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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HKICGBDN_00001	1.14e-279	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
HKICGBDN_00002	0.0	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HKICGBDN_00003	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	MreB/Mbl protein
HKICGBDN_00004	2.2e-61	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKICGBDN_00005	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKICGBDN_00006	5.31e-99	-	-	-	S	-	-	-	peptidase
HKICGBDN_00007	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HKICGBDN_00011	8.04e-298	-	-	-	-	-	-	-	-
HKICGBDN_00012	0.0	-	-	-	D	-	-	-	Chain length determinant protein
HKICGBDN_00013	9.65e-133	-	-	-	M	-	-	-	Polysaccharide biosynthesis/export protein
HKICGBDN_00015	4.46e-148	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKICGBDN_00016	1.67e-249	-	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
HKICGBDN_00017	3.33e-285	pgk	2.7.2.3	-	G	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HKICGBDN_00018	3.67e-236	-	-	-	-	-	-	-	-
HKICGBDN_00019	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	myo-inosose-2 dehydratase activity
HKICGBDN_00020	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
HKICGBDN_00021	0.0	-	-	-	L	-	-	-	TRCF
HKICGBDN_00022	2.29e-296	-	-	-	-	-	-	-	-
HKICGBDN_00023	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HKICGBDN_00024	3e-254	-	-	-	S	-	-	-	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HKICGBDN_00026	5.56e-214	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	PHP domain
HKICGBDN_00027	1.4e-259	-	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphate acetyl/butaryl transferase
HKICGBDN_00028	1.16e-241	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKICGBDN_00029	2.59e-75	-	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HKICGBDN_00033	1.33e-100	-	-	-	MP	-	-	-	regulation of cell-substrate adhesion
HKICGBDN_00037	0.0	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
HKICGBDN_00038	1.83e-231	-	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
HKICGBDN_00039	0.0	-	-	-	G	-	-	-	Glycogen debranching enzyme
HKICGBDN_00040	0.0	-	-	-	M	-	-	-	NPCBM/NEW2 domain
HKICGBDN_00041	0.0	-	-	-	M	ko:K04744	-	ko00000,ko02000	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HKICGBDN_00042	2.94e-155	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HKICGBDN_00043	2.51e-191	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HKICGBDN_00044	3.05e-169	-	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HKICGBDN_00045	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKICGBDN_00046	4.37e-124	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	adenylate kinase activity
HKICGBDN_00047	8.78e-167	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKICGBDN_00048	0.0	-	-	-	ET	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HKICGBDN_00050	2.9e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Semialdehyde dehydrogenase, NAD binding domain
HKICGBDN_00051	3.21e-306	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKICGBDN_00052	1.44e-110	-	-	-	S	-	-	-	Putative zinc- or iron-chelating domain
HKICGBDN_00053	7.7e-31	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HKICGBDN_00055	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	ATPases associated with a variety of cellular activities
HKICGBDN_00056	4e-147	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
HKICGBDN_00057	1.14e-126	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
HKICGBDN_00058	7.06e-249	-	-	-	-	-	-	-	-
HKICGBDN_00060	4.5e-176	-	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HKICGBDN_00061	3.65e-60	-	-	-	S	ko:K09131	-	ko00000	DUF167
HKICGBDN_00062	1.72e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKICGBDN_00063	9.85e-262	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKICGBDN_00064	4.47e-174	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKICGBDN_00065	2.96e-242	-	3.1.3.18	-	F	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HKICGBDN_00066	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HKICGBDN_00067	2.91e-228	-	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HKICGBDN_00068	0.0	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Peptidase S24-like
HKICGBDN_00069	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HKICGBDN_00070	6.29e-151	-	-	-	-	-	-	-	-
HKICGBDN_00071	5.95e-167	pks6	-	-	Q	-	-	-	amino acid activation for nonribosomal peptide biosynthetic process
HKICGBDN_00072	1.06e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF3485)
HKICGBDN_00073	1.19e-229	-	-	-	C	-	-	-	Transmembrane exosortase (Exosortase_EpsH)
HKICGBDN_00074	4.58e-220	prs	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKICGBDN_00075	5.05e-131	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HKICGBDN_00077	1.48e-141	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HKICGBDN_00078	1.31e-147	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKICGBDN_00079	1.56e-60	-	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S6
HKICGBDN_00080	2.97e-210	-	1.1.1.262	-	H	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal phosphate biosynthetic protein PdxA
HKICGBDN_00083	3.37e-224	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
HKICGBDN_00084	2.21e-254	-	2.7.1.11, 2.7.1.90	-	G	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Phosphofructokinase
HKICGBDN_00085	2.58e-256	-	-	-	L	-	-	-	Membrane
HKICGBDN_00086	6.18e-173	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	transporter
HKICGBDN_00087	2.92e-233	-	-	-	CO	-	-	-	Protein of unknown function, DUF255
HKICGBDN_00090	0.0	-	2.6.1.66	-	E	ko:K00835	ko00290,ko01100,ko01110,ko01130,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HKICGBDN_00091	4.1e-193	-	-	-	S	-	-	-	Domain of unknown function (DUF1732)
HKICGBDN_00092	4.39e-145	-	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
HKICGBDN_00093	0.0	-	-	-	P	-	-	-	Citrate transporter
HKICGBDN_00094	3.09e-208	-	-	-	J	ko:K01894	-	ko00000,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), catalytic domain
HKICGBDN_00097	3.1e-217	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HKICGBDN_00098	5.46e-170	-	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HKICGBDN_00100	1.12e-217	-	-	-	-	-	-	-	-
HKICGBDN_00101	3.17e-166	-	-	-	S	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
HKICGBDN_00102	9.03e-173	-	-	-	T	-	-	-	Outer membrane lipoprotein-sorting protein
HKICGBDN_00103	1.96e-226	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HKICGBDN_00104	0.0	secD	-	-	U	ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HKICGBDN_00106	1.62e-278	-	3.4.23.43	-	NOU	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
HKICGBDN_00107	2.38e-258	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
HKICGBDN_00108	2.95e-262	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKICGBDN_00109	4.19e-87	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HKICGBDN_00110	1.54e-217	-	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Acyl transferase domain
HKICGBDN_00112	1.63e-169	-	-	-	S	-	-	-	HAD-hyrolase-like
HKICGBDN_00113	3.06e-286	-	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
HKICGBDN_00114	1.21e-268	-	-	-	E	-	-	-	serine-type peptidase activity
HKICGBDN_00115	3.2e-305	-	-	-	M	-	-	-	OmpA family
HKICGBDN_00116	1.8e-215	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKICGBDN_00117	0.0	-	-	-	M	-	-	-	Peptidase M60-like family
HKICGBDN_00118	2.8e-295	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKICGBDN_00119	0.0	-	-	-	KT	-	-	-	Sigma factor PP2C-like phosphatases
HKICGBDN_00120	6.91e-165	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
HKICGBDN_00121	3.33e-242	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HKICGBDN_00123	2.01e-157	-	-	-	NU	ko:K02457,ko:K08084	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	protein transport across the cell outer membrane
HKICGBDN_00124	1.83e-188	-	-	-	-	-	-	-	-
HKICGBDN_00125	5.15e-247	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HKICGBDN_00126	3.43e-183	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HKICGBDN_00127	4.06e-244	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HKICGBDN_00128	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
HKICGBDN_00132	0.0	-	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HKICGBDN_00133	0.0	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKICGBDN_00134	9.26e-175	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
HKICGBDN_00135	1.7e-154	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	N-(5'phosphoribosyl)anthranilate (PRA) isomerase
HKICGBDN_00136	2.54e-287	-	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKICGBDN_00137	1.29e-186	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKICGBDN_00139	0.0	-	-	-	T	-	-	-	pathogenesis
HKICGBDN_00140	2.25e-91	-	-	-	O	-	-	-	response to oxidative stress
HKICGBDN_00141	1.6e-293	-	2.3.1.31	-	E	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko01000	alpha/beta hydrolase fold
HKICGBDN_00142	1.08e-63	-	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L36
HKICGBDN_00143	0.0	-	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Glycosyltransferase family 9 (heptosyltransferase)
HKICGBDN_00144	1.06e-188	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
HKICGBDN_00145	0.0	-	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HKICGBDN_00146	1.15e-188	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
HKICGBDN_00148	4.49e-187	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
HKICGBDN_00149	0.0	-	-	-	EG	-	-	-	BNR repeat-like domain
HKICGBDN_00150	0.0	legA	3.5.1.2	-	G	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	response to abiotic stimulus
HKICGBDN_00151	1.32e-195	supH	-	-	Q	-	-	-	phosphatase activity
HKICGBDN_00153	5.49e-85	nuoA	1.6.5.3	-	C	ko:K00330	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKICGBDN_00154	7.13e-276	-	-	-	G	-	-	-	Major Facilitator Superfamily
HKICGBDN_00158	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKICGBDN_00159	2.91e-38	-	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
HKICGBDN_00160	5.25e-79	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKICGBDN_00166	1.79e-77	-	-	-	M	-	-	-	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HKICGBDN_00167	6.05e-222	-	-	-	L	-	-	-	Transposase zinc-ribbon domain
HKICGBDN_00168	0.0	-	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Peptidase family M50
HKICGBDN_00171	0.0	-	-	-	L	-	-	-	UvrD/REP helicase N-terminal domain
HKICGBDN_00172	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HKICGBDN_00173	3.07e-211	MA20_36650	-	-	EG	-	-	-	spore germination
HKICGBDN_00174	3.57e-190	dpnC	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Dam-replacing family
HKICGBDN_00175	0.0	-	-	-	S	-	-	-	Alpha-2-macroglobulin family
HKICGBDN_00176	1.94e-289	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
HKICGBDN_00178	2.89e-123	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HKICGBDN_00181	1.79e-213	-	-	-	-	-	-	-	-
HKICGBDN_00182	3.97e-152	-	-	-	O	-	-	-	Glycoprotease family
HKICGBDN_00183	4.28e-274	-	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
HKICGBDN_00185	3.86e-112	-	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKICGBDN_00186	4.12e-139	-	-	-	L	-	-	-	RNase_H superfamily
HKICGBDN_00187	1.92e-102	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKICGBDN_00188	4.3e-44	-	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	RNA polymerase activity
HKICGBDN_00189	1.34e-135	-	5.4.99.20	-	J	ko:K06181	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HKICGBDN_00190	2.16e-188	-	-	-	-	-	-	-	-
HKICGBDN_00191	1.3e-104	-	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	NDK
HKICGBDN_00192	1.71e-201	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HKICGBDN_00193	4.12e-225	-	-	-	M	-	-	-	Glycosyl transferase family 2
HKICGBDN_00195	7.26e-285	-	-	-	NU	ko:K02653	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein F
HKICGBDN_00196	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II secretion system (T2SS), protein E, N-terminal domain
HKICGBDN_00197	0.0	-	-	-	NU	ko:K02652	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HKICGBDN_00198	4.22e-244	-	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKICGBDN_00199	2.83e-110	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
HKICGBDN_00200	3.86e-281	-	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HKICGBDN_00201	0.0	murJ	-	-	S	ko:K03980	-	ko00000,ko01011,ko02000	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HKICGBDN_00202	1.21e-269	-	-	-	IM	-	-	-	Cytidylyltransferase-like
HKICGBDN_00203	2.89e-156	-	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Iron/manganese superoxide dismutases, alpha-hairpin domain
HKICGBDN_00204	0.0	-	-	-	S	-	-	-	Glycosyl hydrolase-like 10
HKICGBDN_00205	4.2e-171	-	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HKICGBDN_00206	1.39e-190	-	-	-	L	ko:K06864	-	ko00000	tRNA processing
HKICGBDN_00207	3.77e-288	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HKICGBDN_00208	1.07e-238	-	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Polyprenyl synthetase
HKICGBDN_00209	0.0	-	-	-	E	ko:K03305	-	ko00000	POT family
HKICGBDN_00210	0.0	-	5.2.1.8	-	O	ko:K03770	-	ko00000,ko01000,ko03110	PPIC-type PPIASE domain
HKICGBDN_00211	2.39e-126	-	-	-	S	-	-	-	Pfam:DUF59
HKICGBDN_00212	7.43e-107	-	-	-	-	-	-	-	-
HKICGBDN_00214	8.93e-219	-	-	-	E	-	-	-	Domain of unknown function (DUF3472)
HKICGBDN_00215	9.04e-317	nuoN	1.6.5.3	-	C	ko:K00343	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKICGBDN_00216	0.0	-	1.6.5.3	-	C	ko:K00342	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Proton-conducting membrane transporter
HKICGBDN_00217	0.0	-	1.6.5.3	-	CP	ko:K00341	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus
HKICGBDN_00218	6.01e-61	nuoK	1.6.5.3	-	C	ko:K00340	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKICGBDN_00219	4.41e-156	-	1.6.5.3	-	C	ko:K00339	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone/plastoquinone oxidoreductase chain 6
HKICGBDN_00220	1.8e-124	nuoI	1.6.5.3	-	C	ko:K00338	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKICGBDN_00221	1.04e-309	nuoH	1.6.5.3	-	C	ko:K00337	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HKICGBDN_00222	0.0	-	1.6.5.3	-	C	ko:K00336	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region
HKICGBDN_00223	0.0	-	1.6.5.3	-	C	ko:K00335	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
HKICGBDN_00224	2.88e-142	-	1.6.5.3	-	C	ko:K00334	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Thioredoxin-like [2Fe-2S] ferredoxin
HKICGBDN_00225	4.39e-307	nuoD	1.6.5.3	-	C	ko:K00333	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKICGBDN_00227	0.0	-	-	-	G	-	-	-	Polysaccharide deacetylase
HKICGBDN_00228	0.0	-	-	-	P	-	-	-	Putative Na+/H+ antiporter
HKICGBDN_00229	1.07e-141	-	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Lumazine binding domain
HKICGBDN_00230	7.24e-205	-	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
HKICGBDN_00231	0.0	pmp21	-	-	T	-	-	-	pathogenesis
HKICGBDN_00232	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HKICGBDN_00234	0.0	-	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Uncharacterized protein family UPF0004
HKICGBDN_00235	0.0	-	-	-	-	ko:K07403	-	ko00000	-
HKICGBDN_00236	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKICGBDN_00237	0.0	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKICGBDN_00238	3.72e-187	-	3.4.13.22	-	M	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-ala-D-ala dipeptidase
HKICGBDN_00241	0.0	-	-	-	E	-	-	-	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKICGBDN_00242	0.0	-	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	tail specific protease
HKICGBDN_00244	3.14e-213	-	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
HKICGBDN_00245	0.0	-	3.6.4.13	-	L	ko:K03579	-	ko00000,ko01000	ATP-dependent helicase C-terminal
HKICGBDN_00246	0.0	-	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HKICGBDN_00247	3.39e-311	-	-	-	O	-	-	-	peroxiredoxin activity
HKICGBDN_00248	0.0	-	2.7.7.19	-	J	ko:K00970	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Poly A polymerase head domain
HKICGBDN_00249	0.0	-	-	-	G	-	-	-	Alpha amylase, catalytic domain
HKICGBDN_00250	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
HKICGBDN_00251	0.0	-	-	-	-	-	-	-	-
HKICGBDN_00252	7.21e-183	-	-	-	S	ko:K09778	-	ko00000	Domain of unknown function (DUF374)
HKICGBDN_00253	7.21e-203	folD	1.5.1.5, 3.5.4.9	-	H	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKICGBDN_00254	2.91e-182	-	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HKICGBDN_00255	2.62e-202	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKICGBDN_00256	4.88e-284	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HKICGBDN_00257	8.69e-261	-	-	-	J	ko:K05541	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKICGBDN_00258	1.31e-289	-	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	LytB protein
HKICGBDN_00260	2.34e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S20
HKICGBDN_00261	3.88e-140	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKICGBDN_00262	0.0	-	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HKICGBDN_00263	1.27e-220	-	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Phosphatidylserine decarboxylase
HKICGBDN_00264	1.1e-151	-	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3 epimerase family
HKICGBDN_00265	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Leucyl-tRNA synthetase, Domain 2
HKICGBDN_00266	0.0	-	-	-	P	-	-	-	Sulfatase
HKICGBDN_00268	7.45e-301	-	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase, C-terminal sheet domain
HKICGBDN_00269	0.0	-	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
HKICGBDN_00270	6.72e-268	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKICGBDN_00271	1.5e-161	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HKICGBDN_00272	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
HKICGBDN_00273	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HKICGBDN_00274	0.0	rarA	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
HKICGBDN_00275	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
HKICGBDN_00277	3.87e-301	-	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HKICGBDN_00278	8.21e-215	-	-	-	M	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HKICGBDN_00279	3.61e-268	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
HKICGBDN_00283	8.79e-263	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKICGBDN_00284	0.0	-	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	Type III restriction enzyme res subunit
HKICGBDN_00285	0.0	-	-	-	L	-	-	-	Type III restriction enzyme res subunit
