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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NHLBIJJH_00001	2.75e-289	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
NHLBIJJH_00002	0.0	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	thiolester hydrolase activity
NHLBIJJH_00003	7.26e-285	-	-	-	IQ	-	-	-	Beta-ketoacyl synthase, C-terminal domain
NHLBIJJH_00004	3.3e-261	-	2.3.1.47	-	H	ko:K00652	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
NHLBIJJH_00008	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NHLBIJJH_00009	4.26e-310	-	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
NHLBIJJH_00010	1.19e-174	hypB	-	-	KO	ko:K04652	-	ko00000,ko03110	CobW/HypB/UreG, nucleotide-binding domain
NHLBIJJH_00011	0.0	-	-	-	O	ko:K04656	-	ko00000	HypF finger
NHLBIJJH_00012	2.74e-50	-	-	-	O	ko:K04653	-	ko00000	HupF/HypC family
NHLBIJJH_00013	2.61e-260	-	-	-	O	ko:K04654	-	ko00000	Hydrogenase formation hypA family
NHLBIJJH_00014	4.02e-238	-	-	-	O	ko:K04655	-	ko00000	AIR synthase related protein, N-terminal domain
NHLBIJJH_00015	1.33e-278	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
NHLBIJJH_00016	0.0	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
NHLBIJJH_00017	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	MreB/Mbl protein
NHLBIJJH_00018	2.2e-61	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NHLBIJJH_00019	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NHLBIJJH_00020	7.54e-99	-	-	-	S	-	-	-	peptidase
NHLBIJJH_00021	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
NHLBIJJH_00025	1.62e-297	-	-	-	-	-	-	-	-
NHLBIJJH_00026	0.0	-	-	-	D	-	-	-	Chain length determinant protein
NHLBIJJH_00027	2.63e-142	-	-	-	M	-	-	-	Polysaccharide biosynthesis/export protein
NHLBIJJH_00029	1.09e-148	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NHLBIJJH_00030	1.67e-249	-	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
NHLBIJJH_00031	2.74e-284	pgk	2.7.2.3	-	G	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
NHLBIJJH_00032	1.1e-237	-	-	-	-	-	-	-	-
NHLBIJJH_00033	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	myo-inosose-2 dehydratase activity
NHLBIJJH_00034	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
NHLBIJJH_00035	0.0	-	-	-	L	-	-	-	TRCF
NHLBIJJH_00036	3.12e-294	-	-	-	-	-	-	-	-
NHLBIJJH_00037	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
NHLBIJJH_00038	7.36e-255	-	-	-	S	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
NHLBIJJH_00040	5.56e-214	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	PHP domain
NHLBIJJH_00041	5.69e-259	-	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphate acetyl/butaryl transferase
NHLBIJJH_00042	2.73e-240	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NHLBIJJH_00043	2.59e-75	-	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NHLBIJJH_00047	1.33e-100	-	-	-	MP	-	-	-	regulation of cell-substrate adhesion
NHLBIJJH_00051	0.0	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
NHLBIJJH_00052	1.83e-231	-	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
NHLBIJJH_00053	0.0	-	-	-	G	-	-	-	Glycogen debranching enzyme
NHLBIJJH_00054	0.0	-	-	-	M	-	-	-	NPCBM/NEW2 domain
NHLBIJJH_00055	0.0	-	-	-	M	ko:K04744	-	ko00000,ko02000	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NHLBIJJH_00056	1.29e-153	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
NHLBIJJH_00057	2.94e-190	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
NHLBIJJH_00058	3.17e-171	-	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
NHLBIJJH_00059	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
NHLBIJJH_00060	4.37e-124	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	adenylate kinase activity
NHLBIJJH_00061	5.08e-166	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NHLBIJJH_00062	0.0	-	-	-	ET	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NHLBIJJH_00064	1.18e-252	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Semialdehyde dehydrogenase, NAD binding domain
NHLBIJJH_00065	2.26e-306	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NHLBIJJH_00066	1.44e-110	-	-	-	S	-	-	-	Putative zinc- or iron-chelating domain
NHLBIJJH_00067	7.7e-31	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
NHLBIJJH_00070	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	ATPases associated with a variety of cellular activities
NHLBIJJH_00071	1.02e-149	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
NHLBIJJH_00072	1.14e-126	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
NHLBIJJH_00073	5.8e-248	-	-	-	-	-	-	-	-
NHLBIJJH_00075	8.71e-174	-	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
NHLBIJJH_00076	3.01e-59	-	-	-	S	ko:K09131	-	ko00000	DUF167
NHLBIJJH_00077	3.47e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NHLBIJJH_00078	9.85e-262	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NHLBIJJH_00079	4.47e-174	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NHLBIJJH_00080	2.96e-242	-	3.1.3.18	-	F	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
NHLBIJJH_00081	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
NHLBIJJH_00082	1.02e-228	-	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
NHLBIJJH_00083	0.0	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Peptidase S24-like
NHLBIJJH_00084	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
NHLBIJJH_00085	6.29e-151	-	-	-	-	-	-	-	-
NHLBIJJH_00086	2.07e-167	pks6	-	-	Q	-	-	-	amino acid activation for nonribosomal peptide biosynthetic process
NHLBIJJH_00087	4.32e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF3485)
NHLBIJJH_00088	5.89e-230	-	-	-	C	-	-	-	Transmembrane exosortase (Exosortase_EpsH)
NHLBIJJH_00089	4.58e-220	prs	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHLBIJJH_00090	3.56e-131	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NHLBIJJH_00092	1.48e-141	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
NHLBIJJH_00093	1.31e-147	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NHLBIJJH_00094	1.56e-60	-	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S6
NHLBIJJH_00095	2.09e-210	-	1.1.1.262	-	H	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal phosphate biosynthetic protein PdxA
NHLBIJJH_00098	3.37e-224	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
NHLBIJJH_00099	1.56e-254	-	2.7.1.11, 2.7.1.90	-	G	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Phosphofructokinase
NHLBIJJH_00100	1.18e-220	-	-	-	L	-	-	-	Membrane
NHLBIJJH_00101	6.18e-173	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	transporter
NHLBIJJH_00102	1.51e-235	-	-	-	CO	-	-	-	Protein of unknown function, DUF255
NHLBIJJH_00105	0.0	-	2.6.1.66	-	E	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
NHLBIJJH_00106	2.47e-194	-	-	-	S	-	-	-	Domain of unknown function (DUF1732)
NHLBIJJH_00107	1.08e-145	-	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
NHLBIJJH_00108	0.0	-	-	-	P	-	-	-	Citrate transporter
NHLBIJJH_00109	7.58e-209	-	-	-	J	ko:K01894	-	ko00000,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), catalytic domain
NHLBIJJH_00112	1.79e-216	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
NHLBIJJH_00113	1.56e-169	-	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
NHLBIJJH_00115	8.93e-249	-	-	-	-	-	-	-	-
NHLBIJJH_00116	1.51e-164	-	-	-	S	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
NHLBIJJH_00117	4.48e-173	-	-	-	T	-	-	-	Outer membrane lipoprotein-sorting protein
NHLBIJJH_00118	9.72e-227	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
NHLBIJJH_00119	0.0	secD	-	-	U	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NHLBIJJH_00121	1.09e-276	-	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
NHLBIJJH_00122	2.38e-258	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
NHLBIJJH_00123	2.95e-262	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHLBIJJH_00124	4.19e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NHLBIJJH_00125	4.4e-217	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Acyl transferase domain
NHLBIJJH_00127	1.29e-166	-	-	-	S	-	-	-	HAD-hyrolase-like
NHLBIJJH_00128	3.06e-286	-	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
NHLBIJJH_00129	1.04e-269	-	-	-	E	-	-	-	serine-type peptidase activity
NHLBIJJH_00130	1.13e-300	-	-	-	M	-	-	-	OmpA family
NHLBIJJH_00131	1.17e-211	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NHLBIJJH_00132	0.0	-	-	-	M	-	-	-	Peptidase M60-like family
NHLBIJJH_00133	9.77e-296	-	-	-	EGP	-	-	-	Major facilitator Superfamily
NHLBIJJH_00134	0.0	-	-	-	KT	-	-	-	Sigma factor PP2C-like phosphatases
NHLBIJJH_00135	6.91e-165	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
NHLBIJJH_00136	2.01e-243	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
NHLBIJJH_00137	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
NHLBIJJH_00138	1.83e-128	-	-	-	S	-	-	-	Domain of unknown function (DUF4391)
NHLBIJJH_00139	0.0	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	PFAM DNA methylase N-4 N-6 domain protein
NHLBIJJH_00140	0.0	res	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
NHLBIJJH_00141	7e-158	-	-	-	NU	ko:K02457,ko:K08084	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	protein transport across the cell outer membrane
NHLBIJJH_00142	9.06e-189	-	-	-	-	-	-	-	-
NHLBIJJH_00143	2.55e-247	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
NHLBIJJH_00144	6.92e-183	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
NHLBIJJH_00145	4.06e-244	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
NHLBIJJH_00146	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
NHLBIJJH_00150	0.0	-	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
NHLBIJJH_00151	0.0	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NHLBIJJH_00152	9.26e-175	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
NHLBIJJH_00153	4.18e-155	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
NHLBIJJH_00154	3.6e-287	-	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NHLBIJJH_00155	9.44e-189	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NHLBIJJH_00157	0.0	-	-	-	T	-	-	-	pathogenesis
NHLBIJJH_00158	1.35e-92	-	-	-	O	-	-	-	response to oxidative stress
NHLBIJJH_00159	7.92e-294	-	2.3.1.31	-	E	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko01000	alpha/beta hydrolase fold
NHLBIJJH_00160	2.53e-62	-	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
NHLBIJJH_00161	0.0	-	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Glycosyltransferase family 9 (heptosyltransferase)
NHLBIJJH_00162	1.11e-190	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
NHLBIJJH_00163	0.0	-	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
NHLBIJJH_00164	8.08e-189	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
NHLBIJJH_00165	1.29e-186	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
NHLBIJJH_00166	0.0	-	-	-	EG	-	-	-	BNR repeat-like domain
NHLBIJJH_00167	0.0	legA	3.5.1.2	-	G	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	response to abiotic stimulus
NHLBIJJH_00168	3.96e-197	supH	-	-	Q	-	-	-	phosphatase activity
NHLBIJJH_00170	5.49e-85	nuoA	1.6.5.3	-	C	ko:K00330	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NHLBIJJH_00171	7.13e-276	-	-	-	G	-	-	-	Major Facilitator Superfamily
NHLBIJJH_00175	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NHLBIJJH_00176	2.91e-38	-	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
NHLBIJJH_00177	5.25e-79	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NHLBIJJH_00178	0.0	-	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Peptidase family M50
NHLBIJJH_00181	0.0	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
NHLBIJJH_00182	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
NHLBIJJH_00183	2.07e-209	MA20_36650	-	-	EG	-	-	-	spore germination
NHLBIJJH_00184	0.0	-	-	-	S	-	-	-	Alpha-2-macroglobulin family
NHLBIJJH_00185	3.91e-289	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
NHLBIJJH_00187	2.89e-123	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
NHLBIJJH_00190	1.79e-213	-	-	-	-	-	-	-	-
NHLBIJJH_00191	3.97e-152	-	-	-	O	-	-	-	Glycoprotease family
NHLBIJJH_00192	4.99e-273	-	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
NHLBIJJH_00194	3.86e-112	-	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NHLBIJJH_00195	4.12e-139	-	-	-	L	-	-	-	RNase_H superfamily
NHLBIJJH_00197	6.68e-103	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NHLBIJJH_00198	1.5e-44	-	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	RNA polymerase activity
NHLBIJJH_00199	3.51e-136	-	5.4.99.20	-	J	ko:K06181	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
NHLBIJJH_00200	2.66e-216	-	-	-	-	-	-	-	-
NHLBIJJH_00201	1.3e-104	-	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	NDK
NHLBIJJH_00202	5.54e-207	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NHLBIJJH_00203	3.38e-224	-	-	-	M	-	-	-	Glycosyl transferase family 2
NHLBIJJH_00205	7.26e-285	-	-	-	NU	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
NHLBIJJH_00206	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein E, N-terminal domain
NHLBIJJH_00207	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
NHLBIJJH_00208	5.14e-245	-	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHLBIJJH_00209	2.83e-110	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
NHLBIJJH_00210	3.86e-281	-	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
NHLBIJJH_00211	0.0	murJ	-	-	S	ko:K03980	-	ko00000,ko01011,ko02000	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NHLBIJJH_00212	1.26e-271	-	-	-	IM	-	-	-	Cytidylyltransferase-like
NHLBIJJH_00213	1.74e-157	-	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Iron/manganese superoxide dismutases, alpha-hairpin domain
NHLBIJJH_00214	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase-like 10
NHLBIJJH_00215	5.6e-171	-	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
NHLBIJJH_00216	2.4e-191	-	-	-	L	ko:K06864	-	ko00000	tRNA processing
NHLBIJJH_00217	2.03e-292	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NHLBIJJH_00218	1.07e-238	-	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Polyprenyl synthetase
NHLBIJJH_00219	0.0	-	-	-	E	ko:K03305	-	ko00000	POT family
NHLBIJJH_00220	0.0	-	5.2.1.8	-	O	ko:K03770	-	ko00000,ko01000,ko03110	PPIC-type PPIASE domain
NHLBIJJH_00221	2.39e-126	-	-	-	S	-	-	-	Pfam:DUF59
NHLBIJJH_00222	7.43e-107	-	-	-	-	-	-	-	-
NHLBIJJH_00224	3.12e-219	-	-	-	E	-	-	-	Domain of unknown function (DUF3472)
NHLBIJJH_00225	0.0	nuoN	1.6.5.3	-	C	ko:K00343	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NHLBIJJH_00226	0.0	-	1.6.5.3	-	C	ko:K00342	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Proton-conducting membrane transporter
NHLBIJJH_00227	0.0	-	1.6.5.3	-	CP	ko:K00341	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
NHLBIJJH_00228	6.01e-61	nuoK	1.6.5.3	-	C	ko:K00340	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NHLBIJJH_00229	2.18e-156	-	1.6.5.3	-	C	ko:K00339	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone/plastoquinone oxidoreductase chain 6
NHLBIJJH_00230	1.8e-124	nuoI	1.6.5.3	-	C	ko:K00338	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NHLBIJJH_00231	1.04e-309	nuoH	1.6.5.3	-	C	ko:K00337	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NHLBIJJH_00232	0.0	-	1.6.5.3	-	C	ko:K00336	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
NHLBIJJH_00233	0.0	-	1.6.5.3	-	C	ko:K00335	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
NHLBIJJH_00234	2.88e-142	-	1.6.5.3	-	C	ko:K00334	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Thioredoxin-like [2Fe-2S] ferredoxin
NHLBIJJH_00235	4.39e-307	nuoD	1.6.5.3	-	C	ko:K00333	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NHLBIJJH_00237	0.0	-	-	-	G	-	-	-	Polysaccharide deacetylase
NHLBIJJH_00238	0.0	-	-	-	P	-	-	-	Putative Na+/H+ antiporter
NHLBIJJH_00239	1.03e-139	-	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Lumazine binding domain
NHLBIJJH_00240	2.42e-203	-	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
NHLBIJJH_00241	0.0	pmp21	-	-	T	-	-	-	pathogenesis
NHLBIJJH_00242	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
NHLBIJJH_00244	0.0	-	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Uncharacterized protein family UPF0004
NHLBIJJH_00245	0.0	-	-	-	-	ko:K07403	-	ko00000	-
NHLBIJJH_00246	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NHLBIJJH_00247	0.0	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NHLBIJJH_00248	3.72e-187	-	3.4.13.22	-	M	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-ala-D-ala dipeptidase
NHLBIJJH_00251	0.0	-	-	-	E	-	-	-	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NHLBIJJH_00252	0.0	-	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	tail specific protease
NHLBIJJH_00253	4.66e-215	-	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
NHLBIJJH_00254	0.0	-	3.6.4.13	-	L	ko:K03579	-	ko00000,ko01000	ATP-dependent helicase C-terminal
NHLBIJJH_00255	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
NHLBIJJH_00256	5.86e-312	-	-	-	O	-	-	-	peroxiredoxin activity
NHLBIJJH_00257	0.0	-	2.7.7.19	-	J	ko:K00970	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Poly A polymerase head domain
NHLBIJJH_00258	0.0	-	-	-	G	-	-	-	Alpha amylase, catalytic domain
NHLBIJJH_00259	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
NHLBIJJH_00260	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_00261	7.21e-183	-	-	-	S	ko:K09778	-	ko00000	Domain of unknown function (DUF374)
NHLBIJJH_00262	7.21e-203	folD	1.5.1.5, 3.5.4.9	-	H	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NHLBIJJH_00263	8.33e-182	-	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NHLBIJJH_00264	1.58e-203	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
NHLBIJJH_00265	2.42e-284	-	-	-	E	-	-	-	Transglutaminase-like superfamily
NHLBIJJH_00266	1.23e-260	-	-	-	J	ko:K05541	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHLBIJJH_00267	1.87e-289	-	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	LytB protein
NHLBIJJH_00269	2.34e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S20
NHLBIJJH_00270	1.16e-141	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NHLBIJJH_00271	0.0	-	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
NHLBIJJH_00272	2.2e-221	-	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Phosphatidylserine decarboxylase
NHLBIJJH_00273	1.1e-151	-	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3 epimerase family
NHLBIJJH_00274	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Leucyl-tRNA synthetase, Domain 2
NHLBIJJH_00275	0.0	-	-	-	P	-	-	-	Sulfatase
NHLBIJJH_00277	8.7e-300	-	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
NHLBIJJH_00278	0.0	-	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
NHLBIJJH_00279	3.33e-268	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NHLBIJJH_00280	2.12e-161	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
NHLBIJJH_00281	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
NHLBIJJH_00282	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
NHLBIJJH_00283	0.0	rarA	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
NHLBIJJH_00284	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
NHLBIJJH_00286	9.49e-302	-	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
