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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
LEOIKIBE_00001	0.0	-	-	-	CO	-	-	-	Thioredoxin-like
LEOIKIBE_00006	1.17e-116	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LEOIKIBE_00007	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
LEOIKIBE_00008	1.22e-246	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LEOIKIBE_00009	2.73e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
LEOIKIBE_00010	4.98e-117	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
LEOIKIBE_00011	6.98e-80	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
LEOIKIBE_00012	2.96e-242	-	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LEOIKIBE_00013	3.13e-128	aroK	2.7.1.71	-	E	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LEOIKIBE_00014	9.56e-51	-	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S16
LEOIKIBE_00018	6.5e-215	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
LEOIKIBE_00019	1.53e-184	-	-	-	DTZ	-	-	-	EF-hand, calcium binding motif
LEOIKIBE_00020	5.64e-66	-	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
LEOIKIBE_00021	1.39e-282	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LEOIKIBE_00022	4.08e-149	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Putative methyltransferase
LEOIKIBE_00023	1.45e-172	-	-	-	F	-	-	-	NUDIX domain
LEOIKIBE_00024	8.14e-125	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
LEOIKIBE_00025	5.72e-206	-	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
LEOIKIBE_00026	1.9e-62	-	-	-	L	-	-	-	bacterial (prokaryotic) histone like domain
LEOIKIBE_00032	1.43e-142	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
LEOIKIBE_00033	2.38e-167	-	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LEOIKIBE_00034	3.33e-254	-	5.2.1.8	-	O	ko:K03771	-	ko00000,ko01000,ko03110	SurA N-terminal domain
LEOIKIBE_00035	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
LEOIKIBE_00036	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LEOIKIBE_00037	3.58e-202	-	-	-	-	-	-	-	-
LEOIKIBE_00038	6.79e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LEOIKIBE_00039	2.19e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LEOIKIBE_00040	2.36e-34	-	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L29 protein
LEOIKIBE_00041	3.42e-97	-	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LEOIKIBE_00042	5.2e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LEOIKIBE_00043	4.97e-70	-	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
LEOIKIBE_00044	4.05e-152	-	-	-	-	-	-	-	-
LEOIKIBE_00045	1.05e-58	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LEOIKIBE_00046	1.85e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LEOIKIBE_00047	8.72e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LEOIKIBE_00048	1.9e-131	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L4/L1 family
LEOIKIBE_00049	3.86e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LEOIKIBE_00050	3.67e-65	-	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S10p/S20e
LEOIKIBE_00051	0.0	-	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LEOIKIBE_00052	2.91e-104	-	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S7p/S5e
LEOIKIBE_00053	4.16e-85	-	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S12/S23
LEOIKIBE_00054	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	BPG-independent PGAM N-terminus (iPGM_N)
LEOIKIBE_00055	3.37e-97	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase superfamily
LEOIKIBE_00056	1.82e-274	-	-	-	T	-	-	-	PAS domain
LEOIKIBE_00057	0.0	-	-	-	T	-	-	-	Bacterial regulatory protein, Fis family
LEOIKIBE_00058	0.0	-	-	-	O	-	-	-	C-terminal four TMM region of protein-O-mannosyltransferase
LEOIKIBE_00059	3.08e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
LEOIKIBE_00060	0.0	dxs	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LEOIKIBE_00061	1.14e-182	-	-	-	S	-	-	-	Tetratricopeptide repeat
LEOIKIBE_00062	1.1e-125	-	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Recombination protein O N terminal
LEOIKIBE_00063	9.67e-251	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
LEOIKIBE_00064	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
LEOIKIBE_00065	5.03e-230	-	-	-	EP	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
LEOIKIBE_00067	3.07e-155	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
LEOIKIBE_00069	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
LEOIKIBE_00070	4.97e-168	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
LEOIKIBE_00071	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
LEOIKIBE_00072	1.02e-204	-	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
LEOIKIBE_00074	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
LEOIKIBE_00075	3.42e-111	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
LEOIKIBE_00077	1.86e-94	-	-	-	O	-	-	-	OsmC-like protein
LEOIKIBE_00078	0.0	-	-	-	CO	-	-	-	Disulphide bond corrector protein DsbC
LEOIKIBE_00079	4.48e-173	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
LEOIKIBE_00080	5.34e-140	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease
LEOIKIBE_00081	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LEOIKIBE_00082	4.69e-79	rsfS	-	-	S	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LEOIKIBE_00083	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LEOIKIBE_00085	1.29e-257	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
LEOIKIBE_00086	1.25e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Enoyl-CoA hydratase/isomerase
LEOIKIBE_00089	3.07e-301	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	efflux transmembrane transporter activity
LEOIKIBE_00093	9.85e-147	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
LEOIKIBE_00096	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
LEOIKIBE_00097	8.38e-98	-	-	-	-	-	-	-	-
LEOIKIBE_00098	3.14e-192	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
LEOIKIBE_00099	0.0	-	-	-	S	-	-	-	Fungal chitosanase of glycosyl hydrolase group 75
LEOIKIBE_00100	9.68e-221	-	2.5.1.21	-	I	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01006	Squalene/phytoene synthase
LEOIKIBE_00101	0.0	-	-	-	KT	ko:K02584	ko02020,map02020	ko00000,ko00001,ko03000	Bacterial regulatory protein, Fis family
LEOIKIBE_00102	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
LEOIKIBE_00104	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
LEOIKIBE_00107	0.0	-	-	-	-	-	-	-	-
LEOIKIBE_00108	0.0	-	4.1.1.15	-	E	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase conserved domain
LEOIKIBE_00109	6.08e-141	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
LEOIKIBE_00110	0.0	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase alpha chain like domain
LEOIKIBE_00111	4.25e-238	pyrD	1.3.5.2	-	F	ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
LEOIKIBE_00112	4.7e-156	-	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase
LEOIKIBE_00113	1.1e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
LEOIKIBE_00114	1.1e-162	-	-	-	CO	-	-	-	Thioredoxin-like
LEOIKIBE_00115	0.0	-	-	-	C	-	-	-	Cytochrome c554 and c-prime
LEOIKIBE_00116	1.38e-310	-	-	-	S	-	-	-	PFAM CBS domain containing protein
LEOIKIBE_00117	2.13e-311	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	PFAM CBS domain containing protein
LEOIKIBE_00118	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LEOIKIBE_00119	3.01e-49	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal_S15
LEOIKIBE_00120	4.89e-153	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
LEOIKIBE_00121	2.45e-213	-	-	-	D	ko:K19234,ko:K19236	ko01503,map01503	ko00000,ko00001,ko01002,ko01011	ErfK ybiS ycfS ynhG family protein
LEOIKIBE_00122	0.0	-	-	-	S	-	-	-	Terminase
LEOIKIBE_00125	2.53e-199	-	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LEOIKIBE_00126	1.04e-144	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LEOIKIBE_00127	9.86e-168	-	-	-	M	-	-	-	Peptidase family M23
LEOIKIBE_00128	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	PFAM coagulation factor 5 8 type domain protein
LEOIKIBE_00130	1.33e-174	-	-	-	NU	-	-	-	Prepilin-type N-terminal cleavage methylation domain
LEOIKIBE_00132	7.34e-181	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LEOIKIBE_00133	0.0	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
LEOIKIBE_00134	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
LEOIKIBE_00135	6.94e-153	-	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	AAA domain
LEOIKIBE_00137	4.86e-201	-	-	-	S	-	-	-	DisA bacterial checkpoint controller nucleotide-binding
LEOIKIBE_00138	3.62e-143	-	-	-	-	-	-	-	-
LEOIKIBE_00139	1.83e-150	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
LEOIKIBE_00140	8.39e-197	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LEOIKIBE_00141	1.48e-120	-	-	-	M	ko:K06142	-	ko00000	Outer membrane protein (OmpH-like)
LEOIKIBE_00142	5.68e-188	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LEOIKIBE_00143	1.2e-196	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
LEOIKIBE_00144	5.69e-190	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
LEOIKIBE_00145	7.38e-252	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
LEOIKIBE_00147	3.54e-222	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
LEOIKIBE_00148	6.23e-118	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Polynucleotide kinase 3 phosphatase
LEOIKIBE_00149	8.25e-131	-	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
LEOIKIBE_00150	0.0	-	2.7.1.167, 2.7.7.70	-	M	ko:K03272	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	pfkB family carbohydrate kinase
LEOIKIBE_00151	1.06e-44	-	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S21
LEOIKIBE_00152	7.39e-312	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
LEOIKIBE_00153	5.67e-258	-	-	-	S	-	-	-	ankyrin repeats
LEOIKIBE_00154	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
LEOIKIBE_00155	0.0	-	-	-	-	-	-	-	-
LEOIKIBE_00156	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), anti-codon binding domain
LEOIKIBE_00157	9.59e-288	-	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase II
