ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MEDPMIKA_00001 7.56e-312 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MEDPMIKA_00002 0.0 lnt - GT2 M ko:K03820 - ko00000,ko01000 Carbon-nitrogen hydrolase
MEDPMIKA_00003 4.07e-274 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MEDPMIKA_00004 6.37e-40 - - - - - - - -
MEDPMIKA_00005 9.39e-59 - - - S - - - S1 P1 nuclease
MEDPMIKA_00007 1.28e-74 - - - - - - - -
MEDPMIKA_00009 5.41e-62 - - - S - - - Putative binding domain, N-terminal
MEDPMIKA_00010 3.36e-150 - - - Q ko:K21572 - ko00000,ko02000 pyridine nucleotide-disulphide oxidoreductase
MEDPMIKA_00011 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_00012 4.17e-56 - - - PT - - - Domain of unknown function (DUF4974)
MEDPMIKA_00013 2.04e-42 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor
MEDPMIKA_00014 1.63e-63 - - - T - - - Protein of unknown function (DUF3467)
MEDPMIKA_00015 4.11e-151 - - - E - - - LysE type translocator
MEDPMIKA_00016 3.36e-154 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MEDPMIKA_00017 1.16e-183 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MEDPMIKA_00018 1.19e-80 - - - - - - - -
MEDPMIKA_00019 0.0 prc 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MEDPMIKA_00020 7.78e-262 vicK - - T - - - histidine kinase DNA gyrase B
MEDPMIKA_00021 2.85e-107 - - - S - - - Domain of unknown function (DUF4271)
MEDPMIKA_00022 6.84e-176 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase HemD
MEDPMIKA_00023 2.36e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MEDPMIKA_00024 9.87e-58 yidD - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MEDPMIKA_00025 1.43e-180 czcD - - P ko:K16264 - ko00000,ko02000 Cation efflux family
MEDPMIKA_00026 4.72e-201 - - - D ko:K07322 - ko00000 Hemerythrin HHE cation binding domain
MEDPMIKA_00027 0.0 ltaS2 - - M - - - Psort location CytoplasmicMembrane, score 10.00
MEDPMIKA_00028 7.71e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Uracil phosphoribosyltransferase
MEDPMIKA_00029 2.8e-262 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MEDPMIKA_00030 4.04e-143 - - - U ko:K03832 - ko00000,ko02000 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MEDPMIKA_00031 3.64e-222 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MEDPMIKA_00032 4.13e-74 - - - CO - - - Protein of unknown function, DUF255
MEDPMIKA_00033 2.5e-130 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MEDPMIKA_00034 3.9e-119 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MEDPMIKA_00035 2.24e-246 - - - M - - - Psort location CytoplasmicMembrane, score
MEDPMIKA_00036 1.29e-273 tgt 2.4.2.29 - J ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MEDPMIKA_00038 4.77e-248 lptG - - S ko:K11720 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Predicted permease YjgP/YjgQ family
MEDPMIKA_00039 6.36e-183 spk1 2.7.11.1, 6.3.2.4 - S ko:K01921,ko:K08884,ko:K12132 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01001,ko01011 PASTA domain
MEDPMIKA_00040 3.79e-249 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MEDPMIKA_00041 0.0 - - - C - - - Domain of unknown function (DUF3362)
MEDPMIKA_00042 5.17e-275 - - - S - - - Conserved hypothetical protein 698
MEDPMIKA_00043 3.06e-206 - - - P - - - phosphate-selective porin O and P
MEDPMIKA_00044 5.13e-17 - - - - - - - -
MEDPMIKA_00045 1.67e-52 - - - - - - - -
MEDPMIKA_00048 1.39e-149 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MEDPMIKA_00049 1.93e-190 xerC - - D ko:K04763 - ko00000,ko03036 Tyrosine recombinase XerC
MEDPMIKA_00050 2.58e-18 - 3.5.4.40 - F ko:K20810 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Amidohydrolase family
MEDPMIKA_00051 8.39e-160 - - - - - - - -
MEDPMIKA_00052 1.44e-237 lolE - - M ko:K09808,ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 FtsX-like permease family
MEDPMIKA_00053 1.66e-64 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MEDPMIKA_00054 4.03e-173 - - - S - - - Outer membrane protein beta-barrel domain
MEDPMIKA_00055 0.0 - - - S - - - Bacterial Ig-like domain
MEDPMIKA_00057 7.27e-101 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MEDPMIKA_00058 8.61e-254 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III, delta subunit
MEDPMIKA_00060 3.62e-111 ppiA 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
MEDPMIKA_00061 0.0 cap - - S - - - Polysaccharide biosynthesis protein
MEDPMIKA_00062 7.38e-121 kdsC 3.1.3.45 - S ko:K03270 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase
MEDPMIKA_00063 2.86e-153 - - - S - - - NADP oxidoreductase coenzyme F420-dependent
MEDPMIKA_00064 1.58e-285 yihY - - S ko:K07058 - ko00000 Virulence factor BrkB
MEDPMIKA_00065 8.6e-225 - - - J - - - (SAM)-dependent
MEDPMIKA_00066 3.25e-282 - - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein
MEDPMIKA_00067 9.96e-80 - - - - - - - -
MEDPMIKA_00069 3.08e-74 - - - - - - - -
MEDPMIKA_00071 2.14e-279 - - - S - - - Phage portal protein
MEDPMIKA_00072 1.3e-190 - - - - - - - -
MEDPMIKA_00073 2.82e-158 - - - OU - - - Belongs to the peptidase S14 family
MEDPMIKA_00077 7.99e-99 mqnA 1.21.98.1, 4.2.1.151 - E ko:K07081,ko:K11782,ko:K11784 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
MEDPMIKA_00078 8.3e-227 corA - - P ko:K03284 - ko00000,ko02000 transport protein CorA
MEDPMIKA_00079 1.59e-100 asnC - - K ko:K03718 - ko00000,ko03000 Transcriptional regulator
MEDPMIKA_00080 3.47e-267 kbl 2.3.1.29 - H ko:K00639 ko00260,map00260 ko00000,ko00001,ko01000,ko01007 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA
MEDPMIKA_00081 5.92e-231 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 3-beta hydroxysteroid dehydrogenase/isomerase family
MEDPMIKA_00082 7.18e-114 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MEDPMIKA_00083 2.01e-121 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MEDPMIKA_00084 2.58e-83 hslR - - J ko:K04762 - ko00000,ko03110 S4 RNA-binding domain
MEDPMIKA_00085 4.46e-99 - - - CO - - - Antioxidant, AhpC TSA family
MEDPMIKA_00086 7.18e-275 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MEDPMIKA_00087 7.57e-303 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MEDPMIKA_00088 1.36e-269 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MEDPMIKA_00089 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEDPMIKA_00090 0.0 ftsI 3.4.16.4 - M ko:K03587 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Cell division protein FtsI
MEDPMIKA_00092 3.73e-195 rsmH 2.1.1.199 - H ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MEDPMIKA_00093 5.79e-181 - - - I - - - Phosphate acyltransferases
MEDPMIKA_00094 5.61e-227 - - - S - - - Acetyltransferase (GNAT) domain
MEDPMIKA_00095 1.66e-276 - - - - - - - -
MEDPMIKA_00097 3.39e-282 - - - T ko:K07713 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Sigma-54 interaction domain protein
MEDPMIKA_00098 0.0 - - - T - - - histidine kinase DNA gyrase B
MEDPMIKA_00099 8.57e-71 - - - - - - - -
MEDPMIKA_00100 6.03e-292 uhpC_2 - - G ko:K07783 ko02020,map02020 ko00000,ko00001,ko02000 Transporter, major facilitator family protein
MEDPMIKA_00101 5.08e-172 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
MEDPMIKA_00102 8.37e-205 natA - - S ko:K01990 - ko00000,ko00002,ko02000 Domain of unknown function (DUF4162)
MEDPMIKA_00103 3.44e-253 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MEDPMIKA_00104 1.6e-287 pgk 2.7.2.3 - G ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MEDPMIKA_00105 0.0 pepO 3.4.24.71 - O ko:K01415,ko:K07386 - ko00000,ko01000,ko01002,ko04147 Peptidase family M13
MEDPMIKA_00106 8.74e-177 - - - T - - - His Kinase A (phosphoacceptor) domain
MEDPMIKA_00107 0.0 - - - T - - - His Kinase A (phosphoacceptor) domain
MEDPMIKA_00108 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_00109 0.0 - - - K ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_00110 1.39e-270 - - - S ko:K21571 - ko00000 SusE outer membrane protein
MEDPMIKA_00111 0.0 - - - G - - - COG NOG23094 non supervised orthologous group
MEDPMIKA_00112 0.0 - - - Q - - - COG NOG08355 non supervised orthologous group
MEDPMIKA_00113 1.48e-113 - - - S - - - Domain of unknown function (DUF5040)
MEDPMIKA_00114 0.0 - - - G - - - Melibiase
MEDPMIKA_00115 0.0 - 3.2.1.31 - G ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 2, sugar binding domain protein
MEDPMIKA_00116 2.42e-245 - - - G - - - Glycosyl Hydrolase Family 88
MEDPMIKA_00117 2.03e-255 - - - S - - - alpha beta
MEDPMIKA_00118 0.0 - - - G - - - Belongs to the glycosyl hydrolase 2 family
MEDPMIKA_00119 3.77e-133 - 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 35 family
MEDPMIKA_00120 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
MEDPMIKA_00121 2.84e-254 - - - G - - - Glycosyl hydrolases family 43
MEDPMIKA_00122 1.81e-136 - - - G - - - Belongs to the glycosyl hydrolase 43 family
MEDPMIKA_00123 6.07e-29 - - - G - - - Belongs to the glycosyl hydrolase 43 family
MEDPMIKA_00124 0.0 - - - M ko:K07001 - ko00000 Patatin-like phospholipase
MEDPMIKA_00125 4.63e-231 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MEDPMIKA_00126 0.0 - - - S - - - Tetratricopeptide repeat
MEDPMIKA_00127 2.06e-177 envC - - D - - - peptidase
MEDPMIKA_00128 1e-96 ybeY - - S - - - Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MEDPMIKA_00130 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MEDPMIKA_00131 2.65e-217 ilvE 2.6.1.42 - EH ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Amino-transferase class IV
MEDPMIKA_00132 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MEDPMIKA_00133 0.0 dpp11 - - E - - - Peptidase S46
MEDPMIKA_00134 4.49e-208 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MEDPMIKA_00136 1.72e-226 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MEDPMIKA_00137 0.0 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 Peptidase family S49
MEDPMIKA_00138 4.96e-15 - - - K - - - helix_turn_helix, arabinose operon control protein
MEDPMIKA_00139 2.74e-91 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
MEDPMIKA_00140 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MEDPMIKA_00141 1.37e-208 gpr - - C ko:K19265 - ko00000,ko01000 Aldo/keto reductase family
MEDPMIKA_00142 3.17e-142 - - - M - - - COG NOG27406 non supervised orthologous group
MEDPMIKA_00143 1.02e-145 - - - S - - - COG NOG26965 non supervised orthologous group
MEDPMIKA_00144 0.0 - - - S - - - Tetratricopeptide repeat
MEDPMIKA_00145 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
MEDPMIKA_00146 0.0 - - - C - - - C terminal of Calcineurin-like phosphoesterase
MEDPMIKA_00147 0.0 - - - S ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_00148 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_00149 2.07e-292 - - - U - - - domain, Protein
MEDPMIKA_00150 7.08e-73 - - - U - - - domain, Protein
MEDPMIKA_00151 3.09e-140 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
MEDPMIKA_00152 9.92e-218 - - - S - - - Oxidoreductase NAD-binding domain protein
MEDPMIKA_00153 7.32e-136 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MEDPMIKA_00154 7.38e-97 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MEDPMIKA_00155 9.2e-82 - - - - - - - -
MEDPMIKA_00156 3.61e-192 - - - E - - - haloacid dehalogenase-like hydrolase
MEDPMIKA_00157 9.62e-103 - - - C - - - Nitroreductase family
MEDPMIKA_00158 0.0 - - - T - - - Psort location CytoplasmicMembrane, score
MEDPMIKA_00159 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 DHH family
MEDPMIKA_00160 1e-138 lipB 2.3.1.181 - H ko:K03801 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate
MEDPMIKA_00161 4.17e-203 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MEDPMIKA_00163 1.93e-203 - - - K - - - helix_turn_helix, arabinose operon control protein
MEDPMIKA_00165 6.7e-135 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEDPMIKA_00166 1.52e-98 - - - U ko:K03559 - ko00000,ko02000 Biopolymer transport protein ExbD/TolR
MEDPMIKA_00167 7.55e-117 - - - U - - - Biopolymer transport protein ExbD/TolR
MEDPMIKA_00169 5.82e-142 exbB - - U ko:K03561 - ko00000,ko02000 MotA TolQ ExbB proton channel family
MEDPMIKA_00170 1.03e-223 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
MEDPMIKA_00171 7.15e-52 - - - S - - - COG NOG16854 non supervised orthologous group
MEDPMIKA_00172 2.88e-164 tatD - - L ko:K03424 - ko00000,ko01000 TatD related DNase
MEDPMIKA_00173 3.43e-241 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MEDPMIKA_00175 6.05e-21 - - - - - - - -
MEDPMIKA_00176 0.0 - - - V - - - T5orf172
MEDPMIKA_00177 1.68e-223 - - - V - - - AAA domain
MEDPMIKA_00178 1.86e-225 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Eco57I restriction-modification methylase
MEDPMIKA_00179 1.04e-71 - - - V - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_00180 1.26e-293 - - - S - - - Plasmid recombination enzyme
MEDPMIKA_00181 1.96e-197 - - - L - - - Toprim-like
MEDPMIKA_00182 8.62e-59 - - - L - - - Helix-turn-helix domain
MEDPMIKA_00183 9.44e-54 - - - S - - - Competence protein CoiA-like family
MEDPMIKA_00185 2.36e-209 - - - K - - - Putative ATP-dependent DNA helicase recG C-terminal
MEDPMIKA_00186 5.6e-289 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_00187 1.11e-86 - 3.1.6.1 - P ko:K01130 ko00140,ko00600,map00140,map00600 ko00000,ko00001,ko01000 Sulfatase
MEDPMIKA_00188 0.0 yhgF - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain
MEDPMIKA_00189 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Glycosyl hydrolase family 36 N-terminal domain
MEDPMIKA_00190 0.0 - - - P - - - Outer membrane protein beta-barrel family
MEDPMIKA_00191 7.56e-207 - - - P - - - TonB dependent receptor
MEDPMIKA_00192 6.74e-21 - - - S - - - Protein of unknown function (DUF4876)
MEDPMIKA_00194 3.39e-308 - - - E - - - Peptidase S46
MEDPMIKA_00195 1.07e-285 - - - C - - - 4Fe-4S binding domain
MEDPMIKA_00196 1.1e-165 - - - S ko:K07263 - ko00000,ko01000,ko01002 Belongs to the peptidase M16 family
MEDPMIKA_00197 2.56e-307 - 3.2.1.20 GH31 M ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl-hydrolase 97 C-terminal, oligomerisation
MEDPMIKA_00198 0.0 - - - P - - - Outer membrane protein beta-barrel family
MEDPMIKA_00199 4.95e-307 atsB - - C ko:K06871 - ko00000 Iron-sulfur cluster-binding domain
MEDPMIKA_00200 1.36e-162 aldH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MEDPMIKA_00201 1.93e-223 batB - - S ko:K07114 - ko00000,ko02000 Von Willebrand factor type A domain
MEDPMIKA_00202 9.43e-206 batA - - S ko:K07114 - ko00000,ko02000 von Willebrand factor type A domain
MEDPMIKA_00203 3.48e-36 - - - S - - - 23S rRNA-intervening sequence protein
MEDPMIKA_00204 1.79e-67 batC - - S - - - Tetratricopeptide repeat
MEDPMIKA_00205 5.08e-201 - - - O - - - Psort location CytoplasmicMembrane, score
MEDPMIKA_00206 2.39e-198 - - - S - - - Protein of unknown function DUF58
MEDPMIKA_00207 8.25e-225 moxR - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
MEDPMIKA_00209 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 UvrD-like helicase C-terminal domain
MEDPMIKA_00210 3.62e-217 - - - M - - - Glycosyltransferase, group 2 family
MEDPMIKA_00211 7.78e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MEDPMIKA_00212 4.25e-174 - - - E - - - Pkd domain containing protein
MEDPMIKA_00213 1.69e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHH family
MEDPMIKA_00214 8.91e-167 cysL - - K - - - LysR substrate binding domain
MEDPMIKA_00215 3.26e-220 - - - S - - - Belongs to the UPF0324 family
MEDPMIKA_00216 3.87e-117 - - - K - - - Acetyltransferase (GNAT) domain
MEDPMIKA_00217 7.77e-131 - - - PT - - - Domain of unknown function (DUF4974)
MEDPMIKA_00218 0.0 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_00219 7.51e-138 - - - K - - - Psort location Cytoplasmic, score
MEDPMIKA_00220 1.69e-236 - - - S - - - hmm pf08843
MEDPMIKA_00222 1.69e-65 - - - K - - - Helix-turn-helix domain
MEDPMIKA_00223 1.8e-202 virE2 - - S - - - Virulence-associated protein E
MEDPMIKA_00224 3.68e-201 - - - L - - - Toprim-like
MEDPMIKA_00225 2.79e-13 - - - S - - - Bacterial mobilisation protein (MobC)
MEDPMIKA_00226 2.78e-219 - - - U - - - Relaxase mobilization nuclease domain protein
MEDPMIKA_00227 1.09e-89 - - - - - - - -
MEDPMIKA_00228 5.77e-45 - - - K ko:K02529 - ko00000,ko03000 Psort location Cytoplasmic, score
MEDPMIKA_00229 6.27e-153 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MEDPMIKA_00230 1.05e-288 - - - H - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_00231 1.71e-133 - - - P ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_00233 5.11e-129 - - - S - - - C terminal of Calcineurin-like phosphoesterase
MEDPMIKA_00234 6.49e-260 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Alpha galactosidase A
MEDPMIKA_00235 1.12e-185 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
MEDPMIKA_00236 3.91e-303 - - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
MEDPMIKA_00237 6.88e-158 - - - I - - - alpha/beta hydrolase fold
MEDPMIKA_00240 0.0 - - - E - - - peptidase S46
MEDPMIKA_00241 1.36e-91 maf - - D ko:K06287 - ko00000 Maf-like protein
MEDPMIKA_00242 1.02e-144 fahA - - Q - - - FAH family
MEDPMIKA_00243 2.06e-45 - - - S - - - Domain of unknown function (DUF3784)
MEDPMIKA_00244 9.43e-243 lpxB 2.4.1.182 GT19 M ko:K00748 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MEDPMIKA_00245 6.89e-159 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MEDPMIKA_00246 8.05e-151 - - - O - - - Methyltransferase FkbM domain
MEDPMIKA_00247 1.28e-155 - - - P - - - Metallo-beta-lactamase superfamily
MEDPMIKA_00248 4.57e-176 - - - I - - - COG0657 Esterase lipase
MEDPMIKA_00249 1.07e-222 - - - - - - - -
MEDPMIKA_00250 0.0 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEDPMIKA_00251 7.63e-32 - - - M - - - Peptidase family M23
MEDPMIKA_00252 1.04e-132 - - - S ko:K09807 - ko00000 Protein of unknown function (DUF541)
MEDPMIKA_00253 1.84e-95 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 cytidine deaminase
MEDPMIKA_00254 1.05e-162 rluC 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Pseudouridine synthase, RluA family
MEDPMIKA_00255 1.76e-88 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MEDPMIKA_00256 2.36e-119 - - - F - - - DNA/RNA non-specific endonuclease
MEDPMIKA_00257 2.12e-206 - - - S ko:K07139 - ko00000 Radical SAM protein
MEDPMIKA_00258 1.01e-196 - - - S - - - Psort location CytoplasmicMembrane, score
MEDPMIKA_00259 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MEDPMIKA_00260 2.91e-147 comF 2.4.2.14 - S ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Phosphoribosyl transferase domain
MEDPMIKA_00261 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MEDPMIKA_00262 0.0 comM - - O ko:K07391 - ko00000 Magnesium chelatase, subunit ChlI C-terminal
MEDPMIKA_00263 5.55e-247 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MEDPMIKA_00264 1.22e-293 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MEDPMIKA_00265 4.07e-210 ftsQ - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MEDPMIKA_00266 2.47e-272 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MEDPMIKA_00267 3.45e-271 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MEDPMIKA_00268 3.66e-227 gldE - - S - - - Gliding motility-associated protein GldE
MEDPMIKA_00269 8.32e-87 sfp - - H - - - 4'-phosphopantetheinyl transferase superfamily
MEDPMIKA_00270 5.86e-308 - - - M - - - non supervised orthologous group
MEDPMIKA_00271 2.85e-11 - - - S - - - Pentapeptide repeat protein
MEDPMIKA_00272 3.75e-268 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MEDPMIKA_00273 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MEDPMIKA_00274 6.69e-266 - - - S - - - Domain of unknown function (DUF4270)
MEDPMIKA_00275 2.29e-183 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Starch synthase catalytic domain
MEDPMIKA_00276 1.45e-238 queA 2.4.99.17 - H ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MEDPMIKA_00277 9.49e-155 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MEDPMIKA_00278 3.54e-164 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MEDPMIKA_00279 7.96e-48 fjo13 - - S - - - Psort location CytoplasmicMembrane, score 9.82
MEDPMIKA_00280 1.39e-169 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily
MEDPMIKA_00281 0.0 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
MEDPMIKA_00286 1.64e-84 - - - K - - - WYL domain
MEDPMIKA_00287 4.06e-06 - - - L - - - Phage integrase family
MEDPMIKA_00288 1.18e-211 ispB 2.5.1.90 - H ko:K02523 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MEDPMIKA_00289 1.47e-271 gluP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
MEDPMIKA_00291 3.65e-30 - - - S - - - Phage prohead protease, HK97 family
MEDPMIKA_00293 3.91e-112 - - - - - - - -
MEDPMIKA_00296 6.92e-41 - - - K - - - Peptidase S24-like
MEDPMIKA_00297 2.42e-79 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MEDPMIKA_00298 5.94e-164 surE 3.1.3.5 - S ko:K03787 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MEDPMIKA_00299 9.39e-210 - - - T - - - histidine kinase DNA gyrase B
MEDPMIKA_00300 2.47e-134 - - - KT - - - helix_turn_helix, Lux Regulon
MEDPMIKA_00301 1.57e-313 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEDPMIKA_00302 7.37e-207 - - - L - - - Domain of unknown function (DUF4837)
MEDPMIKA_00303 1.05e-138 pgdA_1 - - G - - - Polysaccharide deacetylase
MEDPMIKA_00304 1.66e-125 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MEDPMIKA_00305 0.0 - - - P - - - N-terminal domain of unknown function (DUF4140)
MEDPMIKA_00306 3.91e-287 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Lyase
MEDPMIKA_00307 1.25e-214 argE 3.5.1.16 - E ko:K01438 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
MEDPMIKA_00308 8.35e-160 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
MEDPMIKA_00309 3.11e-222 argF 2.1.3.11, 2.1.3.9 - E ko:K09065,ko:K13043 ko00220,ko01100,ko01230,map00220,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MEDPMIKA_00310 3.06e-244 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
MEDPMIKA_00311 1.3e-199 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MEDPMIKA_00312 1.4e-281 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Arginosuccinate synthase
MEDPMIKA_00313 5.31e-149 - - - E - - - Acetyltransferase (GNAT) family
MEDPMIKA_00314 0.0 relA 2.7.6.5, 3.1.7.2 - KT ko:K00951,ko:K01139 ko00230,map00230 ko00000,ko00001,ko01000,ko03009 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MEDPMIKA_00315 2.44e-135 hly-III - - S ko:K11068 - ko00000,ko02042 membrane protein, hemolysin III homolog
MEDPMIKA_00316 2.4e-185 - 3.1.3.97 - S ko:K07053 - ko00000,ko01000 DNA polymerase alpha chain like domain
MEDPMIKA_00317 9.38e-180 rebM - - Q - - - Methyltransferase
MEDPMIKA_00318 1.76e-27 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEDPMIKA_00319 9.98e-240 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEDPMIKA_00320 8.81e-192 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
MEDPMIKA_00321 2.77e-82 - - - M ko:K03832 - ko00000,ko02000 energy transducer activity
MEDPMIKA_00322 1.57e-47 ogt 2.1.1.63 - L ko:K00567,ko:K07443 - ko00000,ko01000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain protein
MEDPMIKA_00323 1.14e-271 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEDPMIKA_00324 1.11e-207 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Phosphate acetyl/butaryl transferase
MEDPMIKA_00325 4.28e-234 buk 2.7.2.7 - H ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
MEDPMIKA_00327 4.15e-06 - - - K - - - helix_turn_helix, arabinose operon control protein
MEDPMIKA_00328 2.29e-273 - - - S - - - Polysaccharide biosynthesis protein
MEDPMIKA_00329 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase, barrel domain
MEDPMIKA_00330 1.15e-83 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
MEDPMIKA_00331 2.09e-185 - 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MEDPMIKA_00332 1.17e-47 - - - D - - - Septum formation initiator
MEDPMIKA_00333 2.92e-144 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MEDPMIKA_00334 1.86e-109 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MEDPMIKA_00339 1.67e-311 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_00341 0.0 - - - S - - - Domain of unknown function (DUF4091)
MEDPMIKA_00342 0.0 - - - S - - - protein conserved in bacteria
MEDPMIKA_00343 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3 C-terminal domain
MEDPMIKA_00344 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEDPMIKA_00345 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
MEDPMIKA_00346 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
MEDPMIKA_00347 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 hydrolase, family 3
MEDPMIKA_00348 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
MEDPMIKA_00349 7.03e-270 - - - S - - - Domain of unknown function (DUF5009)
MEDPMIKA_00350 0.0 - 3.2.1.20 GH31 S ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase 97
MEDPMIKA_00351 0.0 kojP - - G - - - Glycosyl hydrolase family 65 central catalytic domain
MEDPMIKA_00352 2.85e-207 - - - S - - - Endonuclease/Exonuclease/phosphatase family
MEDPMIKA_00353 3.36e-224 - 3.1.3.16 - S ko:K21814 - ko00000,ko01000,ko01009 Calcineurin-like phosphoesterase superfamily domain
MEDPMIKA_00354 0.0 - - - P - - - CarboxypepD_reg-like domain
MEDPMIKA_00355 0.0 - - - P ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_00356 2.45e-214 - - - S - - - F5 8 type C domain
MEDPMIKA_00357 0.0 celC 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 5 (cellulase A) family
MEDPMIKA_00358 0.0 - - - G - - - Belongs to the glycosyl hydrolase 28 family
MEDPMIKA_00359 0.0 - - - G - - - Belongs to the glycosyl hydrolase 28 family
MEDPMIKA_00360 0.0 - - - M - - - polygalacturonase activity
MEDPMIKA_00361 7.61e-76 - - - M - - - polygalacturonase activity
MEDPMIKA_00362 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
MEDPMIKA_00363 8.08e-119 rnfA - - C ko:K03617 - ko00000 Part of a membrane complex involved in electron transport
MEDPMIKA_00364 3.66e-116 rnfE - - C ko:K03613 - ko00000 Part of a membrane complex involved in electron transport
MEDPMIKA_00365 9.44e-115 rnfG - - C ko:K03612 - ko00000 Part of a membrane complex involved in electron transport
MEDPMIKA_00366 2.51e-185 rnfD - - C ko:K03614 - ko00000 Part of a membrane complex involved in electron transport
MEDPMIKA_00367 7.15e-281 rnfC - - C ko:K03615 - ko00000 Part of a membrane complex involved in electron transport
MEDPMIKA_00368 2.15e-197 rnfB - - C ko:K03616 - ko00000 electron transport complex, RnfABCDGE type, B subunit
MEDPMIKA_00369 1.03e-68 - - - T ko:K03803 - ko00000,ko03021 Positive regulator of sigma(E), RseC MucC
MEDPMIKA_00370 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD synthetase family
MEDPMIKA_00371 4.4e-130 - - - S ko:K07164 - ko00000 Zinc ribbon domain
MEDPMIKA_00372 5.41e-163 yqfO - - S - - - Dinuclear metal center protein
MEDPMIKA_00373 1.53e-78 ycgE - - K - - - helix_turn_helix, mercury resistance
MEDPMIKA_00374 3.31e-285 rsmF - - J - - - RNA-binding PUA-like domain of methyltransferase RsmF
MEDPMIKA_00375 2.82e-141 dck - - F - - - Deoxynucleoside kinase
MEDPMIKA_00376 0.0 - - - H - - - GH3 auxin-responsive promoter
MEDPMIKA_00377 9.08e-298 trkA - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
MEDPMIKA_00378 4.04e-12 - - - - - - - -
MEDPMIKA_00379 4.45e-186 cysQ 3.1.3.7 - P ko:K01082 ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130 ko00000,ko00001,ko01000,ko03016 Inositol monophosphatase family
MEDPMIKA_00380 2.25e-123 ugcG 2.4.1.80 GT21 M ko:K00720 ko00600,ko01100,map00600,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko02000 transferase activity, transferring glycosyl groups
MEDPMIKA_00382 3.06e-08 ompR - - K ko:K07659 ko02020,ko02026,map02020,map02026 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEDPMIKA_00383 3.38e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MEDPMIKA_00384 1.35e-55 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MEDPMIKA_00385 5.27e-14 - - - K - - - Helix-turn-helix XRE-family like proteins
MEDPMIKA_00386 4.02e-75 - - - O - - - META domain
MEDPMIKA_00387 0.0 nifJ 1.2.7.1 - C ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
MEDPMIKA_00388 1.38e-261 - - - S ko:K07263 - ko00000,ko01000,ko01002 Peptidase M16 inactive domain
MEDPMIKA_00389 1.75e-244 - - - S - - - Peptidase M16 inactive domain
MEDPMIKA_00390 7e-171 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MEDPMIKA_00391 8.38e-10 - - - - - - - -
MEDPMIKA_00395 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MEDPMIKA_00396 6.74e-174 lptB - - S ko:K06861 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MEDPMIKA_00397 1.05e-250 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MEDPMIKA_00398 3.62e-204 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MEDPMIKA_00399 1.58e-145 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MEDPMIKA_00400 4.02e-90 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
MEDPMIKA_00401 4.19e-310 - - - M - - - Peptidase family M23
MEDPMIKA_00402 4.15e-76 divK - - T - - - Response regulator receiver domain
MEDPMIKA_00404 1.16e-87 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MEDPMIKA_00405 3.27e-96 rimM - - J ko:K02860 - ko00000,ko03009 ribosome binding
MEDPMIKA_00406 9.28e-255 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MEDPMIKA_00407 3.68e-236 - - - E - - - N-terminus of Esterase_SGNH_hydro-type
MEDPMIKA_00409 3.45e-17 - - - K - - - Helix-turn-helix XRE-family like proteins
MEDPMIKA_00410 8.81e-148 - - - - - - - -
MEDPMIKA_00411 0.0 ppdK 2.7.9.1 - G ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the PEP-utilizing enzyme family
MEDPMIKA_00412 1.75e-67 - - - M ko:K11934 - ko00000,ko02000 Outer membrane protein beta-barrel domain
MEDPMIKA_00413 3.59e-97 - - - - - - - -
MEDPMIKA_00414 1.15e-58 - - - S - - - TRL-like protein family
MEDPMIKA_00415 2.3e-124 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEDPMIKA_00416 2.53e-89 ruvX - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MEDPMIKA_00417 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
MEDPMIKA_00418 8.88e-24 - - - S - - - Putative binding domain, N-terminal
MEDPMIKA_00419 5.83e-111 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
MEDPMIKA_00420 2.33e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MEDPMIKA_00421 1.82e-295 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MEDPMIKA_00422 8.7e-44 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEDPMIKA_00423 2.68e-160 pepE 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
MEDPMIKA_00424 2.86e-183 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydrogenase
MEDPMIKA_00425 4.58e-68 - - - L ko:K07460 - ko00000 Belongs to the UPF0102 family
MEDPMIKA_00426 4.51e-281 waaA 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 M ko:K02527 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase)
MEDPMIKA_00427 5.01e-203 - - - S - - - COG NOG28036 non supervised orthologous group
MEDPMIKA_00428 1.24e-233 - - - G - - - Histidine acid phosphatase
MEDPMIKA_00429 1.6e-252 - - - S - - - Belongs to the UPF0597 family
MEDPMIKA_00430 1.48e-117 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Hydrolase, NUDIX family
MEDPMIKA_00431 4.23e-128 - - - C - - - Nitroreductase family
MEDPMIKA_00433 1.8e-150 - - - C - - - 4Fe-4S dicluster domain
MEDPMIKA_00434 5.4e-47 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase, gnat family
MEDPMIKA_00435 1.29e-76 hsp20 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MEDPMIKA_00436 4.39e-49 wecD - - M - - - Acetyltransferase (GNAT) family
MEDPMIKA_00440 6.27e-14 - - - - - - - -
MEDPMIKA_00441 9.9e-96 - - - M - - - Domain of unknown function
MEDPMIKA_00446 8.72e-97 - - - - - - - -
MEDPMIKA_00447 6.93e-281 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_00449 4.29e-25 - - - S ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_00450 2.99e-311 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_00451 1.77e-223 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_00452 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_00453 8.03e-106 - - - S - - - Pfam:SusD
MEDPMIKA_00455 4.54e-219 - - - O - - - Peptidase, S8 S53 family
MEDPMIKA_00457 1.52e-264 fprA 1.6.3.4 - C ko:K22405 - ko00000,ko01000 Metallo-beta-lactamase domain protein
MEDPMIKA_00458 4.36e-285 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MEDPMIKA_00459 6.41e-252 mmdB 4.1.1.3, 4.3.99.2 - C ko:K01572,ko:K20509 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Na+-transporting oxaloacetate decarboxylase beta subunit
MEDPMIKA_00462 2.53e-83 tabA_2 - - G - - - YhcH YjgK YiaL family
MEDPMIKA_00463 7.24e-283 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
MEDPMIKA_00464 1.21e-148 dcp 3.4.15.5 - E ko:K01284 - ko00000,ko01000,ko01002 Peptidase family M3
MEDPMIKA_00465 2.03e-217 - - - S - - - Endonuclease/Exonuclease/phosphatase family
MEDPMIKA_00466 1.85e-137 - 3.4.21.105 - S ko:K09650 - ko00000,ko01000,ko01002,ko03029 Rhomboid family
MEDPMIKA_00467 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MEDPMIKA_00468 2.49e-58 - - - - - - - -
MEDPMIKA_00469 2.28e-230 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MEDPMIKA_00470 1.38e-105 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MEDPMIKA_00471 2.93e-146 rsmI_1 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase, YraL family
MEDPMIKA_00472 0.0 alr 5.1.1.1, 6.3.2.10 - M ko:K01775,ko:K01929 ko00300,ko00473,ko00550,ko01100,ko01502,map00300,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MEDPMIKA_00473 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MEDPMIKA_00474 3.16e-184 - - - Q ko:K02067 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 virulence factor Mce family protein
MEDPMIKA_00475 4.49e-184 amiA 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
MEDPMIKA_00476 0.0 - - - M - - - Psort location OuterMembrane, score
MEDPMIKA_00480 7.09e-123 - - - F ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 DNA/RNA non-specific endonuclease
MEDPMIKA_00481 3.01e-154 - - - C - - - Nitroreductase family
MEDPMIKA_00482 1.85e-283 nupG - - G ko:K03289,ko:K11537 - ko00000,ko02000 transport of nucleosides, permease protein K03289
MEDPMIKA_00484 1.21e-110 - - - S - - - Endonuclease/Exonuclease/phosphatase family
MEDPMIKA_00485 7.7e-57 - - - - - - - -
MEDPMIKA_00486 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_00487 6.42e-180 - - - S ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_00488 1.28e-45 - - - - - - - -
MEDPMIKA_00489 2.24e-133 - - - - - - - -
MEDPMIKA_00490 3.04e-65 - - - S - - - C terminal of Calcineurin-like phosphoesterase
MEDPMIKA_00492 1.53e-188 - - - S - - - phosphatase family
MEDPMIKA_00493 0.0 - - - S ko:K21572 - ko00000,ko02000 RagB SusD family protein
MEDPMIKA_00494 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_00495 2.65e-162 - - - PT - - - COG3712 Fe2 -dicitrate sensor, membrane component
MEDPMIKA_00496 1.66e-84 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor
MEDPMIKA_00497 1.75e-104 - - - - - - - -
MEDPMIKA_00498 0.0 dcp 3.4.15.5, 3.4.24.70 - E ko:K01284,ko:K01414 - ko00000,ko01000,ko01002 Peptidase family M3
MEDPMIKA_00499 0.0 dcp 3.4.15.5 - E ko:K01284 - ko00000,ko01000,ko01002 Peptidase family M3
MEDPMIKA_00500 3.98e-132 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MEDPMIKA_00501 0.0 - - - CP ko:K12137 - ko00000,ko01000 Proton-conducting membrane transporter
MEDPMIKA_00502 7.55e-161 - - - C - - - NADH dehydrogenase
MEDPMIKA_00503 2.65e-114 - - - C ko:K12140 - ko00000,ko01000 Hydrogenase 4 membrane
MEDPMIKA_00505 8.14e-308 - - - C - - - Respiratory-chain NADH dehydrogenase, 49 Kd subunit
MEDPMIKA_00506 2.26e-151 - - - C - - - NADH ubiquinone oxidoreductase, 20 Kd subunit
MEDPMIKA_00507 5.97e-93 - - - P ko:K07240 - ko00000,ko02000 Chromate transporter
MEDPMIKA_00508 2.08e-120 - - - P ko:K07240 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
MEDPMIKA_00509 4.71e-99 - - - - - - - -
MEDPMIKA_00511 9.34e-189 - 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
MEDPMIKA_00512 0.0 prtQ - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Collagenase
MEDPMIKA_00514 2.97e-100 - - - S ko:K21449 - ko00000,ko02000 Bacterial surface protein 26-residue PARCEL
MEDPMIKA_00515 5.55e-116 - - - S ko:K21449 - ko00000,ko02000 Bacterial surface protein 26-residue PARCEL
MEDPMIKA_00516 1.05e-113 - - - - - - - -
MEDPMIKA_00517 0.0 - - - O - - - Peptidase, S8 S53 family
MEDPMIKA_00519 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_00520 1.29e-307 - - - E ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_00522 6.58e-293 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Seryl-tRNA synthetase N-terminal domain
MEDPMIKA_00523 9.16e-18 - - - C - - - 4Fe-4S binding domain
MEDPMIKA_00524 1.62e-94 maa 2.3.1.18, 2.3.1.79 - K ko:K00633,ko:K00661 - ko00000,ko01000 Bacterial transferase hexapeptide repeat protein
MEDPMIKA_00525 1.04e-24 - - - L ko:K07461 - ko00000 GIY-YIG catalytic domain
MEDPMIKA_00526 9.17e-246 - - - S - - - Protein of unknown function (DUF1343)
MEDPMIKA_00528 2.53e-245 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MEDPMIKA_00529 4.36e-125 - - - F - - - Cytidylate kinase-like family
MEDPMIKA_00530 6.08e-306 - - - V - - - Polysaccharide biosynthesis C-terminal domain
MEDPMIKA_00532 1.98e-57 ydjH_1 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family
MEDPMIKA_00533 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MEDPMIKA_00534 5.45e-236 rhlE 3.6.4.13 - L ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Belongs to the DEAD box helicase family
MEDPMIKA_00535 0.0 - - - P - - - Protein of unknown function (DUF2723)
MEDPMIKA_00536 2.08e-240 asnA 6.3.1.1 - E ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 Aspartate-ammonia ligase
MEDPMIKA_00537 0.0 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 Long-chain acyl-CoA synthetase
MEDPMIKA_00538 6.42e-181 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Domain of unknown function (DUF1730)
MEDPMIKA_00539 2.14e-175 - - - S - - - Tetratricopeptide repeat
MEDPMIKA_00540 3.88e-91 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MEDPMIKA_00541 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_00542 1.23e-217 - - - P ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_00544 4.09e-186 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MEDPMIKA_00545 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Alpha-galactosidase
MEDPMIKA_00546 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MEDPMIKA_00547 1.68e-22 - - - U - - - Relaxase/Mobilisation nuclease domain
MEDPMIKA_00548 1.78e-116 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma factor
MEDPMIKA_00549 2.78e-197 - - - PT - - - Domain of unknown function (DUF4974)
MEDPMIKA_00550 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_00551 0.0 - - - S ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_00552 5.63e-247 - - - S - - - Endonuclease Exonuclease Phosphatase
MEDPMIKA_00553 3.79e-237 - - - C - - - C terminal of Calcineurin-like phosphoesterase
MEDPMIKA_00554 0.0 - - - P - - - Sulfatase
MEDPMIKA_00555 3.83e-132 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
MEDPMIKA_00556 1.78e-302 uhpC_2 - - G ko:K07783 ko02020,map02020 ko00000,ko00001,ko02000 Transporter, major facilitator family protein
MEDPMIKA_00558 4.79e-46 - - - - - - - -
MEDPMIKA_00559 6.31e-191 - - - G ko:K02566 - ko00000 Haloacid dehalogenase-like hydrolase
MEDPMIKA_00560 1.14e-233 - - - S - - - Calcineurin-like phosphoesterase
MEDPMIKA_00561 5.53e-284 - 1.1.1.261 - C ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
MEDPMIKA_00562 0.0 - - - G ko:K07783 ko02020,map02020 ko00000,ko00001,ko02000 Major Facilitator Superfamily
MEDPMIKA_00563 9.93e-168 - - - K ko:K02081 - ko00000,ko03000 DeoR C terminal sensor domain
MEDPMIKA_00564 2.66e-274 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MEDPMIKA_00565 2.25e-256 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
MEDPMIKA_00566 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
MEDPMIKA_00567 5.81e-166 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MEDPMIKA_00568 1.2e-209 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MEDPMIKA_00569 1.31e-154 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MEDPMIKA_00570 6.46e-54 - - - CO - - - Glutaredoxin
MEDPMIKA_00571 8.9e-192 - - - M - - - Peptidase family S41
MEDPMIKA_00572 1.33e-137 pyrE 2.4.2.10, 4.1.1.23 - F ko:K00762,ko:K13421 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MEDPMIKA_00573 1.26e-245 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MEDPMIKA_00574 0.0 - - - G - - - Alpha-1,2-mannosidase
MEDPMIKA_00575 8.85e-90 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MEDPMIKA_00576 2.5e-239 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MEDPMIKA_00577 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphoribosylformylglycinamidine synthase
MEDPMIKA_00578 3.97e-182 - - - S - - - Endonuclease/Exonuclease/phosphatase family
MEDPMIKA_00579 2.77e-160 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylaminoimidazolesuccinocarboxamide synthase
MEDPMIKA_00580 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MEDPMIKA_00581 9.76e-233 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MEDPMIKA_00582 2.44e-117 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MEDPMIKA_00583 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MEDPMIKA_00584 1.27e-286 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MEDPMIKA_00585 3.94e-182 folD 1.5.1.5, 3.5.4.9 - E ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MEDPMIKA_00587 3.66e-289 - - - S ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_00588 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_00589 5.56e-244 - - - S - - - C terminal of Calcineurin-like phosphoesterase
MEDPMIKA_00591 4.24e-306 - - - S ko:K01163 - ko00000 Psort location Cytoplasmic, score 8.96
MEDPMIKA_00592 0.0 - - - M - - - Sulfatase
MEDPMIKA_00593 2.6e-197 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
MEDPMIKA_00595 0.0 - - - P - - - TonB dependent receptor
MEDPMIKA_00596 2.6e-101 - - - K - - - Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEDPMIKA_00597 4.98e-96 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MEDPMIKA_00598 4.62e-162 - - - S - - - S1 P1 nuclease
MEDPMIKA_00599 2.68e-308 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MEDPMIKA_00600 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 tRNA synthetases class II (D, K and N)
MEDPMIKA_00601 1.67e-307 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 RNA polymerase sigma54 factor
MEDPMIKA_00602 7.96e-124 - - - I - - - Psort location CytoplasmicMembrane, score 10.00
MEDPMIKA_00603 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
MEDPMIKA_00604 3.33e-82 - - - S - - - COG NOG28221 non supervised orthologous group
MEDPMIKA_00605 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MEDPMIKA_00606 9.17e-284 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MEDPMIKA_00607 0.0 - - - S - - - OPT oligopeptide transporter protein
MEDPMIKA_00608 2.93e-67 - - - S - - - MazG nucleotide pyrophosphohydrolase domain
MEDPMIKA_00609 2.28e-209 - - - G - - - Domain of unknown function (DUF4091)
MEDPMIKA_00610 1.79e-229 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MEDPMIKA_00611 1.39e-247 manC 2.7.7.13 - M ko:K00971 ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
MEDPMIKA_00612 1.09e-130 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEDPMIKA_00613 0.0 - - - H - - - Putative porin
MEDPMIKA_00614 4.6e-136 mltF - - M ko:K18691 - ko00000,ko01000,ko01011 Transglycosylase SLT domain
MEDPMIKA_00615 5.27e-10 - - - K ko:K03088 - ko00000,ko03021 Sigma-70, region 4
MEDPMIKA_00616 8.04e-198 - - - S - - - Calcineurin-like phosphoesterase
MEDPMIKA_00617 2.19e-07 - - - L - - - Endonuclease Exonuclease phosphatase
MEDPMIKA_00618 0.000183 - - - S - - - Concanavalin A-like lectin/glucanases superfamily
MEDPMIKA_00619 4.71e-214 - - - P ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_00620 0.0 - - - P - - - PFAM TonB-dependent Receptor Plug
MEDPMIKA_00621 9.96e-62 - - - PT - - - Sigma factor regulatory protein, FecR PupR family
MEDPMIKA_00622 0.0 - - - S - - - Putative carbohydrate metabolism domain
MEDPMIKA_00623 3.63e-151 - - - NU - - - Psort location
MEDPMIKA_00624 1.61e-163 - - - NU - - - Tfp pilus assembly protein FimV
MEDPMIKA_00625 1.96e-219 - - - S - - - Domain of unknown function (DUF4493)
MEDPMIKA_00626 4.32e-177 - - - S - - - Domain of unknown function (DUF4493)
MEDPMIKA_00627 1.21e-89 - - - S - - - Domain of unknown function (DUF4493)
MEDPMIKA_00629 0.0 pop - - EU - - - X-Pro dipeptidyl-peptidase (S15 family)
MEDPMIKA_00630 1.51e-114 - - - F - - - Belongs to the Nudix hydrolase family
MEDPMIKA_00631 5.05e-106 - - - KT ko:K02477,ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
MEDPMIKA_00632 7.72e-38 - - - - - - - -
MEDPMIKA_00633 6.59e-257 - - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 MutS domain V
MEDPMIKA_00634 6.51e-86 - - - S - - - Polyketide cyclase
MEDPMIKA_00635 6.96e-128 - - - E - - - Transglutaminase-like superfamily
MEDPMIKA_00636 1.7e-87 yjeE - - S ko:K06925 - ko00000,ko03016 Threonylcarbamoyl adenosine biosynthesis protein TsaE
MEDPMIKA_00637 0.0 - - - KT - - - PglZ domain
MEDPMIKA_00638 5.6e-63 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MEDPMIKA_00639 7.24e-29 - - - CO - - - Thioredoxin domain
MEDPMIKA_00640 9.93e-50 - - - - - - - -
MEDPMIKA_00641 4.78e-139 - - - CO - - - Cytochrome C biogenesis protein transmembrane region
MEDPMIKA_00642 5.06e-198 - - - S ko:K07089 - ko00000 Predicted permease
MEDPMIKA_00643 4.99e-53 hupA - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
MEDPMIKA_00644 0.000144 - - - - - - - -
MEDPMIKA_00645 0.0 rng - - J ko:K08301 - ko00000,ko01000,ko03009,ko03019 Ribonuclease E/G family
MEDPMIKA_00646 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MEDPMIKA_00647 4.3e-152 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MEDPMIKA_00648 2.31e-282 - - - I - - - Psort location OuterMembrane, score
MEDPMIKA_00649 1.52e-277 - - - S - - - Tetratricopeptide repeat protein
MEDPMIKA_00650 1.52e-112 - - - S - - - Lipopolysaccharide-assembly, LptC-related
MEDPMIKA_00651 2.63e-270 tlyC - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
MEDPMIKA_00652 0.0 ppiD 5.2.1.8 - O ko:K01802,ko:K03770 - ko00000,ko01000,ko03110 SurA N-terminal domain
MEDPMIKA_00653 1.91e-245 yqhD - - C ko:K08325 ko00640,map00640 ko00000,ko00001,ko01000 alcohol dehydrogenase
MEDPMIKA_00655 0.0 mutB 5.4.99.2 - I ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 B12 binding domain
MEDPMIKA_00656 0.0 mutA 5.4.99.2 - I ko:K01847 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Methylmalonyl-CoA mutase
MEDPMIKA_00657 0.0 glnA 6.3.1.2 - S ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 Glutamine synthetase, catalytic domain
MEDPMIKA_00658 1.26e-34 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MEDPMIKA_00659 1.61e-216 comEA - - L - - - Helix-hairpin-helix motif
MEDPMIKA_00660 1.97e-169 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MEDPMIKA_00661 4.45e-156 - - - G - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_00662 4.61e-71 - - - K - - - Transcriptional regulator, BlaI MecI CopY family
MEDPMIKA_00663 1.03e-193 - - - KT - - - BlaR1 peptidase M56
MEDPMIKA_00664 0.0 - - - M - - - Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MEDPMIKA_00665 7.21e-81 yocK - - T - - - Prokaryotic dksA/traR C4-type zinc finger
MEDPMIKA_00666 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MEDPMIKA_00667 2.3e-107 - - - T - - - PAS domain S-box protein
MEDPMIKA_00668 3.14e-102 maa 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Bacterial transferase hexapeptide
MEDPMIKA_00669 0.0 msbA - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter, ATP-binding protein
MEDPMIKA_00670 2.82e-105 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEDPMIKA_00671 6.44e-158 - - - CO - - - AhpC/TSA family
MEDPMIKA_00672 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MEDPMIKA_00673 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MEDPMIKA_00674 1.42e-165 kdsB 2.7.7.38 - M ko:K00979 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MEDPMIKA_00675 6.22e-163 kdsA 2.5.1.55 - M ko:K01627 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the KdsA family
MEDPMIKA_00676 1.91e-213 kdsD 5.3.1.13 - M ko:K06041 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the SIS family. GutQ KpsF subfamily
MEDPMIKA_00677 5.19e-68 - - - KT - - - PAS domain
MEDPMIKA_00678 0.0 clcB - - P ko:K03281 - ko00000 Voltage gated chloride channel
MEDPMIKA_00679 2.54e-248 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MEDPMIKA_00680 3.29e-203 oxyR - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain protein
MEDPMIKA_00682 9.53e-305 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_00683 9.68e-83 - - - S - - - COG3943, virulence protein
MEDPMIKA_00684 3.41e-65 - - - L - - - Helix-turn-helix domain
MEDPMIKA_00685 1.5e-54 - - - - - - - -
MEDPMIKA_00686 1.69e-73 - - - L - - - Helix-turn-helix domain
MEDPMIKA_00687 3.86e-78 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
MEDPMIKA_00688 0.0 - - - S - - - Protein of unknown function (DUF4099)
MEDPMIKA_00689 0.0 - 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase
MEDPMIKA_00690 4.73e-102 - - - S - - - Domain of unknown function (DUF1896)
MEDPMIKA_00691 0.0 - - - L - - - Helicase C-terminal domain protein
MEDPMIKA_00692 3.44e-92 - - - S - - - SnoaL-like polyketide cyclase
MEDPMIKA_00693 1.78e-196 - - - K - - - Acetyltransferase (GNAT) domain
MEDPMIKA_00694 0.0 tetP - - J ko:K18220 - br01600,ko00000,ko01504 Elongation Factor G, domain II
MEDPMIKA_00695 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEDPMIKA_00696 0.0 zraR - - T ko:K07713 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Bacterial regulatory protein, Fis family
MEDPMIKA_00697 1.35e-97 - - - H - - - RibD C-terminal domain
MEDPMIKA_00698 5.47e-33 rteC - - S - - - RteC protein
MEDPMIKA_00699 2.52e-78 rteC - - S - - - RteC protein
MEDPMIKA_00700 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
MEDPMIKA_00701 0.0 - - - L - - - Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MEDPMIKA_00702 1.73e-46 - - - S - - - Domain of unknown function, B. Theta Gene description (DUF3873)
MEDPMIKA_00703 1.23e-100 infC - - J ko:K02520 - ko00000,ko03012,ko03029 translation initiation factor IF-3
MEDPMIKA_00704 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MEDPMIKA_00705 1.27e-235 pdxA 1.1.1.262 - H ko:K00097 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the PdxA family
MEDPMIKA_00707 2.61e-144 aviRb - - J ko:K03437 - ko00000,ko03016 SpoU rRNA Methylase family
MEDPMIKA_00708 5.46e-206 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MEDPMIKA_00710 5.46e-206 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MEDPMIKA_00711 5.37e-118 - - - S - - - protein trimerization
MEDPMIKA_00712 3.68e-177 - - - S - - - von Willebrand factor (vWF) type A domain
MEDPMIKA_00713 0.0 - - - G - - - Domain of unknown function (DUF4954)
MEDPMIKA_00714 3.12e-200 - - - KLT - - - WG containing repeat
MEDPMIKA_00715 1.48e-110 slyD 5.2.1.8 - G ko:K03775 - ko00000,ko01000,ko03110 FKBP-type peptidyl-prolyl cis-trans isomerase
MEDPMIKA_00716 0.0 gcvP 1.4.4.2 - E ko:K00281,ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the GcvP family
MEDPMIKA_00717 0.0 udk2 2.7.1.48 - FJ ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Phosphoribulokinase / Uridine kinase family
MEDPMIKA_00718 2.6e-299 yfkN_2 3.1.3.5, 3.6.1.45 - F ko:K01081,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Ser Thr phosphatase family protein
MEDPMIKA_00719 0.0 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MEDPMIKA_00721 1.69e-188 - - - EG - - - COG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MEDPMIKA_00722 2.08e-81 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MEDPMIKA_00723 1.07e-57 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MEDPMIKA_00724 3.08e-74 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MEDPMIKA_00725 4.43e-122 - - - - - - - -
MEDPMIKA_00726 1.26e-225 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MEDPMIKA_00727 1.76e-117 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MEDPMIKA_00728 6.37e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MEDPMIKA_00730 3.92e-151 - 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MEDPMIKA_00731 2.01e-194 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEDPMIKA_00733 1.19e-220 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MEDPMIKA_00736 9.42e-51 - - - N - - - Putative binding domain, N-terminal
MEDPMIKA_00739 2.77e-250 - - - S - - - VirE N-terminal domain
MEDPMIKA_00740 2.75e-79 - - - - - - - -
MEDPMIKA_00741 2.99e-71 - - - L - - - DNA binding domain, excisionase family
MEDPMIKA_00742 9.14e-127 - - - L - - - transposition, DNA-mediated
MEDPMIKA_00743 1.46e-301 - - - L - - - Arm DNA-binding domain
MEDPMIKA_00744 2.49e-267 - - - S - - - ATPase (AAA superfamily)
MEDPMIKA_00745 8.18e-143 - - - S - - - cog cog4185
MEDPMIKA_00747 4.34e-173 - - - L - - - COG NOG27661 non supervised orthologous group
MEDPMIKA_00748 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Beta galactosidase small chain
MEDPMIKA_00749 0.0 eam 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 KamA family
MEDPMIKA_00750 4.03e-153 - - - S ko:K06911 - ko00000 Belongs to the pirin family
MEDPMIKA_00751 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MEDPMIKA_00752 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
MEDPMIKA_00753 6.33e-273 queA 2.4.99.17 - H ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MEDPMIKA_00754 1.93e-111 - - - M - - - Outer membrane protein beta-barrel domain
MEDPMIKA_00755 2.46e-91 - - - K - - - Peptidase S24-like
MEDPMIKA_00761 9.79e-229 - - - L - - - Transposase and inactivated derivatives
MEDPMIKA_00762 1.47e-86 - 3.6.1.3 - S ko:K07132 - ko00000,ko01000 AAA domain
MEDPMIKA_00763 2.71e-76 - - - O - - - ATP-dependent serine protease
MEDPMIKA_00764 4.18e-16 - - - - - - - -
MEDPMIKA_00765 1.21e-21 - - - S - - - Domain of unknown function (DUF4406)
MEDPMIKA_00766 2.51e-18 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_00771 2.41e-68 - - - S - - - Protein of unknown function (DUF3164)
MEDPMIKA_00773 5.02e-39 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_00774 4.83e-37 - - - - - - - -
MEDPMIKA_00775 2.09e-63 - - - S - - - Phage virion morphogenesis
MEDPMIKA_00776 3.87e-53 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_00777 3.76e-136 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_00778 3.3e-59 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_00779 4.13e-220 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_00780 1.49e-46 - - - - - - - -
MEDPMIKA_00781 8.28e-79 - - - OU - - - Psort location Cytoplasmic, score
MEDPMIKA_00782 2.14e-112 - - - - - - - -
MEDPMIKA_00784 9.31e-71 - - - NU ko:K02395 - ko00000,ko02035 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MEDPMIKA_00786 1.13e-31 - - - - - - - -
MEDPMIKA_00787 9.27e-63 - - - - - - - -
MEDPMIKA_00788 8.35e-14 - - - - - - - -
MEDPMIKA_00789 0.0 - - - D - - - Psort location OuterMembrane, score
MEDPMIKA_00790 5.22e-56 - - - - - - - -
MEDPMIKA_00792 0.0 - - - S - - - Phage minor structural protein
MEDPMIKA_00794 0.0 - - - - - - - -
MEDPMIKA_00795 3.13e-213 - - - L - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_00796 2.86e-67 - - - - - - - -
MEDPMIKA_00797 5.65e-163 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 D12 class N6 adenine-specific DNA methyltransferase
MEDPMIKA_00798 4.81e-94 - - - M - - - Outer membrane protein beta-barrel domain
MEDPMIKA_00799 6.87e-246 - - - P - - - Psort location CytoplasmicMembrane, score 10.00
MEDPMIKA_00800 1.78e-302 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MEDPMIKA_00802 1.02e-47 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MEDPMIKA_00803 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MEDPMIKA_00804 1.14e-201 - - - EG - - - EamA-like transporter family
MEDPMIKA_00805 2.95e-127 - - - S - - - COG NOG23385 non supervised orthologous group
MEDPMIKA_00806 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MEDPMIKA_00807 9.6e-257 coaBC 4.1.1.36, 6.3.2.5 - H ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MEDPMIKA_00808 6.59e-65 rpoZ - - K - - - RNA polymerase Rpb6
MEDPMIKA_00809 3.61e-164 yfiO - - S ko:K05807 - ko00000,ko02000 outer membrane assembly lipoprotein YfiO
MEDPMIKA_00811 1.25e-276 - - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEDPMIKA_00812 8.9e-95 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEDPMIKA_00814 0.0 - - - P ko:K16089 - ko00000,ko02000 Outer membrane receptor for ferrienterochelin and colicins
MEDPMIKA_00815 1.2e-212 mdh 1.1.1.37 - C ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible oxidation of malate to oxaloacetate
MEDPMIKA_00816 9.89e-83 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MEDPMIKA_00818 1.1e-133 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Biotin/lipoate A/B protein ligase family
MEDPMIKA_00819 7.71e-158 dapD 2.3.1.117 - E ko:K00674 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transferase hexapeptide repeat family
MEDPMIKA_00820 0.0 pep 3.4.21.26 - E ko:K01322 ko04614,map04614 ko00000,ko00001,ko01000,ko01002 Peptidase, S9A B C family, catalytic domain protein
MEDPMIKA_00821 9.56e-286 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MEDPMIKA_00822 4.5e-241 - - - P - - - Protein of unknown function (DUF4435)
MEDPMIKA_00823 3.59e-69 - - - J ko:K03113 ko03013,map03013 ko00000,ko00001,ko03012 Translation initiation factor SUI1
MEDPMIKA_00824 0.0 - - - U - - - Involved in the tonB-independent uptake of proteins
MEDPMIKA_00825 0.0 mrcA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Transglycosylase
MEDPMIKA_00826 4.03e-12 - - - S - - - regulation of response to stimulus
MEDPMIKA_00827 5.98e-110 - - - S - - - Putative zinc-binding metallo-peptidase
MEDPMIKA_00828 7.28e-133 - - - G ko:K21572 - ko00000,ko02000 Starch-binding associating with outer membrane
MEDPMIKA_00829 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_00830 1.63e-196 - - - T - - - Response regulator receiver domain protein
MEDPMIKA_00831 2.7e-213 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MEDPMIKA_00832 5.85e-194 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_00833 6.27e-308 - 3.1.1.53 - S ko:K05970 - ko00000,ko01000 Carbohydrate esterase, sialic acid-specific acetylesterase
MEDPMIKA_00834 4.17e-314 tnaA 4.1.99.1 - E ko:K01667 ko00380,map00380 ko00000,ko00001,ko01000 Beta-eliminating lyase
MEDPMIKA_00835 1.08e-24 rubR - - C - - - rubredoxin
MEDPMIKA_00836 3.92e-116 - 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MEDPMIKA_00838 1.64e-70 nuoA 1.6.5.3 - C ko:K00330 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MEDPMIKA_00839 2.31e-135 nuoB 1.6.5.3 - C ko:K00331 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MEDPMIKA_00840 0.0 nuoC 1.6.5.3 - C ko:K00333,ko:K13378 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MEDPMIKA_00842 6.28e-249 nuoH 1.6.5.3 - C ko:K00337 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MEDPMIKA_00843 8.7e-78 nuoI 1.6.5.3 - C ko:K00338 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MEDPMIKA_00844 2.3e-100 ndhG 1.6.5.3 - C ko:K00339 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the complex I subunit 6 family
MEDPMIKA_00845 2.21e-57 nuoK 1.6.5.3 - C ko:K00340 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MEDPMIKA_00846 0.0 nuoL 1.6.5.3 - CP ko:K00341 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Proton-translocating NADH-quinone oxidoreductase, chain L
MEDPMIKA_00847 0.0 nuoM 1.6.5.3 - C ko:K00342 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 proton-translocating NADH-quinone oxidoreductase, chain M
MEDPMIKA_00848 4.17e-281 nuoN 1.6.5.3 - C ko:K00343 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MEDPMIKA_00849 1.02e-81 ogt 2.1.1.63 - L ko:K00567,ko:K10778 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MEDPMIKA_00850 0.0 dpp 3.4.14.5 - EU ko:K01278 ko04974,map04974 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 Dipeptidyl peptidase IV (DPP IV) N-terminal region
MEDPMIKA_00851 1.15e-138 - - - - - - - -
MEDPMIKA_00852 7.83e-206 lytG - - MNU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MEDPMIKA_00853 5.72e-137 - - - M - - - Protein of unknown function (DUF4254)
MEDPMIKA_00854 2.93e-195 - - GT9 M ko:K02843 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 heptosyltransferase
MEDPMIKA_00855 4.39e-75 - - - G - - - Domain of unknown function (DUF4886)
MEDPMIKA_00856 5.57e-30 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor
MEDPMIKA_00858 2.06e-21 - - - PT - - - Sigma factor regulatory protein, FecR PupR family
MEDPMIKA_00859 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_00860 1.26e-162 - - - S ko:K21572 - ko00000,ko02000 Pfam:SusD
MEDPMIKA_00861 3.72e-58 - - - G - - - Phosphodiester glycosidase
MEDPMIKA_00862 2.17e-50 - - - U - - - Parallel beta-helix repeats
MEDPMIKA_00863 2.31e-103 - - - G - - - Xylose isomerase-like TIM barrel
MEDPMIKA_00864 1.71e-151 - - - G - - - Phosphodiester glycosidase
MEDPMIKA_00865 2.91e-97 - - - S - - - Lipocalin-like
MEDPMIKA_00866 4.36e-314 gltA 1.3.1.1, 1.4.1.13, 1.4.1.14 - C ko:K00266,ko:K17722 ko00240,ko00250,ko00410,ko00770,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00410,map00770,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MEDPMIKA_00867 6.13e-201 gltD 1.18.1.2, 1.19.1.1 - C ko:K00528 - ko00000,ko01000 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
MEDPMIKA_00868 5.39e-200 - - - S - - - Protein of unknown function (DUF1573)
MEDPMIKA_00869 3.5e-68 - - - U - - - Relaxase/Mobilisation nuclease domain
MEDPMIKA_00870 1.81e-113 - - - U - - - Relaxase/Mobilisation nuclease domain
MEDPMIKA_00871 1.13e-80 - - - - - - - -
MEDPMIKA_00872 2.79e-91 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MEDPMIKA_00873 2.26e-259 ce 5.1.3.8 - G ko:K01787 ko00520,map00520 ko00000,ko00001,ko01000 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
MEDPMIKA_00874 5.33e-272 araE - - P ko:K02100 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MEDPMIKA_00875 1.32e-212 - - - S - - - Domain of unknown function (DUF5109)
MEDPMIKA_00876 4.55e-191 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
MEDPMIKA_00877 0.0 susB 3.2.1.20, 3.2.1.3 GH31,GH97 G ko:K01187,ko:K21574 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 alpha-glucosidase
MEDPMIKA_00878 5.41e-301 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Beta galactosidase small chain
MEDPMIKA_00879 2.77e-35 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
MEDPMIKA_00881 2.01e-71 - - - C - - - Domain of unknown function (DUF4855)
MEDPMIKA_00882 1.23e-198 - - - G - - - Phosphodiester glycosidase
MEDPMIKA_00884 2.21e-58 - - - C - - - Domain of unknown function (DUF4855)
MEDPMIKA_00886 1.79e-233 - - - P ko:K21572 - ko00000,ko02000 non supervised orthologous group
MEDPMIKA_00887 0.0 - - - H - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_00888 7.32e-110 nagC 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
MEDPMIKA_00889 3.14e-91 - - - K - - - helix_turn_helix, arabinose operon control protein
MEDPMIKA_00890 5.82e-35 - - - - - - - -
MEDPMIKA_00891 9.92e-169 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MEDPMIKA_00892 4e-158 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the DapB family
MEDPMIKA_00893 1.92e-301 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase I
MEDPMIKA_00894 2.17e-121 yigZ - - S - - - Uncharacterized protein family UPF0029
MEDPMIKA_00895 0.0 uvrA1 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MEDPMIKA_00896 3.76e-255 - - - S - - - Insulinase (Peptidase family M16)
MEDPMIKA_00897 5.08e-129 - - - E - - - DJ-1 PfpI family protein
MEDPMIKA_00898 8.89e-134 mdmC 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
MEDPMIKA_00899 2.96e-66 ypjD - - J - - - MazG nucleotide pyrophosphohydrolase domain protein
MEDPMIKA_00900 4.75e-22 - - - KT - - - BlaR1 peptidase M56
MEDPMIKA_00901 4.82e-109 - - - KT - - - BlaR1 peptidase M56
MEDPMIKA_00902 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II
MEDPMIKA_00903 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MEDPMIKA_00904 1.22e-34 - - - CO - - - Domain of unknown function (DUF4369)
MEDPMIKA_00905 3.08e-85 - - - S ko:K06889 - ko00000 Serine aminopeptidase, S33
MEDPMIKA_00906 4.85e-197 - - - K - - - HTH domain protein
MEDPMIKA_00907 1.71e-89 - - - G - - - Cupin domain
MEDPMIKA_00909 2.41e-108 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Redoxin
MEDPMIKA_00910 2.19e-225 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MEDPMIKA_00911 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MEDPMIKA_00915 6.88e-80 hinT - - FG ko:K02503 - ko00000,ko04147 HIT domain
MEDPMIKA_00916 1.13e-53 - - - K - - - Helix-turn-helix XRE-family like proteins
MEDPMIKA_00917 6.03e-135 - - - P ko:K21990,ko:K21993 - ko00000,ko02000 Formate/nitrite transporter
MEDPMIKA_00918 1.96e-141 mntA - - P ko:K09815,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Zinc-uptake complex component A periplasmic
MEDPMIKA_00919 2.94e-167 znuC - - P ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEDPMIKA_00920 4.27e-52 - - - S - - - COG NOG23371 non supervised orthologous group
MEDPMIKA_00921 1.06e-117 - 2.7.11.1 - - ko:K14949 ko05152,map05152 ko00000,ko00001,ko01000,ko01001 -
MEDPMIKA_00922 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl tRNA synthetase N terminal dom
MEDPMIKA_00923 2.23e-257 corC_1 - - P ko:K03699 - ko00000,ko02042 Psort location CytoplasmicMembrane, score
MEDPMIKA_00924 1.1e-233 dus - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEDPMIKA_00926 0.0 - - - G - - - Belongs to the glycosyl hydrolase 2 family
MEDPMIKA_00927 7.37e-107 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
MEDPMIKA_00928 5.92e-82 - - - S - - - COG NOG14473 non supervised orthologous group
MEDPMIKA_00930 1.12e-180 mscS - - M ko:K03442 - ko00000,ko02000 Small-conductance mechanosensitive channel
MEDPMIKA_00931 1.07e-277 serB 3.1.3.3 - ET ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 phosphoserine phosphatase
MEDPMIKA_00932 1.88e-133 - - - S - - - PFAM nucleic acid binding, OB-fold, tRNA
MEDPMIKA_00933 2.02e-121 - - - S - - - PFAM nucleic acid binding, OB-fold, tRNA
MEDPMIKA_00934 1.15e-238 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MEDPMIKA_00935 1.17e-230 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MEDPMIKA_00936 0.0 leuA_1 2.3.1.182 - E ko:K09011 ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 LeuA allosteric (dimerisation) domain
MEDPMIKA_00937 7.62e-125 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MEDPMIKA_00938 4.54e-316 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MEDPMIKA_00939 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MEDPMIKA_00940 7.89e-248 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
MEDPMIKA_00941 0.0 - - - P - - - Psort location OuterMembrane, score
MEDPMIKA_00942 0.0 pepD_1 - - E ko:K01270 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Peptidase family M20/M25/M40
MEDPMIKA_00943 2.58e-100 ispF 4.6.1.12 - H ko:K01770 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MEDPMIKA_00944 1.44e-59 - - - C - - - Sulfatase-modifying factor enzyme 1
MEDPMIKA_00947 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MEDPMIKA_00949 5.44e-145 yafV 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
MEDPMIKA_00950 0.0 - - - S ko:K06978 - ko00000 Hydrolase CocE NonD family
MEDPMIKA_00951 5.77e-184 yitL - - S ko:K00243 - ko00000 S1 domain
MEDPMIKA_00952 2.03e-154 - - - Q - - - Methyltransferase domain
MEDPMIKA_00953 0.0 - - - G - - - Glycogen debranching enzyme
MEDPMIKA_00954 1.53e-45 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_00955 5.49e-108 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
MEDPMIKA_00957 1.19e-276 yhiN - - S ko:K07007 - ko00000 HI0933-like protein
MEDPMIKA_00959 1.49e-203 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 NusB family
MEDPMIKA_00960 1.01e-74 - - - S - - - Protein of unknown function (DUF1573)
MEDPMIKA_00961 8.82e-68 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
MEDPMIKA_00962 2.9e-63 nrdG 1.97.1.4 - C ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEDPMIKA_00963 0.0 nrdD 1.1.98.6 - FK ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MEDPMIKA_00964 3.73e-40 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_00965 2.82e-37 - - - S - - - Transglycosylase associated protein
MEDPMIKA_00967 8.37e-271 nhaD - - P - - - Citrate transporter
MEDPMIKA_00968 6.49e-46 - - - O - - - Psort location Extracellular, score
MEDPMIKA_00969 1.72e-34 - - - O - - - Peptidase, S8 S53 family
MEDPMIKA_00971 1.15e-67 - - - S - - - Thioesterase superfamily
MEDPMIKA_00972 1.35e-121 - - - S - - - Domain of unknown function (DUF4294)
MEDPMIKA_00974 2.68e-293 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MEDPMIKA_00978 1.23e-195 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MEDPMIKA_00979 2.94e-198 - - - S - - - Tetratricopeptide repeat
MEDPMIKA_00980 4.4e-309 - - - G - - - Major Facilitator Superfamily
MEDPMIKA_00981 1.2e-61 - - - S - - - GtrA-like protein
MEDPMIKA_00982 7.79e-191 - - - G - - - polysaccharide deacetylase
MEDPMIKA_00983 0.0 - - - M - - - Psort location CytoplasmicMembrane, score 10.00
MEDPMIKA_00984 4.21e-255 - - - M - - - Glycosyl transferases group 1
MEDPMIKA_00985 1.17e-112 - 1.16.3.1 - P ko:K03594 ko00860,map00860 ko00000,ko00001,ko01000 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex
MEDPMIKA_00986 2.23e-152 - 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MEDPMIKA_00987 2.89e-92 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
MEDPMIKA_00988 9.8e-133 - - - S - - - Protein of unknown function (DUF2975)
MEDPMIKA_00989 4.31e-35 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MEDPMIKA_00990 0.0 - - - S ko:K07263 - ko00000,ko01000,ko01002 Belongs to the peptidase M16 family
MEDPMIKA_00991 0.0 - - - M - - - Sulfatase
MEDPMIKA_00992 1.28e-197 - - - - - - - -
MEDPMIKA_00993 0.0 - - - P - - - Psort location OuterMembrane, score
MEDPMIKA_00994 5.47e-236 - - - S - - - Endonuclease exonuclease phosphatase family
MEDPMIKA_00995 2.01e-162 - - - F ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 DNA RNA non-specific endonuclease
MEDPMIKA_00996 2.49e-45 - - - - - - - -
MEDPMIKA_00997 8.48e-82 - - - S - - - Domain of unknown function (DUF4293)
MEDPMIKA_00998 3.48e-210 arnC - - M - - - Glycosyltransferase like family 2
MEDPMIKA_01000 4.81e-124 yciO - - J - - - Belongs to the SUA5 family
MEDPMIKA_01001 4.85e-200 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MEDPMIKA_01002 6.11e-206 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FMN-dependent dehydrogenase
MEDPMIKA_01003 2.23e-174 - - - S - - - NYN domain
MEDPMIKA_01004 5.57e-55 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
MEDPMIKA_01005 1.64e-74 - - - - - - - -
MEDPMIKA_01006 0.0 - - - L - - - Helicase conserved C-terminal domain
MEDPMIKA_01007 0.0 - - - KL - - - DNA restriction-modification system
MEDPMIKA_01008 1.74e-32 - - - L - - - DNA restriction-modification system
MEDPMIKA_01009 9.1e-87 - - - S - - - Domain of unknown function (DUF1896)
MEDPMIKA_01010 1.46e-200 - - - S - - - Protein of unknown function (DUF3945)
MEDPMIKA_01012 5.28e-14 - - - L - - - Pfam Transposase DDE domain
MEDPMIKA_01013 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEDPMIKA_01015 6.52e-65 - - - - - - - -
MEDPMIKA_01016 1.13e-05 - - - P - - - PFAM TonB-dependent Receptor Plug
MEDPMIKA_01017 2.93e-24 - - - P - - - Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MEDPMIKA_01018 6.44e-271 - - - MU - - - Outer membrane efflux protein
MEDPMIKA_01019 0.0 - - - V - - - Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MEDPMIKA_01020 1.09e-183 - - - M - - - Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MEDPMIKA_01021 2.06e-159 - - - K - - - transcriptional regulator (AraC family)
MEDPMIKA_01022 5.15e-240 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MEDPMIKA_01023 1.89e-169 - - - S - - - Endonuclease/Exonuclease/phosphatase family
MEDPMIKA_01024 9.06e-170 - - - EG - - - Psort location CytoplasmicMembrane, score 10.00
MEDPMIKA_01025 2.27e-142 - - - M - - - Glycosyltransferase, group 2 family protein
MEDPMIKA_01026 4.42e-175 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEDPMIKA_01027 4.37e-245 hutI 3.5.2.7 - F ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
MEDPMIKA_01028 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
MEDPMIKA_01029 0.0 hutU 4.2.1.49 - H ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MEDPMIKA_01030 0.0 ftcD 2.1.2.5, 4.3.1.4 - E ko:K00603,ko:K13990 ko00340,ko00670,ko01100,map00340,map00670,map01100 ko00000,ko00001,ko01000,ko03036,ko04147 Formiminotransferase domain, N-terminal subdomain
MEDPMIKA_01031 0.0 - - - H ko:K02014 - ko00000,ko02000 TonB-dependent receptor
MEDPMIKA_01032 9.16e-230 - - - E - - - Pectic acid lyase
MEDPMIKA_01033 1.8e-289 - 2.5.1.76 - E ko:K15527 - ko00000,ko01000 Pyridoxal-phosphate dependent enzyme
MEDPMIKA_01034 1.73e-268 nspC 4.1.1.96 - E ko:K13747 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 carboxynorspermidine decarboxylase
MEDPMIKA_01035 2.59e-299 LYS1 1.5.1.7 - E ko:K00290 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Saccharopine dehydrogenase
MEDPMIKA_01037 6.21e-244 - - - V - - - Restriction endonuclease
MEDPMIKA_01038 4.05e-92 - 1.14.13.22 - S ko:K03379 ko00930,ko01120,ko01220,map00930,map01120,map01220 ko00000,ko00001,ko01000 polysaccharide biosynthetic process
MEDPMIKA_01039 7.92e-60 - - - G - - - COG NOG13250 non supervised orthologous group
MEDPMIKA_01040 9.21e-189 rfbA 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MEDPMIKA_01041 2.37e-98 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MEDPMIKA_01042 8.73e-149 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MEDPMIKA_01043 5.74e-242 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MEDPMIKA_01044 4.21e-100 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MEDPMIKA_01045 0.0 - - - M - - - CarboxypepD_reg-like domain
MEDPMIKA_01046 4.6e-130 - - - S - - - HAD-hyrolase-like
MEDPMIKA_01047 3.52e-36 - - - P ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MEDPMIKA_01048 9.65e-79 - - - S ko:K09922 - ko00000 Putative member of DMT superfamily (DUF486)
MEDPMIKA_01049 1.68e-151 vat_2 - - S ko:K18234 - ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
MEDPMIKA_01050 6.85e-263 fsr - - EGP ko:K08223 - ko00000,ko02000 Transporter, major facilitator family protein
MEDPMIKA_01051 4.45e-85 - - - L - - - HNH endonuclease
MEDPMIKA_01052 0.0 - 3.6.4.12 - L ko:K03658 - ko00000,ko01000,ko03400 DNA helicase
MEDPMIKA_01054 7.4e-138 - - - S - - - Protein of unknown function (DUF2813)
MEDPMIKA_01055 2.79e-09 - - - S - - - AAA ATPase domain
MEDPMIKA_01056 3.19e-55 - - - K - - - Helix-turn-helix domain
MEDPMIKA_01057 0.0 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
MEDPMIKA_01058 8.74e-261 - - - L - - - Domain of unknown function (DUF1848)
MEDPMIKA_01059 0.0 - - - - - - - -
MEDPMIKA_01060 3.25e-252 - - - L - - - Viral (Superfamily 1) RNA helicase
MEDPMIKA_01061 0.0 - - - - - - - -
MEDPMIKA_01062 5.84e-275 - - - L - - - Plasmid recombination enzyme
MEDPMIKA_01063 4.92e-145 - - - L - - - COG NOG08810 non supervised orthologous group
MEDPMIKA_01064 3.15e-295 - - - S - - - COG NOG11635 non supervised orthologous group
MEDPMIKA_01065 1.98e-67 - - - L - - - Helix-turn-helix domain
MEDPMIKA_01066 6.47e-186 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_01067 6.3e-292 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_01068 1.07e-298 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_01069 8.7e-27 - - - - - - - -
MEDPMIKA_01070 3.96e-173 - - - S - - - Plasmid recombination enzyme
MEDPMIKA_01071 4.98e-146 - - - L - - - Toprim-like
MEDPMIKA_01072 1.25e-211 - - - T - - - AAA domain
MEDPMIKA_01073 1.9e-46 - - - K - - - Helix-turn-helix domain
MEDPMIKA_01074 5.35e-121 - - - - - - - -
MEDPMIKA_01075 2.68e-242 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_01076 7.65e-182 - - - S ko:K03453 - ko00000 Sodium bile acid symporter family
MEDPMIKA_01077 5.7e-89 - - - S ko:K09117 - ko00000 YqeY-like protein
MEDPMIKA_01078 4.5e-105 - - - S - - - Acetyltransferase (GNAT) domain
MEDPMIKA_01079 0.0 - - - M - - - Fibronectin type 3 domain
MEDPMIKA_01080 1.53e-303 - - - E - - - Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MEDPMIKA_01081 2.95e-90 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MEDPMIKA_01082 0.0 hppA 3.6.1.1 - C ko:K15987 ko00190,map00190 ko00000,ko00001,ko01000 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
MEDPMIKA_01083 1.65e-203 yhiM - - S - - - Psort location CytoplasmicMembrane, score 10.00
MEDPMIKA_01084 6.24e-128 - - - S ko:K07025 - ko00000 IA, variant 3
MEDPMIKA_01085 0.0 - - - P - - - Carboxypeptidase regulatory-like domain
MEDPMIKA_01086 1.75e-203 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
MEDPMIKA_01087 0.0 - 4.1.1.3, 6.4.1.1 - C ko:K01571,ko:K01960 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko02000 Conserved carboxylase domain
MEDPMIKA_01088 1.51e-305 - 1.2.5.1, 2.2.1.6 - E ko:K00156,ko:K01652 ko00290,ko00620,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
MEDPMIKA_01089 4.65e-93 - 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEDPMIKA_01091 7.15e-132 - - - S ko:K10716 - ko00000,ko02000 Ion channel
MEDPMIKA_01092 4.07e-295 - - - G - - - Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MEDPMIKA_01093 2.7e-165 - - - - - - - -
MEDPMIKA_01095 2.31e-308 - - - - - - - -
MEDPMIKA_01096 1.28e-191 - 3.1.11.2 - S ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease/Exonuclease/phosphatase family
MEDPMIKA_01097 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_01098 3.71e-172 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_01099 0.0 - - - Q ko:K21572 - ko00000,ko02000 pyridine nucleotide-disulphide oxidoreductase
MEDPMIKA_01100 0.0 - - - S - - - Putative binding domain, N-terminal
MEDPMIKA_01101 0.0 - - - - - - - -
MEDPMIKA_01102 0.0 - - - G - - - Glycosyl hydrolase family 20, catalytic domain
MEDPMIKA_01104 3.28e-296 nqrF 1.6.5.8 - C ko:K00351 - ko00000,ko01000 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway
MEDPMIKA_01105 1.61e-120 nqrE 1.6.5.8 - C ko:K00350 - ko00000,ko01000 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MEDPMIKA_01106 5.64e-144 nqrD 1.6.5.8 - C ko:K00349 - ko00000,ko01000 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MEDPMIKA_01107 1.15e-179 nqrC 1.6.5.8 - C ko:K00348 - ko00000,ko01000 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MEDPMIKA_01108 1.58e-243 nqrB 1.6.5.8 - C ko:K00347 - ko00000,ko01000 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MEDPMIKA_01109 3.16e-312 nqrA 1.6.5.8 - C ko:K00346 - ko00000,ko01000 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MEDPMIKA_01110 2.16e-107 - - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MEDPMIKA_01111 2.76e-158 hypB - - H ko:K22132 - ko00000,ko03016 ThiF family
MEDPMIKA_01112 8.14e-195 hprA 1.1.1.29 - CH ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEDPMIKA_01113 4e-21 - - - M - - - Glycosyltransferase like family 2
MEDPMIKA_01114 3.05e-97 proX - - S ko:K19055 - ko00000,ko01000,ko03016 YbaK proline--tRNA ligase associated domain protein
MEDPMIKA_01115 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEDPMIKA_01116 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MEDPMIKA_01117 8.72e-217 - - - M - - - Peptidase family M23
MEDPMIKA_01118 5.9e-194 - - - M - - - Peptidase family M23
MEDPMIKA_01119 4.29e-113 - - - S - - - Haloacid dehalogenase-like hydrolase
MEDPMIKA_01120 0.0 - - - L - - - PD-(D/E)XK nuclease superfamily
MEDPMIKA_01121 4.3e-141 - - - S - - - Putative auto-transporter adhesin, head GIN domain
MEDPMIKA_01122 0.0 addA - - L - - - UvrD/REP helicase N-terminal domain
MEDPMIKA_01123 9.45e-261 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
MEDPMIKA_01124 5.41e-127 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_01125 2.22e-22 - - - U - - - Belongs to the peptidase S26 family
MEDPMIKA_01126 2.12e-174 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MEDPMIKA_01127 1.07e-165 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MEDPMIKA_01128 4.14e-81 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MEDPMIKA_01129 3.07e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MEDPMIKA_01130 5.24e-299 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_01134 1.83e-150 - - - - - - - -
MEDPMIKA_01135 2.09e-45 - - - - - - - -
MEDPMIKA_01137 1.77e-72 - - - - - - - -
MEDPMIKA_01141 3.45e-29 - - - - - - - -
MEDPMIKA_01143 6.89e-187 recD 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 UvrD-like helicase C-terminal domain
MEDPMIKA_01144 3.4e-30 - - - S - - - COG NOG16623 non supervised orthologous group
MEDPMIKA_01147 0.0 - - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MEDPMIKA_01148 2.56e-86 - - - - - - - -
MEDPMIKA_01149 1.2e-236 - - - L - - - DNA primase
MEDPMIKA_01150 2.74e-195 - - - S - - - Domain of unknown function (DUF4121)
MEDPMIKA_01151 1.42e-245 - - - - - - - -
MEDPMIKA_01153 6.99e-108 - - - - - - - -
MEDPMIKA_01158 3.75e-285 - 2.7.11.1 - S ko:K07154 - ko00000,ko01000,ko01001,ko02048 Pfam:HipA_N
MEDPMIKA_01159 0.0 - - - S - - - Protein of unknown function (DUF1524)
MEDPMIKA_01160 4.6e-248 - - - S - - - Protein of unknown function DUF262
MEDPMIKA_01161 1.36e-264 - - - S - - - ATPase (AAA superfamily)
MEDPMIKA_01162 4.27e-150 - - - S - - - Protein of unknown function (DUF2971)
MEDPMIKA_01163 1.17e-140 - - - L - - - Domain of unknown function (DUF4357)
MEDPMIKA_01164 6.14e-52 - - - - - - - -
MEDPMIKA_01167 4.68e-251 - 2.1.1.72, 3.1.21.3 - V ko:K01154,ko:K03427 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
MEDPMIKA_01168 0.0 - 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 type III restriction protein res subunit
MEDPMIKA_01169 2.18e-37 - - - K - - - Helix-turn-helix XRE-family like proteins
MEDPMIKA_01170 1.08e-97 - - - - - - - -
MEDPMIKA_01171 3.72e-211 - - - U - - - Relaxase mobilization nuclease domain protein
MEDPMIKA_01172 6.15e-260 - - - L - - - COG NOG08810 non supervised orthologous group
MEDPMIKA_01173 0.0 - - - S - - - Protein of unknown function (DUF3987)
MEDPMIKA_01174 2.98e-78 - - - K - - - Excisionase
MEDPMIKA_01175 4.08e-75 - - - - - - - -
MEDPMIKA_01176 2.28e-154 - - - - - - - -
MEDPMIKA_01177 5.49e-131 - - - - - - - -
MEDPMIKA_01178 3.62e-269 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_01179 1.54e-171 - - - L - - - DNA binding domain, excisionase family
MEDPMIKA_01180 3.89e-267 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MEDPMIKA_01181 1.53e-271 mltD - - M ko:K08307 - ko00000,ko01000,ko01011 Transglycosylase SLT domain
MEDPMIKA_01182 3.6e-250 - - - - - - - -
MEDPMIKA_01183 6.95e-184 parB - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MEDPMIKA_01184 3.73e-169 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain
MEDPMIKA_01185 4.39e-167 sagE - - S ko:K07052 - ko00000 CAAX amino terminal protease family
MEDPMIKA_01186 9.84e-173 - - - O - - - COG NOG23400 non supervised orthologous group
MEDPMIKA_01187 3.42e-299 surA 5.2.1.8 - M ko:K03771 - ko00000,ko01000,ko03110 PPIC-type PPIASE domain
MEDPMIKA_01188 0.0 lptD - - M - - - OstA-like protein
MEDPMIKA_01189 1.38e-265 araJ - - EGP ko:K08156 - ko00000,ko02000 Major Facilitator Superfamily
MEDPMIKA_01190 2.53e-107 - - - I - - - NUDIX domain
MEDPMIKA_01191 5.08e-260 ybdG_2 - - M ko:K16053 - ko00000,ko02000 Mechanosensitive ion channel
MEDPMIKA_01192 0.0 - - - P ko:K07085 - ko00000 TrkA C-terminal domain protein
MEDPMIKA_01193 4.01e-282 - - - C - - - Acetyl-CoA hydrolase transferase
MEDPMIKA_01194 2.82e-271 alaC - - E - - - Aminotransferase, class I
MEDPMIKA_01195 1.18e-101 iorB 1.2.7.8 - C ko:K00180 - br01601,ko00000,ko01000 Pyruvate ferredoxin/flavodoxin oxidoreductase
MEDPMIKA_01196 0.0 iorA 1.2.7.8 - C ko:K00179 - br01601,ko00000,ko01000 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
MEDPMIKA_01197 1.84e-147 - - - K ko:K05799 - ko00000,ko03000 FCD
MEDPMIKA_01198 2.97e-58 - - - K - - - DNA-binding transcription factor activity
MEDPMIKA_01199 2.18e-34 - - - C - - - 4Fe-4S binding domain
MEDPMIKA_01200 5.75e-98 - - - O - - - Belongs to the thioredoxin family
MEDPMIKA_01201 1.1e-271 tolC - - MU - - - Outer membrane efflux protein
MEDPMIKA_01202 0.0 bepE_4 - - V ko:K03296,ko:K18138 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MEDPMIKA_01203 1.94e-207 - - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Biotin-lipoyl like
MEDPMIKA_01204 1.26e-270 - - - L - - - Arm DNA-binding domain
MEDPMIKA_01206 2.88e-63 - - - S - - - Helix-turn-helix domain
MEDPMIKA_01208 1.07e-19 - - - - - - - -
MEDPMIKA_01209 4.59e-246 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MEDPMIKA_01211 3.61e-78 - - - S - - - PFAM ORF6N domain
MEDPMIKA_01212 1.93e-37 - - - S ko:K19158 - ko00000,ko01000,ko02048 addiction module toxin, Txe YoeB family
MEDPMIKA_01213 4.71e-22 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
MEDPMIKA_01214 2.89e-28 - - - K - - - DNA-binding helix-turn-helix protein
MEDPMIKA_01219 4.59e-25 - - - CO - - - AhpC Tsa family
MEDPMIKA_01220 2.83e-110 - - - CO - - - AhpC TSA family
MEDPMIKA_01221 1.17e-129 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MEDPMIKA_01222 1.01e-189 - - - CO - - - Domain of unknown function (DUF4369)
MEDPMIKA_01223 1.36e-163 lpxD 2.3.1.191 - M ko:K02536 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MEDPMIKA_01224 2.9e-99 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MEDPMIKA_01225 1.85e-75 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor
MEDPMIKA_01226 5.84e-161 nagZ2 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
MEDPMIKA_01227 5.5e-11 - - - S - - - Domain of unknown function (DUF1735)
MEDPMIKA_01228 4.93e-92 - - - S - - - phosphatase family
MEDPMIKA_01229 0.0 - - - S ko:K21572 - ko00000,ko02000 RagB SusD family protein
MEDPMIKA_01230 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_01231 7.23e-138 - - - PT - - - Fe2 -dicitrate sensor, membrane component
MEDPMIKA_01232 1.13e-93 - - - - - - - -
MEDPMIKA_01233 4.4e-118 - - - E - - - branched-chain-amino-acid transaminase activity
MEDPMIKA_01234 5.64e-235 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III, delta' subunit
MEDPMIKA_01235 3.07e-301 tilS 6.3.4.19 - D ko:K04075 - ko00000,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MEDPMIKA_01236 1.25e-219 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MEDPMIKA_01238 7.49e-315 - - - H - - - Domain of unknown function (DUF4301)
MEDPMIKA_01240 1.39e-95 - - - C ko:K02121 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Produces ATP from ADP in the presence of a proton gradient across the membrane
MEDPMIKA_01241 7.76e-175 - - - C - - - Protein of unknown function (DUF2764)
MEDPMIKA_01242 0.0 atpA 3.6.3.14, 3.6.3.15 - C ko:K02117 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
MEDPMIKA_01243 3.14e-311 ntpB - - C ko:K02118 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 ATP synthase alpha beta family, nucleotide-binding domain
MEDPMIKA_01244 2.7e-131 - - - C ko:K02120 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 ATP synthase subunit D
MEDPMIKA_01245 0.0 - - - C ko:K02123 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Belongs to the V-ATPase 116 kDa subunit family
MEDPMIKA_01246 3.94e-90 - - - C ko:K02124 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 ATP synthase subunit C
MEDPMIKA_01247 0.0 rnr - - J ko:K12573,ko:K12585 ko03018,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MEDPMIKA_01248 2.06e-242 amaA - - S ko:K01436 - ko00000,ko01000,ko01002 Peptidase dimerisation domain
MEDPMIKA_01249 7.65e-223 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
MEDPMIKA_01250 0.0 metH 2.1.1.13 - E ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 B12 binding domain
MEDPMIKA_01251 1.26e-150 - 2.3.2.5 - M ko:K00683 - ko00000,ko01000 Glutamine cyclotransferase
MEDPMIKA_01252 2.01e-287 tig - - O ko:K03545 - ko00000 Bacterial trigger factor protein (TF)
MEDPMIKA_01253 7.38e-148 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MEDPMIKA_01254 1.44e-293 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MEDPMIKA_01255 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the transketolase family
MEDPMIKA_01256 7.44e-291 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MEDPMIKA_01257 0.0 htrA - - M - - - Trypsin
MEDPMIKA_01258 2.19e-190 rpoD - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEDPMIKA_01260 9.8e-26 - - - K - - - Transcriptional regulator, GntR family
MEDPMIKA_01262 4.1e-65 cbiO - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MEDPMIKA_01263 1.06e-155 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MEDPMIKA_01264 1.64e-190 - - - KT - - - BlaR1 peptidase M56
MEDPMIKA_01265 2.95e-70 - - - K - - - Penicillinase repressor
MEDPMIKA_01266 1.24e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MEDPMIKA_01267 4.03e-60 - - - - - - - -
MEDPMIKA_01268 1.17e-247 yaaT - - S - - - PSP1 C-terminal conserved region
MEDPMIKA_01269 1.17e-301 norM - - V ko:K03327 - ko00000,ko02000 Polysaccharide biosynthesis C-terminal domain
MEDPMIKA_01272 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
MEDPMIKA_01273 1.53e-107 - - - S ko:K07095 - ko00000 Calcineurin-like phosphoesterase superfamily domain
MEDPMIKA_01274 1.82e-293 rarA - - L ko:K07478 - ko00000 MgsA AAA+ ATPase C terminal
MEDPMIKA_01275 1.88e-18 - - - - - - - -
MEDPMIKA_01276 1.08e-118 - - - O - - - Domain of unknown function (DUF4861)
MEDPMIKA_01277 0.0 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_01279 1.9e-56 - - - - - - - -
MEDPMIKA_01280 3.48e-218 - - - L - - - COG NOG19076 non supervised orthologous group
MEDPMIKA_01281 6.94e-59 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 regulation of translation
MEDPMIKA_01282 2.08e-167 - 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Phosphoadenosine phosphosulfate reductase family
MEDPMIKA_01283 1.22e-216 - - - C - - - radical SAM domain protein
MEDPMIKA_01284 8.27e-220 - 2.1.1.72 - H ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 D12 class N6 adenine-specific DNA methyltransferase
MEDPMIKA_01286 0.0 - - - - - - - -
MEDPMIKA_01287 0.0 - - - - - - - -
MEDPMIKA_01289 2.88e-113 - - - - - - - -
MEDPMIKA_01291 0.0 - - - L - - - Helicase conserved C-terminal domain
MEDPMIKA_01292 0.0 - - - - - - - -
MEDPMIKA_01293 3.18e-196 - - - S - - - KilA-N
MEDPMIKA_01294 1.2e-49 - - - K - - - sequence-specific DNA binding
MEDPMIKA_01297 0.0 - - - S - - - Mu-like prophage FluMu protein gp28
MEDPMIKA_01299 2.2e-175 - - - - - - - -
MEDPMIKA_01300 0.0 - - - - - - - -
MEDPMIKA_01302 2.17e-139 - - - - - - - -
MEDPMIKA_01305 6.84e-121 - - - - - - - -
MEDPMIKA_01306 6.02e-146 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
MEDPMIKA_01307 2e-112 - - - - - - - -
MEDPMIKA_01309 6.63e-06 - - - S - - - Leucine-rich repeat (LRR) protein
MEDPMIKA_01310 5.95e-239 - - - G - - - exo-alpha-(2->6)-sialidase activity
MEDPMIKA_01311 0.0 - - - - - - - -
MEDPMIKA_01313 4e-131 - - - U ko:K05595 - ko00000,ko02000 MarC family integral membrane protein
MEDPMIKA_01314 2.97e-167 - - - L - - - DNA metabolism protein
MEDPMIKA_01315 4.05e-285 - - - S - - - DNA-binding protein with the Helix-hairpin-helix motif
MEDPMIKA_01316 9.31e-52 ykfA - - S - - - RNA recognition motif
MEDPMIKA_01317 3.57e-62 cspG - - K - - - Cold-shock DNA-binding domain protein
MEDPMIKA_01318 8.19e-259 - - - P - - - Phosphate-selective porin O and P
MEDPMIKA_01319 3.82e-110 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 3' exoribonuclease, RNase T-like
MEDPMIKA_01320 6.74e-186 - - - G - - - Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MEDPMIKA_01321 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Fibronectin type III-like domain
MEDPMIKA_01322 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MEDPMIKA_01324 3.99e-315 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MEDPMIKA_01325 1.62e-58 - - - CO - - - Thioredoxin
MEDPMIKA_01326 5.97e-176 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MEDPMIKA_01327 2.09e-105 spoU - - J - - - SpoU rRNA Methylase family
MEDPMIKA_01329 0.0 glnS 6.1.1.18 - J ko:K01886 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 tRNA synthetases class I (E and Q), anti-codon binding domain
MEDPMIKA_01330 2.39e-75 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEDPMIKA_01331 2.31e-59 - - - - - - - -
MEDPMIKA_01332 4.39e-223 - - - S ko:K07011 - ko00000 Glycosyl transferase family group 2
MEDPMIKA_01333 2.51e-190 waaM 2.3.1.241 - M ko:K02517 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Bacterial lipid A biosynthesis acyltransferase
MEDPMIKA_01334 8.86e-287 - - - S - - - Domain of unknown function (DUF389)
MEDPMIKA_01335 1.58e-148 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MEDPMIKA_01336 3.46e-68 - - - M - - - Membrane
MEDPMIKA_01337 4.65e-253 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
MEDPMIKA_01338 7.65e-11 - - - S - - - Fimbrillin-like
MEDPMIKA_01339 2.25e-46 - - - S - - - C terminal of Calcineurin-like phosphoesterase
MEDPMIKA_01341 8.76e-174 - - - P ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_01342 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_01343 3.62e-39 - - - PT - - - Domain of unknown function (DUF4974)
MEDPMIKA_01344 4.75e-34 - - - K - - - Sigma-70, region 4
MEDPMIKA_01345 1.07e-59 - - - S - - - Endonuclease/Exonuclease/phosphatase family
MEDPMIKA_01346 4.17e-242 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MEDPMIKA_01347 0.0 gltX 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MEDPMIKA_01348 3.03e-241 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
MEDPMIKA_01349 0.0 - - - P ko:K02014 - ko00000,ko02000 TonB dependent receptor
MEDPMIKA_01350 6.45e-100 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MEDPMIKA_01351 7.88e-91 - - - N - - - Trehalose utilisation
MEDPMIKA_01352 7.17e-77 - - - S - - - YjbR
MEDPMIKA_01354 1.16e-266 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 D-mannonate dehydratase (UxuA)
MEDPMIKA_01355 2.68e-167 uxuB - - IQ - - - Oxidoreductase, short chain dehydrogenase reductase family protein
MEDPMIKA_01356 1.51e-203 - - - K ko:K02529 - ko00000,ko03000 Psort location Cytoplasmic, score
MEDPMIKA_01357 6.05e-222 - - - I - - - lipid kinase, YegS Rv2252 BmrU family
MEDPMIKA_01358 3.28e-313 pepD_2 - - E ko:K01270 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Peptidase family M20/M25/M40
MEDPMIKA_01359 4.75e-195 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
MEDPMIKA_01360 1.48e-120 - - - M - - - Outer membrane protein beta-barrel domain
MEDPMIKA_01361 8.98e-225 - - - G - - - Transporter, major facilitator family protein
MEDPMIKA_01362 0.0 ybaL_1 - - PT - - - Transporter, CPA2 family
MEDPMIKA_01363 1.04e-306 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MEDPMIKA_01364 1.17e-35 rubR - - C - - - Rubredoxin
MEDPMIKA_01365 2.55e-110 - - - S - - - Bacterial PH domain
MEDPMIKA_01366 3.6e-132 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MEDPMIKA_01367 1.49e-277 - - - M - - - Peptidase family M23
MEDPMIKA_01368 1.07e-239 lpxK 2.7.1.130 - M ko:K00912 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
MEDPMIKA_01369 3.23e-181 xapA 2.4.2.1 - F ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MEDPMIKA_01370 2.15e-89 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
MEDPMIKA_01372 5.91e-87 - - - K - - - LytTr DNA-binding domain
MEDPMIKA_01373 5.02e-186 - - - S ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_01374 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_01375 0.0 - - - O - - - Domain of unknown function (DUF5117)
MEDPMIKA_01376 1.45e-252 - - - T - - - Histidine kinase
MEDPMIKA_01377 2.32e-139 - - - S - - - Oxidoreductase, short chain dehydrogenase reductase family
MEDPMIKA_01379 1.32e-92 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 Cytidine and deoxycytidylate deaminase zinc-binding region
MEDPMIKA_01380 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MEDPMIKA_01382 2.19e-189 - - - S - - - Protein of unknown function (DUF2851)
MEDPMIKA_01383 6.21e-68 yitW - - S - - - FeS assembly SUF system protein
MEDPMIKA_01384 6.59e-81 sufE - - S ko:K02426 - ko00000 Fe-S metabolism associated domain
MEDPMIKA_01385 0.0 pafA - - S - - - Type I phosphodiesterase nucleotide pyrophosphatase
MEDPMIKA_01386 2.75e-190 - - - E - - - GSCFA family
MEDPMIKA_01387 2.46e-163 ispE 2.7.1.148 - I ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MEDPMIKA_01388 4.75e-96 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose/Galactose Isomerase
MEDPMIKA_01389 2.04e-68 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
MEDPMIKA_01390 1.74e-24 - - - O ko:K03668 - ko00000 response to heat
MEDPMIKA_01391 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MEDPMIKA_01392 1.53e-209 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MEDPMIKA_01393 1.5e-279 maeB 1.1.1.38, 1.1.1.40 - C ko:K00027,ko:K00029 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
MEDPMIKA_01394 1.02e-231 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MEDPMIKA_01396 5.37e-115 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MEDPMIKA_01397 2.5e-160 - - - K - - - DNA-templated transcription, initiation
MEDPMIKA_01399 5.74e-125 - - - K - - - Transcriptional regulator
MEDPMIKA_01400 1.93e-138 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Lumazine binding domain
MEDPMIKA_01401 1.66e-228 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEDPMIKA_01402 5.86e-195 lgt - - M - - - Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MEDPMIKA_01403 3.12e-125 - - - - - - - -
MEDPMIKA_01404 8.62e-97 - - - S - - - GtrA-like protein
MEDPMIKA_01405 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MEDPMIKA_01406 3.56e-19 - - - H - - - Methyltransferase domain
MEDPMIKA_01407 4.06e-40 - - - H - - - Methyltransferase domain protein
MEDPMIKA_01408 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MEDPMIKA_01409 2.5e-101 smpB - - O ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MEDPMIKA_01410 1.82e-159 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_01411 1.82e-143 yeaZ - - O ko:K14742 - ko00000,ko03016 Glycoprotease family
MEDPMIKA_01412 4.02e-88 - - - - - - - -
MEDPMIKA_01413 4.62e-304 - - - S - - - Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MEDPMIKA_01414 1.22e-166 - - - G - - - Xylose isomerase-like TIM barrel
MEDPMIKA_01415 0.0 - - - S - - - Fibronectin type III domain
MEDPMIKA_01416 2.67e-286 - - - GM ko:K21572 - ko00000,ko02000 COG NOG26302 non supervised orthologous group
MEDPMIKA_01417 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_01418 3.32e-65 - - - PT - - - Domain of unknown function (DUF4974)
MEDPMIKA_01420 3.54e-100 rpoE3 - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MEDPMIKA_01421 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
MEDPMIKA_01422 3.01e-219 rmuC - - S ko:K09760 - ko00000 RmuC family
MEDPMIKA_01423 6.29e-126 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MEDPMIKA_01424 1.35e-114 - - - S ko:K07023 - ko00000 HD domain
MEDPMIKA_01425 0.0 yheS_3 - - S ko:K06158 - ko00000,ko03012 ABC transporter
MEDPMIKA_01426 6.71e-158 trmH 2.1.1.185 - J ko:K03218,ko:K03437 - ko00000,ko01000,ko03009,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEDPMIKA_01427 0.0 - - - I - - - Psort location CytoplasmicMembrane, score 10.00
MEDPMIKA_01428 1.62e-113 - - - S ko:K07043 - ko00000 Metal-dependent hydrolase
MEDPMIKA_01429 3.97e-146 glpT - - G ko:K02445 - ko00000,ko02000 COG2271 Sugar phosphate permease
MEDPMIKA_01430 0.0 glpA 1.1.5.3 - C ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
MEDPMIKA_01431 3.5e-167 agaR - - K ko:K02081 - ko00000,ko03000 Transcriptional regulator, DeoR family
MEDPMIKA_01432 1.28e-158 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MEDPMIKA_01433 7.91e-270 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MEDPMIKA_01434 2.47e-274 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_01436 2.04e-20 - - - S - - - COG NOG37914 non supervised orthologous group
MEDPMIKA_01437 4.55e-51 - - - U - - - Relaxase/Mobilisation nuclease domain
MEDPMIKA_01438 5.69e-35 - - - U - - - Relaxase/Mobilisation nuclease domain
MEDPMIKA_01439 1.09e-57 - - - F - - - Cytidylate kinase-like family
MEDPMIKA_01440 7.23e-37 - - - - - - - -
MEDPMIKA_01442 4.56e-31 - - - M - - - Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MEDPMIKA_01443 2.03e-118 - - - O - - - Peptidase, S8 S53 family
MEDPMIKA_01446 8.29e-137 - - - S ko:K21572 - ko00000,ko02000 Pfam:SusD
MEDPMIKA_01447 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_01449 7.2e-197 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEDPMIKA_01450 1.72e-19 - - - T - - - Y_Y_Y domain
MEDPMIKA_01452 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEDPMIKA_01453 0.0 - 3.2.1.4 GH5,GH9 S ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 metallopeptidase activity
MEDPMIKA_01454 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_01455 0.0 - - - GM ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_01456 2.77e-300 - - - - - - - -
MEDPMIKA_01457 0.0 glaB - - M - - - Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
MEDPMIKA_01458 0.0 - - - M - - - Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
MEDPMIKA_01459 5.33e-245 - - - S ko:K06889 - ko00000 of the alpha beta superfamily
MEDPMIKA_01460 0.0 - - - G - - - Glycogen debranching enzyme
MEDPMIKA_01461 0.0 glaB - - M - - - Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
MEDPMIKA_01462 8.08e-119 - - - T - - - cyclic nucleotide-binding
MEDPMIKA_01463 2.02e-248 - - - V - - - Na driven multidrug efflux pump
MEDPMIKA_01464 5.1e-132 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_01465 5.9e-70 - - - S - - - Helix-turn-helix domain
MEDPMIKA_01466 5.93e-60 - - - K - - - Helix-turn-helix domain
MEDPMIKA_01467 5.71e-287 - - - - - - - -
MEDPMIKA_01468 0.0 - - - S - - - Domain of unknown function (DUF4906)
MEDPMIKA_01470 2.29e-222 - - - C - - - radical SAM domain protein
MEDPMIKA_01471 0.0 - - - M - - - chlorophyll binding
MEDPMIKA_01472 8.62e-126 - - - M - - - chlorophyll binding
MEDPMIKA_01473 0.0 - - - S - - - Domain of unknown function (DUF4906)
MEDPMIKA_01474 4.25e-89 - - - S - - - Domain of unknown function (DUF4906)
MEDPMIKA_01477 5.25e-189 - - - G - - - Glycosyl hydrolases family 18
MEDPMIKA_01478 2.76e-271 - - - G - - - Glycosyl hydrolases family 18
MEDPMIKA_01479 0.0 - - - S - - - Concanavalin A-like lectin/glucanases superfamily
MEDPMIKA_01480 3.04e-203 - - - G - - - Putative glycoside hydrolase Family 18, chitinase_18
MEDPMIKA_01481 0.0 - - - S - - - Susd and RagB outer membrane lipoprotein
MEDPMIKA_01482 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_01483 2.4e-229 - - - PT - - - Sigma factor regulatory protein, FecR PupR family
MEDPMIKA_01484 6.41e-123 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor
MEDPMIKA_01485 3.62e-84 - - - S - - - PFAM ORF6N domain
MEDPMIKA_01486 5.16e-89 - - - S - - - PFAM ORF6N domain
MEDPMIKA_01487 1.56e-68 - - - K - - - BRO family, N-terminal domain
MEDPMIKA_01488 1.61e-296 - - - S - - - Domain of unknown function (DUF4209)
MEDPMIKA_01492 9.77e-283 - - - - - - - -
MEDPMIKA_01493 1.8e-214 - - - - - - - -
MEDPMIKA_01497 1.78e-240 - - - - - - - -
MEDPMIKA_01499 0.0 - - - M - - - chlorophyll binding
MEDPMIKA_01500 0.0 - - - S - - - Domain of unknown function (DUF4906)
MEDPMIKA_01501 1.38e-131 - - - M - - - chlorophyll binding
MEDPMIKA_01502 0.0 - - - S - - - Domain of unknown function (DUF4906)
MEDPMIKA_01503 3.58e-89 - - - S - - - Domain of unknown function (DUF4906)
MEDPMIKA_01505 9e-223 - - - U - - - YWFCY protein
MEDPMIKA_01506 9.33e-11 - - - U - - - COG COG3505 Type IV secretory pathway, VirD4 components
MEDPMIKA_01507 1.76e-49 - - - S - - - RteC protein
MEDPMIKA_01511 3.94e-62 - - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
MEDPMIKA_01516 3.11e-247 - - - S - - - Psort location Cytoplasmic, score
MEDPMIKA_01518 0.0 - - - S ko:K07126,ko:K09973 - ko00000 regulation of response to stimulus
MEDPMIKA_01519 6.75e-195 - - - E - - - Zinc-dependent metalloprotease
MEDPMIKA_01520 4.91e-137 - - - S - - - Chaperone of endosialidase
MEDPMIKA_01521 0.0 - 3.4.21.62, 3.4.21.66 - O ko:K01342,ko:K08651 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Subtilase family
MEDPMIKA_01524 5.64e-313 - - - U - - - Relaxase/Mobilisation nuclease domain
MEDPMIKA_01527 1.9e-184 - - - D - - - COG NOG26689 non supervised orthologous group
MEDPMIKA_01529 1.72e-59 - - - S - - - Psort location CytoplasmicMembrane, score
MEDPMIKA_01530 1.51e-19 - - - U - - - Conjugation system ATPase, TraG family
MEDPMIKA_01531 4.73e-307 - - - U - - - Conjugation system ATPase, TraG family
MEDPMIKA_01533 6.47e-64 - - - S - - - Helix-turn-helix domain
MEDPMIKA_01534 1.02e-55 - - - K ko:K18997 - ko00000,ko03036 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MEDPMIKA_01535 4.69e-30 - - - U ko:K03832 - ko00000,ko02000 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MEDPMIKA_01536 3.58e-241 oadB 4.1.1.3 - C ko:K01572 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Na+-transporting oxaloacetate decarboxylase beta subunit
MEDPMIKA_01537 6.47e-81 mmdC - - I - - - Biotin-requiring enzyme
MEDPMIKA_01538 2.34e-63 - - - C - - - sodium ion export across plasma membrane
MEDPMIKA_01539 0.0 mmdA - - I - - - Carboxyl transferase domain
MEDPMIKA_01540 3.32e-93 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEDPMIKA_01541 4.91e-167 - - - M - - - Glycosyltransferase, group 1 family protein
MEDPMIKA_01542 6.09e-75 - - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
MEDPMIKA_01543 1.42e-251 argK - - E ko:K07588 - ko00000,ko01000 LAO AO transport system ATPase
MEDPMIKA_01546 2.7e-143 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MEDPMIKA_01547 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
MEDPMIKA_01548 2.04e-174 - 1.3.1.22 - S ko:K12343 ko00140,map00140 ko00000,ko00001,ko01000 Psort location CytoplasmicMembrane, score 10.00
MEDPMIKA_01549 9.24e-288 namA - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
MEDPMIKA_01550 1.99e-163 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MEDPMIKA_01551 3.52e-121 - 3.1.3.10, 3.1.3.104 - S ko:K07025,ko:K20866,ko:K21063 ko00010,ko00740,ko01100,ko01110,ko01120,map00010,map00740,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Haloacid dehalogenase-like hydrolase
MEDPMIKA_01555 8.79e-112 - - - S - - - COG1137 ABC-type (unclassified) transport system, ATPase component
MEDPMIKA_01556 1.55e-253 - - - C - - - Radical SAM domain protein
MEDPMIKA_01558 6.79e-38 cspA - - K ko:K03704 - ko00000,ko03000 Cold shock
MEDPMIKA_01559 6.9e-298 pfp 2.7.1.11, 2.7.1.90 - H ko:K00895,ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
MEDPMIKA_01560 2.78e-179 - - - - - - - -
MEDPMIKA_01561 7.87e-92 - - - S - - - Protein of unknown function (DUF1273)
MEDPMIKA_01564 7.68e-131 rbr3A - - C - - - Rubrerythrin
MEDPMIKA_01565 3.43e-192 - - - CO - - - Domain of unknown function (DUF5106)
MEDPMIKA_01566 0.0 gadC - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Amino acid permease
MEDPMIKA_01567 4.22e-220 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
MEDPMIKA_01568 2.14e-100 - - - - - - - -
MEDPMIKA_01569 3.77e-118 - - - S - - - Glycosyltransferase WbsX
MEDPMIKA_01570 7.9e-26 - - - M - - - Glycosyltransferase WbsX
MEDPMIKA_01571 0.0 acd - - I - - - Acyl-CoA dehydrogenase, C-terminal domain
MEDPMIKA_01573 2.29e-220 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
MEDPMIKA_01574 2.91e-187 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
MEDPMIKA_01575 2.01e-307 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MEDPMIKA_01576 7.17e-46 - - - S - - - Leucine rich repeat protein
MEDPMIKA_01577 2.16e-50 - - - - - - - -
MEDPMIKA_01578 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MEDPMIKA_01579 3.94e-187 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MEDPMIKA_01580 4.16e-154 - - - S - - - Domain of unknown function (DUF4919)
MEDPMIKA_01581 1.03e-172 - - - S - - - Clostripain family
MEDPMIKA_01582 4.77e-213 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MEDPMIKA_01583 3.99e-296 dinF - - V ko:K03327 - ko00000,ko02000 MatE
MEDPMIKA_01584 1.1e-168 - 3.1.1.11 - G ko:K01051 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Pectinesterase
MEDPMIKA_01585 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 SAF domain protein
MEDPMIKA_01586 0.0 uxaB 1.1.1.17, 1.1.1.58 - G ko:K00009,ko:K00041 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the mannitol dehydrogenase family. UxaB subfamily
MEDPMIKA_01587 0.0 exuT - - G ko:K08191 - ko00000,ko02000 Major Facilitator
MEDPMIKA_01588 2.43e-144 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
MEDPMIKA_01589 9.24e-237 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Kinase, PfkB family
MEDPMIKA_01590 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
MEDPMIKA_01591 2.53e-240 - 3.1.1.11 - G ko:K01051 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Domain of unknown function (DUF4861)
MEDPMIKA_01592 1.72e-225 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Kinase, PfkB family
MEDPMIKA_01593 5.16e-281 - - - S - - - Tetratricopeptide repeat
MEDPMIKA_01594 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEDPMIKA_01596 4.33e-35 - - - - - - - -
MEDPMIKA_01597 1.66e-97 lolA - - M ko:K03634 - ko00000 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MEDPMIKA_01598 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Ftsk_gamma
MEDPMIKA_01599 2.09e-148 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MEDPMIKA_01600 1.58e-90 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MEDPMIKA_01601 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 DNA Topoisomerase IV
MEDPMIKA_01602 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Type IIA topoisomerase (DNA gyrase topo II, topoisomerase IV), B subunit
MEDPMIKA_01603 9.43e-148 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MEDPMIKA_01604 0.0 - - - P - - - Outer membrane protein beta-barrel family
MEDPMIKA_01605 1.77e-190 - - - EG - - - Psort location CytoplasmicMembrane, score 10.00
MEDPMIKA_01606 2.5e-117 lemA - - S ko:K03744 - ko00000 LemA family
MEDPMIKA_01607 1.75e-161 - - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
MEDPMIKA_01608 1.84e-299 amyB - - G - - - Alpha amylase, catalytic domain
MEDPMIKA_01609 0.0 - 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolase family 65, C-terminal domain
MEDPMIKA_01610 1.61e-113 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 HAD-hyrolase-like
MEDPMIKA_01611 1.82e-151 - - - M ko:K01991 ko02026,map02026 ko00000,ko00001,ko02000 Polysaccharide biosynthesis/export protein
MEDPMIKA_01612 0.0 - - - D - - - Chain length determinant protein
MEDPMIKA_01613 3.02e-79 - - - S - - - phosphatase activity
MEDPMIKA_01614 1.86e-205 - - - JM - - - Nucleotidyl transferase
MEDPMIKA_01615 5.24e-181 - - - D - - - Peptidase family M23
MEDPMIKA_01616 2.34e-249 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MEDPMIKA_01617 5.73e-253 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MEDPMIKA_01618 5e-121 - - - C - - - LUD domain
MEDPMIKA_01619 4.97e-53 - - - M - - - energy transducer activity
MEDPMIKA_01620 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MEDPMIKA_01621 8.2e-183 - 4.1.1.35, 5.1.3.2, 5.1.3.7 - GM ko:K01784,ko:K02473,ko:K08678 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase dehydratase family
MEDPMIKA_01622 5.21e-62 - - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin
MEDPMIKA_01623 2.59e-93 - - - L - - - DNA alkylation repair enzyme
MEDPMIKA_01624 6.51e-173 - - - S - - - Domain of unknown function (DUF4831)
MEDPMIKA_01626 1.45e-239 - - - L - - - Phage integrase SAM-like domain
MEDPMIKA_01627 4e-281 - - - M - - - Protein of unknown function (DUF3575)
MEDPMIKA_01629 7.46e-258 - - - S - - - Fimbrillin-like
MEDPMIKA_01630 7.33e-254 - - - S - - - Fimbrillin-like
MEDPMIKA_01631 0.0 - - - S - - - Domain of unknown function (DUF4906)
MEDPMIKA_01632 7.98e-185 znuC - - P ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MEDPMIKA_01633 5.19e-171 mntA - - P ko:K09815,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Zinc-uptake complex component A periplasmic
MEDPMIKA_01634 2.06e-114 - - - L - - - Pfam Transposase DDE domain
MEDPMIKA_01635 1.05e-162 - - - U - - - Relaxase mobilization nuclease domain protein
MEDPMIKA_01637 1.77e-71 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_01638 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_01639 1.22e-255 - - - P ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_01640 8.32e-14 - - - S ko:K21571 - ko00000 Outer membrane protein SusF_SusE
MEDPMIKA_01642 6.87e-140 imd - - S - - - cellulase activity
MEDPMIKA_01643 5.74e-277 kojP - - G - - - Glycosyl hydrolase family 65 central catalytic domain
MEDPMIKA_01644 0.0 susB 3.2.1.20, 3.2.1.3 GH31,GH97 G ko:K01187,ko:K21574 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl-hydrolase 97 N-terminal
MEDPMIKA_01645 0.0 - - - U - - - Psort location CytoplasmicMembrane, score 10.00
MEDPMIKA_01646 3.09e-123 - - - S - - - Domain of unknown function (DUF4924)
MEDPMIKA_01647 2.34e-102 - - - T - - - COG COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases
MEDPMIKA_01648 4.89e-100 paiA - - K - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_01649 3.81e-28 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MEDPMIKA_01650 4.28e-296 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEDPMIKA_01651 0.0 - - - O - - - Domain of unknown function (DUF5117)
MEDPMIKA_01652 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_01653 1.48e-241 - 1.14.14.47 - GM ko:K00491,ko:K21572 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000,ko02000 epimerase
MEDPMIKA_01654 1.4e-143 - - - S - - - Domain of unknown function (DUF4843)
MEDPMIKA_01655 2.58e-264 - - - - - - - -
MEDPMIKA_01657 7.06e-128 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MEDPMIKA_01658 3.89e-147 - - - - - - - -
MEDPMIKA_01659 0.0 cstA - - T ko:K06200 - ko00000 5TM C-terminal transporter carbon starvation CstA
MEDPMIKA_01661 7.17e-219 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_01664 7.81e-275 - - - JKL - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_01665 2.88e-90 - - - S - - - Protein of unknown function (DUF5131)
MEDPMIKA_01666 3.98e-171 - - - L - - - AAA domain
MEDPMIKA_01667 2.4e-257 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_01668 3.92e-210 - - - - - - - -
MEDPMIKA_01669 5.23e-82 - - - S - - - Region found in RelA / SpoT proteins
MEDPMIKA_01670 1.29e-11 - - - - - - - -
MEDPMIKA_01677 9.41e-178 - - - S - - - non supervised orthologous group
MEDPMIKA_01678 1.11e-220 - - - S - - - COG NOG25284 non supervised orthologous group
MEDPMIKA_01679 0.0 - - - H ko:K02014 - ko00000,ko02000 Outer membrane cobalamin receptor protein
MEDPMIKA_01680 5.59e-308 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEDPMIKA_01681 6.54e-207 - 4.1.1.35, 5.1.3.7 - GM ko:K02473,ko:K08678 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
MEDPMIKA_01682 6.64e-132 copA 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 Heavy-metal-associated domain
MEDPMIKA_01683 3.09e-137 - - - - - - - -
MEDPMIKA_01684 3.59e-134 - - - S ko:K09939 - ko00000 Putative PepSY_TM-like
MEDPMIKA_01685 4.32e-299 - - - S - - - Domain of unknown function (DUF4857)
MEDPMIKA_01686 6.35e-154 - - - - - - - -
MEDPMIKA_01687 3.77e-216 - - - V ko:K01990,ko:K19340 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MEDPMIKA_01688 3.53e-296 - - - S - - - Protein of unknown function (DUF4876)
MEDPMIKA_01689 0.0 - - - - - - - -
MEDPMIKA_01691 0.0 - - - P - - - TonB-dependent Receptor Plug Domain
MEDPMIKA_01692 8.6e-118 fldA - - C ko:K03839 - ko00000 Low-potential electron donor to a number of redox enzymes
MEDPMIKA_01693 8.1e-87 - - - S - - - hmm pf09633
MEDPMIKA_01694 1.33e-57 - 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MEDPMIKA_01695 0.0 - - - O - - - Peptidase, S8 S53 family
MEDPMIKA_01696 3.57e-137 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MEDPMIKA_01698 1.28e-281 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Alpha-galactosidase
MEDPMIKA_01699 0.0 - - - O - - - Highly conserved protein containing a thioredoxin domain
MEDPMIKA_01700 3.42e-31 - - - V ko:K20333 ko02024,map02024 ko00000,ko00001 peptidase activity
MEDPMIKA_01702 3.71e-90 - - - F ko:K21572 - ko00000,ko02000 PFAM RagB SusD
MEDPMIKA_01703 1.7e-308 - - - P - - - TIGRFAM TonB-dependent outer membrane receptor, SusC RagA subfamily, signature region
MEDPMIKA_01704 0.0 - - - C - - - FAD dependent oxidoreductase
MEDPMIKA_01705 7.92e-231 - - - E - - - Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MEDPMIKA_01707 3.09e-85 - - - K ko:K02529,ko:K05499 - ko00000,ko03000 Periplasmic binding protein-like domain
MEDPMIKA_01708 4.07e-279 - 4.2.2.5 PL8 N ko:K19049 - ko00000,ko01000 Polysaccharide lyase family 8, N terminal alpha-helical domain
MEDPMIKA_01709 5.27e-177 - - - G - - - Glycosyl Hydrolase Family 88
MEDPMIKA_01710 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_01711 1.39e-291 - - - P ko:K21572 - ko00000,ko02000 Pfam:SusD
MEDPMIKA_01714 3.17e-227 - - - S - - - Heparinase II/III-like protein
MEDPMIKA_01715 1.33e-217 - - - S - - - COG NOG25375 non supervised orthologous group
MEDPMIKA_01717 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEDPMIKA_01718 5.58e-183 - - - P - - - Sulfatase
MEDPMIKA_01719 1.32e-294 - - - P - - - COG COG3119 Arylsulfatase A and related enzymes
MEDPMIKA_01720 5.86e-292 - - - P - - - Sulfatase
MEDPMIKA_01721 7.33e-231 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
MEDPMIKA_01722 0.0 pbpC 2.4.1.129 GT51 M ko:K05367 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-Binding Protein C-terminus Family
MEDPMIKA_01723 0.0 - - - S ko:K06894 - ko00000 Alpha-2-Macroglobulin
MEDPMIKA_01724 1.45e-311 - - - G - - - Glycosyl hydrolase family 20, catalytic domain
MEDPMIKA_01725 5.69e-220 - - - S - - - Calcineurin-like phosphoesterase
MEDPMIKA_01726 5.18e-151 - - - S - - - Putative polysaccharide deacetylase
MEDPMIKA_01727 4.39e-133 - - - S - - - Flavin reductase-like protein
MEDPMIKA_01728 1.16e-192 xerC - - D ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
MEDPMIKA_01729 1.72e-59 raiA - - J ko:K05808 - ko00000,ko03009 Ribosomal subunit interface protein
MEDPMIKA_01730 3.76e-50 - - - S - - - Domain of unknown function (DUF4493)
MEDPMIKA_01732 3.47e-86 - - - S - - - COG NOG14444 non supervised orthologous group
MEDPMIKA_01734 6.32e-155 - - - S - - - N-terminal domain of galactosyltransferase
MEDPMIKA_01735 6.17e-198 - - - M - - - Stealth protein CR1, conserved region 1
MEDPMIKA_01736 8.27e-190 - 2.7.8.12 GT2 M ko:K09809,ko:K19354 - ko00000,ko01000,ko01003,ko01005 transferase activity, transferring glycosyl groups
MEDPMIKA_01737 0.0 - - - S ko:K07137 - ko00000 FAD binding domain
MEDPMIKA_01739 1.06e-195 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_01740 9.69e-29 - - - S - - - Bacterial mobilization protein MobC
MEDPMIKA_01741 2.72e-99 - - - U - - - Mobilization protein
MEDPMIKA_01742 4.95e-08 - - - - - - - -
MEDPMIKA_01743 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MEDPMIKA_01744 1.24e-280 - - - S - - - FRG
MEDPMIKA_01745 1.63e-245 - - - L - - - COG COG3385 FOG Transposase and inactivated derivatives
MEDPMIKA_01746 1.65e-144 - - - S - - - repeat protein
MEDPMIKA_01747 7.89e-193 - - - S - - - Virulence protein RhuM family
MEDPMIKA_01748 9.09e-08 - - - S - - - regulation of response to stimulus
MEDPMIKA_01750 5.55e-148 - - - - - - - -
MEDPMIKA_01751 6.89e-98 - - - - - - - -
MEDPMIKA_01754 3.16e-202 - - - P ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_01755 3.9e-314 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_01756 1.67e-22 - - - PT - - - Domain of unknown function (DUF4974)
MEDPMIKA_01757 7.52e-19 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor
MEDPMIKA_01758 1.94e-26 - - - S - - - PKD-like family
MEDPMIKA_01760 9.85e-109 - - - S ko:K21572 - ko00000,ko02000 Starch-binding associating with outer membrane
MEDPMIKA_01761 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_01762 5.63e-43 - - - PT - - - COG3712 Fe2 -dicitrate sensor, membrane component
MEDPMIKA_01763 1.1e-11 - - - K ko:K03088 - ko00000,ko03021 DNA-templated transcription, initiation
MEDPMIKA_01764 6.15e-139 hisI 3.5.4.19, 3.6.1.31 - E ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Phosphoribosyl-AMP cyclohydrolase
MEDPMIKA_01765 2.26e-165 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MEDPMIKA_01766 8.33e-148 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidine biosynthesis protein
MEDPMIKA_01767 2.35e-114 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MEDPMIKA_01768 4.25e-251 hisB 3.1.3.15, 4.2.1.19 - E ko:K01089,ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the imidazoleglycerol-phosphate dehydratase family
MEDPMIKA_01769 1.23e-216 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
MEDPMIKA_01770 8.48e-261 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MEDPMIKA_01771 4.38e-184 hisG 2.4.2.17 - E ko:K00765 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 ATP phosphoribosyltransferase
MEDPMIKA_01772 7.97e-104 - - - K - - - Cupin domain protein
MEDPMIKA_01773 0.0 acsA 6.2.1.1, 6.2.1.32 - I ko:K01895,ko:K08295 ko00010,ko00620,ko00627,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00627,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 AMP-binding enzyme
MEDPMIKA_01775 1.04e-21 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor
MEDPMIKA_01776 7.32e-58 - - - PT - - - COGs COG3712 Fe2 -dicitrate sensor membrane component
MEDPMIKA_01777 2.22e-315 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_01778 3.76e-154 - - - F ko:K21572 - ko00000,ko02000 PFAM RagB SusD
MEDPMIKA_01779 9.49e-82 - - - S - - - Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MEDPMIKA_01781 1.62e-71 - - - M - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_01782 2.89e-237 - - - L - - - Arm DNA-binding domain
MEDPMIKA_01784 3.92e-61 - - - S - - - Helix-turn-helix domain
MEDPMIKA_01786 1.99e-17 - - - K - - - DNA-binding transcription factor activity
MEDPMIKA_01787 1.12e-205 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MEDPMIKA_01792 7.19e-43 - - - D - - - Phage-related minor tail protein
MEDPMIKA_01795 1.49e-132 - - - K - - - BRO family, N-terminal domain
MEDPMIKA_01796 2.1e-117 fic - - D ko:K04095 - ko00000,ko03036 FIC family
MEDPMIKA_01797 2.25e-204 - - - S - - - Virulence protein RhuM family
MEDPMIKA_01798 4.62e-44 - - - K - - - Cro/C1-type HTH DNA-binding domain
MEDPMIKA_01805 2.7e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 50S ribosomal protein L31 type B
MEDPMIKA_01806 2.1e-131 - - - S - - - Transposase
MEDPMIKA_01807 9.49e-190 - - - K - - - Transcriptional regulator
MEDPMIKA_01808 2.65e-85 - - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase, gnat family
MEDPMIKA_01812 3.08e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MEDPMIKA_01814 6.9e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 SecE/Sec61-gamma subunits of protein translocation complex
MEDPMIKA_01815 8.25e-125 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MEDPMIKA_01816 1.87e-97 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MEDPMIKA_01817 7.64e-155 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MEDPMIKA_01818 1.38e-108 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L10
MEDPMIKA_01819 4.44e-61 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MEDPMIKA_01821 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEDPMIKA_01822 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEDPMIKA_01824 6.33e-16 - - - U - - - Relaxase/Mobilisation nuclease domain
MEDPMIKA_01825 3.1e-76 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor
MEDPMIKA_01826 3.47e-151 - - - PT - - - Sigma factor regulatory protein, FecR PupR family
MEDPMIKA_01827 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_01828 1.98e-77 - - - S - - - non supervised orthologous group
MEDPMIKA_01829 7.33e-125 - - - G - - - Putative glycoside hydrolase Family 18, chitinase_18
MEDPMIKA_01830 2.67e-05 psrP1 1.11.1.5, 3.1.3.8, 4.2.2.2 - G ko:K00428,ko:K01083,ko:K01728 ko00040,ko00562,ko02024,map00040,map00562,map02024 ko00000,ko00001,ko01000 Glucose / Sorbosone dehydrogenase
MEDPMIKA_01831 0.0 nagZ3 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
MEDPMIKA_01833 3.82e-168 yfbB - - I - - - Ndr family
MEDPMIKA_01834 1.96e-25 - - - - - - - -
MEDPMIKA_01835 2.81e-168 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MEDPMIKA_01836 6.05e-169 - 1.5.1.38, 1.5.1.39 - C ko:K19285,ko:K19286 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Nitroreductase family
MEDPMIKA_01837 0.0 - - - M - - - Surface antigen
MEDPMIKA_01838 1.85e-179 - - - K - - - helix_turn_helix, arabinose operon control protein
MEDPMIKA_01839 7.95e-82 ompH - - M ko:K06142 - ko00000 Outer membrane protein (OmpH-like)
MEDPMIKA_01840 2.37e-95 ompH - - M ko:K06142 - ko00000 membrane
MEDPMIKA_01841 0.0 yaeT - - M ko:K07277 - ko00000,ko02000,ko03029 Outer membrane protein assembly complex, YaeT protein
MEDPMIKA_01842 1.97e-149 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MEDPMIKA_01843 5.39e-178 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MEDPMIKA_01844 2.18e-157 pdxJ 2.6.99.2 - H ko:K03474 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MEDPMIKA_01845 2.42e-118 estA - - E - - - GDSL-like Lipase/Acylhydrolase
MEDPMIKA_01846 1.49e-308 cca 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 tRNA nucleotidyltransferase poly(A) polymerase
MEDPMIKA_01847 3.72e-195 - - - EG - - - COG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MEDPMIKA_01848 2.88e-191 - - - EG - - - EamA-like transporter family
MEDPMIKA_01849 2.88e-78 - - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
MEDPMIKA_01850 1.99e-124 rimN 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Belongs to the SUA5 family
MEDPMIKA_01851 1.07e-82 gloA 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Lactoylglutathione lyase
MEDPMIKA_01852 8.79e-154 yebC - - K - - - transcriptional regulatory protein
MEDPMIKA_01853 1.09e-103 - 1.6.3.4 - C ko:K22405 - ko00000,ko01000 Rubrerythrin
MEDPMIKA_01855 8.71e-264 - - - I - - - PAP2 family
MEDPMIKA_01856 0.0 - 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
MEDPMIKA_01857 1.63e-296 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MEDPMIKA_01858 0.0 mrdA 3.4.16.4 - M ko:K05515 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein dimerisation domain
MEDPMIKA_01859 2.31e-90 mreD - - S - - - rod shape-determining protein MreD
MEDPMIKA_01860 8.76e-166 mreC - - M ko:K03570 - ko00000,ko03036 rod shape-determining protein MreC
MEDPMIKA_01861 6.41e-237 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein, MreB Mrl family
MEDPMIKA_01862 2.73e-220 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MEDPMIKA_01863 4.62e-292 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MEDPMIKA_01864 3.3e-05 opuAC - - S ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 dextransucrase activity
MEDPMIKA_01865 0.0 gdh 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
MEDPMIKA_01866 0.0 ppsA - - GKT - - - Pyruvate phosphate dikinase, PEP/pyruvate binding domain
MEDPMIKA_01867 1.62e-296 - - - K - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_01868 4.85e-257 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
MEDPMIKA_01869 5.54e-202 preA 1.3.98.1 - F ko:K00226 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
MEDPMIKA_01870 1.85e-114 - - - FJ ko:K06950 - ko00000 HD domain protein
MEDPMIKA_01871 1.97e-283 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MEDPMIKA_01872 9.16e-51 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MEDPMIKA_01873 1.5e-07 - - - - - - - -
MEDPMIKA_01874 1.14e-293 rimO 2.8.4.4 - H ko:K14441 - ko00000,ko01000,ko03009 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
MEDPMIKA_01875 8.08e-216 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MEDPMIKA_01876 1.69e-183 - - - - - - - -
MEDPMIKA_01877 4.98e-215 - - - M - - - Glycosyl transferases group 1
MEDPMIKA_01878 1.44e-158 - - - M - - - Glycosyltransferase, group 1 family protein
MEDPMIKA_01879 2.05e-24 - - - S - - - Domain of unknown function (DUF4295)
MEDPMIKA_01880 6.96e-33 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MEDPMIKA_01881 1.02e-46 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MEDPMIKA_01882 1.71e-267 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MEDPMIKA_01883 2.71e-247 pyrD 1.3.5.2 - F ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MEDPMIKA_01884 2.33e-203 - 1.1.1.290 - CH ko:K03473 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate
MEDPMIKA_01885 3.78e-227 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
MEDPMIKA_01886 7.32e-302 nhaA - - P ko:K03313 - ko00000,ko02000 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MEDPMIKA_01887 2.25e-132 - 5.2.1.8 - O ko:K01802,ko:K03772 - ko00000,ko01000,ko03110 Peptidyl-prolyl cis-trans isomerase
MEDPMIKA_01888 5.11e-237 fklB 5.2.1.8 - O ko:K03772,ko:K03773 - ko00000,ko01000,ko03110 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
MEDPMIKA_01889 8.62e-77 - - - S - - - Domain of unknown function (DUF3127)
MEDPMIKA_01890 2.21e-44 - - - S - - - Endonuclease exonuclease phosphatase family
MEDPMIKA_01891 3.77e-143 - - - E - - - N-terminus of Esterase_SGNH_hydro-type
MEDPMIKA_01892 1.2e-47 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor
MEDPMIKA_01893 6.63e-24 - - - PT - - - Domain of unknown function (DUF4974)
MEDPMIKA_01894 0.0 - - - P - - - TonB dependent receptor
MEDPMIKA_01895 1.32e-184 - - - S ko:K21572 - ko00000,ko02000 Starch-binding protein
MEDPMIKA_01896 1e-71 - - - N - - - Endonuclease Exonuclease Phosphatase
MEDPMIKA_01897 6.35e-72 - - - S - - - PKD domain
MEDPMIKA_01898 0.0 - - - O - - - Domain of unknown function (DUF5117)
MEDPMIKA_01899 7.2e-191 - - - O - - - Domain of unknown function (DUF5117)
MEDPMIKA_01900 3.88e-204 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MEDPMIKA_01901 6.52e-123 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MEDPMIKA_01902 2.57e-18 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MEDPMIKA_01904 8.95e-291 - 2.3.1.29 - E ko:K00639 ko00260,map00260 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
MEDPMIKA_01905 5.49e-82 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_01906 1.18e-295 - - - S - - - Protein of unknown function DUF262
MEDPMIKA_01907 7.44e-108 - - - - - - - -
MEDPMIKA_01908 6.62e-80 - - - K - - - Helix-turn-helix domain
MEDPMIKA_01909 0.0 - - - S - - - COG NOG11635 non supervised orthologous group
MEDPMIKA_01910 1.44e-258 - - - L - - - COG NOG08810 non supervised orthologous group
MEDPMIKA_01911 9.42e-228 - - - L - - - plasmid recombination enzyme
MEDPMIKA_01914 1.76e-14 - - - K - - - TIGRFAM DNA binding domain, excisionase family
MEDPMIKA_01915 7.2e-216 sstT - - U - - - Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEDPMIKA_01916 4.22e-169 - - - C - - - radical SAM domain protein
MEDPMIKA_01917 1.29e-145 yaaA - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MEDPMIKA_01919 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MEDPMIKA_01920 1.31e-152 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MEDPMIKA_01921 9.99e-108 - - - CO - - - AhpC TSA family
MEDPMIKA_01922 1.31e-116 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MEDPMIKA_01923 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MEDPMIKA_01924 2.37e-222 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
MEDPMIKA_01925 0.0 glgP 2.4.1.1, 2.4.1.11, 2.4.1.8 GH65,GT3,GT35 G ko:K00688,ko:K00691,ko:K16153 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000,ko01003 Protein of unknown function (DUF3417)
MEDPMIKA_01926 0.0 - - - G - - - glycogen debranching enzyme, archaeal type
MEDPMIKA_01927 3.4e-309 - - - G - - - Glycosyl transferase 4-like domain
MEDPMIKA_01928 3.64e-290 amyA 3.2.1.1 GH57 G ko:K07405 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 57 family
MEDPMIKA_01929 1.38e-259 - - - HJ - - - Belongs to the D-alanine--D-alanine ligase family
MEDPMIKA_01930 9.4e-24 - - - K - - - Peptidase_C39 like family
MEDPMIKA_01931 7.06e-71 - - - K - - - HxlR-like helix-turn-helix
MEDPMIKA_01932 2.67e-114 - 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1 PfpI family protein
MEDPMIKA_01933 7.49e-207 - - - K - - - transcriptional regulator (AraC family)
MEDPMIKA_01934 1.98e-179 - - - I - - - Diacylglycerol kinase catalytic domain (presumed)
MEDPMIKA_01935 1.95e-193 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MEDPMIKA_01936 4.43e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MEDPMIKA_01937 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MEDPMIKA_01938 0.0 - - - M - - - Tetratricopeptide repeat protein
MEDPMIKA_01939 3.93e-192 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MEDPMIKA_01941 0.0 ctp 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MEDPMIKA_01942 6.95e-211 ydiY - - - ko:K07283 - ko00000 -
MEDPMIKA_01943 3.12e-188 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MEDPMIKA_01944 3.28e-262 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MEDPMIKA_01945 9.38e-132 trmH 2.1.1.34 - J ko:K00556 - ko00000,ko01000,ko03016 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA
MEDPMIKA_01946 9.75e-195 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MEDPMIKA_01947 1.23e-87 cvpA - - S ko:K03558 - ko00000 Colicin V production protein
MEDPMIKA_01948 4.74e-34 - - - K - - - Helix-turn-helix domain
MEDPMIKA_01950 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MEDPMIKA_01951 6.57e-122 - - - C - - - WbqC-like protein family
MEDPMIKA_01952 0.0 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MEDPMIKA_01953 9.73e-47 - - - - - - - -
MEDPMIKA_01954 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MEDPMIKA_01955 7.09e-181 - - - S - - - Protein of unknown function (DUF3108)
MEDPMIKA_01956 1.9e-87 - - - S ko:K19353 ko00540,map00540 ko00000,ko00001,ko01000,ko01005 Arylsulfatase
MEDPMIKA_01957 1.37e-185 - - - D - - - nuclear chromosome segregation
MEDPMIKA_01958 1.48e-212 - - - E - - - N-terminus of Esterase_SGNH_hydro-type
MEDPMIKA_01959 3.51e-227 glk 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MEDPMIKA_01960 3.3e-199 idsA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MEDPMIKA_01961 4.37e-265 prtC - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase family U32
MEDPMIKA_01962 2.81e-170 - - - S - - - Domain of unknown function (DUF5009)
MEDPMIKA_01964 0.0 - - - EU - - - Peptidase, S9A B C family, catalytic domain protein
MEDPMIKA_01965 4.12e-291 - - - P ko:K08169 - ko00000,ko02000 Major Facilitator
MEDPMIKA_01966 0.0 pepP 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Aminopeptidase P, N-terminal domain
MEDPMIKA_01968 1.76e-131 - - - E - - - COG2755 Lysophospholipase L1 and related
MEDPMIKA_01969 0.0 fusA2 - - J ko:K02355 - ko00000,ko03012,ko03029 Elongation factor G, domain IV
MEDPMIKA_01970 0.0 - - - - - - - -
MEDPMIKA_01971 8.15e-142 - - - M - - - Chaperone of endosialidase
MEDPMIKA_01972 0.0 - - - H - - - TonB-dependent Receptor Plug Domain
MEDPMIKA_01973 3.92e-215 - - - S - - - Domain of unknown function (DUF4249)
MEDPMIKA_01977 3.13e-292 - - - S - - - Tetratricopeptide repeat
MEDPMIKA_01978 1.77e-240 mepM_1 - - M - - - Lysin motif
MEDPMIKA_01979 1.26e-130 - - - S - - - Protein of unknown function (DUF3109)
MEDPMIKA_01980 4.22e-220 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MEDPMIKA_01981 2.26e-162 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MEDPMIKA_01982 7.32e-124 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MEDPMIKA_01983 1.48e-172 - - - S - - - Domain of unknown function (DUF1732)
MEDPMIKA_01984 2.27e-246 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MEDPMIKA_01985 1.44e-194 - 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEDPMIKA_01986 1.34e-297 - - - S - - - Protein of unknown function (DUF1015)
MEDPMIKA_01987 1.05e-32 oorD 1.2.7.3 - C ko:K00176 ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200 br01601,ko00000,ko00001,ko00002,ko01000 4Fe-4S binding domain
MEDPMIKA_01988 9.76e-256 vorB 1.2.7.11, 1.2.7.3 - C ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Pyruvate:ferredoxin oxidoreductase core domain II
MEDPMIKA_01989 3.99e-182 vorA 1.2.7.11, 1.2.7.3 - C ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
MEDPMIKA_01990 1.09e-124 porG 1.2.7.3 - C ko:K00177 ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Pyruvate ferredoxin/flavodoxin oxidoreductase
MEDPMIKA_01991 4.33e-61 - - - - - - - -
MEDPMIKA_01992 5.91e-162 - 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
MEDPMIKA_01993 1.67e-206 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MEDPMIKA_01994 6.47e-285 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MEDPMIKA_01995 0.0 - - - S ko:K07091 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Permease, YjgP YjgQ family
MEDPMIKA_01996 2.09e-165 znuB - - P ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MEDPMIKA_01997 5.03e-290 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 Uncharacterized protein family UPF0004
MEDPMIKA_01998 8.08e-154 - - - - - - - -
MEDPMIKA_01999 1.76e-316 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
MEDPMIKA_02000 4.98e-271 - - - - - - - -
MEDPMIKA_02001 6.62e-81 - - - O - - - NfeD-like C-terminal, partner-binding
MEDPMIKA_02002 8.3e-180 - - - S - - - SigmaW regulon antibacterial
MEDPMIKA_02003 2.31e-160 - 3.1.2.12 CE1 S ko:K01070 ko00680,ko01120,ko01200,map00680,map01120,map01200 ko00000,ko00001,ko01000 esterase
MEDPMIKA_02004 1.13e-172 - - - S - - - CDGSH-type zinc finger. Function unknown.
MEDPMIKA_02005 1.59e-29 - - - S - - - Domain of unknown function (DUF4906)
MEDPMIKA_02006 3.81e-246 - - - EGP - - - Major Facilitator Superfamily
MEDPMIKA_02007 3.73e-158 - - - S - - - Fibrobacter succinogenes major domain (Fib_succ_major)
MEDPMIKA_02008 1.01e-274 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
MEDPMIKA_02009 3.62e-230 metXA 2.3.1.31 - E ko:K00641 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MEDPMIKA_02010 2.67e-290 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 O-acetylhomoserine aminocarboxypropyltransferase cysteine synthase
MEDPMIKA_02012 1.55e-221 - - - S - - - COG NOG06028 non supervised orthologous group
MEDPMIKA_02013 4.56e-107 - - - K - - - Bacterial regulatory proteins, tetR family
MEDPMIKA_02014 2.14e-285 - - - M - - - Efflux transporter, outer membrane factor
MEDPMIKA_02015 0.0 - - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MEDPMIKA_02016 4.49e-214 - - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MEDPMIKA_02017 6.58e-174 thiD 2.7.1.49, 2.7.4.7 - K ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Bacterial regulatory helix-turn-helix proteins, AraC family
MEDPMIKA_02018 2.96e-243 fbaB 4.1.2.13 - G ko:K11645 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes
MEDPMIKA_02019 1.92e-220 ldhA 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 D-isomer specific 2-hydroxyacid dehydrogenase
MEDPMIKA_02020 1.82e-172 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEDPMIKA_02021 1.29e-86 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
MEDPMIKA_02022 0.0 zraR - - T ko:K07713 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 acetoacetate metabolism regulatory protein AtoC K07714
MEDPMIKA_02023 3e-296 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEDPMIKA_02024 8.33e-212 - - - L - - - DNA repair photolyase K01669
MEDPMIKA_02025 4.96e-159 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_02026 2.41e-189 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_02027 8.91e-217 - - - K ko:K18954 - ko00000,ko03000 methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family) K00567
MEDPMIKA_02028 4.99e-28 - - - S - - - aldo-keto reductase (NADP) activity
MEDPMIKA_02029 5.33e-148 - - - K - - - methylphosphotriester-DNA alkyltransferase (AraC XylS family) K00567
MEDPMIKA_02030 9.76e-229 - - - U - - - Relaxase mobilization nuclease domain protein
MEDPMIKA_02031 2.56e-83 - - - S - - - Bacterial mobilisation protein (MobC)
MEDPMIKA_02032 2.43e-146 - - - L - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_02033 8.97e-15 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_02034 4.8e-42 - - - - - - - -
MEDPMIKA_02036 3.69e-123 - - - L - - - AAA domain
MEDPMIKA_02037 1.61e-187 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_02038 1.16e-94 - - - K - - - Fic/DOC family
MEDPMIKA_02039 2.27e-59 - - - U - - - BNR Asp-box repeat protein
MEDPMIKA_02041 1.53e-95 - - - S - - - P-loop ATPase and inactivated
MEDPMIKA_02043 1.49e-222 - - - M - - - PQQ enzyme repeat
MEDPMIKA_02044 2.6e-249 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MEDPMIKA_02045 1.92e-94 ppiB 5.2.1.8 - O ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEDPMIKA_02046 5.46e-189 - - - I - - - Acyltransferase family
MEDPMIKA_02047 1.94e-289 dapL 2.6.1.83 - E ko:K10206,ko:K14261 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
MEDPMIKA_02048 2.15e-145 lrgB - - M - - - LrgB-like family
MEDPMIKA_02049 1.3e-68 - - - S ko:K06518 - ko00000,ko02000 LrgA family
MEDPMIKA_02050 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
MEDPMIKA_02051 1.28e-284 - - - MU ko:K18139,ko:K18300 ko01501,ko02024,map01501,map02024 ko00000,ko00001,ko00002,ko01504,ko02000 Efflux transporter, outer membrane factor
MEDPMIKA_02052 0.0 bpeF - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MEDPMIKA_02053 3.88e-208 - - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MEDPMIKA_02054 1.21e-25 - - - S - - - Histone H1
MEDPMIKA_02055 0.0 - 2.7.8.43 - S ko:K03760,ko:K19353 ko00540,ko01503,map00540,map01503 ko00000,ko00001,ko00002,ko01000,ko01005 Arylsulfatase
MEDPMIKA_02056 3.7e-261 - - - M - - - Surface antigen
MEDPMIKA_02057 4.27e-102 - - - S ko:K07109 - ko00000 Bacterial protein of unknown function (YtfJ_HI0045)
MEDPMIKA_02058 2.01e-59 - - - S ko:K15977 - ko00000 methylamine metabolic process
MEDPMIKA_02059 1.25e-119 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG COG2818 3-methyladenine DNA glycosylase
MEDPMIKA_02060 4.53e-89 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Low molecular weight phosphotyrosine protein phosphatase
MEDPMIKA_02061 6.5e-188 - - - M - - - Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MEDPMIKA_02062 1.67e-162 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 KR domain
MEDPMIKA_02063 1.47e-302 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MEDPMIKA_02064 2.02e-147 - - - S - - - Conserved hypothetical protein (DUF2461)
MEDPMIKA_02065 2.72e-181 - - - E - - - Alpha/beta hydrolase family
MEDPMIKA_02066 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MEDPMIKA_02067 3.07e-168 - 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase family
MEDPMIKA_02068 1.02e-303 dapE - - E - - - Peptidase dimerisation domain
MEDPMIKA_02069 9.5e-69 nlpE - - MP - - - lipoprotein NlpE involved in copper resistance
MEDPMIKA_02070 0.0 glmM 5.4.2.8 - G ko:K01840 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III
MEDPMIKA_02071 9.88e-206 udp 2.4.2.3 - F ko:K00757 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Phosphorylase superfamily
MEDPMIKA_02072 1.6e-250 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MEDPMIKA_02073 1.82e-178 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
MEDPMIKA_02074 0.0 lysM - - EM - - - Lysin motif
MEDPMIKA_02075 4.75e-139 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MEDPMIKA_02076 3.52e-103 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 FAD synthetase
MEDPMIKA_02077 3.34e-89 ybgC - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
MEDPMIKA_02078 8.13e-289 - - - S ko:K06158 - ko00000,ko03012 glycosyl transferase family 2
MEDPMIKA_02079 1.68e-293 - - - CO - - - COG NOG24773 non supervised orthologous group
MEDPMIKA_02080 0.0 htpG - - T ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 histidine kinase DNA gyrase B
MEDPMIKA_02081 6.01e-105 - - - C - - - Nitroreductase family
MEDPMIKA_02082 1.3e-204 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MEDPMIKA_02083 2.19e-67 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MEDPMIKA_02084 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase alpha chain like domain
MEDPMIKA_02087 1.61e-149 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Shikimate dehydrogenase substrate binding domain
MEDPMIKA_02088 5.81e-189 - - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
MEDPMIKA_02089 5.65e-111 speG 2.3.1.57 - J ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 Acetyltransferase (GNAT) domain
MEDPMIKA_02090 7.37e-292 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Winged helix-turn-helix DNA-binding
MEDPMIKA_02091 4.99e-195 fabD 2.3.1.39 - I ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 malonyl CoA-acyl carrier protein transacylase
MEDPMIKA_02092 1.71e-07 - - - N - - - S-layer homology domain
MEDPMIKA_02093 3.27e-164 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MEDPMIKA_02094 8.33e-185 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MEDPMIKA_02095 0.0 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 GlcNAc-PI de-N-acetylase
MEDPMIKA_02096 3.92e-137 - - - T - - - Carbohydrate-binding family 9
MEDPMIKA_02097 8.5e-234 mdsC - - S - - - Phosphotransferase enzyme family
MEDPMIKA_02098 4.81e-40 - - - S - - - Domain of unknown function (DUF5017)
MEDPMIKA_02099 1.77e-59 - - - GM ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_02100 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_02101 0.0 - 4.2.2.20, 4.2.2.21 - M ko:K08961 - ko00000,ko01000 Chondroitin sulfate ABC lyase
MEDPMIKA_02102 2.94e-157 - - - O - - - Glycosyl Hydrolase Family 88
MEDPMIKA_02103 0.0 chonabc 4.2.2.20, 4.2.2.21 - N ko:K08961 - ko00000,ko01000 Chondroitin sulfate ABC lyase
MEDPMIKA_02104 1.83e-221 aslA - - P - - - Arylsulfatase
MEDPMIKA_02105 6.74e-211 - - - M - - - Domain of unknown function (DUF4955)
MEDPMIKA_02106 7.62e-10 - - - S - - - COG NOG38840 non supervised orthologous group
MEDPMIKA_02107 1.61e-205 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase, class I
MEDPMIKA_02108 1.4e-241 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MEDPMIKA_02109 1.31e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetohydroxy acid isomeroreductase, catalytic domain
MEDPMIKA_02110 3.16e-105 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 synthase small subunit
MEDPMIKA_02111 0.0 ilvB 2.2.1.6 - E ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Thiamine pyrophosphate enzyme, central domain
MEDPMIKA_02112 0.0 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Dehydratase family
MEDPMIKA_02113 2.94e-181 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MEDPMIKA_02114 3.18e-283 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
MEDPMIKA_02115 1.22e-240 - - - - - - - -
MEDPMIKA_02117 2.34e-225 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEDPMIKA_02118 2.04e-113 - - - C - - - nitroreductase
MEDPMIKA_02119 3.99e-151 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
MEDPMIKA_02120 0.0 - - - E - - - Transglutaminase-like superfamily
MEDPMIKA_02121 5.72e-316 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
MEDPMIKA_02122 2.92e-72 - - - O - - - Peptidase, S8 S53 family
MEDPMIKA_02125 1.26e-274 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MEDPMIKA_02126 2.38e-96 - - - V - - - Type I restriction enzyme R protein N terminus (HSDR_N)
MEDPMIKA_02127 2.43e-158 - - - KT - - - LytTr DNA-binding domain
MEDPMIKA_02128 1.09e-218 - - - T - - - Histidine kinase
MEDPMIKA_02129 0.0 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
MEDPMIKA_02130 6.96e-133 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MEDPMIKA_02131 1.39e-219 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
MEDPMIKA_02132 7.63e-296 miaB 2.8.4.3 - H ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MEDPMIKA_02134 1.19e-279 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MEDPMIKA_02135 5.15e-88 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MEDPMIKA_02136 2.18e-112 lpxA 2.3.1.129 - M ko:K00677 ko00540,ko01100,ko01503,map00540,map01100,map01503 ko00000,ko00001,ko00002,ko01000,ko01005 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MEDPMIKA_02137 0.0 fabZ 3.5.1.108, 4.2.1.59 - IM ko:K16363 ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01005 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
MEDPMIKA_02138 2.12e-151 - - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MEDPMIKA_02141 3.6e-305 cvrA - - P ko:K11105 - ko00000,ko02000 Sodium/hydrogen exchanger family
MEDPMIKA_02142 8.21e-203 - - - D - - - Psort location
MEDPMIKA_02143 6.11e-233 - - - S - - - Oxidoreductase NAD-binding domain protein
MEDPMIKA_02144 2.13e-15 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MEDPMIKA_02145 0.0 - - - S - - - Tat pathway signal sequence domain protein
MEDPMIKA_02146 1.21e-199 - - - G - - - COG NOG16664 non supervised orthologous group
MEDPMIKA_02147 5.94e-189 - - - G - - - COG COG1082 Sugar phosphate isomerases epimerases
MEDPMIKA_02149 5.36e-247 oorB 1.2.7.11, 1.2.7.3 - C ko:K00175 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 ferredoxin oxidoreductase, subunit beta
MEDPMIKA_02150 0.0 porA 1.2.7.11, 1.2.7.3 - C ko:K00174 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 2-oxoacid acceptor oxidoreductase, alpha subunit
MEDPMIKA_02151 0.0 - - - S - - - ABC transporter, ATP-binding protein
MEDPMIKA_02152 1.1e-180 idnO 1.1.1.69 - IQ ko:K00046 - ko00000,ko01000 Oxidoreductase, short chain dehydrogenase reductase family protein
MEDPMIKA_02153 3.58e-202 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MEDPMIKA_02154 1.01e-150 - - - K - - - Helix-turn-helix domain
MEDPMIKA_02157 0.0 - - - S - - - domain protein
MEDPMIKA_02158 1.61e-223 - - - S - - - 2-nitropropane dioxygenase
MEDPMIKA_02160 5.83e-229 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MEDPMIKA_02161 0.0 - - - S - - - TamB, inner membrane protein subunit of TAM complex
MEDPMIKA_02162 7.41e-151 exbB - - U ko:K03561 - ko00000,ko02000 MotA TolQ ExbB proton channel family
MEDPMIKA_02163 1.71e-81 - - - U ko:K03559 - ko00000,ko02000 Transport energizing protein, ExbD TolR family
MEDPMIKA_02164 7.13e-139 - - - M ko:K03646,ko:K03832 - ko00000,ko02000 energy transducer activity
MEDPMIKA_02165 2.07e-70 - - - S - - - Protein of unknown function (DUF1573)
MEDPMIKA_02166 9.8e-262 mtaD 3.5.4.28, 3.5.4.31 - F ko:K12960 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
MEDPMIKA_02167 5.05e-104 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MEDPMIKA_02168 2.19e-11 - - - S - - - Psort location CytoplasmicMembrane, score
MEDPMIKA_02170 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 1,4-alpha-glucan branching enzyme
MEDPMIKA_02171 8.96e-234 - - - P ko:K03305 - ko00000 POT family
MEDPMIKA_02173 9.11e-102 - - - K - - - Bacterial regulatory proteins, tetR family
MEDPMIKA_02174 4.39e-229 - - - MU - - - outer membrane efflux protein
MEDPMIKA_02175 1.52e-191 - - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MEDPMIKA_02176 0.0 czcA - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MEDPMIKA_02177 2.76e-60 - - - E - - - COG NOG19114 non supervised orthologous group
MEDPMIKA_02178 9.69e-169 lipB 3.1.4.55 - S ko:K06167 ko00440,map00440 ko00000,ko00001,ko01000 Metallo-beta-lactamase superfamily
MEDPMIKA_02179 6.9e-168 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MEDPMIKA_02180 5.33e-216 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEDPMIKA_02181 3.86e-129 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MEDPMIKA_02182 7.96e-139 - - - S - - - phosphatase family
MEDPMIKA_02183 1.35e-234 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MEDPMIKA_02184 5.46e-244 - - - N - - - Lipid A 3-O-deacylase (PagL)
MEDPMIKA_02186 3.68e-277 - - - S - - - Protein of unknown function (DUF1016)
MEDPMIKA_02187 1.43e-136 - - - T - - - COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MEDPMIKA_02188 5.62e-137 - - - T - - - COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MEDPMIKA_02189 2.89e-90 - - - - - - - -
MEDPMIKA_02190 6.78e-99 - - - - - - - -
MEDPMIKA_02191 2.08e-72 - - - S - - - Helix-turn-helix domain
MEDPMIKA_02192 1.04e-160 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_02193 2.54e-215 - - - U - - - Relaxase mobilization nuclease domain protein
MEDPMIKA_02194 1.91e-81 - - - S - - - Bacterial mobilisation protein (MobC)
MEDPMIKA_02195 2.08e-242 - - - L - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_02196 1.92e-263 - - - T - - - COG NOG25714 non supervised orthologous group
MEDPMIKA_02197 1.33e-57 - - - K - - - Helix-turn-helix domain
MEDPMIKA_02198 1.6e-216 - - - - - - - -
MEDPMIKA_02200 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MEDPMIKA_02202 2.31e-285 - - - P - - - TonB-dependent receptor
MEDPMIKA_02203 4.85e-145 - - - M ko:K07001 - ko00000 Phospholipase, patatin family
MEDPMIKA_02204 1.08e-112 - - - J - - - Psort location Cytoplasmic, score
MEDPMIKA_02205 1.47e-15 - 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 5-formyltetrahydrofolate cyclo-ligase family
MEDPMIKA_02206 1.99e-148 sdhC - - S ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 cytochrome B subunit, b558 family
MEDPMIKA_02207 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 Fumarate reductase flavoprotein C-term
MEDPMIKA_02208 3.53e-172 frdB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinate dehydrogenase fumarate reductase
MEDPMIKA_02209 1.73e-90 - - - S - - - Domain of unknown function (DUF4252)
MEDPMIKA_02212 1.14e-106 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MEDPMIKA_02213 1.11e-91 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MEDPMIKA_02214 1.19e-37 - - - KT - - - PspC domain protein
MEDPMIKA_02215 1.34e-73 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator
MEDPMIKA_02216 1.07e-73 - - - KT - - - Putative auto-transporter adhesin, head GIN domain
MEDPMIKA_02217 4.67e-239 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MEDPMIKA_02218 5.55e-220 pfkA 2.7.1.11 - G ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MEDPMIKA_02219 2.98e-223 - - - G - - - pfkB family carbohydrate kinase
MEDPMIKA_02220 1.43e-181 - - - S - - - Glycosyltransferase like family 2
MEDPMIKA_02221 0.0 dsbD 1.8.1.8 - CO ko:K04084 - ko00000,ko01000,ko03110 Disulphide bond corrector protein DsbC
MEDPMIKA_02222 6.88e-189 cysK 2.5.1.47 - E ko:K01738,ko:K12339 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Pyridoxal-phosphate dependent enzyme
MEDPMIKA_02223 7.43e-225 - 3.1.6.1 - P ko:K01130 ko00140,ko00600,map00140,map00600 ko00000,ko00001,ko01000 C-terminal region of aryl-sulfatase
MEDPMIKA_02226 0.0 - - - C - - - Cysteine-rich domain
MEDPMIKA_02227 1.01e-64 - - - C - - - 4Fe-4S dicluster domain
MEDPMIKA_02228 1.58e-219 - 1.8.7.3, 1.8.98.4, 1.8.98.5, 1.8.98.6 - C ko:K03388 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 NAD(P)-binding Rossmann-like domain
MEDPMIKA_02229 7.31e-271 - 1.8.7.3, 1.8.98.4, 1.8.98.5, 1.8.98.6 - C ko:K03389 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Cysteine-rich domain
MEDPMIKA_02230 5.26e-171 - 1.8.7.3, 1.8.98.4, 1.8.98.5, 1.8.98.6 - C ko:K03390 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
MEDPMIKA_02231 8.93e-100 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MEDPMIKA_02232 7.45e-51 yihX 3.1.3.10, 3.1.3.104 - S ko:K07025,ko:K20866,ko:K21063 ko00010,ko00740,ko01100,ko01110,ko01120,map00010,map00740,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Haloacid dehalogenase-like hydrolase
MEDPMIKA_02233 1.04e-214 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MEDPMIKA_02234 2.08e-146 lpxH 3.6.1.54 - S ko:K03269 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01005 Calcineurin-like phosphoesterase
MEDPMIKA_02235 2.02e-226 - - - CO - - - Thioredoxin-like
MEDPMIKA_02236 2.75e-134 - - - S - - - Domain of unknown function (DUF4290)
MEDPMIKA_02237 9e-212 ntrX - - T - - - Sigma-54 interaction domain
MEDPMIKA_02238 5.27e-129 - 3.1.3.18 - G ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 Phosphoglycolate phosphatase
MEDPMIKA_02239 6.86e-312 nhaC - - C ko:K03315 - ko00000,ko02000 Na+/H+ antiporter family
MEDPMIKA_02240 1.46e-33 - - - S - - - Domain of unknown function (DUF4492)
MEDPMIKA_02241 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome bd terminal oxidase subunit I
MEDPMIKA_02242 7.63e-252 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome bd terminal oxidase subunit II
MEDPMIKA_02243 6.08e-198 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MEDPMIKA_02245 2.75e-46 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Belongs to the bacterial histone-like protein family
MEDPMIKA_02246 2.31e-271 aspC2 2.6.1.1, 2.6.1.2, 2.6.1.66 - E ko:K00812,ko:K14260 ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 DegT/DnrJ/EryC1/StrS aminotransferase family
MEDPMIKA_02248 9.64e-272 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_02249 1.21e-292 - - - M ko:K18139,ko:K18300 ko01501,ko02024,map01501,map02024 ko00000,ko00001,ko00002,ko01504,ko02000 Efflux transporter, outer membrane factor lipoprotein, NodT family
MEDPMIKA_02250 0.0 - - - V - - - Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MEDPMIKA_02251 9.5e-255 - - - M ko:K03585 ko01501,ko01503,map01501,map01503 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MEDPMIKA_02252 1.1e-37 - - - S - - - ErfK YbiS YcfS YnhG
MEDPMIKA_02253 0.0 covS - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEDPMIKA_02254 1.61e-205 kdpD 2.7.13.3 - T ko:K07646 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MEDPMIKA_02255 5.92e-134 - - - S - - - non supervised orthologous group
MEDPMIKA_02256 2.19e-94 kdpC 3.6.3.12 - P ko:K01548 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MEDPMIKA_02257 6.11e-317 kdpB 3.6.3.12 - P ko:K01547 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MEDPMIKA_02258 2.81e-18 kdpB 3.6.3.12 - P ko:K01547 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MEDPMIKA_02259 0.0 kdpA 3.6.3.12 - P ko:K01546 ko02020,map02020 ko00000,ko00001,ko01000 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MEDPMIKA_02262 1.89e-271 - - - T ko:K02481 - ko00000,ko02022 acetoacetate metabolism regulatory protein AtoC K07714
MEDPMIKA_02263 6.5e-235 - - - I - - - Acyltransferase family
MEDPMIKA_02264 5.84e-91 epsL - - M ko:K13012 - ko00000,ko01005 Bacterial sugar transferase
MEDPMIKA_02265 1.44e-135 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
MEDPMIKA_02266 5.19e-85 - - - EH - - - D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MEDPMIKA_02267 1.61e-101 - - - G - - - HpcH/HpaI aldolase/citrate lyase family
MEDPMIKA_02268 1.43e-57 - - - C - - - Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
MEDPMIKA_02269 6.87e-32 - - - S - - - Polysaccharide pyruvyl transferase
MEDPMIKA_02270 5.38e-70 - - - M - - - Glycosyltransferase like family 2
MEDPMIKA_02271 3.47e-197 - - - M - - - transferase activity, transferring glycosyl groups
MEDPMIKA_02272 2.12e-114 - - - M - - - Glycosyltransferase Family 4
MEDPMIKA_02273 2.05e-189 - - - S - - - Polysaccharide biosynthesis protein
MEDPMIKA_02274 3.88e-86 - - - S - - - Psort location Cytoplasmic, score
MEDPMIKA_02275 1.16e-78 - - - M - - - transferase activity, transferring glycosyl groups
MEDPMIKA_02276 1.43e-206 gmhB 2.7.7.71 - M ko:K15669 ko00540,map00540 ko00000,ko00001,ko01000 Nucleotidyl transferase
MEDPMIKA_02277 7.27e-285 - - - E - - - Belongs to the DegT DnrJ EryC1 family
MEDPMIKA_02278 2.48e-275 - - - GM - - - Polysaccharide biosynthesis protein
MEDPMIKA_02279 1.38e-20 - - - G - - - Acyltransferase family
MEDPMIKA_02281 7.47e-33 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 UDP-glucose/GDP-mannose dehydrogenase family, central domain
MEDPMIKA_02282 5.43e-47 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 UDP-glucose/GDP-mannose dehydrogenase family, central domain
MEDPMIKA_02283 3.61e-35 - - - S - - - Domain of unknown function (DUF4249)
MEDPMIKA_02284 0.0 - - - H - - - TonB-dependent Receptor Plug Domain
MEDPMIKA_02285 0.0 - - - - - - - -
MEDPMIKA_02287 1.71e-104 - - - S - - - Domain of unknown function, B. Theta Gene description (DUF3872)
MEDPMIKA_02288 1.31e-146 - - - S - - - Conjugative transposon protein TraO
MEDPMIKA_02289 4.57e-213 - - - U - - - Conjugative transposon TraN protein
MEDPMIKA_02290 1.64e-222 traM - - S - - - Conjugative transposon TraM protein
MEDPMIKA_02293 5.07e-143 - - - U - - - Conjugative transposon TraK protein
MEDPMIKA_02294 2.03e-251 - - - S - - - Conjugative transposon TraJ protein
MEDPMIKA_02295 1.18e-125 - - - U - - - Domain of unknown function (DUF4141)
MEDPMIKA_02298 2.91e-41 - - - U - - - Conjugation system ATPase, TraG family
MEDPMIKA_02299 0.0 - - - M - - - TamB, inner membrane protein subunit of TAM complex
MEDPMIKA_02300 0.0 - - - M - - - Surface antigen
MEDPMIKA_02303 1.1e-131 - - - S - - - NADPH-dependent FMN reductase
MEDPMIKA_02305 1.59e-69 - - - - - - - -
MEDPMIKA_02307 3.55e-147 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MEDPMIKA_02308 5.44e-257 lolE_1 - - M ko:K09808 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 MacB-like periplasmic core domain
MEDPMIKA_02309 1.78e-158 ydfG - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MEDPMIKA_02310 7.56e-160 - - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
MEDPMIKA_02311 1.19e-304 - - - E - - - COG COG2755 Lysophospholipase L1 and related esterases
MEDPMIKA_02312 0.0 algI - - M - - - MBOAT, membrane-bound O-acyltransferase family
MEDPMIKA_02313 1.57e-113 ybjG 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
MEDPMIKA_02314 2.46e-163 - - - F ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 DNA/RNA non-specific endonuclease
MEDPMIKA_02315 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MEDPMIKA_02316 1.94e-167 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEDPMIKA_02317 3.61e-112 - 3.1.3.97 - S ko:K07053 - ko00000,ko01000 Domain of unknown function
MEDPMIKA_02318 6.37e-77 nodN - - I - - - MaoC like domain
MEDPMIKA_02319 5.5e-103 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MEDPMIKA_02320 1.14e-230 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEDPMIKA_02321 2.07e-135 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MEDPMIKA_02322 5.87e-86 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MEDPMIKA_02323 5.07e-81 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MEDPMIKA_02324 9.28e-18 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MEDPMIKA_02325 2.82e-44 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MEDPMIKA_02326 2.29e-178 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Metallopeptidase family M24
MEDPMIKA_02327 3.84e-312 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MEDPMIKA_02328 1.16e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
MEDPMIKA_02329 1.04e-37 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein L30
MEDPMIKA_02330 1.76e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MEDPMIKA_02331 7.66e-71 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MEDPMIKA_02332 5.94e-127 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MEDPMIKA_02333 5.8e-83 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MEDPMIKA_02334 1.72e-59 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEDPMIKA_02335 1.94e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MEDPMIKA_02336 1.37e-64 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MEDPMIKA_02337 2.28e-77 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MEDPMIKA_02338 8.96e-51 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MEDPMIKA_02339 8.03e-31 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MEDPMIKA_02340 2.69e-95 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MEDPMIKA_02341 4.75e-160 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MEDPMIKA_02342 7.2e-79 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MEDPMIKA_02343 1.49e-58 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MEDPMIKA_02344 2.39e-188 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MEDPMIKA_02345 6.3e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MEDPMIKA_02346 2.2e-133 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MEDPMIKA_02347 1.24e-137 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MEDPMIKA_02348 1.98e-64 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MEDPMIKA_02349 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MEDPMIKA_02350 1.23e-101 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MEDPMIKA_02351 3.71e-83 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MEDPMIKA_02352 3.89e-44 - - - N - - - domain, Protein
MEDPMIKA_02354 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MEDPMIKA_02355 7.81e-160 - - - I - - - alpha/beta hydrolase fold
MEDPMIKA_02356 2.67e-196 - - - EG ko:K08978 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
MEDPMIKA_02357 4.57e-268 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 diaminopimelate decarboxylase
MEDPMIKA_02358 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MEDPMIKA_02359 0.0 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
MEDPMIKA_02361 4.23e-185 - - - S - - - Domain of unknown function (DUF4886)
MEDPMIKA_02362 0.0 - 3.2.1.25 - G ko:K01192 ko00511,ko04142,map00511,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 2, sugar binding domain protein
MEDPMIKA_02363 8.9e-133 - - - K - - - helix_turn_helix, arabinose operon control protein
MEDPMIKA_02364 1.65e-259 - - - S ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MEDPMIKA_02365 7.33e-192 - 2.4.1.339, 2.4.1.340 GH130 G ko:K20885 - ko00000,ko01000 Pfam:DUF377
MEDPMIKA_02366 0.0 - - - P - - - TonB dependent receptor
MEDPMIKA_02367 8.85e-215 - - - GM ko:K21572 - ko00000,ko02000 Pfam:SusD
MEDPMIKA_02368 4.21e-90 - - - - - - - -
MEDPMIKA_02369 5.33e-217 - - - G - - - Belongs to the glycosyl hydrolase 5 (cellulase A) family
MEDPMIKA_02370 4.78e-233 - - - G - - - Belongs to the glycosyl hydrolase 5 (cellulase A) family
MEDPMIKA_02371 2.46e-173 - 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
MEDPMIKA_02372 0.0 glpK 2.7.1.30 - H ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MEDPMIKA_02373 9.29e-168 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MEDPMIKA_02374 5.57e-91 - - - C - - - Flavodoxin
MEDPMIKA_02375 2.28e-169 - - - K - - - transcriptional regulator (AraC family)
MEDPMIKA_02376 2.38e-289 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MEDPMIKA_02377 1.49e-157 - - - S - - - S1 P1 nuclease
MEDPMIKA_02378 1.66e-217 - - - C ko:K07079 - ko00000 4Fe-4S dicluster domain
MEDPMIKA_02379 0.0 - - - P ko:K02014 - ko00000,ko02000 TonB dependent receptor
MEDPMIKA_02380 7e-75 - - - S - - - Psort location CytoplasmicMembrane, score
MEDPMIKA_02381 8.96e-171 - - - C ko:K07138 - ko00000 Fe-S center protein
MEDPMIKA_02382 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Anaerobic ribonucleoside-triphosphate reductase
MEDPMIKA_02383 3.64e-93 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 anaerobic ribonucleoside-triphosphate reductase activating protein
MEDPMIKA_02384 3.4e-112 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_02386 0.0 - - - P ko:K07085 - ko00000 TrkA C-terminal domain protein
MEDPMIKA_02387 6.19e-208 - - - S - - - PHP domain protein
MEDPMIKA_02388 0.0 eptA 2.7.8.43 - S ko:K03760 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01005 lipid A phosphoethanolamine transferase, associated with polymyxin resistance
MEDPMIKA_02390 1.62e-183 miaA 2.5.1.75 - H ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MEDPMIKA_02391 7.32e-93 - - - S - - - Plasmid pRiA4b ORF-3-like protein
MEDPMIKA_02392 2.09e-186 - - - C - - - acyl-CoA reductase
MEDPMIKA_02393 2.67e-121 - - - S ko:K07078 - ko00000 oxidoreductase related to nitroreductase
MEDPMIKA_02395 9.75e-296 - - - L - - - Arm DNA-binding domain
MEDPMIKA_02396 4.58e-235 - - - O - - - Subtilase family
MEDPMIKA_02397 0.0 - - - E - - - Dipeptidyl peptidase IV (DPP IV) N-terminal region
MEDPMIKA_02398 0.0 - - - P - - - TonB dependent receptor
MEDPMIKA_02399 4.92e-207 - - - G ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_02401 4.66e-49 - - - - - - - -
MEDPMIKA_02402 3.57e-11 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MEDPMIKA_02403 3.47e-137 - - - - - - - -
MEDPMIKA_02404 6.15e-239 - - - U - - - Relaxase mobilization nuclease domain protein
MEDPMIKA_02405 6.97e-14 - - - S - - - Bacterial mobilisation protein (MobC)
MEDPMIKA_02406 1.08e-222 - - - L - - - Toprim-like
MEDPMIKA_02407 1.05e-292 virE2 - - S - - - Virulence-associated protein E
MEDPMIKA_02408 6.82e-66 - - - L - - - Helix-turn-helix domain
MEDPMIKA_02409 6.76e-217 - - - - - - - -
MEDPMIKA_02410 1.09e-251 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
MEDPMIKA_02411 0.0 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_02412 4.43e-183 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_02414 1.74e-241 - - - M - - - OmpA family
MEDPMIKA_02417 0.0 plc 4.6.1.13 - U ko:K01771 ko00562,map00562 ko00000,ko00001,ko01000 Involved in the tonB-independent uptake of proteins
MEDPMIKA_02418 1.18e-148 - - - - - - - -
MEDPMIKA_02419 7.94e-93 - - - H - - - response to peptide
MEDPMIKA_02420 4.23e-152 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
MEDPMIKA_02421 0.0 - - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
MEDPMIKA_02422 2.98e-78 - - - S - - - GtrA-like protein
MEDPMIKA_02423 8.36e-160 dpm1 2.4.1.83 GT2 S ko:K00721 ko00510,ko01100,map00510,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase family 2
MEDPMIKA_02424 2.63e-58 - 2.3.1.183 - K ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MEDPMIKA_02425 0.0 - - - M ko:K07289 - ko00000 protein involved in outer membrane biogenesis
MEDPMIKA_02426 4.77e-183 - - - S - - - Lysine exporter LysO
MEDPMIKA_02427 2.5e-57 - - - K - - - Winged helix DNA-binding domain
MEDPMIKA_02428 2.63e-110 - - - S - - - Psort location CytoplasmicMembrane, score
MEDPMIKA_02429 1.57e-94 - - - S - - - Psort location CytoplasmicMembrane, score
MEDPMIKA_02430 3.52e-40 - - - S - - - 2TM domain
MEDPMIKA_02431 2.79e-22 - - - S ko:K06975 - ko00000 Acetyltransferase
MEDPMIKA_02432 1.7e-220 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 NUDIX domain
MEDPMIKA_02433 1.1e-179 yrbG - - P ko:K07301 - ko00000,ko02000 K -dependent Na Ca exchanger family protein
MEDPMIKA_02434 6.64e-155 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
MEDPMIKA_02437 1.31e-118 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
MEDPMIKA_02438 1.23e-77 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MEDPMIKA_02439 1.62e-201 - - - G ko:K05340 - ko00000,ko02000 COG NOG04879 non supervised orthologous group
MEDPMIKA_02440 1.27e-102 - - - F - - - Inosine-uridine preferring nucleoside hydrolase
MEDPMIKA_02441 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_02442 3.45e-219 - - - S ko:K21572 - ko00000,ko02000 RagB SusD family protein
MEDPMIKA_02443 1.19e-28 - - - S - - - Putative binding domain, N-terminal
MEDPMIKA_02444 8.98e-48 - - - N - - - domain, Protein
MEDPMIKA_02445 2.1e-138 - - - T - - - Lipopolysaccharide kinase (Kdo/WaaP) family
MEDPMIKA_02446 1.34e-177 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
MEDPMIKA_02447 7.77e-239 pheB 5.4.99.5 - E ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase type II
MEDPMIKA_02448 1.4e-138 srrA - - T ko:K07657,ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEDPMIKA_02449 4.49e-290 - 2.7.13.3 - T ko:K02484,ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
MEDPMIKA_02450 0.0 - - - U - - - Psort location CytoplasmicMembrane, score 10.00
MEDPMIKA_02451 8.02e-73 - - - S - - - Psort location CytoplasmicMembrane, score
MEDPMIKA_02452 7.48e-36 - - - S - - - COG NOG31508 non supervised orthologous group
MEDPMIKA_02453 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 9.97
MEDPMIKA_02454 3.57e-160 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEDPMIKA_02455 1.41e-249 - - - S - - - Acyltransferase family
MEDPMIKA_02456 9.91e-291 agcS - - U ko:K03310 - ko00000 Sodium:alanine symporter family
MEDPMIKA_02457 0.0 actP 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 Copper-exporting ATPase
MEDPMIKA_02458 2.04e-88 - - - K - - - Transcriptional regulator, AraC family
MEDPMIKA_02460 0.0 - - - G - - - Belongs to the glycosyl hydrolase 43 family
MEDPMIKA_02461 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MEDPMIKA_02462 2.4e-171 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MEDPMIKA_02463 1.55e-92 - - - - - - - -
MEDPMIKA_02464 5.47e-209 - - - U - - - Relaxase/Mobilisation nuclease domain
MEDPMIKA_02465 1.5e-64 - - - S - - - Bacterial mobilization protein MobC
MEDPMIKA_02466 1.67e-249 - - - L - - - COG NOG08810 non supervised orthologous group
MEDPMIKA_02467 0.0 - - - S - - - COG NOG11635 non supervised orthologous group
MEDPMIKA_02468 4.41e-80 - - - K - - - DNA binding domain, excisionase family
MEDPMIKA_02469 9.93e-267 - - - S - - - Protein of unknown function (DUF3800)
MEDPMIKA_02470 7.02e-261 - - - - - - - -
MEDPMIKA_02471 9.82e-203 - - - S - - - Mobilizable transposon, TnpC family protein
MEDPMIKA_02472 4.73e-265 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_02473 4.84e-82 - - - L - - - DNA binding domain, excisionase family
MEDPMIKA_02474 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Beta galactosidase small chain
MEDPMIKA_02475 6.11e-218 - - - S - - - 37-kD nucleoid-associated bacterial protein
MEDPMIKA_02476 1.77e-69 - - - - - - - -
MEDPMIKA_02477 2.8e-133 - - - S - - - Oxidoreductase, short chain dehydrogenase reductase family
MEDPMIKA_02478 2.1e-102 - - - T - - - COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MEDPMIKA_02479 2.53e-35 - - - - - - - -
MEDPMIKA_02480 3.92e-94 - - - S - - - SNARE-like domain protein
MEDPMIKA_02481 3.09e-97 yvbK 2.3.1.82 - K ko:K03827,ko:K18815 - br01600,ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
MEDPMIKA_02482 2.02e-101 - 1.16.3.2 - P ko:K02217 - ko00000,ko01000 Iron-storage protein
MEDPMIKA_02483 2.8e-79 - - - S - - - Putative beta-lactamase-inhibitor-like, PepSY-like
MEDPMIKA_02484 3.04e-256 - - - T - - - His Kinase A (phospho-acceptor) domain
MEDPMIKA_02485 6.08e-153 - - - T - - - Transcriptional regulatory protein, C terminal
MEDPMIKA_02486 1.74e-115 lpsA - - S - - - Lipopolysaccharide biosynthesis protein
MEDPMIKA_02487 1.2e-227 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MEDPMIKA_02488 4.2e-194 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MEDPMIKA_02489 1.96e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Ribosomal L32p protein family
MEDPMIKA_02490 1.35e-97 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_02492 0.0 - - - P - - - CarboxypepD_reg-like domain
MEDPMIKA_02493 2.67e-82 - - - S - - - Protein of unknown function (DUF4876)
MEDPMIKA_02494 7.1e-136 - - - - - - - -
MEDPMIKA_02495 1.51e-200 - - - C - - - lyase activity
MEDPMIKA_02496 5.09e-207 - - - C - - - HEAT repeats
MEDPMIKA_02497 6.38e-228 - - - C - - - lyase activity
MEDPMIKA_02498 3.39e-92 - - - U - - - Relaxase/Mobilisation nuclease domain
MEDPMIKA_02499 2.07e-73 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MEDPMIKA_02500 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MEDPMIKA_02501 9.52e-165 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MEDPMIKA_02502 2.37e-151 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MEDPMIKA_02503 3.15e-215 - - - S - - - AI-2E family transporter
MEDPMIKA_02504 6.77e-70 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 riboflavin kinase activity
MEDPMIKA_02505 0.0 ahcY 3.3.1.1 - H ko:K01251 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MEDPMIKA_02506 4.08e-08 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MEDPMIKA_02507 2.38e-09 - - - PT - - - Domain of unknown function (DUF4974)
MEDPMIKA_02508 2.95e-255 - - - P - - - TonB-dependent receptor plug
MEDPMIKA_02509 3.47e-14 - - - S - - - Starch-binding associating with outer membrane
MEDPMIKA_02510 4.05e-63 - - - S - - - Endonuclease/Exonuclease/phosphatase family
MEDPMIKA_02511 8.15e-86 - - - - - - - -
MEDPMIKA_02512 7.04e-63 - - - S - - - PFAM Endonuclease Exonuclease phosphatase
MEDPMIKA_02513 0.0 - - - S - - - Belongs to the peptidase M16 family
MEDPMIKA_02514 9.67e-98 - - - S ko:K09793 - ko00000 Protein of unknown function (DUF456)
MEDPMIKA_02515 4.64e-76 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MEDPMIKA_02516 1.44e-173 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MEDPMIKA_02517 0.0 - 3.4.14.4 - S ko:K01277 - ko00000,ko01000,ko01002 Peptidase family M49
MEDPMIKA_02518 3.33e-112 - - - - - - - -
MEDPMIKA_02519 9.55e-66 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor
MEDPMIKA_02520 5.57e-79 - - - PT - - - COG3712 Fe2 -dicitrate sensor, membrane component
MEDPMIKA_02521 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_02522 1.09e-216 - - - H - - - Susd and RagB outer membrane lipoprotein
MEDPMIKA_02524 4.34e-116 - - - S - - - Pentaxin family
MEDPMIKA_02525 4e-17 - - - G - - - Belongs to the glycosyl hydrolase 18 family
MEDPMIKA_02526 4.75e-46 - - - S - - - Pentaxin family
MEDPMIKA_02527 2e-208 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MEDPMIKA_02528 3.78e-169 metN - - Q ko:K02065 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MEDPMIKA_02529 8.03e-153 mlaE - - Q ko:K02066 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Permease MlaE
MEDPMIKA_02531 3.79e-307 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminal
MEDPMIKA_02532 7.1e-258 Dcc - - - - - - -
MEDPMIKA_02534 4.27e-316 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Amino acid permease
MEDPMIKA_02535 0.0 - - - P - - - TonB-dependent receptor
MEDPMIKA_02536 1.1e-158 - - - S ko:K03453 - ko00000 Bile acid
MEDPMIKA_02537 7.43e-65 - - - K ko:K03088 - ko00000,ko03021 RNA polymerase sigma-70 factor, Bacteroides expansion family 1
MEDPMIKA_02538 1.42e-17 - - - PT - - - FecR protein
MEDPMIKA_02539 2.19e-287 - - - H - - - TonB-dependent Receptor Plug Domain
MEDPMIKA_02540 7.28e-145 - - - P ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_02542 4.18e-269 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Alpha galactosidase A
MEDPMIKA_02545 1.58e-160 - - - K - - - Pfam Fic DOC family
MEDPMIKA_02546 5.52e-25 - - - - - - - -
MEDPMIKA_02547 7.46e-262 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_02548 5.99e-69 - - - O - - - Trypsin
MEDPMIKA_02549 1.51e-34 - - - N - - - Flagellar Motor Protein
MEDPMIKA_02550 7.25e-71 - - - N - - - Flagellar Motor Protein
MEDPMIKA_02551 2.02e-52 - - - U - - - peptide transport
MEDPMIKA_02553 5.82e-301 - - - O - - - Heat shock 70 kDa protein
MEDPMIKA_02554 6.16e-133 - - - D - - - Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MEDPMIKA_02555 1.06e-96 - - - - - - - -
MEDPMIKA_02556 0.0 speA 4.1.1.19 - E ko:K01585 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Pyridoxal-dependent decarboxylase, C-terminal sheet domain
MEDPMIKA_02558 3.33e-255 fhlA - - T - - - Bacterial regulatory protein, Fis family
MEDPMIKA_02559 1.1e-98 lptE - - S - - - Lipopolysaccharide-assembly
MEDPMIKA_02560 1.24e-69 - - - - - - - -
MEDPMIKA_02561 6.59e-54 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
MEDPMIKA_02562 0.0 - - - D - - - Psort location
MEDPMIKA_02563 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_02564 0.0 - - - GM ko:K21572 - ko00000,ko02000 SusD family
MEDPMIKA_02565 0.0 - 3.2.1.45 GH30 G ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 30 family
MEDPMIKA_02566 0.0 - - - S - - - Domain of unknown function (DUF5121)
MEDPMIKA_02567 0.0 bglB_4 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3
MEDPMIKA_02568 3.83e-96 - - - J - - - Acetyltransferase (GNAT) domain
MEDPMIKA_02569 9.57e-175 dacA - - S - - - Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MEDPMIKA_02570 5.24e-105 - - - M ko:K06142 - ko00000 unfolded protein binding
MEDPMIKA_02571 1.25e-105 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MEDPMIKA_02574 1.22e-05 - - - O - - - Peptidyl-prolyl cis-trans isomerase
MEDPMIKA_02575 1.3e-50 - - - S - - - COG NOG19094 non supervised orthologous group
MEDPMIKA_02576 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MEDPMIKA_02577 1.44e-61 sugE - - P ko:K11741 - ko00000,ko02000 Multidrug resistance protein, SMR family
MEDPMIKA_02578 1.19e-181 - - - EG - - - EamA-like transporter family
MEDPMIKA_02579 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MEDPMIKA_02580 7.53e-79 - - - - - - - -
MEDPMIKA_02581 1.38e-94 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MEDPMIKA_02582 7.18e-161 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Pterin binding enzyme
MEDPMIKA_02583 1.68e-138 lolD - - V ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner
MEDPMIKA_02584 3.74e-68 aprN - - O - - - Belongs to the peptidase S8 family
MEDPMIKA_02585 2.92e-163 - - - L - - - Protein of unknown function (DUF2400)
MEDPMIKA_02586 8.87e-53 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_02587 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MEDPMIKA_02588 4.08e-290 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Histidyl-tRNA synthetase
MEDPMIKA_02589 0.0 - - - S - - - ATP-binding cassette protein, ChvD family
MEDPMIKA_02590 2.27e-134 rbr - - C - - - Ferritin-like domain
MEDPMIKA_02591 2.09e-211 - - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
MEDPMIKA_02592 7.21e-62 - - - S - - - Domain of unknown function (DUF4491)
MEDPMIKA_02593 2.34e-164 ybdG_2 - - M ko:K16053 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
MEDPMIKA_02594 8.39e-295 - - - S - - - COG NOG10142 non supervised orthologous group
MEDPMIKA_02595 7e-224 - - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
MEDPMIKA_02596 5.99e-206 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Riboflavin biosynthesis protein RibD
MEDPMIKA_02597 1.43e-279 - - - MU - - - Outer membrane efflux protein
MEDPMIKA_02598 1.64e-202 - - - M ko:K01993 - ko00000 Biotin-lipoyl like
MEDPMIKA_02599 1.24e-247 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MEDPMIKA_02600 2.91e-268 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MEDPMIKA_02602 5.47e-17 - - - S - - - Peptidase C10 family
MEDPMIKA_02603 0.0 - - - M - - - Outer membrane protein beta-barrel family
MEDPMIKA_02604 3.04e-50 - - - - - - - -
MEDPMIKA_02605 1.04e-151 - - - KT - - - COG3279 Response regulator of the LytR AlgR family
MEDPMIKA_02606 2.23e-283 - - - T - - - Histidine kinase
MEDPMIKA_02607 2.99e-107 paaY - - S ko:K02617,ko:K08279 - ko00000 Bacterial transferase hexapeptide
MEDPMIKA_02608 4.37e-169 mazG 3.6.1.66 - S ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 MazG nucleotide pyrophosphohydrolase domain
MEDPMIKA_02609 0.0 - 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Glycosyl hydrolase family 20, catalytic domain
MEDPMIKA_02610 2.12e-79 yhhN - - S - - - YhhN family
MEDPMIKA_02611 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEDPMIKA_02612 0.0 trpB 4.2.1.20 - E ko:K06001 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MEDPMIKA_02614 1.15e-32 - - - K - - - transcriptional regulator
MEDPMIKA_02615 0.0 cdr - - P - - - Belongs to the sulfur carrier protein TusA family
MEDPMIKA_02616 3.89e-32 cdr - - P - - - Belongs to the sulfur carrier protein TusA family
MEDPMIKA_02617 5.3e-46 - - - - - - - -
MEDPMIKA_02618 7.56e-169 - - - S - - - COG NOG14441 non supervised orthologous group
MEDPMIKA_02619 3.43e-106 - - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_02620 0.0 - - - O - - - Peptidase, S8 S53 family
MEDPMIKA_02621 0.0 - - - - - - - -
MEDPMIKA_02622 0.0 - - - E ko:K21572 - ko00000,ko02000 COG NOG25454 non supervised orthologous group
MEDPMIKA_02623 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_02627 1.61e-115 - - - S - - - Short repeat of unknown function (DUF308)
MEDPMIKA_02628 1.84e-86 - - - M - - - chlorophyll binding
MEDPMIKA_02630 6.03e-43 - - - M - - - non supervised orthologous group
MEDPMIKA_02631 1.33e-05 - - - - - - - -
MEDPMIKA_02632 8.28e-65 - - - S - - - Protein of unknown function, DUF488
MEDPMIKA_02633 5.19e-12 - - - E - - - Glyoxalase-like domain
MEDPMIKA_02635 1.33e-118 rpoE - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MEDPMIKA_02636 1.81e-174 fieF - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEDPMIKA_02637 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
MEDPMIKA_02638 0.0 - - - I - - - Outer membrane protein transport protein, Ompp1 FadL TodX
MEDPMIKA_02639 3.34e-122 - - - S - - - Psort location OuterMembrane, score
MEDPMIKA_02641 2.48e-227 ltd - - GM - - - NAD dependent epimerase dehydratase family
MEDPMIKA_02642 8.64e-197 - - - S ko:K06889 - ko00000 of the alpha beta superfamily
MEDPMIKA_02643 3.16e-234 fba 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
MEDPMIKA_02644 0.0 fumB 4.2.1.2 - C ko:K01676 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible hydration of fumarate to (S)- malate
MEDPMIKA_02645 0.0 batD - - S - - - Oxygen tolerance
MEDPMIKA_02646 1.35e-158 batE - - T - - - Tetratricopeptide repeat
MEDPMIKA_02647 1.57e-133 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MEDPMIKA_02648 1.55e-229 mdh 1.1.1.37 - C ko:K00024 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the LDH MDH superfamily
MEDPMIKA_02649 5.32e-77 - - - O - - - META domain
MEDPMIKA_02650 6.66e-67 ridA 3.5.99.10 - J ko:K09022 - ko00000,ko01000 Endoribonuclease L-PSP
MEDPMIKA_02651 0.0 nrd 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
MEDPMIKA_02652 2.3e-205 - - - M - - - OmpA family
MEDPMIKA_02654 2.63e-51 - - - S - - - Protein of unknown function (DUF721)
MEDPMIKA_02655 2.01e-231 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MEDPMIKA_02656 2.14e-138 - - - S - - - Tetratricopeptide repeat
MEDPMIKA_02657 9.45e-126 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MEDPMIKA_02658 1.84e-271 - - - C - - - C terminal of Calcineurin-like phosphoesterase
MEDPMIKA_02659 9.84e-299 - - - P ko:K03308 - ko00000 Sodium:neurotransmitter symporter family
MEDPMIKA_02660 4.85e-68 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MEDPMIKA_02661 4.24e-306 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MEDPMIKA_02662 0.0 dnaX 2.7.7.7 - H ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEDPMIKA_02663 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MEDPMIKA_02664 9.73e-222 - - CE1 Q ko:K03932 - ko00000 Esterase PHB depolymerase
MEDPMIKA_02665 7.05e-219 - - - M - - - Glycosyltransferase, group 2 family protein
MEDPMIKA_02666 4.28e-196 - - - - - - - -
MEDPMIKA_02667 3.91e-136 - - - M - - - Cytidylyltransferase
MEDPMIKA_02668 2.66e-204 luxE - - H - - - PFAM Acyl-protein synthetase, LuxE
MEDPMIKA_02669 1.15e-97 - - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MEDPMIKA_02671 1.04e-143 - - - S ko:K07507 - ko00000,ko02000 Mg2 transporter-C family protein
MEDPMIKA_02672 3.42e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MEDPMIKA_02673 2.44e-71 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MEDPMIKA_02675 3.32e-241 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
MEDPMIKA_02677 2e-154 - - - S - - - Beta-lactamase superfamily domain
MEDPMIKA_02678 4.83e-43 - - - S - - - Psort location CytoplasmicMembrane, score 9.46
MEDPMIKA_02679 8.9e-51 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
MEDPMIKA_02681 2.9e-56 - - - P ko:K07213,ko:K08364 ko04978,map04978 ko00000,ko00001,ko02000 mercury ion transmembrane transporter activity
MEDPMIKA_02682 0.0 - - - P - - - receptor
MEDPMIKA_02684 1.4e-36 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
MEDPMIKA_02685 0.0 recQ2 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MEDPMIKA_02686 2.59e-129 rnd - - L - - - 3'-5' exonuclease
MEDPMIKA_02687 6.29e-272 rlmI 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase
MEDPMIKA_02688 1.1e-176 xynZ - - S - - - Putative esterase
MEDPMIKA_02689 5.85e-176 - - - S - - - amine dehydrogenase activity
MEDPMIKA_02690 0.0 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
MEDPMIKA_02691 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MEDPMIKA_02692 0.0 - - - A - - - Domain of Unknown Function (DUF349)
MEDPMIKA_02693 0.0 - 3.6.4.13 - L ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Belongs to the DEAD box helicase family
MEDPMIKA_02694 1.21e-142 - - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEDPMIKA_02695 3.02e-236 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MEDPMIKA_02696 3.28e-244 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MEDPMIKA_02697 1.19e-68 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEDPMIKA_02698 8.14e-98 - - - O - - - Domain of unknown function (DUF4861)
MEDPMIKA_02700 0.0 sufB - - O ko:K09014 - ko00000 Uncharacterized protein family (UPF0051)
MEDPMIKA_02701 9.61e-167 sufC - - O ko:K09013 - ko00000,ko02000 ABC transporter
MEDPMIKA_02702 3.6e-162 sufD - - O ko:K09015 - ko00000 Uncharacterized protein family (UPF0051)
MEDPMIKA_02703 1.54e-271 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MEDPMIKA_02704 3.74e-144 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MEDPMIKA_02705 1.74e-251 doxX - - S - - - DoxX family
MEDPMIKA_02706 1.38e-207 - - - M - - - Biotin-lipoyl like
MEDPMIKA_02707 0.0 - - - V - - - Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MEDPMIKA_02708 8.74e-249 - - - MU - - - Outer membrane efflux protein
MEDPMIKA_02709 1.6e-64 - - - O ko:K07397 - ko00000 OsmC-like protein
MEDPMIKA_02710 0.0 - - - G - - - Tetratricopeptide repeat protein
MEDPMIKA_02711 0.0 - - - H - - - cobalamin-transporting ATPase activity
MEDPMIKA_02712 1.73e-170 - 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MEDPMIKA_02713 5.2e-306 - - - S ko:K07079 - ko00000 Aldo/keto reductase family
MEDPMIKA_02714 2.07e-278 yccM - - C - - - 4Fe-4S binding domain
MEDPMIKA_02715 3.1e-148 yvgN - - S - - - aldo keto reductase family
MEDPMIKA_02716 7.8e-126 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
MEDPMIKA_02717 9.75e-296 - - - L - - - COG4974 Site-specific recombinase XerD
MEDPMIKA_02718 2.28e-71 - - - S - - - COG3943, virulence protein
MEDPMIKA_02719 0.0 - - - S - - - Protein of unknown function (DUF4099)
MEDPMIKA_02720 4.51e-37 - - - - - - - -
MEDPMIKA_02721 0.0 - 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase
MEDPMIKA_02722 3.9e-105 - - - S - - - Domain of unknown function (DUF1896)
MEDPMIKA_02723 0.0 - - - L - - - Helicase conserved C-terminal domain
MEDPMIKA_02724 5.8e-248 - - - S - - - Protein of unknown function (DUF1016)
MEDPMIKA_02725 2.4e-75 - - - S - - - Helix-turn-helix domain
MEDPMIKA_02726 5.83e-67 - - - S - - - Helix-turn-helix domain
MEDPMIKA_02727 6.21e-206 - - - S - - - RteC protein
MEDPMIKA_02728 3.09e-210 - - - K - - - methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family) K00567
MEDPMIKA_02729 2.62e-86 - - - - - - - -
MEDPMIKA_02731 1.43e-112 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Conserved hypothetical protein 95
MEDPMIKA_02733 2.72e-121 - - - S - - - COG NOG19144 non supervised orthologous group
MEDPMIKA_02734 4.11e-309 recD2_2 3.1.11.5 - L ko:K01144 - ko00000,ko01000 PIF1-like helicase
MEDPMIKA_02735 2e-123 mug - - L - - - DNA glycosylase
MEDPMIKA_02736 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MEDPMIKA_02737 8.22e-09 - - - - - - - -
MEDPMIKA_02738 2.7e-138 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MEDPMIKA_02739 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEDPMIKA_02740 6.93e-158 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 ABC transporter, ATP-binding protein
MEDPMIKA_02742 9.63e-40 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_02743 7.28e-210 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_02744 1.89e-294 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_02745 6.98e-33 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_02746 0.0 - - - S - - - Plasmid recombination enzyme
MEDPMIKA_02751 0.0 - - - P - - - TonB-linked outer membrane protein, SusC RagA family
MEDPMIKA_02752 0.0 - - - H - - - Susd and RagB outer membrane lipoprotein
MEDPMIKA_02753 1.5e-211 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_02754 1.22e-37 - - - M - - - Domain of unknown function
MEDPMIKA_02758 0.0 - - - L - - - DNA helicase
MEDPMIKA_02759 9.02e-106 - - - - - - - -
MEDPMIKA_02760 6.65e-160 - - - S - - - Plasmid recombination enzyme
MEDPMIKA_02761 1.31e-96 - - - L - - - Belongs to the 'phage' integrase family
MEDPMIKA_02762 2.15e-294 fadL - - I ko:K06076 - ko00000,ko02000 Outer membrane protein transport protein (OMPP1/FadL/TodX)
MEDPMIKA_02764 1.78e-267 sdaA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase alpha chain
MEDPMIKA_02766 3.94e-85 - - - S - - - Dinitrogenase iron-molybdenum cofactor
MEDPMIKA_02767 5.63e-08 actCD - - C ko:K00185 - ko00000 Cytochrome c
MEDPMIKA_02768 2.37e-224 - - - V - - - FemAB family
MEDPMIKA_02769 1.68e-125 mgtC - - S ko:K07507 - ko00000,ko02000 MgtC family
MEDPMIKA_02770 0.0 ramA_2 - - S - - - Psort location Cytoplasmic, score 8.96
MEDPMIKA_02771 4.2e-268 ampG - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major Facilitator
MEDPMIKA_02772 3.91e-239 - 2.4.1.319, 2.4.1.320 - G ko:K18785 - ko00000,ko01000 cog cog2152
MEDPMIKA_02773 0.0 - - - G - - - Glycosyl hydrolase family 92
MEDPMIKA_02776 1.01e-307 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dihydrolipoyl dehydrogenase
MEDPMIKA_02777 0.0 - - - M - - - Peptidase family C69
MEDPMIKA_02778 9.43e-200 - - - S - - - Domain of unknown function (DUF4784)
MEDPMIKA_02779 5.33e-137 yggS - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MEDPMIKA_02780 1.21e-142 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEDPMIKA_02781 2.34e-100 - - - V - - - HNH endonuclease
MEDPMIKA_02782 3.89e-168 - - - - - - - -
MEDPMIKA_02784 3.5e-11 - - - S - - - Protein of unknown function (DUF3408)
MEDPMIKA_02785 1.33e-178 - - - D - - - COG NOG26689 non supervised orthologous group
MEDPMIKA_02788 5.57e-307 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MEDPMIKA_02789 0.0 - - - G - - - Domain of Unknown Function (DUF1080)
MEDPMIKA_02793 2.79e-311 - - - C - - - Acetyl-CoA hydrolase transferase
MEDPMIKA_02794 9.66e-244 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MEDPMIKA_02796 0.0 katA 1.11.1.6 - C ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 Belongs to the catalase family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)