NHLBIJJH_00287	5.22e-216	-	-	-	M	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
NHLBIJJH_00288	3.61e-268	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
NHLBIJJH_00291	4.46e-127	cobU	2.7.1.156, 2.7.7.62, 6.3.5.10	-	H	ko:K02231,ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cobinamide kinase activity
NHLBIJJH_00292	2.35e-207	-	-	-	G	-	-	-	myo-inosose-2 dehydratase activity
NHLBIJJH_00293	1.62e-172	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NHLBIJJH_00294	4.02e-239	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NHLBIJJH_00295	2.15e-235	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NHLBIJJH_00296	0.0	cobQ	-	-	H	-	-	-	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
NHLBIJJH_00297	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
NHLBIJJH_00298	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NHLBIJJH_00299	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
NHLBIJJH_00300	6.65e-160	-	-	-	M	ko:K16079	-	ko00000,ko02000	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NHLBIJJH_00301	1.89e-316	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
NHLBIJJH_00302	0.0	-	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NHLBIJJH_00303	4.55e-95	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
NHLBIJJH_00304	4.66e-59	-	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	nucleotidyltransferase activity
NHLBIJJH_00305	1.34e-225	-	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
NHLBIJJH_00306	0.0	-	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoglutarate dehydrogenase C-terminal
NHLBIJJH_00307	4.23e-245	-	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit II
NHLBIJJH_00308	0.0	-	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
NHLBIJJH_00309	6.38e-112	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NHLBIJJH_00310	1.92e-106	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
NHLBIJJH_00311	0.0	-	-	-	T	-	-	-	Chase2 domain
NHLBIJJH_00312	1.51e-235	-	2.7.1.221	-	S	ko:K07102	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Phosphotransferase enzyme family
NHLBIJJH_00313	1.25e-307	-	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NHLBIJJH_00314	4.98e-92	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NHLBIJJH_00316	1.23e-112	-	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Ferritin-like domain
NHLBIJJH_00317	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_00318	2.59e-102	-	-	-	J	-	-	-	YjgF/chorismate_mutase-like, putative endoribonuclease
NHLBIJJH_00320	2.98e-71	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NHLBIJJH_00324	2.78e-06	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
NHLBIJJH_00327	1.07e-37	-	-	-	-	-	-	-	-
NHLBIJJH_00328	7.73e-134	-	-	-	V	-	-	-	Protein of unknown function DUF262
NHLBIJJH_00329	3.15e-123	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
NHLBIJJH_00330	3.6e-73	-	-	-	KT	-	-	-	Peptidase S24-like
NHLBIJJH_00337	5.12e-50	-	-	-	S	-	-	-	AAA domain
NHLBIJJH_00346	3.12e-135	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
NHLBIJJH_00347	1.76e-175	-	-	-	S	-	-	-	peptidoglycan biosynthetic process
NHLBIJJH_00348	1.3e-206	-	1.4.1.16	-	S	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
NHLBIJJH_00350	0.000103	-	-	-	S	-	-	-	Entericidin EcnA/B family
NHLBIJJH_00351	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NHLBIJJH_00352	4.27e-133	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	reductase
NHLBIJJH_00353	7.12e-152	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NHLBIJJH_00354	7.99e-78	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NHLBIJJH_00355	2.31e-232	-	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	prohibitin homologues
NHLBIJJH_00356	2.13e-118	-	-	-	-	-	-	-	-
NHLBIJJH_00357	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
NHLBIJJH_00358	2.45e-50	-	-	-	-	-	-	-	-
NHLBIJJH_00359	6.35e-298	lpxK	2.7.1.130	-	M	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
NHLBIJJH_00360	4.56e-139	-	-	-	S	ko:K07164	-	ko00000	C4-type zinc ribbon domain
NHLBIJJH_00362	3.18e-264	-	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
NHLBIJJH_00363	3.68e-75	-	-	-	-	-	-	-	-
NHLBIJJH_00364	4.15e-191	-	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	MazG nucleotide pyrophosphohydrolase domain
NHLBIJJH_00365	2.92e-70	-	-	-	-	-	-	-	-
NHLBIJJH_00366	5.9e-181	-	-	-	S	-	-	-	competence protein
NHLBIJJH_00367	2.03e-101	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
NHLBIJJH_00371	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Sulfatase
NHLBIJJH_00372	2.63e-143	-	-	-	-	-	-	-	-
NHLBIJJH_00373	1.29e-164	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
NHLBIJJH_00374	4.82e-178	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHLBIJJH_00375	1.11e-299	-	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	16S rRNA methyltransferase RsmB/F
NHLBIJJH_00376	1.18e-114	-	3.1.6.8	-	P	ko:K01134	ko00600,ko04142,map00600,map04142	ko00000,ko00001,ko01000	COG3119 Arylsulfatase A
NHLBIJJH_00377	2.9e-316	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Arginosuccinate synthase
NHLBIJJH_00379	2.79e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHLBIJJH_00380	8.43e-59	-	-	-	S	-	-	-	Zinc ribbon domain
NHLBIJJH_00381	4.77e-310	-	-	-	S	-	-	-	PFAM CBS domain containing protein
NHLBIJJH_00382	2.51e-151	-	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
NHLBIJJH_00383	9.76e-82	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
NHLBIJJH_00385	4.79e-177	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
NHLBIJJH_00386	1.38e-228	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
NHLBIJJH_00387	1.39e-157	-	-	-	S	-	-	-	3D domain
NHLBIJJH_00388	2.15e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHLBIJJH_00389	9.91e-171	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
NHLBIJJH_00390	3.19e-111	aglS	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
NHLBIJJH_00391	5.28e-100	exbD2	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
NHLBIJJH_00392	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
NHLBIJJH_00393	1.1e-194	-	-	-	-	-	-	-	-
NHLBIJJH_00394	8.99e-277	-	-	-	K	-	-	-	sequence-specific DNA binding
NHLBIJJH_00395	0.0	-	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	Ribonuclease E/G family
NHLBIJJH_00396	5.06e-236	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Actin
NHLBIJJH_00397	0.0	lacZ_17	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
NHLBIJJH_00399	2.24e-263	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
NHLBIJJH_00401	3.71e-177	-	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
NHLBIJJH_00402	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
NHLBIJJH_00403	5.55e-116	-	-	-	-	-	-	-	-
NHLBIJJH_00404	1.89e-166	-	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	SAICAR synthetase
NHLBIJJH_00405	0.0	-	-	-	K	-	-	-	Transcription elongation factor, N-terminal
NHLBIJJH_00406	0.0	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NHLBIJJH_00408	7.4e-181	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHLBIJJH_00409	1.73e-307	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NHLBIJJH_00410	1.34e-201	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase, N-terminal
NHLBIJJH_00411	1.06e-109	-	-	-	S	ko:K15977	-	ko00000	DoxX
NHLBIJJH_00412	2.76e-292	-	4.2.1.129, 5.4.99.17	-	I	ko:K06045	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
NHLBIJJH_00413	4.7e-193	-	-	-	-	-	-	-	-
NHLBIJJH_00414	1.95e-223	-	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
NHLBIJJH_00415	9.39e-183	-	-	-	H	-	-	-	ThiF family
NHLBIJJH_00416	8.92e-111	-	-	-	U	-	-	-	response to pH
NHLBIJJH_00417	1.01e-223	-	-	-	-	-	-	-	-
NHLBIJJH_00418	4.09e-218	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NHLBIJJH_00420	4.75e-59	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NHLBIJJH_00421	2.32e-70	-	-	-	S	-	-	-	Haem-degrading
NHLBIJJH_00423	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
NHLBIJJH_00424	1.72e-268	-	-	-	S	-	-	-	COGs COG4299 conserved
NHLBIJJH_00425	3.16e-127	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NHLBIJJH_00426	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein dimerisation domain
NHLBIJJH_00427	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_00428	1.04e-217	-	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	ATP synthase A chain
NHLBIJJH_00429	1.65e-11	-	-	-	S	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	PFAM H transporting two-sector ATPase C subunit
NHLBIJJH_00430	4.38e-78	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase B/B' CF(0)
NHLBIJJH_00431	1.85e-85	-	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase delta (OSCP) subunit
NHLBIJJH_00432	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NHLBIJJH_00433	4.5e-201	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NHLBIJJH_00434	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NHLBIJJH_00435	1.24e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NHLBIJJH_00436	1.38e-139	-	-	-	-	-	-	-	-
NHLBIJJH_00437	8.17e-124	sprT	-	-	K	-	-	-	SprT-like family
NHLBIJJH_00438	4.27e-275	-	-	-	S	-	-	-	COGs COG4299 conserved
NHLBIJJH_00439	4.44e-284	-	2.6.1.59	-	M	ko:K02805	-	ko00000,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
NHLBIJJH_00440	4.94e-114	flmH	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NHLBIJJH_00441	3.11e-219	-	-	-	M	-	-	-	Glycosyl transferase family 2
NHLBIJJH_00442	1.08e-73	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
NHLBIJJH_00443	1.93e-77	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
NHLBIJJH_00446	0.0	-	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
NHLBIJJH_00447	7.19e-234	-	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Biotin and Thiamin Synthesis associated domain
NHLBIJJH_00448	0.0	-	-	-	P	-	-	-	Sulfatase
NHLBIJJH_00449	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
NHLBIJJH_00450	2.04e-293	-	-	-	O	ko:K09015	-	ko00000	Uncharacterized protein family (UPF0051)
NHLBIJJH_00451	0.0	-	-	-	O	ko:K09014	-	ko00000	Uncharacterized protein family (UPF0051)
NHLBIJJH_00452	1.02e-178	-	-	-	O	ko:K09013	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
NHLBIJJH_00453	2.36e-100	-	-	-	P	ko:K09825	-	ko00000,ko03000	Ferric uptake regulator family
NHLBIJJH_00454	2.14e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
NHLBIJJH_00455	1.93e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal prokaryotic L21 protein
NHLBIJJH_00456	3.9e-105	-	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
NHLBIJJH_00457	3.73e-200	-	-	-	S	ko:K06889	-	ko00000	alpha beta
NHLBIJJH_00459	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
NHLBIJJH_00460	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_00461	3.66e-225	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
NHLBIJJH_00463	1.94e-175	-	-	-	-	-	-	-	-
NHLBIJJH_00464	3.35e-131	-	-	-	L	-	-	-	Conserved hypothetical protein 95
NHLBIJJH_00465	3.37e-309	-	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
NHLBIJJH_00466	7.42e-230	-	-	-	S	-	-	-	Aspartyl protease
NHLBIJJH_00467	1.67e-272	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NHLBIJJH_00468	8.3e-158	-	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	DNA / pantothenate metabolism flavoprotein
NHLBIJJH_00469	9.7e-279	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
NHLBIJJH_00470	3.35e-105	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
NHLBIJJH_00471	2.48e-173	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
NHLBIJJH_00472	0.0	-	-	-	L	-	-	-	Polyphosphate kinase 2 (PPK2)
NHLBIJJH_00473	0.0	-	-	-	S	-	-	-	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
NHLBIJJH_00474	9.81e-261	-	-	-	M	-	-	-	Peptidase family M23
NHLBIJJH_00476	8.37e-126	-	4.1.1.36	-	H	ko:K01598	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Flavoprotein
NHLBIJJH_00477	1.31e-81	-	-	-	DJ	-	-	-	Addiction module toxin, RelE StbE family
NHLBIJJH_00478	6.71e-208	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
NHLBIJJH_00480	4.21e-138	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
NHLBIJJH_00481	0.0	-	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NHLBIJJH_00482	6.75e-245	-	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR synthase related protein, N-terminal domain
NHLBIJJH_00483	1.84e-105	-	-	-	S	ko:K15977	-	ko00000	DoxX
NHLBIJJH_00484	1.72e-243	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NHLBIJJH_00485	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
NHLBIJJH_00486	1.02e-174	-	-	-	-	-	-	-	-
NHLBIJJH_00487	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DbpA RNA binding domain
NHLBIJJH_00488	0.0	-	-	-	P	ko:K01138	-	ko00000,ko01000	PA14 domain
NHLBIJJH_00489	2.07e-148	-	-	-	L	-	-	-	Membrane
NHLBIJJH_00491	0.0	gcvP	1.4.4.2	-	E	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NHLBIJJH_00492	6.67e-86	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
NHLBIJJH_00493	7e-268	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Aminomethyltransferase folate-binding domain
NHLBIJJH_00494	5.5e-262	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NHLBIJJH_00495	4.25e-219	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
NHLBIJJH_00496	5.75e-265	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
NHLBIJJH_00497	8.54e-269	-	-	-	M	-	-	-	Glycosyl transferase 4-like
NHLBIJJH_00498	1.96e-223	-	-	-	M	ko:K07276	-	ko00000	Mitochondrial fission ELM1
NHLBIJJH_00499	3.9e-270	-	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
NHLBIJJH_00500	1.11e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NHLBIJJH_00501	2.11e-121	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NHLBIJJH_00502	4.36e-142	-	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S4/S9 N-terminal domain
NHLBIJJH_00503	3.44e-192	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
NHLBIJJH_00507	4.37e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NHLBIJJH_00508	0.0	-	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
NHLBIJJH_00509	5.92e-289	-	3.5.1.42	-	S	ko:K03742	ko00760,map00760	ko00000,ko00001,ko01000	Competence-damaged protein
NHLBIJJH_00510	6.87e-153	-	-	-	O	-	-	-	methyltransferase activity
NHLBIJJH_00511	7.92e-183	-	-	-	U	ko:K20276	ko02024,map02024	ko00000,ko00001	domain, Protein
NHLBIJJH_00512	0.0	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
NHLBIJJH_00513	2.62e-262	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Elongator protein 3, MiaB family, Radical SAM
NHLBIJJH_00514	1.1e-197	-	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SRP54-type protein, GTPase domain
NHLBIJJH_00515	8.13e-206	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NHLBIJJH_00516	7.32e-105	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NHLBIJJH_00517	5.79e-289	-	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase II
NHLBIJJH_00518	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), anti-codon binding domain
NHLBIJJH_00519	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_00520	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
NHLBIJJH_00521	3.42e-259	-	-	-	S	-	-	-	ankyrin repeats
NHLBIJJH_00522	2.58e-312	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
NHLBIJJH_00523	1.06e-44	-	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S21
NHLBIJJH_00524	0.0	-	2.7.1.167, 2.7.7.70	-	M	ko:K03272	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	pfkB family carbohydrate kinase
NHLBIJJH_00525	8.25e-131	-	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
NHLBIJJH_00526	6.23e-118	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Polynucleotide kinase 3 phosphatase
NHLBIJJH_00527	9.97e-222	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
NHLBIJJH_00529	3.01e-251	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
NHLBIJJH_00530	1.63e-189	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHLBIJJH_00531	1.4e-195	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLBIJJH_00532	3.28e-187	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NHLBIJJH_00533	1.48e-120	-	-	-	M	ko:K06142	-	ko00000	Outer membrane protein (OmpH-like)
NHLBIJJH_00534	8.39e-197	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NHLBIJJH_00535	6.38e-151	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHLBIJJH_00537	1.04e-142	-	-	-	-	-	-	-	-
NHLBIJJH_00538	1.35e-200	-	-	-	S	-	-	-	DisA bacterial checkpoint controller nucleotide-binding
NHLBIJJH_00540	1.7e-153	-	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	AAA domain
NHLBIJJH_00541	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
NHLBIJJH_00542	0.0	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
NHLBIJJH_00543	2.19e-182	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NHLBIJJH_00545	1.33e-174	-	-	-	NU	-	-	-	Prepilin-type N-terminal cleavage methylation domain
NHLBIJJH_00546	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	PFAM coagulation factor 5 8 type domain protein
NHLBIJJH_00547	9.86e-168	-	-	-	M	-	-	-	Peptidase family M23
NHLBIJJH_00548	1.48e-144	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHLBIJJH_00549	7.54e-201	-	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NHLBIJJH_00552	0.0	-	-	-	S	-	-	-	Terminase
NHLBIJJH_00553	1.7e-178	-	-	-	D	ko:K19234,ko:K19236	ko01503,map01503	ko00000,ko00001,ko01002,ko01011	ErfK ybiS ycfS ynhG family protein
NHLBIJJH_00554	4.89e-153	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NHLBIJJH_00555	3.01e-49	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal_S15
NHLBIJJH_00556	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NHLBIJJH_00557	9.05e-313	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	PFAM CBS domain containing protein
NHLBIJJH_00558	1.88e-308	-	-	-	S	-	-	-	PFAM CBS domain containing protein
NHLBIJJH_00559	0.0	-	-	-	C	-	-	-	Cytochrome c554 and c-prime
NHLBIJJH_00560	1.63e-164	-	-	-	CO	-	-	-	Thioredoxin-like
NHLBIJJH_00561	1.1e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHLBIJJH_00562	2.72e-155	-	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase
NHLBIJJH_00563	1.22e-237	pyrD	1.3.5.2	-	F	ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
NHLBIJJH_00564	0.0	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase alpha chain like domain
NHLBIJJH_00565	1.01e-139	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NHLBIJJH_00566	0.0	-	4.1.1.15	-	E	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase conserved domain
NHLBIJJH_00567	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_00569	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
NHLBIJJH_00571	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
NHLBIJJH_00572	0.0	-	-	-	KT	ko:K02584	ko02020,map02020	ko00000,ko00001,ko03000	Bacterial regulatory protein, Fis family
NHLBIJJH_00573	9.68e-221	-	2.5.1.21	-	I	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01006	Squalene/phytoene synthase
NHLBIJJH_00574	0.0	-	-	-	S	-	-	-	Fungal chitosanase of glycosyl hydrolase group 75
NHLBIJJH_00575	3.01e-190	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
NHLBIJJH_00576	8.38e-98	-	-	-	-	-	-	-	-
NHLBIJJH_00577	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
NHLBIJJH_00580	9.85e-147	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
NHLBIJJH_00584	7.55e-302	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	efflux transmembrane transporter activity
NHLBIJJH_00587	4.36e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Enoyl-CoA hydratase/isomerase
NHLBIJJH_00588	1.29e-257	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
NHLBIJJH_00590	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHLBIJJH_00591	4.69e-79	rsfS	-	-	S	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NHLBIJJH_00592	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NHLBIJJH_00593	9.22e-141	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease
NHLBIJJH_00594	1.63e-175	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NHLBIJJH_00595	0.0	-	-	-	CO	-	-	-	Disulphide bond corrector protein DsbC
NHLBIJJH_00596	1.86e-94	-	-	-	O	-	-	-	OsmC-like protein
NHLBIJJH_00598	3.42e-111	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
NHLBIJJH_00599	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
NHLBIJJH_00601	2.07e-204	-	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
NHLBIJJH_00602	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
NHLBIJJH_00603	4.97e-168	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHLBIJJH_00604	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NHLBIJJH_00606	6.2e-155	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
NHLBIJJH_00608	1.24e-230	-	-	-	EP	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
NHLBIJJH_00609	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
NHLBIJJH_00610	9.67e-251	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
NHLBIJJH_00611	1.1e-125	-	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Recombination protein O N terminal
NHLBIJJH_00612	3.99e-183	-	-	-	S	-	-	-	Tetratricopeptide repeat
NHLBIJJH_00613	0.0	dxs	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NHLBIJJH_00614	5.12e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
NHLBIJJH_00615	0.0	-	-	-	O	-	-	-	C-terminal four TMM region of protein-O-mannosyltransferase
NHLBIJJH_00616	0.0	-	-	-	T	-	-	-	Bacterial regulatory protein, Fis family
NHLBIJJH_00617	1.82e-274	-	-	-	T	-	-	-	PAS domain
NHLBIJJH_00618	3.37e-97	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase superfamily
NHLBIJJH_00619	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	BPG-independent PGAM N-terminus (iPGM_N)
NHLBIJJH_00620	4.16e-85	-	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S12/S23
NHLBIJJH_00621	2.91e-104	-	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S7p/S5e
NHLBIJJH_00622	0.0	-	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NHLBIJJH_00623	3.67e-65	-	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S10p/S20e
NHLBIJJH_00624	3.86e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NHLBIJJH_00625	9.43e-132	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L4/L1 family
NHLBIJJH_00626	8.72e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NHLBIJJH_00627	1.85e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NHLBIJJH_00628	1.05e-58	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NHLBIJJH_00629	4.05e-152	-	-	-	-	-	-	-	-
NHLBIJJH_00630	4.97e-70	-	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
NHLBIJJH_00631	4.27e-155	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NHLBIJJH_00632	3.42e-97	-	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NHLBIJJH_00633	5.78e-35	-	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L29 protein
NHLBIJJH_00634	2.19e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NHLBIJJH_00635	6.79e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NHLBIJJH_00636	3.74e-204	-	-	-	-	-	-	-	-
NHLBIJJH_00637	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHLBIJJH_00638	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
NHLBIJJH_00639	3.33e-254	-	5.2.1.8	-	O	ko:K03771	-	ko00000,ko01000,ko03110	SurA N-terminal domain
NHLBIJJH_00640	2.38e-167	-	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NHLBIJJH_00641	1.43e-142	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
NHLBIJJH_00647	1.9e-62	-	-	-	L	-	-	-	bacterial (prokaryotic) histone like domain
NHLBIJJH_00648	9.89e-207	-	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
NHLBIJJH_00649	2.43e-126	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
NHLBIJJH_00650	1.45e-172	-	-	-	F	-	-	-	NUDIX domain
NHLBIJJH_00651	4.08e-149	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Putative methyltransferase
NHLBIJJH_00652	1.39e-282	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NHLBIJJH_00653	5.64e-66	-	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
NHLBIJJH_00654	1.53e-184	-	-	-	DTZ	-	-	-	EF-hand, calcium binding motif
NHLBIJJH_00655	6.5e-215	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
NHLBIJJH_00658	9.56e-51	-	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S16
NHLBIJJH_00659	3.13e-128	aroK	2.7.1.71	-	E	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NHLBIJJH_00660	2.96e-242	-	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NHLBIJJH_00661	6.98e-80	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
NHLBIJJH_00662	4.98e-117	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NHLBIJJH_00663	2.73e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NHLBIJJH_00664	1.22e-246	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NHLBIJJH_00665	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
NHLBIJJH_00666	1.17e-116	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NHLBIJJH_00671	0.0	-	-	-	CO	-	-	-	Thioredoxin-like
NHLBIJJH_00672	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
NHLBIJJH_00673	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NHLBIJJH_00674	3.28e-178	kdsB	2.7.7.38	-	M	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NHLBIJJH_00675	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_00677	1.81e-252	ppiD	5.2.1.8	-	O	ko:K03769,ko:K03770,ko:K03771,ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl cis-trans isomerase activity
NHLBIJJH_00678	9.11e-261	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
NHLBIJJH_00679	5.1e-265	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
NHLBIJJH_00682	2.69e-38	-	-	-	T	-	-	-	ribosome binding
NHLBIJJH_00683	3.28e-232	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MlaD protein
NHLBIJJH_00684	3.54e-189	-	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHLBIJJH_00685	5.53e-174	-	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease MlaE
NHLBIJJH_00686	0.0	-	-	-	H	-	-	-	NAD synthase
NHLBIJJH_00687	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
NHLBIJJH_00688	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
NHLBIJJH_00689	0.0	-	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
NHLBIJJH_00690	1.72e-147	-	-	-	M	-	-	-	NLP P60 protein
NHLBIJJH_00691	3.38e-294	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NHLBIJJH_00692	6.61e-313	-	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Tubulin/FtsZ family, GTPase domain
NHLBIJJH_00695	2.89e-234	-	-	-	S	ko:K01128	-	ko00000,ko01000	acid phosphatase activity
NHLBIJJH_00696	4.57e-311	-	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase C-terminal domain
NHLBIJJH_00697	1.53e-219	-	-	-	O	-	-	-	Thioredoxin-like domain
NHLBIJJH_00698	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NHLBIJJH_00699	3.23e-217	-	-	-	EP	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLBIJJH_00700	1.6e-213	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
NHLBIJJH_00701	6.05e-86	-	-	-	S	ko:K09922	-	ko00000	Putative member of DMT superfamily (DUF486)
NHLBIJJH_00702	2.26e-273	-	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	tRNA synthetases class I (W and Y)
NHLBIJJH_00703	5.49e-236	-	-	-	S	ko:K14347	-	ko00000,ko02000,ko04147	SBF-like CPA transporter family (DUF4137)
NHLBIJJH_00706	0.0	-	-	-	S	-	-	-	Large extracellular alpha-helical protein
NHLBIJJH_00707	0.0	-	-	-	M	-	-	-	Aerotolerance regulator N-terminal
NHLBIJJH_00708	2.06e-234	-	-	-	S	-	-	-	Peptidase family M28
NHLBIJJH_00709	1.24e-200	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
NHLBIJJH_00712	2.61e-132	-	-	-	S	-	-	-	Glycosyl hydrolase 108
NHLBIJJH_00714	0.0	-	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	DNA Topoisomerase IV
NHLBIJJH_00715	1.83e-74	-	-	-	-	-	-	-	-
NHLBIJJH_00717	2.56e-187	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NHLBIJJH_00718	7.23e-309	-	-	-	G	-	-	-	cellulose 1,4-beta-cellobiosidase activity
NHLBIJJH_00719	8.19e-81	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
NHLBIJJH_00721	0.0	-	-	-	P	-	-	-	Domain of unknown function
NHLBIJJH_00722	1.7e-297	-	-	-	S	-	-	-	AI-2E family transporter
NHLBIJJH_00723	0.0	rseP	3.4.21.116	-	M	ko:K06399,ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	metalloendopeptidase activity
NHLBIJJH_00724	2.1e-86	-	-	-	-	-	-	-	-
NHLBIJJH_00725	2.63e-267	-	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
NHLBIJJH_00726	0.0	-	-	-	H	ko:K07137	-	ko00000	5-formyltetrahydrofolate cyclo-ligase activity
NHLBIJJH_00728	3.73e-90	-	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR carboxylase
NHLBIJJH_00729	1.15e-122	-	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Phosphoribosyl transferase domain
NHLBIJJH_00730	1.55e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
NHLBIJJH_00731	5.56e-306	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydro-orotase-like
NHLBIJJH_00732	2.15e-168	-	-	-	S	-	-	-	Uncharacterised protein family UPF0066
NHLBIJJH_00733	2.91e-94	-	-	-	K	-	-	-	DNA-binding transcription factor activity
NHLBIJJH_00734	1.04e-283	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHLBIJJH_00735	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NHLBIJJH_00736	1.15e-286	-	-	-	V	-	-	-	Beta-lactamase
NHLBIJJH_00737	2.61e-314	-	-	-	MU	-	-	-	Outer membrane efflux protein
NHLBIJJH_00738	6.6e-311	-	-	-	V	-	-	-	MacB-like periplasmic core domain
NHLBIJJH_00739	8.65e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHLBIJJH_00740	2.88e-283	-	-	-	M	ko:K02005	-	ko00000	HlyD family secretion protein
NHLBIJJH_00742	2.34e-97	nudI	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	GDP-mannose mannosyl hydrolase activity
NHLBIJJH_00743	6.23e-123	-	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
NHLBIJJH_00744	1.16e-244	sun	2.1.1.176, 2.1.1.178	-	J	ko:K03500,ko:K11392	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHLBIJJH_00745	5.66e-230	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NHLBIJJH_00746	1.46e-118	-	-	-	T	-	-	-	Prokaryotic dksA/traR C4-type zinc finger
NHLBIJJH_00747	5.67e-33	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
NHLBIJJH_00748	4.52e-49	-	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S18
NHLBIJJH_00749	3.84e-189	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Type I GTP cyclohydrolase folE2
NHLBIJJH_00750	1.02e-178	-	-	-	S	-	-	-	Cytochrome C assembly protein
NHLBIJJH_00751	4.36e-240	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Glutamyl-tRNAGlu reductase, N-terminal domain
NHLBIJJH_00752	1.7e-234	-	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Porphobilinogen deaminase, dipyromethane cofactor binding domain
NHLBIJJH_00753	8.67e-85	-	-	-	S	-	-	-	Protein of unknown function, DUF488
NHLBIJJH_00754	0.0	-	-	-	M	ko:K02847,ko:K13009,ko:K16705	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
NHLBIJJH_00755	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHLBIJJH_00756	4.07e-52	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
NHLBIJJH_00758	4.42e-09	-	-	-	S	-	-	-	Mac 1
NHLBIJJH_00764	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
NHLBIJJH_00765	1.06e-182	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
NHLBIJJH_00766	0.0	-	-	-	KLT	-	-	-	Sulfatase-modifying factor enzyme 1
NHLBIJJH_00767	3.77e-289	kbl	2.3.1.29	-	E	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
NHLBIJJH_00768	6.25e-122	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
NHLBIJJH_00769	4.07e-232	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
NHLBIJJH_00771	2.95e-122	-	-	-	-	-	-	-	-
NHLBIJJH_00772	3.03e-186	-	-	-	H	ko:K22132	-	ko00000,ko03016	ThiF family
NHLBIJJH_00773	1.45e-190	-	-	-	S	ko:K09769	-	ko00000	YmdB-like protein
NHLBIJJH_00774	1.56e-103	-	-	-	T	-	-	-	Universal stress protein family
NHLBIJJH_00775	1.02e-233	-	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (W and Y)
NHLBIJJH_00776	2.68e-107	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
NHLBIJJH_00777	2.95e-203	-	-	-	GM	-	-	-	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NHLBIJJH_00778	3.69e-166	-	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
NHLBIJJH_00779	2.55e-94	-	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
NHLBIJJH_00780	1.28e-223	-	-	-	CO	-	-	-	amine dehydrogenase activity
NHLBIJJH_00781	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
NHLBIJJH_00782	1.8e-202	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
NHLBIJJH_00783	6e-76	-	-	-	P	ko:K03972	-	ko00000	Rhodanese Homology Domain
NHLBIJJH_00784	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-L-fucosidase
NHLBIJJH_00785	0.0	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
NHLBIJJH_00786	8.21e-246	-	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	ATP:guanido phosphotransferase, C-terminal catalytic domain
NHLBIJJH_00787	5.46e-126	-	-	-	S	ko:K19411	-	ko00000	UvrB/uvrC motif
NHLBIJJH_00788	3.84e-180	-	-	-	P	ko:K09819	-	ko00000,ko00002,ko02000	FecCD transport family
NHLBIJJH_00789	1.77e-191	-	-	-	P	ko:K09820	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NHLBIJJH_00790	2.03e-100	-	-	-	-	-	-	-	-
NHLBIJJH_00791	4.14e-229	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
NHLBIJJH_00792	0.0	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
NHLBIJJH_00793	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
NHLBIJJH_00794	2.98e-136	leuA	2.3.3.13	-	H	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NHLBIJJH_00796	0.0	-	-	-	V	-	-	-	MatE
NHLBIJJH_00797	4.33e-161	menG	2.1.1.163, 2.1.1.201	-	Q	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	ubiE/COQ5 methyltransferase family
NHLBIJJH_00801	2.42e-197	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NHLBIJJH_00802	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHLBIJJH_00803	2.35e-213	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NHLBIJJH_00804	3.95e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NHLBIJJH_00806	2.03e-308	-	-	-	E	ko:K03310	-	ko00000	Sodium:alanine symporter family
NHLBIJJH_00807	9.91e-95	-	-	-	K	-	-	-	-acetyltransferase
NHLBIJJH_00808	8.6e-222	-	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Glutaminase
NHLBIJJH_00809	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
NHLBIJJH_00810	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_00814	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Prolyl-tRNA synthetase, C-terminal
NHLBIJJH_00815	2.04e-158	-	-	-	S	-	-	-	Peptidase family M50
NHLBIJJH_00817	6.79e-217	-	-	-	JM	-	-	-	Nucleotidyl transferase
NHLBIJJH_00818	8.25e-273	-	-	-	S	-	-	-	Phosphotransferase enzyme family
NHLBIJJH_00819	3.51e-223	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
NHLBIJJH_00821	0.0	-	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
NHLBIJJH_00822	1.18e-295	-	-	-	-	-	-	-	-
NHLBIJJH_00823	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_00824	1.03e-138	mntP	-	-	P	-	-	-	manganese ion transmembrane transporter activity
NHLBIJJH_00826	3.29e-187	-	-	-	S	-	-	-	Phenazine biosynthesis-like protein
NHLBIJJH_00827	2.83e-177	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NHLBIJJH_00828	3.58e-316	-	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, Activator interacting domain (AID)
NHLBIJJH_00829	5.48e-273	ycaD	-	-	EGP	ko:K08219	-	ko00000,ko02000	Major facilitator Superfamily
NHLBIJJH_00830	2.58e-226	-	3.4.11.10, 3.4.11.6	-	DZ	ko:K19701	-	ko00000,ko01000,ko01002	aminopeptidase activity
NHLBIJJH_00831	9.51e-287	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
NHLBIJJH_00832	0.0	-	-	-	S	-	-	-	inositol 2-dehydrogenase activity
NHLBIJJH_00834	1.65e-286	-	3.6.4.13	-	L	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	helicase superfamily c-terminal domain
NHLBIJJH_00836	3.6e-145	-	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
NHLBIJJH_00837	0.0	-	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NHLBIJJH_00838	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
NHLBIJJH_00839	9.77e-278	-	4.2.1.51, 5.4.99.5	-	E	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
NHLBIJJH_00840	3.72e-237	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NHLBIJJH_00841	4.51e-190	-	-	-	S	-	-	-	NIF3 (NGG1p interacting factor 3)
NHLBIJJH_00842	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
NHLBIJJH_00843	0.0	-	-	-	N	-	-	-	ABC-type uncharacterized transport system
NHLBIJJH_00844	2.49e-183	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NHLBIJJH_00845	1.09e-223	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NHLBIJJH_00846	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NHLBIJJH_00847	2.78e-132	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	nUDIX hydrolase
NHLBIJJH_00849	7.86e-41	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
NHLBIJJH_00850	2.16e-21	traC	-	-	P	-	-	-	DNA integration
NHLBIJJH_00851	8.13e-06	-	-	-	L	ko:K07505	-	ko00000	Primase C terminal 2 (PriCT-2)
NHLBIJJH_00852	7.09e-65	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
NHLBIJJH_00854	7.24e-24	-	-	-	-	-	-	-	-
NHLBIJJH_00862	2.78e-06	-	-	-	-	-	-	-	-
NHLBIJJH_00864	2.14e-10	-	-	-	K	ko:K07726	-	ko00000,ko03000	Transcriptional regulator
NHLBIJJH_00865	1.25e-30	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
NHLBIJJH_00882	1.08e-19	-	-	-	OU	-	-	-	Belongs to the peptidase S14 family
NHLBIJJH_00885	5.31e-42	-	-	-	S	-	-	-	Phage terminase large subunit (GpA)
NHLBIJJH_00887	2.89e-251	-	2.3.1.1	-	E	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
NHLBIJJH_00888	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHLBIJJH_00889	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NHLBIJJH_00891	2.11e-173	-	6.3.5.11, 6.3.5.9	-	V	ko:K02224,ko:K18554	ko00860,ko01100,ko01120,map00860,map01100,map01120	br01600,ko00000,ko00001,ko01000,ko01504	Chloramphenicol phosphotransferase-like protein
NHLBIJJH_00892	1.12e-83	-	-	-	K	ko:K07343	-	ko00000	positive regulation of type IV pilus biogenesis
NHLBIJJH_00893	5.44e-232	-	-	-	CO	-	-	-	Redoxin
NHLBIJJH_00894	1.73e-123	paiA	-	-	K	-	-	-	acetyltransferase
NHLBIJJH_00895	2.27e-216	-	-	-	K	-	-	-	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
NHLBIJJH_00897	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
NHLBIJJH_00900	0.0	-	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
NHLBIJJH_00901	0.0	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
NHLBIJJH_00910	0.0	-	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
NHLBIJJH_00911	8.25e-131	-	-	-	D	ko:K06287	-	ko00000	Maf-like protein
NHLBIJJH_00912	2.66e-290	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHLBIJJH_00914	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
NHLBIJJH_00915	0.0	-	-	-	GK	-	-	-	carbohydrate kinase activity
NHLBIJJH_00916	4.34e-202	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NHLBIJJH_00917	2.33e-207	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NHLBIJJH_00918	0.0	-	-	-	I	-	-	-	Acetyltransferase (GNAT) domain