LEOIKIBE_00158	7.32e-105	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LEOIKIBE_00159	8.13e-206	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LEOIKIBE_00160	1.1e-197	-	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SRP54-type protein, GTPase domain
LEOIKIBE_00161	2.62e-262	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Elongator protein 3, MiaB family, Radical SAM
LEOIKIBE_00162	0.0	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
LEOIKIBE_00163	3.22e-182	-	-	-	U	ko:K20276	ko02024,map02024	ko00000,ko00001	domain, Protein
LEOIKIBE_00164	6.87e-153	-	-	-	O	-	-	-	methyltransferase activity
LEOIKIBE_00165	5.92e-289	-	3.5.1.42	-	S	ko:K03742	ko00760,map00760	ko00000,ko00001,ko01000	Competence-damaged protein
LEOIKIBE_00166	0.0	-	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
LEOIKIBE_00167	1.07e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
LEOIKIBE_00171	9.87e-192	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
LEOIKIBE_00172	4.36e-142	-	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S4/S9 N-terminal domain
LEOIKIBE_00173	2.11e-121	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LEOIKIBE_00174	1.11e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LEOIKIBE_00175	3.9e-270	-	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
LEOIKIBE_00176	1.18e-224	-	-	-	M	ko:K07276	-	ko00000	Mitochondrial fission ELM1
LEOIKIBE_00177	9.97e-268	-	-	-	M	-	-	-	Glycosyl transferase 4-like
LEOIKIBE_00178	1.72e-266	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
LEOIKIBE_00179	1.73e-218	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
LEOIKIBE_00180	5.5e-262	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LEOIKIBE_00181	1.41e-267	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Aminomethyltransferase folate-binding domain
LEOIKIBE_00182	6.67e-86	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
LEOIKIBE_00183	0.0	gcvP	1.4.4.2	-	E	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LEOIKIBE_00185	7.22e-149	-	-	-	L	-	-	-	Membrane
LEOIKIBE_00186	0.0	-	-	-	P	ko:K01138	-	ko00000,ko01000	PA14 domain
LEOIKIBE_00187	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DbpA RNA binding domain
LEOIKIBE_00188	1.02e-174	-	-	-	-	-	-	-	-
LEOIKIBE_00189	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
LEOIKIBE_00190	1.65e-241	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
LEOIKIBE_00191	1.84e-105	-	-	-	S	ko:K15977	-	ko00000	DoxX
LEOIKIBE_00192	4.07e-246	-	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR synthase related protein, N-terminal domain
LEOIKIBE_00193	0.0	-	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LEOIKIBE_00194	1.26e-139	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
LEOIKIBE_00196	2.34e-208	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
LEOIKIBE_00197	1.31e-81	-	-	-	DJ	-	-	-	Addiction module toxin, RelE StbE family
LEOIKIBE_00198	8.37e-126	-	4.1.1.36	-	H	ko:K01598	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Flavoprotein
LEOIKIBE_00200	9.81e-261	-	-	-	M	-	-	-	Peptidase family M23
LEOIKIBE_00201	0.0	-	-	-	S	-	-	-	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LEOIKIBE_00202	0.0	-	-	-	L	-	-	-	Polyphosphate kinase 2 (PPK2)
LEOIKIBE_00203	2.48e-173	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
LEOIKIBE_00204	3.35e-105	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
LEOIKIBE_00205	1.61e-277	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
LEOIKIBE_00206	2.4e-160	-	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	DNA / pantothenate metabolism flavoprotein
LEOIKIBE_00207	2.37e-272	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LEOIKIBE_00208	3.57e-235	-	-	-	S	-	-	-	Aspartyl protease
LEOIKIBE_00209	2.89e-310	-	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
LEOIKIBE_00210	9.61e-131	-	-	-	L	-	-	-	Conserved hypothetical protein 95
LEOIKIBE_00211	2.87e-177	-	-	-	-	-	-	-	-
LEOIKIBE_00213	2.58e-225	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
LEOIKIBE_00214	0.0	-	-	-	-	-	-	-	-
LEOIKIBE_00215	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
LEOIKIBE_00217	2.16e-199	-	-	-	S	ko:K06889	-	ko00000	alpha beta
LEOIKIBE_00218	3.34e-106	-	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
LEOIKIBE_00219	1.93e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal prokaryotic L21 protein
LEOIKIBE_00220	2.14e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
LEOIKIBE_00221	6.78e-100	-	-	-	P	ko:K09825	-	ko00000,ko03000	Ferric uptake regulator family
LEOIKIBE_00222	8.34e-178	-	-	-	O	ko:K09013	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
LEOIKIBE_00223	0.0	-	-	-	O	ko:K09014	-	ko00000	Uncharacterized protein family (UPF0051)
LEOIKIBE_00224	2.04e-293	-	-	-	O	ko:K09015	-	ko00000	Uncharacterized protein family (UPF0051)
LEOIKIBE_00225	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
LEOIKIBE_00226	0.0	-	-	-	P	-	-	-	Sulfatase
LEOIKIBE_00227	1.77e-234	-	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Biotin and Thiamin Synthesis associated domain
LEOIKIBE_00228	0.0	-	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
LEOIKIBE_00231	3.2e-76	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
LEOIKIBE_00232	1.08e-73	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
LEOIKIBE_00233	7.63e-220	-	-	-	M	-	-	-	Glycosyl transferase family 2
LEOIKIBE_00234	4.94e-114	flmH	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LEOIKIBE_00235	7.67e-285	-	2.6.1.59	-	M	ko:K02805	-	ko00000,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
LEOIKIBE_00236	4.27e-275	-	-	-	S	-	-	-	COGs COG4299 conserved
LEOIKIBE_00237	7.85e-122	sprT	-	-	K	-	-	-	SprT-like family
LEOIKIBE_00238	3.38e-140	-	-	-	-	-	-	-	-
LEOIKIBE_00239	1.24e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
LEOIKIBE_00240	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LEOIKIBE_00241	4.5e-201	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LEOIKIBE_00242	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LEOIKIBE_00243	1.59e-86	-	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase delta (OSCP) subunit
LEOIKIBE_00244	4.38e-78	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase B/B' CF(0)
LEOIKIBE_00245	1.65e-11	-	-	-	S	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	PFAM H transporting two-sector ATPase C subunit
LEOIKIBE_00246	6.27e-219	-	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	ATP synthase A chain
LEOIKIBE_00247	0.0	-	-	-	-	-	-	-	-
LEOIKIBE_00248	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein dimerisation domain
LEOIKIBE_00249	5.1e-153	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
LEOIKIBE_00250	3.11e-271	-	-	-	S	-	-	-	COGs COG4299 conserved
LEOIKIBE_00251	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
LEOIKIBE_00253	4.09e-218	-	-	-	I	-	-	-	alpha/beta hydrolase fold
LEOIKIBE_00254	1.37e-221	-	-	-	-	-	-	-	-
LEOIKIBE_00255	8.92e-111	-	-	-	U	-	-	-	response to pH
LEOIKIBE_00256	9.39e-183	-	-	-	H	-	-	-	ThiF family
LEOIKIBE_00257	1.18e-224	-	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
LEOIKIBE_00258	4.7e-193	-	-	-	-	-	-	-	-
LEOIKIBE_00259	2.76e-292	-	4.2.1.129, 5.4.99.17	-	I	ko:K06045	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
LEOIKIBE_00260	1.06e-109	-	-	-	S	ko:K15977	-	ko00000	DoxX
LEOIKIBE_00261	1.34e-201	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase, N-terminal
LEOIKIBE_00262	2.46e-307	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LEOIKIBE_00263	1.25e-179	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LEOIKIBE_00264	0.0	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LEOIKIBE_00265	0.0	-	-	-	K	-	-	-	Transcription elongation factor, N-terminal
LEOIKIBE_00266	1.89e-166	-	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	SAICAR synthetase
LEOIKIBE_00267	3.9e-116	-	-	-	-	-	-	-	-
LEOIKIBE_00268	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
LEOIKIBE_00269	3.71e-177	-	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
LEOIKIBE_00271	3.19e-263	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
LEOIKIBE_00273	0.0	lacZ_17	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
LEOIKIBE_00274	1.45e-235	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Actin
LEOIKIBE_00275	0.0	-	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	Ribonuclease E/G family
LEOIKIBE_00276	1.05e-275	-	-	-	K	-	-	-	sequence-specific DNA binding
LEOIKIBE_00277	1.65e-188	-	-	-	-	-	-	-	-
LEOIKIBE_00278	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
LEOIKIBE_00279	5.28e-100	exbD2	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
LEOIKIBE_00280	3.19e-111	aglS	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
LEOIKIBE_00281	9.91e-171	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
LEOIKIBE_00282	2.07e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LEOIKIBE_00283	1.39e-157	-	-	-	S	-	-	-	3D domain
LEOIKIBE_00284	4.63e-227	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
LEOIKIBE_00285	3.37e-177	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
LEOIKIBE_00287	1.97e-81	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
LEOIKIBE_00288	2.51e-151	-	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
LEOIKIBE_00289	1.37e-309	-	-	-	S	-	-	-	PFAM CBS domain containing protein
LEOIKIBE_00290	8.43e-59	-	-	-	S	-	-	-	Zinc ribbon domain
LEOIKIBE_00291	2.79e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEOIKIBE_00293	2.9e-316	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Arginosuccinate synthase
LEOIKIBE_00294	2.35e-114	-	3.1.6.8	-	P	ko:K01134	ko00600,ko04142,map00600,map04142	ko00000,ko00001,ko01000	COG3119 Arylsulfatase A
LEOIKIBE_00295	1.29e-298	-	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	16S rRNA methyltransferase RsmB/F
LEOIKIBE_00296	4.82e-178	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LEOIKIBE_00297	2.6e-164	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
LEOIKIBE_00298	1.07e-142	-	-	-	-	-	-	-	-