HKICGBDN_00286	1.82e-126	cobU	2.7.1.156, 2.7.7.62, 6.3.5.10	-	H	ko:K02231,ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cobinamide kinase activity
HKICGBDN_00287	6.74e-207	-	-	-	G	-	-	-	myo-inosose-2 dehydratase activity
HKICGBDN_00288	6.59e-172	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HKICGBDN_00289	4.02e-239	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HKICGBDN_00290	9.28e-227	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HKICGBDN_00291	0.0	cobQ	-	-	H	-	-	-	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HKICGBDN_00293	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
HKICGBDN_00295	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKICGBDN_00296	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HKICGBDN_00297	3.85e-159	-	-	-	M	ko:K16079	-	ko00000,ko02000	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HKICGBDN_00298	2.34e-312	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HKICGBDN_00299	0.0	-	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKICGBDN_00300	5.53e-96	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
HKICGBDN_00301	8.04e-60	-	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	nucleotidyltransferase activity
HKICGBDN_00302	1.47e-229	-	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HKICGBDN_00303	0.0	-	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoglutarate dehydrogenase C-terminal
HKICGBDN_00304	1.48e-245	-	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit II
HKICGBDN_00305	0.0	-	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
HKICGBDN_00306	2.7e-113	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKICGBDN_00307	1.35e-106	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HKICGBDN_00308	0.0	-	-	-	T	-	-	-	Chase2 domain
HKICGBDN_00309	9.8e-232	-	2.7.1.221	-	S	ko:K07102	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Phosphotransferase enzyme family
HKICGBDN_00310	7.25e-307	-	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKICGBDN_00311	4.98e-92	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKICGBDN_00313	3.01e-113	-	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Ferritin-like domain
HKICGBDN_00314	0.0	-	-	-	-	-	-	-	-
HKICGBDN_00315	3.15e-103	-	-	-	J	-	-	-	YjgF/chorismate_mutase-like, putative endoribonuclease
HKICGBDN_00317	7.16e-115	-	-	-	S	ko:K03748	-	ko00000	DUF218 domain
HKICGBDN_00319	2.29e-229	-	-	-	S	-	-	-	mannose-ethanolamine phosphotransferase activity
HKICGBDN_00323	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RQC
HKICGBDN_00325	2.23e-176	-	-	-	-	-	-	-	-
HKICGBDN_00326	3.89e-209	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HKICGBDN_00327	2.18e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HKICGBDN_00328	6.3e-291	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKICGBDN_00329	2.23e-205	-	-	-	S	ko:K03453	-	ko00000	Bile acid
HKICGBDN_00332	6.39e-71	-	-	-	-	-	-	-	-
HKICGBDN_00333	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKICGBDN_00334	0.0	-	2.3.1.40, 6.2.1.20	-	IQ	ko:K05939	ko00071,ko00564,map00071,map00564	ko00000,ko00001,ko01000	AMP-binding enzyme
HKICGBDN_00335	2.84e-41	-	-	-	T	-	-	-	pathogenesis
HKICGBDN_00336	5.39e-136	-	-	-	F	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HKICGBDN_00337	8.36e-174	-	-	-	S	-	-	-	peptidoglycan biosynthetic process
HKICGBDN_00338	6.18e-205	-	1.4.1.16	-	S	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HKICGBDN_00340	0.000103	-	-	-	S	-	-	-	Entericidin EcnA/B family
HKICGBDN_00341	1.99e-233	-	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	prohibitin homologues
HKICGBDN_00342	2.13e-118	-	-	-	-	-	-	-	-
HKICGBDN_00343	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
HKICGBDN_00344	2.22e-298	lpxK	2.7.1.130	-	M	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
HKICGBDN_00345	1.94e-140	-	-	-	S	ko:K07164	-	ko00000	C4-type zinc ribbon domain
HKICGBDN_00346	2.24e-264	-	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
HKICGBDN_00347	3.03e-74	-	-	-	-	-	-	-	-
HKICGBDN_00348	1.97e-189	-	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	MazG nucleotide pyrophosphohydrolase domain
HKICGBDN_00349	2.92e-70	-	-	-	-	-	-	-	-
HKICGBDN_00350	2.51e-182	-	-	-	S	-	-	-	competence protein
HKICGBDN_00351	6.79e-100	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HKICGBDN_00354	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Sulfatase
HKICGBDN_00355	2.63e-143	-	-	-	-	-	-	-	-
HKICGBDN_00356	1.06e-163	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HKICGBDN_00357	4.82e-178	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKICGBDN_00358	2.6e-298	-	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	16S rRNA methyltransferase RsmB/F
HKICGBDN_00359	9.36e-114	-	3.1.6.8	-	P	ko:K01134	ko00600,ko04142,map00600,map04142	ko00000,ko00001,ko01000	COG3119 Arylsulfatase A
HKICGBDN_00360	2.9e-316	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Arginosuccinate synthase
HKICGBDN_00362	2.79e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKICGBDN_00363	8.43e-59	-	-	-	S	-	-	-	Zinc ribbon domain
HKICGBDN_00364	4.77e-310	-	-	-	S	-	-	-	PFAM CBS domain containing protein
HKICGBDN_00365	2.51e-151	-	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
HKICGBDN_00366	4.83e-82	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
HKICGBDN_00368	1.67e-177	-	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Indole-3-glycerol phosphate synthase
HKICGBDN_00369	3.4e-229	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
HKICGBDN_00370	1.39e-157	-	-	-	S	-	-	-	3D domain
HKICGBDN_00371	2.15e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKICGBDN_00372	9.91e-171	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HKICGBDN_00373	1.65e-113	aglS	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
HKICGBDN_00374	4.52e-101	exbD2	-	-	U	ko:K03559	-	ko00000,ko02000	biopolymer transport protein
HKICGBDN_00376	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKICGBDN_00377	5.47e-195	-	-	-	-	-	-	-	-
HKICGBDN_00378	8.99e-277	-	-	-	K	-	-	-	sequence-specific DNA binding
HKICGBDN_00379	0.0	-	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	Ribonuclease E/G family
HKICGBDN_00380	5.06e-236	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Actin
HKICGBDN_00381	0.0	lacZ_17	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HKICGBDN_00383	2.24e-263	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HKICGBDN_00385	7.5e-177	-	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
HKICGBDN_00386	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
HKICGBDN_00387	2.26e-115	-	-	-	-	-	-	-	-
HKICGBDN_00388	1.89e-166	-	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	SAICAR synthetase
HKICGBDN_00389	0.0	-	-	-	K	-	-	-	Transcription elongation factor, N-terminal
HKICGBDN_00390	0.0	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKICGBDN_00391	1.05e-180	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKICGBDN_00392	6.75e-305	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKICGBDN_00393	1.34e-201	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase, N-terminal
HKICGBDN_00394	1.06e-109	-	-	-	S	ko:K15977	-	ko00000	DoxX
HKICGBDN_00395	2.76e-292	-	4.2.1.129, 5.4.99.17	-	I	ko:K06045	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
HKICGBDN_00396	4.7e-193	-	-	-	-	-	-	-	-
HKICGBDN_00397	1.18e-224	-	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
HKICGBDN_00398	9.39e-183	-	-	-	H	-	-	-	ThiF family
HKICGBDN_00399	3.67e-126	-	-	-	U	-	-	-	response to pH
HKICGBDN_00400	2.89e-223	-	-	-	-	-	-	-	-
HKICGBDN_00401	4.09e-218	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKICGBDN_00403	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
HKICGBDN_00404	3.11e-271	-	-	-	S	-	-	-	COGs COG4299 conserved
HKICGBDN_00405	5.1e-153	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKICGBDN_00406	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein dimerisation domain
HKICGBDN_00407	0.0	-	-	-	-	-	-	-	-
HKICGBDN_00408	6.27e-219	-	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	ATP synthase A chain
HKICGBDN_00409	1.65e-11	-	-	-	S	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	PFAM H transporting two-sector ATPase C subunit
HKICGBDN_00410	4.38e-78	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase B/B' CF(0)
HKICGBDN_00411	6.46e-86	-	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase delta (OSCP) subunit
HKICGBDN_00412	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKICGBDN_00413	4.5e-201	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKICGBDN_00414	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKICGBDN_00415	1.24e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HKICGBDN_00416	1.38e-139	-	-	-	-	-	-	-	-
HKICGBDN_00417	8.17e-124	sprT	-	-	K	-	-	-	SprT-like family
HKICGBDN_00418	4.27e-275	-	-	-	S	-	-	-	COGs COG4299 conserved
HKICGBDN_00419	7.67e-285	-	2.6.1.59	-	M	ko:K02805	-	ko00000,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HKICGBDN_00420	4.94e-114	flmH	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKICGBDN_00421	7.63e-220	-	-	-	M	-	-	-	Glycosyl transferase family 2
HKICGBDN_00422	1.08e-73	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
HKICGBDN_00423	1.85e-75	-	-	-	P	ko:K03297,ko:K11741	-	ko00000,ko02000	Multidrug Resistance protein
HKICGBDN_00426	0.0	-	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HKICGBDN_00427	2.93e-233	-	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Biotin and Thiamin Synthesis associated domain
HKICGBDN_00428	0.0	-	-	-	P	-	-	-	Sulfatase
HKICGBDN_00429	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
HKICGBDN_00430	2.6e-296	-	-	-	O	ko:K09015	-	ko00000	Uncharacterized protein family (UPF0051)
HKICGBDN_00431	0.0	-	-	-	O	ko:K09014	-	ko00000	Uncharacterized protein family (UPF0051)
HKICGBDN_00432	8.34e-178	-	-	-	O	ko:K09013	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
HKICGBDN_00433	6.78e-100	-	-	-	P	ko:K09825	-	ko00000,ko03000	Ferric uptake regulator family
HKICGBDN_00434	2.14e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
HKICGBDN_00435	1.93e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal prokaryotic L21 protein
HKICGBDN_00436	1.65e-106	-	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
HKICGBDN_00437	1.07e-199	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HKICGBDN_00439	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HKICGBDN_00440	0.0	-	-	-	-	-	-	-	-
HKICGBDN_00441	2.58e-225	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HKICGBDN_00443	1.36e-175	-	-	-	-	-	-	-	-
HKICGBDN_00444	3.35e-131	-	-	-	L	-	-	-	Conserved hypothetical protein 95
HKICGBDN_00445	1.18e-309	-	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
HKICGBDN_00446	9.68e-226	-	-	-	S	-	-	-	Aspartyl protease
HKICGBDN_00447	1.67e-272	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKICGBDN_00448	2.4e-160	-	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	DNA / pantothenate metabolism flavoprotein
HKICGBDN_00449	9.7e-279	-	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
HKICGBDN_00450	1.94e-104	-	-	-	K	ko:K03826	-	ko00000,ko01000	acetyltransferase
HKICGBDN_00451	2.48e-173	-	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HKICGBDN_00452	0.0	-	-	-	L	-	-	-	Polyphosphate kinase 2 (PPK2)
HKICGBDN_00453	0.0	-	-	-	S	-	-	-	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
HKICGBDN_00454	2.31e-259	-	-	-	M	-	-	-	Peptidase family M23
HKICGBDN_00456	8.37e-126	-	4.1.1.36	-	H	ko:K01598	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Flavoprotein
HKICGBDN_00457	1.31e-81	-	-	-	DJ	-	-	-	Addiction module toxin, RelE StbE family
HKICGBDN_00458	2.34e-208	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HKICGBDN_00460	1.26e-139	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
HKICGBDN_00461	0.0	-	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKICGBDN_00462	4.75e-245	-	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR synthase related protein, N-terminal domain
HKICGBDN_00463	1.84e-105	-	-	-	S	ko:K15977	-	ko00000	DoxX
HKICGBDN_00464	9.94e-243	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HKICGBDN_00465	0.0	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
HKICGBDN_00466	1.02e-174	-	-	-	-	-	-	-	-
HKICGBDN_00467	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DbpA RNA binding domain
HKICGBDN_00468	0.0	-	-	-	P	ko:K01138	-	ko00000,ko01000	PA14 domain
HKICGBDN_00469	6.18e-150	-	-	-	L	-	-	-	Membrane
HKICGBDN_00471	0.0	gcvP	1.4.4.2	-	E	ko:K00281	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HKICGBDN_00472	6.67e-86	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HKICGBDN_00473	2.85e-267	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Aminomethyltransferase folate-binding domain
HKICGBDN_00474	1.11e-261	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKICGBDN_00475	9.59e-216	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HKICGBDN_00476	6.26e-269	-	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
HKICGBDN_00477	1.21e-268	-	-	-	M	-	-	-	Glycosyl transferase 4-like
HKICGBDN_00478	1.18e-224	-	-	-	M	ko:K07276	-	ko00000	Mitochondrial fission ELM1
HKICGBDN_00479	1.59e-269	-	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
HKICGBDN_00480	1.11e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKICGBDN_00481	2.11e-121	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKICGBDN_00482	4.36e-142	-	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S4/S9 N-terminal domain
HKICGBDN_00483	4.02e-191	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
HKICGBDN_00487	4.37e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKICGBDN_00488	0.0	-	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
HKICGBDN_00489	7.21e-290	-	3.5.1.42	-	S	ko:K03742	ko00760,map00760	ko00000,ko00001,ko01000	Competence-damaged protein
HKICGBDN_00490	5.7e-153	-	-	-	O	-	-	-	methyltransferase activity
HKICGBDN_00491	1.6e-182	-	-	-	U	ko:K20276	ko02024,map02024	ko00000,ko00001	domain, Protein
HKICGBDN_00492	0.0	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
HKICGBDN_00493	6.16e-261	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Elongator protein 3, MiaB family, Radical SAM
HKICGBDN_00494	1.1e-197	-	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SRP54-type protein, GTPase domain
HKICGBDN_00495	8.13e-206	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKICGBDN_00496	8.55e-104	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HKICGBDN_00497	9.59e-288	-	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase II
HKICGBDN_00498	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (E and Q), anti-codon binding domain
HKICGBDN_00499	0.0	-	-	-	-	-	-	-	-
HKICGBDN_00500	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HKICGBDN_00501	5.67e-258	-	-	-	S	-	-	-	ankyrin repeats
HKICGBDN_00502	1.05e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HKICGBDN_00503	1.06e-44	-	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S21
HKICGBDN_00504	0.0	-	2.7.1.167, 2.7.7.70	-	M	ko:K03272	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	pfkB family carbohydrate kinase
HKICGBDN_00505	8.25e-131	-	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
HKICGBDN_00506	6.23e-118	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Polynucleotide kinase 3 phosphatase
HKICGBDN_00507	4.48e-223	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
HKICGBDN_00509	6.06e-251	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
HKICGBDN_00510	5.69e-190	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKICGBDN_00511	1.2e-196	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKICGBDN_00512	5.68e-188	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HKICGBDN_00513	1.48e-120	-	-	-	M	ko:K06142	-	ko00000	Outer membrane protein (OmpH-like)
HKICGBDN_00514	3.42e-196	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HKICGBDN_00515	6.38e-151	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKICGBDN_00516	6.25e-144	-	-	-	-	-	-	-	-
HKICGBDN_00517	4.86e-201	-	-	-	S	-	-	-	DisA bacterial checkpoint controller nucleotide-binding
HKICGBDN_00519	6.94e-153	-	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	AAA domain
HKICGBDN_00520	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
HKICGBDN_00521	0.0	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HKICGBDN_00522	1.16e-178	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HKICGBDN_00523	1.33e-174	-	-	-	NU	-	-	-	Prepilin-type N-terminal cleavage methylation domain
HKICGBDN_00525	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	PFAM coagulation factor 5 8 type domain protein
HKICGBDN_00526	9.86e-168	-	-	-	M	-	-	-	Peptidase family M23
HKICGBDN_00527	1.04e-144	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKICGBDN_00528	7.54e-201	-	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKICGBDN_00531	0.0	-	-	-	S	-	-	-	Terminase
HKICGBDN_00532	2.46e-215	-	-	-	D	ko:K19234,ko:K19236	ko01503,map01503	ko00000,ko00001,ko01002,ko01011	ErfK ybiS ycfS ynhG family protein
HKICGBDN_00533	2.32e-151	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKICGBDN_00534	3.01e-49	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal_S15
HKICGBDN_00535	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HKICGBDN_00536	9.05e-313	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	PFAM CBS domain containing protein
HKICGBDN_00537	3.4e-311	-	-	-	S	-	-	-	PFAM CBS domain containing protein
HKICGBDN_00538	0.0	-	-	-	C	-	-	-	Cytochrome c554 and c-prime
HKICGBDN_00539	1.63e-164	-	-	-	CO	-	-	-	Thioredoxin-like
HKICGBDN_00540	1.1e-159	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKICGBDN_00541	4.7e-156	-	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase
HKICGBDN_00542	4.25e-238	pyrD	1.3.5.2	-	F	ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
HKICGBDN_00543	0.0	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase alpha chain like domain
HKICGBDN_00544	5.21e-142	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKICGBDN_00545	0.0	-	4.1.1.15	-	E	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase conserved domain
HKICGBDN_00546	0.0	-	-	-	-	-	-	-	-
HKICGBDN_00548	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	PFAM Glycoside hydrolase, family 20, catalytic core
HKICGBDN_00550	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HKICGBDN_00551	0.0	-	-	-	KT	ko:K02584	ko02020,map02020	ko00000,ko00001,ko03000	Bacterial regulatory protein, Fis family
HKICGBDN_00552	9.68e-221	-	2.5.1.21	-	I	ko:K00801	ko00100,ko00909,ko01100,ko01110,ko01130,map00100,map00909,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01006	Squalene/phytoene synthase
HKICGBDN_00553	0.0	-	-	-	S	-	-	-	Fungal chitosanase of glycosyl hydrolase group 75
HKICGBDN_00554	3.14e-192	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
HKICGBDN_00555	8.38e-98	-	-	-	-	-	-	-	-
HKICGBDN_00556	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
HKICGBDN_00559	9.85e-147	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HKICGBDN_00563	1.85e-302	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	efflux transmembrane transporter activity
HKICGBDN_00566	4.36e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Enoyl-CoA hydratase/isomerase
HKICGBDN_00567	6.38e-258	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
HKICGBDN_00569	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKICGBDN_00570	4.69e-79	rsfS	-	-	S	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKICGBDN_00571	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKICGBDN_00572	7.58e-140	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease
HKICGBDN_00573	1.14e-175	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKICGBDN_00574	0.0	-	-	-	CO	-	-	-	Disulphide bond corrector protein DsbC
HKICGBDN_00575	1.86e-94	-	-	-	O	-	-	-	OsmC-like protein
HKICGBDN_00577	3.42e-111	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
HKICGBDN_00578	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
HKICGBDN_00580	2.52e-205	-	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
HKICGBDN_00581	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB dependent receptor
HKICGBDN_00582	4.97e-168	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKICGBDN_00583	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKICGBDN_00585	3.07e-155	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HKICGBDN_00586	2.05e-229	-	-	-	EP	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HKICGBDN_00587	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal
HKICGBDN_00588	9.67e-251	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Predicted permease YjgP/YjgQ family
HKICGBDN_00589	2.31e-127	-	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Recombination protein O N terminal
HKICGBDN_00590	3.99e-183	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKICGBDN_00591	0.0	dxs	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKICGBDN_00592	3.08e-52	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
HKICGBDN_00593	0.0	-	-	-	O	-	-	-	C-terminal four TMM region of protein-O-mannosyltransferase
HKICGBDN_00594	0.0	-	-	-	T	-	-	-	Bacterial regulatory protein, Fis family
HKICGBDN_00595	1.82e-274	-	-	-	T	-	-	-	PAS domain
HKICGBDN_00596	3.37e-97	-	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase superfamily
HKICGBDN_00597	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	BPG-independent PGAM N-terminus (iPGM_N)
HKICGBDN_00598	4.16e-85	-	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S12/S23
HKICGBDN_00599	2.91e-104	-	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S7p/S5e
HKICGBDN_00600	0.0	-	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKICGBDN_00601	3.67e-65	-	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S10p/S20e
HKICGBDN_00602	3.86e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKICGBDN_00603	1.9e-131	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L4/L1 family
HKICGBDN_00604	8.72e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKICGBDN_00605	1.85e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKICGBDN_00606	1.05e-58	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKICGBDN_00607	4.05e-152	-	-	-	-	-	-	-	-
HKICGBDN_00608	4.97e-70	-	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome
HKICGBDN_00609	5.2e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKICGBDN_00610	3.42e-97	-	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKICGBDN_00611	2.36e-34	-	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L29 protein
HKICGBDN_00612	2.19e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKICGBDN_00613	6.79e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKICGBDN_00614	6.2e-203	-	-	-	-	-	-	-	-
HKICGBDN_00615	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKICGBDN_00616	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF4982)
HKICGBDN_00617	2.73e-263	-	5.2.1.8	-	O	ko:K03771	-	ko00000,ko01000,ko03110	SurA N-terminal domain
HKICGBDN_00618	3.02e-170	-	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HKICGBDN_00619	1.67e-141	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HKICGBDN_00625	1.9e-62	-	-	-	L	-	-	-	bacterial (prokaryotic) histone like domain
HKICGBDN_00626	1.71e-207	-	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HII
HKICGBDN_00627	5.96e-127	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
HKICGBDN_00628	4.32e-174	-	-	-	F	-	-	-	NUDIX domain
HKICGBDN_00629	1.42e-149	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Putative methyltransferase
HKICGBDN_00630	1.39e-282	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKICGBDN_00631	5.64e-66	-	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
HKICGBDN_00632	6.5e-186	-	-	-	DTZ	-	-	-	EF-hand, calcium binding motif
HKICGBDN_00633	1.31e-214	-	-	-	L	ko:K03733	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HKICGBDN_00634	1.46e-07	-	-	-	E	-	-	-	LysE type translocator
HKICGBDN_00636	9.56e-51	-	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Ribosomal protein S16
HKICGBDN_00637	1.55e-128	aroK	2.7.1.71	-	E	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKICGBDN_00638	6.97e-241	-	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKICGBDN_00639	1.16e-78	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
HKICGBDN_00640	4.98e-117	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HKICGBDN_00641	2.73e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HKICGBDN_00642	1.22e-246	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKICGBDN_00643	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
HKICGBDN_00644	3.35e-116	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKICGBDN_00649	0.0	-	-	-	CO	-	-	-	Thioredoxin-like
HKICGBDN_00657	0.0	-	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HKICGBDN_00658	3.36e-130	-	-	-	D	ko:K06287	-	ko00000	Maf-like protein
HKICGBDN_00659	2.66e-290	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKICGBDN_00661	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HKICGBDN_00662	0.0	-	-	-	GK	-	-	-	carbohydrate kinase activity
HKICGBDN_00663	4.34e-202	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKICGBDN_00664	1.21e-209	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HKICGBDN_00665	0.0	-	-	-	I	-	-	-	Acetyltransferase (GNAT) domain
HKICGBDN_00666	2.3e-142	-	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Cytidylate kinase
HKICGBDN_00667	8.17e-147	-	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HKICGBDN_00668	1.57e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKICGBDN_00669	1.53e-120	actI	1.5.1.36	-	S	ko:K00484	ko00350,ko00740,ko01100,ko01120,ko01220,map00350,map00740,map01100,map01120,map01220	ko00000,ko00001,ko01000	FMN binding
HKICGBDN_00670	3.86e-162	rnc	3.1.26.3	-	K	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKICGBDN_00671	0.0	-	-	-	P	ko:K07221	-	ko00000,ko02000	Phosphate-selective porin O and P
HKICGBDN_00672	2.72e-18	-	-	-	-	-	-	-	-
HKICGBDN_00673	3.23e-182	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HKICGBDN_00674	4.14e-164	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Tetrapyrrole (Corrin/Porphyrin) Methylases
HKICGBDN_00675	7.51e-116	-	-	-	S	-	-	-	Lipopolysaccharide-assembly
HKICGBDN_00676	1.18e-170	-	-	-	S	ko:K05807	-	ko00000,ko02000	Outer membrane lipoprotein
HKICGBDN_00677	2.88e-116	hisI	3.5.4.19	-	E	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-AMP cyclohydrolase
HKICGBDN_00678	3.12e-224	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
HKICGBDN_00679	4.91e-121	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	G/U mismatch-specific uracil-DNA glycosylase activity
HKICGBDN_00680	6.13e-194	-	-	-	-	-	-	-	-
HKICGBDN_00681	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HKICGBDN_00682	3.15e-137	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
HKICGBDN_00684	7.18e-182	-	-	-	Q	-	-	-	methyltransferase activity
HKICGBDN_00685	0.0	-	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	NAD synthase
HKICGBDN_00686	2.28e-79	-	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HKICGBDN_00688	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	exo-alpha-(2->6)-sialidase activity
HKICGBDN_00689	8.38e-276	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
HKICGBDN_00690	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR/Asp-box repeat
HKICGBDN_00691	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HKICGBDN_00697	1.09e-09	-	-	-	K	-	-	-	transcriptional
HKICGBDN_00701	3.4e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKICGBDN_00702	9.5e-239	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKICGBDN_00703	1.83e-282	-	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKICGBDN_00704	1.27e-207	MA20_42350	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyl transferase, family 2
HKICGBDN_00705	3.78e-248	-	-	-	M	-	-	-	Glycosyl transferase, family 2
HKICGBDN_00706	5.94e-235	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HKICGBDN_00708	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
HKICGBDN_00709	2.21e-264	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HKICGBDN_00710	6.03e-270	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKICGBDN_00711	1.77e-142	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HKICGBDN_00712	4.96e-271	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HKICGBDN_00713	2.94e-184	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HKICGBDN_00714	1.24e-195	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKICGBDN_00715	2.72e-263	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKICGBDN_00716	7.91e-305	mnmE	-	-	J	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKICGBDN_00717	6.74e-138	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HKICGBDN_00718	3.95e-13	-	-	-	S	-	-	-	Mac 1
HKICGBDN_00719	2.82e-154	-	-	-	S	-	-	-	UPF0126 domain
HKICGBDN_00720	5.27e-189	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HKICGBDN_00721	4.54e-105	-	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HKICGBDN_00722	0.0	rsmH	2.1.1.199	-	M	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKICGBDN_00724	0.0	-	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein dimerisation domain
HKICGBDN_00725	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKICGBDN_00726	0.0	-	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Mur ligase middle domain
HKICGBDN_00727	8.1e-261	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKICGBDN_00728	2.48e-315	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKICGBDN_00729	8.21e-160	mltD	-	CBM50	M	ko:K08307,ko:K12204,ko:K19224	-	ko00000,ko01000,ko01002,ko01011,ko02044	LysM domain
HKICGBDN_00730	1.33e-277	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Cell cycle protein
HKICGBDN_00731	3.91e-267	-	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKICGBDN_00732	0.0	murB	-	-	M	-	-	-	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain
HKICGBDN_00733	4.13e-228	ddl	6.3.2.4	-	M	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	D-ala D-ala ligase N-terminus
HKICGBDN_00734	1.8e-216	-	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	POTRA domain, FtsQ-type
HKICGBDN_00735	1.15e-238	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKICGBDN_00736	1.92e-238	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
HKICGBDN_00737	7.14e-141	-	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HKICGBDN_00738	0.0	-	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase family (aconitate hydratase)
HKICGBDN_00739	1.53e-146	-	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
HKICGBDN_00740	4.99e-274	-	-	-	-	-	-	-	-
HKICGBDN_00741	0.0	-	-	-	O	-	-	-	Trypsin
HKICGBDN_00742	0.0	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HKICGBDN_00743	4.53e-284	-	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate synthase
HKICGBDN_00744	2.65e-174	-	-	-	E	-	-	-	ATPases associated with a variety of cellular activities
HKICGBDN_00745	7.15e-199	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKICGBDN_00746	5.88e-163	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S2
HKICGBDN_00747	9.04e-171	cbiX	4.99.1.3	-	S	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	sirohydrochlorin cobaltochelatase activity
HKICGBDN_00748	6.68e-198	-	2.5.1.55	-	M	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	DAHP synthetase I family
HKICGBDN_00751	6.31e-171	-	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKICGBDN_00752	6.55e-221	-	-	-	E	-	-	-	Phosphoserine phosphatase
HKICGBDN_00753	0.0	-	6.3.2.45	-	M	ko:K02558	-	ko00000,ko01000	Mur ligase family, catalytic domain
HKICGBDN_00754	3.11e-306	-	-	-	M	-	-	-	OmpA family
HKICGBDN_00755	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
HKICGBDN_00756	9.27e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HKICGBDN_00757	5.33e-114	ywrF	-	-	S	-	-	-	FMN binding
HKICGBDN_00758	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKICGBDN_00759	0.0	-	-	-	T	-	-	-	pathogenesis
HKICGBDN_00761	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
HKICGBDN_00762	5.48e-296	-	-	-	-	-	-	-	-
HKICGBDN_00763	5.12e-71	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HKICGBDN_00765	1.1e-160	-	-	-	S	-	-	-	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HKICGBDN_00766	9.82e-262	-	-	-	M	ko:K02022	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKICGBDN_00767	8.42e-302	-	4.2.1.129, 5.4.99.17, 5.5.1.16	-	I	ko:K06045,ko:K17811	ko00909,ko01110,map00909,map01110	ko00000,ko00001,ko01000	PFAM Prenyltransferase squalene oxidase
HKICGBDN_00768	0.0	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
HKICGBDN_00769	1.72e-294	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HKICGBDN_00770	4.87e-288	-	3.2.1.23	-	M	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HKICGBDN_00773	2.21e-215	-	-	-	K	-	-	-	LysR substrate binding domain
HKICGBDN_00774	5.45e-234	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HKICGBDN_00775	7.38e-252	-	-	-	E	-	-	-	Aminotransferase class-V
HKICGBDN_00776	2.56e-312	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
HKICGBDN_00777	0.0	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HKICGBDN_00778	2.2e-173	-	2.7.13.3	-	Q	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Transposase
HKICGBDN_00779	6.66e-167	-	4.3.99.3	-	O	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HKICGBDN_00780	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKICGBDN_00781	1.67e-172	-	-	-	K	-	-	-	Transcriptional regulator
HKICGBDN_00782	0.0	-	-	-	P	-	-	-	Dimerisation domain of Zinc Transporter
HKICGBDN_00783	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
HKICGBDN_00785	1.93e-242	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKICGBDN_00786	2.17e-201	-	-	-	S	-	-	-	SigmaW regulon antibacterial
HKICGBDN_00788	4.07e-173	-	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiG
HKICGBDN_00789	3.27e-294	-	-	-	E	-	-	-	Amino acid permease
HKICGBDN_00790	3.28e-155	gph	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
HKICGBDN_00791	6.62e-257	-	-	-	S	ko:K11744	-	ko00000	AI-2E family transporter
HKICGBDN_00792	2.39e-314	-	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-dependent decarboxylase, pyridoxal binding domain
HKICGBDN_00793	7.64e-235	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HKICGBDN_00794	0.0	-	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
HKICGBDN_00795	3.48e-213	-	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HKICGBDN_00796	5.11e-222	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
HKICGBDN_00797	1.56e-127	-	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKICGBDN_00798	7.86e-138	-	-	-	T	-	-	-	histone H2A K63-linked ubiquitination
HKICGBDN_00800	3.23e-253	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKICGBDN_00801	2.84e-286	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HKICGBDN_00802	1.89e-255	-	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HKICGBDN_00803	4.88e-265	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HKICGBDN_00812	1.9e-21	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HKICGBDN_00813	0.0	-	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HKICGBDN_00814	0.0	hyl	2.3.1.48, 3.2.1.169, 3.2.1.35	GH84	G	ko:K01197,ko:K15719	ko00531,ko01100,ko04931,map00531,map01100,map04931	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylhexosaminidase activity
HKICGBDN_00815	4.14e-229	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HKICGBDN_00816	2.47e-101	-	-	-	-	-	-	-	-
HKICGBDN_00817	2.15e-192	-	-	-	P	ko:K09820	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKICGBDN_00818	6.95e-183	-	-	-	P	ko:K09819	-	ko00000,ko00002,ko02000	FecCD transport family
HKICGBDN_00819	5.46e-126	-	-	-	S	ko:K19411	-	ko00000	UvrB/uvrC motif
HKICGBDN_00820	2.26e-243	-	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	ATP:guanido phosphotransferase, C-terminal catalytic domain
HKICGBDN_00821	0.0	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HKICGBDN_00822	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-L-fucosidase
HKICGBDN_00823	1.93e-63	-	-	-	P	ko:K03972	-	ko00000	Rhodanese Homology Domain
HKICGBDN_00824	2.1e-201	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
HKICGBDN_00825	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	HMGL-like
HKICGBDN_00826	1.28e-223	-	-	-	CO	-	-	-	amine dehydrogenase activity
HKICGBDN_00827	8.39e-89	-	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HKICGBDN_00828	2.05e-163	-	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
HKICGBDN_00829	7.55e-206	-	-	-	GM	-	-	-	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKICGBDN_00830	2.41e-232	-	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (W and Y)
HKICGBDN_00831	1.56e-103	-	-	-	T	-	-	-	Universal stress protein family
HKICGBDN_00832	1.45e-190	-	-	-	S	ko:K09769	-	ko00000	YmdB-like protein
HKICGBDN_00833	4.13e-184	-	-	-	H	ko:K22132	-	ko00000,ko03016	ThiF family
HKICGBDN_00834	9.9e-121	-	-	-	-	-	-	-	-
HKICGBDN_00836	1.12e-229	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HKICGBDN_00837	3.22e-124	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HKICGBDN_00838	3.77e-289	kbl	2.3.1.29	-	E	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HKICGBDN_00839	0.0	-	-	-	KLT	-	-	-	Sulfatase-modifying factor enzyme 1
HKICGBDN_00840	1.06e-182	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
HKICGBDN_00841	0.0	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
HKICGBDN_00850	1.5e-30	-	-	-	M	-	-	-	D-alanyl-D-alanine carboxypeptidase
HKICGBDN_00868	2.62e-21	-	-	-	OU	-	-	-	Serine dehydrogenase proteinase
HKICGBDN_00873	4.01e-71	-	-	-	S	-	-	-	Phage terminase large subunit (GpA)
HKICGBDN_00875	7.88e-98	-	-	-	D	-	-	-	Filamentation induced by cAMP protein fic
HKICGBDN_00886	1.04e-54	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
HKICGBDN_00887	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKICGBDN_00888	0.0	-	-	-	M	ko:K02847,ko:K13009,ko:K16705	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
HKICGBDN_00889	8.67e-85	-	-	-	S	-	-	-	Protein of unknown function, DUF488
HKICGBDN_00890	3.43e-234	-	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Porphobilinogen deaminase, dipyromethane cofactor binding domain
HKICGBDN_00891	1.07e-240	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Glutamyl-tRNAGlu reductase, N-terminal domain
HKICGBDN_00892	1.02e-178	-	-	-	S	-	-	-	Cytochrome C assembly protein
HKICGBDN_00893	3.84e-189	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Type I GTP cyclohydrolase folE2
HKICGBDN_00894	4.52e-49	-	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S18
HKICGBDN_00895	5.67e-33	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HKICGBDN_00896	1.46e-118	-	-	-	T	-	-	-	Prokaryotic dksA/traR C4-type zinc finger
HKICGBDN_00897	6.89e-231	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKICGBDN_00898	2.86e-245	sun	2.1.1.176, 2.1.1.178	-	J	ko:K03500,ko:K11392	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKICGBDN_00899	1.79e-122	-	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HKICGBDN_00900	2.34e-97	nudI	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	GDP-mannose mannosyl hydrolase activity
HKICGBDN_00902	2.88e-283	-	-	-	M	ko:K02005	-	ko00000	HlyD family secretion protein
HKICGBDN_00903	2.12e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKICGBDN_00904	2.69e-310	-	-	-	V	-	-	-	MacB-like periplasmic core domain
HKICGBDN_00905	8.19e-316	-	-	-	MU	-	-	-	Outer membrane efflux protein
HKICGBDN_00906	1.57e-284	-	-	-	V	-	-	-	Beta-lactamase
HKICGBDN_00907	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKICGBDN_00908	6.02e-283	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKICGBDN_00909	1.02e-94	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HKICGBDN_00910	2.06e-166	-	-	-	S	-	-	-	Uncharacterised protein family UPF0066
HKICGBDN_00911	1.37e-306	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydro-orotase-like
HKICGBDN_00912	1.55e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
HKICGBDN_00913	1.15e-122	-	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Phosphoribosyl transferase domain
HKICGBDN_00914	3.73e-90	-	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	AIR carboxylase
HKICGBDN_00916	0.0	-	-	-	H	ko:K07137	-	ko00000	5-formyltetrahydrofolate cyclo-ligase activity
HKICGBDN_00917	6.45e-268	-	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Porphyromonas-type peptidyl-arginine deiminase
HKICGBDN_00918	2.11e-89	-	-	-	-	-	-	-	-
HKICGBDN_00919	0.0	rseP	3.4.21.116	-	M	ko:K06399,ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	metalloendopeptidase activity
HKICGBDN_00920	1.7e-297	-	-	-	S	-	-	-	AI-2E family transporter
HKICGBDN_00921	0.0	-	-	-	P	-	-	-	Domain of unknown function
HKICGBDN_00923	1.52e-81	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HKICGBDN_00924	1.93e-313	-	-	-	G	-	-	-	cellulose 1,4-beta-cellobiosidase activity
HKICGBDN_00925	4.02e-188	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKICGBDN_00927	1.83e-74	-	-	-	-	-	-	-	-
HKICGBDN_00928	0.0	-	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	DNA Topoisomerase IV
HKICGBDN_00930	1.63e-135	-	-	-	S	-	-	-	Glycosyl hydrolase 108
HKICGBDN_00933	1.24e-200	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
HKICGBDN_00934	5.07e-235	-	-	-	S	-	-	-	Peptidase family M28
HKICGBDN_00935	0.0	-	-	-	M	-	-	-	Aerotolerance regulator N-terminal
HKICGBDN_00936	0.0	-	-	-	S	-	-	-	Large extracellular alpha-helical protein
HKICGBDN_00939	1.11e-235	-	-	-	S	ko:K14347	-	ko00000,ko02000,ko04147	SBF-like CPA transporter family (DUF4137)
HKICGBDN_00940	2.64e-272	-	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	tRNA synthetases class I (W and Y)
HKICGBDN_00941	1.74e-85	-	-	-	S	ko:K09922	-	ko00000	Putative member of DMT superfamily (DUF486)
HKICGBDN_00942	4.4e-211	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HKICGBDN_00943	1.6e-217	-	-	-	EP	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKICGBDN_00944	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKICGBDN_00945	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HKICGBDN_00946	1.53e-219	-	-	-	O	-	-	-	Thioredoxin-like domain
HKICGBDN_00947	4.57e-311	-	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase C-terminal domain
HKICGBDN_00948	1.75e-235	-	-	-	S	ko:K01128	-	ko00000,ko01000	acid phosphatase activity
HKICGBDN_00952	0.0	-	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Tubulin/FtsZ family, GTPase domain
HKICGBDN_00953	3.38e-294	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKICGBDN_00954	1.72e-147	-	-	-	M	-	-	-	NLP P60 protein
HKICGBDN_00955	0.0	-	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
HKICGBDN_00956	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
HKICGBDN_00957	0.0	-	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter transmembrane region
HKICGBDN_00958	0.0	-	-	-	H	-	-	-	NAD synthase
HKICGBDN_00959	7.86e-174	-	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease MlaE
HKICGBDN_00960	4.3e-190	-	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKICGBDN_00961	1.33e-231	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MlaD protein
HKICGBDN_00962	2.69e-38	-	-	-	T	-	-	-	ribosome binding
HKICGBDN_00965	5.1e-265	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HKICGBDN_00966	9.11e-261	-	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	Type II/IV secretion system protein
HKICGBDN_00967	2.88e-249	ppiD	5.2.1.8	-	O	ko:K03769,ko:K03770,ko:K03771,ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl cis-trans isomerase activity
HKICGBDN_00969	0.0	-	-	-	-	-	-	-	-
HKICGBDN_00970	2.4e-180	kdsB	2.7.7.38	-	M	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HKICGBDN_00971	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKICGBDN_00972	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
HKICGBDN_00977	0.0	-	-	-	M	-	-	-	pathogenesis
HKICGBDN_00979	1.3e-265	-	-	GT4	M	ko:K16703	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HKICGBDN_00985	4.6e-149	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HKICGBDN_00988	2.94e-31	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HKICGBDN_00989	3.45e-31	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HKICGBDN_00990	4.74e-07	-	-	-	KLT	-	-	-	Lanthionine synthetase C-like protein
HKICGBDN_00991	8.51e-46	-	-	-	S	-	-	-	von Willebrand factor type A domain
HKICGBDN_00992	1.63e-121	-	-	-	S	-	-	-	Virulence protein RhuM family
HKICGBDN_00993	5.3e-07	RIPK1	2.7.11.1	-	T	ko:K02861	ko04064,ko04210,ko04217,ko04620,ko04621,ko04622,ko04623,ko04668,ko05160,ko05169,map04064,map04210,map04217,map04620,map04621,map04622,map04623,map04668,map05160,map05169	ko00000,ko00001,ko01000,ko01001	Receptor (TNFRSF)-interacting serine-threonine kinase 1
HKICGBDN_00997	9.42e-07	-	-	-	S	-	-	-	TM2 domain
HKICGBDN_01001	4.43e-39	-	-	-	-	-	-	-	-
HKICGBDN_01002	5.53e-96	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HKICGBDN_01003	3.15e-200	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HKICGBDN_01004	2.43e-101	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HKICGBDN_01005	9.77e-293	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HKICGBDN_01006	3.62e-108	-	-	-	S	-	-	-	Meiotically up-regulated gene 113
HKICGBDN_01007	1.19e-47	-	-	-	S	-	-	-	Domain of unknown function (DUF932)
HKICGBDN_01014	0.0	-	-	-	P	-	-	-	Cation transport protein
HKICGBDN_01015	2.48e-300	-	-	-	V	ko:K03327	-	ko00000,ko02000	drug transmembrane transporter activity
HKICGBDN_01016	1.83e-120	-	-	-	-	-	-	-	-
HKICGBDN_01017	9.86e-54	-	-	-	-	-	-	-	-
HKICGBDN_01018	7.2e-103	-	-	-	-	-	-	-	-
HKICGBDN_01019	0.0	-	2.1.1.182	-	IJ	ko:K02528	-	ko00000,ko01000,ko03009	Ribosomal RNA adenine dimethylases
HKICGBDN_01020	1.26e-247	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
HKICGBDN_01021	0.0	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
HKICGBDN_01022	0.0	-	-	-	I	-	-	-	Prenyltransferase and squalene oxidase repeat
HKICGBDN_01023	6.39e-119	-	-	-	T	-	-	-	STAS domain
HKICGBDN_01024	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF2851)
HKICGBDN_01025	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HKICGBDN_01026	3.09e-290	-	-	-	-	-	-	-	-
HKICGBDN_01027	0.0	-	-	-	M	-	-	-	Sulfatase
HKICGBDN_01028	6.68e-286	-	4.1.99.19	-	H	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Biotin and Thiamin Synthesis associated domain
HKICGBDN_01029	6.59e-205	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
HKICGBDN_01030	4.71e-267	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HKICGBDN_01031	0.0	-	-	-	T	-	-	-	pathogenesis
HKICGBDN_01032	0.0	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Dehydratase family
HKICGBDN_01033	6.89e-168	-	-	-	T	ko:K07657	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HKICGBDN_01034	5.8e-289	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HKICGBDN_01035	2.09e-10	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
HKICGBDN_01036	1.11e-206	hisG	2.4.2.17	-	E	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HKICGBDN_01037	2.04e-314	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
HKICGBDN_01038	5.68e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF3313)
HKICGBDN_01039	2.93e-260	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKICGBDN_01040	9.39e-256	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HKICGBDN_01041	2.8e-169	-	-	-	-	-	-	-	-
HKICGBDN_01042	0.0	-	-	-	NU	-	-	-	Type IV pilus assembly protein PilM;
HKICGBDN_01043	6.11e-208	-	-	-	-	-	-	-	-
HKICGBDN_01044	2.27e-245	-	-	-	-	-	-	-	-
HKICGBDN_01045	0.0	-	-	-	NU	ko:K02453	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Bacterial type II and III secretion system protein
HKICGBDN_01046	1.85e-142	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKICGBDN_01047	0.0	-	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKICGBDN_01048	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
HKICGBDN_01049	1.65e-240	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKICGBDN_01050	1.1e-131	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKICGBDN_01051	5.44e-229	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HKICGBDN_01052	0.0	-	1.11.1.5	-	P	ko:K00428	-	ko00000,ko01000	Di-haem cytochrome c peroxidase
HKICGBDN_01053	2.48e-40	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
HKICGBDN_01054	4.02e-48	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	iron ion homeostasis
HKICGBDN_01055	0.0	-	-	-	P	ko:K04759	-	ko00000,ko02000	Ferrous iron transport protein B C terminus
HKICGBDN_01058	2.83e-303	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
HKICGBDN_01060	0.0	-	-	-	P	-	-	-	E1-E2 ATPase
HKICGBDN_01061	4.92e-90	-	-	-	K	-	-	-	Helix-turn-helix diphteria tox regulatory element
HKICGBDN_01062	4.56e-206	-	3.1.1.53	-	L	ko:K03547,ko:K05970	-	ko00000,ko01000,ko03400	3'-5' exonuclease activity
HKICGBDN_01063	2.86e-133	-	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	SpoU rRNA Methylase family
HKICGBDN_01064	0.0	-	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
HKICGBDN_01065	9.76e-258	-	-	-	S	-	-	-	Glycoside-hydrolase family GH114
HKICGBDN_01066	8.72e-301	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKICGBDN_01068	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	RecQ zinc-binding
HKICGBDN_01069	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HKICGBDN_01070	8.66e-227	-	-	-	-	-	-	-	-
HKICGBDN_01071	1.97e-316	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HKICGBDN_01072	8.88e-247	-	-	-	-	-	-	-	-
HKICGBDN_01073	3.5e-249	rgpB	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HKICGBDN_01074	0.0	ahcY	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HKICGBDN_01075	3.77e-291	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKICGBDN_01076	3.9e-214	-	-	-	KQ	-	-	-	Hypothetical methyltransferase
HKICGBDN_01079	0.0	-	-	-	E	-	-	-	PFAM major facilitator superfamily MFS_1
HKICGBDN_01080	3.17e-206	-	-	-	G	ko:K06867,ko:K07001	-	ko00000	response to abiotic stimulus
HKICGBDN_01082	1.01e-293	-	-	-	MU	ko:K15725	-	ko00000,ko02000	efflux transmembrane transporter activity
HKICGBDN_01083	1.96e-297	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKICGBDN_01084	0.0	-	-	-	P	ko:K07239	-	ko00000	AcrB/AcrD/AcrF family
HKICGBDN_01085	3.44e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKICGBDN_01087	2.38e-169	-	-	-	CO	-	-	-	Protein conserved in bacteria
HKICGBDN_01088	2.6e-231	-	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HKICGBDN_01089	4.84e-155	-	1.14.11.27	-	P	ko:K10277	-	ko00000,ko01000,ko03036	peptidyl-arginine hydroxylation
HKICGBDN_01090	0.0	-	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Surface antigen
HKICGBDN_01091	8.38e-282	tig	-	-	O	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKICGBDN_01092	2.5e-153	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKICGBDN_01093	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKICGBDN_01094	3.39e-254	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKICGBDN_01096	9.94e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKICGBDN_01098	3.61e-46	-	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecE/Sec61-gamma subunits of protein translocation complex
HKICGBDN_01099	6.29e-135	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold.
HKICGBDN_01100	2.58e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKICGBDN_01101	1.74e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKICGBDN_01102	9.92e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKICGBDN_01103	3.69e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKICGBDN_01105	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKICGBDN_01107	1.02e-203	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HKICGBDN_01108	4.14e-175	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate reductase, N-terminus
HKICGBDN_01109	4.21e-121	-	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HKICGBDN_01110	4.13e-183	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HKICGBDN_01111	5.03e-229	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HKICGBDN_01112	7.29e-211	-	-	-	M	-	-	-	Peptidase family M23
HKICGBDN_01122	3.2e-21	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HKICGBDN_01125	7.5e-72	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HKICGBDN_01126	4.32e-06	Z012_11975	-	-	M	-	-	-	protein involved in exopolysaccharide biosynthesis
HKICGBDN_01127	4.52e-18	-	-	-	L	-	-	-	YqaJ-like viral recombinase domain
HKICGBDN_01135	1.6e-23	-	-	-	EH	-	-	-	sulfate reduction
HKICGBDN_01136	5.78e-63	-	-	-	L	-	-	-	D12 class N6 adenine-specific DNA methyltransferase
HKICGBDN_01139	6.3e-38	-	-	-	KL	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
HKICGBDN_01140	8.93e-141	-	-	-	K	ko:K12055	-	ko00000,ko02044	chromosome segregation
HKICGBDN_01144	2.29e-233	-	-	-	S	-	-	-	Phage terminase large subunit (GpA)
HKICGBDN_01146	1.12e-159	-	-	-	S	-	-	-	Phage portal protein, lambda family
HKICGBDN_01147	3.83e-96	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Clp protease
HKICGBDN_01148	2.69e-84	-	-	-	S	-	-	-	Phage major capsid protein E
HKICGBDN_01150	1.05e-16	-	-	-	-	-	-	-	-
HKICGBDN_01152	4.11e-203	-	-	-	S	ko:K06907	-	ko00000	COG3497 Phage tail sheath protein FI
HKICGBDN_01156	3.41e-58	-	-	-	D	-	-	-	phage tail tape measure protein
HKICGBDN_01157	4.95e-18	-	-	-	S	-	-	-	Phage Tail Protein X
HKICGBDN_01158	5.85e-62	-	-	-	S	ko:K06905	-	ko00000	COG3500 Phage protein D
HKICGBDN_01161	1.08e-12	-	-	-	-	-	-	-	-
HKICGBDN_01162	2.68e-56	-	-	-	S	-	-	-	Baseplate J-like protein
HKICGBDN_01163	5.77e-40	-	-	-	S	-	-	-	Phage tail protein (Tail_P2_I)
HKICGBDN_01164	1.5e-07	-	-	-	D	-	-	-	nuclear chromosome segregation
HKICGBDN_01168	8.59e-127	-	-	-	S	-	-	-	Glycosyl hydrolase 108
HKICGBDN_01169	6.51e-19	-	-	-	S	-	-	-	Phage Tail Collar Domain
HKICGBDN_01172	1.23e-110	-	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HKICGBDN_01173	1.26e-136	-	-	-	C	-	-	-	Nitroreductase family
HKICGBDN_01174	0.0	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
HKICGBDN_01175	1.66e-87	-	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HKICGBDN_01176	8.8e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKICGBDN_01177	8.07e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	tRNA (Guanine-1)-methyltransferase
HKICGBDN_01178	2.05e-28	-	-	-	-	-	-	-	-
HKICGBDN_01179	1.21e-238	-	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	RNA pseudouridylate synthase
HKICGBDN_01180	3.94e-243	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
HKICGBDN_01181	8.48e-56	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HKICGBDN_01182	0.0	-	-	-	J	ko:K07576	-	ko00000	Beta-Casp domain
HKICGBDN_01183	1.55e-83	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	ArsC family
HKICGBDN_01184	8.34e-180	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
HKICGBDN_01185	0.0	-	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Carbohydrate phosphorylase
HKICGBDN_01186	1.68e-257	tdh	1.1.1.103	-	E	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HKICGBDN_01187	2.31e-162	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKICGBDN_01189	1.62e-184	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HKICGBDN_01190	3.92e-115	-	-	-	-	-	-	-	-
HKICGBDN_01194	0.0	-	-	-	L	-	-	-	DNA restriction-modification system
HKICGBDN_01197	7.23e-164	-	-	-	S	-	-	-	PFAM Sel1 domain protein repeat-containing protein
HKICGBDN_01199	1.23e-177	-	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HKICGBDN_01201	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
HKICGBDN_01202	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKICGBDN_01203	2.76e-267	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKICGBDN_01204	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HKICGBDN_01206	0.0	-	-	-	G	-	-	-	alpha-galactosidase
HKICGBDN_01209	0.0	poxB	1.2.3.3, 1.2.5.1	-	EH	ko:K00156,ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Thiamine pyrophosphate enzyme, central domain
HKICGBDN_01210	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKICGBDN_01211	9.11e-182	-	-	-	L	ko:K10800	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	uracil-dna glycosylase
HKICGBDN_01212	1.13e-228	-	2.7.1.11	-	G	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Phosphofructokinase
HKICGBDN_01213	7.56e-271	-	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Male sterility protein
HKICGBDN_01214	9.14e-204	-	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKICGBDN_01216	0.0	-	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
HKICGBDN_01217	9.48e-192	-	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HKICGBDN_01218	0.0	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
HKICGBDN_01219	1.39e-54	-	-	-	I	-	-	-	PFAM biotin lipoyl attachment domain-containing protein
HKICGBDN_01221	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
HKICGBDN_01222	4.12e-100	-	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Glyoxalase-like domain
HKICGBDN_01223	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKICGBDN_01224	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKICGBDN_01226	0.000232	-	2.7.11.1, 2.7.11.17	-	T	ko:K08794,ko:K13412,ko:K17530	ko04626,ko04921,ko04925,ko05145,map04626,map04921,map04925,map05145	ko00000,ko00001,ko01000,ko01001	protein serine/threonine kinase activity
HKICGBDN_01227	0.0	-	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HKICGBDN_01228	1.34e-298	-	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKICGBDN_01229	3.13e-114	-	-	-	P	-	-	-	Rhodanese-like domain
HKICGBDN_01230	1.19e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HKICGBDN_01231	1.76e-186	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase (SPase) II
HKICGBDN_01232	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKICGBDN_01233	3.36e-247	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKICGBDN_01234	9.38e-260	-	-	-	S	-	-	-	Peptidase family M28
HKICGBDN_01235	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HKICGBDN_01236	5.62e-57	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HKICGBDN_01237	2.27e-90	-	-	-	S	ko:K09793	-	ko00000	Protein of unknown function (DUF456)
HKICGBDN_01238	2.45e-205	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HKICGBDN_01239	0.0	-	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	MacB-like periplasmic core domain
HKICGBDN_01240	3.74e-208	-	-	-	S	-	-	-	RDD family
HKICGBDN_01241	1.25e-132	-	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HKICGBDN_01242	1.4e-171	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HKICGBDN_01243	5.99e-286	-	-	-	S	ko:K09760	-	ko00000	RmuC family
HKICGBDN_01244	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Transglycosylase
HKICGBDN_01245	1.35e-240	-	-	-	O	-	-	-	Trypsin-like peptidase domain
HKICGBDN_01246	5.88e-277	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HKICGBDN_01248	7.91e-96	-	-	-	C	-	-	-	e3 binding domain
HKICGBDN_01249	3.93e-128	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HKICGBDN_01250	6.2e-265	-	-	-	S	-	-	-	PFAM glycosyl transferase family 2
HKICGBDN_01251	3.37e-292	-	-	-	-	-	-	-	-
HKICGBDN_01252	4.88e-263	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HKICGBDN_01253	3.06e-226	-	-	-	S	-	-	-	Glycosyl transferase family 11
HKICGBDN_01254	8.96e-274	-	-	GT2	S	ko:K19427	-	ko00000,ko01000	PFAM glycosyl transferase family 2
HKICGBDN_01256	1.24e-282	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HKICGBDN_01257	0.0	-	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Polyphosphate kinase middle domain
HKICGBDN_01258	0.0	-	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HKICGBDN_01259	8.13e-264	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HKICGBDN_01260	1.29e-192	map	3.4.11.18	-	J	ko:K01265	-	ko00000,ko01000,ko01002	Metallopeptidase family M24
HKICGBDN_01261	6.41e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKICGBDN_01262	0.0	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKICGBDN_01264	6.42e-101	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A
HKICGBDN_01265	3.38e-102	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKICGBDN_01266	2.38e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKICGBDN_01267	2.25e-105	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKICGBDN_01268	4.08e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKICGBDN_01269	5.36e-138	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKICGBDN_01270	1.53e-47	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal proteins 50S L24/mitochondrial 39S L24
HKICGBDN_01271	4.9e-207	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKICGBDN_01272	1.77e-124	-	-	-	M	ko:K03642	-	ko00000	Lytic transglycolase
HKICGBDN_01273	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HKICGBDN_01274	0.0	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 Helicase protein
HKICGBDN_01275	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKICGBDN_01277	1.53e-286	-	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
HKICGBDN_01278	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Collagenase
HKICGBDN_01280	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKICGBDN_01281	6.52e-75	-	-	-	L	-	-	-	Cupin 2, conserved barrel domain protein
HKICGBDN_01282	7.1e-130	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
HKICGBDN_01284	3.53e-295	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKICGBDN_01285	4.55e-213	-	-	-	K	-	-	-	LysR substrate binding domain
HKICGBDN_01286	3.36e-271	-	-	-	S	-	-	-	tRNA-splicing ligase RtcB
HKICGBDN_01287	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HKICGBDN_01289	2.51e-284	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKICGBDN_01291	2.57e-133	-	-	-	D	-	-	-	ErfK ybiS ycfS ynhG family protein
HKICGBDN_01292	0.0	-	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Aconitase C-terminal domain
HKICGBDN_01293	8.8e-169	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HKICGBDN_01297	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Bacterial DNA topoisomeraes I ATP-binding domain
HKICGBDN_01298	4.53e-100	-	-	-	-	-	-	-	-
HKICGBDN_01299	0.0	-	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase HemD
HKICGBDN_01300	2.24e-101	-	-	-	S	-	-	-	peptidase
HKICGBDN_01301	5.18e-172	-	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HKICGBDN_01302	2.1e-99	-	-	-	S	-	-	-	peptidase
HKICGBDN_01303	0.0	-	-	-	S	-	-	-	pathogenesis
HKICGBDN_01304	0.0	-	-	-	V	ko:K18095	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	AcrB/AcrD/AcrF family
HKICGBDN_01305	1e-242	-	-	-	M	ko:K18094	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01504,ko02000	Biotin-lipoyl like
HKICGBDN_01306	2.52e-197	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HKICGBDN_01307	1.13e-221	-	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HKICGBDN_01308	9.47e-236	-	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
HKICGBDN_01309	1.63e-298	-	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HKICGBDN_01310	4.72e-206	-	-	-	S	ko:K09949	-	ko00000	Protein of unknown function (DUF1009)
HKICGBDN_01313	4.67e-91	-	-	-	-	-	-	-	-
HKICGBDN_01314	2.28e-170	yyaQ	-	-	V	-	-	-	Protein conserved in bacteria
HKICGBDN_01315	5.06e-192	-	-	-	M	-	-	-	Glycosyl transferase WecB/TagA/CpsF family
HKICGBDN_01316	3.05e-189	-	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Metallo-beta-lactamase superfamily
HKICGBDN_01317	0.0	-	-	-	L	ko:K03631	-	ko00000,ko03400	RecF/RecN/SMC N terminal domain
HKICGBDN_01318	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HKICGBDN_01319	1.16e-244	-	-	-	G	-	-	-	Glycosyl hydrolases family 16
HKICGBDN_01320	9.29e-132	-	-	-	J	ko:K02356	-	ko00000,ko03012	Elongation factor P (EF-P) OB domain
HKICGBDN_01321	1.2e-105	-	-	-	S	-	-	-	ACT domain protein
HKICGBDN_01322	1.95e-312	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HKICGBDN_01323	3.06e-85	-	-	-	M	ko:K03282	-	ko00000,ko02000	Large-conductance mechanosensitive channel, MscL
HKICGBDN_01324	2.05e-277	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Alkaline phosphatase homologues
HKICGBDN_01325	4.06e-287	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKICGBDN_01326	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HKICGBDN_01327	8.88e-268	-	-	-	G	-	-	-	M42 glutamyl aminopeptidase
HKICGBDN_01329	1.96e-121	ngr	-	-	C	-	-	-	Rubrerythrin
HKICGBDN_01331	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1705)
HKICGBDN_01332	0.0	-	-	-	M	-	-	-	Glycosyl Hydrolase Family 88
HKICGBDN_01333	0.0	-	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
HKICGBDN_01334	3.8e-43	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	CTP reductase activity
HKICGBDN_01335	1.07e-188	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
HKICGBDN_01336	0.0	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
HKICGBDN_01337	0.0	-	-	-	T	-	-	-	Histidine kinase
HKICGBDN_01338	2.68e-110	-	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HKICGBDN_01339	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HKICGBDN_01340	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HKICGBDN_01341	7.36e-55	himA	-	-	L	ko:K03530,ko:K04764,ko:K05788	-	ko00000,ko03032,ko03036,ko03400	regulation of translation
HKICGBDN_01342	0.0	-	-	-	-	-	-	-	-
HKICGBDN_01345	3.31e-303	-	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	tRNA (Uracil-5-)-methyltransferase
HKICGBDN_01346	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HKICGBDN_01347	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
HKICGBDN_01348	3.29e-258	-	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKICGBDN_01349	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HKICGBDN_01350	1.47e-204	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKICGBDN_01351	1.73e-307	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKICGBDN_01352	0.0	-	-	-	-	-	-	-	-
HKICGBDN_01353	1.45e-162	-	-	-	S	-	-	-	SWIM zinc finger
HKICGBDN_01354	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase C-terminal
HKICGBDN_01355	0.0	-	-	-	U	ko:K03321	-	ko00000,ko02000	Sulfate permease family
HKICGBDN_01356	8.76e-126	-	-	-	-	-	-	-	-
HKICGBDN_01357	1.04e-109	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKICGBDN_01359	0.0	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HKICGBDN_01360	0.0	-	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	C-terminal, D2-small domain, of ClpB protein
HKICGBDN_01362	1.29e-230	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HKICGBDN_01364	1.05e-15	-	-	-	M	-	-	-	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HKICGBDN_01365	1.66e-33	-	-	-	S	-	-	-	conserved domain
HKICGBDN_01366	3.39e-92	-	-	-	L	-	-	-	IMG reference gene
HKICGBDN_01367	7.36e-56	-	-	-	S	-	-	-	PFAM Cupin 2 conserved barrel domain protein
HKICGBDN_01368	6.76e-131	-	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HKICGBDN_01369	0.0	-	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HKICGBDN_01370	0.0	-	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HKICGBDN_01372	2.4e-167	-	-	-	T	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HKICGBDN_01373	0.0	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
HKICGBDN_01375	2.66e-06	-	-	-	-	-	-	-	-
HKICGBDN_01376	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
HKICGBDN_01377	1.78e-266	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2219)
HKICGBDN_01378	4.37e-203	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HKICGBDN_01379	2.63e-84	-	-	-	M	-	-	-	Lysin motif
HKICGBDN_01380	3.05e-180	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKICGBDN_01381	0.0	-	-	-	V	-	-	-	MatE
HKICGBDN_01382	7.09e-251	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HKICGBDN_01384	1.02e-258	-	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKICGBDN_01386	9.86e-158	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
HKICGBDN_01387	9.16e-266	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	RibD C-terminal domain
HKICGBDN_01388	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKICGBDN_01389	4.27e-273	-	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
HKICGBDN_01390	0.0	-	-	-	O	-	-	-	Trypsin
HKICGBDN_01391	1.18e-109	-	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HKICGBDN_01392	0.0	-	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Oligonucleotide/oligosaccharide-binding (OB)-fold
HKICGBDN_01393	3.52e-161	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HKICGBDN_01394	0.0	-	-	-	P	-	-	-	Cation transport protein
HKICGBDN_01396	3.14e-179	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKICGBDN_01397	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
HKICGBDN_01398	3.2e-70	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HKICGBDN_01399	1.32e-101	manC	-	-	S	-	-	-	Cupin domain
HKICGBDN_01400	0.0	-	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HKICGBDN_01402	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class II (D, K and N)
HKICGBDN_01403	1.02e-187	pppL	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	protein serine/threonine phosphatase activity
HKICGBDN_01404	4.34e-152	-	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Glycerol-3-phosphate acyltransferase
HKICGBDN_01405	8.08e-236	gpsA	1.1.1.94	-	C	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HKICGBDN_01406	8.62e-102	-	-	-	-	-	-	-	-
HKICGBDN_01408	1.71e-264	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
HKICGBDN_01409	1.32e-313	pqqE	-	-	C	ko:K06139	-	ko00000	SMART Elongator protein 3 MiaB NifB
HKICGBDN_01410	0.0	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HKICGBDN_01411	4.94e-05	-	-	-	-	-	-	-	-
HKICGBDN_01412	0.0	-	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
HKICGBDN_01413	1.21e-210	-	-	-	S	-	-	-	Rhomboid family
HKICGBDN_01414	2.63e-269	-	-	-	E	-	-	-	FAD dependent oxidoreductase
HKICGBDN_01415	2.64e-267	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HKICGBDN_01418	0.0	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase
HKICGBDN_01419	3.45e-121	-	-	-	K	-	-	-	ParB domain protein nuclease
HKICGBDN_01422	9.25e-106	-	-	-	L	-	-	-	Staphylococcal nuclease homologues
HKICGBDN_01423	6.84e-248	-	-	-	M	-	-	-	Alginate lyase
HKICGBDN_01424	3.1e-207	-	-	-	IQ	-	-	-	KR domain
HKICGBDN_01427	7.17e-104	yciA	-	-	I	ko:K10806	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	acyl-coa hydrolase
HKICGBDN_01428	9.75e-316	hsrA	-	-	EGP	-	-	-	Major facilitator Superfamily
HKICGBDN_01429	1.41e-289	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HKICGBDN_01430	5.6e-241	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HKICGBDN_01431	4.57e-181	-	-	-	CH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HKICGBDN_01432	0.0	-	3.2.1.23	-	G	ko:K01190,ko:K12308	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
HKICGBDN_01433	8.77e-158	-	-	-	C	-	-	-	Nitroreductase family
HKICGBDN_01434	0.0	-	-	-	E	-	-	-	Transglutaminase-like
HKICGBDN_01435	5.58e-110	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
HKICGBDN_01436	6.56e-112	-	-	-	S	ko:K08999	-	ko00000	Bifunctional nuclease
HKICGBDN_01438	0.0	-	-	-	P	-	-	-	Citrate transporter
HKICGBDN_01441	2.8e-258	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
HKICGBDN_01442	0.0	-	-	-	I	-	-	-	Acyltransferase family
HKICGBDN_01443	2.57e-253	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
HKICGBDN_01444	5.02e-310	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKICGBDN_01445	1.03e-204	-	-	-	-	-	-	-	-
HKICGBDN_01446	2.74e-288	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKICGBDN_01447	2.26e-245	-	5.1.3.20	-	M	ko:K03274	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-beta hydroxysteroid dehydrogenase/isomerase family
HKICGBDN_01448	5.48e-235	-	-	GT9	M	ko:K02843,ko:K02849	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	ADP-heptose-lipopolysaccharide heptosyltransferase activity
HKICGBDN_01449	6.79e-249	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HKICGBDN_01450	9.15e-244	-	-	-	H	-	-	-	PFAM glycosyl transferase family 8
HKICGBDN_01451	1.03e-207	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HKICGBDN_01453	2.08e-241	-	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HKICGBDN_01454	9.36e-171	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKICGBDN_01455	5.8e-219	-	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin kinase
HKICGBDN_01456	9e-65	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HKICGBDN_01457	3.86e-76	-	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HKICGBDN_01458	3.3e-151	-	-	-	NU	-	-	-	Prokaryotic N-terminal methylation motif
HKICGBDN_01459	6.87e-256	-	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HKICGBDN_01460	3.17e-129	-	-	-	-	-	-	-	-
HKICGBDN_01461	1.02e-232	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HKICGBDN_01462	1.41e-30	-	-	-	S	-	-	-	NYN domain
HKICGBDN_01463	6.43e-153	ppaX_1	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	glycolate biosynthetic process
HKICGBDN_01464	6.45e-138	-	-	-	S	-	-	-	Maltose acetyltransferase
HKICGBDN_01465	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	GMP synthase C terminal domain
HKICGBDN_01466	0.0	-	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase / GMP reductase domain
HKICGBDN_01467	3.5e-121	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HKICGBDN_01468	0.0	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKICGBDN_01473	4.63e-77	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKICGBDN_01478	6.96e-64	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HKICGBDN_01479	2.33e-143	-	-	-	-	-	-	-	-
HKICGBDN_01481	0.0	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
HKICGBDN_01483	1.5e-180	-	-	-	-	-	-	-	-
HKICGBDN_01485	1.26e-112	-	-	-	CO	-	-	-	cell redox homeostasis
HKICGBDN_01486	6.11e-76	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HKICGBDN_01487	6.22e-74	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HKICGBDN_01488	1.3e-116	-	-	-	S	-	-	-	nitrogen fixation
HKICGBDN_01489	1.58e-148	dedA	-	-	S	-	-	-	FtsZ-dependent cytokinesis
HKICGBDN_01490	7.89e-268	-	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HKICGBDN_01491	0.0	-	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
HKICGBDN_01492	2.47e-253	-	-	-	L	-	-	-	Transposase IS200 like
HKICGBDN_01493	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HKICGBDN_01494	1.34e-109	ptsN	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02806	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HKICGBDN_01497	1.85e-149	-	-	-	-	-	-	-	-
HKICGBDN_01498	0.0	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HKICGBDN_01500	0.0	-	-	-	MU	ko:K18139	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Outer membrane efflux protein
HKICGBDN_01501	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKICGBDN_01502	1.58e-282	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKICGBDN_01503	0.0	prlC	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
HKICGBDN_01504	0.0	-	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	LeuA allosteric (dimerisation) domain
HKICGBDN_01506	6.78e-42	-	-	-	S	-	-	-	PurA ssDNA and RNA-binding protein
HKICGBDN_01507	1.23e-255	-	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Iron-sulfur cluster assembly protein
HKICGBDN_01508	0.0	-	-	-	V	ko:K03327	-	ko00000,ko02000	MatE
HKICGBDN_01511	0.0	-	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	HMGL-like
HKICGBDN_01512	0.0	-	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phospholipase D. Active site motifs.
HKICGBDN_01513	5.77e-208	-	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Thymidylate synthase
HKICGBDN_01514	8.33e-114	-	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Dihydrofolate reductase
HKICGBDN_01515	0.0	-	-	-	V	-	-	-	AcrB/AcrD/AcrF family
HKICGBDN_01516	4.2e-264	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Biotin-lipoyl like
HKICGBDN_01517	1.69e-107	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HKICGBDN_01519	8.82e-241	-	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase
HKICGBDN_01520	1.16e-158	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HKICGBDN_01521	1.48e-291	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
HKICGBDN_01522	1.71e-110	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HKICGBDN_01523	4.02e-121	-	-	-	-	-	-	-	-
HKICGBDN_01524	0.0	sepA	-	-	Q	-	-	-	COG2015, Alkyl sulfatase and related hydrolases
HKICGBDN_01525	1.82e-112	-	-	-	F	ko:K08311	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	NUDIX domain
HKICGBDN_01526	1.21e-241	-	-	-	E	ko:K07588	-	ko00000,ko01000	ArgK protein
HKICGBDN_01527	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HKICGBDN_01528	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HKICGBDN_01530	4.27e-117	gepA	-	-	K	-	-	-	Phage-associated protein
HKICGBDN_01531	1.15e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKICGBDN_01532	8.4e-136	thiE	2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17	-	H	ko:K00788,ko:K03147,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKICGBDN_01533	9.2e-215	-	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HKICGBDN_01534	8.64e-312	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HKICGBDN_01535	9.25e-103	-	-	-	K	-	-	-	Transcriptional regulator
HKICGBDN_01536	1.95e-273	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKICGBDN_01537	6.67e-172	-	-	-	P	ko:K10716	-	ko00000,ko02000	domain protein
HKICGBDN_01538	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Hsp90 protein
HKICGBDN_01539	0.0	-	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HKICGBDN_01540	1.11e-283	-	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
HKICGBDN_01541	6.99e-242	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Aminoacyl tRNA synthetase class II, N-terminal domain
HKICGBDN_01542	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	B3/4 domain
HKICGBDN_01543	1.75e-255	-	-	-	S	-	-	-	Domain of unknown function (DUF4105)
HKICGBDN_01544	6.76e-143	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
HKICGBDN_01545	0.0	-	4.1.99.1	-	E	ko:K01667	ko00380,map00380	ko00000,ko00001,ko01000	Beta-eliminating lyase
HKICGBDN_01546	2.01e-34	-	-	-	KLT	-	-	-	Tyrosine-protein kinase, subgroup, catalytic domain
HKICGBDN_01547	6.59e-227	-	-	-	S	-	-	-	Protein conserved in bacteria
HKICGBDN_01548	5.51e-211	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
HKICGBDN_01549	4.69e-159	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HKICGBDN_01550	8.93e-181	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Pyrroline-5-carboxylate reductase dimerisation
HKICGBDN_01553	2.75e-244	-	-	-	I	-	-	-	PFAM Prenyltransferase squalene oxidase
HKICGBDN_01554	2.94e-131	-	-	-	-	-	-	-	-
HKICGBDN_01555	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HKICGBDN_01556	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
HKICGBDN_01557	0.0	-	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Methylmalonyl-CoA mutase
HKICGBDN_01559	4.45e-225	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HKICGBDN_01560	3.86e-261	-	-	-	S	-	-	-	COG0790 FOG TPR repeat, SEL1 subfamily
HKICGBDN_01561	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglucose isomerase
HKICGBDN_01562	0.0	-	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Pyruvate phosphate dikinase, PEP/pyruvate binding domain
HKICGBDN_01563	4.25e-144	aat	2.3.2.6	-	O	ko:K00684	-	ko00000,ko01000	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HKICGBDN_01564	5.88e-259	-	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	endonuclease III
HKICGBDN_01565	2.18e-218	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKICGBDN_01566	0.0	-	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HKICGBDN_01568	2.72e-181	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
HKICGBDN_01569	1.12e-116	agmK	1.8.1.8	-	O	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	belongs to the thioredoxin family
HKICGBDN_01570	2.52e-281	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HKICGBDN_01571	0.0	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HKICGBDN_01573	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKICGBDN_01577	4.15e-129	-	-	-	S	-	-	-	Glycosyl hydrolase 108
HKICGBDN_01579	3.8e-80	-	-	-	S	-	-	-	Bacteriophage head to tail connecting protein
HKICGBDN_01583	6.03e-292	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HKICGBDN_01584	2.07e-195	-	-	-	KT	-	-	-	Peptidase S24-like
HKICGBDN_01586	2.66e-140	-	-	-	M	-	-	-	polygalacturonase activity
HKICGBDN_01587	1.39e-301	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HKICGBDN_01588	3.45e-239	-	1.2.7.3	-	-	ko:K00176,ko:K07138	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	-
HKICGBDN_01589	1.3e-205	-	-	-	S	-	-	-	Aldo/keto reductase family
HKICGBDN_01590	2.97e-268	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HKICGBDN_01591	4.24e-270	-	-	-	C	-	-	-	Aldo/keto reductase family
HKICGBDN_01592	8.47e-264	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HKICGBDN_01593	9.98e-129	-	-	-	C	-	-	-	FMN binding
HKICGBDN_01594	7.2e-103	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HKICGBDN_01595	1.11e-188	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
HKICGBDN_01596	4.8e-128	-	-	-	S	-	-	-	Flavodoxin-like fold
HKICGBDN_01597	7.97e-113	-	-	-	K	ko:K13640	-	ko00000,ko03000	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HKICGBDN_01598	1.65e-102	-	-	-	G	-	-	-	single-species biofilm formation
HKICGBDN_01599	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HKICGBDN_01600	0.0	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
HKICGBDN_01602	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HKICGBDN_01603	1.11e-239	-	4.2.1.113	-	M	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Mandelate Racemase Muconate Lactonizing
HKICGBDN_01604	3.06e-216	-	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HKICGBDN_01605	0.0	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	RNA cap guanine-N2 methyltransferase
HKICGBDN_01606	0.0	-	-	-	-	-	-	-	-
HKICGBDN_01607	4.7e-57	-	-	-	S	ko:K06960	-	ko00000	KH domain
HKICGBDN_01608	6.71e-285	-	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HKICGBDN_01609	2.45e-216	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKICGBDN_01612	2.05e-173	-	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	FtsJ-like methyltransferase
HKICGBDN_01614	1.84e-171	-	-	-	S	ko:K06911	-	ko00000	Pirin
HKICGBDN_01615	0.0	-	-	-	M	-	-	-	AsmA-like C-terminal region
HKICGBDN_01617	1.03e-201	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
HKICGBDN_01618	0.0	-	2.7.1.51	-	G	ko:K00879	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HKICGBDN_01620	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
HKICGBDN_01621	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HKICGBDN_01622	1.12e-121	-	-	-	-	-	-	-	-
HKICGBDN_01623	0.0	-	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	N-terminal domain of BNR-repeat neuraminidase
HKICGBDN_01624	2.06e-133	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
HKICGBDN_01625	7.29e-60	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
HKICGBDN_01626	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HKICGBDN_01627	0.0	-	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	ThiC-associated domain
HKICGBDN_01628	2.19e-220	ytpP	2.7.1.180, 5.3.4.1	-	CO	ko:K01829,ko:K03671,ko:K03734,ko:K06196	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko02000,ko03110	cell redox homeostasis
HKICGBDN_01629	1.3e-139	-	-	-	K	-	-	-	ECF sigma factor
HKICGBDN_01631	4.78e-222	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HKICGBDN_01632	3.06e-232	-	-	-	O	-	-	-	Parallel beta-helix repeats
HKICGBDN_01633	0.0	-	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
HKICGBDN_01634	1.95e-284	-	-	-	Q	-	-	-	Multicopper oxidase
HKICGBDN_01635	1.16e-209	-	-	-	EG	-	-	-	EamA-like transporter family
HKICGBDN_01637	2.2e-274	-	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKICGBDN_01638	6.48e-244	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HKICGBDN_01639	9.42e-232	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HKICGBDN_01640	0.0	-	-	-	E	ko:K13893	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKICGBDN_01641	0.0	-	-	-	P	ko:K13895	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKICGBDN_01642	0.0	-	-	-	EP	ko:K13894	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKICGBDN_01643	1.4e-185	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HKICGBDN_01644	1.35e-207	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKICGBDN_01645	9.98e-223	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase PanE/ApbA C terminal
HKICGBDN_01646	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate--tetrahydrofolate ligase
HKICGBDN_01647	5.77e-145	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
HKICGBDN_01648	8.95e-316	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
HKICGBDN_01649	3.77e-118	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
HKICGBDN_01650	2.52e-281	-	5.4.99.22	-	M	ko:K06178	-	ko00000,ko01000,ko03009	translation initiation factor activity
HKICGBDN_01651	1.27e-133	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HKICGBDN_01652	7.4e-93	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
HKICGBDN_01653	8.02e-130	-	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKICGBDN_01654	8.59e-293	-	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 57
HKICGBDN_01655	1.25e-315	-	-	-	G	-	-	-	Glycosyl transferase 4-like domain
HKICGBDN_01656	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 31
HKICGBDN_01657	6.05e-250	-	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	chorismate binding enzyme
HKICGBDN_01658	3.89e-313	-	-	-	C	ko:K00185	-	ko00000	Polysulphide reductase, NrfD
HKICGBDN_01660	7.47e-156	-	-	-	C	-	-	-	Cytochrome c
HKICGBDN_01661	4.3e-296	-	-	-	P	-	-	-	ABC-type Zn2 transport system, periplasmic component surface adhesin
HKICGBDN_01662	0.0	-	-	-	C	-	-	-	Cytochrome c
HKICGBDN_01664	1.38e-60	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKICGBDN_01665	1.13e-270	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HKICGBDN_01666	6.74e-307	-	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
HKICGBDN_01667	1.05e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF4230)
HKICGBDN_01668	2.48e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HKICGBDN_01669	8.67e-277	-	-	-	J	-	-	-	Beta-Casp domain
HKICGBDN_01670	4.02e-144	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKICGBDN_01671	1.02e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Queuosine biosynthesis protein QueC
HKICGBDN_01672	1.78e-97	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	QueF-like protein
HKICGBDN_01673	0.0	kefA	-	-	M	ko:K05802,ko:K22051	-	ko00000,ko02000	cellular water homeostasis
HKICGBDN_01674	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKICGBDN_01675	7.46e-238	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HKICGBDN_01676	1.44e-191	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin resistance protein BacA
HKICGBDN_01679	1.05e-84	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
HKICGBDN_01680	4.68e-315	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKICGBDN_01681	1.65e-303	-	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HKICGBDN_01682	1.33e-52	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKICGBDN_01683	4.17e-260	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKICGBDN_01685	8.29e-100	cysJ	1.8.1.2	-	C	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	hydroxylamine reductase activity
HKICGBDN_01687	5.74e-200	lpxG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HKICGBDN_01688	1.06e-169	BT0174	-	-	C	ko:K04488	-	ko00000	iron-sulfur transferase activity
HKICGBDN_01689	2.08e-240	BT0173	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKICGBDN_01691	7.78e-269	-	2.1.1.72	-	H	ko:K07318	-	ko00000,ko01000,ko02048	PFAM D12 class N6 adenine-specific DNA methyltransferase
HKICGBDN_01692	6.72e-210	-	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HKICGBDN_01697	3.48e-274	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HKICGBDN_01698	6.02e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKICGBDN_01699	2.49e-229	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HKICGBDN_01700	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
HKICGBDN_01701	4.66e-230	-	2.7.7.13	-	JM	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HKICGBDN_01702	4.47e-176	-	-	-	S	-	-	-	Phosphodiester glycosidase
HKICGBDN_01703	0.0	-	-	GT2	M	ko:K03820	-	ko00000,ko01000	Carbon-nitrogen hydrolase
HKICGBDN_01704	1.33e-51	-	-	-	C	-	-	-	4Fe-4S single cluster domain of Ferredoxin I
HKICGBDN_01705	1.12e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
HKICGBDN_01706	0.0	-	-	-	G	-	-	-	beta-N-acetylhexosaminidase activity
HKICGBDN_01707	2.52e-237	-	-	-	S	-	-	-	Acyltransferase family
HKICGBDN_01708	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
HKICGBDN_01709	2.69e-185	ccs1	-	-	O	ko:K07399	-	ko00000	cytochrome c biogenesis protein
HKICGBDN_01710	2.42e-209	fatB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion transport
HKICGBDN_01711	1.06e-180	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKICGBDN_01712	1.23e-228	fatC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
HKICGBDN_01713	4.39e-219	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	iron ion homeostasis
HKICGBDN_01714	2.43e-264	-	-	-	J	-	-	-	Endoribonuclease L-PSP
HKICGBDN_01715	0.0	-	-	-	C	-	-	-	Di-haem oxidoreductase, putative peroxidase
HKICGBDN_01716	7.56e-246	-	-	-	S	-	-	-	Imelysin
HKICGBDN_01717	6.48e-142	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HKICGBDN_01719	1.82e-125	-	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Phosphoribosyl transferase domain
HKICGBDN_01720	0.0	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	Helix-hairpin-helix class 2 (Pol1 family) motifs
HKICGBDN_01721	1.37e-249	-	-	-	M	-	-	-	HlyD family secretion protein
HKICGBDN_01722	1.78e-102	MA20_05485	-	-	S	-	-	-	Putative bacterial sensory transduction regulator
HKICGBDN_01723	0.0	-	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
HKICGBDN_01724	1.46e-302	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HKICGBDN_01725	0.0	-	-	-	D	-	-	-	Tetratricopeptide repeat
HKICGBDN_01726	1.47e-193	-	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HKICGBDN_01727	0.0	-	-	-	-	-	-	-	-
HKICGBDN_01728	6.55e-222	-	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
HKICGBDN_01729	6.68e-314	-	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HKICGBDN_01730	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
HKICGBDN_01731	5.32e-148	-	4.1.3.38	-	E	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	branched-chain-amino-acid transaminase activity
HKICGBDN_01732	1.04e-246	pabB	2.6.1.85, 4.1.3.27, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13503,ko:K13950	ko00400,ko00790,ko01100,ko01110,ko01130,ko01230,map00400,map00790,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKICGBDN_01733	2.09e-150	-	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HKICGBDN_01734	4.49e-269	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HKICGBDN_01735	2.5e-170	-	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
HKICGBDN_01736	2.11e-118	-	-	-	T	ko:K07005	-	ko00000	pyridoxamine 5'-phosphate
HKICGBDN_01737	7.17e-172	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Glutamine amidotransferase class-I
HKICGBDN_01739	2.87e-112	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Cys-tRNA(Pro) hydrolase activity
HKICGBDN_01740	0.0	mmyX	5.3.1.12	-	F	ko:K01812,ko:K07149,ko:K16139	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score
HKICGBDN_01741	6.74e-106	-	-	-	-	-	-	-	-
HKICGBDN_01744	4.37e-147	-	-	-	Q	-	-	-	PA14
HKICGBDN_01745	0.0	-	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	B12 binding domain
HKICGBDN_01746	1.66e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKICGBDN_01747	1.45e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HKICGBDN_01748	2.37e-312	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HKICGBDN_01749	1.1e-76	-	-	-	M	-	-	-	self proteolysis
HKICGBDN_01752	1.25e-87	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKICGBDN_01758	9.27e-75	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKICGBDN_01759	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HKICGBDN_01760	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HKICGBDN_01761	2.54e-132	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HKICGBDN_01763	1.11e-262	-	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Osmosensitive K+ channel His kinase sensor domain
HKICGBDN_01764	6.41e-236	-	2.7.11.1	-	T	ko:K08884,ko:K12132,ko:K20333	ko02024,map02024	ko00000,ko00001,ko01000,ko01001	PFAM Formylglycine-generating sulfatase enzyme
HKICGBDN_01766	7.19e-197	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HKICGBDN_01767	6e-142	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
HKICGBDN_01768	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HKICGBDN_01769	1.02e-282	-	-	-	C	-	-	-	Aldo/keto reductase family
HKICGBDN_01770	6.71e-90	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HKICGBDN_01771	2e-259	-	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HKICGBDN_01772	1.78e-293	-	-	-	-	-	-	-	-
HKICGBDN_01773	0.0	-	-	-	S	-	-	-	von Willebrand factor type A domain
HKICGBDN_01774	0.0	-	-	-	S	-	-	-	Aerotolerance regulator N-terminal
HKICGBDN_01775	4.72e-207	-	-	-	S	-	-	-	Protein of unknown function DUF58
HKICGBDN_01776	0.0	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
HKICGBDN_01777	1.78e-241	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HKICGBDN_01778	0.0	-	-	-	-	-	-	-	-
HKICGBDN_01779	1.49e-237	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HKICGBDN_01780	4.24e-296	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HKICGBDN_01782	9.45e-239	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HKICGBDN_01784	5.75e-202	-	-	-	O	-	-	-	stress-induced mitochondrial fusion
HKICGBDN_01785	2.34e-207	-	-	-	S	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
HKICGBDN_01786	8.5e-121	-	-	-	M	ko:K03098	-	ko00000,ko04147	Lipocalin-like domain
HKICGBDN_01787	1.35e-236	-	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKICGBDN_01788	7.18e-190	-	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKICGBDN_01789	8.26e-154	-	-	-	K	-	-	-	Transcriptional regulator
HKICGBDN_01792	0.0	-	-	-	P	-	-	-	Sulfatase
HKICGBDN_01793	1.04e-78	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
HKICGBDN_01794	4.6e-305	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKICGBDN_01795	0.0	-	-	-	E	-	-	-	Aminotransferase class I and II
HKICGBDN_01796	7.5e-221	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKICGBDN_01797	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Alpha galactosidase A
HKICGBDN_01798	1.04e-49	-	-	-	-	-	-	-	-
HKICGBDN_01799	1.45e-55	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HKICGBDN_01801	9.07e-234	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HKICGBDN_01802	2.13e-96	-	-	-	L	ko:K07447	-	ko00000,ko01000	Likely ribonuclease with RNase H fold.
HKICGBDN_01803	1.98e-258	-	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HKICGBDN_01804	1.06e-173	-	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKICGBDN_01805	0.0	-	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	TopoisomeraseII
HKICGBDN_01806	1.84e-206	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HKICGBDN_01808	0.0	-	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	HELICc2
HKICGBDN_01809	1.96e-178	cbiO	-	-	P	ko:K02006,ko:K02008,ko:K16784,ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase activity
HKICGBDN_01810	2.82e-194	cbiQ	-	-	P	ko:K02007,ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transmembrane transporter activity
HKICGBDN_01811	8.77e-239	cbiM	-	-	P	ko:K02007,ko:K02009,ko:K16915	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt ion transport
HKICGBDN_01813	5e-19	-	-	-	S	-	-	-	Lipocalin-like
HKICGBDN_01814	3.2e-209	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HKICGBDN_01815	1.81e-227	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKICGBDN_01816	1.06e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L9, N-terminal domain
HKICGBDN_01817	0.0	-	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT/IMPCHase bienzyme
HKICGBDN_01818	5.64e-173	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HKICGBDN_01819	9.05e-85	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	4'-phosphopantetheinyl transferase superfamily
HKICGBDN_01821	0.0	pckG	4.1.1.32	-	C	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle
HKICGBDN_01822	4.02e-166	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HKICGBDN_01823	0.0	-	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	RecG wedge domain
HKICGBDN_01825	0.0	-	-	-	C	ko:K00184	-	ko00000	4Fe-4S dicluster domain
HKICGBDN_01826	2.16e-180	-	-	-	C	-	-	-	Cytochrome c7 and related cytochrome c
HKICGBDN_01827	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKICGBDN_01829	1.9e-256	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Iron-containing alcohol dehydrogenase
HKICGBDN_01835	1.08e-266	-	-	-	H	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HKICGBDN_01836	0.0	yidC	-	-	O	ko:K03217,ko:K06872	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	serine-type endopeptidase activity
HKICGBDN_01837	3.06e-157	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKICGBDN_01838	2.76e-129	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKICGBDN_01839	1.02e-256	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
HKICGBDN_01840	4.86e-230	exsH	3.2.1.178, 3.2.1.18, 3.2.1.52	GH16,GH20,GH33	G	ko:K01186,ko:K12373,ko:K20830	ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko02042,ko03110	xyloglucan:xyloglucosyl transferase activity
HKICGBDN_01841	0.0	-	-	-	I	ko:K06889,ko:K09914	-	ko00000	PFAM Prenyltransferase squalene oxidase
HKICGBDN_01842	4.24e-314	-	1.1.1.40	-	C	ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,map00620,map00710,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Malic enzyme, NAD binding domain
HKICGBDN_01845	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HKICGBDN_01846	0.0	-	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
HKICGBDN_01847	2.14e-300	-	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HKICGBDN_01848	1.19e-92	-	5.1.3.29	-	G	ko:K02431	-	ko00000,ko01000	RbsD / FucU transport protein family
HKICGBDN_01849	6.17e-284	-	-	-	S	-	-	-	very-long-chain-acyl-CoA dehydrogenase activity
HKICGBDN_01851	0.0	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HKICGBDN_01852	3.82e-231	-	-	-	C	-	-	-	Nitroreductase family
HKICGBDN_01853	0.0	-	-	-	S	-	-	-	polysaccharide biosynthetic process
HKICGBDN_01854	3.13e-123	-	-	-	C	-	-	-	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKICGBDN_01855	1.58e-25	-	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
HKICGBDN_01856	6.17e-237	-	-	-	M	-	-	-	Glycosyl transferase, family 2
HKICGBDN_01857	3.34e-208	-	-	-	M	-	-	-	PFAM glycosyl transferase family 2
HKICGBDN_01858	2.67e-113	-	-	-	S	ko:K03818	-	ko00000,ko01000	maltose O-acetyltransferase activity
HKICGBDN_01859	0.0	-	-	-	-	-	-	-	-
HKICGBDN_01860	3.29e-279	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HKICGBDN_01861	5.24e-279	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HKICGBDN_01862	1.32e-249	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKICGBDN_01863	2.42e-198	-	-	-	S	-	-	-	Glycosyl transferase family 11
HKICGBDN_01864	9.16e-264	-	-	-	M	ko:K02847,ko:K13009	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	-O-antigen
HKICGBDN_01865	1.71e-241	-	-	-	-	-	-	-	-
HKICGBDN_01866	9.22e-290	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	transferase activity, transferring glycosyl groups
HKICGBDN_01867	8.15e-285	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HKICGBDN_01868	3.33e-289	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HKICGBDN_01869	1.77e-191	wbyL	-	GT2	M	ko:K13002	-	ko00000,ko01000,ko01003,ko01005	transferase activity, transferring glycosyl groups
HKICGBDN_01870	6.88e-176	-	-	-	M	-	-	-	Bacterial sugar transferase
HKICGBDN_01871	9.48e-165	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	protein tyrosine phosphatase activity
HKICGBDN_01872	0.0	gumC	-	-	DM	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	PFAM lipopolysaccharide biosynthesis protein
HKICGBDN_01873	5.68e-180	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	polysaccharide export
HKICGBDN_01874	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk_gamma
HKICGBDN_01876	7.6e-145	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKICGBDN_01877	1.08e-136	rbr	-	-	C	-	-	-	Rubrerythrin
HKICGBDN_01878	0.0	-	-	-	O	-	-	-	Cytochrome C assembly protein
HKICGBDN_01880	0.0	-	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Catalase
HKICGBDN_01881	1.01e-45	-	-	-	S	-	-	-	R3H domain
HKICGBDN_01883	0.0	-	1.2.1.88, 1.5.5.2	-	CE	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko03000	Proline dehydrogenase
HKICGBDN_01884	7.62e-284	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HKICGBDN_01885	3.05e-116	csd2	-	-	L	ko:K19118	-	ko00000,ko02048	CRISPR-associated protein, Csd2 family
HKICGBDN_01886	1.29e-133	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
HKICGBDN_01887	6.97e-107	-	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
HKICGBDN_01888	1.07e-83	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	DEAD-like helicases superfamily
HKICGBDN_01889	3.47e-59	cas4	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	crispr-associated protein cas4
HKICGBDN_01890	8.36e-119	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKICGBDN_01891	5.87e-32	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKICGBDN_01903	9.55e-242	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKICGBDN_01904	2.63e-208	-	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Polyprenyl synthetase
HKICGBDN_01905	1.19e-199	-	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
HKICGBDN_01906	3.45e-157	-	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
HKICGBDN_01907	2.45e-211	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HKICGBDN_01908	0.0	-	-	-	G	-	-	-	Trehalase
HKICGBDN_01909	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HKICGBDN_01910	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKICGBDN_01911	1.1e-34	-	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
HKICGBDN_01912	4.9e-76	-	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	Ribonuclease P
HKICGBDN_01913	1.09e-59	-	-	-	S	ko:K08998	-	ko00000	Haemolytic
HKICGBDN_01914	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
HKICGBDN_01915	0.0	-	1.4.1.13, 1.4.1.14	-	E	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
HKICGBDN_01916	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKICGBDN_01917	0.0	-	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HKICGBDN_01918	3.11e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase small chain, CPSase domain
HKICGBDN_01919	6.96e-265	-	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HKICGBDN_01920	1.31e-268	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
HKICGBDN_01921	8.01e-294	-	-	-	C	-	-	-	Na+/H+ antiporter family
HKICGBDN_01922	1.11e-236	-	-	-	-	-	-	-	-
HKICGBDN_01923	3.4e-229	-	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphomannose isomerase type I
HKICGBDN_01924	1.29e-181	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	PFAM N-acetylmuramoyl-L-alanine amidase family 2
HKICGBDN_01925	1.93e-117	ispF	4.6.1.12	-	I	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HKICGBDN_01926	6.64e-185	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HKICGBDN_01927	0.0	-	-	-	M	-	-	-	PFAM glycosyl transferase family 51
HKICGBDN_01928	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKICGBDN_01929	6.23e-97	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
HKICGBDN_01930	6.34e-183	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HKICGBDN_01931	0.0	-	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKICGBDN_01932	1.27e-99	-	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Predicted SPOUT methyltransferase
HKICGBDN_01933	1.67e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S9/S16
HKICGBDN_01934	2.79e-97	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKICGBDN_01935	6.12e-40	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKICGBDN_01936	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKICGBDN_01937	1.69e-174	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
HKICGBDN_01939	4.03e-174	-	-	-	D	-	-	-	Phage-related minor tail protein
HKICGBDN_01941	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKICGBDN_01942	8.25e-63	-	-	-	L	ko:K09747	-	ko00000	YbaB/EbfC DNA-binding family
HKICGBDN_01943	1.89e-253	-	-	-	N	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease Exonuclease Phosphatase
HKICGBDN_01944	0.0	-	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	DHHA2
HKICGBDN_01946	5.46e-189	-	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
HKICGBDN_01947	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
HKICGBDN_01948	0.000651	-	-	-	-	-	-	-	-
HKICGBDN_01949	0.0	-	-	-	G	-	-	-	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain
HKICGBDN_01952	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Prolyl-tRNA synthetase, C-terminal
HKICGBDN_01953	2.04e-158	-	-	-	S	-	-	-	Peptidase family M50
HKICGBDN_01955	2.27e-215	-	-	-	JM	-	-	-	Nucleotidyl transferase
HKICGBDN_01956	8.25e-273	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HKICGBDN_01957	1.01e-222	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NmrA-like family
HKICGBDN_01959	0.0	-	-	-	L	ko:K07478	-	ko00000	MgsA AAA+ ATPase C terminal
HKICGBDN_01960	5.87e-296	-	-	-	-	-	-	-	-
HKICGBDN_01961	0.0	-	-	-	-	-	-	-	-
HKICGBDN_01962	1.03e-138	mntP	-	-	P	-	-	-	manganese ion transmembrane transporter activity
HKICGBDN_01964	4.17e-190	-	-	-	S	-	-	-	Phenazine biosynthesis-like protein
HKICGBDN_01965	9.46e-176	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKICGBDN_01966	0.0	-	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, Activator interacting domain (AID)
HKICGBDN_01967	5.48e-273	ycaD	-	-	EGP	ko:K08219	-	ko00000,ko02000	Major facilitator Superfamily
HKICGBDN_01968	4.27e-225	-	3.4.11.10, 3.4.11.6	-	DZ	ko:K19701	-	ko00000,ko01000,ko01002	aminopeptidase activity
HKICGBDN_01969	1.16e-287	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HKICGBDN_01970	0.0	-	-	-	S	-	-	-	inositol 2-dehydrogenase activity
HKICGBDN_01972	6.73e-286	-	3.6.4.13	-	L	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	helicase superfamily c-terminal domain
HKICGBDN_01974	3.6e-145	-	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	CDP-alcohol phosphatidyltransferase
HKICGBDN_01975	0.0	-	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKICGBDN_01976	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HKICGBDN_01977	9.77e-278	-	4.2.1.51, 5.4.99.5	-	E	ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
HKICGBDN_01978	3.72e-237	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKICGBDN_01979	1.91e-191	-	-	-	S	-	-	-	NIF3 (NGG1p interacting factor 3)
HKICGBDN_01980	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
HKICGBDN_01981	0.0	-	-	-	N	-	-	-	ABC-type uncharacterized transport system
HKICGBDN_01982	1.01e-182	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKICGBDN_01983	1.09e-223	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKICGBDN_01984	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKICGBDN_01985	2.38e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	nUDIX hydrolase
HKICGBDN_01987	1.52e-40	xerD1	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HKICGBDN_01988	2.16e-21	traC	-	-	P	-	-	-	DNA integration
HKICGBDN_01989	1.49e-06	-	-	-	L	ko:K07505	-	ko00000	Primase C terminal 2 (PriCT-2)
HKICGBDN_01990	7.09e-65	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
HKICGBDN_01992	1.43e-09	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HKICGBDN_01993	1.01e-23	-	-	-	-	-	-	-	-
HKICGBDN_02001	2.74e-06	-	-	-	-	-	-	-	-
HKICGBDN_02003	1.07e-10	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HKICGBDN_02004	2.35e-28	-	-	-	S	-	-	-	chitin catabolic process
HKICGBDN_02021	9.17e-70	-	-	-	M	-	-	-	Polymer-forming cytoskeletal
HKICGBDN_02022	2.53e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKICGBDN_02023	4.62e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Amino acid kinase family
HKICGBDN_02024	1.45e-208	-	-	-	M	-	-	-	Mechanosensitive ion channel
HKICGBDN_02025	3.6e-152	-	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HKICGBDN_02026	0.0	-	-	-	S	-	-	-	Sodium:neurotransmitter symporter family
HKICGBDN_02027	0.0	-	-	-	-	-	-	-	-
HKICGBDN_02028	2.37e-46	-	-	-	J	-	-	-	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKICGBDN_02029	5.12e-145	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKICGBDN_02031	3.9e-306	-	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKICGBDN_02032	1.98e-109	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07305,ko:K12267	-	ko00000,ko01000	peptide-methionine (R)-S-oxide reductase activity
HKICGBDN_02033	4.16e-259	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKICGBDN_02034	4.4e-112	nupG	-	-	G	ko:K03289,ko:K03301,ko:K08218,ko:K11537	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HKICGBDN_02035	2.94e-162	nupG	-	-	G	ko:K03289,ko:K03301,ko:K08218,ko:K11537	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HKICGBDN_02042	7.57e-247	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKICGBDN_02043	1.03e-243	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKICGBDN_02044	0.0	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKICGBDN_02045	1.37e-227	-	-	-	M	ko:K01993	-	ko00000	HlyD family secretion protein
HKICGBDN_02046	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKICGBDN_02047	3.85e-194	-	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	CDP-alcohol phosphatidyltransferase
HKICGBDN_02048	4.03e-120	-	-	-	-	-	-	-	-
HKICGBDN_02049	1.51e-198	-	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HKICGBDN_02050	0.0	-	-	-	M	-	-	-	Bacterial membrane protein, YfhO
HKICGBDN_02051	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GcpE protein
HKICGBDN_02052	5.44e-147	-	-	-	IQ	-	-	-	RmlD substrate binding domain
HKICGBDN_02053	3.91e-289	-	-	-	S	-	-	-	Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units
HKICGBDN_02054	0.0	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	thiolester hydrolase activity
HKICGBDN_02055	2.33e-281	-	-	-	IQ	-	-	-	Beta-ketoacyl synthase, C-terminal domain
HKICGBDN_02056	6.65e-261	-	2.3.1.47	-	H	ko:K00652	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HKICGBDN_02060	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HKICGBDN_02061	7.37e-311	-	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
HKICGBDN_02062	1.44e-175	hypB	-	-	KO	ko:K04652	-	ko00000,ko03110	CobW/HypB/UreG, nucleotide-binding domain
HKICGBDN_02063	0.0	-	-	-	O	ko:K04656	-	ko00000	HypF finger
HKICGBDN_02064	2.74e-50	-	-	-	O	ko:K04653	-	ko00000	HupF/HypC family
HKICGBDN_02065	1.11e-261	-	-	-	O	ko:K04654	-	ko00000	Hydrogenase formation hypA family
HKICGBDN_02066	5.1e-241	-	-	-	O	ko:K04655	-	ko00000	AIR synthase related protein, N-terminal domain
HKICGBDN_02068	6.21e-39	-	-	-	-	-	-	-	-
HKICGBDN_02069	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKICGBDN_02071	9.83e-235	-	-	-	CO	-	-	-	Thioredoxin-like
HKICGBDN_02072	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HKICGBDN_02073	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HKICGBDN_02074	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	tRNA synthetases class I (C) catalytic domain
HKICGBDN_02075	1.6e-75	-	-	-	G	-	-	-	Cupin 2, conserved barrel domain protein
HKICGBDN_02076	3.32e-210	ybfH	-	-	EG	-	-	-	spore germination
HKICGBDN_02077	6.7e-132	-	-	-	-	-	-	-	-
HKICGBDN_02078	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HKICGBDN_02079	1.47e-120	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKICGBDN_02080	7.48e-188	-	-	-	O	ko:K04083	-	ko00000,ko03110	Hsp33 protein
HKICGBDN_02083	2.93e-233	-	-	-	E	-	-	-	PFAM lipolytic protein G-D-S-L family
HKICGBDN_02087	1.39e-128	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
HKICGBDN_02088	5.94e-178	-	4.2.99.20	-	I	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
HKICGBDN_02089	1.46e-75	-	-	-	S	ko:K09954	-	ko00000	Putative quorum-sensing-regulated virulence factor
HKICGBDN_02091	1.24e-51	-	-	-	-	-	-	-	-
HKICGBDN_02092	8.46e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
HKICGBDN_02093	1.96e-184	-	-	-	-	-	-	-	-
HKICGBDN_02094	2.59e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF2589)
HKICGBDN_02095	1.88e-111	-	-	-	KT	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
HKICGBDN_02096	1.17e-304	-	-	-	C	-	-	-	4 iron, 4 sulfur cluster binding
HKICGBDN_02097	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HKICGBDN_02098	1.05e-219	-	-	-	K	-	-	-	Transcriptional regulator
HKICGBDN_02099	6.03e-178	-	-	-	C	-	-	-	aldo keto reductase
HKICGBDN_02100	8.36e-186	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HKICGBDN_02101	2.9e-275	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HKICGBDN_02102	2.77e-308	-	-	-	C	-	-	-	Carboxymuconolactone decarboxylase family
HKICGBDN_02103	2.29e-157	-	-	-	IQ	-	-	-	Short chain dehydrogenase
HKICGBDN_02104	1.55e-24	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HKICGBDN_02106	4.21e-137	-	-	-	J	ko:K05808	-	ko00000,ko03009	Sigma 54 modulation/S30EA ribosomal protein C terminus
HKICGBDN_02108	2.98e-08	-	-	-	M	-	-	-	major outer membrane lipoprotein
HKICGBDN_02109	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HKICGBDN_02111	2.07e-169	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HKICGBDN_02112	7.5e-306	-	-	-	C	-	-	-	Sulfatase-modifying factor enzyme 1
HKICGBDN_02113	1.43e-11	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKICGBDN_02115	0.000576	-	-	-	-	-	-	-	-
HKICGBDN_02117	7.45e-49	XK27_09985	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HKICGBDN_02118	1.43e-194	-	-	-	S	ko:K07051	-	ko00000	TatD related DNase
HKICGBDN_02119	8.94e-56	-	-	-	-	-	-	-	-
HKICGBDN_02120	4.83e-163	-	-	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	-
HKICGBDN_02121	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Fumarate reductase flavoprotein C-term
HKICGBDN_02122	1.29e-187	-	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	2Fe-2S iron-sulfur cluster binding domain
HKICGBDN_02124	4.43e-291	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HKICGBDN_02125	1.28e-276	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal
HKICGBDN_02126	1.79e-122	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKICGBDN_02127	3.09e-61	-	-	-	J	-	-	-	RF-1 domain
HKICGBDN_02128	1.67e-123	-	-	-	-	-	-	-	-
HKICGBDN_02129	0.0	-	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP--glucose-1-phosphate uridylyltransferase
HKICGBDN_02130	1.84e-183	-	2.1.1.144, 2.1.1.197	-	FG	ko:K00598,ko:K02169	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	trans-aconitate 2-methyltransferase activity
HKICGBDN_02132	1.69e-127	-	-	-	S	-	-	-	protein trimerization
HKICGBDN_02133	2.72e-36	-	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HKICGBDN_02134	2.88e-63	tagD	2.7.7.39	-	H	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HKICGBDN_02135	1.45e-29	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	PFAM glycosyltransferase sugar-binding region containing DXD motif
HKICGBDN_02136	1.14e-229	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
HKICGBDN_02137	0.0	-	2.7.7.15	-	H	ko:K00968	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HKICGBDN_02138	1.5e-95	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
HKICGBDN_02139	0.0	cobD	2.6.1.9, 2.7.7.74, 4.1.1.81	-	M	ko:K00817,ko:K04720,ko:K07281	ko00340,ko00350,ko00360,ko00400,ko00401,ko00562,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00562,map00860,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	nucleotidyl transferase
HKICGBDN_02140	4.15e-262	-	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
HKICGBDN_02141	0.0	-	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha amylase, C-terminal all-beta domain
HKICGBDN_02143	1.45e-93	-	-	-	S	ko:K02426	-	ko00000	Fe-S metabolism associated domain
HKICGBDN_02144	1.64e-223	-	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKICGBDN_02145	0.0	-	-	-	P	-	-	-	Sulfatase
HKICGBDN_02146	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKICGBDN_02147	8.72e-53	-	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
HKICGBDN_02148	3.12e-223	hprK	-	-	T	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
HKICGBDN_02149	0.0	-	-	-	E	-	-	-	Peptidase dimerisation domain
HKICGBDN_02150	8.83e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKICGBDN_02151	1.36e-137	-	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
HKICGBDN_02152	0.0	-	-	-	S	-	-	-	50S ribosome-binding GTPase
HKICGBDN_02153	4.14e-163	-	-	-	S	ko:K06997	-	ko00000	Alanine racemase, N-terminal domain
HKICGBDN_02154	1.88e-135	-	-	-	K	ko:K07735	-	ko00000,ko03000	Uncharacterized ACR, COG1678
HKICGBDN_02155	6.07e-192	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKICGBDN_02156	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HKICGBDN_02157	7.47e-203	-	-	-	-	-	-	-	-
HKICGBDN_02158	8.46e-84	-	-	-	P	ko:K06195	-	ko00000	ApaG domain
HKICGBDN_02159	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HKICGBDN_02160	8.26e-106	-	-	-	K	-	-	-	Lrp/AsnC ligand binding domain
HKICGBDN_02161	1.59e-286	-	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
HKICGBDN_02162	1.93e-209	-	-	-	S	-	-	-	CAAX protease self-immunity
HKICGBDN_02163	3.7e-156	-	-	-	S	-	-	-	DUF218 domain
HKICGBDN_02164	0.0	-	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Anticodon binding domain
HKICGBDN_02165	1.16e-205	yeaE	-	-	S	-	-	-	aldo-keto reductase (NADP) activity
HKICGBDN_02166	0.0	-	-	-	S	-	-	-	Oxygen tolerance
HKICGBDN_02167	8.51e-42	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HKICGBDN_02169	2.3e-229	-	-	-	S	-	-	-	Protein of unknown function (DUF1194)
HKICGBDN_02170	8.06e-134	-	-	-	-	-	-	-	-
HKICGBDN_02171	1.26e-210	-	-	-	S	-	-	-	Protein of unknown function DUF58
HKICGBDN_02172	2.48e-228	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HKICGBDN_02173	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKICGBDN_02174	8.23e-62	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKICGBDN_02176	2.63e-10	-	-	-	-	-	-	-	-
HKICGBDN_02179	2.74e-284	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKICGBDN_02180	0.0	-	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
HKICGBDN_02181	6.2e-203	-	-	-	-	-	-	-	-
HKICGBDN_02182	3.31e-239	-	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HKICGBDN_02183	3.4e-178	-	-	-	O	-	-	-	Trypsin
HKICGBDN_02189	4.71e-33	-	-	-	M	-	-	-	lytic transglycosylase activity
HKICGBDN_02190	4.93e-64	-	-	-	F	-	-	-	acetyltransferase
HKICGBDN_02192	1.04e-65	-	-	-	KT	-	-	-	Peptidase S24-like
HKICGBDN_02204	1.54e-305	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	DnaB-like helicase C terminal domain
HKICGBDN_02210	5.03e-28	-	-	-	-	-	-	-	-
HKICGBDN_02212	4.25e-160	-	-	-	S	-	-	-	Terminase
HKICGBDN_02213	4.65e-16	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKICGBDN_02216	1.38e-205	-	-	-	M	-	-	-	self proteolysis
HKICGBDN_02217	7.66e-106	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKICGBDN_02219	2.93e-39	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKICGBDN_02220	1.07e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKICGBDN_02221	5.19e-178	-	-	-	S	-	-	-	Lysin motif
HKICGBDN_02222	3.5e-132	-	-	-	-	-	-	-	-
HKICGBDN_02223	8.56e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
HKICGBDN_02224	7.16e-174	coaX	2.7.1.33	-	K	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Type III pantothenate kinase
HKICGBDN_02225	6.81e-273	-	-	-	M	-	-	-	Monogalactosyldiacylglycerol (MGDG) synthase
HKICGBDN_02226	3.02e-227	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKICGBDN_02227	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	UvrD-like helicase C-terminal domain
HKICGBDN_02229	0.0	-	-	-	S	ko:K03307	-	ko00000	Sodium:solute symporter family
HKICGBDN_02230	8.88e-284	-	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Galactokinase galactose-binding signature
HKICGBDN_02231	0.0	-	-	-	M	-	-	-	Bacterial sugar transferase
HKICGBDN_02232	7.33e-143	-	-	-	S	-	-	-	RNA recognition motif
HKICGBDN_02233	1.02e-184	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKICGBDN_02234	0.0	-	-	-	-	-	-	-	-
HKICGBDN_02236	0.0	-	-	-	V	-	-	-	ABC-2 type transporter
HKICGBDN_02237	0.0	-	-	-	C	-	-	-	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein
HKICGBDN_02238	2.83e-204	-	-	-	S	-	-	-	Domain of unknown function (DUF362)
HKICGBDN_02239	2.47e-134	-	-	-	J	-	-	-	Putative rRNA methylase
HKICGBDN_02240	1.72e-144	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKICGBDN_02241	3.73e-195	-	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
HKICGBDN_02242	5.58e-289	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	NusA-like KH domain
HKICGBDN_02243	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKICGBDN_02244	3.87e-80	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKICGBDN_02245	0.0	-	-	-	P	-	-	-	PA14 domain
HKICGBDN_02246	9.44e-159	-	-	-	-	-	-	-	-
HKICGBDN_02247	0.0	-	-	-	T	-	-	-	5TM C-terminal transporter carbon starvation CstA
HKICGBDN_02248	0.0	-	-	-	EGIP	-	-	-	Phosphate acyltransferases
HKICGBDN_02249	4.05e-135	-	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKICGBDN_02250	4.34e-284	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKICGBDN_02251	3.53e-255	-	-	-	S	-	-	-	Putative S-adenosyl-L-methionine-dependent methyltransferase
HKICGBDN_02252	1.38e-226	-	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate synthetase A protein
HKICGBDN_02253	1.26e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKICGBDN_02254	0.0	-	3.2.1.52	GH20	G	ko:K01207,ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko01501,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map01501,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycoside hydrolase, family 20, catalytic core
HKICGBDN_02256	5.32e-108	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HKICGBDN_02258	0.0	-	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HKICGBDN_02259	2.57e-251	-	-	-	S	ko:K11941	-	ko00000,ko01000	transferase activity, transferring acyl groups other than amino-acyl groups
HKICGBDN_02260	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HKICGBDN_02264	5.93e-261	-	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HKICGBDN_02265	8.43e-155	-	1.5.1.34	-	C	ko:K10679	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HKICGBDN_02266	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, domain 2
HKICGBDN_02267	1.76e-179	-	-	-	M	-	-	-	NLP P60 protein
HKICGBDN_02268	6.77e-87	-	-	-	S	ko:K09940	-	ko00000	Domain of unknown function (DUF4870)
HKICGBDN_02270	4.94e-75	-	-	-	C	ko:K04651	-	ko00000,ko03110	Hydrogenase/urease nickel incorporation, metallochaperone, hypA
HKICGBDN_02271	3.4e-126	-	-	-	C	ko:K03605	-	ko00000,ko01000,ko01002	Hydrogenase maturation protease
HKICGBDN_02272	6.49e-290	hyaC	-	-	C	ko:K03620	ko02020,map02020	ko00000,ko00001	Prokaryotic cytochrome b561
HKICGBDN_02273	0.0	-	1.12.99.6	-	C	ko:K06281	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	Nickel-dependent hydrogenase
HKICGBDN_02274	6.94e-298	-	1.12.99.6	-	C	ko:K06282	ko00633,ko01120,map00633,map01120	ko00000,ko00001,ko01000	NiFe/NiFeSe hydrogenase small subunit C-terminal
HKICGBDN_02275	0.0	-	-	-	M	ko:K07267	-	ko00000,ko02000	wide pore channel activity
HKICGBDN_02277	9.83e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKICGBDN_02278	0.0	-	-	-	H	-	-	-	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKICGBDN_02279	0.0	-	3.4.24.3	-	NU	ko:K01387	-	ko00000,ko01000,ko01002,ko02042	translation initiation factor activity
HKICGBDN_02280	0.0	-	-	-	M	-	-	-	Transglycosylase
HKICGBDN_02281	2.63e-135	-	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	Peptidyl-tRNA hydrolase
HKICGBDN_02282	4.58e-215	-	-	-	S	-	-	-	Protein of unknown function DUF58
HKICGBDN_02283	3.82e-231	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HKICGBDN_02284	2.46e-216	-	3.5.1.53	-	K	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HKICGBDN_02286	2.36e-273	-	-	-	E	-	-	-	Alcohol dehydrogenase GroES-like domain
HKICGBDN_02287	2.56e-309	-	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Seryl-tRNA synthetase N-terminal domain
HKICGBDN_02289	0.0	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HKICGBDN_02290	0.0	-	3.4.24.70	-	E	ko:K01414	-	ko00000,ko01000,ko01002	Peptidase family M3
HKICGBDN_02292	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
HKICGBDN_02294	1.87e-215	-	-	-	K	-	-	-	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HKICGBDN_02295	1.73e-123	paiA	-	-	K	-	-	-	acetyltransferase
HKICGBDN_02296	5.44e-232	-	-	-	CO	-	-	-	Redoxin
HKICGBDN_02297	1.12e-83	-	-	-	K	ko:K07343	-	ko00000	positive regulation of type IV pilus biogenesis
HKICGBDN_02298	2.11e-173	-	6.3.5.11, 6.3.5.9	-	V	ko:K02224,ko:K18554	ko00860,ko01100,ko01120,map00860,map01100,map01120	br01600,ko00000,ko00001,ko01000,ko01504	Chloramphenicol phosphotransferase-like protein
HKICGBDN_02300	0.0	-	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKICGBDN_02301	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKICGBDN_02302	5e-252	-	2.3.1.1	-	E	ko:K14682	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
HKICGBDN_02304	2.05e-42	-	-	-	S	-	-	-	Phage terminase large subunit (GpA)
HKICGBDN_02307	1.05e-19	-	-	-	OU	-	-	-	Belongs to the peptidase S14 family
HKICGBDN_02321	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKICGBDN_02322	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA Topoisomerase IV
HKICGBDN_02323	2.66e-147	-	-	-	C	-	-	-	lactate oxidation
HKICGBDN_02324	1.02e-296	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32
HKICGBDN_02325	1e-20	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	COG0010 Arginase agmatinase formimionoglutamate hydrolase arginase family
HKICGBDN_02326	0.0	-	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HKICGBDN_02327	0.0	-	-	-	C	-	-	-	cytochrome C peroxidase
HKICGBDN_02328	6.9e-282	-	-	-	J	-	-	-	PFAM Endoribonuclease L-PSP
HKICGBDN_02330	1.33e-151	phoU	-	-	P	ko:K02039	-	ko00000	negative regulation of phosphate transmembrane transport
HKICGBDN_02331	8.04e-184	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKICGBDN_02332	0.0	-	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKICGBDN_02333	0.0	pstC	-	-	P	ko:K02037,ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKICGBDN_02334	1.51e-221	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	PBP superfamily domain
HKICGBDN_02335	5.24e-185	-	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKICGBDN_02336	5.19e-140	-	-	-	P	ko:K02039	-	ko00000	PhoU domain
HKICGBDN_02337	6.15e-234	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HKICGBDN_02338	7.65e-101	-	-	-	M	ko:K06077	-	ko00000	Glycine zipper 2TM domain
HKICGBDN_02340	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Insulinase (Peptidase family M16)
HKICGBDN_02341	4.72e-153	-	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HKICGBDN_02342	2.13e-230	-	-	-	L	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HKICGBDN_02343	3.03e-231	-	-	-	J	-	-	-	Belongs to the universal ribosomal protein uS2 family
HKICGBDN_02344	2.51e-103	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HKICGBDN_02353	3.01e-188	-	5.2.1.8	-	O	ko:K03773	-	ko00000,ko01000,ko03110	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
HKICGBDN_02354	4.4e-138	-	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKICGBDN_02355	2.46e-272	-	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
HKICGBDN_02356	2.09e-207	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HKICGBDN_02357	0.0	-	-	-	P	ko:K03455	-	ko00000	TrkA-N domain
HKICGBDN_02358	1.2e-167	-	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HKICGBDN_02364	1.14e-134	panZ	-	-	K	-	-	-	-acetyltransferase
HKICGBDN_02365	2.11e-219	-	-	-	E	ko:K00612	-	ko00000,ko01000	lipolytic protein G-D-S-L family
HKICGBDN_02366	7.15e-221	-	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HKICGBDN_02367	0.0	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
HKICGBDN_02368	1.11e-175	-	-	-	-	-	-	-	-
HKICGBDN_02371	0.0	-	-	-	V	-	-	-	MatE
HKICGBDN_02372	4.33e-161	menG	2.1.1.163, 2.1.1.201	-	Q	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	ubiE/COQ5 methyltransferase family
HKICGBDN_02376	7.53e-201	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKICGBDN_02377	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKICGBDN_02378	1.3e-210	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKICGBDN_02379	3.95e-252	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKICGBDN_02381	1.37e-306	-	-	-	E	ko:K03310	-	ko00000	Sodium:alanine symporter family
HKICGBDN_02383	2.43e-95	-	-	-	K	-	-	-	-acetyltransferase
HKICGBDN_02384	8.6e-222	-	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Glutaminase
HKICGBDN_02385	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HKICGBDN_02389	6.63e-144	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKICGBDN_02390	5.87e-163	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HKICGBDN_02391	8.71e-301	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HKICGBDN_02392	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HKICGBDN_02394	3.29e-146	-	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKICGBDN_02395	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKICGBDN_02397	4.89e-237	-	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
HKICGBDN_02399	2.04e-160	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HKICGBDN_02400	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HKICGBDN_02401	1.72e-230	-	4.1.1.35	-	M	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	3-beta hydroxysteroid dehydrogenase/isomerase family
HKICGBDN_02402	2.15e-183	-	-	-	I	-	-	-	Acyl-ACP thioesterase
HKICGBDN_02403	6.37e-24	-	-	-	M	-	-	-	PFAM YD repeat-containing protein
HKICGBDN_02407	3.77e-138	nuoB	1.6.5.3	-	C	ko:K00331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKICGBDN_02408	3.49e-139	nuoC	1.6.5.3	-	C	ko:K00332	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HKICGBDN_02409	1.55e-164	-	-	-	-	-	-	-	-
HKICGBDN_02410	1.27e-70	-	-	-	K	-	-	-	ribonuclease III activity
HKICGBDN_02411	6.58e-276	-	6.2.1.26	-	IQ	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	AMP-binding enzyme
HKICGBDN_02413	0.0	-	-	-	S	ko:K07126,ko:K13582	ko04112,map04112	ko00000,ko00001	beta-lactamase activity
HKICGBDN_02414	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
HKICGBDN_02415	2.51e-06	-	-	-	-	-	-	-	-