NHLBIJJH_00919	1.14e-142	-	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Cytidylate kinase
NHLBIJJH_00920	8.17e-147	-	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
NHLBIJJH_00921	5.24e-258	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NHLBIJJH_00922	1.47e-118	actI	1.5.1.36	-	S	ko:K00484	ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220	ko00000,ko00001,ko01000	FMN binding
NHLBIJJH_00923	3.86e-162	rnc	3.1.26.3	-	K	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NHLBIJJH_00924	0.0	-	-	-	P	ko:K07221	-	ko00000,ko02000	Phosphate-selective porin O and P
NHLBIJJH_00925	3e-263	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
NHLBIJJH_00927	2.11e-272	-	-	-	S	-	-	-	regulation of ryanodine-sensitive calcium-release channel activity
NHLBIJJH_00929	5.3e-229	-	-	-	M	-	-	-	lytic endotransglycosylase activity
NHLBIJJH_00930	3.86e-18	-	-	-	-	-	-	-	-
NHLBIJJH_00931	5.35e-181	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
NHLBIJJH_00932	1.19e-163	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Tetrapyrrole (Corrin/Porphyrin) Methylases
NHLBIJJH_00933	3.06e-115	-	-	-	S	-	-	-	Lipopolysaccharide-assembly
NHLBIJJH_00934	1.18e-170	-	-	-	S	ko:K05807	-	ko00000,ko02000	Outer membrane lipoprotein
NHLBIJJH_00935	4.98e-117	hisI	3.5.4.19	-	E	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-AMP cyclohydrolase
NHLBIJJH_00936	3.12e-224	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
NHLBIJJH_00937	4.91e-121	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	G/U mismatch-specific uracil-DNA glycosylase activity
NHLBIJJH_00938	4.18e-195	-	-	-	-	-	-	-	-
NHLBIJJH_00939	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
NHLBIJJH_00940	3.15e-137	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
NHLBIJJH_00942	1.45e-181	-	-	-	Q	-	-	-	methyltransferase activity
NHLBIJJH_00943	0.0	-	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	NAD synthase
NHLBIJJH_00944	2.28e-79	-	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
NHLBIJJH_00946	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	exo-alpha-(2->6)-sialidase activity
NHLBIJJH_00947	3.01e-276	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
NHLBIJJH_00948	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR/Asp-box repeat
NHLBIJJH_00949	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
NHLBIJJH_00950	2.36e-36	-	-	-	KLT	-	-	-	Protein kinase domain
NHLBIJJH_00954	3.31e-83	-	-	-	L	-	-	-	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHLBIJJH_00956	9.06e-242	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NHLBIJJH_00957	9.5e-239	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHLBIJJH_00958	1.24e-280	-	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NHLBIJJH_00959	2.31e-258	MA20_42350	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyl transferase, family 2
NHLBIJJH_00960	7.95e-250	-	-	-	M	-	-	-	Glycosyl transferase, family 2
NHLBIJJH_00961	7.54e-242	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
NHLBIJJH_00963	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
NHLBIJJH_00964	1.51e-287	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NHLBIJJH_00965	4.02e-284	-	-	-	M	-	-	-	Glycosyl transferases group 1
NHLBIJJH_00966	3.73e-144	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
NHLBIJJH_00967	8.57e-272	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
NHLBIJJH_00968	2.94e-184	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NHLBIJJH_00969	9.24e-207	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHLBIJJH_00970	2.72e-263	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NHLBIJJH_00971	3.43e-315	mnmE	-	-	J	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NHLBIJJH_00972	4.35e-93	-	-	-	V	-	-	-	endonuclease activity
NHLBIJJH_00973	1.85e-146	-	-	-	S	-	-	-	UPF0126 domain
NHLBIJJH_00974	5.27e-189	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
NHLBIJJH_00975	4.54e-105	-	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NHLBIJJH_00976	0.0	rsmH	2.1.1.199	-	M	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NHLBIJJH_00978	0.0	-	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein dimerisation domain
NHLBIJJH_00979	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHLBIJJH_00980	0.0	-	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Mur ligase middle domain
NHLBIJJH_00981	1.99e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHLBIJJH_00982	2.92e-314	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHLBIJJH_00983	4.07e-160	mltD	-	CBM50	M	ko:K08307,ko:K12204,ko:K19224	-	ko00000,ko01000,ko01002,ko01011,ko02044	LysM domain
NHLBIJJH_00984	1.33e-277	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Cell cycle protein
NHLBIJJH_00985	2.26e-266	-	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NHLBIJJH_00986	0.0	murB	-	-	M	-	-	-	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
NHLBIJJH_00987	1.44e-228	ddl	6.3.2.4	-	M	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	D-ala D-ala ligase N-terminus
NHLBIJJH_00988	1.48e-215	-	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	POTRA domain, FtsQ-type
NHLBIJJH_00989	1.15e-238	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NHLBIJJH_00990	6.69e-239	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
NHLBIJJH_00991	7.14e-141	-	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
NHLBIJJH_00992	0.0	-	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase family (aconitate hydratase)
NHLBIJJH_00993	1.53e-146	-	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
NHLBIJJH_00994	4.99e-274	-	-	-	-	-	-	-	-
NHLBIJJH_00995	0.0	-	-	-	O	-	-	-	Trypsin
NHLBIJJH_00996	0.0	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
NHLBIJJH_00997	5.91e-280	-	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate synthase
NHLBIJJH_00998	3.61e-172	-	-	-	E	-	-	-	ATPases associated with a variety of cellular activities
NHLBIJJH_00999	2.05e-198	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NHLBIJJH_01000	5.88e-163	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S2
NHLBIJJH_01001	2.43e-165	cbiX	4.99.1.3	-	S	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	sirohydrochlorin cobaltochelatase activity
NHLBIJJH_01002	6.68e-198	-	2.5.1.55	-	M	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	DAHP synthetase I family
NHLBIJJH_01005	6.31e-171	-	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NHLBIJJH_01006	6.55e-221	-	-	-	E	-	-	-	Phosphoserine phosphatase
NHLBIJJH_01007	0.0	-	6.3.2.45	-	M	ko:K02558	-	ko00000,ko01000	Mur ligase family, catalytic domain
NHLBIJJH_01008	4.42e-306	-	-	-	M	-	-	-	OmpA family
NHLBIJJH_01009	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
NHLBIJJH_01010	2.27e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NHLBIJJH_01011	1.31e-114	ywrF	-	-	S	-	-	-	FMN binding
NHLBIJJH_01012	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NHLBIJJH_01013	0.0	-	-	-	T	-	-	-	pathogenesis
NHLBIJJH_01015	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
NHLBIJJH_01016	7.81e-316	-	-	-	-	-	-	-	-
NHLBIJJH_01017	5.12e-71	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
NHLBIJJH_01019	1.1e-160	-	-	-	S	-	-	-	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NHLBIJJH_01020	9.82e-262	-	-	-	M	ko:K02022	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHLBIJJH_01021	1.7e-301	-	4.2.1.129, 5.4.99.17, 5.5.1.16	-	I	ko:K06045,ko:K17811	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
NHLBIJJH_01022	5.98e-316	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
NHLBIJJH_01023	1.8e-296	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
NHLBIJJH_01024	5.69e-287	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
NHLBIJJH_01027	1.31e-213	-	-	-	K	-	-	-	LysR substrate binding domain
NHLBIJJH_01028	5.45e-234	-	-	-	S	-	-	-	Conserved hypothetical protein 698
NHLBIJJH_01029	7.38e-252	-	-	-	E	-	-	-	Aminotransferase class-V
NHLBIJJH_01030	2.2e-313	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
NHLBIJJH_01031	0.0	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NHLBIJJH_01032	6.62e-182	-	2.7.13.3	-	Q	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Transposase
NHLBIJJH_01033	4.88e-169	-	4.3.99.3	-	O	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NHLBIJJH_01034	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NHLBIJJH_01035	5.84e-173	-	-	-	K	-	-	-	Transcriptional regulator
NHLBIJJH_01036	0.0	-	-	-	P	-	-	-	Dimerisation domain of Zinc Transporter
NHLBIJJH_01037	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
NHLBIJJH_01039	1.36e-242	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NHLBIJJH_01040	1.79e-201	-	-	-	S	-	-	-	SigmaW regulon antibacterial
NHLBIJJH_01042	2.02e-173	-	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiG
NHLBIJJH_01043	1.39e-295	-	-	-	E	-	-	-	Amino acid permease
NHLBIJJH_01044	3.42e-157	gph	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
NHLBIJJH_01045	6.62e-257	-	-	-	S	ko:K11744	-	ko00000	AI-2E family transporter
NHLBIJJH_01046	4.44e-310	-	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
NHLBIJJH_01047	1.32e-235	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NHLBIJJH_01048	0.0	-	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
NHLBIJJH_01049	8.55e-214	-	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NHLBIJJH_01050	5.11e-222	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
NHLBIJJH_01051	3.82e-128	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NHLBIJJH_01052	4.55e-137	-	-	-	T	-	-	-	histone H2A K63-linked ubiquitination
NHLBIJJH_01054	3.23e-253	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHLBIJJH_01055	2.84e-286	-	-	-	S	-	-	-	Phosphotransferase enzyme family
NHLBIJJH_01056	1.55e-254	-	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NHLBIJJH_01057	1.46e-266	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
NHLBIJJH_01059	1.22e-27	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_01060	6.82e-16	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_01062	1.11e-113	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_01063	6.82e-16	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_01067	5.9e-26	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_01068	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_01069	1.43e-120	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
NHLBIJJH_01070	0.0	-	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase / GMP reductase domain
NHLBIJJH_01071	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	GMP synthase C terminal domain
NHLBIJJH_01072	1.85e-137	-	-	-	S	-	-	-	Maltose acetyltransferase
NHLBIJJH_01073	4.52e-153	ppaX_1	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
NHLBIJJH_01074	7.72e-178	-	-	-	S	-	-	-	NYN domain
NHLBIJJH_01075	7.17e-233	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NHLBIJJH_01076	2.5e-126	-	-	-	-	-	-	-	-
NHLBIJJH_01077	6.87e-256	-	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NHLBIJJH_01078	1.15e-151	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
NHLBIJJH_01079	2.72e-76	-	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
NHLBIJJH_01080	9e-65	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NHLBIJJH_01081	1.42e-219	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
NHLBIJJH_01082	9.36e-171	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHLBIJJH_01083	2.08e-241	-	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
NHLBIJJH_01085	1.08e-209	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
NHLBIJJH_01086	9.15e-244	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
NHLBIJJH_01087	1.37e-248	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NHLBIJJH_01088	4.5e-234	-	-	GT9	M	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	ADP-heptose-lipopolysaccharide heptosyltransferase activity
NHLBIJJH_01089	1.31e-244	-	5.1.3.20	-	M	ko:K03274	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-beta hydroxysteroid dehydrogenase/isomerase family
NHLBIJJH_01090	6.72e-289	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NHLBIJJH_01091	4.92e-203	-	-	-	-	-	-	-	-
NHLBIJJH_01092	1.59e-305	-	-	-	M	-	-	-	Glycosyl transferases group 1
NHLBIJJH_01093	2.11e-252	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
NHLBIJJH_01094	0.0	-	-	-	I	-	-	-	Acyltransferase family
NHLBIJJH_01095	1.01e-255	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
NHLBIJJH_01098	0.0	-	-	-	P	-	-	-	Citrate transporter
NHLBIJJH_01100	6.56e-112	-	-	-	S	ko:K08999	-	ko00000	Bifunctional nuclease
NHLBIJJH_01101	5.58e-110	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
NHLBIJJH_01102	0.0	-	-	-	E	-	-	-	Transglutaminase-like
NHLBIJJH_01103	2.07e-156	-	-	-	C	-	-	-	Nitroreductase family
NHLBIJJH_01105	0.0	-	3.2.1.23	-	G	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
NHLBIJJH_01106	5.26e-180	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NHLBIJJH_01107	1.69e-242	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
NHLBIJJH_01108	1.41e-289	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
NHLBIJJH_01109	0.0	hsrA	-	-	EGP	-	-	-	Major facilitator Superfamily
NHLBIJJH_01110	2.92e-103	yciA	-	-	I	ko:K10806	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	acyl-coa hydrolase
NHLBIJJH_01113	8.49e-205	-	-	-	IQ	-	-	-	KR domain
NHLBIJJH_01114	5.17e-243	-	-	-	M	-	-	-	Alginate lyase
NHLBIJJH_01115	2.63e-115	-	-	-	L	-	-	-	Staphylococcal nuclease homologues
NHLBIJJH_01118	3.45e-121	-	-	-	K	-	-	-	ParB domain protein nuclease
NHLBIJJH_01119	0.0	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase
NHLBIJJH_01121	1.52e-05	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
NHLBIJJH_01122	3.98e-125	dinD	-	-	S	ko:K14623	-	ko00000,ko03400	Psort location Cytoplasmic, score
NHLBIJJH_01124	2.06e-140	-	-	-	Q	-	-	-	PA14
NHLBIJJH_01127	1.36e-105	-	-	-	-	-	-	-	-
NHLBIJJH_01128	0.0	mmyX	5.3.1.12	-	F	ko:K01812,ko:K07149,ko:K16139	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score
NHLBIJJH_01129	8.23e-112	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Cys-tRNA(Pro) hydrolase activity
NHLBIJJH_01131	6.14e-173	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Glutamine amidotransferase class-I
NHLBIJJH_01132	3e-118	-	-	-	T	ko:K07005	-	ko00000	pyridoxamine 5'-phosphate
NHLBIJJH_01133	1.57e-173	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
NHLBIJJH_01134	1.1e-269	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
NHLBIJJH_01135	1.71e-149	-	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
NHLBIJJH_01136	6.73e-243	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHLBIJJH_01137	3.2e-149	-	4.1.3.38	-	E	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	branched-chain-amino-acid transaminase activity
NHLBIJJH_01138	6.68e-314	-	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
NHLBIJJH_01139	1.38e-223	-	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
NHLBIJJH_01140	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_01141	6.24e-195	-	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NHLBIJJH_01142	0.0	-	-	-	D	-	-	-	Tetratricopeptide repeat
NHLBIJJH_01143	9.87e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NHLBIJJH_01144	0.0	-	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
NHLBIJJH_01145	2.52e-102	MA20_05485	-	-	S	-	-	-	Putative bacterial sensory transduction regulator
NHLBIJJH_01146	1.37e-249	-	-	-	M	-	-	-	HlyD family secretion protein
NHLBIJJH_01147	0.0	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	Helix-hairpin-helix class 2 (Pol1 family) motifs
NHLBIJJH_01150	1.82e-125	-	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Phosphoribosyl transferase domain
NHLBIJJH_01152	2.35e-144	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NHLBIJJH_01153	1.07e-245	-	-	-	S	-	-	-	Imelysin
NHLBIJJH_01154	0.0	-	-	-	C	-	-	-	Di-haem oxidoreductase, putative peroxidase
NHLBIJJH_01155	6.96e-264	-	-	-	J	-	-	-	Endoribonuclease L-PSP
NHLBIJJH_01156	2.96e-217	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
NHLBIJJH_01157	1.23e-228	fatC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
NHLBIJJH_01158	8.69e-180	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NHLBIJJH_01159	1.7e-209	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion transport
NHLBIJJH_01160	5.88e-154	ccs1	-	-	O	ko:K07399	-	ko00000	cytochrome c biogenesis protein
NHLBIJJH_01161	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
NHLBIJJH_01162	3.06e-238	-	-	-	S	-	-	-	Acyltransferase family
NHLBIJJH_01163	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
NHLBIJJH_01164	4.58e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
NHLBIJJH_01165	4.64e-52	-	-	-	C	-	-	-	4Fe-4S single cluster domain of Ferredoxin I
NHLBIJJH_01166	0.0	-	-	GT2	M	ko:K03820	-	ko00000,ko01000	Carbon-nitrogen hydrolase
NHLBIJJH_01167	1.56e-176	-	-	-	S	-	-	-	Phosphodiester glycosidase
NHLBIJJH_01168	1.1e-228	-	2.7.7.13	-	JM	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
NHLBIJJH_01169	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
NHLBIJJH_01170	1.75e-229	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
NHLBIJJH_01171	2.1e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHLBIJJH_01172	8.55e-275	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
NHLBIJJH_01176	9.16e-208	-	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
NHLBIJJH_01177	2.71e-269	-	2.1.1.72	-	H	ko:K07318	-	ko00000,ko01000,ko02048	PFAM D12 class N6 adenine-specific DNA methyltransferase
NHLBIJJH_01179	2.08e-240	BT0173	-	-	S	-	-	-	Psort location Cytoplasmic, score
NHLBIJJH_01180	5.27e-170	BT0174	-	-	C	ko:K04488	-	ko00000	iron-sulfur transferase activity
NHLBIJJH_01181	2.43e-201	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
NHLBIJJH_01183	2.38e-99	cysJ	1.8.1.2	-	C	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	hydroxylamine reductase activity
NHLBIJJH_01185	1.25e-261	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NHLBIJJH_01186	1.33e-52	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHLBIJJH_01187	4.73e-303	-	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
NHLBIJJH_01188	2.29e-315	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NHLBIJJH_01189	1.28e-85	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
NHLBIJJH_01192	2.05e-191	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin resistance protein BacA
NHLBIJJH_01193	7.46e-238	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NHLBIJJH_01194	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHLBIJJH_01195	0.0	kefA	-	-	M	ko:K05802,ko:K22051	-	ko00000,ko02000	cellular water homeostasis
NHLBIJJH_01196	1.78e-97	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	QueF-like protein
NHLBIJJH_01197	1.02e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Queuosine biosynthesis protein QueC
NHLBIJJH_01198	9.88e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NHLBIJJH_01199	0.0	-	-	-	J	-	-	-	Beta-Casp domain
NHLBIJJH_01200	1.23e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
NHLBIJJH_01201	3.02e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
NHLBIJJH_01202	5.54e-306	-	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