LEOIKIBE_00299	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Sulfatase
LEOIKIBE_00303	2.03e-101	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
LEOIKIBE_00304	1.19e-180	-	-	-	S	-	-	-	competence protein
LEOIKIBE_00305	2.92e-70	-	-	-	-	-	-	-	-
LEOIKIBE_00306	4.15e-191	-	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	MazG nucleotide pyrophosphohydrolase domain
LEOIKIBE_00307	3.68e-75	-	-	-	-	-	-	-	-
LEOIKIBE_00308	2.24e-264	-	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
LEOIKIBE_00310	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEOIKIBE_00312	3.69e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LEOIKIBE_00313	9.92e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LEOIKIBE_00314	1.74e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LEOIKIBE_00315	2.58e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LEOIKIBE_00316	6.29e-135	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
LEOIKIBE_00317	3.61e-46	-	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecE/Sec61-gamma subunits of protein translocation complex
LEOIKIBE_00319	9.94e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LEOIKIBE_00321	6.13e-257	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LEOIKIBE_00322	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LEOIKIBE_00323	2.5e-153	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LEOIKIBE_00324	8.38e-282	tig	-	-	O	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LEOIKIBE_00325	0.0	-	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Surface antigen
LEOIKIBE_00326	3.41e-155	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
LEOIKIBE_00327	3.69e-231	-	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
LEOIKIBE_00328	3.38e-169	-	-	-	CO	-	-	-	Protein conserved in bacteria
LEOIKIBE_00330	1.46e-147	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
LEOIKIBE_00331	0.0	-	-	-	P	ko:K07239	-	ko00000	AcrB/AcrD/AcrF family
LEOIKIBE_00332	1.96e-297	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEOIKIBE_00333	5.86e-293	-	-	-	MU	ko:K15725	-	ko00000,ko02000	efflux transmembrane transporter activity
LEOIKIBE_00335	5.25e-205	-	-	-	G	ko:K06867,ko:K07001	-	ko00000	response to abiotic stimulus
LEOIKIBE_00336	0.0	-	-	-	E	-	-	-	PFAM major facilitator superfamily MFS_1
LEOIKIBE_00339	1.66e-215	-	-	-	KQ	-	-	-	Hypothetical methyltransferase
LEOIKIBE_00340	1.54e-290	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LEOIKIBE_00341	0.0	ahcY	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LEOIKIBE_00342	3e-250	rgpB	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
LEOIKIBE_00343	1.87e-248	-	-	-	-	-	-	-	-
LEOIKIBE_00344	3.16e-315	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
LEOIKIBE_00345	1.01e-225	-	-	-	-	-	-	-	-
LEOIKIBE_00346	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
LEOIKIBE_00347	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RecQ zinc-binding
LEOIKIBE_00349	1.51e-301	-	-	-	M	-	-	-	Glycosyl transferases group 1
LEOIKIBE_00350	9.76e-258	-	-	-	S	-	-	-	Glycoside-hydrolase family GH114
LEOIKIBE_00351	0.0	-	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
LEOIKIBE_00352	2.01e-133	-	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	SpoU rRNA Methylase family
LEOIKIBE_00353	3.08e-204	-	3.1.1.53	-	L	ko:K03547,ko:K05970	-	ko00000,ko01000,ko03400	3'-5' exonuclease activity
LEOIKIBE_00354	9.94e-90	-	-	-	K	-	-	-	Helix-turn-helix diphteria tox regulatory element
LEOIKIBE_00355	2.01e-37	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEOIKIBE_00356	8.33e-233	-	-	-	C	-	-	-	Iron-sulfur cluster-binding domain
LEOIKIBE_00357	0.0	-	-	-	L	-	-	-	ATPases associated with a variety of cellular activities
LEOIKIBE_00358	5.65e-191	-	-	-	C	-	-	-	4Fe-4S single cluster domain
LEOIKIBE_00359	2.13e-52	-	-	-	L	-	-	-	CHC2 zinc finger
LEOIKIBE_00360	1.35e-27	-	-	-	L	-	-	-	CHC2 zinc finger
LEOIKIBE_00361	9.59e-77	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4 family domain protein
LEOIKIBE_00362	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
LEOIKIBE_00364	2.83e-303	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
LEOIKIBE_00367	0.0	-	-	-	P	ko:K04759	-	ko00000,ko02000	Ferrous iron transport protein B C terminus
LEOIKIBE_00368	1.92e-46	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
LEOIKIBE_00369	2.48e-40	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
LEOIKIBE_00370	0.0	-	1.11.1.5	-	P	ko:K00428	-	ko00000,ko01000	Di-haem cytochrome c peroxidase
LEOIKIBE_00371	5.44e-229	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LEOIKIBE_00372	1.1e-131	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LEOIKIBE_00373	4.04e-241	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
LEOIKIBE_00374	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
LEOIKIBE_00375	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LEOIKIBE_00376	5.32e-142	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LEOIKIBE_00377	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
LEOIKIBE_00378	2.27e-245	-	-	-	-	-	-	-	-
LEOIKIBE_00379	1.44e-206	-	-	-	-	-	-	-	-
LEOIKIBE_00380	0.0	-	-	-	NU	-	-	-	Type IV pilus assembly protein PilM;
LEOIKIBE_00381	8.03e-169	-	-	-	-	-	-	-	-
LEOIKIBE_00382	3.28e-256	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
LEOIKIBE_00383	1.24e-261	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LEOIKIBE_00384	2.82e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF3313)
LEOIKIBE_00385	3.39e-313	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
LEOIKIBE_00386	2.25e-206	hisG	2.4.2.17	-	E	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
LEOIKIBE_00387	2.09e-10	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
LEOIKIBE_00388	2.87e-289	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
LEOIKIBE_00389	2.81e-167	-	-	-	T	ko:K07657	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
LEOIKIBE_00390	0.0	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Dehydratase family
LEOIKIBE_00392	0.0	-	-	-	T	-	-	-	pathogenesis
LEOIKIBE_00393	1.35e-266	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
LEOIKIBE_00394	2.8e-206	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
LEOIKIBE_00395	1.4e-287	-	4.1.99.19	-	H	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Biotin and Thiamin Synthesis associated domain
LEOIKIBE_00396	0.0	-	-	-	M	-	-	-	Sulfatase
LEOIKIBE_00397	1.86e-291	-	-	-	-	-	-	-	-
LEOIKIBE_00398	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
LEOIKIBE_00399	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2851)
LEOIKIBE_00400	6.39e-119	-	-	-	T	-	-	-	STAS domain
LEOIKIBE_00401	0.0	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
LEOIKIBE_00402	0.0	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
LEOIKIBE_00403	1.04e-246	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
LEOIKIBE_00404	0.0	-	2.1.1.182	-	IJ	ko:K02528	-	ko00000,ko01000,ko03009	Ribosomal RNA adenine dimethylases
LEOIKIBE_00405	2.93e-102	-	-	-	-	-	-	-	-
LEOIKIBE_00406	9.86e-54	-	-	-	-	-	-	-	-
LEOIKIBE_00407	7.41e-120	-	-	-	-	-	-	-	-
LEOIKIBE_00408	2.48e-300	-	-	-	V	ko:K03327	-	ko00000,ko02000	drug transmembrane transporter activity
LEOIKIBE_00409	0.0	-	-	-	P	-	-	-	Cation transport protein
LEOIKIBE_00414	4.04e-30	-	-	-	-	-	-	-	-
LEOIKIBE_00415	4.5e-46	gepA	-	-	K	-	-	-	Phage-associated protein
LEOIKIBE_00421	8.45e-35	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
LEOIKIBE_00422	9.4e-95	-	2.1.1.63	-	H	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LEOIKIBE_00423	1.83e-77	ada	3.2.2.21	-	K	ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	AlkA N-terminal domain
LEOIKIBE_00424	1.56e-08	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LEOIKIBE_00429	1.07e-48	-	-	-	S	-	-	-	Domain of unknown function (DUF932)
LEOIKIBE_00431	4.05e-69	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
LEOIKIBE_00432	7.5e-310	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
LEOIKIBE_00433	1.06e-31	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
LEOIKIBE_00435	2.54e-275	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
LEOIKIBE_00436	2.55e-101	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
LEOIKIBE_00437	4.79e-97	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
LEOIKIBE_00438	6.05e-39	-	-	-	-	-	-	-	-
LEOIKIBE_00441	7.98e-09	-	-	-	S	-	-	-	TM2 domain
LEOIKIBE_00448	3.57e-07	RIPK1	2.7.11.1	-	T	ko:K02861	ko04064,ko04210,ko04217,ko04620,ko04621,ko04622,ko04623,ko04668,ko05160,ko05169,map04064,map04210,map04217,map04620,map04621,map04622,map04623,map04668,map05160,map05169	ko00000,ko00001,ko01000,ko01001	Receptor (TNFRSF)-interacting serine-threonine kinase 1
LEOIKIBE_00450	1.1e-132	-	-	-	S	-	-	-	Virulence protein RhuM family
LEOIKIBE_00451	1.2e-160	-	-	-	S	-	-	-	filamentation induced by cAMP protein Fic
LEOIKIBE_00452	3.72e-113	-	-	-	S	-	-	-	5'-nucleotidase
LEOIKIBE_00453	4e-42	-	-	-	S	-	-	-	von Willebrand factor type A domain
LEOIKIBE_00454	1.37e-05	-	-	-	KLT	-	-	-	Lanthionine synthetase C-like protein
LEOIKIBE_00455	6.76e-30	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
LEOIKIBE_00456	1.48e-31	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
LEOIKIBE_00459	4.6e-149	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
LEOIKIBE_00465	1.24e-263	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
LEOIKIBE_00467	0.0	-	-	-	M	-	-	-	pathogenesis
LEOIKIBE_00472	7.91e-96	-	-	-	C	-	-	-	e3 binding domain
LEOIKIBE_00473	3.93e-128	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
LEOIKIBE_00474	5.31e-266	-	-	-	S	-	-	-	PFAM glycosyl transferase family 2
LEOIKIBE_00475	1.95e-291	-	-	-	-	-	-	-	-
LEOIKIBE_00476	3.3e-261	-	-	-	S	-	-	-	Glycosyltransferase like family 2
LEOIKIBE_00477	3.06e-226	-	-	-	S	-	-	-	Glycosyl transferase family 11
LEOIKIBE_00478	3.93e-272	-	-	GT2	S	ko:K19427	-	ko00000,ko01000	PFAM glycosyl transferase family 2
LEOIKIBE_00480	1.44e-281	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
LEOIKIBE_00481	0.0	-	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Polyphosphate kinase middle domain
LEOIKIBE_00482	0.0	-	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
LEOIKIBE_00483	9.49e-263	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
LEOIKIBE_00484	1.29e-192	map	3.4.11.18	-	J	ko:K01265	-	ko00000,ko01000,ko01002	Metallopeptidase family M24
LEOIKIBE_00485	1.51e-153	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LEOIKIBE_00486	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LEOIKIBE_00488	6.42e-101	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
LEOIKIBE_00489	3.38e-102	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LEOIKIBE_00490	1.67e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LEOIKIBE_00491	2.25e-105	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LEOIKIBE_00492	4.08e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LEOIKIBE_00493	4.41e-137	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LEOIKIBE_00494	1.53e-47	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S L24/mitochondrial 39S L24
LEOIKIBE_00495	4.9e-207	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LEOIKIBE_00496	9.87e-122	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
LEOIKIBE_00497	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
LEOIKIBE_00498	0.0	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 Helicase protein
LEOIKIBE_00499	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
LEOIKIBE_00501	4.39e-286	-	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
LEOIKIBE_00502	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Collagenase
LEOIKIBE_00504	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LEOIKIBE_00505	6.52e-75	-	-	-	L	-	-	-	Cupin 2, conserved barrel domain protein
LEOIKIBE_00506	1.18e-128	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
LEOIKIBE_00508	3.03e-296	-	-	-	EGP	-	-	-	Major facilitator Superfamily
LEOIKIBE_00509	4.75e-215	-	-	-	K	-	-	-	LysR substrate binding domain
LEOIKIBE_00510	2.76e-270	-	-	-	S	-	-	-	tRNA-splicing ligase RtcB
LEOIKIBE_00511	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
LEOIKIBE_00513	2.51e-284	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEOIKIBE_00515	1.05e-132	-	-	-	D	-	-	-	ErfK ybiS ycfS ynhG family protein
LEOIKIBE_00516	0.0	-	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
LEOIKIBE_00517	8.8e-169	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
LEOIKIBE_00521	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Bacterial DNA topoisomeraes I ATP-binding domain
LEOIKIBE_00522	4.53e-100	-	-	-	-	-	-	-	-
LEOIKIBE_00523	0.0	-	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase HemD
LEOIKIBE_00524	6.42e-101	-	-	-	S	-	-	-	peptidase
LEOIKIBE_00525	1.49e-171	-	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
LEOIKIBE_00526	2.1e-99	-	-	-	S	-	-	-	peptidase
LEOIKIBE_00527	0.0	-	-	-	S	-	-	-	pathogenesis
LEOIKIBE_00528	0.0	-	-	-	V	ko:K18095	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	AcrB/AcrD/AcrF family
LEOIKIBE_00529	2.88e-242	-	-	-	M	ko:K18094	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	Biotin-lipoyl like
LEOIKIBE_00530	6.38e-191	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
LEOIKIBE_00531	6.82e-223	-	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
LEOIKIBE_00532	9.47e-236	-	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
LEOIKIBE_00533	1.63e-298	-	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
LEOIKIBE_00534	8.16e-207	-	-	-	S	ko:K09949	-	ko00000	Protein of unknown function (DUF1009)
LEOIKIBE_00537	4.67e-91	-	-	-	-	-	-	-	-
LEOIKIBE_00538	4.33e-171	yyaQ	-	-	V	-	-	-	Protein conserved in bacteria
LEOIKIBE_00539	5.06e-192	-	-	-	M	-	-	-	Glycosyl transferase WecB/TagA/CpsF family
LEOIKIBE_00540	5.05e-188	-	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Metallo-beta-lactamase superfamily
LEOIKIBE_00541	0.0	-	-	-	L	ko:K03631	-	ko00000,ko03400	RecF/RecN/SMC N terminal domain
LEOIKIBE_00542	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
LEOIKIBE_00543	2.85e-245	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
LEOIKIBE_00544	9.29e-132	-	-	-	J	ko:K02356	-	ko00000,ko03012	Elongation factor P (EF-P) OB domain
LEOIKIBE_00545	1.2e-105	-	-	-	S	-	-	-	ACT domain protein
LEOIKIBE_00546	1.95e-312	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
LEOIKIBE_00547	3.06e-85	-	-	-	M	ko:K03282	-	ko00000,ko02000	Large-conductance mechanosensitive channel, MscL
LEOIKIBE_00548	9.73e-276	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
LEOIKIBE_00549	2.85e-285	-	-	-	EGP	-	-	-	Major facilitator Superfamily
LEOIKIBE_00550	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
LEOIKIBE_00551	1.04e-266	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
LEOIKIBE_00553	1.96e-121	ngr	-	-	C	-	-	-	Rubrerythrin
LEOIKIBE_00555	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1705)
LEOIKIBE_00556	0.0	-	-	-	M	-	-	-	Glycosyl Hydrolase Family 88
LEOIKIBE_00557	0.0	-	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
LEOIKIBE_00558	3.8e-43	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	CTP reductase activity
LEOIKIBE_00559	4.34e-188	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
LEOIKIBE_00560	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
LEOIKIBE_00561	0.0	-	-	-	T	-	-	-	Histidine kinase
LEOIKIBE_00562	1.33e-110	-	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
LEOIKIBE_00563	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
LEOIKIBE_00564	3.64e-25	-	-	-	M	ko:K13730	ko05100,map05100	ko00000,ko00001	leucine-rich repeat-containing protein typical subtype
LEOIKIBE_00569	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
LEOIKIBE_00570	7.36e-55	himA	-	-	L	ko:K03530,ko:K04764,ko:K05788	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
LEOIKIBE_00571	0.0	-	-	-	-	-	-	-	-
LEOIKIBE_00574	1.15e-303	-	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	tRNA (Uracil-5-)-methyltransferase
LEOIKIBE_00575	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LEOIKIBE_00576	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
LEOIKIBE_00577	8.07e-259	-	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
LEOIKIBE_00578	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
LEOIKIBE_00579	1.71e-203	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LEOIKIBE_00580	1.73e-307	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LEOIKIBE_00581	0.0	-	-	-	-	-	-	-	-
LEOIKIBE_00582	8.36e-162	-	-	-	S	-	-	-	SWIM zinc finger
LEOIKIBE_00583	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase C-terminal
LEOIKIBE_00584	0.0	-	-	-	U	ko:K03321	-	ko00000,ko02000	Sulfate permease family
LEOIKIBE_00585	8.76e-126	-	-	-	-	-	-	-	-
LEOIKIBE_00586	1.04e-109	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LEOIKIBE_00587	0.0	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
LEOIKIBE_00590	5.88e-277	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
LEOIKIBE_00591	1.58e-239	-	-	-	O	-	-	-	Trypsin-like peptidase domain
LEOIKIBE_00592	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Transglycosylase
LEOIKIBE_00593	2.41e-282	-	-	-	S	ko:K09760	-	ko00000	RmuC family
LEOIKIBE_00595	8.63e-167	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
LEOIKIBE_00596	1.25e-132	-	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LEOIKIBE_00597	5.32e-208	-	-	-	S	-	-	-	RDD family
LEOIKIBE_00598	0.0	-	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MacB-like periplasmic core domain
LEOIKIBE_00599	3.39e-210	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
LEOIKIBE_00600	2.27e-90	-	-	-	S	ko:K09793	-	ko00000	Protein of unknown function (DUF456)
LEOIKIBE_00601	4.81e-58	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
LEOIKIBE_00602	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
LEOIKIBE_00603	5.08e-263	-	-	-	S	-	-	-	Peptidase family M28
LEOIKIBE_00604	1.12e-245	-	-	-	I	-	-	-	alpha/beta hydrolase fold
LEOIKIBE_00605	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LEOIKIBE_00606	1.45e-185	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase (SPase) II
LEOIKIBE_00607	1.97e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
LEOIKIBE_00608	3.13e-114	-	-	-	P	-	-	-	Rhodanese-like domain
LEOIKIBE_00609	2.59e-296	-	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LEOIKIBE_00610	0.0	-	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LEOIKIBE_00611	0.000231	-	2.7.11.1, 2.7.11.17	-	T	ko:K08794,ko:K13412,ko:K17530	ko04626,ko04921,ko04925,ko05145,map04626,map04921,map04925,map05145	ko00000,ko00001,ko01000,ko01001	protein serine/threonine kinase activity
LEOIKIBE_00613	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LEOIKIBE_00614	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
LEOIKIBE_00615	4.12e-100	-	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Glyoxalase-like domain
LEOIKIBE_00616	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
LEOIKIBE_00618	3.41e-55	-	-	-	I	-	-	-	PFAM biotin lipoyl attachment domain-containing protein
LEOIKIBE_00619	0.0	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
LEOIKIBE_00620	3.17e-190	-	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
LEOIKIBE_00621	0.0	-	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
LEOIKIBE_00623	9.53e-206	-	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LEOIKIBE_00624	8.83e-270	-	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
LEOIKIBE_00625	1.13e-228	-	2.7.1.11	-	G	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Phosphofructokinase
LEOIKIBE_00626	4.51e-182	-	-	-	L	ko:K10800	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	uracil-dna glycosylase
LEOIKIBE_00628	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEOIKIBE_00629	0.0	poxB	1.2.3.3, 1.2.5.1	-	EH	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
LEOIKIBE_00630	0.000225	-	-	-	-	-	-	-	-
LEOIKIBE_00631	0.0	-	-	-	G	-	-	-	alpha-galactosidase
LEOIKIBE_00633	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
LEOIKIBE_00634	3.75e-285	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEOIKIBE_00635	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LEOIKIBE_00636	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
LEOIKIBE_00638	6.08e-178	-	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
LEOIKIBE_00640	7.23e-164	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
LEOIKIBE_00643	0.0	-	-	-	L	-	-	-	DNA restriction-modification system
LEOIKIBE_00647	3.92e-115	-	-	-	-	-	-	-	-
LEOIKIBE_00648	2.17e-178	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
LEOIKIBE_00650	2.31e-162	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LEOIKIBE_00651	2.04e-258	tdh	1.1.1.103	-	E	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
LEOIKIBE_00652	0.0	-	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Carbohydrate phosphorylase
LEOIKIBE_00653	3.54e-181	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
LEOIKIBE_00654	6.09e-81	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	ArsC family
LEOIKIBE_00655	0.0	-	-	-	J	ko:K07576	-	ko00000	Beta-Casp domain
LEOIKIBE_00656	8.48e-56	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LEOIKIBE_00657	3.94e-243	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
LEOIKIBE_00658	3.99e-240	-	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
LEOIKIBE_00659	2.05e-28	-	-	-	-	-	-	-	-
LEOIKIBE_00660	8.07e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	tRNA (Guanine-1)-methyltransferase
LEOIKIBE_00661	8.8e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LEOIKIBE_00662	1.66e-87	-	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
LEOIKIBE_00663	0.0	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
LEOIKIBE_00664	1.26e-136	-	-	-	C	-	-	-	Nitroreductase family
LEOIKIBE_00665	5.02e-110	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
LEOIKIBE_00669	1.3e-41	-	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
LEOIKIBE_00673	0.000185	-	-	-	M	ko:K07126,ko:K13582	ko04112,map04112	ko00000,ko00001	COG0790 FOG TPR repeat, SEL1 subfamily
LEOIKIBE_00674	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
LEOIKIBE_00678	3.69e-78	-	-	-	F	-	-	-	Terminase
LEOIKIBE_00682	7.29e-211	-	-	-	M	-	-	-	Peptidase family M23
LEOIKIBE_00683	2.05e-228	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
LEOIKIBE_00684	8.33e-183	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LEOIKIBE_00685	4.21e-121	-	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
LEOIKIBE_00686	4.14e-175	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate reductase, N-terminus
LEOIKIBE_00687	1.02e-203	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
LEOIKIBE_00696	3.01e-188	-	5.2.1.8	-	O	ko:K03773	-	ko00000,ko01000,ko03110	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
LEOIKIBE_00697	4.4e-138	-	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LEOIKIBE_00698	5.8e-271	-	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
LEOIKIBE_00699	2.09e-207	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
LEOIKIBE_00700	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
LEOIKIBE_00701	4.69e-165	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
LEOIKIBE_00708	1.97e-135	panZ	-	-	K	-	-	-	-acetyltransferase
LEOIKIBE_00709	5.17e-220	-	-	-	E	ko:K00612	-	ko00000,ko01000	lipolytic protein G-D-S-L family
LEOIKIBE_00710	7.15e-221	-	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
LEOIKIBE_00711	0.0	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
LEOIKIBE_00712	5.5e-176	-	-	-	-	-	-	-	-
LEOIKIBE_00714	9.55e-242	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LEOIKIBE_00715	1.3e-208	-	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Polyprenyl synthetase
LEOIKIBE_00716	4.86e-199	-	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
LEOIKIBE_00717	3.45e-157	-	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
LEOIKIBE_00718	1.6e-216	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
LEOIKIBE_00719	7.46e-314	-	-	-	G	-	-	-	Trehalase
LEOIKIBE_00720	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
LEOIKIBE_00721	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
LEOIKIBE_00722	1.1e-34	-	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
LEOIKIBE_00723	4.9e-76	-	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	Ribonuclease P
LEOIKIBE_00724	4.61e-61	-	-	-	S	ko:K08998	-	ko00000	Haemolytic
LEOIKIBE_00725	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
LEOIKIBE_00726	0.0	-	1.4.1.13, 1.4.1.14	-	E	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
LEOIKIBE_00727	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
LEOIKIBE_00728	0.0	-	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
LEOIKIBE_00729	2.19e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase small chain, CPSase domain
LEOIKIBE_00730	6.96e-265	-	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LEOIKIBE_00731	1.53e-267	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
LEOIKIBE_00732	1.45e-296	-	-	-	C	-	-	-	Na+/H+ antiporter family
LEOIKIBE_00733	1.11e-236	-	-	-	-	-	-	-	-
LEOIKIBE_00734	2.4e-229	-	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphomannose isomerase type I
LEOIKIBE_00735	1.24e-179	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
LEOIKIBE_00736	1.93e-117	ispF	4.6.1.12	-	I	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LEOIKIBE_00737	4.01e-186	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
LEOIKIBE_00738	0.0	-	-	-	M	-	-	-	PFAM glycosyl transferase family 51
LEOIKIBE_00739	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
LEOIKIBE_00740	6.23e-97	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
LEOIKIBE_00741	6.34e-183	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
LEOIKIBE_00742	0.0	-	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LEOIKIBE_00743	1.27e-99	-	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Predicted SPOUT methyltransferase
LEOIKIBE_00744	1.67e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S9/S16
LEOIKIBE_00745	2.79e-97	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LEOIKIBE_00746	1.07e-30	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LEOIKIBE_00747	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LEOIKIBE_00748	1.69e-174	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
LEOIKIBE_00750	4.03e-174	-	-	-	D	-	-	-	Phage-related minor tail protein
LEOIKIBE_00752	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEOIKIBE_00753	3.36e-62	-	-	-	L	ko:K09747	-	ko00000	YbaB/EbfC DNA-binding family
LEOIKIBE_00754	2.68e-253	-	-	-	N	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease Exonuclease Phosphatase
LEOIKIBE_00755	0.0	-	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	DHHA2
LEOIKIBE_00757	1.5e-186	-	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
LEOIKIBE_00758	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
LEOIKIBE_00760	0.0	-	-	-	G	-	-	-	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain
LEOIKIBE_00763	1.38e-23	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
LEOIKIBE_00764	3.17e-20	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
LEOIKIBE_00767	2.54e-131	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
LEOIKIBE_00771	4.13e-28	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
LEOIKIBE_00772	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LEOIKIBE_00773	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LEOIKIBE_00774	2.54e-132	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LEOIKIBE_00775	3.88e-263	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
LEOIKIBE_00776	1.76e-233	-	2.7.11.1	-	T	ko:K08884,ko:K12132,ko:K20333	ko02024,map02024	ko00000,ko00001,ko01000,ko01001	PFAM Formylglycine-generating sulfatase enzyme
LEOIKIBE_00778	2.06e-196	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
LEOIKIBE_00779	1.93e-138	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
LEOIKIBE_00780	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
LEOIKIBE_00781	7.73e-278	-	-	-	C	-	-	-	Aldo/keto reductase family
LEOIKIBE_00782	6.71e-90	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
LEOIKIBE_00783	6.99e-260	-	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
LEOIKIBE_00784	8.44e-292	-	-	-	-	-	-	-	-
LEOIKIBE_00785	0.0	-	-	-	S	-	-	-	von Willebrand factor type A domain
LEOIKIBE_00786	0.0	-	-	-	S	-	-	-	Aerotolerance regulator N-terminal
LEOIKIBE_00787	5.75e-208	-	-	-	S	-	-	-	Protein of unknown function DUF58
LEOIKIBE_00788	0.0	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
LEOIKIBE_00789	1.78e-241	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
LEOIKIBE_00790	0.0	-	-	-	-	-	-	-	-
LEOIKIBE_00791	1.49e-237	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
LEOIKIBE_00792	1.04e-296	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
LEOIKIBE_00794	1.63e-239	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LEOIKIBE_00796	5.75e-202	-	-	-	O	-	-	-	stress-induced mitochondrial fusion
LEOIKIBE_00797	1.04e-203	-	-	-	S	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
LEOIKIBE_00798	1.03e-121	-	-	-	M	ko:K03098	-	ko00000,ko04147	Lipocalin-like domain
LEOIKIBE_00799	1.35e-236	-	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LEOIKIBE_00800	2.8e-187	-	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
LEOIKIBE_00801	9.64e-153	-	-	-	K	-	-	-	Transcriptional regulator
LEOIKIBE_00803	0.0	-	-	-	P	-	-	-	Sulfatase
LEOIKIBE_00804	1.04e-78	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
LEOIKIBE_00805	4.6e-305	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LEOIKIBE_00806	3.59e-47	-	-	-	E	-	-	-	Aminotransferase class I and II
LEOIKIBE_00807	0.0	-	-	-	E	-	-	-	Aminotransferase class I and II
LEOIKIBE_00808	1.76e-219	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LEOIKIBE_00809	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha galactosidase A
LEOIKIBE_00810	1.04e-49	-	-	-	-	-	-	-	-
LEOIKIBE_00811	1.45e-55	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
LEOIKIBE_00812	1.1e-234	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
LEOIKIBE_00813	2.13e-96	-	-	-	L	ko:K07447	-	ko00000,ko01000	Likely ribonuclease with RNase H fold.
LEOIKIBE_00814	1.98e-258	-	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
LEOIKIBE_00815	1.06e-173	-	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LEOIKIBE_00816	0.0	-	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	TopoisomeraseII
LEOIKIBE_00817	1.42e-209	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
LEOIKIBE_00819	0.0	-	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	HELICc2
LEOIKIBE_00820	4.82e-179	cbiO	-	-	P	ko:K02006,ko:K02008,ko:K16784,ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase activity
LEOIKIBE_00821	2.42e-195	cbiQ	-	-	P	ko:K02007,ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transmembrane transporter activity
LEOIKIBE_00822	8.77e-239	cbiM	-	-	P	ko:K02007,ko:K02009,ko:K16915	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt ion transport
LEOIKIBE_00824	5.69e-18	-	-	-	S	-	-	-	Lipocalin-like
LEOIKIBE_00825	3.2e-209	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
LEOIKIBE_00826	7.38e-227	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
LEOIKIBE_00827	1.06e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L9, N-terminal domain
LEOIKIBE_00828	0.0	-	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT/IMPCHase bienzyme
LEOIKIBE_00829	5.64e-173	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LEOIKIBE_00830	9.05e-85	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	4'-phosphopantetheinyl transferase superfamily
LEOIKIBE_00832	0.0	pckG	4.1.1.32	-	C	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
LEOIKIBE_00833	4.02e-166	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
LEOIKIBE_00834	0.0	-	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	RecG wedge domain
LEOIKIBE_00836	0.0	-	-	-	C	ko:K00184	-	ko00000	4Fe-4S dicluster domain
LEOIKIBE_00837	6.18e-180	-	-	-	C	-	-	-	Cytochrome c7 and related cytochrome c
LEOIKIBE_00838	7e-301	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
LEOIKIBE_00840	7.72e-256	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Iron-containing alcohol dehydrogenase
LEOIKIBE_00850	0.0	-	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
LEOIKIBE_00851	1.17e-130	-	-	-	D	ko:K06287	-	ko00000	Maf-like protein
LEOIKIBE_00852	2.66e-290	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LEOIKIBE_00854	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
LEOIKIBE_00855	0.0	-	-	-	GK	-	-	-	carbohydrate kinase activity
LEOIKIBE_00856	4.34e-202	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
LEOIKIBE_00857	6.68e-207	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LEOIKIBE_00858	0.0	-	-	-	I	-	-	-	Acetyltransferase (GNAT) domain
LEOIKIBE_00859	2.8e-143	-	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Cytidylate kinase
LEOIKIBE_00860	8.17e-147	-	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
LEOIKIBE_00861	6.38e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LEOIKIBE_00862	3.75e-121	actI	1.5.1.36	-	S	ko:K00484	ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220	ko00000,ko00001,ko01000	FMN binding
LEOIKIBE_00863	3.86e-162	rnc	3.1.26.3	-	K	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LEOIKIBE_00864	0.0	-	-	-	P	ko:K07221	-	ko00000,ko02000	Phosphate-selective porin O and P
LEOIKIBE_00865	1.35e-18	-	-	-	-	-	-	-	-
LEOIKIBE_00866	1.08e-180	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
LEOIKIBE_00867	2.91e-164	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Tetrapyrrole (Corrin/Porphyrin) Methylases
LEOIKIBE_00868	7.51e-116	-	-	-	S	-	-	-	Lipopolysaccharide-assembly
LEOIKIBE_00869	1.67e-170	-	-	-	S	ko:K05807	-	ko00000,ko02000	Outer membrane lipoprotein
LEOIKIBE_00870	4.98e-117	hisI	3.5.4.19	-	E	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-AMP cyclohydrolase
LEOIKIBE_00871	1.27e-223	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
LEOIKIBE_00872	1.41e-120	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	G/U mismatch-specific uracil-DNA glycosylase activity
LEOIKIBE_00873	1.77e-196	-	-	-	-	-	-	-	-
LEOIKIBE_00874	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
LEOIKIBE_00875	1.56e-137	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
LEOIKIBE_00877	5.06e-182	-	-	-	Q	-	-	-	methyltransferase activity
LEOIKIBE_00878	0.0	-	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	NAD synthase
LEOIKIBE_00879	2.28e-79	-	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
LEOIKIBE_00881	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	exo-alpha-(2->6)-sialidase activity
LEOIKIBE_00882	7.72e-279	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
LEOIKIBE_00883	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR/Asp-box repeat
LEOIKIBE_00884	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
LEOIKIBE_00891	1.17e-08	-	-	-	S	ko:K06867	-	ko00000	Ankyrin repeat protein
LEOIKIBE_00896	2.22e-53	draG	3.2.2.24	-	O	ko:K05521	-	ko00000,ko01000	ADP-ribosylglycohydrolase
LEOIKIBE_00899	1.88e-162	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
LEOIKIBE_00903	1.4e-28	-	-	-	C	ko:K06871	-	ko00000	PFAM Radical SAM domain protein
LEOIKIBE_00905	5.47e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LEOIKIBE_00906	3.87e-238	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEOIKIBE_00907	7.16e-280	-	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	FAD binding domain
LEOIKIBE_00908	2.95e-213	MA20_42350	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyl transferase, family 2
LEOIKIBE_00909	2.19e-247	-	-	-	M	-	-	-	Glycosyl transferase, family 2
LEOIKIBE_00910	1.78e-240	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
LEOIKIBE_00911	0.0	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
LEOIKIBE_00912	1.7e-301	-	4.2.1.129, 5.4.99.17, 5.5.1.16	-	I	ko:K06045,ko:K17811	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
LEOIKIBE_00913	4.58e-256	-	-	-	M	ko:K02022	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEOIKIBE_00914	5.24e-159	-	-	-	S	-	-	-	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LEOIKIBE_00916	5.12e-71	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
LEOIKIBE_00917	5.48e-296	-	-	-	-	-	-	-	-
LEOIKIBE_00918	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
LEOIKIBE_00920	0.0	-	-	-	T	-	-	-	pathogenesis
LEOIKIBE_00921	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LEOIKIBE_00922	7.57e-114	ywrF	-	-	S	-	-	-	FMN binding
LEOIKIBE_00923	4.59e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
LEOIKIBE_00924	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
LEOIKIBE_00925	7.64e-307	-	-	-	M	-	-	-	OmpA family
LEOIKIBE_00926	0.0	-	6.3.2.45	-	M	ko:K02558	-	ko00000,ko01000	Mur ligase family, catalytic domain
LEOIKIBE_00927	5.39e-220	-	-	-	E	-	-	-	Phosphoserine phosphatase
LEOIKIBE_00928	1.74e-168	-	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
LEOIKIBE_00931	6.68e-198	-	2.5.1.55	-	M	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	DAHP synthetase I family
LEOIKIBE_00932	6.36e-171	cbiX	4.99.1.3	-	S	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	sirohydrochlorin cobaltochelatase activity
LEOIKIBE_00933	5.88e-163	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S2
LEOIKIBE_00934	2.05e-198	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LEOIKIBE_00935	3.61e-172	-	-	-	E	-	-	-	ATPases associated with a variety of cellular activities
LEOIKIBE_00937	5.91e-280	-	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate synthase
LEOIKIBE_00938	0.0	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
LEOIKIBE_00939	0.0	-	-	-	O	-	-	-	Trypsin
LEOIKIBE_00940	4.99e-274	-	-	-	-	-	-	-	-
LEOIKIBE_00941	6.22e-146	-	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
LEOIKIBE_00942	0.0	-	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase family (aconitate hydratase)
LEOIKIBE_00943	7.14e-141	-	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
LEOIKIBE_00944	6.69e-239	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
LEOIKIBE_00945	1.15e-238	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LEOIKIBE_00946	1.04e-215	-	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	POTRA domain, FtsQ-type
LEOIKIBE_00947	1.68e-227	ddl	6.3.2.4	-	M	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	D-ala D-ala ligase N-terminus
LEOIKIBE_00948	0.0	murB	-	-	M	-	-	-	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
LEOIKIBE_00949	1.12e-266	-	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LEOIKIBE_00950	7.71e-277	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Cell cycle protein
LEOIKIBE_00951	3.05e-155	mltD	-	CBM50	M	ko:K08307,ko:K12204,ko:K19224	-	ko00000,ko01000,ko01002,ko01011,ko02044	LysM domain
LEOIKIBE_00952	1.45e-314	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LEOIKIBE_00953	8.1e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LEOIKIBE_00954	0.0	-	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Mur ligase middle domain
LEOIKIBE_00955	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LEOIKIBE_00956	0.0	-	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein dimerisation domain
LEOIKIBE_00958	0.0	rsmH	2.1.1.199	-	M	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LEOIKIBE_00959	4.54e-105	-	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
LEOIKIBE_00960	5.27e-189	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
LEOIKIBE_00961	1.85e-146	-	-	-	S	-	-	-	UPF0126 domain
LEOIKIBE_00962	1.25e-92	-	-	-	V	-	-	-	endonuclease activity
LEOIKIBE_00963	8.33e-316	mnmE	-	-	J	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LEOIKIBE_00964	4.71e-264	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LEOIKIBE_00965	1.79e-204	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LEOIKIBE_00966	4.17e-184	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
LEOIKIBE_00967	4.96e-271	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
LEOIKIBE_00968	2.16e-143	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
LEOIKIBE_00969	1.34e-282	-	-	-	M	-	-	-	Glycosyl transferases group 1
LEOIKIBE_00970	9.11e-289	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
LEOIKIBE_00971	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
LEOIKIBE_00974	1.43e-120	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
LEOIKIBE_00975	0.0	-	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase / GMP reductase domain
LEOIKIBE_00976	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	GMP synthase C terminal domain
LEOIKIBE_00977	1.58e-138	-	-	-	S	-	-	-	Maltose acetyltransferase
LEOIKIBE_00978	2.15e-151	ppaX_1	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
LEOIKIBE_00979	2.21e-177	-	-	-	S	-	-	-	NYN domain
LEOIKIBE_00980	5.05e-233	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
LEOIKIBE_00981	1.06e-127	-	-	-	-	-	-	-	-
LEOIKIBE_00982	1.97e-255	-	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LEOIKIBE_00983	1.15e-151	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
LEOIKIBE_00984	2.72e-76	-	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
LEOIKIBE_00985	9e-65	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LEOIKIBE_00986	3e-221	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
LEOIKIBE_00987	2.68e-170	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LEOIKIBE_00988	2.08e-241	-	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
LEOIKIBE_00990	4.21e-207	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
LEOIKIBE_00991	4.53e-244	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
LEOIKIBE_00992	8.27e-250	-	-	-	S	-	-	-	Glycosyltransferase like family 2
LEOIKIBE_00993	1.57e-234	-	-	GT9	M	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	ADP-heptose-lipopolysaccharide heptosyltransferase activity
LEOIKIBE_00994	1.31e-244	-	5.1.3.20	-	M	ko:K03274	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-beta hydroxysteroid dehydrogenase/isomerase family
LEOIKIBE_00995	6.72e-289	-	-	-	M	-	-	-	Glycosyltransferase like family 2
LEOIKIBE_00996	2e-202	-	-	-	-	-	-	-	-
LEOIKIBE_00997	1.68e-308	-	-	-	M	-	-	-	Glycosyl transferases group 1
LEOIKIBE_00998	1.43e-250	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
LEOIKIBE_00999	0.0	-	-	-	I	-	-	-	Acyltransferase family
LEOIKIBE_01000	1.43e-255	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
LEOIKIBE_01003	0.0	-	-	-	P	-	-	-	Citrate transporter
LEOIKIBE_01005	6.56e-112	-	-	-	S	ko:K08999	-	ko00000	Bifunctional nuclease
LEOIKIBE_01006	5.58e-110	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
LEOIKIBE_01007	0.0	-	-	-	E	-	-	-	Transglutaminase-like
LEOIKIBE_01008	5.07e-157	-	-	-	C	-	-	-	Nitroreductase family
LEOIKIBE_01010	0.0	-	3.2.1.23	-	G	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
LEOIKIBE_01011	4.57e-181	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
LEOIKIBE_01012	1.69e-242	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
LEOIKIBE_01013	1.72e-290	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
LEOIKIBE_01014	8.86e-317	hsrA	-	-	EGP	-	-	-	Major facilitator Superfamily
LEOIKIBE_01015	7.17e-104	yciA	-	-	I	ko:K10806	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	acyl-coa hydrolase
LEOIKIBE_01018	3.1e-207	-	-	-	IQ	-	-	-	KR domain
LEOIKIBE_01019	3.96e-247	-	-	-	M	-	-	-	Alginate lyase
LEOIKIBE_01020	1.3e-115	-	-	-	L	-	-	-	Staphylococcal nuclease homologues
LEOIKIBE_01023	3.45e-121	-	-	-	K	-	-	-	ParB domain protein nuclease
LEOIKIBE_01024	0.0	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase
LEOIKIBE_01026	1.55e-05	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
LEOIKIBE_01027	1.4e-20	-	-	-	N	-	-	-	mRNA binding
LEOIKIBE_01043	7.66e-130	-	-	-	S	-	-	-	Glycosyl hydrolase 108
LEOIKIBE_01047	7.6e-246	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
LEOIKIBE_01049	1.45e-258	-	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LEOIKIBE_01051	4.01e-157	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
LEOIKIBE_01052	2.07e-262	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	RibD C-terminal domain
LEOIKIBE_01053	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LEOIKIBE_01054	4.27e-273	-	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
LEOIKIBE_01055	0.0	-	-	-	O	-	-	-	Trypsin
LEOIKIBE_01056	7.97e-108	-	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
LEOIKIBE_01057	0.0	-	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Oligonucleotide/oligosaccharide-binding (OB)-fold
LEOIKIBE_01058	3.52e-161	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
LEOIKIBE_01059	0.0	-	-	-	P	-	-	-	Cation transport protein
LEOIKIBE_01061	2.58e-178	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LEOIKIBE_01062	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
LEOIKIBE_01063	3.2e-70	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
LEOIKIBE_01064	1.32e-101	manC	-	-	S	-	-	-	Cupin domain
LEOIKIBE_01065	0.0	-	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LEOIKIBE_01067	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
LEOIKIBE_01068	2.92e-187	pppL	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	protein serine/threonine phosphatase activity
LEOIKIBE_01069	4.34e-152	-	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Glycerol-3-phosphate acyltransferase
LEOIKIBE_01070	9.43e-235	gpsA	1.1.1.94	-	C	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
LEOIKIBE_01071	1.01e-100	-	-	-	-	-	-	-	-
LEOIKIBE_01073	1.99e-263	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
LEOIKIBE_01074	5.38e-313	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
LEOIKIBE_01075	0.0	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
LEOIKIBE_01076	4.94e-05	-	-	-	-	-	-	-	-
LEOIKIBE_01077	4.56e-69	-	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
LEOIKIBE_01078	8.68e-267	-	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
LEOIKIBE_01079	6.76e-209	-	-	-	S	-	-	-	Rhomboid family
LEOIKIBE_01080	1.52e-268	-	-	-	E	-	-	-	FAD dependent oxidoreductase
LEOIKIBE_01081	2.64e-267	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LEOIKIBE_01085	3.17e-06	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
LEOIKIBE_01086	2.02e-40	-	-	-	-	-	-	-	-
LEOIKIBE_01087	2.37e-57	-	-	-	S	-	-	-	Protein of unknown function, DUF488
LEOIKIBE_01088	1.14e-78	-	-	-	KT	-	-	-	Peptidase S24-like
LEOIKIBE_01094	2.59e-50	-	-	-	S	-	-	-	AAA domain
LEOIKIBE_01103	8.69e-140	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
LEOIKIBE_01105	9.76e-34	-	-	-	KL	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
LEOIKIBE_01106	2.76e-162	-	-	-	-	-	-	-	-
LEOIKIBE_01107	2.04e-40	MA20_41110	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Formyl transferase
LEOIKIBE_01112	2.17e-19	-	-	-	-	-	-	-	-
LEOIKIBE_01113	2.05e-06	-	-	-	L	-	-	-	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LEOIKIBE_01118	1.66e-87	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
LEOIKIBE_01123	9.92e-65	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
LEOIKIBE_01125	1.32e-57	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
LEOIKIBE_01129	1.28e-74	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
LEOIKIBE_01131	5.09e-267	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
LEOIKIBE_01132	1.89e-255	-	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
LEOIKIBE_01133	2.84e-286	-	-	-	S	-	-	-	Phosphotransferase enzyme family
LEOIKIBE_01134	1.9e-258	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LEOIKIBE_01136	2.74e-138	-	-	-	T	-	-	-	histone H2A K63-linked ubiquitination
LEOIKIBE_01137	1.62e-49	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LEOIKIBE_01138	5.11e-222	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
LEOIKIBE_01139	8.55e-214	-	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LEOIKIBE_01140	0.0	-	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
LEOIKIBE_01141	1.32e-235	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
LEOIKIBE_01142	2.39e-314	-	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
LEOIKIBE_01143	6.62e-257	-	-	-	S	ko:K11744	-	ko00000	AI-2E family transporter
LEOIKIBE_01144	3.42e-157	gph	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
LEOIKIBE_01145	1.39e-295	-	-	-	E	-	-	-	Amino acid permease
LEOIKIBE_01146	6.45e-173	-	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiG
LEOIKIBE_01148	1.79e-201	-	-	-	S	-	-	-	SigmaW regulon antibacterial
LEOIKIBE_01149	1.36e-242	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LEOIKIBE_01151	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
LEOIKIBE_01152	0.0	-	-	-	P	-	-	-	Dimerisation domain of Zinc Transporter
LEOIKIBE_01153	5.84e-173	-	-	-	K	-	-	-	Transcriptional regulator
LEOIKIBE_01154	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LEOIKIBE_01155	1.63e-167	-	4.3.99.3	-	O	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LEOIKIBE_01156	8.01e-197	-	2.7.13.3	-	Q	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Transposase
LEOIKIBE_01157	0.0	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
LEOIKIBE_01158	1.55e-313	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
LEOIKIBE_01159	4.27e-251	-	-	-	E	-	-	-	Aminotransferase class-V
LEOIKIBE_01160	5.45e-234	-	-	-	S	-	-	-	Conserved hypothetical protein 698
LEOIKIBE_01161	1.82e-214	-	-	-	K	-	-	-	LysR substrate binding domain
LEOIKIBE_01164	4.25e-144	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
LEOIKIBE_01165	5.18e-06	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
LEOIKIBE_01166	4.43e-51	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
LEOIKIBE_01168	5.31e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LEOIKIBE_01169	1.95e-173	-	-	-	S	-	-	-	Lysin motif
LEOIKIBE_01170	3.5e-132	-	-	-	-	-	-	-	-
LEOIKIBE_01171	8.56e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
LEOIKIBE_01172	5.89e-173	coaX	2.7.1.33	-	K	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Type III pantothenate kinase
LEOIKIBE_01173	2.77e-272	-	-	-	M	-	-	-	Monogalactosyldiacylglycerol (MGDG) synthase
LEOIKIBE_01174	3.02e-227	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LEOIKIBE_01175	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
LEOIKIBE_01177	0.0	-	-	-	S	ko:K03307	-	ko00000	Sodium:solute symporter family
LEOIKIBE_01178	8.88e-284	-	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Galactokinase galactose-binding signature
LEOIKIBE_01179	0.0	-	-	-	M	-	-	-	Bacterial sugar transferase
LEOIKIBE_01180	7.33e-143	-	-	-	S	-	-	-	RNA recognition motif
LEOIKIBE_01181	5.88e-184	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
LEOIKIBE_01182	0.0	-	-	-	-	-	-	-	-
LEOIKIBE_01184	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
LEOIKIBE_01185	0.0	-	-	-	C	-	-	-	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein
LEOIKIBE_01186	2.83e-204	-	-	-	S	-	-	-	Domain of unknown function (DUF362)
LEOIKIBE_01187	1.49e-135	-	-	-	J	-	-	-	Putative rRNA methylase
LEOIKIBE_01188	8.54e-145	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LEOIKIBE_01189	3.73e-195	-	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
LEOIKIBE_01190	5.58e-289	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	NusA-like KH domain
LEOIKIBE_01191	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LEOIKIBE_01192	2e-82	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LEOIKIBE_01193	0.0	-	-	-	P	-	-	-	PA14 domain
LEOIKIBE_01194	3.57e-15	-	-	-	-	-	-	-	-
LEOIKIBE_01195	2.27e-150	-	-	-	-	-	-	-	-
LEOIKIBE_01196	0.0	-	-	-	T	-	-	-	5TM C-terminal transporter carbon starvation CstA
LEOIKIBE_01197	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
LEOIKIBE_01198	8.17e-135	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LEOIKIBE_01199	4.34e-284	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LEOIKIBE_01200	1.29e-187	-	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	2Fe-2S iron-sulfur cluster binding domain
LEOIKIBE_01201	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
LEOIKIBE_01202	4.83e-163	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	-
LEOIKIBE_01203	8.94e-56	-	-	-	-	-	-	-	-
LEOIKIBE_01204	1.43e-194	-	-	-	S	ko:K07051	-	ko00000	TatD related DNase
LEOIKIBE_01205	7.45e-49	XK27_09985	-	-	S	-	-	-	Protein of unknown function (DUF1232)
LEOIKIBE_01206	0.000935	-	-	-	-	-	-	-	-
LEOIKIBE_01207	1.15e-05	-	-	-	-	-	-	-	-
LEOIKIBE_01209	1.43e-11	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
LEOIKIBE_01210	9.13e-307	-	-	-	C	-	-	-	Sulfatase-modifying factor enzyme 1
LEOIKIBE_01211	7.37e-170	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
LEOIKIBE_01213	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
LEOIKIBE_01214	2.17e-08	-	-	-	M	-	-	-	major outer membrane lipoprotein
LEOIKIBE_01216	4.21e-137	-	-	-	J	ko:K05808	-	ko00000,ko03009	Sigma 54 modulation/S30EA ribosomal protein C terminus
LEOIKIBE_01218	8.88e-149	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Psort location CytoplasmicMembrane, score
LEOIKIBE_01219	9.82e-158	-	-	-	IQ	-	-	-	Short chain dehydrogenase
LEOIKIBE_01220	4.32e-296	-	-	-	C	-	-	-	Carboxymuconolactone decarboxylase family
LEOIKIBE_01221	6.54e-272	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
LEOIKIBE_01222	1.19e-185	-	-	-	S	-	-	-	Alpha/beta hydrolase family
LEOIKIBE_01223	2.85e-176	-	-	-	C	-	-	-	aldo keto reductase
LEOIKIBE_01224	1.05e-219	-	-	-	K	-	-	-	Transcriptional regulator
LEOIKIBE_01225	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
LEOIKIBE_01226	4.07e-305	-	-	-	C	-	-	-	4 iron, 4 sulfur cluster binding
LEOIKIBE_01227	1.88e-111	-	-	-	KT	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
LEOIKIBE_01228	8.66e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
LEOIKIBE_01229	2.67e-182	-	-	-	-	-	-	-	-
LEOIKIBE_01230	4.19e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
LEOIKIBE_01231	1.24e-51	-	-	-	-	-	-	-	-
LEOIKIBE_01233	1.46e-75	-	-	-	S	ko:K09954	-	ko00000	Putative quorum-sensing-regulated virulence factor
LEOIKIBE_01234	5.94e-178	-	4.2.99.20	-	I	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
LEOIKIBE_01235	1.69e-129	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
LEOIKIBE_01238	6.57e-174	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
LEOIKIBE_01239	2.63e-84	-	-	-	M	-	-	-	Lysin motif
LEOIKIBE_01240	3.45e-202	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
LEOIKIBE_01241	2.16e-267	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2219)
LEOIKIBE_01242	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
LEOIKIBE_01243	2.66e-06	-	-	-	-	-	-	-	-
LEOIKIBE_01245	0.0	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
LEOIKIBE_01246	2.4e-167	-	-	-	T	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
LEOIKIBE_01248	0.0	-	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LEOIKIBE_01249	0.0	-	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LEOIKIBE_01250	2.75e-130	-	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LEOIKIBE_01251	1.76e-79	-	-	-	S	-	-	-	PFAM Cupin 2 conserved barrel domain protein
LEOIKIBE_01252	4.3e-229	-	-	-	K	-	-	-	DNA-binding transcription factor activity
LEOIKIBE_01254	0.0	-	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	C-terminal, D2-small domain, of ClpB protein
LEOIKIBE_01255	6.21e-39	-	-	-	-	-	-	-	-
LEOIKIBE_01256	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LEOIKIBE_01258	9.83e-235	-	-	-	CO	-	-	-	Thioredoxin-like
LEOIKIBE_01259	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
LEOIKIBE_01260	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
LEOIKIBE_01261	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
LEOIKIBE_01262	7.63e-74	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
LEOIKIBE_01263	5.74e-211	ybfH	-	-	EG	-	-	-	spore germination
LEOIKIBE_01264	4.41e-137	-	-	-	-	-	-	-	-
LEOIKIBE_01265	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
LEOIKIBE_01266	3.62e-121	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LEOIKIBE_01267	7.48e-188	-	-	-	O	ko:K04083	-	ko00000,ko03110	Hsp33 protein
LEOIKIBE_01270	1.45e-233	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
LEOIKIBE_01277	2.22e-298	lpxK	2.7.1.130	-	M	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
LEOIKIBE_01278	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
LEOIKIBE_01279	2.13e-118	-	-	-	-	-	-	-	-
LEOIKIBE_01280	3.59e-229	-	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	prohibitin homologues
LEOIKIBE_01281	0.000103	-	-	-	S	-	-	-	Entericidin EcnA/B family
LEOIKIBE_01283	5.29e-206	-	1.4.1.16	-	S	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
LEOIKIBE_01284	1.76e-175	-	-	-	S	-	-	-	peptidoglycan biosynthetic process
LEOIKIBE_01285	1.88e-136	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated