-	-	Cytochrome C assembly protein
HLFCFMOD_00846	3.84e-189	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Type I GTP cyclohydrolase folE2
HLFCFMOD_00847	4.52e-49	-	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S18
HLFCFMOD_00848	5.67e-33	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HLFCFMOD_00849	1.46e-118	-	-	-	T	-	-	-	Prokaryotic dksA/traR C4-type zinc finger
HLFCFMOD_00850	1.69e-231	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HLFCFMOD_00851	1.16e-244	sun	2.1.1.176, 2.1.1.178	-	J	ko:K03500,ko:K11392	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HLFCFMOD_00852	1.03e-121	-	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HLFCFMOD_00853	2.34e-97	nudI	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	GDP-mannose mannosyl hydrolase activity
HLFCFMOD_00855	2.88e-283	-	-	-	M	ko:K02005	-	ko00000	HlyD family secretion protein
HLFCFMOD_00856	2.12e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLFCFMOD_00857	3.42e-313	-	-	-	V	-	-	-	MacB-like periplasmic core domain
HLFCFMOD_00858	3.64e-316	-	-	-	MU	-	-	-	Outer membrane efflux protein
HLFCFMOD_00859	6.41e-284	-	-	-	V	-	-	-	Beta-lactamase
HLFCFMOD_00860	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HLFCFMOD_00861	1.16e-280	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HLFCFMOD_00862	2.91e-94	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HLFCFMOD_00863	1.45e-164	-	-	-	S	-	-	-	Uncharacterised protein family UPF0066
HLFCFMOD_00864	5.56e-306	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydro-orotase-like
HLFCFMOD_00865	3.12e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
HLFCFMOD_00866	1.15e-122	-	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Phosphoribosyl transferase domain
HLFCFMOD_00867	3.73e-90	-	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR carboxylase
HLFCFMOD_00869	0.0	-	-	-	H	ko:K07137	-	ko00000	5-formyltetrahydrofolate cyclo-ligase activity
HLFCFMOD_00870	2.63e-267	-	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
HLFCFMOD_00871	2.11e-89	-	-	-	-	-	-	-	-
HLFCFMOD_00872	0.0	rseP	3.4.21.116	-	M	ko:K06399,ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	metalloendopeptidase activity
HLFCFMOD_00873	1.7e-297	-	-	-	S	-	-	-	AI-2E family transporter
HLFCFMOD_00874	0.0	-	-	-	P	-	-	-	Domain of unknown function
HLFCFMOD_00876	1.52e-81	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HLFCFMOD_00877	4.75e-314	-	-	-	G	-	-	-	cellulose 1,4-beta-cellobiosidase activity
HLFCFMOD_00878	2.72e-186	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HLFCFMOD_00880	3.52e-295	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
HLFCFMOD_00881	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
HLFCFMOD_00882	3.42e-111	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
HLFCFMOD_00884	1.86e-94	-	-	-	O	-	-	-	OsmC-like protein
HLFCFMOD_00885	0.0	-	-	-	CO	-	-	-	Disulphide bond corrector protein DsbC
HLFCFMOD_00886	3.47e-119	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HLFCFMOD_00887	7.58e-140	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease
HLFCFMOD_00888	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HLFCFMOD_00889	6.51e-45	-	-	-	KT	-	-	-	Magnesium chelatase, subunit ChlI
HLFCFMOD_00892	3.76e-08	-	-	-	S	-	-	-	Ankyrin repeats (many copies)
HLFCFMOD_00894	4.24e-21	-	-	-	U	-	-	-	Protein of unknown function DUF262
HLFCFMOD_00900	8.78e-16	-	-	-	-	-	-	-	-
HLFCFMOD_00902	4.69e-79	rsfS	-	-	S	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HLFCFMOD_00903	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLFCFMOD_00905	2.6e-257	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
HLFCFMOD_00906	4.36e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Enoyl-CoA hydratase/isomerase
HLFCFMOD_00909	1.07e-301	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	efflux transmembrane transporter activity
HLFCFMOD_00913	9.85e-147	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HLFCFMOD_00916	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
HLFCFMOD_00917	8.38e-98	-	-	-	-	-	-	-	-
HLFCFMOD_00918	9e-192	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
HLFCFMOD_00919	6.18e-262	-	-	-	M	ko:K02847,ko:K13009	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
HLFCFMOD_00920	6.19e-201	-	-	-	S	-	-	-	Glycosyl transferase family 11
HLFCFMOD_00921	3.24e-250	-	-	-	M	-	-	-	Glycosyl transferases group 1
HLFCFMOD_00922	6.11e-278	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HLFCFMOD_00923	4.87e-281	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HLFCFMOD_00924	0.0	-	-	-	-	-	-	-	-
HLFCFMOD_00925	2.67e-113	-	-	-	S	ko:K03818	-	ko00000,ko01000	maltose O-acetyltransferase activity
HLFCFMOD_00926	1.42e-209	-	-	-	M	-	-	-	PFAM glycosyl transferase family 2
HLFCFMOD_00927	6.17e-237	-	-	-	M	-	-	-	Glycosyl transferase, family 2
HLFCFMOD_00928	1.58e-25	-	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
HLFCFMOD_00929	8.91e-123	-	-	-	C	-	-	-	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HLFCFMOD_00930	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
HLFCFMOD_00931	3.66e-229	-	-	-	C	-	-	-	Nitroreductase family
HLFCFMOD_00932	0.0	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HLFCFMOD_00934	1.25e-283	-	-	-	S	-	-	-	very-long-chain-acyl-CoA dehydrogenase activity
HLFCFMOD_00935	2.93e-93	-	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
HLFCFMOD_00936	2.71e-303	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HLFCFMOD_00937	0.0	-	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
HLFCFMOD_00938	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HLFCFMOD_00940	2.48e-315	-	1.1.1.40	-	C	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Malic enzyme, NAD binding domain
HLFCFMOD_00941	0.0	-	-	-	I	ko:K06889,ko:K09914	-	ko00000	PFAM Prenyltransferase squalene oxidase
HLFCFMOD_00942	9.81e-230	exsH	3.2.1.178, 3.2.1.18, 3.2.1.52	GH16,GH20,GH33	G	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	xyloglucan:xyloglucosyl transferase activity
HLFCFMOD_00943	2.6e-259	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
HLFCFMOD_00944	9.25e-128	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLFCFMOD_00945	3.72e-158	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HLFCFMOD_00946	0.0	yidC	-	-	O	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	serine-type endopeptidase activity
HLFCFMOD_00947	4.38e-266	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HLFCFMOD_00948	3.88e-237	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Leucyl-tRNA synthetase, Domain 2
HLFCFMOD_00949	2.22e-151	-	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3 epimerase family
HLFCFMOD_00950	2.57e-220	-	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Phosphatidylserine decarboxylase
HLFCFMOD_00951	1.5e-198	-	-	-	S	-	-	-	metallopeptidase activity
HLFCFMOD_00952	0.0	-	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HLFCFMOD_00953	2.84e-142	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HLFCFMOD_00954	7.84e-42	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S20
HLFCFMOD_00956	1.31e-289	-	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	LytB protein
HLFCFMOD_00957	8.69e-261	-	-	-	J	ko:K05541	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLFCFMOD_00958	6.93e-284	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HLFCFMOD_00959	1.3e-202	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HLFCFMOD_00960	8.33e-182	-	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HLFCFMOD_00961	7.21e-203	folD	1.5.1.5, 3.5.4.9	-	H	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLFCFMOD_00962	7.21e-183	-	-	-	S	ko:K09778	-	ko00000	Domain of unknown function (DUF374)
HLFCFMOD_00963	0.0	-	-	-	-	-	-	-	-
HLFCFMOD_00964	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
HLFCFMOD_00965	0.0	-	-	-	G	-	-	-	Alpha amylase, catalytic domain
HLFCFMOD_00966	0.0	-	2.7.7.19	-	J	ko:K00970	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Poly A polymerase head domain
HLFCFMOD_00967	6.84e-311	-	-	-	O	-	-	-	peroxiredoxin activity
HLFCFMOD_00968	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HLFCFMOD_00969	0.0	-	3.6.4.13	-	L	ko:K03579	-	ko00000,ko01000	ATP-dependent helicase C-terminal
HLFCFMOD_00970	2.31e-215	-	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
HLFCFMOD_00971	0.0	-	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	tail specific protease
HLFCFMOD_00972	0.0	-	-	-	E	-	-	-	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HLFCFMOD_00975	1.52e-186	-	3.4.13.22	-	M	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-ala-D-ala dipeptidase
HLFCFMOD_00976	0.0	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HLFCFMOD_00979	6.05e-86	-	-	-	S	ko:K09922	-	ko00000	Putative member of DMT superfamily (DUF486)
HLFCFMOD_00980	1.87e-212	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HLFCFMOD_00981	6.51e-217	-	-	-	EP	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLFCFMOD_00982	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HLFCFMOD_00983	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HLFCFMOD_00984	1.53e-219	-	-	-	O	-	-	-	Thioredoxin-like domain
HLFCFMOD_00985	1.86e-310	-	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase C-terminal domain
HLFCFMOD_00986	7.11e-235	-	-	-	S	ko:K01128	-	ko00000,ko01000	acid phosphatase activity
HLFCFMOD_00990	0.0	-	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Tubulin/FtsZ family, GTPase domain
HLFCFMOD_00991	3.38e-294	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HLFCFMOD_00992	1.72e-147	-	-	-	M	-	-	-	NLP P60 protein
HLFCFMOD_00993	0.0	-	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
HLFCFMOD_00994	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
HLFCFMOD_00995	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
HLFCFMOD_00996	0.0	-	-	-	H	-	-	-	NAD synthase
HLFCFMOD_00997	4.54e-173	-	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease MlaE
HLFCFMOD_00998	1.75e-189	-	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLFCFMOD_00999	3.28e-232	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MlaD protein
HLFCFMOD_01000	2.69e-38	-	-	-	T	-	-	-	ribosome binding
HLFCFMOD_01003	5.1e-265	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HLFCFMOD_01004	3.71e-260	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HLFCFMOD_01005	3.36e-248	ppiD	5.2.1.8	-	O	ko:K03769,ko:K03770,ko:K03771,ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl cis-trans isomerase activity
HLFCFMOD_01007	0.0	-	-	-	-	-	-	-	-
HLFCFMOD_01008	2.4e-180	kdsB	2.7.7.38	-	M	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HLFCFMOD_01009	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HLFCFMOD_01010	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
HLFCFMOD_01011	3.37e-249	-	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
HLFCFMOD_01012	4.46e-148	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HLFCFMOD_01014	7.55e-142	-	-	-	M	-	-	-	Polysaccharide biosynthesis/export protein
HLFCFMOD_01015	0.0	-	-	-	D	-	-	-	Chain length determinant protein
HLFCFMOD_01016	8.04e-298	-	-	-	-	-	-	-	-
HLFCFMOD_01020	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HLFCFMOD_01021	5.31e-99	-	-	-	S	-	-	-	peptidase
HLFCFMOD_01022	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HLFCFMOD_01023	2.2e-61	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HLFCFMOD_01024	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	MreB/Mbl protein
HLFCFMOD_01025	0.0	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HLFCFMOD_01026	1.14e-279	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
HLFCFMOD_01027	3.59e-241	-	-	-	O	ko:K04655	-	ko00000	AIR synthase related protein, N-terminal domain
HLFCFMOD_01028	1.91e-262	-	-	-	O	ko:K04654	-	ko00000	Hydrogenase formation hypA family
HLFCFMOD_01029	3.9e-50	-	-	-	O	ko:K04653	-	ko00000	HupF/HypC family
HLFCFMOD_01030	0.0	-	-	-	O	ko:K04656	-	ko00000	HypF finger
HLFCFMOD_01031	3.54e-176	hypB	-	-	KO	ko:K04652	-	ko00000,ko03110	CobW/HypB/UreG, nucleotide-binding domain
HLFCFMOD_01032	2.46e-309	-	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
HLFCFMOD_01033	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HLFCFMOD_01037	9.45e-261	-	2.3.1.47	-	H	ko:K00652	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HLFCFMOD_01038	1.15e-281	-	-	-	IQ	-	-	-	Beta-ketoacyl synthase, C-terminal domain
HLFCFMOD_01039	0.0	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	thiolester hydrolase activity
HLFCFMOD_01040	9.61e-290	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HLFCFMOD_01041	9.93e-71	-	-	-	S	-	-	-	Imelysin
HLFCFMOD_01042	0.0	-	-	-	C	-	-	-	Di-haem oxidoreductase, putative peroxidase
HLFCFMOD_01043	1.71e-264	-	-	-	J	-	-	-	Endoribonuclease L-PSP
HLFCFMOD_01044	2.65e-220	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
HLFCFMOD_01045	4.99e-228	fatC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
HLFCFMOD_01046	4.31e-180	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLFCFMOD_01047	4.88e-209	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion transport
HLFCFMOD_01048	1.74e-181	ccs1	-	-	O	ko:K07399	-	ko00000	cytochrome c biogenesis protein
HLFCFMOD_01049	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
HLFCFMOD_01050	6.92e-235	-	-	-	S	-	-	-	Acyltransferase family
HLFCFMOD_01051	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
HLFCFMOD_01052	4.58e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
HLFCFMOD_01053	4.64e-52	-	-	-	C	-	-	-	4Fe-4S single cluster domain of Ferredoxin I
HLFCFMOD_01054	0.0	-	-	GT2	M	ko:K03820	-	ko00000,ko01000	Carbon-nitrogen hydrolase
HLFCFMOD_01055	4.47e-176	-	-	-	S	-	-	-	Phosphodiester glycosidase
HLFCFMOD_01056	5.9e-233	-	2.7.7.13	-	JM	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HLFCFMOD_01057	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
HLFCFMOD_01058	1.75e-229	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HLFCFMOD_01059	2.1e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLFCFMOD_01060	1.48e-275	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HLFCFMOD_01065	6.72e-210	-	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HLFCFMOD_01066	5.72e-271	-	2.1.1.72	-	H	ko:K07318	-	ko00000,ko01000,ko02048	PFAM D12 class N6 adenine-specific DNA methyltransferase
HLFCFMOD_01068	2.08e-240	BT0173	-	-	S	-	-	-	Psort location Cytoplasmic, score
HLFCFMOD_01069	1.06e-169	BT0174	-	-	C	ko:K04488	-	ko00000	iron-sulfur transferase activity
HLFCFMOD_01070	5.74e-200	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HLFCFMOD_01072	8.29e-100	cysJ	1.8.1.2	-	C	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	hydroxylamine reductase activity
HLFCFMOD_01074	6.87e-148	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HLFCFMOD_01075	1.09e-135	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HLFCFMOD_01076	3.4e-173	-	-	-	S	-	-	-	peptidoglycan biosynthetic process
HLFCFMOD_01077	1.3e-206	-	1.4.1.16	-	S	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HLFCFMOD_01079	0.000103	-	-	-	S	-	-	-	Entericidin EcnA/B family
HLFCFMOD_01080	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HLFCFMOD_01081	3.01e-133	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	reductase
HLFCFMOD_01082	7.12e-152	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HLFCFMOD_01083	7.99e-78	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HLFCFMOD_01084	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
HLFCFMOD_01085	1.5e-296	lpxK	2.7.1.130	-	M	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
HLFCFMOD_01086	4.56e-139	-	-	-	S	ko:K07164	-	ko00000	C4-type zinc ribbon domain
HLFCFMOD_01087	3.18e-264	-	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
HLFCFMOD_01088	3.68e-75	-	-	-	-	-	-	-	-
HLFCFMOD_01089	4.15e-191	-	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	MazG nucleotide pyrophosphohydrolase domain
HLFCFMOD_01090	2.92e-70	-	-	-	-	-	-	-	-
HLFCFMOD_01091	3.42e-180	-	-	-	S	-	-	-	competence protein
HLFCFMOD_01092	1.67e-100	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HLFCFMOD_01096	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Sulfatase
HLFCFMOD_01097	1.3e-143	-	-	-	-	-	-	-	-
HLFCFMOD_01098	9.08e-165	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HLFCFMOD_01099	4.82e-178	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLFCFMOD_01100	2.71e-300	-	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	16S rRNA methyltransferase RsmB/F
HLFCFMOD_01101	9.39e-117	-	3.1.6.8	-	P	ko:K01134	ko00600,ko04142,map00600,map04142	ko00000,ko00001,ko01000	COG3119 Arylsulfatase A
HLFCFMOD_01102	2.9e-316	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Arginosuccinate synthase
HLFCFMOD_01104	2.79e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLFCFMOD_01105	8.43e-59	-	-	-	S	-	-	-	Zinc ribbon domain
HLFCFMOD_01106	4.77e-310	-	-	-	S	-	-	-	PFAM CBS domain containing protein
HLFCFMOD_01107	2.06e-150	-	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
HLFCFMOD_01108	2.8e-81	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
HLFCFMOD_01110	2.27e-175	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
HLFCFMOD_01111	7.36e-174	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
HLFCFMOD_01113	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HLFCFMOD_01114	4.11e-08	-	-	-	M	-	-	-	major outer membrane lipoprotein
HLFCFMOD_01116	4.21e-137	-	-	-	J	ko:K05808	-	ko00000,ko03009	Sigma 54 modulation/S30EA ribosomal protein C terminus
HLFCFMOD_01118	3.57e-28	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HLFCFMOD_01119	2.95e-159	-	-	-	IQ	-	-	-	Short chain dehydrogenase
HLFCFMOD_01120	5.83e-310	-	-	-	C	-	-	-	Carboxymuconolactone decarboxylase family
HLFCFMOD_01121	5.85e-275	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HLFCFMOD_01122	2.06e-186	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HLFCFMOD_01123	1.05e-178	-	-	-	C	-	-	-	aldo keto reductase
HLFCFMOD_01124	1.55e-221	-	-	-	K	-	-	-	Transcriptional regulator
HLFCFMOD_01125	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HLFCFMOD_01126	2.55e-306	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HLFCFMOD_01127	1.66e-304	-	-	-	C	-	-	-	4 iron, 4 sulfur cluster binding
HLFCFMOD_01128	4.44e-110	-	-	-	KT	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
HLFCFMOD_01129	2.59e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
HLFCFMOD_01130	3.79e-182	-	-	-	-	-	-	-	-
HLFCFMOD_01131	2.33e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
HLFCFMOD_01132	1.24e-51	-	-	-	-	-	-	-	-
HLFCFMOD_01134	1.46e-75	-	-	-	S	ko:K09954	-	ko00000	Putative quorum-sensing-regulated virulence factor
HLFCFMOD_01135	5.94e-178	-	4.2.99.20	-	I	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
HLFCFMOD_01136	1.69e-129	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
HLFCFMOD_01140	3.56e-234	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
HLFCFMOD_01143	7.48e-188	-	-	-	O	ko:K04083	-	ko00000,ko03110	Hsp33 protein
HLFCFMOD_01144	3.62e-121	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLFCFMOD_01145	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HLFCFMOD_01146	9.28e-139	-	-	-	-	-	-	-	-
HLFCFMOD_01147	3.16e-160	-	-	-	S	ko:K07126,ko:K13582	ko04112,map04112	ko00000,ko00001	beta-lactamase activity
HLFCFMOD_01148	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
HLFCFMOD_01149	2.1e-06	-	-	-	-	-	-	-	-
HLFCFMOD_01150	0.0	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HLFCFMOD_01151	0.0	-	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
HLFCFMOD_01154	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
HLFCFMOD_01156	1.87e-215	-	-	-	K	-	-	-	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HLFCFMOD_01157	1.73e-123	paiA	-	-	K	-	-	-	acetyltransferase
HLFCFMOD_01158	2.86e-226	-	-	-	CO	-	-	-	Redoxin
HLFCFMOD_01159	5.74e-86	-	-	-	K	ko:K07343	-	ko00000	positive regulation of type IV pilus biogenesis
HLFCFMOD_01160	1.23e-175	-	6.3.5.11, 6.3.5.9	-	V	ko:K02224,ko:K18554	ko00860,ko01100,ko01120,map00860,map01100,map01120	br01600,ko00000,ko00001,ko01000,ko01504	Chloramphenicol phosphotransferase-like protein
HLFCFMOD_01162	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HLFCFMOD_01163	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLFCFMOD_01164	3.58e-251	-	2.3.1.1	-	E	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
HLFCFMOD_01166	2.38e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	nUDIX hydrolase
HLFCFMOD_01167	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HLFCFMOD_01168	1.09e-223	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HLFCFMOD_01169	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HLFCFMOD_01170	2e-82	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HLFCFMOD_01171	0.0	-	-	-	P	-	-	-	PA14 domain
HLFCFMOD_01172	2.76e-151	-	-	-	-	-	-	-	-
HLFCFMOD_01173	0.0	-	-	-	T	-	-	-	5TM C-terminal transporter carbon starvation CstA
HLFCFMOD_01174	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
HLFCFMOD_01175	4.05e-135	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLFCFMOD_01176	4.34e-284	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HLFCFMOD_01177	6.83e-231	-	-	-	C	-	-	-	e3 binding domain
HLFCFMOD_01178	3.93e-128	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HLFCFMOD_01179	2.16e-265	-	-	-	S	-	-	-	PFAM glycosyl transferase family 2
HLFCFMOD_01180	3.23e-290	-	-	-	-	-	-	-	-
HLFCFMOD_01181	4.88e-263	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HLFCFMOD_01182	3.06e-226	-	-	-	S	-	-	-	Glycosyl transferase family 11
HLFCFMOD_01183	8.96e-274	-	-	GT2	S	ko:K19427	-	ko00000,ko01000	PFAM glycosyl transferase family 2
HLFCFMOD_01185	1.02e-281	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HLFCFMOD_01186	0.0	-	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Polyphosphate kinase middle domain
HLFCFMOD_01187	0.0	-	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HLFCFMOD_01188	8.13e-264	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HLFCFMOD_01189	1.29e-192	map	3.4.11.18	-	J	ko:K01265	-	ko00000,ko01000,ko01002	Metallopeptidase family M24
HLFCFMOD_01190	6.41e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HLFCFMOD_01191	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLFCFMOD_01193	6.42e-101	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
HLFCFMOD_01194	7.93e-104	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HLFCFMOD_01195	3.68e-146	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Amino acid kinase family
HLFCFMOD_01196	5.11e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HLFCFMOD_01197	9.17e-70	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
HLFCFMOD_01198	7.2e-103	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HLFCFMOD_01199	1.44e-229	-	-	-	J	-	-	-	Belongs to the universal ribosomal protein uS2 family
HLFCFMOD_01200	6.58e-225	-	-	-	L	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HLFCFMOD_01201	1.52e-16	-	-	-	C	-	-	-	Nitroreductase family
HLFCFMOD_01202	1.37e-94	-	-	-	C	-	-	-	Nitroreductase family
HLFCFMOD_01203	6.31e-105	-	-	-	EG	-	-	-	membrane
HLFCFMOD_01204	2.84e-35	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HLFCFMOD_01205	3.88e-152	-	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HLFCFMOD_01206	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
HLFCFMOD_01208	7.65e-101	-	-	-	M	ko:K06077	-	ko00000	Glycine zipper 2TM domain
HLFCFMOD_01209	2.5e-233	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HLFCFMOD_01210	2.57e-140	-	-	-	P	ko:K02039	-	ko00000	PhoU domain
HLFCFMOD_01211	6.37e-186	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLFCFMOD_01212	1.51e-221	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	PBP superfamily domain
HLFCFMOD_01213	0.0	pstC	-	-	P	ko:K02037,ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLFCFMOD_01214	0.0	-	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLFCFMOD_01215	4.85e-185	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLFCFMOD_01216	8.01e-153	phoU	-	-	P	ko:K02039	-	ko00000	negative regulation of phosphate transmembrane transport
HLFCFMOD_01217	1.31e-214	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HLFCFMOD_01218	8.78e-172	-	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Phosphoadenosine phosphosulfate reductase family
HLFCFMOD_01219	1.73e-216	-	2.7.7.4	-	EH	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoadenosine phosphosulfate reductase family
HLFCFMOD_01220	0.0	-	2.7.1.25, 2.7.7.4	-	P	ko:K00955	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
HLFCFMOD_01221	6.15e-260	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
HLFCFMOD_01222	2.4e-188	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLFCFMOD_01223	1.89e-182	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HLFCFMOD_01224	0.0	-	1.8.1.2	-	P	ko:K00381	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite and sulphite reductase 4Fe-4S domain
HLFCFMOD_01226	8.5e-225	-	-	-	J	-	-	-	PFAM Endoribonuclease L-PSP
HLFCFMOD_01227	2.82e-198	-	-	-	P	-	-	-	Sulfatase
HLFCFMOD_01228	1.64e-223	-	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HLFCFMOD_01229	5.06e-94	-	-	-	S	ko:K02426	-	ko00000	Fe-S metabolism associated domain
HLFCFMOD_01231	0.0	-	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha amylase, C-terminal all-beta domain
HLFCFMOD_01232	1.45e-262	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
HLFCFMOD_01233	0.0	cobD	2.6.1.9, 2.7.7.74, 4.1.1.81	-	M	ko:K00817,ko:K04720,ko:K07281	ko00340,ko00350,ko00360,ko00400,ko00401,ko00562,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00562,map00860,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	nucleotidyl transferase
HLFCFMOD_01234	7.48e-96	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
HLFCFMOD_01235	0.0	-	2.7.7.15	-	H	ko:K00968	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HLFCFMOD_01236	2.54e-226	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
HLFCFMOD_01237	3.44e-132	-	-	-	S	-	-	-	protein trimerization
HLFCFMOD_01239	8.74e-182	-	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
HLFCFMOD_01240	0.0	-	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP--glucose-1-phosphate uridylyltransferase
HLFCFMOD_01241	1.01e-124	-	-	-	-	-	-	-	-
HLFCFMOD_01242	1.12e-63	-	-	-	J	-	-	-	RF-1 domain
HLFCFMOD_01243	1.47e-121	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HLFCFMOD_01244	6.64e-279	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
HLFCFMOD_01245	3.69e-297	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HLFCFMOD_01246	3.48e-43	-	-	-	K	-	-	-	-acetyltransferase
HLFCFMOD_01247	1.15e-146	-	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HLFCFMOD_01248	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLFCFMOD_01250	5.7e-236	-	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
HLFCFMOD_01252	2.04e-160	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HLFCFMOD_01253	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HLFCFMOD_01254	5.99e-231	-	4.1.1.35	-	M	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	3-beta hydroxysteroid dehydrogenase/isomerase family
HLFCFMOD_01255	7.18e-182	-	-	-	I	-	-	-	Acyl-ACP thioesterase
HLFCFMOD_01256	2.09e-72	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HLFCFMOD_01257	1.72e-71	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HLFCFMOD_01258	6.23e-113	-	-	-	CO	-	-	-	cell redox homeostasis
HLFCFMOD_01260	7.41e-181	-	-	-	-	-	-	-	-
HLFCFMOD_01262	0.0	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
HLFCFMOD_01264	4.02e-144	-	-	-	-	-	-	-	-
HLFCFMOD_01265	1.71e-64	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HLFCFMOD_01268	5.87e-32	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HLFCFMOD_01269	8.36e-119	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HLFCFMOD_01270	4.91e-59	cas4	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	crispr-associated protein cas4
HLFCFMOD_01271	2.92e-85	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	DEAD-like helicases superfamily
HLFCFMOD_01272	4.23e-108	-	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
HLFCFMOD_01273	5.83e-135	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
HLFCFMOD_01274	3.74e-117	csd2	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein, Csd2 family
HLFCFMOD_01275	1.13e-285	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HLFCFMOD_01276	0.0	-	1.2.1.88, 1.5.5.2	-	CE	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko03000	Proline dehydrogenase
HLFCFMOD_01278	1.01e-45	-	-	-	S	-	-	-	R3H domain
HLFCFMOD_01279	0.0	-	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Catalase
HLFCFMOD_01281	5.16e-74	-	-	-	O	-	-	-	Cytochrome C assembly protein
HLFCFMOD_01282	8.88e-268	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HLFCFMOD_01283	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HLFCFMOD_01284	4.93e-286	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HLFCFMOD_01285	1.18e-276	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
HLFCFMOD_01286	3.06e-85	-	-	-	M	ko:K03282	-	ko00000,ko02000	Large-conductance mechanosensitive channel, MscL
HLFCFMOD_01287	1.95e-312	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HLFCFMOD_01288	1.2e-105	-	-	-	S	-	-	-	ACT domain protein
HLFCFMOD_01289	9.29e-132	-	-	-	J	ko:K02356	-	ko00000,ko03012	Elongation factor P (EF-P) OB domain
HLFCFMOD_01290	2.85e-245	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
HLFCFMOD_01291	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HLFCFMOD_01292	0.0	-	-	-	L	ko:K03631	-	ko00000,ko03400	RecF/RecN/SMC N terminal domain
HLFCFMOD_01293	3.71e-190	-	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Metallo-beta-lactamase superfamily
HLFCFMOD_01294	1.45e-191	-	-	-	M	-	-	-	Glycosyl transferase WecB/TagA/CpsF family
HLFCFMOD_01295	1.76e-170	yyaQ	-	-	V	-	-	-	Protein conserved in bacteria
HLFCFMOD_01296	1.9e-90	-	-	-	-	-	-	-	-
HLFCFMOD_01299	1.35e-205	-	-	-	S	ko:K09949	-	ko00000	Protein of unknown function (DUF1009)
HLFCFMOD_01300	1.63e-298	-	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HLFCFMOD_01301	9.47e-236	-	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
HLFCFMOD_01302	6.82e-223	-	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HLFCFMOD_01303	2.52e-197	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HLFCFMOD_01304	3.51e-243	-	-	-	M	ko:K18094	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	Biotin-lipoyl like
HLFCFMOD_01305	0.0	-	-	-	V	ko:K18095	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	AcrB/AcrD/AcrF family
HLFCFMOD_01309	5.58e-289	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	NusA-like KH domain
HLFCFMOD_01310	3.73e-195	-	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
HLFCFMOD_01311	7.02e-144	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HLFCFMOD_01312	1.49e-135	-	-	-	J	-	-	-	Putative rRNA methylase
HLFCFMOD_01313	1.63e-203	-	-	-	S	-	-	-	Domain of unknown function (DUF362)
HLFCFMOD_01314	0.0	-	-	-	C	-	-	-	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein
HLFCFMOD_01315	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
HLFCFMOD_01317	0.0	-	-	-	-	-	-	-	-
HLFCFMOD_01318	1.44e-184	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HLFCFMOD_01319	6.02e-142	-	-	-	S	-	-	-	RNA recognition motif
HLFCFMOD_01320	0.0	-	-	-	M	-	-	-	Bacterial sugar transferase
HLFCFMOD_01321	8.88e-284	-	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Galactokinase galactose-binding signature
HLFCFMOD_01322	0.0	-	-	-	S	ko:K03307	-	ko00000	Sodium:solute symporter family
HLFCFMOD_01324	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
HLFCFMOD_01325	3.02e-227	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HLFCFMOD_01326	9.27e-271	-	-	-	M	-	-	-	Monogalactosyldiacylglycerol (MGDG) synthase
HLFCFMOD_01327	7.16e-174	coaX	2.7.1.33	-	K	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Type III pantothenate kinase
HLFCFMOD_01328	8.56e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
HLFCFMOD_01329	3.5e-132	-	-	-	-	-	-	-	-
HLFCFMOD_01330	5.19e-178	-	-	-	S	-	-	-	Lysin motif
HLFCFMOD_01331	5.31e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLFCFMOD_01332	4.21e-54	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HLFCFMOD_01334	1.42e-105	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HLFCFMOD_01335	1.17e-156	-	-	-	M	-	-	-	self proteolysis
HLFCFMOD_01336	1.83e-83	-	-	-	L	-	-	-	Conserved hypothetical protein 95
HLFCFMOD_01337	1.18e-309	-	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
HLFCFMOD_01338	1.98e-232	-	-	-	S	-	-	-	Aspartyl protease
HLFCFMOD_01339	3.37e-272	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLFCFMOD_01340	2.4e-160	-	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	DNA / pantothenate metabolism flavoprotein
HLFCFMOD_01341	3.38e-279	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
HLFCFMOD_01342	1.94e-104	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
HLFCFMOD_01343	2.48e-173	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HLFCFMOD_01344	0.0	-	-	-	L	-	-	-	Polyphosphate kinase 2 (PPK2)
HLFCFMOD_01345	0.0	-	-	-	S	-	-	-	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HLFCFMOD_01346	2.31e-259	-	-	-	M	-	-	-	Peptidase family M23
HLFCFMOD_01348	8.37e-126	-	4.1.1.36	-	H	ko:K01598	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Flavoprotein
HLFCFMOD_01349	1.31e-81	-	-	-	DJ	-	-	-	Addiction module toxin, RelE StbE family
HLFCFMOD_01350	2.34e-208	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HLFCFMOD_01352	1.26e-139	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
HLFCFMOD_01353	0.0	-	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HLFCFMOD_01354	4.07e-246	-	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR synthase related protein, N-terminal domain
HLFCFMOD_01355	1.84e-105	-	-	-	S	ko:K15977	-	ko00000	DoxX
HLFCFMOD_01356	1.72e-243	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HLFCFMOD_01357	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
HLFCFMOD_01358	1.84e-177	-	-	-	-	-	-	-	-
HLFCFMOD_01359	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DbpA RNA binding domain
HLFCFMOD_01360	0.0	-	-	-	P	ko:K01138	-	ko00000,ko01000	PA14 domain
HLFCFMOD_01361	6.93e-147	-	-	-	L	-	-	-	Membrane
HLFCFMOD_01364	5.84e-173	-	-	-	K	-	-	-	Transcriptional regulator
HLFCFMOD_01365	0.0	-	-	-	P	-	-	-	Dimerisation domain of Zinc Transporter
HLFCFMOD_01366	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
HLFCFMOD_01368	7.86e-242	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HLFCFMOD_01369	1.79e-201	-	-	-	S	-	-	-	SigmaW regulon antibacterial
HLFCFMOD_01371	2.02e-173	-	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiG
HLFCFMOD_01372	6.6e-294	-	-	-	E	-	-	-	Amino acid permease
HLFCFMOD_01373	5.68e-156	gph	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
HLFCFMOD_01374	6.62e-257	-	-	-	S	ko:K11744	-	ko00000	AI-2E family transporter
HLFCFMOD_01375	1.38e-313	-	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
HLFCFMOD_01376	1.32e-235	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HLFCFMOD_01377	0.0	-	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
HLFCFMOD_01378	8.55e-214	-	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HLFCFMOD_01379	5.11e-222	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
HLFCFMOD_01380	1.14e-129	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HLFCFMOD_01381	3.34e-139	-	-	-	T	-	-	-	histone H2A K63-linked ubiquitination
HLFCFMOD_01383	3.23e-253	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLFCFMOD_01384	2.84e-286	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HLFCFMOD_01385	7.7e-255	-	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HLFCFMOD_01386	3.73e-269	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HLFCFMOD_01390	4.43e-14	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
HLFCFMOD_01391	3.96e-20	-	-	-	K	-	-	-	ROK family
HLFCFMOD_01392	2.26e-10	-	-	-	L	ko:K02315	-	ko00000,ko03032	PFAM IstB domain protein ATP-binding protein
HLFCFMOD_01397	4.55e-170	-	-	-	S	-	-	-	Terminase
HLFCFMOD_01398	0.0	-	-	-	ET	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HLFCFMOD_01399	1.25e-166	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HLFCFMOD_01400	4.37e-124	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	adenylate kinase activity
HLFCFMOD_01401	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HLFCFMOD_01402	1.06e-169	-	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HLFCFMOD_01403	1.07e-192	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HLFCFMOD_01404	2.94e-155	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HLFCFMOD_01405	0.0	-	-	-	M	ko:K04744	-	ko00000,ko02000	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HLFCFMOD_01406	0.0	-	-	-	M	-	-	-	NPCBM/NEW2 domain
HLFCFMOD_01407	0.0	-	-	-	G	-	-	-	Glycogen debranching enzyme
HLFCFMOD_01408	1.83e-231	-	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
HLFCFMOD_01409	0.0	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
HLFCFMOD_01413	1.89e-100	-	-	-	MP	-	-	-	regulation of cell-substrate adhesion
HLFCFMOD_01415	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HLFCFMOD_01416	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2851)
HLFCFMOD_01417	6.39e-119	-	-	-	T	-	-	-	STAS domain
HLFCFMOD_01418	2.44e-312	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
HLFCFMOD_01419	1.26e-247	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
HLFCFMOD_01420	0.0	-	2.1.1.182	-	IJ	ko:K02528	-	ko00000,ko01000,ko03009	Ribosomal RNA adenine dimethylases
HLFCFMOD_01421	8.42e-102	-	-	-	-	-	-	-	-
HLFCFMOD_01422	9.86e-54	-	-	-	-	-	-	-	-
HLFCFMOD_01423	1.11e-121	-	-	-	-	-	-	-	-
HLFCFMOD_01424	6.81e-298	-	-	-	V	ko:K03327	-	ko00000,ko02000	drug transmembrane transporter activity
HLFCFMOD_01425	0.0	-	-	-	P	-	-	-	Cation transport protein
HLFCFMOD_01428	2.66e-148	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HLFCFMOD_01434	1.07e-264	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HLFCFMOD_01436	0.0	-	-	-	M	-	-	-	pathogenesis
HLFCFMOD_01439	1.49e-250	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HLFCFMOD_01440	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HLFCFMOD_01444	5.93e-261	-	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HLFCFMOD_01445	8.43e-155	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HLFCFMOD_01446	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, domain 2
HLFCFMOD_01447	1.24e-179	-	-	-	M	-	-	-	NLP P60 protein
HLFCFMOD_01448	6.77e-87	-	-	-	S	ko:K09940	-	ko00000	Domain of unknown function (DUF4870)
HLFCFMOD_01450	2.09e-76	-	-	-	C	ko:K04651	-	ko00000,ko03110	Hydrogenase/urease nickel incorporation, metallochaperone, hypA
HLFCFMOD_01451	3.4e-126	-	-	-	C	ko:K03605	-	ko00000,ko01000,ko01002	Hydrogenase maturation protease
HLFCFMOD_01452	6.49e-290	hyaC	-	-	C	ko:K03620	ko02020,map02020	ko00000,ko00001	Prokaryotic cytochrome b561
HLFCFMOD_01453	0.0	-	1.12.99.6	-	C	ko:K06281	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nickel-dependent hydrogenase
HLFCFMOD_01454	2.95e-299	-	1.12.99.6	-	C	ko:K06282	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	NiFe/NiFeSe hydrogenase small subunit C-terminal
HLFCFMOD_01455	0.0	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
HLFCFMOD_01457	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HLFCFMOD_01458	0.0	-	-	-	H	-	-	-	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLFCFMOD_01459	0.0	-	3.4.24.3	-	NU	ko:K01387	-	ko00000,ko01000,ko01002,ko02042	translation initiation factor activity
HLFCFMOD_01460	0.0	-	-	-	M	-	-	-	Transglycosylase
HLFCFMOD_01461	2.63e-135	-	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	Peptidyl-tRNA hydrolase
HLFCFMOD_01462	5.34e-214	-	-	-	S	-	-	-	Protein of unknown function DUF58
HLFCFMOD_01463	6.11e-97	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HLFCFMOD_01464	0.0	-	-	-	P	ko:K07239	-	ko00000	AcrB/AcrD/AcrF family
HLFCFMOD_01465	3.44e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLFCFMOD_01467	5.61e-168	-	-	-	CO	-	-	-	Protein conserved in bacteria
HLFCFMOD_01468	2.6e-231	-	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HLFCFMOD_01469	3.01e-153	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
HLFCFMOD_01470	0.0	-	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Surface antigen
HLFCFMOD_01471	2.93e-282	tig	-	-	O	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HLFCFMOD_01472	1.02e-152	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLFCFMOD_01473	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HLFCFMOD_01474	1.44e-255	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HLFCFMOD_01476	9.94e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HLFCFMOD_01478	3.61e-46	-	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecE/Sec61-gamma subunits of protein translocation complex
HLFCFMOD_01479	6.29e-135	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
HLFCFMOD_01480	2.58e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HLFCFMOD_01481	8.25e-155	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HLFCFMOD_01482	9.92e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HLFCFMOD_01483	3.69e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HLFCFMOD_01485	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLFCFMOD_01486	3.53e-226	-	-	-	-	-	-	-	-
HLFCFMOD_01487	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HLFCFMOD_01488	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RecQ zinc-binding
HLFCFMOD_01490	3.86e-304	-	-	-	M	-	-	-	Glycosyl transferases group 1
HLFCFMOD_01491	9.76e-258	-	-	-	S	-	-	-	Glycoside-hydrolase family GH114
HLFCFMOD_01492	0.0	-	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
HLFCFMOD_01493	2.86e-133	-	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	SpoU rRNA Methylase family
HLFCFMOD_01494	4.56e-206	-	3.1.1.53	-	L	ko:K03547,ko:K05970	-	ko00000,ko01000,ko03400	3'-5' exonuclease activity
HLFCFMOD_01495	4.92e-90	-	-	-	K	-	-	-	Helix-turn-helix diphteria tox regulatory element
HLFCFMOD_01496	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
HLFCFMOD_01498	2.83e-303	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
HLFCFMOD_01501	0.0	-	-	-	P	ko:K04759	-	ko00000,ko02000	Ferrous iron transport protein B C terminus
HLFCFMOD_01502	4.02e-48	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
HLFCFMOD_01503	2.48e-40	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
HLFCFMOD_01504	0.0	-	1.11.1.5	-	P	ko:K00428	-	ko00000,ko01000	Di-haem cytochrome c peroxidase
HLFCFMOD_01505	5.44e-229	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HLFCFMOD_01506	1.1e-131	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HLFCFMOD_01507	1.65e-240	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HLFCFMOD_01508	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
HLFCFMOD_01509	8.42e-285	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HLFCFMOD_01510	0.0	-	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HLFCFMOD_01511	1.37e-129	-	-	-	D	ko:K06287	-	ko00000	Maf-like protein
HLFCFMOD_01512	1.08e-289	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HLFCFMOD_01514	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HLFCFMOD_01515	0.0	-	-	-	GK	-	-	-	carbohydrate kinase activity
HLFCFMOD_01516	4.34e-202	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLFCFMOD_01517	5.49e-206	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HLFCFMOD_01518	0.0	-	-	-	I	-	-	-	Acetyltransferase (GNAT) domain
HLFCFMOD_01519	2.8e-143	-	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Cytidylate kinase
HLFCFMOD_01520	8.17e-147	-	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HLFCFMOD_01521	9.06e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HLFCFMOD_01522	3.75e-121	actI	1.5.1.36	-	S	ko:K00484	ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220	ko00000,ko00001,ko01000	FMN binding
HLFCFMOD_01523	3.86e-162	rnc	3.1.26.3	-	K	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HLFCFMOD_01524	0.0	-	-	-	P	ko:K07221	-	ko00000,ko02000	Phosphate-selective porin O and P
HLFCFMOD_01525	1.39e-257	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HLFCFMOD_01527	2.11e-272	-	-	-	S	-	-	-	regulation of ryanodine-sensitive calcium-release channel activity
HLFCFMOD_01529	3.73e-229	-	-	-	M	-	-	-	lytic endotransglycosylase activity
HLFCFMOD_01530	3.86e-18	-	-	-	-	-	-	-	-
HLFCFMOD_01531	3.77e-181	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HLFCFMOD_01532	4.83e-163	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Tetrapyrrole (Corrin/Porphyrin) Methylases
HLFCFMOD_01533	3.06e-115	-	-	-	S	-	-	-	Lipopolysaccharide-assembly
HLFCFMOD_01534	1.18e-170	-	-	-	S	ko:K05807	-	ko00000,ko02000	Outer membrane lipoprotein
HLFCFMOD_01535	4.98e-117	hisI	3.5.4.19	-	E	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-AMP cyclohydrolase
HLFCFMOD_01536	5.17e-223	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
HLFCFMOD_01537	1.35e-36	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	G/U mismatch-specific uracil-DNA glycosylase activity
HLFCFMOD_01538	3.89e-313	-	-	-	C	ko:K00185	-	ko00000	Polysulphide reductase, NrfD
HLFCFMOD_01540	6.14e-155	-	-	-	C	-	-	-	Cytochrome c
HLFCFMOD_01541	1.5e-296	-	-	-	P	-	-	-	ABC-type Zn2 transport system, periplasmic component surface adhesin
HLFCFMOD_01542	0.0	-	-	-	C	-	-	-	Cytochrome c
HLFCFMOD_01544	9.72e-61	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLFCFMOD_01545	4.59e-270	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HLFCFMOD_01546	6.74e-307	-	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
HLFCFMOD_01547	1.05e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
HLFCFMOD_01548	1.23e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HLFCFMOD_01549	0.0	-	-	-	J	-	-	-	Beta-Casp domain
HLFCFMOD_01550	2.24e-141	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HLFCFMOD_01551	1.02e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Queuosine biosynthesis protein QueC
HLFCFMOD_01552	1.78e-97	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	QueF-like protein
HLFCFMOD_01553	0.0	kefA	-	-	M	ko:K05802,ko:K22051	-	ko00000,ko02000	cellular water homeostasis
HLFCFMOD_01554	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HLFCFMOD_01555	7.46e-238	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HLFCFMOD_01556	1.18e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin resistance protein BacA
HLFCFMOD_01559	2.58e-85	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
HLFCFMOD_01560	6.59e-315	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HLFCFMOD_01561	1.65e-303	-	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HLFCFMOD_01562	1.33e-52	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLFCFMOD_01563	1.25e-155	-	-	-	JM	-	-	-	Nucleotidyl transferase
HLFCFMOD_01564	2.88e-273	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HLFCFMOD_01565	3.51e-223	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
HLFCFMOD_01567	0.0	-	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
HLFCFMOD_01568	5.87e-296	-	-	-	-	-	-	-	-
HLFCFMOD_01569	0.0	-	-	-	-	-	-	-	-
HLFCFMOD_01570	8.84e-140	mntP	-	-	P	-	-	-	manganese ion transmembrane transporter activity
HLFCFMOD_01572	4.87e-189	-	-	-	S	-	-	-	Phenazine biosynthesis-like protein
HLFCFMOD_01573	2.32e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HLFCFMOD_01574	1.48e-308	-	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, Activator interacting domain (AID)
HLFCFMOD_01575	2.23e-272	ycaD	-	-	EGP	ko:K08219	-	ko00000,ko02000	Major facilitator Superfamily
HLFCFMOD_01576	6.79e-222	-	3.4.11.10, 3.4.11.6	-	DZ	ko:K19701	-	ko00000,ko01000,ko01002	aminopeptidase activity
HLFCFMOD_01577	1.16e-287	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HLFCFMOD_01578	0.0	-	-	-	S	-	-	-	inositol 2-dehydrogenase activity
HLFCFMOD_01580	1.88e-274	-	3.6.4.13	-	L	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	helicase superfamily c-terminal domain
HLFCFMOD_01582	3.6e-145	-	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
HLFCFMOD_01583	0.0	-	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLFCFMOD_01584	6.78e-42	-	-	-	S	-	-	-	PurA ssDNA and RNA-binding protein
HLFCFMOD_01586	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	LeuA allosteric (dimerisation) domain
HLFCFMOD_01587	0.0	prlC	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
HLFCFMOD_01588	2.24e-282	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HLFCFMOD_01589	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HLFCFMOD_01590	0.0	-	-	-	MU	ko:K18139	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Outer membrane efflux protein
HLFCFMOD_01592	0.0	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HLFCFMOD_01593	1.59e-150	-	-	-	-	-	-	-	-
HLFCFMOD_01596	2.17e-101	ptsN	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HLFCFMOD_01597	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HLFCFMOD_01598	7.09e-253	-	-	-	L	-	-	-	Transposase IS200 like
HLFCFMOD_01599	0.0	-	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
HLFCFMOD_01600	1.94e-268	-	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HLFCFMOD_01601	3.89e-149	dedA	-	-	S	-	-	-	FtsZ-dependent cytokinesis
HLFCFMOD_01602	7.1e-311	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HLFCFMOD_01603	9.25e-103	-	-	-	K	-	-	-	Transcriptional regulator
HLFCFMOD_01604	1.37e-273	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLFCFMOD_01605	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	defense response to virus
HLFCFMOD_01606	7.45e-231	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	maintenance of DNA repeat elements
HLFCFMOD_01607	1.51e-73	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HLFCFMOD_01608	2.32e-259	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLFCFMOD_01610	2.33e-172	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
HLFCFMOD_01611	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Hsp90 protein
HLFCFMOD_01612	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HLFCFMOD_01613	1.92e-284	-	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
HLFCFMOD_01614	6.99e-242	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Aminoacyl tRNA synthetase class II, N-terminal domain
HLFCFMOD_01615	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	B3/4 domain
HLFCFMOD_01616	1.05e-256	-	-	-	S	-	-	-	Domain of unknown function (DUF4105)
HLFCFMOD_01617	1.66e-143	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
HLFCFMOD_01618	0.0	-	4.1.99.1	-	E	ko:K01667	ko00380,map00380	ko00000,ko00001,ko01000	Beta-eliminating lyase
HLFCFMOD_01619	6.37e-33	-	-	-	KLT	-	-	-	Tyrosine-protein kinase, subgroup, catalytic domain
HLFCFMOD_01621	2.95e-262	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLFCFMOD_01622	4.19e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HLFCFMOD_01623	1.54e-217	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Acyl transferase domain
HLFCFMOD_01625	1.34e-168	-	-	-	S	-	-	-	HAD-hyrolase-like
HLFCFMOD_01626	3.06e-286	-	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
HLFCFMOD_01627	3.63e-270	-	-	-	E	-	-	-	serine-type peptidase activity
HLFCFMOD_01628	2.03e-308	-	-	-	M	-	-	-	OmpA family
HLFCFMOD_01629	3.11e-216	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HLFCFMOD_01630	0.0	-	-	-	M	-	-	-	Peptidase M60-like family
HLFCFMOD_01631	8.03e-295	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HLFCFMOD_01632	0.0	-	-	-	KT	-	-	-	Sigma factor PP2C-like phosphatases
HLFCFMOD_01633	7.43e-164	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
HLFCFMOD_01634	9.96e-244	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HLFCFMOD_01635	4.16e-270	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	site-specific DNA-methyltransferase (adenine-specific) activity
HLFCFMOD_01636	3.24e-94	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HLFCFMOD_01637	0.0	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HLFCFMOD_01639	0.0	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HLFCFMOD_01641	1.04e-109	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HLFCFMOD_01642	8.76e-126	-	-	-	-	-	-	-	-
HLFCFMOD_01643	0.0	-	-	-	U	ko:K03321	-	ko00000,ko02000	Sulfate permease family
HLFCFMOD_01644	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase C-terminal
HLFCFMOD_01645	2.05e-162	-	-	-	S	-	-	-	SWIM zinc finger
HLFCFMOD_01646	0.0	-	-	-	-	-	-	-	-
HLFCFMOD_01647	2.46e-307	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLFCFMOD_01648	4.2e-204	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HLFCFMOD_01649	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HLFCFMOD_01650	1.9e-257	-	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HLFCFMOD_01651	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
HLFCFMOD_01652	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HLFCFMOD_01653	6.96e-305	-	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	tRNA (Uracil-5-)-methyltransferase
HLFCFMOD_01656	0.0	-	-	-	-	-	-	-	-
HLFCFMOD_01657	3.33e-285	pgk	2.7.2.3	-	G	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HLFCFMOD_01658	3.15e-237	-	-	-	-	-	-	-	-
HLFCFMOD_01659	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	myo-inosose-2 dehydratase activity
HLFCFMOD_01660	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
HLFCFMOD_01661	0.0	-	-	-	L	-	-	-	TRCF
HLFCFMOD_01662	1.55e-294	-	-	-	-	-	-	-	-
HLFCFMOD_01663	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HLFCFMOD_01664	3e-254	-	-	-	S	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HLFCFMOD_01666	5.56e-214	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	PHP domain
HLFCFMOD_01667	1.4e-259	-	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphate acetyl/butaryl transferase
HLFCFMOD_01668	4.05e-242	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HLFCFMOD_01669	7.42e-75	-	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HLFCFMOD_01673	3.85e-210	-	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
HLFCFMOD_01674	8.42e-05	-	-	-	-	-	-	-	-
HLFCFMOD_01675	0.0	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HLFCFMOD_01676	1.32e-313	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
HLFCFMOD_01677	6.95e-264	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
HLFCFMOD_01679	8.62e-102	-	-	-	-	-	-	-	-
HLFCFMOD_01680	8.08e-236	gpsA	1.1.1.94	-	C	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HLFCFMOD_01681	4.34e-152	-	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Glycerol-3-phosphate acyltransferase
HLFCFMOD_01682	2.5e-188	pppL	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	protein serine/threonine phosphatase activity
HLFCFMOD_01683	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
HLFCFMOD_01684	0.0	-	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HLFCFMOD_01685	1.32e-101	manC	-	-	S	-	-	-	Cupin domain
HLFCFMOD_01686	3.2e-70	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HLFCFMOD_01687	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
HLFCFMOD_01688	2.58e-178	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HLFCFMOD_01701	3.89e-74	-	-	-	KT	-	-	-	Peptidase S24-like
HLFCFMOD_01703	8.3e-12	-	-	-	-	-	-	-	-
HLFCFMOD_01705	8.26e-07	-	-	-	L	-	-	-	Excalibur calcium-binding domain
HLFCFMOD_01707	5.68e-30	-	-	-	D	-	-	-	Phage minor structural protein
HLFCFMOD_01717	1.2e-167	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HLFCFMOD_01718	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
HLFCFMOD_01719	2.54e-208	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HLFCFMOD_01720	1.42e-271	-	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
HLFCFMOD_01721	4.4e-138	-	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HLFCFMOD_01722	1.23e-187	-	5.2.1.8	-	O	ko:K03773	-	ko00000,ko01000,ko03110	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
HLFCFMOD_01723	0.0	-	-	-	U	-	-	-	Passenger-associated-transport-repeat
HLFCFMOD_01724	2e-84	-	-	-	-	-	-	-	-
HLFCFMOD_01725	8.92e-111	-	-	-	U	-	-	-	response to pH
HLFCFMOD_01726	9.39e-183	-	-	-	H	-	-	-	ThiF family
HLFCFMOD_01727	6.8e-224	-	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
HLFCFMOD_01728	4.7e-193	-	-	-	-	-	-	-	-
HLFCFMOD_01729	1.31e-290	-	4.2.1.129, 5.4.99.17	-	I	ko:K06045	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
HLFCFMOD_01730	1.06e-109	-	-	-	S	ko:K15977	-	ko00000	DoxX
HLFCFMOD_01731	1.34e-201	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase, N-terminal
HLFCFMOD_01732	1.73e-307	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HLFCFMOD_01733	1.71e-179	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLFCFMOD_01734	0.0	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HLFCFMOD_01735	0.0	-	-	-	K	-	-	-	Transcription elongation factor, N-terminal
HLFCFMOD_01736	1.89e-166	-	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	SAICAR synthetase
HLFCFMOD_01737	5.55e-116	-	-	-	-	-	-	-	-
HLFCFMOD_01738	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
HLFCFMOD_01739	1.3e-177	-	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
HLFCFMOD_01741	2.24e-263	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HLFCFMOD_01742	1.68e-114	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
HLFCFMOD_01743	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	ATPases associated with a variety of cellular activities
HLFCFMOD_01745	5.42e-30	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HLFCFMOD_01746	1.44e-110	-	-	-	S	-	-	-	Putative zinc- or iron-chelating domain
HLFCFMOD_01747	6.21e-304	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HLFCFMOD_01748	2.9e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Semialdehyde dehydrogenase, NAD binding domain
HLFCFMOD_01750	3.15e-05	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLFCFMOD_01757	9.32e-131	-	-	-	S	-	-	-	Glycosyl hydrolase 108
HLFCFMOD_01759	1.35e-18	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
HLFCFMOD_01764	6.77e-127	-	-	-	-	-	-	-	-
HLFCFMOD_01765	0.0	-	-	-	M	-	-	-	Sulfatase
HLFCFMOD_01766	1.4e-287	-	4.1.99.19	-	H	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Biotin and Thiamin Synthesis associated domain
HLFCFMOD_01767	1.39e-206	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
HLFCFMOD_01768	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HLFCFMOD_01769	3.35e-77	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	COG0732 Restriction endonuclease S subunits
HLFCFMOD_01770	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HLFCFMOD_01772	6.81e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3847)
HLFCFMOD_01773	0.0	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Dehydratase family
HLFCFMOD_01774	2.81e-167	-	-	-	T	ko:K07657	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HLFCFMOD_01775	4.97e-290	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HLFCFMOD_01776	2.09e-10	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
HLFCFMOD_01777	3.88e-207	hisG	2.4.2.17	-	E	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HLFCFMOD_01778	2.04e-314	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
HLFCFMOD_01780	3.63e-135	rbr	-	-	C	-	-	-	Rubrerythrin
HLFCFMOD_01781	5.35e-145	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HLFCFMOD_01783	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk_gamma
HLFCFMOD_01784	5.68e-180	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	polysaccharide export
HLFCFMOD_01785	0.0	gumC	-	-	DM	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	PFAM lipopolysaccharide biosynthesis protein
HLFCFMOD_01786	1.11e-163	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	protein tyrosine phosphatase activity
HLFCFMOD_01787	2.3e-174	-	-	-	M	-	-	-	Bacterial sugar transferase
HLFCFMOD_01788	1.63e-187	wbyL	-	GT2	M	ko:K13002	-	ko00000,ko01000,ko01003,ko01005	transferase activity, transferring glycosyl groups
HLFCFMOD_01789	4.23e-292	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HLFCFMOD_01790	8.15e-285	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HLFCFMOD_01791	9.62e-292	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HLFCFMOD_01794	2.14e-148	-	-	-	S	-	-	-	3D domain
HLFCFMOD_01795	2.15e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HLFCFMOD_01796	9.91e-171	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HLFCFMOD_01797	3.19e-111	aglS	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
HLFCFMOD_01798	5.28e-100	exbD2	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
HLFCFMOD_01799	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HLFCFMOD_01800	1.28e-193	-	-	-	-	-	-	-	-
HLFCFMOD_01801	7.71e-278	-	-	-	K	-	-	-	sequence-specific DNA binding
HLFCFMOD_01802	0.0	-	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	Ribonuclease E/G family
HLFCFMOD_01803	5.06e-236	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Actin
HLFCFMOD_01804	0.0	lacZ_17	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HLFCFMOD_01807	1.96e-121	ngr	-	-	C	-	-	-	Rubrerythrin
HLFCFMOD_01808	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1705)
HLFCFMOD_01809	0.0	-	-	-	M	-	-	-	Glycosyl Hydrolase Family 88
HLFCFMOD_01810	0.0	-	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
HLFCFMOD_01811	3.8e-43	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	CTP reductase activity
HLFCFMOD_01812	1.52e-188	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
HLFCFMOD_01813	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
HLFCFMOD_01814	0.0	-	-	-	T	-	-	-	Histidine kinase
HLFCFMOD_01815	1.33e-110	-	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HLFCFMOD_01816	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HLFCFMOD_01817	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HLFCFMOD_01818	7.36e-55	himA	-	-	L	ko:K03530,ko:K04764,ko:K05788	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
HLFCFMOD_01820	0.0	-	-	-	G	-	-	-	Polysaccharide deacetylase
HLFCFMOD_01821	0.0	-	-	-	P	-	-	-	Putative Na+/H+ antiporter
HLFCFMOD_01822	1.25e-140	-	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Lumazine binding domain
HLFCFMOD_01823	2.42e-203	-	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
HLFCFMOD_01824	0.0	pmp21	-	-	T	-	-	-	pathogenesis
HLFCFMOD_01825	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HLFCFMOD_01827	0.0	-	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Uncharacterized protein family UPF0004
HLFCFMOD_01828	0.0	-	-	-	-	ko:K07403	-	ko00000	-
HLFCFMOD_01829	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HLFCFMOD_01830	0.0	-	-	-	CO	-	-	-	Thioredoxin-like
HLFCFMOD_01835	2.36e-116	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HLFCFMOD_01836	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
HLFCFMOD_01837	1.22e-246	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HLFCFMOD_01838	2.73e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HLFCFMOD_01839	4.98e-117	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HLFCFMOD_01840	1.16e-78	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
HLFCFMOD_01841	3.6e-243	-	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HLFCFMOD_01842	4.45e-128	aroK	2.7.1.71	-	E	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HLFCFMOD_01843	9.56e-51	-	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S16
HLFCFMOD_01845	5.39e-13	-	-	-	E	-	-	-	LysE type translocator
HLFCFMOD_01846	1.31e-214	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HLFCFMOD_01847	1.26e-183	-	-	-	DTZ	-	-	-	EF-hand, calcium binding motif
HLFCFMOD_01848	5.64e-66	-	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
HLFCFMOD_01849	1.39e-282	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HLFCFMOD_01850	1.22e-150	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Putative methyltransferase
HLFCFMOD_01851	3.55e-173	-	-	-	F	-	-	-	NUDIX domain
HLFCFMOD_01852	3.84e-118	-	-	-	D	-	-	-	Tetratricopeptide repeat
HLFCFMOD_01853	2.18e-195	-	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HLFCFMOD_01854	0.0	-	-	-	-	-	-	-	-
HLFCFMOD_01855	1.38e-223	-	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
HLFCFMOD_01856	6.68e-314	-	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HLFCFMOD_01857	1.21e-153	-	4.1.3.38	-	E	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	branched-chain-amino-acid transaminase activity
HLFCFMOD_01858	7.63e-249	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HLFCFMOD_01859	2.09e-150	-	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HLFCFMOD_01860	4.49e-269	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HLFCFMOD_01862	2.5e-170	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
HLFCFMOD_01863	7.35e-119	-	-	-	T	ko:K07005	-	ko00000	pyridoxamine 5'-phosphate
HLFCFMOD_01864	1.51e-173	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Glutamine amidotransferase class-I
HLFCFMOD_01866	4.96e-113	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Cys-tRNA(Pro) hydrolase activity
HLFCFMOD_01867	0.0	mmyX	5.3.1.12	-	F	ko:K01812,ko:K07149,ko:K16139	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score
HLFCFMOD_01868	2.07e-95	-	-	-	-	-	-	-	-
HLFCFMOD_01869	1.28e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4236)
HLFCFMOD_01871	2.53e-146	-	-	-	Q	-	-	-	PA14
HLFCFMOD_01872	3.85e-194	-	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	CDP-alcohol phosphatidyltransferase
HLFCFMOD_01873	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HLFCFMOD_01874	5.59e-227	-	-	-	M	ko:K01993	-	ko00000	HlyD family secretion protein
HLFCFMOD_01875	0.0	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLFCFMOD_01876	1.03e-243	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HLFCFMOD_01877	1.07e-246	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HLFCFMOD_01880	1.11e-299	nupG	-	-	G	ko:K03289,ko:K03301,ko:K08218,ko:K11537	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HLFCFMOD_01881	4.16e-259	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLFCFMOD_01882	9.82e-110	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07305,ko:K12267	-	ko00000,ko01000	peptide-methionine (R)-S-oxide reductase activity
HLFCFMOD_01883	1.12e-305	-	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLFCFMOD_01884	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HLFCFMOD_01885	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HLFCFMOD_01886	7.28e-132	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HLFCFMOD_01887	3.88e-263	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
HLFCFMOD_01888	4.33e-234	-	2.7.11.1	-	T	ko:K08884,ko:K12132,ko:K20333	ko02024,map02024	ko00000,ko00001,ko01000,ko01001	PFAM Formylglycine-generating sulfatase enzyme
HLFCFMOD_01890	2.06e-196	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HLFCFMOD_01891	9.18e-137	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
HLFCFMOD_01892	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HLFCFMOD_01893	6.35e-277	-	-	-	C	-	-	-	Aldo/keto reductase family
HLFCFMOD_01894	6.71e-90	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HLFCFMOD_01895	6.99e-260	-	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HLFCFMOD_01897	6.53e-296	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HLFCFMOD_01898	7.45e-296	-	-	-	MU	ko:K15725	-	ko00000,ko02000	efflux transmembrane transporter activity
HLFCFMOD_01900	1.83e-205	-	-	-	G	ko:K06867,ko:K07001	-	ko00000	response to abiotic stimulus
HLFCFMOD_01901	0.0	-	-	-	E	-	-	-	PFAM major facilitator superfamily MFS_1
HLFCFMOD_01904	1.36e-214	-	-	-	KQ	-	-	-	Hypothetical methyltransferase
HLFCFMOD_01905	2.18e-290	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HLFCFMOD_01906	0.0	ahcY	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HLFCFMOD_01907	3.5e-249	rgpB	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HLFCFMOD_01908	5.14e-246	-	-	-	-	-	-	-	-
HLFCFMOD_01909	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HLFCFMOD_01911	0.0	secD	-	-	U	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HLFCFMOD_01912	9.72e-227	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HLFCFMOD_01913	1.1e-173	-	-	-	T	-	-	-	Outer membrane lipoprotein-sorting protein
HLFCFMOD_01914	3.17e-166	-	-	-	S	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
HLFCFMOD_01915	1.88e-250	-	-	-	-	-	-	-	-
HLFCFMOD_01917	5.46e-170	-	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HLFCFMOD_01918	1.79e-216	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HLFCFMOD_01921	7.58e-209	-	-	-	J	ko:K01894	-	ko00000,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), catalytic domain
HLFCFMOD_01922	0.0	-	-	-	P	-	-	-	Citrate transporter
HLFCFMOD_01923	4.39e-145	-	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
HLFCFMOD_01924	2.58e-196	-	-	-	S	-	-	-	Domain of unknown function (DUF1732)
HLFCFMOD_01926	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
HLFCFMOD_01927	5.29e-161	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HLFCFMOD_01928	3.89e-267	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLFCFMOD_01929	0.0	-	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
HLFCFMOD_01930	7.45e-301	-	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
HLFCFMOD_01932	0.0	-	-	-	P	-	-	-	Sulfatase
HLFCFMOD_01936	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HLFCFMOD_01937	1.73e-221	-	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Glutaminase
HLFCFMOD_01938	2.43e-95	-	-	-	K	-	-	-	-acetyltransferase
HLFCFMOD_01939	5.82e-308	-	-	-	E	ko:K03310	-	ko00000	Sodium:alanine symporter family
HLFCFMOD_01941	3.95e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HLFCFMOD_01942	1.16e-213	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HLFCFMOD_01945	7.33e-42	-	-	-	S	-	-	-	Oxygen tolerance
HLFCFMOD_01946	1.36e-204	yeaE	-	-	S	-	-	-	aldo-keto reductase (NADP) activity
HLFCFMOD_01947	0.0	-	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Anticodon binding domain
HLFCFMOD_01948	8.72e-155	-	-	-	S	-	-	-	DUF218 domain
HLFCFMOD_01949	1.93e-209	-	-	-	S	-	-	-	CAAX protease self-immunity
HLFCFMOD_01950	3.2e-286	-	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
HLFCFMOD_01951	8.26e-106	-	-	-	K	-	-	-	Lrp/AsnC ligand binding domain
HLFCFMOD_01952	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HLFCFMOD_01953	8.46e-84	-	-	-	P	ko:K06195	-	ko00000	ApaG domain
HLFCFMOD_01954	7.47e-203	-	-	-	-	-	-	-	-
HLFCFMOD_01955	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HLFCFMOD_01956	0.0	-	-	-	C	-	-	-	cytochrome C peroxidase
HLFCFMOD_01957	0.0	-	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HLFCFMOD_01958	1.99e-19	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	COG0010 Arginase agmatinase formimionoglutamate hydrolase arginase family
HLFCFMOD_01959	5.05e-297	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32
HLFCFMOD_01960	1.37e-149	-	-	-	C	-	-	-	lactate oxidation
HLFCFMOD_01961	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA Topoisomerase IV
HLFCFMOD_01962	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLFCFMOD_01963	1.23e-255	-	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Iron-sulfur cluster assembly protein
HLFCFMOD_01964	0.0	-	-	-	V	ko:K03327	-	ko00000,ko02000	MatE
HLFCFMOD_01967	0.0	-	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	HMGL-like
HLFCFMOD_01968	0.0	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phospholipase D. Active site motifs.
HLFCFMOD_01969	5.77e-208	-	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Thymidylate synthase
HLFCFMOD_01970	5.02e-115	-	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Dihydrofolate reductase
HLFCFMOD_01971	0.0	-	-	-	V	-	-	-	AcrB/AcrD/AcrF family
HLFCFMOD_01972	4.2e-264	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Biotin-lipoyl like
HLFCFMOD_01973	1.69e-107	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HLFCFMOD_01976	0.0	-	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HLFCFMOD_01977	6.26e-218	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HLFCFMOD_01978	9.37e-256	-	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	endonuclease III
HLFCFMOD_01979	1.22e-143	aat	2.3.2.6	-	O	ko:K00684	-	ko00000,ko01000	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HLFCFMOD_01980	0.0	-	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Pyruvate phosphate dikinase, PEP/pyruvate binding domain
HLFCFMOD_01981	4.29e-235	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglucose isomerase
HLFCFMOD_01982	2.38e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HLFCFMOD_01983	2.25e-105	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HLFCFMOD_01984	1.66e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HLFCFMOD_01985	5.36e-138	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLFCFMOD_01986	1.53e-47	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S L24/mitochondrial 39S L24
HLFCFMOD_01987	4.2e-208	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLFCFMOD_01988	1.77e-124	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
HLFCFMOD_01989	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HLFCFMOD_01990	0.0	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 Helicase protein
HLFCFMOD_01991	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HLFCFMOD_01994	1.85e-142	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HLFCFMOD_01995	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
HLFCFMOD_01996	2.27e-245	-	-	-	-	-	-	-	-
HLFCFMOD_01997	1.06e-208	-	-	-	-	-	-	-	-
HLFCFMOD_01998	0.0	-	-	-	NU	-	-	-	Type IV pilus assembly protein PilM;
HLFCFMOD_01999	2.8e-169	-	-	-	-	-	-	-	-
HLFCFMOD_02000	5.43e-255	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HLFCFMOD_02001	7.19e-261	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HLFCFMOD_02002	4.87e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF3313)
HLFCFMOD_02003	9.67e-283	-	2.3.1.40, 6.2.1.20	-	IQ	ko:K05939	ko00071,ko00564,map00071,map00564	ko00000,ko00001,ko01000	AMP-binding enzyme
HLFCFMOD_02004	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLFCFMOD_02005	6.39e-71	-	-	-	-	-	-	-	-
HLFCFMOD_02008	5.49e-206	-	-	-	S	ko:K03453	-	ko00000	Bile acid
HLFCFMOD_02009	4.43e-291	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HLFCFMOD_02011	5.74e-211	ybfH	-	-	EG	-	-	-	spore germination
HLFCFMOD_02012	2.27e-75	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
HLFCFMOD_02013	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
HLFCFMOD_02014	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HLFCFMOD_02015	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HLFCFMOD_02016	9.83e-235	-	-	-	CO	-	-	-	Thioredoxin-like
HLFCFMOD_02018	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLFCFMOD_02019	6.21e-39	-	-	-	-	-	-	-	-
HLFCFMOD_02021	0.0	-	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	B12 binding domain
HLFCFMOD_02022	1.66e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HLFCFMOD_02023	2.34e-108	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HLFCFMOD_02025	0.0	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HLFCFMOD_02026	2.52e-281	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HLFCFMOD_02028	1.12e-116	agmK	1.8.1.8	-	O	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	belongs to the thioredoxin family
HLFCFMOD_02029	1.92e-179	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
HLFCFMOD_02030	2.58e-56	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HLFCFMOD_02031	4.88e-169	-	4.3.99.3	-	O	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HLFCFMOD_02032	6.62e-182	-	2.7.13.3	-	Q	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Transposase
HLFCFMOD_02033	0.0	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HLFCFMOD_02034	2.2e-313	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
HLFCFMOD_02035	2.58e-252	-	-	-	E	-	-	-	Aminotransferase class-V
HLFCFMOD_02036	5.45e-234	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HLFCFMOD_02037	9.2e-214	-	-	-	K	-	-	-	LysR substrate binding domain
HLFCFMOD_02040	1.1e-22	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HLFCFMOD_02041	2.57e-170	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HLFCFMOD_02042	1.58e-307	-	-	-	C	-	-	-	Sulfatase-modifying factor enzyme 1
HLFCFMOD_02043	1.43e-11	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLFCFMOD_02045	1.15e-05	-	-	-	-	-	-	-	-
HLFCFMOD_02047	7.45e-49	XK27_09985	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HLFCFMOD_02048	3.37e-193	-	-	-	S	ko:K07051	-	ko00000	TatD related DNase
HLFCFMOD_02049	8.94e-56	-	-	-	-	-	-	-	-
HLFCFMOD_02050	4.83e-163	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	-
HLFCFMOD_02051	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
HLFCFMOD_02052	1.29e-187	-	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	2Fe-2S iron-sulfur cluster binding domain
HLFCFMOD_02053	9.49e-262	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
HLFCFMOD_02054	1.39e-221	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HLFCFMOD_02056	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
HLFCFMOD_02057	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
HLFCFMOD_02061	3.6e-145	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HLFCFMOD_02062	1.48e-141	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HLFCFMOD_02064	3.56e-131	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HLFCFMOD_02065	1.31e-219	prs	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLFCFMOD_02066	1.97e-228	-	-	-	C	-	-	-	Transmembrane exosortase (Exosortase_EpsH)
HLFCFMOD_02067	1.76e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF3485)
HLFCFMOD_02068	5.71e-165	pks6	-	-	Q	-	-	-	amino acid activation for nonribosomal peptide biosynthetic process
HLFCFMOD_02069	6.29e-151	-	-	-	-	-	-	-	-
HLFCFMOD_02070	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HLFCFMOD_02071	1.41e-283	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HLFCFMOD_02072	1.21e-241	-	-	-	E	ko:K07588	-	ko00000,ko01000	ArgK protein
HLFCFMOD_02073	2.21e-113	-	-	-	F	ko:K08311	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	NUDIX domain
HLFCFMOD_02074	0.0	sepA	-	-	Q	-	-	-	COG2015, Alkyl sulfatase and related hydrolases
HLFCFMOD_02075	2.83e-121	-	-	-	-	-	-	-	-
HLFCFMOD_02076	1.71e-110	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HLFCFMOD_02077	1.22e-290	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
HLFCFMOD_02078	8.17e-159	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HLFCFMOD_02079	1.53e-241	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase
HLFCFMOD_02080	5.53e-285	-	5.4.99.22	-	M	ko:K06178	-	ko00000,ko01000,ko03009	translation initiation factor activity
HLFCFMOD_02081	2.29e-136	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HLFCFMOD_02082	7.4e-93	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
HLFCFMOD_02083	8.02e-130	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLFCFMOD_02084	8.59e-293	-	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 57
HLFCFMOD_02085	5.2e-315	-	-	-	G	-	-	-	Glycosyl transferase 4-like domain
HLFCFMOD_02086	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 31
HLFCFMOD_02088	6.04e-197	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Peptidase S24-like
HLFCFMOD_02089	1.18e-227	-	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HLFCFMOD_02090	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HLFCFMOD_02091	2.96e-242	-	3.1.3.18	-	F	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HLFCFMOD_02092	1.1e-174	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HLFCFMOD_02093	1.2e-262	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HLFCFMOD_02094	1.72e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLFCFMOD_02095	3.65e-60	-	-	-	S	ko:K09131	-	ko00000	DUF167
HLFCFMOD_02096	4.5e-176	-	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HLFCFMOD_02097	0.0	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	Helix-hairpin-helix class 2 (Pol1 family) motifs
HLFCFMOD_02098	1.12e-248	-	-	-	M	-	-	-	HlyD family secretion protein
HLFCFMOD_02099	2.52e-102	MA20_05485	-	-	S	-	-	-	Putative bacterial sensory transduction regulator
HLFCFMOD_02100	0.0	-	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
HLFCFMOD_02101	6.21e-304	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HLFCFMOD_02102	4.22e-267	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
HLFCFMOD_02103	4.07e-217	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HLFCFMOD_02104	1.11e-261	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HLFCFMOD_02105	7e-268	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Aminomethyltransferase folate-binding domain
HLFCFMOD_02106	6.67e-86	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HLFCFMOD_02107	0.0	gcvP	1.4.4.2	-	E	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HLFCFMOD_02108	1.26e-10	-	-	-	D	-	-	-	nuclear chromosome segregation
HLFCFMOD_02109	2.94e-131	-	-	-	-	-	-	-	-
HLFCFMOD_02110	1.59e-243	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
HLFCFMOD_02113	8.93e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyrroline-5-carboxylate reductase dimerisation
HLFCFMOD_02114	8.1e-160	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HLFCFMOD_02115	5.51e-211	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
HLFCFMOD_02116	6.59e-227	-	-	-	S	-	-	-	Protein conserved in bacteria
HLFCFMOD_02117	1.56e-60	-	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S6
HLFCFMOD_02118	8.87e-212	-	1.1.1.262	-	H	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal phosphate biosynthetic protein PdxA
HLFCFMOD_02121	9.66e-224	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
HLFCFMOD_02122	1.1e-254	-	2.7.1.11, 2.7.1.90	-	G	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Phosphofructokinase
HLFCFMOD_02123	1.38e-219	-	-	-	L	-	-	-	Membrane
HLFCFMOD_02124	6.18e-173	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	transporter
HLFCFMOD_02125	8.72e-235	-	-	-	CO	-	-	-	Protein of unknown function, DUF255
HLFCFMOD_02126	6.73e-47	-	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	tRNA synthetases class I (W and Y)
HLFCFMOD_02127	9.48e-237	-	-	-	S	ko:K14347	-	ko00000,ko02000,ko04147	SBF-like CPA transporter family (DUF4137)
HLFCFMOD_02130	0.0	-	-	-	S	-	-	-	Large extracellular alpha-helical protein
HLFCFMOD_02131	0.0	-	-	-	M	-	-	-	Aerotolerance regulator N-terminal
HLFCFMOD_02132	1.57e-223	-	-	-	S	-	-	-	Peptidase family M28
HLFCFMOD_02135	1.06e-182	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
HLFCFMOD_02136	0.0	-	-	-	KLT	-	-	-	Sulfatase-modifying factor enzyme 1
HLFCFMOD_02137	3.77e-289	kbl	2.3.1.29	-	E	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HLFCFMOD_02138	7.13e-101	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HLFCFMOD_02139	2.49e-183	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HLFCFMOD_02140	0.0	-	-	-	N	-	-	-	ABC-type uncharacterized transport system
HLFCFMOD_02141	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
HLFCFMOD_02142	1.57e-190	-	-	-	S	-	-	-	NIF3 (NGG1p interacting factor 3)
HLFCFMOD_02143	3.72e-237	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HLFCFMOD_02144	3.98e-277	-	4.2.1.51, 5.4.99.5	-	E	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
HLFCFMOD_02146	2.04e-158	-	-	-	S	-	-	-	Peptidase family M50
HLFCFMOD_02147	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Prolyl-tRNA synthetase, C-terminal
HLFCFMOD_02150	2.73e-88	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HLFCFMOD_02152	0.0	-	-	-	E	-	-	-	Peptidase dimerisation domain
HLFCFMOD_02153	8.83e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HLFCFMOD_02154	2.01e-139	-	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
HLFCFMOD_02155	0.0	-	-	-	S	-	-	-	50S ribosome-binding GTPase
HLFCFMOD_02156	1.02e-163	-	-	-	S	ko:K06997	-	ko00000	Alanine racemase, N-terminal domain
HLFCFMOD_02157	2.2e-134	-	-	-	K	ko:K07735	-	ko00000,ko03000	Uncharacterized ACR, COG1678
HLFCFMOD_02158	4.92e-121	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HLFCFMOD_02159	5.44e-292	-	-	-	S	ko:K07126,ko:K13582	ko04112,map04112	ko00000,ko00001	beta-lactamase activity
HLFCFMOD_02161	5.88e-279	-	6.2.1.26	-	IQ	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	AMP-binding enzyme
HLFCFMOD_02162	1.27e-70	-	-	-	K	-	-	-	ribonuclease III activity
HLFCFMOD_02163	1.55e-164	-	-	-	-	-	-	-	-
HLFCFMOD_02164	2.1e-140	nuoC	1.6.5.3	-	C	ko:K00332	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HLFCFMOD_02165	6.52e-139	nuoB	1.6.5.3	-	C	ko:K00331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HLFCFMOD_02169	2.7e-147	-	-	-	IQ	-	-	-	RmlD substrate binding domain
HLFCFMOD_02170	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GcpE protein
HLFCFMOD_02171	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
HLFCFMOD_02172	2.15e-198	-	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HLFCFMOD_02173	4.03e-120	-	-	-	-	-	-	-	-
HLFCFMOD_02174	4.68e-192	-	-	-	KT	-	-	-	Peptidase S24-like
HLFCFMOD_02176	2.29e-141	-	-	-	M	-	-	-	polygalacturonase activity
HLFCFMOD_02177	5.92e-303	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HLFCFMOD_02178	1.71e-239	-	1.2.7.3	-	-	ko:K00176,ko:K07138	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	-
HLFCFMOD_02180	0.0	-	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
HLFCFMOD_02181	6.2e-203	-	-	-	-	-	-	-	-
HLFCFMOD_02182	4.04e-240	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HLFCFMOD_02183	1.61e-176	-	-	-	O	-	-	-	Trypsin
HLFCFMOD_02186	8.22e-290	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HLFCFMOD_02187	4.39e-180	-	-	-	-	-	-	-	-
HLFCFMOD_02188	0.0	-	-	-	S	-	-	-	von Willebrand factor type A domain
HLFCFMOD_02189	0.0	-	-	-	S	-	-	-	Aerotolerance regulator N-terminal
HLFCFMOD_02190	5.75e-208	-	-	-	S	-	-	-	Protein of unknown function DUF58
HLFCFMOD_02193	4.07e-52	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
HLFCFMOD_02199	1.22e-111	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
HLFCFMOD_02200	0.0	-	3.2.1.52	GH20	G	ko:K01207,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko01501,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map01501,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HLFCFMOD_02201	7.6e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLFCFMOD_02202	9.74e-227	-	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate synthetase A protein
HLFCFMOD_02203	2.9e-254	-	-	-	S	-	-	-	Putative S-adenosyl-L-methionine-dependent methyltransferase
HLFCFMOD_02205	3.49e-216	-	3.5.1.53	-	K	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HLFCFMOD_02207	2.36e-273	-	-	-	E	-	-	-	Alcohol dehydrogenase GroES-like domain
HLFCFMOD_02208	1.43e-309	-	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Seryl-tRNA synthetase N-terminal domain
HLFCFMOD_02209	4.38e-211	-	-	-	S	-	-	-	Protein of unknown function DUF58
HLFCFMOD_02210	2.48e-228	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HLFCFMOD_02211	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HLFCFMOD_02212	5.79e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLFCFMOD_02214	2.63e-10	-	-	-	-	-	-	-	-
HLFCFMOD_02216	1.8e-124	nuoI	1.6.5.3	-	C	ko:K00338	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HLFCFMOD_02217	1.04e-309	nuoH	1.6.5.3	-	C	ko:K00337	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HLFCFMOD_02218	0.0	-	1.6.5.3	-	C	ko:K00336	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
HLFCFMOD_02219	1.38e-168	-	1.6.5.3	-	C	ko:K00335	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
HLFCFMOD_02221	0.0	-	-	-	S	-	-	-	Sodium:neurotransmitter symporter family
HLFCFMOD_02222	3.6e-152	-	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HLFCFMOD_02224	2.59e-125	-	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Phosphoribosyl transferase domain
HLFCFMOD_02226	1.59e-142	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HLFCFMOD_02228	3.15e-123	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HLFCFMOD_02229	0.0	-	-	-	-	-	-	-	-
HLFCFMOD_02230	1.78e-241	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HLFCFMOD_02233	0.0	-	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	DNA Topoisomerase IV
HLFCFMOD_02234	1.83e-74	-	-	-	-	-	-	-	-
HLFCFMOD_02235	0.000969	-	-	-	-	-	-	-	-
HLFCFMOD_02236	0.0	-	-	-	G	-	-	-	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain
HLFCFMOD_02238	1.53e-107	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HLFCFMOD_02240	0.0	-	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HLFCFMOD_02241	1.29e-151	hprK	-	-	T	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
HLFCFMOD_02242	8.72e-53	-	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
HLFCFMOD_02243	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLFCFMOD_02247	2.31e-25	-	-	-	U	-	-	-	Passenger-associated-transport-repeat
HLFCFMOD_02249	4.85e-146	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HLFCFMOD_02250	3.42e-135	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K00788,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HLFCFMOD_02251	2.33e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HLFCFMOD_02253	2.88e-142	-	1.6.5.3	-	C	ko:K00334	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Thioredoxin-like [2Fe-2S] ferredoxin
HLFCFMOD_02254	1.79e-306	nuoD	1.6.5.3	-	C	ko:K00333	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HLFCFMOD_02255	0.0	-	2.6.1.66	-	E	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HLFCFMOD_02258	8.51e-42	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HLFCFMOD_02261	8.51e-108	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HLFCFMOD_02265	1.24e-200	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
HLFCFMOD_02266	2.47e-273	-	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
HLFCFMOD_02269	8.34e-124	-	-	-	S	-	-	-	Protein of unknown function (DUF1194)
HLFCFMOD_02270	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HLFCFMOD_02272	1.73e-249	-	-	-	-	-	-	-	-
HLFCFMOD_02273	1.14e-126	-	-	-	M	-	-	-	Polymer-forming cytoskeletal