NHLBIJJH_01203	9.26e-270	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
NHLBIJJH_01204	2.38e-52	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHLBIJJH_01206	0.0	-	-	-	C	-	-	-	Cytochrome c
NHLBIJJH_01207	4.3e-296	-	-	-	P	-	-	-	ABC-type Zn2 transport system, periplasmic component surface adhesin
NHLBIJJH_01208	7.47e-156	-	-	-	C	-	-	-	Cytochrome c
NHLBIJJH_01210	3.89e-313	-	-	-	C	ko:K00185	-	ko00000	Polysulphide reductase, NrfD
NHLBIJJH_01211	2.46e-249	-	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	chorismate binding enzyme
NHLBIJJH_01212	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 31
NHLBIJJH_01213	0.0	-	-	-	G	-	-	-	Glycosyl transferase 4-like domain
NHLBIJJH_01214	8.59e-293	-	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 57
NHLBIJJH_01215	8.02e-130	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHLBIJJH_01216	4.28e-92	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
NHLBIJJH_01217	2.29e-136	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
NHLBIJJH_01218	9.17e-284	-	5.4.99.22	-	M	ko:K06178	-	ko00000,ko01000,ko03009	translation initiation factor activity
NHLBIJJH_01219	3.77e-118	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
NHLBIJJH_01220	4.11e-314	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
NHLBIJJH_01221	1.12e-142	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
NHLBIJJH_01222	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate--tetrahydrofolate ligase
NHLBIJJH_01223	9.98e-223	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase PanE/ApbA C terminal
NHLBIJJH_01224	1.65e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
NHLBIJJH_01225	1.4e-185	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
NHLBIJJH_01226	0.0	-	-	-	EP	ko:K13894	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLBIJJH_01227	0.0	-	-	-	P	ko:K13895	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLBIJJH_01228	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NHLBIJJH_01229	9.42e-232	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
NHLBIJJH_01230	5.33e-243	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
NHLBIJJH_01231	2.2e-274	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHLBIJJH_01233	6.56e-110	-	-	-	L	-	-	-	endonuclease activity
NHLBIJJH_01234	1.2e-205	-	-	-	EG	-	-	-	EamA-like transporter family
NHLBIJJH_01235	8.96e-268	-	-	-	Q	-	-	-	Multicopper oxidase
NHLBIJJH_01236	0.0	-	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
NHLBIJJH_01237	1.49e-233	-	-	-	O	-	-	-	Parallel beta-helix repeats
NHLBIJJH_01238	1e-219	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
NHLBIJJH_01240	1.07e-138	-	-	-	K	-	-	-	ECF sigma factor
NHLBIJJH_01241	4.23e-218	ytpP	2.7.1.180, 5.3.4.1	-	CO	ko:K01829,ko:K03671,ko:K03734,ko:K06196	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko02000,ko03110	cell redox homeostasis
NHLBIJJH_01242	0.0	-	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	ThiC-associated domain
NHLBIJJH_01243	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
NHLBIJJH_01244	7.29e-60	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
NHLBIJJH_01245	4.61e-56	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
NHLBIJJH_01246	1.45e-133	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
NHLBIJJH_01247	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	N-terminal domain of BNR-repeat neuraminidase
NHLBIJJH_01248	2.34e-123	-	-	-	-	-	-	-	-
NHLBIJJH_01249	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
NHLBIJJH_01250	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
NHLBIJJH_01252	0.0	-	2.7.1.51	-	G	ko:K00879	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
NHLBIJJH_01253	3.59e-202	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
NHLBIJJH_01255	0.0	-	-	-	M	-	-	-	AsmA-like C-terminal region
NHLBIJJH_01256	7.48e-171	-	-	-	S	ko:K06911	-	ko00000	Pirin
NHLBIJJH_01258	8.36e-173	-	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	FtsJ-like methyltransferase
NHLBIJJH_01261	3.34e-214	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHLBIJJH_01262	2.73e-284	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
NHLBIJJH_01263	4.7e-57	-	-	-	S	ko:K06960	-	ko00000	KH domain
NHLBIJJH_01264	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_01265	0.0	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	RNA cap guanine-N2 methyltransferase
NHLBIJJH_01266	7.51e-217	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
NHLBIJJH_01267	3.32e-241	-	4.2.1.113	-	M	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Mandelate Racemase Muconate Lactonizing
NHLBIJJH_01268	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
NHLBIJJH_01270	0.0	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
NHLBIJJH_01271	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
NHLBIJJH_01272	2.74e-101	-	-	-	G	-	-	-	single-species biofilm formation
NHLBIJJH_01273	7.97e-113	-	-	-	K	ko:K13640	-	ko00000,ko03000	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
NHLBIJJH_01274	4.8e-128	-	-	-	S	-	-	-	Flavodoxin-like fold
NHLBIJJH_01275	2.72e-189	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
NHLBIJJH_01276	8.08e-100	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
NHLBIJJH_01277	9.98e-129	-	-	-	C	-	-	-	FMN binding
NHLBIJJH_01278	4.2e-264	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
NHLBIJJH_01279	9.99e-269	-	-	-	C	-	-	-	Aldo/keto reductase family
NHLBIJJH_01280	1.65e-265	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
NHLBIJJH_01281	1.93e-207	-	-	-	S	-	-	-	Aldo/keto reductase family
NHLBIJJH_01282	9.88e-239	-	1.2.7.3	-	-	ko:K00176,ko:K07138	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	-
NHLBIJJH_01283	6.91e-302	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
NHLBIJJH_01284	2.29e-141	-	-	-	M	-	-	-	polygalacturonase activity
NHLBIJJH_01286	3.29e-192	-	-	-	KT	-	-	-	Peptidase S24-like
NHLBIJJH_01287	4.07e-290	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
NHLBIJJH_01290	6.57e-176	-	-	-	O	-	-	-	Trypsin
NHLBIJJH_01291	1.64e-239	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
NHLBIJJH_01292	6.2e-203	-	-	-	-	-	-	-	-
NHLBIJJH_01293	0.0	-	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
NHLBIJJH_01294	1.3e-282	-	-	-	S	-	-	-	Tetratricopeptide repeat
NHLBIJJH_01296	2.63e-10	-	-	-	-	-	-	-	-
NHLBIJJH_01298	8.23e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHLBIJJH_01299	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NHLBIJJH_01300	2.48e-228	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NHLBIJJH_01301	4.38e-211	-	-	-	S	-	-	-	Protein of unknown function DUF58
NHLBIJJH_01302	1.98e-134	-	-	-	-	-	-	-	-
NHLBIJJH_01303	4.64e-229	-	-	-	S	-	-	-	Protein of unknown function (DUF1194)
NHLBIJJH_01305	1.39e-17	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_01307	2.52e-73	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_01308	5.31e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NHLBIJJH_01309	1.74e-176	-	-	-	S	-	-	-	Lysin motif
NHLBIJJH_01310	3.5e-132	-	-	-	-	-	-	-	-
NHLBIJJH_01311	8.56e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
NHLBIJJH_01312	7.16e-174	coaX	2.7.1.33	-	K	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Type III pantothenate kinase
NHLBIJJH_01313	1.18e-273	-	-	-	M	-	-	-	Monogalactosyldiacylglycerol (MGDG) synthase
NHLBIJJH_01314	3.02e-227	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NHLBIJJH_01315	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
NHLBIJJH_01317	0.0	-	-	-	S	ko:K03307	-	ko00000	Sodium:solute symporter family
NHLBIJJH_01318	3.1e-284	-	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Galactokinase galactose-binding signature
NHLBIJJH_01319	0.0	-	-	-	M	-	-	-	Bacterial sugar transferase
NHLBIJJH_01320	7.33e-143	-	-	-	S	-	-	-	RNA recognition motif
NHLBIJJH_01321	3.54e-185	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NHLBIJJH_01322	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_01324	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
NHLBIJJH_01325	3.43e-129	-	-	-	C	-	-	-	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein
NHLBIJJH_01326	1.32e-218	-	-	-	C	-	-	-	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein
NHLBIJJH_01327	6.94e-205	-	-	-	S	-	-	-	Domain of unknown function (DUF362)
NHLBIJJH_01328	1.49e-135	-	-	-	J	-	-	-	Putative rRNA methylase
NHLBIJJH_01329	5.54e-141	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NHLBIJJH_01330	3.07e-194	-	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
NHLBIJJH_01331	5.58e-289	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	NusA-like KH domain
NHLBIJJH_01332	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NHLBIJJH_01333	2e-82	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NHLBIJJH_01335	0.0	-	-	-	P	-	-	-	PA14 domain
NHLBIJJH_01336	3.57e-15	-	-	-	-	-	-	-	-
NHLBIJJH_01337	1.12e-150	-	-	-	-	-	-	-	-
NHLBIJJH_01338	0.0	-	-	-	T	-	-	-	5TM C-terminal transporter carbon starvation CstA
NHLBIJJH_01339	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
NHLBIJJH_01340	8.17e-135	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHLBIJJH_01341	4.34e-284	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NHLBIJJH_01342	9.28e-229	-	-	-	C	-	-	-	e3 binding domain
NHLBIJJH_01343	5.37e-126	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
NHLBIJJH_01344	2.52e-264	-	-	-	S	-	-	-	PFAM glycosyl transferase family 2
NHLBIJJH_01345	4.79e-292	-	-	-	-	-	-	-	-
NHLBIJJH_01346	1.1e-259	-	-	-	S	-	-	-	Glycosyltransferase like family 2
NHLBIJJH_01347	3.06e-226	-	-	-	S	-	-	-	Glycosyl transferase family 11
NHLBIJJH_01348	9.64e-188	-	-	GT2	S	ko:K19427	-	ko00000,ko01000	PFAM glycosyl transferase family 2
NHLBIJJH_01351	7.69e-277	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
NHLBIJJH_01352	0.0	-	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Polyphosphate kinase middle domain
NHLBIJJH_01353	0.0	-	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
NHLBIJJH_01354	4.9e-265	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
NHLBIJJH_01355	1.29e-192	map	3.4.11.18	-	J	ko:K01265	-	ko00000,ko01000,ko01002	Metallopeptidase family M24
NHLBIJJH_01356	6.41e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NHLBIJJH_01357	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NHLBIJJH_01359	2.62e-100	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
NHLBIJJH_01360	3.38e-102	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NHLBIJJH_01361	2.38e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NHLBIJJH_01362	2.25e-105	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NHLBIJJH_01363	4.08e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NHLBIJJH_01364	5.36e-138	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NHLBIJJH_01365	1.53e-47	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S L24/mitochondrial 39S L24
NHLBIJJH_01366	1.15e-205	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHLBIJJH_01367	1.77e-124	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
NHLBIJJH_01368	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
NHLBIJJH_01369	0.0	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 Helicase protein
NHLBIJJH_01370	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NHLBIJJH_01372	5.34e-287	-	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
NHLBIJJH_01373	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Collagenase
NHLBIJJH_01375	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NHLBIJJH_01376	6.52e-75	-	-	-	L	-	-	-	Cupin 2, conserved barrel domain protein
NHLBIJJH_01377	1.18e-128	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
NHLBIJJH_01379	3.03e-296	-	-	-	EGP	-	-	-	Major facilitator Superfamily
NHLBIJJH_01380	1.93e-214	-	-	-	K	-	-	-	LysR substrate binding domain
NHLBIJJH_01381	1.17e-271	-	-	-	S	-	-	-	tRNA-splicing ligase RtcB
NHLBIJJH_01382	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
NHLBIJJH_01384	6.16e-285	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHLBIJJH_01385	4.44e-134	-	-	-	D	-	-	-	ErfK ybiS ycfS ynhG family protein
NHLBIJJH_01386	0.0	-	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
NHLBIJJH_01387	8.8e-169	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
NHLBIJJH_01391	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Bacterial DNA topoisomeraes I ATP-binding domain
NHLBIJJH_01392	9.54e-102	-	-	-	-	-	-	-	-
NHLBIJJH_01393	0.0	-	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase HemD
NHLBIJJH_01394	6.42e-101	-	-	-	S	-	-	-	peptidase
NHLBIJJH_01395	8.59e-171	-	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
NHLBIJJH_01396	2.1e-99	-	-	-	S	-	-	-	peptidase
NHLBIJJH_01397	0.0	-	-	-	S	-	-	-	pathogenesis
NHLBIJJH_01398	0.0	-	-	-	V	ko:K18095	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	AcrB/AcrD/AcrF family
NHLBIJJH_01399	1e-242	-	-	-	M	ko:K18094	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	Biotin-lipoyl like
NHLBIJJH_01400	2.52e-197	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
NHLBIJJH_01401	6.82e-223	-	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
NHLBIJJH_01402	9.47e-236	-	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
NHLBIJJH_01403	1.63e-298	-	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
NHLBIJJH_01404	9.53e-206	-	-	-	S	ko:K09949	-	ko00000	Protein of unknown function (DUF1009)
NHLBIJJH_01407	1.34e-90	-	-	-	-	-	-	-	-
NHLBIJJH_01408	2.28e-170	yyaQ	-	-	V	-	-	-	Protein conserved in bacteria
NHLBIJJH_01409	2.51e-192	-	-	-	M	-	-	-	Glycosyl transferase WecB/TagA/CpsF family
NHLBIJJH_01410	1.06e-189	-	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Metallo-beta-lactamase superfamily
NHLBIJJH_01411	0.0	-	-	-	L	ko:K03631	-	ko00000,ko03400	RecF/RecN/SMC N terminal domain
NHLBIJJH_01412	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
NHLBIJJH_01413	7.53e-241	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
NHLBIJJH_01414	9.29e-132	-	-	-	J	ko:K02356	-	ko00000,ko03012	Elongation factor P (EF-P) OB domain
NHLBIJJH_01416	1.2e-105	-	-	-	S	-	-	-	ACT domain protein
NHLBIJJH_01417	4.8e-313	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
NHLBIJJH_01418	3.06e-85	-	-	-	M	ko:K03282	-	ko00000,ko02000	Large-conductance mechanosensitive channel, MscL
NHLBIJJH_01419	1.18e-276	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
NHLBIJJH_01420	4.06e-287	-	-	-	EGP	-	-	-	Major facilitator Superfamily
NHLBIJJH_01421	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
NHLBIJJH_01422	8.88e-268	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
NHLBIJJH_01424	1.96e-121	ngr	-	-	C	-	-	-	Rubrerythrin
NHLBIJJH_01425	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1705)
NHLBIJJH_01426	0.0	-	-	-	M	-	-	-	Glycosyl Hydrolase Family 88
NHLBIJJH_01427	0.0	-	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
NHLBIJJH_01428	1.55e-42	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	CTP reductase activity
NHLBIJJH_01429	1.07e-188	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
NHLBIJJH_01430	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
NHLBIJJH_01431	0.0	-	-	-	T	-	-	-	Histidine kinase
NHLBIJJH_01432	1.33e-110	-	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
NHLBIJJH_01433	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
NHLBIJJH_01434	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
NHLBIJJH_01435	7.36e-55	himA	-	-	L	ko:K03530,ko:K04764,ko:K05788	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
NHLBIJJH_01436	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_01439	6.96e-305	-	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	tRNA (Uracil-5-)-methyltransferase
NHLBIJJH_01440	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NHLBIJJH_01441	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
NHLBIJJH_01442	3.29e-258	-	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
NHLBIJJH_01443	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
NHLBIJJH_01444	2.43e-203	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NHLBIJJH_01445	2.46e-307	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHLBIJJH_01446	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_01447	3.55e-163	-	-	-	S	-	-	-	SWIM zinc finger
NHLBIJJH_01448	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase C-terminal
NHLBIJJH_01449	0.0	-	-	-	U	ko:K03321	-	ko00000,ko02000	Sulfate permease family
NHLBIJJH_01450	7.2e-125	-	-	-	-	-	-	-	-
NHLBIJJH_01451	1.04e-109	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NHLBIJJH_01452	0.0	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
NHLBIJJH_01456	0.0	-	-	-	M	-	-	-	pathogenesis
NHLBIJJH_01458	3.06e-264	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
NHLBIJJH_01464	2.66e-148	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
NHLBIJJH_01467	0.0	-	-	-	P	-	-	-	Cation transport protein
NHLBIJJH_01468	8.29e-299	-	-	-	V	ko:K03327	-	ko00000,ko02000	drug transmembrane transporter activity
NHLBIJJH_01469	7.41e-120	-	-	-	-	-	-	-	-
NHLBIJJH_01470	9.86e-54	-	-	-	-	-	-	-	-
NHLBIJJH_01471	2.93e-102	-	-	-	-	-	-	-	-
NHLBIJJH_01472	0.0	-	2.1.1.182	-	IJ	ko:K02528	-	ko00000,ko01000,ko03009	Ribosomal RNA adenine dimethylases
NHLBIJJH_01473	1.04e-246	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
NHLBIJJH_01474	0.0	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
NHLBIJJH_01475	0.0	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
NHLBIJJH_01476	6.39e-119	-	-	-	T	-	-	-	STAS domain
NHLBIJJH_01477	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2851)
NHLBIJJH_01478	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
NHLBIJJH_01479	1.86e-291	-	-	-	-	-	-	-	-
NHLBIJJH_01480	0.0	-	-	-	M	-	-	-	Sulfatase
NHLBIJJH_01481	2.33e-286	-	4.1.99.19	-	H	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Biotin and Thiamin Synthesis associated domain
NHLBIJJH_01482	1.39e-206	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
NHLBIJJH_01483	2.1e-271	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
NHLBIJJH_01484	0.0	-	-	-	T	-	-	-	pathogenesis
NHLBIJJH_01485	0.0	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Dehydratase family
NHLBIJJH_01486	2.81e-167	-	-	-	T	ko:K07657	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
NHLBIJJH_01487	3.49e-288	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
NHLBIJJH_01491	2.09e-10	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
NHLBIJJH_01492	9.15e-206	hisG	2.4.2.17	-	E	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
NHLBIJJH_01493	2.04e-314	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
NHLBIJJH_01494	4.87e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF3313)
NHLBIJJH_01495	8.4e-260	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NHLBIJJH_01496	2.69e-255	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
NHLBIJJH_01497	2.8e-169	-	-	-	-	-	-	-	-
NHLBIJJH_01498	0.0	-	-	-	NU	-	-	-	Type IV pilus assembly protein PilM;
NHLBIJJH_01499	1.5e-208	-	-	-	-	-	-	-	-
NHLBIJJH_01500	2.27e-245	-	-	-	-	-	-	-	-
NHLBIJJH_01501	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
NHLBIJJH_01502	5.32e-142	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHLBIJJH_01503	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NHLBIJJH_01504	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
NHLBIJJH_01505	4.04e-241	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NHLBIJJH_01506	1.1e-131	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NHLBIJJH_01507	1.56e-228	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NHLBIJJH_01508	0.0	-	1.11.1.5	-	P	ko:K00428	-	ko00000,ko01000	Di-haem cytochrome c peroxidase
NHLBIJJH_01509	2.48e-40	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
NHLBIJJH_01510	1.15e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
NHLBIJJH_01511	0.0	-	-	-	P	ko:K04759	-	ko00000,ko02000	Ferrous iron transport protein B C terminus
NHLBIJJH_01514	2.83e-303	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
NHLBIJJH_01516	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
NHLBIJJH_01517	9.94e-90	-	-	-	K	-	-	-	Helix-turn-helix diphteria tox regulatory element
NHLBIJJH_01518	7.56e-205	-	3.1.1.53	-	L	ko:K03547,ko:K05970	-	ko00000,ko01000,ko03400	3'-5' exonuclease activity
NHLBIJJH_01519	7.03e-134	-	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	SpoU rRNA Methylase family
NHLBIJJH_01520	0.0	-	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
NHLBIJJH_01521	9.37e-256	-	-	-	S	-	-	-	Glycoside-hydrolase family GH114
NHLBIJJH_01522	3.86e-304	-	-	-	M	-	-	-	Glycosyl transferases group 1
NHLBIJJH_01524	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RecQ zinc-binding
NHLBIJJH_01525	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
NHLBIJJH_01526	8.66e-227	-	-	-	-	-	-	-	-
NHLBIJJH_01527	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
NHLBIJJH_01528	1.87e-248	-	-	-	-	-	-	-	-
NHLBIJJH_01529	3e-250	rgpB	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NHLBIJJH_01530	0.0	ahcY	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NHLBIJJH_01531	3.77e-291	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NHLBIJJH_01532	1.36e-214	-	-	-	KQ	-	-	-	Hypothetical methyltransferase
NHLBIJJH_01535	0.0	-	-	-	E	-	-	-	PFAM major facilitator superfamily MFS_1
NHLBIJJH_01536	3.17e-206	-	-	-	G	ko:K06867,ko:K07001	-	ko00000	response to abiotic stimulus
NHLBIJJH_01538	5.24e-296	-	-	-	MU	ko:K15725	-	ko00000,ko02000	efflux transmembrane transporter activity
NHLBIJJH_01539	6.53e-296	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHLBIJJH_01540	0.0	-	-	-	P	ko:K07239	-	ko00000	AcrB/AcrD/AcrF family
NHLBIJJH_01541	1.46e-147	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHLBIJJH_01542	2.38e-169	-	-	-	CO	-	-	-	Protein conserved in bacteria
NHLBIJJH_01543	2.6e-231	-	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
NHLBIJJH_01544	5.9e-156	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
NHLBIJJH_01545	0.0	-	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Surface antigen
NHLBIJJH_01546	8.38e-282	tig	-	-	O	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NHLBIJJH_01547	2.5e-153	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHLBIJJH_01548	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NHLBIJJH_01549	2.49e-256	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NHLBIJJH_01551	9.94e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHLBIJJH_01553	3.61e-46	-	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecE/Sec61-gamma subunits of protein translocation complex
NHLBIJJH_01554	6.29e-135	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
NHLBIJJH_01555	2.58e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NHLBIJJH_01556	1.74e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NHLBIJJH_01557	9.92e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NHLBIJJH_01558	3.69e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NHLBIJJH_01560	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHLBIJJH_01562	3.39e-31	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NHLBIJJH_01563	1.68e-118	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NHLBIJJH_01564	4.91e-59	cas4	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	crispr-associated protein cas4
NHLBIJJH_01565	1.52e-85	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	DEAD-like helicases superfamily
NHLBIJJH_01566	8.52e-108	-	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
NHLBIJJH_01567	1.29e-133	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
NHLBIJJH_01568	1.07e-116	csd2	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein, Csd2 family
NHLBIJJH_01569	3.29e-280	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
NHLBIJJH_01571	0.0	-	1.2.1.88, 1.5.5.2	-	CE	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko03000	Proline dehydrogenase
NHLBIJJH_01573	1.01e-45	-	-	-	S	-	-	-	R3H domain
NHLBIJJH_01574	0.0	-	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Catalase
NHLBIJJH_01576	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
NHLBIJJH_01577	2.19e-136	rbr	-	-	C	-	-	-	Rubrerythrin
NHLBIJJH_01578	1.79e-143	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NHLBIJJH_01580	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk_gamma
NHLBIJJH_01581	4e-180	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	polysaccharide export
NHLBIJJH_01582	0.0	gumC	-	-	DM	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	PFAM lipopolysaccharide biosynthesis protein
NHLBIJJH_01583	9.48e-165	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	protein tyrosine phosphatase activity
NHLBIJJH_01584	4.63e-174	-	-	-	M	-	-	-	Bacterial sugar transferase
NHLBIJJH_01585	9.83e-189	wbyL	-	GT2	M	ko:K13002	-	ko00000,ko01000,ko01003,ko01005	transferase activity, transferring glycosyl groups
NHLBIJJH_01586	2.98e-292	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NHLBIJJH_01587	2.84e-285	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NHLBIJJH_01588	9.22e-290	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
NHLBIJJH_01589	2.43e-241	-	-	-	-	-	-	-	-
NHLBIJJH_01590	1.77e-261	-	-	-	M	ko:K02847,ko:K13009	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
NHLBIJJH_01591	2.52e-200	-	-	-	S	-	-	-	Glycosyl transferase family 11
NHLBIJJH_01592	1.48e-246	-	-	-	M	-	-	-	Glycosyl transferases group 1
NHLBIJJH_01593	4.3e-278	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
NHLBIJJH_01594	1.63e-279	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NHLBIJJH_01595	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_01596	2.67e-113	-	-	-	S	ko:K03818	-	ko00000,ko01000	maltose O-acetyltransferase activity
NHLBIJJH_01597	1.65e-208	-	-	-	M	-	-	-	PFAM glycosyl transferase family 2
NHLBIJJH_01598	1.07e-237	-	-	-	M	-	-	-	Glycosyl transferase, family 2
NHLBIJJH_01599	1.58e-25	-	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
NHLBIJJH_01600	1.26e-122	-	-	-	C	-	-	-	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NHLBIJJH_01601	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
NHLBIJJH_01602	2.21e-230	-	-	-	C	-	-	-	Nitroreductase family
NHLBIJJH_01603	0.0	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
NHLBIJJH_01605	8.77e-284	-	-	-	S	-	-	-	very-long-chain-acyl-CoA dehydrogenase activity
NHLBIJJH_01606	2.93e-93	-	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
NHLBIJJH_01607	1.83e-301	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
NHLBIJJH_01608	0.0	-	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
NHLBIJJH_01609	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NHLBIJJH_01611	2.11e-314	-	1.1.1.40	-	C	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Malic enzyme, NAD binding domain
NHLBIJJH_01612	0.0	-	-	-	I	ko:K06889,ko:K09914	-	ko00000	PFAM Prenyltransferase squalene oxidase
NHLBIJJH_01613	4.86e-230	exsH	3.2.1.178, 3.2.1.18, 3.2.1.52	GH16,GH20,GH33	G	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	xyloglucan:xyloglucosyl transferase activity
NHLBIJJH_01614	5.04e-257	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
NHLBIJJH_01615	2.76e-129	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NHLBIJJH_01616	3.06e-157	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NHLBIJJH_01617	0.0	yidC	-	-	O	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	serine-type endopeptidase activity
NHLBIJJH_01618	1.53e-266	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
NHLBIJJH_01624	7.48e-19	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
NHLBIJJH_01626	1.43e-309	-	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Seryl-tRNA synthetase N-terminal domain
NHLBIJJH_01627	5.79e-274	-	-	-	E	-	-	-	Alcohol dehydrogenase GroES-like domain
NHLBIJJH_01629	1e-215	-	3.5.1.53	-	K	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
NHLBIJJH_01630	1.33e-231	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NHLBIJJH_01631	6.5e-215	-	-	-	S	-	-	-	Protein of unknown function DUF58
NHLBIJJH_01632	2.52e-138	-	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	Peptidyl-tRNA hydrolase
NHLBIJJH_01633	0.0	-	-	-	M	-	-	-	Transglycosylase
NHLBIJJH_01634	0.0	-	3.4.24.3	-	NU	ko:K01387	-	ko00000,ko01000,ko01002,ko02042	translation initiation factor activity
NHLBIJJH_01635	0.0	-	-	-	H	-	-	-	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHLBIJJH_01636	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHLBIJJH_01639	0.0	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
NHLBIJJH_01640	2.95e-299	-	1.12.99.6	-	C	ko:K06282	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	NiFe/NiFeSe hydrogenase small subunit C-terminal
NHLBIJJH_01641	0.0	-	1.12.99.6	-	C	ko:K06281	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nickel-dependent hydrogenase
NHLBIJJH_01642	1.12e-290	hyaC	-	-	C	ko:K03620	ko02020,map02020	ko00000,ko00001	Prokaryotic cytochrome b561
NHLBIJJH_01643	3.4e-126	-	-	-	C	ko:K03605	-	ko00000,ko01000,ko01002	Hydrogenase maturation protease
NHLBIJJH_01644	2.09e-76	-	-	-	C	ko:K04651	-	ko00000,ko03110	Hydrogenase/urease nickel incorporation, metallochaperone, hypA
NHLBIJJH_01646	1.37e-86	-	-	-	S	ko:K09940	-	ko00000	Domain of unknown function (DUF4870)
NHLBIJJH_01647	1.24e-179	-	-	-	M	-	-	-	NLP P60 protein
NHLBIJJH_01648	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, domain 2
NHLBIJJH_01649	2.42e-154	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
NHLBIJJH_01650	5.93e-261	-	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
NHLBIJJH_01654	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NHLBIJJH_01655	2.57e-251	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
NHLBIJJH_01656	0.0	-	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
NHLBIJJH_01658	3.08e-107	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
NHLBIJJH_01660	0.0	-	3.2.1.52	GH20	G	ko:K01207,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko01501,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map01501,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
NHLBIJJH_01661	2.18e-302	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHLBIJJH_01662	3.4e-227	-	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate synthetase A protein
NHLBIJJH_01663	1.18e-253	-	-	-	S	-	-	-	Putative S-adenosyl-L-methionine-dependent methyltransferase
NHLBIJJH_01665	5.88e-277	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
NHLBIJJH_01666	1.58e-239	-	-	-	O	-	-	-	Trypsin-like peptidase domain
NHLBIJJH_01667	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Transglycosylase
NHLBIJJH_01668	9.93e-285	-	-	-	S	ko:K09760	-	ko00000	RmuC family
NHLBIJJH_01669	8.08e-171	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
NHLBIJJH_01670	1.25e-132	-	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NHLBIJJH_01671	3.08e-207	-	-	-	S	-	-	-	RDD family
NHLBIJJH_01672	0.0	-	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MacB-like periplasmic core domain
NHLBIJJH_01673	3.39e-210	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
NHLBIJJH_01674	6.5e-90	-	-	-	S	ko:K09793	-	ko00000	Protein of unknown function (DUF456)
NHLBIJJH_01675	1.13e-56	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NHLBIJJH_01676	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
NHLBIJJH_01677	4.3e-255	-	-	-	S	-	-	-	Peptidase family M28
NHLBIJJH_01678	3.85e-237	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NHLBIJJH_01679	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHLBIJJH_01680	3.41e-184	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase (SPase) II
NHLBIJJH_01681	9.37e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
NHLBIJJH_01682	1.05e-112	-	-	-	P	-	-	-	Rhodanese-like domain
NHLBIJJH_01683	5.22e-296	-	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NHLBIJJH_01684	0.0	-	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NHLBIJJH_01685	0.000231	-	2.7.11.1, 2.7.11.17	-	T	ko:K08794,ko:K13412,ko:K17530	ko04626,ko04921,ko04925,ko05145,map04626,map04921,map04925,map05145	ko00000,ko00001,ko01000,ko01001	protein serine/threonine kinase activity
NHLBIJJH_01687	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NHLBIJJH_01688	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
NHLBIJJH_01689	2.9e-100	-	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Glyoxalase-like domain
NHLBIJJH_01690	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
NHLBIJJH_01692	1.97e-54	-	-	-	I	-	-	-	PFAM biotin lipoyl attachment domain-containing protein
NHLBIJJH_01693	0.0	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
NHLBIJJH_01694	1.11e-190	-	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
NHLBIJJH_01695	0.0	-	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
NHLBIJJH_01697	3.88e-205	-	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NHLBIJJH_01698	7.56e-271	-	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
NHLBIJJH_01699	1.13e-228	-	2.7.1.11	-	G	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Phosphofructokinase
NHLBIJJH_01700	2.72e-183	-	-	-	L	ko:K10800	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	uracil-dna glycosylase
NHLBIJJH_01701	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHLBIJJH_01702	0.0	poxB	1.2.3.3, 1.2.5.1	-	EH	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
NHLBIJJH_01705	3.18e-237	-	-	-	F	-	-	-	helicase superfamily c-terminal domain
NHLBIJJH_01706	2.96e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF1837)
NHLBIJJH_01707	1.48e-67	-	-	-	S	-	-	-	Type II restriction endonuclease EcoO109I
NHLBIJJH_01708	1.11e-167	dcm	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NHLBIJJH_01709	1.4e-27	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NHLBIJJH_01710	5.93e-61	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	DNA mismatch endonuclease Vsr
NHLBIJJH_01711	1.16e-165	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NHLBIJJH_01712	7.02e-27	-	-	-	D	-	-	-	Plasmid recombination enzyme
NHLBIJJH_01713	3.36e-40	-	-	-	L	-	-	-	Domain of unknown function (DUF4368)
NHLBIJJH_01714	0.0	-	-	-	G	-	-	-	alpha-galactosidase
NHLBIJJH_01716	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
NHLBIJJH_01717	2.76e-267	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHLBIJJH_01718	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NHLBIJJH_01719	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
NHLBIJJH_01721	1.74e-177	-	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NHLBIJJH_01723	4.39e-165	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
NHLBIJJH_01726	0.0	-	-	-	L	-	-	-	DNA restriction-modification system
NHLBIJJH_01730	3.92e-115	-	-	-	-	-	-	-	-
NHLBIJJH_01731	6.34e-182	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
NHLBIJJH_01733	5.46e-161	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHLBIJJH_01734	2.04e-258	tdh	1.1.1.103	-	E	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
NHLBIJJH_01735	0.0	-	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Carbohydrate phosphorylase
NHLBIJJH_01736	4.82e-179	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
NHLBIJJH_01737	1.81e-82	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	ArsC family
NHLBIJJH_01738	0.0	-	-	-	J	ko:K07576	-	ko00000	Beta-Casp domain
NHLBIJJH_01740	1.16e-53	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NHLBIJJH_01741	1.52e-240	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
NHLBIJJH_01742	1.84e-237	-	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
NHLBIJJH_01743	2.05e-28	-	-	-	-	-	-	-	-
NHLBIJJH_01744	8.07e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	tRNA (Guanine-1)-methyltransferase
NHLBIJJH_01745	7.23e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NHLBIJJH_01746	1.66e-87	-	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
NHLBIJJH_01747	0.0	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
NHLBIJJH_01748	4.95e-134	-	-	-	C	-	-	-	Nitroreductase family
NHLBIJJH_01749	1.23e-110	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
NHLBIJJH_01754	7.29e-211	-	-	-	M	-	-	-	Peptidase family M23
NHLBIJJH_01755	3.4e-227	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
NHLBIJJH_01756	4.13e-183	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NHLBIJJH_01757	4.21e-121	-	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NHLBIJJH_01758	1.69e-174	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate reductase, N-terminus
NHLBIJJH_01759	1.02e-203	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
NHLBIJJH_01762	9e-255	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Iron-containing alcohol dehydrogenase
NHLBIJJH_01764	1.41e-300	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NHLBIJJH_01765	6.18e-180	-	-	-	C	-	-	-	Cytochrome c7 and related cytochrome c
NHLBIJJH_01766	0.0	-	-	-	C	ko:K00184	-	ko00000	4Fe-4S dicluster domain
NHLBIJJH_01768	0.0	-	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	RecG wedge domain
NHLBIJJH_01769	1.64e-165	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
NHLBIJJH_01770	0.0	pckG	4.1.1.32	-	C	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
NHLBIJJH_01772	9.05e-85	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	4'-phosphopantetheinyl transferase superfamily
NHLBIJJH_01773	5.64e-173	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NHLBIJJH_01774	0.0	-	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT/IMPCHase bienzyme
NHLBIJJH_01775	4.34e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L9, N-terminal domain
NHLBIJJH_01776	1.05e-226	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NHLBIJJH_01777	2.63e-208	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
NHLBIJJH_01778	2.84e-18	-	-	-	S	-	-	-	Lipocalin-like
NHLBIJJH_01780	8.77e-239	cbiM	-	-	P	ko:K02007,ko:K02009,ko:K16915	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt ion transport
NHLBIJJH_01781	2.42e-195	cbiQ	-	-	P	ko:K02007,ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transmembrane transporter activity
NHLBIJJH_01782	4.82e-179	cbiO	-	-	P	ko:K02006,ko:K02008,ko:K16784,ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase activity
NHLBIJJH_01783	0.0	-	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	HELICc2
NHLBIJJH_01785	4.94e-210	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
NHLBIJJH_01786	0.0	-	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	TopoisomeraseII
NHLBIJJH_01787	6.14e-173	-	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHLBIJJH_01788	2.41e-259	-	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
NHLBIJJH_01789	2.13e-96	-	-	-	L	ko:K07447	-	ko00000,ko01000	Likely ribonuclease with RNase H fold.
NHLBIJJH_01790	3.85e-235	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
NHLBIJJH_01791	1.45e-55	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
NHLBIJJH_01792	1.04e-49	-	-	-	-	-	-	-	-
NHLBIJJH_01793	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha galactosidase A
NHLBIJJH_01794	1.27e-219	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NHLBIJJH_01795	0.0	-	-	-	E	-	-	-	Aminotransferase class I and II
NHLBIJJH_01796	4.6e-305	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHLBIJJH_01797	1.04e-78	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
NHLBIJJH_01798	0.0	-	-	-	P	-	-	-	Sulfatase
NHLBIJJH_01800	9.64e-153	-	-	-	K	-	-	-	Transcriptional regulator
NHLBIJJH_01801	2.5e-190	-	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
NHLBIJJH_01802	1.35e-236	-	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NHLBIJJH_01803	1.03e-121	-	-	-	M	ko:K03098	-	ko00000,ko04147	Lipocalin-like domain
NHLBIJJH_01804	1.58e-205	-	-	-	S	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
NHLBIJJH_01805	5.75e-202	-	-	-	O	-	-	-	stress-induced mitochondrial fusion
NHLBIJJH_01807	3.3e-239	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NHLBIJJH_01809	1.73e-295	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
NHLBIJJH_01810	1.49e-237	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
NHLBIJJH_01811	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_01812	1.78e-241	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
NHLBIJJH_01813	0.0	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
NHLBIJJH_01814	7.83e-206	-	-	-	S	-	-	-	Protein of unknown function DUF58
NHLBIJJH_01815	0.0	-	-	-	S	-	-	-	Aerotolerance regulator N-terminal
NHLBIJJH_01816	0.0	-	-	-	S	-	-	-	von Willebrand factor type A domain
NHLBIJJH_01817	3.43e-291	-	-	-	-	-	-	-	-
NHLBIJJH_01818	1.35e-257	-	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
NHLBIJJH_01819	6.71e-90	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
NHLBIJJH_01820	1.02e-282	-	-	-	C	-	-	-	Aldo/keto reductase family
NHLBIJJH_01821	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
NHLBIJJH_01822	9.96e-141	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
NHLBIJJH_01823	1.19e-195	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
NHLBIJJH_01825	7.48e-235	-	2.7.11.1	-	T	ko:K08884,ko:K12132,ko:K20333	ko02024,map02024	ko00000,ko00001,ko01000,ko01001	PFAM Formylglycine-generating sulfatase enzyme
NHLBIJJH_01827	1.11e-262	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
NHLBIJJH_01828	2.54e-132	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NHLBIJJH_01829	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NHLBIJJH_01830	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NHLBIJJH_01831	1.05e-41	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_01835	5.51e-133	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_01837	1.85e-102	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_01845	2.95e-314	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_01847	1.56e-144	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_01851	1.89e-80	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_01853	6.59e-90	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_01854	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
NHLBIJJH_01855	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
NHLBIJJH_01856	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
NHLBIJJH_01857	2.94e-131	-	-	-	-	-	-	-	-
NHLBIJJH_01858	2.36e-245	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
NHLBIJJH_01861	1.27e-180	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyrroline-5-carboxylate reductase dimerisation
NHLBIJJH_01862	4.69e-159	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
NHLBIJJH_01863	5.51e-211	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
NHLBIJJH_01864	1.33e-226	-	-	-	S	-	-	-	Protein conserved in bacteria
NHLBIJJH_01865	2.01e-34	-	-	-	KLT	-	-	-	Tyrosine-protein kinase, subgroup, catalytic domain
NHLBIJJH_01866	0.0	-	4.1.99.1	-	E	ko:K01667	ko00380,map00380	ko00000,ko00001,ko01000	Beta-eliminating lyase
NHLBIJJH_01867	6.76e-143	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
NHLBIJJH_01868	7.12e-255	-	-	-	S	-	-	-	Domain of unknown function (DUF4105)
NHLBIJJH_01869	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	B3/4 domain
NHLBIJJH_01870	2.34e-240	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Aminoacyl tRNA synthetase class II, N-terminal domain
NHLBIJJH_01871	4.72e-285	-	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
NHLBIJJH_01872	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
NHLBIJJH_01873	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Hsp90 protein
NHLBIJJH_01874	6.97e-174	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
NHLBIJJH_01875	3.94e-273	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHLBIJJH_01876	2.55e-102	-	-	-	K	-	-	-	Transcriptional regulator
NHLBIJJH_01877	1.67e-309	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
NHLBIJJH_01878	4.56e-215	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
NHLBIJJH_01879	8.4e-136	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K00788,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NHLBIJJH_01880	1.15e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NHLBIJJH_01881	2.47e-116	gepA	-	-	K	-	-	-	Phage-associated protein
NHLBIJJH_01883	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
NHLBIJJH_01884	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
NHLBIJJH_01885	1.21e-241	-	-	-	E	ko:K07588	-	ko00000,ko01000	ArgK protein
NHLBIJJH_01886	1.56e-113	-	-	-	F	ko:K08311	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	NUDIX domain
NHLBIJJH_01887	0.0	sepA	-	-	Q	-	-	-	COG2015, Alkyl sulfatase and related hydrolases
NHLBIJJH_01888	6.95e-122	-	-	-	-	-	-	-	-
NHLBIJJH_01889	4.91e-110	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NHLBIJJH_01890	1.48e-291	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
NHLBIJJH_01891	8.17e-159	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
NHLBIJJH_01892	1.25e-240	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase
NHLBIJJH_01894	3.41e-107	-	-	-	K	-	-	-	DNA-binding transcription factor activity
NHLBIJJH_01895	4.2e-264	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Biotin-lipoyl like
NHLBIJJH_01896	0.0	-	-	-	V	-	-	-	AcrB/AcrD/AcrF family
NHLBIJJH_01897	6.85e-113	-	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Dihydrofolate reductase
NHLBIJJH_01898	5.77e-208	-	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Thymidylate synthase
NHLBIJJH_01899	0.0	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phospholipase D. Active site motifs.
NHLBIJJH_01900	0.0	-	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	HMGL-like
NHLBIJJH_01902	0.0	-	-	-	V	ko:K03327	-	ko00000,ko02000	MatE
NHLBIJJH_01903	6.11e-256	-	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Iron-sulfur cluster assembly protein
NHLBIJJH_01904	6.78e-42	-	-	-	S	-	-	-	PurA ssDNA and RNA-binding protein
NHLBIJJH_01906	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	LeuA allosteric (dimerisation) domain
NHLBIJJH_01907	0.0	prlC	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
NHLBIJJH_01908	3.88e-283	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHLBIJJH_01909	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NHLBIJJH_01910	0.0	-	-	-	MU	ko:K18139	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Outer membrane efflux protein
NHLBIJJH_01912	0.0	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NHLBIJJH_01913	1.59e-150	-	-	-	-	-	-	-	-
NHLBIJJH_01915	1.34e-109	ptsN	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
NHLBIJJH_01916	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
NHLBIJJH_01917	2.47e-253	-	-	-	L	-	-	-	Transposase IS200 like
NHLBIJJH_01918	0.0	-	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
NHLBIJJH_01919	6.77e-269	-	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NHLBIJJH_01920	3.89e-149	dedA	-	-	S	-	-	-	FtsZ-dependent cytokinesis
NHLBIJJH_01921	6.7e-119	-	-	-	S	-	-	-	nitrogen fixation
NHLBIJJH_01922	6.22e-74	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NHLBIJJH_01923	1.75e-75	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NHLBIJJH_01924	3.21e-115	-	-	-	CO	-	-	-	cell redox homeostasis
NHLBIJJH_01926	8.64e-180	-	-	-	-	-	-	-	-
NHLBIJJH_01928	0.0	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
NHLBIJJH_01930	3.45e-145	-	-	-	-	-	-	-	-
NHLBIJJH_01931	1.84e-63	-	-	-	K	-	-	-	DNA-binding transcription factor activity
NHLBIJJH_01933	0.0	-	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	C-terminal, D2-small domain, of ClpB protein
NHLBIJJH_01935	1.29e-230	-	-	-	K	-	-	-	DNA-binding transcription factor activity
NHLBIJJH_01936	1.76e-79	-	-	-	S	-	-	-	PFAM Cupin 2 conserved barrel domain protein
NHLBIJJH_01937	9.61e-131	-	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NHLBIJJH_01938	0.0	-	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NHLBIJJH_01939	0.0	-	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NHLBIJJH_01941	2.4e-167	-	-	-	T	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
NHLBIJJH_01942	0.0	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
NHLBIJJH_01945	1.67e-05	-	-	-	-	-	-	-	-
NHLBIJJH_01946	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
NHLBIJJH_01947	1.78e-266	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2219)
NHLBIJJH_01948	2.53e-202	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
NHLBIJJH_01949	2.63e-84	-	-	-	M	-	-	-	Lysin motif
NHLBIJJH_01950	1.45e-178	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NHLBIJJH_01951	0.0	-	-	-	V	-	-	-	MatE
NHLBIJJH_01952	1.05e-252	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
NHLBIJJH_01954	8.38e-258	-	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NHLBIJJH_01956	2.76e-129	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
NHLBIJJH_01957	3.07e-264	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	RibD C-terminal domain
NHLBIJJH_01959	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NHLBIJJH_01960	4.27e-273	-	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
NHLBIJJH_01961	0.0	-	-	-	O	-	-	-	Trypsin
NHLBIJJH_01962	7.97e-108	-	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
NHLBIJJH_01963	0.0	-	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Oligonucleotide/oligosaccharide-binding (OB)-fold
NHLBIJJH_01964	3.52e-161	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
NHLBIJJH_01965	0.0	-	-	-	P	-	-	-	Cation transport protein
NHLBIJJH_01967	2.58e-178	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NHLBIJJH_01968	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
NHLBIJJH_01969	3.2e-70	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NHLBIJJH_01970	1.32e-101	manC	-	-	S	-	-	-	Cupin domain
NHLBIJJH_01971	0.0	-	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NHLBIJJH_01972	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
NHLBIJJH_01973	1.02e-187	pppL	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	protein serine/threonine phosphatase activity
NHLBIJJH_01974	4.34e-152	-	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Glycerol-3-phosphate acyltransferase
NHLBIJJH_01975	8.08e-236	gpsA	1.1.1.94	-	C	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NHLBIJJH_01976	8.62e-102	-	-	-	-	-	-	-	-
NHLBIJJH_01978	6.95e-264	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
NHLBIJJH_01979	1.32e-313	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
NHLBIJJH_01980	0.0	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
NHLBIJJH_01981	6.7e-05	-	-	-	-	-	-	-	-
NHLBIJJH_01982	0.0	-	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
NHLBIJJH_01983	1.21e-210	-	-	-	S	-	-	-	Rhomboid family
NHLBIJJH_01984	2.94e-266	-	-	-	E	-	-	-	FAD dependent oxidoreductase
NHLBIJJH_01985	2.64e-267	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NHLBIJJH_01989	2.23e-138	-	2.1.1.113	-	L	ko:K00590	-	ko00000,ko01000,ko02048	DNA methylase
NHLBIJJH_01994	2.12e-51	-	-	-	S	-	-	-	AAA domain
NHLBIJJH_01999	1.59e-97	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NHLBIJJH_02000	1.48e-71	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
NHLBIJJH_02002	1.84e-136	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
NHLBIJJH_02006	1.11e-09	-	-	-	-	-	-	-	-
NHLBIJJH_02008	0.0	-	-	-	G	-	-	-	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain
NHLBIJJH_02009	0.000969	-	-	-	-	-	-	-	-
NHLBIJJH_02010	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
NHLBIJJH_02011	5.46e-189	-	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
NHLBIJJH_02013	0.0	-	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	DHHA2
NHLBIJJH_02014	2.68e-253	-	-	-	N	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease Exonuclease Phosphatase
NHLBIJJH_02015	8.25e-63	-	-	-	L	ko:K09747	-	ko00000	YbaB/EbfC DNA-binding family
NHLBIJJH_02016	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHLBIJJH_02018	4.03e-174	-	-	-	D	-	-	-	Phage-related minor tail protein
NHLBIJJH_02020	6.86e-174	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
NHLBIJJH_02021	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHLBIJJH_02022	6.12e-40	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NHLBIJJH_02023	2.79e-97	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NHLBIJJH_02024	1.95e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S9/S16
NHLBIJJH_02025	1.27e-99	-	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Predicted SPOUT methyltransferase
NHLBIJJH_02026	0.0	-	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NHLBIJJH_02027	1.49e-181	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
NHLBIJJH_02028	1.08e-97	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
NHLBIJJH_02029	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
NHLBIJJH_02030	0.0	-	-	-	M	-	-	-	PFAM glycosyl transferase family 51
NHLBIJJH_02031	1.67e-181	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
NHLBIJJH_02032	1.3e-115	ispF	4.6.1.12	-	I	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NHLBIJJH_02033	1.06e-180	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
NHLBIJJH_02034	3.98e-228	-	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphomannose isomerase type I
NHLBIJJH_02035	1.11e-236	-	-	-	-	-	-	-	-
NHLBIJJH_02036	8.37e-296	-	-	-	C	-	-	-	Na+/H+ antiporter family
NHLBIJJH_02037	1.03e-265	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
NHLBIJJH_02038	6.96e-265	-	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
NHLBIJJH_02040	1.88e-273	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase small chain, CPSase domain
NHLBIJJH_02041	0.0	-	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
NHLBIJJH_02042	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NHLBIJJH_02043	0.0	-	1.4.1.13, 1.4.1.14	-	E	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
NHLBIJJH_02044	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
NHLBIJJH_02045	4.61e-61	-	-	-	S	ko:K08998	-	ko00000	Haemolytic
NHLBIJJH_02046	4.9e-76	-	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	Ribonuclease P
NHLBIJJH_02047	1.1e-34	-	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
NHLBIJJH_02048	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NHLBIJJH_02049	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NHLBIJJH_02050	0.0	-	-	-	G	-	-	-	Trehalase
NHLBIJJH_02051	4.06e-210	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
NHLBIJJH_02052	3.45e-157	-	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
NHLBIJJH_02053	1.19e-199	-	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
NHLBIJJH_02054	2.63e-208	-	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Polyprenyl synthetase
NHLBIJJH_02055	3.89e-241	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NHLBIJJH_02057	5.5e-176	-	-	-	-	-	-	-	-
NHLBIJJH_02058	0.0	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
NHLBIJJH_02059	2.91e-220	-	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
NHLBIJJH_02060	1.74e-107	-	-	-	E	ko:K00612	-	ko00000,ko01000	lipolytic protein G-D-S-L family
NHLBIJJH_02061	1.14e-134	panZ	-	-	K	-	-	-	-acetyltransferase
NHLBIJJH_02067	5.71e-166	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
NHLBIJJH_02068	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
NHLBIJJH_02069	2.09e-207	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
NHLBIJJH_02070	4.97e-272	-	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
NHLBIJJH_02071	4.4e-138	-	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NHLBIJJH_02072	1.05e-188	-	5.2.1.8	-	O	ko:K03773	-	ko00000,ko01000,ko03110	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
NHLBIJJH_02073	1.14e-148	-	-	-	IQ	-	-	-	RmlD substrate binding domain
NHLBIJJH_02074	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GcpE protein
NHLBIJJH_02075	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
NHLBIJJH_02076	8.75e-198	-	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NHLBIJJH_02077	3.32e-119	-	-	-	-	-	-	-	-
NHLBIJJH_02078	3.85e-194	-	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	CDP-alcohol phosphatidyltransferase
NHLBIJJH_02079	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NHLBIJJH_02080	1.13e-226	-	-	-	M	ko:K01993	-	ko00000	HlyD family secretion protein
NHLBIJJH_02081	0.0	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHLBIJJH_02082	1.03e-243	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NHLBIJJH_02083	1.07e-246	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NHLBIJJH_02086	6.7e-301	nupG	-	-	G	ko:K03289,ko:K03301,ko:K08218,ko:K11537	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
NHLBIJJH_02087	5.91e-259	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHLBIJJH_02088	4.86e-110	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07305,ko:K12267	-	ko00000,ko01000	peptide-methionine (R)-S-oxide reductase activity
NHLBIJJH_02089	3.9e-306	-	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NHLBIJJH_02091	3.08e-146	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHLBIJJH_02092	2.37e-46	-	-	-	J	-	-	-	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NHLBIJJH_02093	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_02094	0.0	-	-	-	S	-	-	-	Sodium:neurotransmitter symporter family
NHLBIJJH_02095	3.6e-152	-	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
NHLBIJJH_02096	1.21e-210	-	-	-	M	-	-	-	Mechanosensitive ion channel
NHLBIJJH_02097	4.62e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Amino acid kinase family
NHLBIJJH_02098	2.53e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NHLBIJJH_02099	9.17e-70	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
NHLBIJJH_02100	2.93e-102	-	-	-	K	-	-	-	DNA-binding transcription factor activity
NHLBIJJH_02101	1.44e-229	-	-	-	J	-	-	-	Belongs to the universal ribosomal protein uS2 family
NHLBIJJH_02102	3.4e-227	-	-	-	L	-	-	-	Elongator protein 3, MiaB family, Radical SAM
NHLBIJJH_02103	4.55e-124	-	-	-	C	-	-	-	Nitroreductase family
NHLBIJJH_02104	2.21e-105	-	-	-	EG	-	-	-	membrane
NHLBIJJH_02105	3.78e-23	-	-	-	C	-	-	-	Nitroreductase family
NHLBIJJH_02106	3.63e-65	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NHLBIJJH_02107	1.35e-152	-	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
NHLBIJJH_02108	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
NHLBIJJH_02110	7.65e-101	-	-	-	M	ko:K06077	-	ko00000	Glycine zipper 2TM domain
NHLBIJJH_02111	2.15e-234	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
NHLBIJJH_02112	2.57e-140	-	-	-	P	ko:K02039	-	ko00000	PhoU domain
NHLBIJJH_02113	2.22e-186	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHLBIJJH_02114	5.06e-220	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	PBP superfamily domain
NHLBIJJH_02115	0.0	pstC	-	-	P	ko:K02037,ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLBIJJH_02116	0.0	-	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLBIJJH_02117	8.04e-184	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHLBIJJH_02118	8.01e-153	phoU	-	-	P	ko:K02039	-	ko00000	negative regulation of phosphate transmembrane transport
NHLBIJJH_02120	5.44e-279	-	-	-	J	-	-	-	PFAM Endoribonuclease L-PSP
NHLBIJJH_02121	0.0	-	-	-	C	-	-	-	cytochrome C peroxidase
NHLBIJJH_02122	0.0	-	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
NHLBIJJH_02123	1.24e-297	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32
NHLBIJJH_02124	3.24e-148	-	-	-	C	-	-	-	lactate oxidation
NHLBIJJH_02125	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA Topoisomerase IV
NHLBIJJH_02126	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHLBIJJH_02127	5.27e-184	-	-	-	I	-	-	-	Acyl-ACP thioesterase
NHLBIJJH_02128	5.99e-231	-	4.1.1.35	-	M	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	3-beta hydroxysteroid dehydrogenase/isomerase family
NHLBIJJH_02129	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
NHLBIJJH_02130	2.04e-160	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
NHLBIJJH_02132	4.89e-237	-	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
NHLBIJJH_02134	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHLBIJJH_02135	1.15e-146	-	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NHLBIJJH_02136	4.34e-48	-	-	-	K	ko:K18566	ko00332,ko01130,map00332,map01130	ko00000,ko00001,ko01000	acetyltransferase
NHLBIJJH_02137	4.01e-301	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
NHLBIJJH_02138	3.02e-275	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
NHLBIJJH_02139	1.47e-121	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NHLBIJJH_02140	1.12e-63	-	-	-	J	-	-	-	RF-1 domain
NHLBIJJH_02141	3.94e-122	-	-	-	-	-	-	-	-
NHLBIJJH_02142	0.0	-	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP--glucose-1-phosphate uridylyltransferase
NHLBIJJH_02143	2.91e-183	-	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
NHLBIJJH_02145	3.41e-127	-	-	-	S	-	-	-	protein trimerization
NHLBIJJH_02146	2.72e-36	-	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
NHLBIJJH_02147	2.88e-63	tagD	2.7.7.39	-	H	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
NHLBIJJH_02148	1.17e-29	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	PFAM glycosyltransferase sugar-binding region containing DXD motif
NHLBIJJH_02149	4.46e-227	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
NHLBIJJH_02150	0.0	-	2.7.7.15	-	H	ko:K00968	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
NHLBIJJH_02151	4.35e-265	odh	1.5.1.28	-	I	ko:K04940	-	ko00000,ko01000	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NHLBIJJH_02152	0.0	cobD	2.6.1.9, 2.7.7.74, 4.1.1.81	-	M	ko:K00817,ko:K04720,ko:K07281	ko00340,ko00350,ko00360,ko00400,ko00401,ko00562,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00562,map00860,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	nucleotidyl transferase
NHLBIJJH_02153	1.45e-262	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
NHLBIJJH_02154	0.0	-	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha amylase, C-terminal all-beta domain
NHLBIJJH_02156	5.06e-94	-	-	-	S	ko:K02426	-	ko00000	Fe-S metabolism associated domain
NHLBIJJH_02157	1.64e-223	-	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NHLBIJJH_02158	0.0	-	-	-	P	-	-	-	Sulfatase
NHLBIJJH_02159	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHLBIJJH_02160	8.72e-53	-	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
NHLBIJJH_02161	3.12e-223	hprK	-	-	T	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
NHLBIJJH_02162	0.0	-	-	-	E	-	-	-	Peptidase dimerisation domain
NHLBIJJH_02163	8.83e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHLBIJJH_02164	1.17e-138	-	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
NHLBIJJH_02165	0.0	-	-	-	S	-	-	-	50S ribosome-binding GTPase
NHLBIJJH_02166	1.02e-163	-	-	-	S	ko:K06997	-	ko00000	Alanine racemase, N-terminal domain
NHLBIJJH_02167	1.88e-135	-	-	-	K	ko:K07735	-	ko00000,ko03000	Uncharacterized ACR, COG1678
NHLBIJJH_02168	3.51e-191	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
NHLBIJJH_02169	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
NHLBIJJH_02170	2.23e-204	-	-	-	-	-	-	-	-
NHLBIJJH_02171	3.45e-83	-	-	-	P	ko:K06195	-	ko00000	ApaG domain
NHLBIJJH_02172	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
NHLBIJJH_02173	8.26e-106	-	-	-	K	-	-	-	Lrp/AsnC ligand binding domain
NHLBIJJH_02174	3.2e-286	-	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
NHLBIJJH_02175	9.2e-208	-	-	-	S	-	-	-	CAAX protease self-immunity
NHLBIJJH_02176	8.72e-155	-	-	-	S	-	-	-	DUF218 domain
NHLBIJJH_02177	0.0	-	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Anticodon binding domain
NHLBIJJH_02178	1.16e-205	yeaE	-	-	S	-	-	-	aldo-keto reductase (NADP) activity
NHLBIJJH_02179	0.0	-	-	-	S	-	-	-	Oxygen tolerance
NHLBIJJH_02180	8.51e-42	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
NHLBIJJH_02182	6.21e-39	-	-	-	-	-	-	-	-
NHLBIJJH_02183	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHLBIJJH_02185	4e-234	-	-	-	CO	-	-	-	Thioredoxin-like
NHLBIJJH_02186	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
NHLBIJJH_02187	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
NHLBIJJH_02188	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
NHLBIJJH_02189	2.27e-75	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
NHLBIJJH_02190	5.74e-211	ybfH	-	-	EG	-	-	-	spore germination
NHLBIJJH_02191	9.28e-139	-	-	-	-	-	-	-	-
NHLBIJJH_02192	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
NHLBIJJH_02193	3.62e-121	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHLBIJJH_02194	7.48e-188	-	-	-	O	ko:K04083	-	ko00000,ko03110	Hsp33 protein
NHLBIJJH_02197	3.71e-236	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
NHLBIJJH_02201	1.69e-129	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
NHLBIJJH_02202	1.64e-175	-	4.2.99.20	-	I	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
NHLBIJJH_02203	1.46e-75	-	-	-	S	ko:K09954	-	ko00000	Putative quorum-sensing-regulated virulence factor
NHLBIJJH_02205	1.24e-51	-	-	-	-	-	-	-	-
NHLBIJJH_02206	4.89e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
NHLBIJJH_02207	1.96e-184	-	-	-	-	-	-	-	-
NHLBIJJH_02208	2.59e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
NHLBIJJH_02209	4.44e-110	-	-	-	KT	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
NHLBIJJH_02210	2.87e-305	-	-	-	C	-	-	-	4 iron, 4 sulfur cluster binding
NHLBIJJH_02211	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
NHLBIJJH_02212	2.67e-222	-	-	-	K	-	-	-	Transcriptional regulator
NHLBIJJH_02213	3.31e-175	-	-	-	C	-	-	-	aldo keto reductase
NHLBIJJH_02214	1.68e-185	-	-	-	S	-	-	-	Alpha/beta hydrolase family
NHLBIJJH_02215	1.44e-275	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
NHLBIJJH_02216	3.37e-309	-	-	-	C	-	-	-	Carboxymuconolactone decarboxylase family
NHLBIJJH_02217	1.2e-158	-	-	-	IQ	-	-	-	Short chain dehydrogenase
NHLBIJJH_02218	6.26e-149	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Psort location CytoplasmicMembrane, score
NHLBIJJH_02220	4.21e-137	-	-	-	J	ko:K05808	-	ko00000,ko03009	Sigma 54 modulation/S30EA ribosomal protein C terminus
NHLBIJJH_02222	2.17e-08	-	-	-	M	-	-	-	major outer membrane lipoprotein
NHLBIJJH_02223	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
NHLBIJJH_02225	2.57e-170	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
NHLBIJJH_02226	2.24e-307	-	-	-	C	-	-	-	Sulfatase-modifying factor enzyme 1
NHLBIJJH_02227	1.43e-11	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NHLBIJJH_02229	1.15e-05	-	-	-	-	-	-	-	-
NHLBIJJH_02231	8.72e-48	XK27_09985	-	-	S	-	-	-	Protein of unknown function (DUF1232)
NHLBIJJH_02232	1.43e-194	-	-	-	S	ko:K07051	-	ko00000	TatD related DNase
NHLBIJJH_02233	8.94e-56	-	-	-	-	-	-	-	-
NHLBIJJH_02234	4.83e-163	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	-
NHLBIJJH_02235	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
NHLBIJJH_02236	1.29e-187	-	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	2Fe-2S iron-sulfur cluster binding domain
NHLBIJJH_02238	1.55e-225	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
NHLBIJJH_02239	3.86e-261	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
NHLBIJJH_02240	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglucose isomerase
NHLBIJJH_02241	0.0	-	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Pyruvate phosphate dikinase, PEP/pyruvate binding domain
NHLBIJJH_02242	1.22e-143	aat	2.3.2.6	-	O	ko:K00684	-	ko00000,ko01000	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NHLBIJJH_02243	6.59e-256	-	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	endonuclease III
NHLBIJJH_02244	4.41e-218	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NHLBIJJH_02245	0.0	-	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
NHLBIJJH_02247	5.49e-181	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
NHLBIJJH_02248	1.12e-116	agmK	1.8.1.8	-	O	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	belongs to the thioredoxin family
NHLBIJJH_02249	3.57e-281	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
NHLBIJJH_02250	0.0	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
NHLBIJJH_02252	2.34e-108	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NHLBIJJH_02253	4.75e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
NHLBIJJH_02254	0.0	-	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	B12 binding domain
NHLBIJJH_02258	2.91e-114	-	-	-	S	ko:K03748	-	ko00000	DUF218 domain
NHLBIJJH_02260	2.79e-230	-	-	-	S	-	-	-	mannose-ethanolamine phosphotransferase activity
NHLBIJJH_02264	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RQC
NHLBIJJH_02266	3.7e-175	-	-	-	-	-	-	-	-
NHLBIJJH_02267	1.11e-208	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NHLBIJJH_02268	6.26e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NHLBIJJH_02269	1.55e-291	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NHLBIJJH_02270	1.57e-205	-	-	-	S	ko:K03453	-	ko00000	Bile acid
NHLBIJJH_02273	6.39e-71	-	-	-	-	-	-	-	-
NHLBIJJH_02274	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHLBIJJH_02275	0.0	-	2.3.1.40, 6.2.1.20	-	IQ	ko:K05939	ko00071,ko00564,map00071,map00564	ko00000,ko00001,ko01000	AMP-binding enzyme
NHLBIJJH_02276	3.49e-45	-	-	-	T	-	-	-	pathogenesis
NHLBIJJH_02278	1.69e-06	-	-	-	-	-	-	-	-
NHLBIJJH_02279	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
NHLBIJJH_02280	0.0	-	-	-	S	ko:K07126,ko:K13582	ko04112,map04112	ko00000,ko00001	beta-lactamase activity
NHLBIJJH_02281	1.38e-277	-	6.2.1.26	-	IQ	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	AMP-binding enzyme
NHLBIJJH_02282	1.27e-70	-	-	-	K	-	-	-	ribonuclease III activity
NHLBIJJH_02283	9.38e-166	-	-	-	-	-	-	-	-
NHLBIJJH_02284	8.56e-140	nuoC	1.6.5.3	-	C	ko:K00332	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NHLBIJJH_02285	6.52e-139	nuoB	1.6.5.3	-	C	ko:K00331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NHLBIJJH_02289	1.03e-107	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_02291	2.48e-21	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
NHLBIJJH_02296	1.88e-130	-	-	-	S	-	-	-	Glycosyl hydrolase 108
NHLBIJJH_02314	0.0	-	-	-	M	-	-	-	Psort location
NHLBIJJH_02315	4.42e-47	-	-	-	S	-	-	-	Domain of unknown function (DUF4315)
NHLBIJJH_02316	1.11e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF4366)
NHLBIJJH_02317	2.68e-43	-	-	-	-	-	-	-	-
NHLBIJJH_02318	3.67e-162	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NHLBIJJH_02319	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHLBIJJH_02320	7.52e-54	-	-	-	-	-	-	-	-
NHLBIJJH_02324	8.26e-134	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Serine dehydrogenase proteinase
NHLBIJJH_02325	1.37e-263	-	-	-	S	-	-	-	Phage portal protein, lambda family
NHLBIJJH_02326	1.56e-28	-	-	-	-	-	-	-	-
NHLBIJJH_02327	5.2e-309	-	-	-	S	-	-	-	Phage terminase large subunit (GpA)
NHLBIJJH_02328	4.46e-22	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
NHLBIJJH_02329	3.25e-47	-	-	-	-	-	-	-	-
NHLBIJJH_02330	3.56e-21	-	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHLBIJJH_02333	1.68e-28	-	-	-	S	-	-	-	COG NOG14118 non supervised orthologous group
NHLBIJJH_02334	2.77e-10	-	-	-	-	-	-	-	-
NHLBIJJH_02335	1.02e-09	-	-	-	-	-	-	-	-
NHLBIJJH_02336	1.3e-34	-	-	-	-	-	-	-	-
NHLBIJJH_02338	0.000692	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NHLBIJJH_02348	1.74e-84	-	-	-	K	-	-	-	DNA-templated transcription, initiation
NHLBIJJH_02349	1.57e-30	-	-	-	-	-	-	-	-
NHLBIJJH_02350	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
NHLBIJJH_02351	0.0	-	-	-	L	-	-	-	Domain of unknown function (DUF4368)
NHLBIJJH_02352	4.63e-40	-	-	-	L	-	-	-	Resolvase, N terminal domain
NHLBIJJH_02353	7.89e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
NHLBIJJH_02354	5.31e-68	-	-	-	-	-	-	-	-
NHLBIJJH_02355	3.25e-84	-	-	-	-	-	-	-	-
NHLBIJJH_02356	8.46e-82	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
NHLBIJJH_02357	1.35e-38	-	-	-	-	-	-	-	-
NHLBIJJH_02358	1.26e-60	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
NHLBIJJH_02359	1.54e-67	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NHLBIJJH_02362	7.78e-20	-	-	-	-	-	-	-	-
NHLBIJJH_02363	2.05e-06	-	-	-	L	-	-	-	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NHLBIJJH_02368	6.58e-46	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	COG COG3505 Type IV secretory pathway, VirD4 components
NHLBIJJH_02369	7.27e-42	-	-	-	S	-	-	-	Maff2 family
NHLBIJJH_02370	9.24e-189	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NHLBIJJH_02371	2.57e-109	-	-	-	S	-	-	-	PrgI family protein
NHLBIJJH_02372	2.86e-244	-	-	-	L	-	-	-	Phage integrase family
NHLBIJJH_02373	1.38e-250	-	-	-	L	-	-	-	Phage integrase family
NHLBIJJH_02374	7.98e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF3847)
NHLBIJJH_02376	7.86e-117	-	-	-	L	-	-	-	DNA replication protein
NHLBIJJH_02377	3.31e-210	-	-	-	L	-	-	-	Integrase core domain
NHLBIJJH_02380	1.31e-219	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
NHLBIJJH_02381	4.02e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3846)
NHLBIJJH_02382	7.1e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
NHLBIJJH_02383	2.08e-61	-	-	-	S	-	-	-	COG NOG20805 non supervised orthologous group
NHLBIJJH_02385	2.14e-197	-	-	-	-	-	-	-	-
NHLBIJJH_02386	1.77e-235	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
NHLBIJJH_02387	2.29e-285	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
NHLBIJJH_02388	1.07e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
NHLBIJJH_02389	0.0	-	-	-	-	-	-	-	-
NHLBIJJH_02390	1.55e-150	phoB	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator receiver domain protein
NHLBIJJH_02391	7.29e-137	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NHLBIJJH_02392	1.88e-42	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHLBIJJH_02393	1.5e-78	-	-	-	KL	-	-	-	SNF2 family N-terminal domain
NHLBIJJH_02394	6.29e-181	-	-	-	L	-	-	-	Protein of unknown function (DUF3849)
NHLBIJJH_02395	1.41e-70	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
NHLBIJJH_02396	1.86e-184	-	-	-	L	-	-	-	Transposase, mutator
NHLBIJJH_02398	4.69e-261	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
NHLBIJJH_02399	2.35e-99	-	-	-	L	-	-	-	CHC2 zinc finger
NHLBIJJH_02400	1.83e-152	-	-	-	S	-	-	-	Virulence-associated protein E
NHLBIJJH_02401	5.8e-29	-	-	-	-	-	-	-	-
NHLBIJJH_02402	4e-83	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
NHLBIJJH_02403	1e-78	-	-	-	S	-	-	-	Phage head-tail joining protein
NHLBIJJH_02404	9.17e-59	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NHLBIJJH_02405	1.35e-68	-	-	-	S	-	-	-	Phage capsid family
NHLBIJJH_02406	1.03e-162	-	-	-	S	-	-	-	AIG2-like family
NHLBIJJH_02407	2.4e-54	-	-	-	S	-	-	-	Domain of unknown function (DUF4314)
NHLBIJJH_02409	1.28e-103	-	-	-	-	-	-	-	-
NHLBIJJH_02412	1.72e-47	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Serine dehydrogenase proteinase
NHLBIJJH_02415	9.24e-116	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate ABC transporter
NHLBIJJH_02417	2.5e-39	-	-	-	-	-	-	-	-
NHLBIJJH_02418	3.38e-38	-	-	-	-	-	-	-	-
NHLBIJJH_02419	1.04e-180	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
NHLBIJJH_02421	7.95e-142	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain