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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HMCHFCLE_00001	1.77e-160	bcd	1.3.8.1	-	C	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	Acyl-CoA dehydrogenase, C-terminal domain
HMCHFCLE_00002	9.44e-190	-	1.3.1.108	-	C	ko:K03521,ko:K22431	-	ko00000,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_00003	1.51e-259	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HMCHFCLE_00004	7.11e-225	-	-	-	M	-	-	-	Cysteine-rich secretory protein family
HMCHFCLE_00005	4.27e-130	yvyE	-	-	S	-	-	-	YigZ family
HMCHFCLE_00006	8.16e-241	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the dGTPase family. Type 2 subfamily
HMCHFCLE_00007	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMCHFCLE_00008	2.62e-242	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMCHFCLE_00009	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMCHFCLE_00010	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMCHFCLE_00011	3.02e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMCHFCLE_00012	4.66e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMCHFCLE_00013	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMCHFCLE_00014	2.46e-290	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMCHFCLE_00015	9.34e-254	-	2.8.1.7	-	H	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	aminotransferase class V
HMCHFCLE_00016	1.75e-310	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_00017	3.67e-131	rbr3A	-	-	C	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00018	0.0	copA	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
HMCHFCLE_00019	8.96e-79	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
HMCHFCLE_00020	5.07e-188	-	-	-	S	-	-	-	Putative esterase
HMCHFCLE_00021	1.08e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF4250)
HMCHFCLE_00022	1.85e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HMCHFCLE_00023	1.06e-157	-	-	-	S	-	-	-	peptidase M50
HMCHFCLE_00024	4.82e-135	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMCHFCLE_00025	4.64e-124	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMCHFCLE_00026	1.61e-145	-	-	-	-	-	-	-	-
HMCHFCLE_00027	6e-86	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HMCHFCLE_00028	7.39e-188	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HMCHFCLE_00029	3.98e-297	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HMCHFCLE_00030	4.32e-174	-	-	-	K	-	-	-	LytTr DNA-binding domain
HMCHFCLE_00031	1.38e-309	-	-	-	T	-	-	-	Histidine kinase
HMCHFCLE_00032	4.43e-100	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HMCHFCLE_00033	3.13e-224	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HMCHFCLE_00034	5e-174	-	-	-	K	ko:K03710	-	ko00000,ko03000	Psort location Cytoplasmic, score
HMCHFCLE_00035	6.35e-126	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HMCHFCLE_00036	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HMCHFCLE_00037	2.69e-182	thyX	2.1.1.148	-	H	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	ko00000,ko00001,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
HMCHFCLE_00038	6.41e-163	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	thymidylate kinase
HMCHFCLE_00039	5.02e-188	-	-	-	-	-	-	-	-
HMCHFCLE_00040	4.41e-251	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HMCHFCLE_00041	1.71e-305	yhbU_1	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HMCHFCLE_00042	8.26e-110	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00043	2.92e-98	-	-	-	C	-	-	-	Flavodoxin
HMCHFCLE_00044	4.66e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HMCHFCLE_00045	1.78e-146	-	-	-	S	ko:K07025	-	ko00000	IA, variant 3
HMCHFCLE_00046	2.36e-52	-	-	-	S	-	-	-	sporulation protein, YlmC YmxH family
HMCHFCLE_00047	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00048	1.55e-167	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HMCHFCLE_00049	4.01e-208	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMCHFCLE_00050	1.14e-208	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HMCHFCLE_00051	9.36e-269	-	-	-	I	-	-	-	Carboxyl transferase domain
HMCHFCLE_00052	1.09e-33	gcdC	-	-	I	-	-	-	Biotin-requiring enzyme
HMCHFCLE_00053	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Pyruvate carboxylase, C-terminal domain subunit K01960
HMCHFCLE_00054	1.66e-73	-	-	-	S	-	-	-	Helix-turn-helix of DDE superfamily endonuclease
HMCHFCLE_00055	2.05e-198	yicC	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00056	8.5e-55	NPD7_560	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HMCHFCLE_00057	1.04e-129	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HMCHFCLE_00058	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMCHFCLE_00059	1.83e-124	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMCHFCLE_00060	5.13e-215	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMCHFCLE_00061	1.42e-304	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMCHFCLE_00062	4.97e-249	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HMCHFCLE_00063	1.45e-181	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	serine threonine protein phosphatase
HMCHFCLE_00064	0.0	prkC	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HMCHFCLE_00065	4.56e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMCHFCLE_00066	1.35e-149	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HMCHFCLE_00067	0.0	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00068	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMCHFCLE_00069	4.4e-26	spoIIIAA	-	-	S	ko:K06390	-	ko00000	ATPases associated with a variety of cellular activities
HMCHFCLE_00071	1.78e-30	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HMCHFCLE_00073	5.38e-231	spoIIIAE	-	-	S	ko:K06394	-	ko00000	Stage III sporulation protein AE (spore_III_AE)
HMCHFCLE_00075	6.25e-63	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HMCHFCLE_00076	1.51e-119	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
HMCHFCLE_00077	1.29e-74	asp	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HMCHFCLE_00078	9.59e-101	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMCHFCLE_00079	1.4e-166	gcp1	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMCHFCLE_00080	2.32e-208	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMCHFCLE_00081	5.76e-35	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMCHFCLE_00082	1.98e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HMCHFCLE_00083	1.39e-101	-	-	-	S	ko:K09775	-	ko00000	Divergent PAP2 family
HMCHFCLE_00084	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMCHFCLE_00085	1.26e-175	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HMCHFCLE_00086	3.18e-202	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMCHFCLE_00087	6.8e-110	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HMCHFCLE_00088	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HMCHFCLE_00089	9.01e-296	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMCHFCLE_00090	6.51e-128	ptbA	-	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system
HMCHFCLE_00091	1.9e-99	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HMCHFCLE_00092	9.28e-308	capA	-	-	M	ko:K07282	-	ko00000	Capsule synthesis protein
HMCHFCLE_00093	2.6e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMCHFCLE_00094	2.01e-212	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMCHFCLE_00095	1.25e-265	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartate-semialdehyde dehydrogenase family
HMCHFCLE_00096	1.43e-249	queA	2.4.99.17	-	H	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HMCHFCLE_00097	4.55e-290	tgt	2.4.2.29	-	J	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMCHFCLE_00098	5.34e-64	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase, YajC subunit
HMCHFCLE_00100	1.86e-316	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMCHFCLE_00101	8.13e-280	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HMCHFCLE_00102	3.93e-134	-	-	-	M	-	-	-	N-acetylmuramoyl-L-alanine amidase
HMCHFCLE_00103	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMCHFCLE_00104	1.56e-176	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HMCHFCLE_00105	1.09e-199	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMCHFCLE_00106	1.95e-114	ybeY	3.5.4.5	-	S	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMCHFCLE_00107	4.39e-212	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein
HMCHFCLE_00108	6.75e-67	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HMCHFCLE_00109	5.33e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
HMCHFCLE_00111	2.58e-186	-	-	-	S	ko:K07402	-	ko00000	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HMCHFCLE_00112	1.1e-234	-	-	-	O	ko:K07402	-	ko00000	XdhC and CoxI family
HMCHFCLE_00113	1.45e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF3343)
HMCHFCLE_00114	6.1e-210	csd	-	-	E	-	-	-	cysteine desulfurase family protein
HMCHFCLE_00115	1.45e-136	yedF	-	-	O	ko:K04085	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	DsrE/DsrF-like family
HMCHFCLE_00116	1.58e-240	selD	2.7.9.3	-	H	ko:K01008	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000,ko03016	Synthesizes selenophosphate from selenide and ATP
HMCHFCLE_00117	3.97e-162	yqeC	-	-	H	-	-	-	selenium-dependent hydroxylase accessory protein YqeC
HMCHFCLE_00118	0.0	xdhD	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00119	4.49e-112	hcrC	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	[2Fe-2S] binding domain
HMCHFCLE_00120	1.95e-179	-	-	-	C	-	-	-	FAD binding domain in molybdopterin dehydrogenase
HMCHFCLE_00121	6.56e-145	ygfJ	2.7.7.76	-	S	ko:K07141	ko00790,map00790	ko00000,ko00001,ko01000	MobA-like NTP transferase domain
HMCHFCLE_00122	8.75e-36	pbuX	-	-	F	ko:K03458	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_00123	6.77e-72	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HMCHFCLE_00124	0.0	ydcP	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HMCHFCLE_00125	6.48e-99	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HMCHFCLE_00126	5.2e-132	maf	-	-	D	ko:K06287	-	ko00000	Maf-like protein
HMCHFCLE_00127	1.63e-235	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein, MreB Mrl family
HMCHFCLE_00128	4.03e-162	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HMCHFCLE_00129	6.63e-122	-	-	-	S	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HMCHFCLE_00130	0.0	mrdA	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding protein, transpeptidase domain protein
HMCHFCLE_00131	4.06e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HMCHFCLE_00132	3.65e-116	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	sulfurtransferase activity
HMCHFCLE_00133	1.7e-115	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMCHFCLE_00134	0.0	rnj	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMCHFCLE_00135	0.0	yybT	-	-	T	-	-	-	domain protein
HMCHFCLE_00136	1.8e-273	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HMCHFCLE_00137	1.51e-94	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HMCHFCLE_00138	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HMCHFCLE_00139	0.0	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMCHFCLE_00140	1.74e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HMCHFCLE_00141	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMCHFCLE_00142	6.66e-162	-	-	-	-	-	-	-	-
HMCHFCLE_00144	4.15e-233	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Psort location Cytoplasmic, score
HMCHFCLE_00145	9.86e-200	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HMCHFCLE_00146	1.21e-104	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMCHFCLE_00147	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
HMCHFCLE_00148	3.93e-292	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HMCHFCLE_00149	9.71e-310	pdp	2.4.2.2, 2.4.2.4	-	F	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HMCHFCLE_00150	0.0	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	K transport systems, NAD-binding component
HMCHFCLE_00151	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_00152	6.32e-285	-	-	-	S	-	-	-	SPFH domain-Band 7 family
HMCHFCLE_00153	3.84e-257	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HMCHFCLE_00154	2.59e-175	-	-	-	S	ko:K06872	-	ko00000	Pfam:TPM
HMCHFCLE_00155	0.0	clpC	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Belongs to the ClpA ClpB family
HMCHFCLE_00156	5.93e-236	-	-	-	I	-	-	-	Lipid kinase, YegS Rv2252 BmrU family
HMCHFCLE_00157	5.16e-12	-	-	-	I	-	-	-	Acyltransferase
HMCHFCLE_00158	1.62e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMCHFCLE_00159	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMCHFCLE_00160	6.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
HMCHFCLE_00161	6.94e-106	-	-	-	-	-	-	-	-
HMCHFCLE_00162	4.49e-47	-	-	-	K	-	-	-	helix-turn-helix
HMCHFCLE_00163	9.69e-227	-	-	-	L	-	-	-	restriction endonuclease
HMCHFCLE_00164	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
HMCHFCLE_00165	4.81e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
HMCHFCLE_00167	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HMCHFCLE_00168	4.1e-72	-	-	-	L	-	-	-	Virulence-associated protein E
HMCHFCLE_00169	1.77e-185	-	-	-	L	-	-	-	Virulence-associated protein E
HMCHFCLE_00170	6.31e-65	-	-	-	S	-	-	-	Excisionase from transposon Tn916
HMCHFCLE_00171	9.43e-280	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMCHFCLE_00172	0.0	-	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding protein, transpeptidase domain protein
HMCHFCLE_00173	3.16e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HMCHFCLE_00174	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMCHFCLE_00175	7.02e-122	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCHFCLE_00176	0.0	lacZ	3.2.1.23, 3.2.1.31	-	G	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
HMCHFCLE_00177	9.78e-312	lacS	-	-	G	ko:K03292,ko:K11104,ko:K16209	-	ko00000,ko02000	MFS/sugar transport protein
HMCHFCLE_00178	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Melibiase
HMCHFCLE_00179	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMCHFCLE_00180	3.63e-214	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00181	2.38e-310	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family
HMCHFCLE_00184	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_00185	4.49e-196	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_00186	2.31e-195	-	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HMCHFCLE_00187	1.08e-305	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMCHFCLE_00188	8.7e-233	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HMCHFCLE_00189	3.91e-142	-	-	-	F	-	-	-	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMCHFCLE_00190	5.13e-55	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMCHFCLE_00191	8.93e-100	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HMCHFCLE_00192	5.45e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HMCHFCLE_00193	1.09e-271	napA	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_00194	2.97e-211	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HMCHFCLE_00195	1.12e-241	-	-	-	S	-	-	-	Prokaryotic RING finger family 1
HMCHFCLE_00196	3.32e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMCHFCLE_00197	3.26e-294	spoIVB	3.4.21.116	-	S	ko:K06399	-	ko00000,ko01000,ko01002	stage IV sporulation protein B
HMCHFCLE_00198	1.68e-177	spo0A	-	-	K	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HMCHFCLE_00199	0.0	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
HMCHFCLE_00200	6.63e-173	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00201	6.61e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HMCHFCLE_00202	1.04e-117	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMCHFCLE_00203	4e-173	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMCHFCLE_00204	1.44e-195	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_00205	5.41e-274	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HMCHFCLE_00206	9.63e-250	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	Metalloprotease
HMCHFCLE_00207	1.74e-250	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HMCHFCLE_00208	0.0	polC	2.7.7.7	-	L	ko:K02342,ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMCHFCLE_00209	0.0	-	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HMCHFCLE_00210	4.34e-75	-	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HMCHFCLE_00211	1.92e-106	-	-	-	S	-	-	-	CBS domain
HMCHFCLE_00212	0.0	gltA	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HMCHFCLE_00213	3.46e-205	nfnA	1.18.1.2, 1.19.1.1	-	C	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	ko00000,ko00001,ko01000	domain protein
HMCHFCLE_00214	7.2e-166	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
HMCHFCLE_00215	9.93e-208	fba	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HMCHFCLE_00216	1.07e-172	yacO	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMCHFCLE_00217	0.0	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00218	1.22e-282	-	-	-	E	ko:K03310	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_00219	1.72e-315	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HMCHFCLE_00220	6.92e-148	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HMCHFCLE_00221	2.12e-186	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HMCHFCLE_00222	6.18e-115	thiW	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00223	0.0	-	2.4.1.20	GT36	G	ko:K00702	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyltransferase family 36
HMCHFCLE_00224	1.53e-242	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	sugar-binding domain protein
HMCHFCLE_00225	0.0	-	-	-	G	-	-	-	ABC-type sugar transport system periplasmic component
HMCHFCLE_00226	3.83e-231	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCHFCLE_00227	3.79e-192	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_00228	1.58e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HMCHFCLE_00229	1.03e-212	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HMCHFCLE_00230	3.21e-168	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCHFCLE_00231	1.86e-134	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMCHFCLE_00232	1.72e-278	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HMCHFCLE_00233	5.06e-280	-	-	-	-	-	-	-	-
HMCHFCLE_00234	7.15e-95	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HMCHFCLE_00235	8.29e-161	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Universal bacterial protein YeaZ
HMCHFCLE_00236	1.79e-105	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HMCHFCLE_00237	2.42e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMCHFCLE_00238	1.67e-307	-	-	-	V	-	-	-	Polysaccharide biosynthesis C-terminal domain
HMCHFCLE_00239	1.6e-171	-	-	-	E	-	-	-	Pyridoxal-phosphate dependent protein
HMCHFCLE_00240	2.82e-83	-	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMCHFCLE_00241	4.48e-312	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMCHFCLE_00242	2.26e-49	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HMCHFCLE_00243	1.99e-44	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HMCHFCLE_00244	9.81e-129	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMCHFCLE_00245	1e-315	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HMCHFCLE_00246	4.88e-54	ptsH	-	-	G	ko:K11184,ko:K11189	-	ko00000,ko02000	phosphocarrier, HPr family
HMCHFCLE_00247	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMCHFCLE_00248	1.81e-188	-	-	-	U	-	-	-	Protein of unknown function (DUF1700)
HMCHFCLE_00249	4.06e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
HMCHFCLE_00250	3.01e-187	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Amino acid ABC transporter substrate-binding protein, PAAT family (TC 3.A.1.3.-)
HMCHFCLE_00251	5.62e-183	tcyN	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Amino acid ABC transporter ATP-binding protein, PAAT family
HMCHFCLE_00252	1.87e-148	-	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	amino acid ABC transporter
HMCHFCLE_00253	5.48e-206	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HMCHFCLE_00254	9.48e-195	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00255	1.89e-294	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Major Facilitator
HMCHFCLE_00256	6.31e-310	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine
HMCHFCLE_00258	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMCHFCLE_00259	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HMCHFCLE_00260	1.31e-306	leuC	4.2.1.33, 4.2.1.35, 4.2.1.85	-	E	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMCHFCLE_00261	7.69e-115	leuD	4.2.1.33, 4.2.1.35, 4.2.1.85	-	E	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMCHFCLE_00262	4.52e-262	leuB	1.1.1.85	-	C	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HMCHFCLE_00263	1.42e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC-type polar amino acid transport system ATPase component
HMCHFCLE_00264	3.35e-169	ArtM	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	acid ABC transporter
HMCHFCLE_00265	4.24e-168	artP	-	-	ET	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HMCHFCLE_00266	1.94e-130	-	-	-	C	-	-	-	Nitroreductase family
HMCHFCLE_00268	2.33e-93	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HMCHFCLE_00269	8.63e-181	-	-	-	S	-	-	-	Putative threonine/serine exporter
HMCHFCLE_00270	2.25e-192	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HMCHFCLE_00271	1.21e-208	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMCHFCLE_00272	2.37e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type metal ion transport system permease component
HMCHFCLE_00273	1.96e-315	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine aminocarboxypropyltransferase cysteine synthase
HMCHFCLE_00274	2.71e-233	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HMCHFCLE_00275	9.99e-214	-	-	-	S	-	-	-	EDD domain protein, DegV family
HMCHFCLE_00276	1.47e-125	trmL	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMCHFCLE_00277	1.23e-160	-	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Pyridoxal kinase
HMCHFCLE_00280	0.0	-	-	-	C	-	-	-	4Fe-4S binding domain protein
HMCHFCLE_00281	2.89e-316	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	tRNA methylthiotransferase YqeV
HMCHFCLE_00282	1.65e-284	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HMCHFCLE_00283	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HMCHFCLE_00284	5.13e-87	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00285	8.53e-120	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HMCHFCLE_00286	8.45e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HMCHFCLE_00287	0.0	-	-	-	C	-	-	-	FeS-containing Cyanobacterial-specific oxidoreductase
HMCHFCLE_00288	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HMCHFCLE_00289	6.84e-147	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMCHFCLE_00290	4.66e-117	-	-	-	S	-	-	-	Psort location
HMCHFCLE_00291	2.95e-219	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	PBP superfamily domain
HMCHFCLE_00293	2.7e-316	-	-	-	V	-	-	-	MatE
HMCHFCLE_00294	4.87e-114	-	-	-	G	-	-	-	Ricin-type beta-trefoil
HMCHFCLE_00295	2.67e-196	-	-	-	-	-	-	-	-
HMCHFCLE_00297	7.07e-250	lldD	-	-	C	-	-	-	FMN-dependent dehydrogenase
HMCHFCLE_00298	2.35e-216	rluC	5.4.99.24	-	J	ko:K06179	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HMCHFCLE_00299	1.79e-133	-	-	-	-	-	-	-	-
HMCHFCLE_00300	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMCHFCLE_00301	3.67e-71	hinT	-	-	FG	ko:K02503	-	ko00000,ko04147	Psort location Cytoplasmic, score
HMCHFCLE_00302	6.61e-123	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Psort location Cytoplasmic, score
HMCHFCLE_00303	0.0	-	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Psort location CytoplasmicMembrane, score
HMCHFCLE_00304	2.82e-237	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Psort location Cytoplasmic, score
HMCHFCLE_00305	6.2e-140	rnmV	3.1.26.8	-	L	ko:K05985	-	ko00000,ko01000	Ribonuclease M5
HMCHFCLE_00306	1.85e-75	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HMCHFCLE_00307	1.2e-70	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HMCHFCLE_00308	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HMCHFCLE_00309	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HMCHFCLE_00310	0.0	-	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	PASTA domain protein
HMCHFCLE_00311	2.33e-300	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00312	1.57e-118	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
HMCHFCLE_00313	3.65e-235	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
HMCHFCLE_00314	4.99e-171	-	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HMCHFCLE_00315	2.18e-178	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HMCHFCLE_00316	0.0	-	-	-	T	-	-	-	Histidine kinase
HMCHFCLE_00317	2.32e-126	-	-	-	-	-	-	-	-
HMCHFCLE_00318	0.0	-	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase
HMCHFCLE_00319	1.64e-293	uxuA	4.2.1.8	-	H	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HMCHFCLE_00321	0.0	dsdA	4.3.1.18	-	H	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HMCHFCLE_00322	2.71e-51	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HMCHFCLE_00323	6.15e-57	-	-	-	S	-	-	-	YoeB-like toxin of bacterial type II toxin-antitoxin system
HMCHFCLE_00324	3.38e-169	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HMCHFCLE_00325	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family
HMCHFCLE_00327	4.57e-90	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMCHFCLE_00328	1.27e-315	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMCHFCLE_00329	8.65e-53	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HMCHFCLE_00330	1.25e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HMCHFCLE_00331	6.05e-250	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMCHFCLE_00332	0.0	ymfH	-	-	S	-	-	-	Peptidase M16 inactive domain
HMCHFCLE_00333	6.05e-268	-	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HMCHFCLE_00334	7.39e-187	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	serine-type D-Ala-D-Ala carboxypeptidase
HMCHFCLE_00335	1.24e-278	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HMCHFCLE_00336	3.74e-210	thrB	2.7.1.39	-	H	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMCHFCLE_00337	2.41e-298	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HMCHFCLE_00338	7.82e-87	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HMCHFCLE_00339	0.0	-	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HMCHFCLE_00341	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Na Pi-cotransporter II-like protein
HMCHFCLE_00343	5.9e-152	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HMCHFCLE_00344	8.45e-218	-	-	-	P	ko:K03324	-	ko00000,ko02000	Na Pi-cotransporter
HMCHFCLE_00345	4.43e-05	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HMCHFCLE_00346	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC-type multidrug transport system ATPase and permease
HMCHFCLE_00347	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC-type multidrug transport system ATPase and permease
HMCHFCLE_00348	1.43e-222	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00349	0.0	-	-	-	C	-	-	-	domain protein
HMCHFCLE_00350	3.77e-217	-	-	-	S	-	-	-	ATPase family associated with various cellular activities (AAA)
HMCHFCLE_00351	0.0	-	-	-	P	-	-	-	von Willebrand factor (vWF) type A domain
HMCHFCLE_00353	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type oligopeptide transport system periplasmic component
HMCHFCLE_00354	2.35e-244	appF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HMCHFCLE_00355	1.53e-241	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HMCHFCLE_00356	4.86e-237	oppC	-	-	P	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMCHFCLE_00357	4.11e-200	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMCHFCLE_00358	3.66e-125	-	-	-	-	-	-	-	-
HMCHFCLE_00359	8.7e-179	-	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	capsular polysaccharide biosynthesis protein
HMCHFCLE_00360	2.35e-151	-	-	-	D	-	-	-	Capsular exopolysaccharide family
HMCHFCLE_00361	2.15e-147	-	-	-	M	-	-	-	Chain length determinant protein
HMCHFCLE_00362	7.42e-203	-	-	-	P	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HMCHFCLE_00363	2.13e-258	-	-	-	P	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HMCHFCLE_00364	0.0	-	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	transport systems ATPase components
HMCHFCLE_00365	3.04e-260	tmpC	-	-	S	ko:K07335	-	ko00000	basic membrane
HMCHFCLE_00366	1.07e-98	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HMCHFCLE_00367	2.49e-168	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	purine-nucleoside phosphorylase
HMCHFCLE_00368	9.83e-304	-	-	-	D	-	-	-	G5
HMCHFCLE_00369	2.99e-217	rluD_2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HMCHFCLE_00370	0.0	-	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HMCHFCLE_00371	9.81e-77	-	-	-	S	-	-	-	NusG domain II
HMCHFCLE_00372	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HMCHFCLE_00374	6e-105	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00375	6.54e-157	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMCHFCLE_00376	1.32e-171	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMCHFCLE_00377	1.24e-47	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	sporulation transcriptional regulator SpoIIID
HMCHFCLE_00378	1.32e-131	-	-	-	S	ko:K16789	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HMCHFCLE_00380	5.93e-304	nspC	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	carboxynorspermidine decarboxylase
HMCHFCLE_00381	2.27e-307	LYS1	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Saccharopine dehydrogenase
HMCHFCLE_00382	3.77e-214	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HMCHFCLE_00383	2.36e-214	speE	2.5.1.16	-	H	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HMCHFCLE_00384	0.0	speA	4.1.1.19	-	E	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Orn Lys Arg decarboxylase major
HMCHFCLE_00385	1.65e-173	-	-	-	T	-	-	-	response regulator
HMCHFCLE_00386	1.67e-209	-	-	-	T	-	-	-	GHKL domain
HMCHFCLE_00388	3.26e-106	-	-	-	G	-	-	-	Domain of unknown function (DUF386)
HMCHFCLE_00390	2.32e-300	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HMCHFCLE_00391	1.55e-292	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HMCHFCLE_00392	2.5e-235	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HMCHFCLE_00394	1.09e-28	-	-	-	S	-	-	-	ABC-2 family transporter protein
HMCHFCLE_00395	2.31e-194	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMCHFCLE_00396	3.81e-151	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Belongs to the sigma-70 factor family
HMCHFCLE_00397	3.93e-99	spoIIAB	2.7.11.1	-	T	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HMCHFCLE_00398	3.31e-68	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HMCHFCLE_00399	8.19e-286	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydrofolate synthase activity
HMCHFCLE_00400	6.75e-66	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00401	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMCHFCLE_00402	5.79e-248	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HMCHFCLE_00403	0.0	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00404	2.15e-62	-	-	-	M	-	-	-	group 2 family protein
HMCHFCLE_00405	0.0	-	1.5.1.20, 2.1.1.10	-	H	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	homocysteine S-methyltransferase
HMCHFCLE_00406	3.22e-157	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HMCHFCLE_00407	1.3e-282	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMCHFCLE_00408	1.32e-97	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator, AsnC family
HMCHFCLE_00409	1.17e-119	-	-	-	S	-	-	-	Domain of unknown function (DUF4358)
HMCHFCLE_00410	8.34e-66	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00411	4.21e-134	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HMCHFCLE_00412	3.26e-63	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HMCHFCLE_00413	4.56e-243	-	-	-	M	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HMCHFCLE_00414	1.76e-188	-	-	-	-	-	-	-	-
HMCHFCLE_00415	2.64e-79	-	-	-	P	-	-	-	Belongs to the ArsC family
HMCHFCLE_00416	7.31e-38	-	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
HMCHFCLE_00417	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMCHFCLE_00418	9.48e-237	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMCHFCLE_00419	3.04e-176	-	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Nitroreductase family
HMCHFCLE_00420	5.83e-197	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMCHFCLE_00421	0.0	tetP	-	-	J	-	-	-	elongation factor G
HMCHFCLE_00422	1.38e-218	-	-	-	O	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00423	0.0	-	-	-	I	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00424	0.0	hgdC2	-	-	I	-	-	-	CoA-substrate-specific enzyme activase
HMCHFCLE_00425	1.29e-184	-	-	-	S	-	-	-	TraX protein
HMCHFCLE_00427	1.56e-144	-	-	-	-	-	-	-	-
HMCHFCLE_00429	4.28e-225	-	-	-	K	-	-	-	AraC-like ligand binding domain
HMCHFCLE_00430	4.19e-198	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
HMCHFCLE_00431	5.88e-164	-	-	-	K	ko:K22293	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
HMCHFCLE_00433	3.03e-47	-	-	-	S	-	-	-	Putative cell wall binding repeat
HMCHFCLE_00435	3.89e-69	-	-	-	-	-	-	-	-
HMCHFCLE_00436	5.97e-132	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
HMCHFCLE_00437	0.0	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HMCHFCLE_00438	0.0	-	-	-	M	-	-	-	Gram-positive pilin backbone subunit 2, Cna-B-like domain
HMCHFCLE_00439	4.65e-194	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HMCHFCLE_00440	2.64e-142	-	-	-	S	-	-	-	domain, Protein
HMCHFCLE_00441	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HMCHFCLE_00442	7.38e-50	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMCHFCLE_00443	7.99e-189	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
HMCHFCLE_00444	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMCHFCLE_00445	9.45e-302	-	-	-	E	-	-	-	Peptidase dimerisation domain
HMCHFCLE_00446	3.75e-122	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Glycerol-3-phosphate responsive antiterminator
HMCHFCLE_00447	0.0	glpA	1.1.5.3	-	C	ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HMCHFCLE_00448	1.1e-297	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00449	4.52e-81	-	-	-	S	-	-	-	protein with conserved CXXC pairs
HMCHFCLE_00450	1.3e-241	modC	3.6.3.29	-	E	ko:K02017	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HMCHFCLE_00451	4.11e-150	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Molybdate ABC transporter
HMCHFCLE_00452	7.31e-177	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, periplasmic molybdate-binding protein
HMCHFCLE_00453	1.01e-223	mog	-	-	H	-	-	-	Molybdenum cofactor synthesis domain protein
HMCHFCLE_00454	1.39e-233	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HMCHFCLE_00455	7.3e-111	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HMCHFCLE_00456	1.09e-253	moeA2	-	-	H	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00457	4.98e-101	mobB	2.7.7.77	-	H	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Molybdopterin-guanine dinucleotide biosynthesis protein
HMCHFCLE_00458	9.73e-294	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA C-terminal region (domain IV)
HMCHFCLE_00459	8.65e-202	-	-	-	-	-	-	-	-
HMCHFCLE_00460	0.0	-	1.2.7.5	-	C	ko:K03738,ko:K19515	ko00030,ko00362,ko01100,ko01120,ko01200,map00030,map00362,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Aldehyde ferredoxin oxidoreductase, N-terminal domain
HMCHFCLE_00461	5.45e-146	-	-	-	C	-	-	-	4Fe-4S binding domain
HMCHFCLE_00463	1.38e-178	fdhD	-	-	C	ko:K02379	-	ko00000	FdhD/NarQ family
HMCHFCLE_00464	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HMCHFCLE_00465	0.0	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HMCHFCLE_00466	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00467	0.0	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system
HMCHFCLE_00468	8.43e-207	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HMCHFCLE_00469	8.9e-168	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	COG COG1349 Transcriptional regulators of sugar metabolism
HMCHFCLE_00470	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HMCHFCLE_00471	1.03e-223	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	Menaquinone biosynthesis
HMCHFCLE_00472	1.48e-149	-	-	-	K	-	-	-	Cyclic nucleotide-monophosphate binding domain
HMCHFCLE_00473	1.91e-236	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
HMCHFCLE_00474	1.37e-141	-	-	-	S	-	-	-	Flavin reductase-like protein
HMCHFCLE_00475	7.7e-111	queT	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00476	5.71e-158	-	-	-	S	-	-	-	HAD-hyrolase-like
HMCHFCLE_00479	3.57e-260	pfkA	2.7.1.11, 2.7.1.90	-	H	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMCHFCLE_00480	4.69e-302	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HMCHFCLE_00481	0.0	-	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_00483	2.38e-109	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMCHFCLE_00484	5.97e-138	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMCHFCLE_00485	4.97e-70	-	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMCHFCLE_00486	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMCHFCLE_00487	8.74e-236	pta	2.3.1.8	-	C	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	PFAM Phosphate acetyl butaryl transferase
HMCHFCLE_00488	4.43e-140	udgA	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HMCHFCLE_00489	1.98e-258	-	-	-	LO	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00490	0.0	dinG	3.1.12.1, 3.6.4.12	-	L	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	HELICc2
HMCHFCLE_00491	7.22e-114	btuR	2.5.1.17	-	H	ko:K19221	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	cob(I)yrinic acid a,c-diamide adenosyltransferase
HMCHFCLE_00492	1.03e-302	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMCHFCLE_00493	2.95e-120	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMCHFCLE_00494	1.08e-130	fchA	-	-	E	-	-	-	Formiminotransferase-cyclodeaminase
HMCHFCLE_00495	5.03e-196	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMCHFCLE_00496	3.36e-221	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Glycosyl transferase family 4
HMCHFCLE_00497	0.0	-	-	-	V	-	-	-	MATE efflux family protein
HMCHFCLE_00498	9.13e-133	ribU	-	-	S	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMCHFCLE_00499	1.33e-236	-	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HMCHFCLE_00500	2.68e-257	-	-	-	G	-	-	-	Major Facilitator
HMCHFCLE_00501	6.29e-83	-	-	-	S	-	-	-	Putative esterase
HMCHFCLE_00502	0.0	-	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Beta-lactamase class C
HMCHFCLE_00503	5.09e-85	-	-	-	S	-	-	-	Bacterial PH domain
HMCHFCLE_00506	0.0	-	-	-	J	ko:K07576	-	ko00000	Metallo-beta-lactamase domain protein
HMCHFCLE_00507	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HMCHFCLE_00509	0.0	-	-	-	V	ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin transporter
HMCHFCLE_00510	5.3e-104	-	-	-	KT	-	-	-	Transcriptional regulator
HMCHFCLE_00511	8.44e-244	-	-	-	M	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	HlyD family secretion protein
HMCHFCLE_00512	0.0	-	-	-	N	-	-	-	Bacterial Ig-like domain 2
HMCHFCLE_00513	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMCHFCLE_00514	3.91e-118	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00515	2.62e-204	-	-	-	-	-	-	-	-
HMCHFCLE_00516	4.07e-288	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HMCHFCLE_00517	2.23e-90	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	S1 RNA binding domain
HMCHFCLE_00518	4.49e-61	-	-	-	D	ko:K13052	-	ko00000,ko03036	septum formation initiator
HMCHFCLE_00519	8.26e-95	-	-	-	-	-	-	-	-
HMCHFCLE_00520	1.62e-08	yabP	-	-	S	-	-	-	Sporulation protein YabP
HMCHFCLE_00521	2.34e-47	hslR	-	-	J	-	-	-	S4 domain protein
HMCHFCLE_00522	7.71e-52	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMCHFCLE_00523	7.86e-119	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	MazG family
HMCHFCLE_00524	7.52e-72	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HMCHFCLE_00525	5.18e-222	-	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphoribulokinase uridine kinase family
HMCHFCLE_00526	0.0	hemZ	-	-	C	-	-	-	Coproporphyrinogen dehydrogenase
HMCHFCLE_00527	5.98e-150	-	-	-	S	-	-	-	Metallo-beta-lactamase domain protein
HMCHFCLE_00528	9.11e-106	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMCHFCLE_00529	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMCHFCLE_00530	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	exonuclease
HMCHFCLE_00531	6.43e-291	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HMCHFCLE_00532	0.0	-	-	-	S	ko:K07137	-	ko00000	FAD dependent oxidoreductase
HMCHFCLE_00533	4.54e-301	-	-	-	S	-	-	-	YbbR-like protein
HMCHFCLE_00534	1.11e-206	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMCHFCLE_00535	1.27e-270	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HMCHFCLE_00536	0.0	pgcA	5.4.2.2, 5.4.2.8	-	G	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HMCHFCLE_00538	0.0	comM	-	-	O	ko:K07391	-	ko00000	chelatase subunit ChlI
HMCHFCLE_00539	8.93e-309	-	-	-	Q	-	-	-	Amidohydrolase family
HMCHFCLE_00540	4.49e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMCHFCLE_00541	1.77e-201	araC_2	-	-	K	ko:K02099	-	ko00000,ko03000	transcriptional regulator AraC family
HMCHFCLE_00542	5.05e-315	-	-	-	G	ko:K03292	-	ko00000	Transporter, major facilitator family protein
HMCHFCLE_00543	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HMCHFCLE_00544	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
HMCHFCLE_00545	1.61e-32	-	-	-	-	-	-	-	-
HMCHFCLE_00546	6.41e-205	-	-	-	P	ko:K10202	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_00547	1.76e-200	-	-	-	P	ko:K10201	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_00548	1.37e-60	-	-	-	G	ko:K10200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Carbohydrate ABC transporter
HMCHFCLE_00549	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00550	6.88e-257	-	-	-	S	-	-	-	Leucine rich repeats (6 copies)
HMCHFCLE_00551	0.0	-	-	-	S	-	-	-	VWA-like domain (DUF2201)
HMCHFCLE_00552	0.0	-	-	-	S	-	-	-	AAA domain (dynein-related subfamily)
HMCHFCLE_00553	1.6e-103	nifU	-	-	C	ko:K04488	-	ko00000	Fe-S iron-sulfur cluster assembly protein, NifU family
HMCHFCLE_00554	1.75e-297	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins
HMCHFCLE_00555	6.81e-111	-	-	-	-	-	-	-	-
HMCHFCLE_00556	3.71e-74	-	-	-	P	-	-	-	Psort location Cytoplasmic, score 8.96
HMCHFCLE_00557	1.34e-109	-	-	-	K	-	-	-	Transcriptional regulator
HMCHFCLE_00561	3.3e-302	adh	-	-	C	-	-	-	belongs to the iron- containing alcohol dehydrogenase family
HMCHFCLE_00562	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HMCHFCLE_00563	9.44e-183	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMCHFCLE_00564	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	TIGRFAM formate acetyltransferase
HMCHFCLE_00566	3.06e-238	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMCHFCLE_00567	0.0	-	-	-	M	-	-	-	Glycosyl-transferase family 4
HMCHFCLE_00569	1.05e-274	-	-	-	G	-	-	-	Acyltransferase family
HMCHFCLE_00570	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Psort location Cytoplasmic, score
HMCHFCLE_00571	8e-42	-	-	-	IQ	ko:K02078	-	ko00000,ko00001	Acyl carrier protein
HMCHFCLE_00572	2.06e-280	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
HMCHFCLE_00573	4.08e-251	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HMCHFCLE_00574	1.12e-150	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HMCHFCLE_00575	7.13e-39	ynzC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF896)
HMCHFCLE_00576	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMCHFCLE_00577	3.5e-219	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HMCHFCLE_00578	7.36e-251	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate-ammonia ligase
HMCHFCLE_00579	5.4e-162	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HMCHFCLE_00580	4.52e-200	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type branched-chain amino acid transport systems ATPase component
HMCHFCLE_00581	1.43e-230	livM	-	-	E	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HMCHFCLE_00582	3.12e-193	livH	-	-	E	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HMCHFCLE_00583	2.2e-258	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type branched-chain amino acid transport systems periplasmic component
HMCHFCLE_00584	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00585	7.29e-304	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMCHFCLE_00587	0.0	-	-	-	T	ko:K07814	-	ko00000,ko02022	Response regulator containing a CheY-like receiver domain and an HD-GYP domain
HMCHFCLE_00588	6.44e-129	fliY1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HMCHFCLE_00589	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HMCHFCLE_00590	7.21e-169	spoVFA	-	-	EH	ko:K06410	-	ko00000	dipicolinic acid synthetase, A subunit
HMCHFCLE_00591	5.29e-131	spoVFB	-	-	H	ko:K06411	-	ko00000	Dipicolinic acid synthetase, B subunit
HMCHFCLE_00592	1.55e-308	dacB_3	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HMCHFCLE_00593	7.45e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HMCHFCLE_00594	5.05e-189	pyrL	-	-	GM	ko:K01992,ko:K09690	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HMCHFCLE_00595	5.44e-176	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HMCHFCLE_00596	0.0	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase, group 2 family protein
HMCHFCLE_00597	1.91e-135	KatE	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00599	3.37e-311	rnfC	-	-	C	ko:K03615	-	ko00000	Part of a membrane complex involved in electron transport
HMCHFCLE_00600	1.53e-218	rnfD	-	-	C	ko:K03614	-	ko00000	Part of a membrane complex involved in electron transport
HMCHFCLE_00601	6.26e-119	rnfG	-	-	C	ko:K03612	-	ko00000	Part of a membrane complex involved in electron transport
HMCHFCLE_00602	1.23e-150	rnfE	-	-	C	ko:K03613	-	ko00000	Part of a membrane complex involved in electron transport
HMCHFCLE_00603	6.86e-138	rnfA	-	-	C	ko:K03617	-	ko00000	Part of a membrane complex involved in electron transport
HMCHFCLE_00604	5.34e-193	rnfB	-	-	C	ko:K03616	-	ko00000	electron transport complex, RnfABCDGE type, B subunit
HMCHFCLE_00605	2.22e-184	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMCHFCLE_00606	6.95e-122	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HMCHFCLE_00607	1.15e-120	-	-	-	-	-	-	-	-
HMCHFCLE_00608	7.08e-166	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00609	2.71e-198	-	-	-	S	-	-	-	Psort location
HMCHFCLE_00612	0.0	pz-A	-	-	E	-	-	-	Peptidase family M3
HMCHFCLE_00613	2.59e-102	-	-	-	S	-	-	-	Pfam:DUF3816
HMCHFCLE_00614	2.64e-304	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HMCHFCLE_00615	1.98e-98	-	-	-	-	-	-	-	-
HMCHFCLE_00617	1.17e-220	-	-	-	GK	-	-	-	ROK family
HMCHFCLE_00618	3.38e-268	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMCHFCLE_00619	1.68e-132	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_00620	3.51e-134	-	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Pseudouridine synthase
HMCHFCLE_00621	1.1e-161	-	-	-	K	ko:K22293	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
HMCHFCLE_00622	1.99e-124	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HMCHFCLE_00623	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMCHFCLE_00624	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMCHFCLE_00625	1.47e-54	-	-	-	S	-	-	-	Domain of unknown function (DUF370)
HMCHFCLE_00626	1.29e-260	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMCHFCLE_00627	6.21e-43	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein
HMCHFCLE_00628	2.94e-169	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMCHFCLE_00629	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMCHFCLE_00630	4.78e-22	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HMCHFCLE_00631	9.55e-88	rnpA	3.1.26.5	-	J	ko:K03536,ko:K08998	-	ko00000,ko01000,ko03016	ribonuclease P activity
HMCHFCLE_00632	5.98e-64	yidD	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HMCHFCLE_00633	5.69e-238	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
HMCHFCLE_00634	4e-196	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HMCHFCLE_00635	0.0	-	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
HMCHFCLE_00636	6.34e-310	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMCHFCLE_00637	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMCHFCLE_00638	2.05e-165	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HMCHFCLE_00639	1.13e-181	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HMCHFCLE_00640	1.31e-183	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain
HMCHFCLE_00641	1.63e-199	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HMCHFCLE_00642	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMCHFCLE_00645	8.13e-57	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
HMCHFCLE_00646	1.81e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
HMCHFCLE_00647	1.76e-154	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	phosphoglycolate phosphatase, bacterial
HMCHFCLE_00648	0.0	-	-	-	-	-	-	-	-
HMCHFCLE_00650	1.1e-158	-	-	-	C	ko:K03499	-	ko00000,ko02000	TrkA N-terminal domain protein
HMCHFCLE_00651	1.07e-94	trkA2	-	-	C	ko:K03499	-	ko00000,ko02000	TrkA N-terminal domain protein
HMCHFCLE_00652	2.07e-178	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HMCHFCLE_00653	1.25e-259	clcA	-	-	P	ko:K03281	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_00654	9.19e-266	-	-	-	C	ko:K07138	-	ko00000	Psort location Cytoplasmic, score
HMCHFCLE_00655	1.54e-111	-	-	-	-	-	-	-	-
HMCHFCLE_00656	6.12e-190	licT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	Psort location Cytoplasmic, score
HMCHFCLE_00657	0.0	glvC	2.7.1.199, 2.7.1.208	-	G	ko:K02749,ko:K02750,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_00658	0.0	-	3.2.1.122, 3.2.1.86	GH4,GT4	G	ko:K01222,ko:K01232	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HMCHFCLE_00659	1.11e-238	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon
HMCHFCLE_00660	3.17e-156	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00661	3.64e-307	-	-	-	V	-	-	-	MATE efflux family protein
HMCHFCLE_00662	0.0	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	CBS domain
HMCHFCLE_00663	3.58e-67	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HMCHFCLE_00667	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00668	9.83e-134	-	-	-	S	-	-	-	Domain of unknown function (DUF4194)
HMCHFCLE_00669	0.0	-	-	-	S	-	-	-	DNA replication and repair protein RecF
HMCHFCLE_00670	5.21e-310	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00671	1.5e-128	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HMCHFCLE_00673	4.56e-216	-	-	-	K	-	-	-	LysR substrate binding domain
HMCHFCLE_00674	0.0	cstA	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00675	2.7e-233	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00676	1.66e-215	-	-	-	K	-	-	-	LysR substrate binding domain
HMCHFCLE_00677	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN_bind
HMCHFCLE_00678	1.87e-305	-	-	-	V	-	-	-	MviN-like protein
HMCHFCLE_00682	3.25e-312	-	-	-	D	-	-	-	Phage tail tape measure protein, TP901 family
HMCHFCLE_00683	1.92e-19	-	-	-	-	-	-	-	-
HMCHFCLE_00684	6.12e-79	-	-	-	N	-	-	-	domain, Protein
HMCHFCLE_00685	2.38e-58	-	-	-	-	-	-	-	-
HMCHFCLE_00687	5.42e-64	-	-	-	-	-	-	-	-
HMCHFCLE_00689	2.59e-155	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00690	5.72e-84	-	-	-	S	-	-	-	Phage minor structural protein GP20
HMCHFCLE_00692	2.16e-121	-	-	-	-	-	-	-	-
HMCHFCLE_00693	9.12e-280	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HMCHFCLE_00694	8.74e-291	-	-	-	S	-	-	-	phage terminase, large subunit
HMCHFCLE_00696	1.08e-71	-	-	-	-	-	-	-	-
HMCHFCLE_00697	5.17e-36	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HMCHFCLE_00698	2.08e-94	-	-	-	L	-	-	-	DNA (cytosine-5-)-methyltransferase activity
HMCHFCLE_00701	8.69e-117	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HMCHFCLE_00703	1.91e-67	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HMCHFCLE_00707	1.03e-37	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00716	4.95e-21	-	-	-	-	-	-	-	-
HMCHFCLE_00717	1.02e-11	-	-	-	-	-	-	-	-
HMCHFCLE_00721	5.2e-59	-	-	-	S	-	-	-	Domain of unknown function (DUF4145)
HMCHFCLE_00722	1.56e-07	-	-	-	K	-	-	-	Helix-turn-helix domain
HMCHFCLE_00723	4.76e-49	-	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Psort location Cytoplasmic, score
HMCHFCLE_00724	5.22e-43	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
HMCHFCLE_00725	1.93e-171	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HMCHFCLE_00726	8.09e-33	-	-	-	S	-	-	-	Transglycosylase associated protein
HMCHFCLE_00727	1.51e-164	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMCHFCLE_00728	1.42e-308	yrvN	-	-	L	ko:K07478	-	ko00000	ATPase, AAA family
HMCHFCLE_00729	1.07e-92	-	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HMCHFCLE_00730	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HMCHFCLE_00731	1.79e-92	-	-	-	S	-	-	-	Belongs to the UPF0342 family
HMCHFCLE_00732	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMCHFCLE_00733	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMCHFCLE_00734	2.84e-178	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMCHFCLE_00735	1.54e-305	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMCHFCLE_00736	3.29e-104	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMCHFCLE_00737	4.88e-196	-	-	-	S	-	-	-	S4 domain protein
HMCHFCLE_00738	9.58e-147	-	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HMCHFCLE_00739	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMCHFCLE_00740	4.97e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMCHFCLE_00741	1.89e-228	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HMCHFCLE_00742	1.28e-188	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HMCHFCLE_00743	2.25e-76	-	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
HMCHFCLE_00744	0.0	ppk	2.7.4.1	-	H	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HMCHFCLE_00745	6.14e-122	-	-	-	M	-	-	-	Peptidase family M23
HMCHFCLE_00746	1.16e-118	-	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Peptidase M50
HMCHFCLE_00747	0.0	-	-	-	C	-	-	-	Radical SAM domain protein
HMCHFCLE_00748	5.76e-132	-	-	-	S	-	-	-	Radical SAM-linked protein
HMCHFCLE_00749	1.13e-72	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMCHFCLE_00750	4.12e-128	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HMCHFCLE_00751	2.46e-218	ylqF	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMCHFCLE_00752	1.63e-152	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMCHFCLE_00753	1.94e-83	-	-	-	L	ko:K07460	-	ko00000	Uncharacterised protein family UPF0102
HMCHFCLE_00754	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HMCHFCLE_00755	5.89e-161	-	-	-	S	ko:K07099	-	ko00000	Ser Thr phosphatase family protein
HMCHFCLE_00756	2.43e-108	-	-	-	S	ko:K02441	-	ko00000	Rhomboid family
HMCHFCLE_00757	5.39e-116	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00758	1.45e-298	rlmI	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HMCHFCLE_00759	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HMCHFCLE_00760	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HMCHFCLE_00761	1.93e-126	-	-	-	K	ko:K22010	-	ko00000,ko00002,ko02022	ANTAR domain protein
HMCHFCLE_00762	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMCHFCLE_00763	0.0	-	-	-	T	-	-	-	diguanylate cyclase
HMCHFCLE_00766	2.37e-188	-	-	-	G	-	-	-	polysaccharide deacetylase
HMCHFCLE_00767	9.39e-194	hmrR	-	-	K	-	-	-	Transcriptional regulator
HMCHFCLE_00768	0.0	apeA	-	-	E	-	-	-	M18 family aminopeptidase
HMCHFCLE_00769	1.69e-103	-	-	GH23	M	ko:K08309	-	ko00000,ko01000,ko01011	Transglycosylase SLT domain
HMCHFCLE_00770	5.63e-130	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMCHFCLE_00771	2.18e-245	sua	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMCHFCLE_00772	1.49e-253	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMCHFCLE_00773	6.69e-39	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00774	3e-223	-	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	S1 RNA binding domain protein
HMCHFCLE_00775	2.29e-125	-	-	-	K	-	-	-	Domain of unknown function (DUF4364)
HMCHFCLE_00776	4.62e-312	spoIVA	-	-	P	ko:K06398	-	ko00000	Stage IV sporulation protein A (spore_IV_A)
HMCHFCLE_00777	0.0	aspS	6.1.1.12, 6.1.1.23	-	J	ko:K01876,ko:K09759	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HMCHFCLE_00778	1.12e-148	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HMCHFCLE_00779	5.85e-295	-	-	-	V	-	-	-	MATE efflux family protein
HMCHFCLE_00780	4.48e-99	-	-	-	P	ko:K07238	-	ko00000,ko02000	Metal cation transporter, ZIP family
HMCHFCLE_00783	6.11e-118	yvdD	3.2.2.10	-	L	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HMCHFCLE_00784	2.95e-120	chrA2	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HMCHFCLE_00785	1.92e-120	chrA1	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HMCHFCLE_00786	2.15e-181	-	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HMCHFCLE_00787	2.6e-297	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMCHFCLE_00788	2.19e-188	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_00789	3.93e-181	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component I
HMCHFCLE_00790	2.47e-250	potA	3.6.3.31	-	P	ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMCHFCLE_00791	7.64e-205	-	-	-	S	-	-	-	Domain of unknown function (DUF4340)
HMCHFCLE_00792	0.0	-	-	-	N	ko:K01992	-	ko00000,ko00002,ko02000	transport system
HMCHFCLE_00793	1.42e-188	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HMCHFCLE_00794	7.66e-175	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
HMCHFCLE_00795	2.24e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HMCHFCLE_00797	1e-47	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HMCHFCLE_00798	8.14e-116	-	-	-	-	-	-	-	-
HMCHFCLE_00799	9.53e-41	-	-	-	J	-	-	-	tRNA cytidylyltransferase activity
HMCHFCLE_00801	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMCHFCLE_00802	6.46e-164	-	-	-	M	-	-	-	Male sterility protein
HMCHFCLE_00803	1.47e-127	-	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
HMCHFCLE_00804	1.64e-93	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HMCHFCLE_00805	1.37e-161	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HMCHFCLE_00806	5.82e-250	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HMCHFCLE_00807	4.92e-91	-	-	-	M	-	-	-	COG COG0463 Glycosyltransferases involved in cell wall biogenesis
HMCHFCLE_00808	2.75e-23	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HMCHFCLE_00809	8.36e-42	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HMCHFCLE_00811	2.23e-50	-	2.3.1.18	-	M	ko:K00633	-	ko00000,ko01000	Transferase hexapeptide repeat
HMCHFCLE_00812	2.57e-95	-	-	-	M	-	-	-	Glycosyl transferases group 1
HMCHFCLE_00813	1.84e-44	-	-	-	M	-	-	-	TIGRFAM glycosyl transferase, WecB TagA CpsF family
HMCHFCLE_00814	4.08e-291	wecB	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
HMCHFCLE_00815	8.93e-292	-	1.1.1.367	-	GM	ko:K19068	-	ko00000,ko01000	NAD dependent epimerase/dehydratase family
HMCHFCLE_00816	1.28e-69	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
HMCHFCLE_00817	1.02e-136	capD	5.1.3.2	-	M	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Polysaccharide biosynthesis protein
HMCHFCLE_00818	5.18e-149	cobH	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_00819	0.0	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HMCHFCLE_00820	1.73e-228	cobD_2	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_00821	5.76e-217	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HMCHFCLE_00822	1.66e-144	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_00823	3.85e-72	-	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
HMCHFCLE_00824	8.01e-175	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HMCHFCLE_00825	2.81e-112	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	adenosylcobinamide kinase adenosylcobinamide-phosphate guanylyltransferase
HMCHFCLE_00826	1.11e-240	cobT	2.4.2.21	-	H	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HMCHFCLE_00827	0.0	cbiA	6.3.5.11, 6.3.5.9	-	H	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HMCHFCLE_00828	6.63e-278	cbiT	2.1.1.132, 2.1.1.196	-	H	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit
HMCHFCLE_00829	1.88e-166	cobK	1.3.1.106, 1.3.1.54, 1.3.1.76, 4.99.1.4	-	H	ko:K02304,ko:K05895	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	reductase
HMCHFCLE_00830	3.05e-186	cobJ	2.1.1.131, 2.1.1.272	-	H	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-3B
HMCHFCLE_00831	1.65e-240	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
HMCHFCLE_00832	3.54e-179	cobM	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	precorrin-4 C11-methyltransferase
HMCHFCLE_00833	0.0	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HMCHFCLE_00834	4.2e-221	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMCHFCLE_00835	1.17e-271	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HMCHFCLE_00836	3.45e-180	-	-	-	HP	-	-	-	small periplasmic lipoprotein
HMCHFCLE_00837	2.7e-263	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_00838	1.9e-172	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
HMCHFCLE_00839	0.0	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HMCHFCLE_00840	7.62e-171	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HMCHFCLE_00841	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, C-terminal domain
HMCHFCLE_00842	3.93e-308	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family
HMCHFCLE_00843	9.17e-231	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00844	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HMCHFCLE_00845	5.16e-110	-	-	-	S	-	-	-	TIGRFAM C_GCAxxG_C_C family
HMCHFCLE_00846	2.05e-181	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HMCHFCLE_00847	2.21e-100	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HMCHFCLE_00848	5.09e-129	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HMCHFCLE_00849	8.47e-127	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	acetyltransferase (GNAT) family
HMCHFCLE_00850	9.49e-263	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HMCHFCLE_00851	1.75e-224	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HMCHFCLE_00852	1.05e-268	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
HMCHFCLE_00853	7.24e-284	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00855	1.8e-283	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HMCHFCLE_00856	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMCHFCLE_00857	2.33e-127	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HMCHFCLE_00858	1.33e-312	ynbB	-	-	P	-	-	-	Cystathionine beta-lyase family protein involved in aluminum resistance
HMCHFCLE_00859	1.37e-99	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HMCHFCLE_00860	1.17e-289	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMCHFCLE_00861	2.21e-184	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMCHFCLE_00862	2.29e-183	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMCHFCLE_00863	6.19e-107	-	-	-	K	-	-	-	dihydroxyacetone kinase regulator
HMCHFCLE_00864	0.0	-	-	-	C	-	-	-	Radical SAM domain protein
HMCHFCLE_00865	1.4e-267	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00866	0.0	cat	-	-	C	-	-	-	Acetyl-CoA hydrolase/transferase C-terminal domain
HMCHFCLE_00867	4.65e-123	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMCHFCLE_00868	4.35e-282	thlA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HMCHFCLE_00869	1.56e-182	crt	4.2.1.17	-	I	ko:K01715	ko00650,ko01200,map00650,map01200	ko00000,ko00001,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HMCHFCLE_00870	6.21e-208	hbd	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HMCHFCLE_00871	6.08e-274	bcd	1.3.8.1	-	C	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	Acyl-CoA dehydrogenase, C-terminal domain
HMCHFCLE_00872	9.44e-190	-	1.3.1.108	-	C	ko:K03521,ko:K22431	-	ko00000,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_00874	4.8e-26	-	-	-	-	-	-	-	-
HMCHFCLE_00875	0.0	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
HMCHFCLE_00876	2.05e-05	-	-	-	-	-	-	-	-
HMCHFCLE_00877	2.89e-126	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HMCHFCLE_00878	0.0	-	-	-	S	-	-	-	ABC transporter substrate-binding protein PnrA-like
HMCHFCLE_00879	6.08e-141	-	-	-	S	-	-	-	Protein of unknown function (DUF1643)
HMCHFCLE_00880	5.91e-73	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00883	3.86e-239	-	-	-	-	-	-	-	-
HMCHFCLE_00885	0.0	-	-	-	-	-	-	-	-
HMCHFCLE_00888	5.29e-239	-	-	-	-	-	-	-	-
HMCHFCLE_00889	2.04e-128	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HMCHFCLE_00890	0.0	-	-	-	-	-	-	-	-
HMCHFCLE_00891	0.0	-	-	-	S	-	-	-	Terminase-like family
HMCHFCLE_00893	2.29e-231	-	-	-	G	ko:K10540	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG COG1879 ABC-type sugar transport system, periplasmic component
HMCHFCLE_00894	0.0	mglA	3.6.3.17	-	G	ko:K10542	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC-type sugar transport system, ATPase component
HMCHFCLE_00895	3.75e-221	mglC	-	-	G	ko:K10541	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_00897	0.0	-	-	-	S	ko:K06972	-	ko00000,ko01000,ko01002	Peptidase M16C associated
HMCHFCLE_00898	1.22e-307	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	xanthine uracil permease family protein K06901
HMCHFCLE_00899	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HMCHFCLE_00900	1.02e-169	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HMCHFCLE_00901	0.0	-	-	CE1	Q	ko:K03932	-	ko00000	Esterase PHB depolymerase
HMCHFCLE_00902	1.82e-275	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribose-phosphate pyrophosphokinase family
HMCHFCLE_00903	8.66e-276	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMCHFCLE_00904	2.7e-277	-	-	-	T	-	-	-	diguanylate cyclase
HMCHFCLE_00905	2.31e-155	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HMCHFCLE_00907	8.16e-105	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00908	0.0	ispH	1.17.7.4	-	IJM	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HMCHFCLE_00909	1.12e-144	plsC_1	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HMCHFCLE_00910	1.22e-146	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HMCHFCLE_00911	3.62e-305	-	-	-	S	ko:K07007	-	ko00000	Flavoprotein family
HMCHFCLE_00912	1.45e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCHFCLE_00913	2.37e-243	-	-	-	G	-	-	-	Major Facilitator Superfamily
HMCHFCLE_00914	4.99e-155	-	-	-	M	-	-	-	Peptidase, M23 family
HMCHFCLE_00915	4.23e-295	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HMCHFCLE_00916	0.0	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
HMCHFCLE_00917	1.14e-172	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HMCHFCLE_00918	7.75e-40	-	-	-	P	ko:K10194	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCHFCLE_00919	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00920	1.3e-36	-	-	-	-	-	-	-	-
HMCHFCLE_00921	1.45e-93	-	-	-	S	ko:K06934	-	ko00000	Domain of unknown function (DUF296)
HMCHFCLE_00922	0.0	-	-	-	I	-	-	-	Lipase (class 3)
HMCHFCLE_00923	2.75e-213	-	-	-	K	-	-	-	LysR substrate binding domain protein
HMCHFCLE_00924	4.14e-176	-	-	-	S	-	-	-	TraX protein
HMCHFCLE_00927	7.52e-151	-	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	DNA-binding helix-turn-helix protein
HMCHFCLE_00928	0.0	-	-	-	L	-	-	-	DNA modification repair radical SAM protein
HMCHFCLE_00929	8.12e-194	-	-	-	L	-	-	-	DNA metabolism protein
HMCHFCLE_00930	2.02e-175	-	-	-	-	-	-	-	-
HMCHFCLE_00931	4.85e-58	spiA	-	-	K	ko:K18831	-	ko00000,ko02048,ko03000	sequence-specific DNA binding
HMCHFCLE_00932	1.33e-114	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMCHFCLE_00933	0.0	-	-	-	S	ko:K07137	-	ko00000	Oxidoreductase
HMCHFCLE_00934	2.24e-148	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HMCHFCLE_00935	3.73e-289	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00936	1.93e-139	-	-	-	F	-	-	-	Cytidylate kinase-like family
HMCHFCLE_00937	0.0	-	-	-	-	-	-	-	-
HMCHFCLE_00938	2.51e-197	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00939	1.81e-167	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HMCHFCLE_00940	4.01e-184	-	-	-	-	-	-	-	-
HMCHFCLE_00942	6.01e-246	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HMCHFCLE_00943	1.04e-246	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HMCHFCLE_00944	2.72e-261	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HMCHFCLE_00945	2.7e-295	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMCHFCLE_00946	6.66e-113	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HMCHFCLE_00947	1.65e-243	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	synthase
HMCHFCLE_00948	2.32e-298	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HMCHFCLE_00949	2e-207	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HMCHFCLE_00950	1.5e-229	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00951	0.0	-	-	-	O	-	-	-	ATPase, AAA family
HMCHFCLE_00952	7.95e-56	-	-	-	-	-	-	-	-
HMCHFCLE_00953	1.03e-237	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_00954	9.53e-208	cobW	-	-	S	-	-	-	CobW/HypB/UreG, nucleotide-binding domain
HMCHFCLE_00955	0.0	pepQ	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HMCHFCLE_00956	9.33e-123	rcoM2	-	-	KT	ko:K02477,ko:K21696	-	ko00000,ko02022,ko03000	phosphorelay signal transduction system
HMCHFCLE_00957	1.5e-231	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HMCHFCLE_00958	4.02e-158	-	-	-	S	-	-	-	IA, variant 3
HMCHFCLE_00959	8.31e-274	-	-	-	S	ko:K07001	-	ko00000	Psort location Cytoplasmic, score 8.96
HMCHFCLE_00960	0.0	-	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMCHFCLE_00961	1.9e-176	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMCHFCLE_00962	1.92e-209	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HMCHFCLE_00963	1.83e-145	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMCHFCLE_00964	4.64e-172	-	-	-	K	ko:K05799	-	ko00000,ko03000	Transcriptional regulator, GntR family
HMCHFCLE_00966	7.29e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMCHFCLE_00967	3.72e-145	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HMCHFCLE_00968	9.45e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMCHFCLE_00969	6.56e-64	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HMCHFCLE_00970	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HMCHFCLE_00971	3.64e-175	-	-	-	S	-	-	-	dinuclear metal center protein, YbgI
HMCHFCLE_00972	1.06e-135	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HMCHFCLE_00973	4.95e-57	-	-	-	C	-	-	-	Hydrid cluster protein-associated redox disulfide domain
HMCHFCLE_00974	6.57e-195	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_00975	1.89e-149	-	-	-	K	-	-	-	Belongs to the P(II) protein family
HMCHFCLE_00976	3.31e-298	-	-	-	T	-	-	-	Protein of unknown function (DUF1538)
HMCHFCLE_00977	0.0	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HMCHFCLE_00978	9.34e-130	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
HMCHFCLE_00979	2.07e-209	-	-	-	EG	-	-	-	EamA-like transporter family
HMCHFCLE_00980	3.84e-122	-	-	-	-	-	-	-	-
HMCHFCLE_00981	3.53e-247	-	-	-	M	-	-	-	lipoprotein YddW precursor K01189
HMCHFCLE_00985	0.0	-	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HMCHFCLE_00986	2.2e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HMCHFCLE_00987	2.2e-129	-	-	-	S	-	-	-	Belongs to the UPF0340 family
HMCHFCLE_00988	2e-301	-	3.1.1.17	-	G	ko:K01053,ko:K02352	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	ko00000,ko00001,ko00002,ko01000,ko04147	gluconolactonase activity
HMCHFCLE_00989	0.0	-	2.3.1.79	-	M	ko:K00661	-	ko00000,ko01000	Bacterial transferase hexapeptide (six repeats)
HMCHFCLE_00990	3.29e-163	resD	-	-	K	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HMCHFCLE_00991	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HMCHFCLE_00993	1.64e-239	-	3.1.1.11	-	G	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Pectinesterase
HMCHFCLE_00994	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HMCHFCLE_00995	6.16e-66	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
HMCHFCLE_00996	2.45e-62	-	-	-	-	-	-	-	-
HMCHFCLE_00997	0.0	gltX	6.1.1.17, 6.1.1.24	-	J	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMCHFCLE_00998	2.69e-76	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMCHFCLE_00999	0.0	-	-	-	O	ko:K03697	-	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
HMCHFCLE_01000	1.9e-127	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01001	4.22e-269	-	-	-	-	-	-	-	-
HMCHFCLE_01002	1.38e-177	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMCHFCLE_01003	8.63e-185	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMCHFCLE_01004	1.31e-216	cbiO	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMCHFCLE_01005	2.93e-196	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMCHFCLE_01006	5.86e-227	rlmL_1	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HMCHFCLE_01007	2.67e-251	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMCHFCLE_01008	1.44e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMCHFCLE_01009	1.52e-38	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HMCHFCLE_01010	2.21e-165	-	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HMCHFCLE_01011	3.08e-303	-	-	-	T	-	-	-	GHKL domain
HMCHFCLE_01012	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HMCHFCLE_01013	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 3 family
HMCHFCLE_01014	6.1e-135	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01015	5.68e-287	rny	-	-	D	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HMCHFCLE_01017	1.08e-271	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HMCHFCLE_01018	1.79e-99	-	-	-	-	-	-	-	-
HMCHFCLE_01019	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMCHFCLE_01020	0.0	-	-	-	P	ko:K03320	-	ko00000,ko02000	Belongs to the P(II) protein family
HMCHFCLE_01021	8.75e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1622)
HMCHFCLE_01022	9.48e-150	-	-	-	G	-	-	-	Ribose Galactose Isomerase
HMCHFCLE_01023	6.47e-76	-	-	-	S	-	-	-	Cupin domain
HMCHFCLE_01024	3.41e-190	-	1.1.1.69	-	IQ	ko:K00046	-	ko00000,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_01025	4.1e-176	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCHFCLE_01026	1.06e-258	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HMCHFCLE_01031	5.27e-164	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate binding protein
HMCHFCLE_01032	7.35e-198	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HMCHFCLE_01033	1.5e-176	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate ABC transporter
HMCHFCLE_01034	6.61e-181	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMCHFCLE_01035	2.03e-145	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HMCHFCLE_01036	1.17e-82	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HMCHFCLE_01037	1.25e-115	-	-	-	J	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01038	6.87e-229	-	-	-	JM	-	-	-	Nucleotidyl transferase
HMCHFCLE_01039	7.62e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01040	3.91e-194	ytrP	2.7.7.65	-	T	ko:K13069	-	ko00000,ko01000	diguanylate cyclase activity
HMCHFCLE_01041	0.0	-	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_01042	1.3e-283	alaXL	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Threonine alanine tRNA ligase second additional domain protein
HMCHFCLE_01043	7.79e-189	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMCHFCLE_01044	6.15e-40	-	-	-	S	-	-	-	Psort location
HMCHFCLE_01045	1.18e-211	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01046	0.0	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HMCHFCLE_01047	8.31e-135	-	-	-	C	-	-	-	FMN-binding domain protein
HMCHFCLE_01048	2.01e-63	-	-	-	C	-	-	-	FMN-binding domain protein
HMCHFCLE_01049	1.86e-302	-	-	-	S	-	-	-	Penicillin-binding protein Tp47 domain a
HMCHFCLE_01050	0.0	-	-	-	V	-	-	-	MATE efflux family protein
HMCHFCLE_01051	3.72e-189	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HMCHFCLE_01052	4.26e-108	-	-	-	S	-	-	-	small multi-drug export protein
HMCHFCLE_01053	0.0	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_01054	6.38e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF3842)
HMCHFCLE_01055	4.41e-133	-	-	-	S	-	-	-	metal-dependent phosphohydrolase, HD sub domain
HMCHFCLE_01056	4.45e-46	-	-	-	S	-	-	-	Transcriptional Coactivator p15 (PC4)
HMCHFCLE_01058	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	exonuclease SbcC
HMCHFCLE_01059	3.57e-227	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HMCHFCLE_01060	5.25e-111	-	-	-	M	-	-	-	Putative peptidoglycan binding domain
HMCHFCLE_01061	3.28e-141	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HMCHFCLE_01062	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HMCHFCLE_01063	4.12e-56	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HMCHFCLE_01064	2.04e-105	Lrp	-	-	K	-	-	-	Transcriptional regulator, AsnC family
HMCHFCLE_01065	1.54e-290	aspC	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
HMCHFCLE_01066	1.51e-201	ispE	2.7.1.148	-	I	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HMCHFCLE_01067	7.8e-31	-	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HMCHFCLE_01068	2.08e-159	-	-	-	-	-	-	-	-
HMCHFCLE_01069	3.5e-64	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HMCHFCLE_01070	1.49e-165	-	5.2.1.8	-	M	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMCHFCLE_01071	8.64e-97	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMCHFCLE_01072	0.0	addB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
HMCHFCLE_01073	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HMCHFCLE_01074	7.85e-126	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMCHFCLE_01075	4.37e-39	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HMCHFCLE_01076	7.5e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMCHFCLE_01077	7.99e-180	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMCHFCLE_01078	6.98e-214	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HMCHFCLE_01079	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMCHFCLE_01080	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HMCHFCLE_01081	8.79e-239	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMCHFCLE_01082	8.34e-155	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMCHFCLE_01083	4.39e-76	-	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HMCHFCLE_01084	4.01e-299	-	-	-	EG	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	ko00000,ko02000	Gluconate
HMCHFCLE_01085	3.26e-68	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HMCHFCLE_01086	5.11e-122	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01087	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HMCHFCLE_01088	1.97e-136	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HMCHFCLE_01090	6.86e-291	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMCHFCLE_01092	0.0	-	-	-	T	ko:K02667	ko02020,map02020	ko00000,ko00001,ko00002,ko02022,ko02035	phosphorelay signal transduction system
HMCHFCLE_01093	4.47e-295	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative sugar-binding N-terminal domain
HMCHFCLE_01094	2.21e-304	-	-	-	G	-	-	-	BNR repeat-like domain
HMCHFCLE_01095	1.76e-277	-	-	-	C	-	-	-	alcohol dehydrogenase
HMCHFCLE_01096	7.92e-218	-	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the DapA family
HMCHFCLE_01097	5.3e-265	pdxA	1.1.1.262, 1.1.1.408, 1.1.1.409	-	C	ko:K00097,ko:K22024	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the PdxA family
HMCHFCLE_01098	1.04e-286	-	-	-	P	-	-	-	arsenite transmembrane transporter activity
HMCHFCLE_01099	1.58e-81	-	-	-	G	-	-	-	Aldolase
HMCHFCLE_01100	2.8e-196	-	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger family protein
HMCHFCLE_01101	4.64e-197	-	-	-	K	-	-	-	transcriptional regulator RpiR family
HMCHFCLE_01102	7.17e-204	murQ	4.2.1.126	-	H	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HMCHFCLE_01103	0.0	-	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01104	1.13e-251	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HMCHFCLE_01105	7.52e-315	-	-	-	V	-	-	-	MATE efflux family protein
HMCHFCLE_01106	2.25e-202	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_01107	1.98e-142	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HMCHFCLE_01108	3.28e-179	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMCHFCLE_01109	1.18e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HMCHFCLE_01110	1.41e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMCHFCLE_01111	1.6e-146	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HMCHFCLE_01112	5.4e-252	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMCHFCLE_01113	1.69e-296	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMCHFCLE_01114	0.0	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HMCHFCLE_01115	7.5e-86	-	-	-	S	ko:K08978	-	ko00000,ko02000	EamA-like transporter family
HMCHFCLE_01116	3.54e-98	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HMCHFCLE_01117	2.49e-262	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01118	7.37e-251	-	-	-	S	-	-	-	Nitronate monooxygenase
HMCHFCLE_01119	2.42e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Psort location Cytoplasmic, score
HMCHFCLE_01120	1.85e-213	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMCHFCLE_01121	5.43e-228	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HMCHFCLE_01122	9.52e-205	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMCHFCLE_01123	3.48e-44	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMCHFCLE_01124	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMCHFCLE_01125	4.78e-316	-	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
HMCHFCLE_01126	5.51e-263	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMCHFCLE_01127	3.24e-291	-	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01128	4.82e-99	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMCHFCLE_01129	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMCHFCLE_01130	0.0	spoVD	3.4.16.4	-	M	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein
HMCHFCLE_01131	6.55e-102	-	-	-	-	-	-	-	-
HMCHFCLE_01132	3.99e-231	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMCHFCLE_01133	5.84e-47	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HMCHFCLE_01134	2.81e-75	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01135	1.59e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HMCHFCLE_01136	3.2e-150	-	-	-	C	-	-	-	NADPH-dependent FMN reductase
HMCHFCLE_01137	0.0	lacZ	3.2.1.23, 3.2.1.31	-	G	ko:K01190,ko:K01195	ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
HMCHFCLE_01138	3e-89	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HMCHFCLE_01139	1.66e-212	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01140	2.67e-166	-	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	Psort location Cytoplasmic, score
HMCHFCLE_01141	5.34e-62	-	-	-	-	-	-	-	-
HMCHFCLE_01142	3.16e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCHFCLE_01143	2.2e-150	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01144	1.38e-153	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HMCHFCLE_01145	2.73e-159	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01146	9.92e-211	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01147	3.69e-231	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase
HMCHFCLE_01148	7.93e-248	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Kinase, PfkB family
HMCHFCLE_01149	3.93e-216	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HMCHFCLE_01150	1.44e-185	-	1.1.1.69	-	IQ	ko:K00046	-	ko00000,ko01000	PFAM Short-chain dehydrogenase reductase SDR
HMCHFCLE_01151	5.64e-296	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01152	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMCHFCLE_01153	0.0	nagE	2.7.1.193	-	G	ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01154	6.73e-127	mutX	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Psort location Cytoplasmic, score 8.96
HMCHFCLE_01155	1.41e-65	-	-	-	G	-	-	-	Ricin-type beta-trefoil
HMCHFCLE_01156	2.61e-117	nfrA2	-	-	C	-	-	-	Nitroreductase family
HMCHFCLE_01157	1.37e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMCHFCLE_01158	1.66e-61	-	-	-	S	-	-	-	Trp repressor protein
HMCHFCLE_01159	3.36e-118	yajL	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
HMCHFCLE_01160	3.49e-216	-	-	-	Q	-	-	-	FAH family
HMCHFCLE_01161	6.1e-229	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_01162	0.0	-	3.1.3.5, 3.6.1.45	-	F	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HMCHFCLE_01163	5.46e-152	-	-	-	S	-	-	-	IA, variant 3
HMCHFCLE_01164	2.27e-272	ilvE	2.6.1.42, 4.1.3.38	-	E	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HMCHFCLE_01165	1.58e-193	-	-	-	S	-	-	-	Putative esterase
HMCHFCLE_01166	4.92e-204	-	-	-	S	-	-	-	Putative esterase
HMCHFCLE_01167	1.01e-312	-	-	-	F	-	-	-	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HMCHFCLE_01168	8.5e-303	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01169	9.1e-148	-	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Orotate phosphoribosyltransferase
HMCHFCLE_01170	3.47e-207	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0160)
HMCHFCLE_01171	7.31e-65	-	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HMCHFCLE_01173	7.92e-218	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMCHFCLE_01174	4.44e-293	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HMCHFCLE_01175	9.07e-198	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HMCHFCLE_01176	9.36e-295	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HMCHFCLE_01177	1.37e-218	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HMCHFCLE_01178	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HMCHFCLE_01179	7.5e-298	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMCHFCLE_01180	1.51e-237	-	-	-	S	ko:K07035	-	ko00000	Psort location CytoplasmicMembrane, score
HMCHFCLE_01181	1.37e-277	-	-	-	M	-	-	-	hydrolase, family 25
HMCHFCLE_01182	2.26e-135	-	-	-	S	-	-	-	Domain of unknown function (DUF4830)
HMCHFCLE_01183	2.51e-51	-	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier, HPr family
HMCHFCLE_01184	0.0	ptsP	2.7.3.9, 2.7.9.2	-	G	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMCHFCLE_01185	1.7e-113	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70 region 2
HMCHFCLE_01186	7.1e-43	-	-	-	S	-	-	-	Putative zinc-finger
HMCHFCLE_01187	1.24e-173	-	-	-	M	-	-	-	Peptidase, M23 family
HMCHFCLE_01188	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3
HMCHFCLE_01189	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain protein
HMCHFCLE_01190	2.32e-199	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HMCHFCLE_01191	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HMCHFCLE_01192	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 2
HMCHFCLE_01193	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
HMCHFCLE_01194	7.92e-306	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMCHFCLE_01195	9.12e-18	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01196	6.56e-149	-	1.1.1.100, 1.1.1.30	-	IQ	ko:K00019,ko:K00059	ko00061,ko00072,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00072,map00333,map00650,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HMCHFCLE_01197	8.59e-145	effD	-	-	V	-	-	-	MatE
HMCHFCLE_01198	1.35e-206	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HMCHFCLE_01199	2.35e-209	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HMCHFCLE_01200	0.0	rhaA	5.3.1.14	-	G	ko:K01813	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
HMCHFCLE_01201	1.37e-305	rhaB	2.7.1.5	-	H	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Carbohydrate kinase, FGGY family protein
HMCHFCLE_01202	6.44e-206	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HMCHFCLE_01203	9.47e-16	gufA	-	-	P	ko:K07238	-	ko00000,ko02000	Metal cation transporter, ZIP family
HMCHFCLE_01204	8.34e-86	-	-	-	S	-	-	-	Putative redox-active protein (C_GCAxxG_C_C)
HMCHFCLE_01205	9.95e-108	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMCHFCLE_01206	8.89e-113	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HMCHFCLE_01207	2.84e-155	-	-	-	S	-	-	-	Domain of unknown function (DUF5058)
HMCHFCLE_01208	1.53e-163	-	-	-	-	-	-	-	-
HMCHFCLE_01209	5.09e-203	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HMCHFCLE_01210	1.09e-64	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HMCHFCLE_01211	1.26e-292	-	-	-	M	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HMCHFCLE_01213	9.26e-270	fucO	1.1.1.77	-	C	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_01214	9.56e-317	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01215	2.18e-202	-	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger family protein
HMCHFCLE_01216	3.99e-20	-	-	-	C	-	-	-	NADH oxidase
HMCHFCLE_01217	9.32e-280	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HMCHFCLE_01219	3.04e-178	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HMCHFCLE_01220	3.71e-206	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HMCHFCLE_01221	5.58e-174	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HMCHFCLE_01222	7.73e-256	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Psort location Cytoplasmic, score
HMCHFCLE_01223	2.3e-161	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HMCHFCLE_01224	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMCHFCLE_01225	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphoribosylformylglycinamidine synthase
HMCHFCLE_01226	0.0	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HMCHFCLE_01227	2.1e-292	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	AICARFT IMPCHase bienzyme
HMCHFCLE_01228	3.29e-191	-	-	-	F	-	-	-	IMP cyclohydrolase-like protein
HMCHFCLE_01229	3.44e-132	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMCHFCLE_01230	5.65e-256	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HMCHFCLE_01231	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMCHFCLE_01232	3.71e-100	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMCHFCLE_01233	3.25e-107	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMCHFCLE_01234	1.2e-240	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	synthase
HMCHFCLE_01235	1.56e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3783)
HMCHFCLE_01236	6.67e-261	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMCHFCLE_01237	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMCHFCLE_01238	3.64e-174	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMCHFCLE_01239	6.77e-289	pgk	2.7.2.3, 5.3.1.1	-	G	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HMCHFCLE_01240	2.13e-227	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HMCHFCLE_01241	2.96e-208	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMCHFCLE_01242	4.67e-232	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
HMCHFCLE_01243	1.81e-85	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMCHFCLE_01244	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMCHFCLE_01245	5.95e-84	-	-	-	J	-	-	-	ribosomal protein
HMCHFCLE_01246	9.89e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Psort location Cytoplasmic, score 8.96
HMCHFCLE_01247	1.19e-258	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HMCHFCLE_01248	2.19e-31	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HMCHFCLE_01249	9.58e-80	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HMCHFCLE_01250	3.8e-296	dapL	2.6.1.83	-	H	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate
HMCHFCLE_01251	6.48e-209	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMCHFCLE_01252	4.33e-44	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMCHFCLE_01253	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
HMCHFCLE_01254	3.8e-224	-	-	-	G	-	-	-	Aldose 1-epimerase
HMCHFCLE_01255	1.84e-260	-	-	-	T	-	-	-	Histidine kinase
HMCHFCLE_01256	3.67e-154	-	-	-	T	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMCHFCLE_01257	3.46e-25	-	-	-	-	-	-	-	-
HMCHFCLE_01258	7.07e-196	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01259	6.87e-181	-	-	-	CO	ko:K06196	-	ko00000,ko02000	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HMCHFCLE_01260	0.0	-	-	-	M	-	-	-	peptidoglycan binding domain protein
HMCHFCLE_01261	3.86e-172	-	-	-	M	-	-	-	peptidoglycan binding domain protein
HMCHFCLE_01262	5.59e-114	-	-	-	C	-	-	-	Flavodoxin domain
HMCHFCLE_01263	8.69e-230	-	1.1.1.29, 1.1.1.399, 1.1.1.95	-	CH	ko:K00018,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
HMCHFCLE_01265	1.76e-173	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HMCHFCLE_01266	9.11e-85	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HMCHFCLE_01267	4.04e-204	-	-	-	T	-	-	-	cheY-homologous receiver domain
HMCHFCLE_01268	6e-41	-	-	-	S	-	-	-	Protein conserved in bacteria
HMCHFCLE_01269	4.16e-236	-	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
HMCHFCLE_01270	3.14e-276	-	2.7.1.165	-	G	ko:K11529	ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	MOFRL family
HMCHFCLE_01272	1.32e-291	-	-	-	M	-	-	-	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HMCHFCLE_01274	9.61e-70	-	-	-	S	-	-	-	No similarity found
HMCHFCLE_01275	1.67e-28	-	-	-	S	-	-	-	SGNH hydrolase-like domain, acetyltransferase AlgX
HMCHFCLE_01276	7.71e-66	-	-	-	M	ko:K19294	-	ko00000	Psort location CytoplasmicMembrane, score
HMCHFCLE_01278	2.68e-09	-	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HMCHFCLE_01279	4.35e-20	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HMCHFCLE_01280	6.55e-85	-	-	-	S	-	-	-	Replication initiator protein A domain protein
HMCHFCLE_01281	9.23e-167	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HMCHFCLE_01282	1.21e-163	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HMCHFCLE_01285	1.57e-37	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HMCHFCLE_01286	1.23e-171	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMCHFCLE_01287	3.59e-134	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMCHFCLE_01288	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMCHFCLE_01289	0.0	-	-	-	EK	-	-	-	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMCHFCLE_01290	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HMCHFCLE_01291	1.83e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMCHFCLE_01293	9.98e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HMCHFCLE_01294	0.0	-	-	-	EG	ko:K06295	-	ko00000	spore germination protein
HMCHFCLE_01297	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HMCHFCLE_01298	1.13e-154	phoB	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator receiver domain protein
HMCHFCLE_01299	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Na Pi-cotransporter II-like protein
HMCHFCLE_01300	9.61e-218	hprK	-	-	H	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMCHFCLE_01301	7.58e-213	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HMCHFCLE_01302	1.26e-185	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HMCHFCLE_01303	7.3e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HMCHFCLE_01304	0.0	dnaE	2.7.7.7	-	L	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
HMCHFCLE_01305	2.6e-233	pfkA	2.7.1.11	-	H	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMCHFCLE_01306	1.83e-88	-	-	-	S	-	-	-	YjbR
HMCHFCLE_01307	5.75e-160	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01308	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HMCHFCLE_01309	8.27e-36	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HMCHFCLE_01310	3.16e-258	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMCHFCLE_01311	6.86e-66	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01312	1.47e-154	-	-	-	L	-	-	-	AAA domain
HMCHFCLE_01313	3.01e-262	-	-	-	M	-	-	-	plasmid recombination
HMCHFCLE_01314	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HMCHFCLE_01315	1.72e-215	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_01316	1.61e-57	-	-	-	-	-	-	-	-
HMCHFCLE_01317	5.01e-42	-	-	-	-	-	-	-	-
HMCHFCLE_01318	1.56e-48	-	-	-	-	-	-	-	-
HMCHFCLE_01319	1.25e-143	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HMCHFCLE_01320	6.58e-169	-	-	-	P	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate ABC transporter membrane protein 1 CUT1 family
HMCHFCLE_01321	3e-162	-	-	-	G	ko:K10234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HMCHFCLE_01322	3.76e-294	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMCHFCLE_01323	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HMCHFCLE_01324	1.66e-24	-	-	-	-	-	-	-	-
HMCHFCLE_01326	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HMCHFCLE_01327	1.08e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMCHFCLE_01329	6.97e-157	-	-	-	E	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01330	2.71e-207	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HMCHFCLE_01331	1.5e-162	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HMCHFCLE_01332	2.35e-106	-	-	-	G	-	-	-	Domain of unknown function (DUF386)
HMCHFCLE_01333	6.04e-220	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the DapA family
HMCHFCLE_01334	6.52e-222	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01335	3.22e-214	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01336	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMCHFCLE_01337	2.21e-192	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HMCHFCLE_01338	4.41e-155	-	-	-	S	ko:K06890	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01339	9.2e-268	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HMCHFCLE_01341	5.91e-159	cpsE	-	-	M	-	-	-	sugar transferase
HMCHFCLE_01342	0.0	ilvD	4.2.1.9	-	EG	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HMCHFCLE_01343	1.1e-61	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HMCHFCLE_01344	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	phenylalanyl-tRNA synthetase (beta subunit)
HMCHFCLE_01345	1.48e-247	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMCHFCLE_01346	3.9e-234	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HMCHFCLE_01348	6.96e-263	yqfD	-	-	M	ko:K06438	-	ko00000	Putative stage IV sporulation protein YqfD
HMCHFCLE_01349	1.94e-195	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMCHFCLE_01350	8.39e-181	-	-	-	Q	-	-	-	Methyltransferase domain protein
HMCHFCLE_01351	1.72e-142	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HMCHFCLE_01352	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HMCHFCLE_01353	1.67e-117	-	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Psort location CytoplasmicMembrane, score
HMCHFCLE_01354	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HMCHFCLE_01355	4.83e-174	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_01357	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HMCHFCLE_01358	7.2e-130	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_01359	2.71e-72	-	-	-	-	-	-	-	-
HMCHFCLE_01360	7.41e-65	-	-	-	S	-	-	-	protein, YerC YecD
HMCHFCLE_01361	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Psort location CytoplasmicMembrane, score
HMCHFCLE_01362	1.63e-164	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HMCHFCLE_01363	1.75e-275	gcdB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	decarboxylase beta subunit
HMCHFCLE_01364	1.8e-59	-	-	-	C	-	-	-	decarboxylase gamma
HMCHFCLE_01365	9.51e-240	-	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein, MreB Mrl family
HMCHFCLE_01366	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMCHFCLE_01367	1.83e-231	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HMCHFCLE_01368	7.51e-193	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HMCHFCLE_01370	3.06e-141	-	-	-	S	-	-	-	Protein of unknown function (DUF1015)
HMCHFCLE_01371	0.0	rhlE	3.6.4.13	-	L	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Belongs to the DEAD box helicase family
HMCHFCLE_01372	2.01e-209	rlmA	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase
HMCHFCLE_01373	1.6e-292	-	-	-	I	-	-	-	Psort location Cytoplasmic, score 7.50
HMCHFCLE_01374	1.38e-315	-	-	-	V	-	-	-	MATE efflux family protein
HMCHFCLE_01375	0.0	-	-	-	E	ko:K03310	-	ko00000	amino acid carrier protein
HMCHFCLE_01377	2.38e-116	-	-	-	-	-	-	-	-
HMCHFCLE_01378	0.0	-	-	-	K	ko:K00375	-	ko00000,ko03000	Transcriptional regulator, GntR family
HMCHFCLE_01379	5.13e-141	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01380	5.4e-260	-	-	-	S	ko:K07007	-	ko00000	Flavoprotein family
HMCHFCLE_01381	7.99e-120	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein T
HMCHFCLE_01383	2.27e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMCHFCLE_01384	7.81e-119	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMCHFCLE_01385	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HMCHFCLE_01386	2.79e-275	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMCHFCLE_01389	2.43e-285	-	-	-	S	-	-	-	SGNH hydrolase-like domain, acetyltransferase AlgX
HMCHFCLE_01390	0.0	-	-	-	M	ko:K19294	-	ko00000	Psort location CytoplasmicMembrane, score
HMCHFCLE_01391	2.02e-47	-	-	-	S	-	-	-	Domain of unknown function (DUF4358)
HMCHFCLE_01392	5.02e-189	-	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Serine-type D-Ala-D-Ala carboxypeptidase
HMCHFCLE_01393	2.34e-97	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HMCHFCLE_01394	3.83e-233	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HMCHFCLE_01395	1.9e-70	spoVAE	-	-	S	ko:K06407	-	ko00000	Stage V sporulation protein AE
HMCHFCLE_01397	4.57e-45	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HMCHFCLE_01398	5.79e-314	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HMCHFCLE_01399	1.49e-293	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HMCHFCLE_01400	2.17e-287	-	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HMCHFCLE_01401	5.87e-169	-	-	-	C	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01402	5.28e-237	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01403	0.0	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HMCHFCLE_01404	3.22e-94	-	-	-	S	-	-	-	NusG domain II
HMCHFCLE_01405	0.0	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
HMCHFCLE_01406	1.75e-173	macB	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HMCHFCLE_01407	5.79e-270	macB1	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HMCHFCLE_01408	0.0	-	-	-	F	-	-	-	S-layer homology domain
HMCHFCLE_01409	7.76e-189	comF	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
HMCHFCLE_01411	4.37e-247	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HMCHFCLE_01412	4.22e-41	-	-	-	K	-	-	-	Helix-turn-helix domain
HMCHFCLE_01413	1.77e-197	-	-	-	K	-	-	-	DNA binding
HMCHFCLE_01414	2.05e-155	-	-	-	L	-	-	-	Toxic component of a toxin-antitoxin (TA) module
HMCHFCLE_01416	5.78e-73	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HMCHFCLE_01418	4.04e-55	-	-	-	P	-	-	-	glutathione-regulated potassium exporter activity
HMCHFCLE_01419	3.15e-49	pfbA	-	-	M	ko:K13925	ko05100,map05100	ko00000,ko00001	Pectate lyase superfamily protein
HMCHFCLE_01420	1.86e-142	-	-	-	G	-	-	-	Aldose 1-epimerase
HMCHFCLE_01421	4.55e-27	-	3.1.3.10	-	S	ko:K07025,ko:K20866	ko00010,ko01120,map00010,map01120	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant 3
HMCHFCLE_01422	9.44e-16	-	-	-	-	-	-	-	-
HMCHFCLE_01423	3.27e-47	-	-	-	-	-	-	-	-
HMCHFCLE_01424	4.87e-280	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMCHFCLE_01425	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HMCHFCLE_01426	0.0	-	-	-	S	ko:K01421	-	ko00000	Psort location Cellwall, score
HMCHFCLE_01427	0.0	-	-	-	S	ko:K07003	-	ko00000	Psort location CytoplasmicMembrane, score
HMCHFCLE_01428	2.16e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCHFCLE_01430	8.74e-62	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HMCHFCLE_01431	1.9e-26	-	-	-	D	-	-	-	Plasmid stabilization system
HMCHFCLE_01432	0.0	glpK	2.7.1.30	-	H	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMCHFCLE_01433	3.25e-70	-	-	-	KT	-	-	-	response regulator
HMCHFCLE_01434	2.12e-05	-	-	-	T	-	-	-	GHKL domain
HMCHFCLE_01435	0.0	-	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HMCHFCLE_01436	1.13e-270	-	-	-	S	-	-	-	Belongs to the UPF0348 family
HMCHFCLE_01437	5.16e-291	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMCHFCLE_01438	1.42e-70	-	-	-	K	-	-	-	Probable zinc-ribbon domain
HMCHFCLE_01439	2.18e-244	-	-	GT2	M	ko:K19427	-	ko00000,ko01000	Glycosyltransferase group 2 family protein
HMCHFCLE_01440	0.0	-	-	-	S	-	-	-	O-Antigen ligase
HMCHFCLE_01441	3.26e-79	-	-	-	M	-	-	-	Glycosyl transferases group 1
HMCHFCLE_01442	1.95e-291	-	-	-	V	-	-	-	Glycosyl transferase, family 2
HMCHFCLE_01443	0.0	-	-	-	M	-	-	-	Diguanylate cyclase, GGDEF domain
HMCHFCLE_01444	1.16e-302	-	-	-	-	-	-	-	-
HMCHFCLE_01445	9.5e-238	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase
HMCHFCLE_01446	2.54e-214	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMCHFCLE_01447	6.35e-126	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HMCHFCLE_01448	4.28e-143	-	-	-	S	-	-	-	EDD domain protein, DegV family
HMCHFCLE_01449	0.0	cls1	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMCHFCLE_01450	2e-221	-	-	-	-	-	-	-	-
HMCHFCLE_01451	2.93e-162	fliY1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HMCHFCLE_01452	8.74e-141	tcyB	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HMCHFCLE_01453	6.12e-184	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HMCHFCLE_01454	0.0	-	-	-	V	-	-	-	MATE efflux family protein
HMCHFCLE_01455	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	aconitate hydratase
HMCHFCLE_01456	4.23e-213	-	3.1.3.97	-	S	ko:K07053	-	ko00000,ko01000	PHP domain protein
HMCHFCLE_01457	1.83e-58	-	-	-	S	-	-	-	TSCPD domain
HMCHFCLE_01458	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
HMCHFCLE_01459	0.0	ushA	3.1.3.5, 3.6.1.45	-	F	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HMCHFCLE_01462	3.59e-21	scfA	-	-	S	-	-	-	RSAM-modified six-cysteine peptide
HMCHFCLE_01463	0.0	scfB	-	-	C	ko:K06871	-	ko00000	Radical SAM
HMCHFCLE_01464	0.0	-	4.1.1.18, 4.1.1.19	-	E	ko:K01582,ko:K01583,ko:K01585	ko00310,ko00330,ko00960,ko01100,ko01110,map00310,map00330,map00960,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Orn Lys Arg decarboxylase major
HMCHFCLE_01465	3.51e-143	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HMCHFCLE_01466	5.39e-181	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HMCHFCLE_01467	1.16e-207	-	-	-	C	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase catalytic
HMCHFCLE_01468	6.56e-182	-	1.4.1.21	-	S	ko:K06989	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	homoserine dehydrogenase
HMCHFCLE_01469	2.97e-33	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01470	3.32e-88	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HMCHFCLE_01471	1.59e-224	envE	3.1.4.46, 3.2.1.18, 3.2.1.8	GH33	E	ko:K01126,ko:K01181,ko:K01186	ko00511,ko00564,ko00600,ko04142,map00511,map00564,map00600,map04142	ko00000,ko00001,ko01000,ko02042	lipolytic protein G-D-S-L family
HMCHFCLE_01472	0.0	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HMCHFCLE_01473	5.74e-285	-	-	-	C	-	-	-	4Fe-4S dicluster domain
HMCHFCLE_01474	1.46e-214	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMCHFCLE_01475	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01476	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HMCHFCLE_01477	0.0	-	3.2.1.133, 3.2.1.135, 3.2.1.54, 3.5.4.33	GH13	G	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko03016	Alpha amylase, catalytic domain protein
HMCHFCLE_01478	2.71e-114	niaR	-	-	S	ko:K07105	-	ko00000	3H domain
HMCHFCLE_01479	1.57e-107	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01480	0.0	-	-	-	T	-	-	-	Diguanylate cyclase (GGDEF) domain protein
HMCHFCLE_01481	3.11e-219	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01482	4.07e-269	-	-	-	S	-	-	-	domain protein
HMCHFCLE_01483	3.73e-239	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HMCHFCLE_01484	6.28e-249	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HMCHFCLE_01485	1.43e-44	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
HMCHFCLE_01486	1.49e-97	-	-	-	K	-	-	-	Transcriptional regulator
HMCHFCLE_01487	1.32e-219	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HMCHFCLE_01488	1.68e-225	-	-	-	H	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMCHFCLE_01489	7.23e-51	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HMCHFCLE_01490	2.25e-86	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMCHFCLE_01491	1.25e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HMCHFCLE_01492	2.29e-308	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMCHFCLE_01493	1.47e-146	fabG5	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HMCHFCLE_01494	7.6e-118	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMCHFCLE_01495	1.14e-83	-	-	-	S	ko:K07052	-	ko00000	Psort location CytoplasmicMembrane, score
HMCHFCLE_01496	1.24e-200	-	-	-	S	-	-	-	EDD domain protein, DegV family
HMCHFCLE_01497	2.77e-174	yfcA	-	-	S	ko:K07090	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01498	3.2e-241	-	3.4.13.19	-	E	ko:K01273	-	ko00000,ko00537,ko01000,ko01002,ko04147	Renal dipeptidase family protein
HMCHFCLE_01499	0.0	-	2.7.11.1	-	KL	ko:K08282	-	ko00000,ko01000	SNF2 family
HMCHFCLE_01500	1.38e-270	-	-	-	T	-	-	-	diguanylate cyclase
HMCHFCLE_01501	1.14e-83	-	-	-	K	-	-	-	iron dependent repressor
HMCHFCLE_01502	5.19e-127	fumB	4.2.1.2	-	C	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Hydrolyase, tartrate beta subunit fumarate domain protein, Fe-S type
HMCHFCLE_01503	9.51e-202	fumA	4.2.1.2	-	C	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type
HMCHFCLE_01504	1.76e-278	-	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HMCHFCLE_01505	8.06e-184	tig_1	-	-	O	ko:K03545	-	ko00000	peptidylprolyl isomerase
HMCHFCLE_01506	3.04e-90	-	-	-	M	-	-	-	Domain of unknown function (DUF1972)
HMCHFCLE_01507	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMCHFCLE_01508	1.79e-110	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HMCHFCLE_01509	2.91e-23	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HMCHFCLE_01510	7.64e-88	-	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HMCHFCLE_01511	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMCHFCLE_01512	9.32e-190	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMCHFCLE_01513	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMCHFCLE_01514	5.22e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMCHFCLE_01515	4.13e-98	-	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMCHFCLE_01516	1.11e-55	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMCHFCLE_01517	1.56e-175	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HMCHFCLE_01518	2.44e-110	-	-	-	-	-	-	-	-
HMCHFCLE_01519	1.36e-46	-	-	-	S	-	-	-	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
HMCHFCLE_01520	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HMCHFCLE_01521	1.67e-273	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
HMCHFCLE_01522	2.05e-260	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HMCHFCLE_01523	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HMCHFCLE_01524	6.49e-201	yabE	-	-	S	-	-	-	G5 domain
HMCHFCLE_01525	0.0	-	-	-	N	-	-	-	domain, Protein
HMCHFCLE_01526	1.79e-32	-	-	-	-	-	-	-	-
HMCHFCLE_01527	7.79e-166	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
HMCHFCLE_01528	1.8e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HMCHFCLE_01529	1.46e-304	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMCHFCLE_01530	2.92e-108	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMCHFCLE_01531	4.17e-234	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HMCHFCLE_01532	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HMCHFCLE_01533	3.36e-216	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HMCHFCLE_01534	3.52e-111	-	-	-	K	-	-	-	MarR family
HMCHFCLE_01535	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HMCHFCLE_01536	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01537	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HMCHFCLE_01538	0.0	-	-	-	S	-	-	-	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HMCHFCLE_01539	7.74e-241	-	-	-	-	-	-	-	-
HMCHFCLE_01540	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMCHFCLE_01541	1.42e-137	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMCHFCLE_01543	2.92e-32	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMCHFCLE_01544	4.71e-135	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMCHFCLE_01545	1.25e-118	ptbA	-	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMCHFCLE_01546	6.5e-271	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HMCHFCLE_01547	2.09e-245	-	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HMCHFCLE_01549	4.87e-163	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_01550	6e-68	-	-	-	S	-	-	-	regulation of response to stimulus
HMCHFCLE_01551	6.13e-165	-	-	-	K	-	-	-	Helix-turn-helix
HMCHFCLE_01556	6.52e-93	-	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
HMCHFCLE_01557	3.19e-157	-	-	-	S	-	-	-	hydrolase of the alpha beta superfamily
HMCHFCLE_01558	7.18e-145	-	-	-	S	-	-	-	YheO-like PAS domain
HMCHFCLE_01559	2.17e-81	TdcF	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
HMCHFCLE_01560	2.72e-300	-	-	-	S	-	-	-	Belongs to the UPF0597 family
HMCHFCLE_01561	7.4e-275	-	-	-	C	-	-	-	Sodium:dicarboxylate symporter family
HMCHFCLE_01562	4.16e-279	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMCHFCLE_01563	7.06e-292	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	PFAM Aminotransferase class I and II
HMCHFCLE_01564	2.22e-299	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
HMCHFCLE_01565	3.32e-136	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01566	4.41e-168	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HMCHFCLE_01568	3.41e-193	-	-	-	J	-	-	-	SpoU rRNA Methylase family
HMCHFCLE_01569	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01572	7.62e-10	-	-	-	T	-	-	-	Histidine kinase
HMCHFCLE_01573	4.46e-194	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HMCHFCLE_01574	1.57e-190	-	-	-	S	-	-	-	HAD hydrolase, family IIB
HMCHFCLE_01575	9.14e-88	-	-	-	S	-	-	-	YjbR
HMCHFCLE_01576	5.51e-73	-	-	-	-	-	-	-	-
HMCHFCLE_01577	4.64e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2500)
HMCHFCLE_01578	3.17e-111	hsp18	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HMCHFCLE_01579	5.21e-154	-	-	-	K	-	-	-	FCD
HMCHFCLE_01580	0.0	NPD5_3681	-	-	E	-	-	-	amino acid
HMCHFCLE_01581	0.0	apeB	3.4.11.21	-	E	ko:K01267	-	ko00000,ko01000,ko01002,ko04131	M18 family aminopeptidase
HMCHFCLE_01582	5.44e-104	-	-	-	F	-	-	-	Belongs to the 5'-nucleotidase family
HMCHFCLE_01583	0.0	-	-	-	T	-	-	-	Response regulator receiver domain protein
HMCHFCLE_01584	5.08e-200	-	-	-	FG	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMCHFCLE_01585	3.66e-118	-	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HMCHFCLE_01586	4.48e-152	-	-	-	K	-	-	-	FCD
HMCHFCLE_01587	1.07e-139	-	-	-	S	-	-	-	Cytoplasmic, score 8.87
HMCHFCLE_01588	5.39e-184	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HMCHFCLE_01589	1.81e-203	-	-	-	P	ko:K05832	-	ko00000,ko00002,ko02000	Branched-chain amino acid ABC transporter, permease protein
HMCHFCLE_01590	1.66e-232	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
HMCHFCLE_01591	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01592	1.47e-136	yfbR	3.1.3.89	-	S	ko:K07023,ko:K08722	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	PFAM metal-dependent phosphohydrolase HD sub domain
HMCHFCLE_01593	2.76e-247	dus	-	-	H	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMCHFCLE_01594	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HMCHFCLE_01595	3.78e-96	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HMCHFCLE_01596	9.85e-197	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HMCHFCLE_01597	4.39e-268	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HMCHFCLE_01598	1.8e-23	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HMCHFCLE_01599	4.49e-46	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMCHFCLE_01600	1.75e-129	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HMCHFCLE_01601	8.03e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMCHFCLE_01602	1.68e-157	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMCHFCLE_01603	6.99e-53	nifJ	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HMCHFCLE_01604	5.71e-58	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HMCHFCLE_01605	8.65e-81	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HMCHFCLE_01606	0.0	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HMCHFCLE_01608	1.56e-145	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01609	1.44e-208	-	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III, delta subunit
HMCHFCLE_01610	2.61e-73	PaaY	-	-	S	ko:K02617	-	ko00000	Bacterial transferase hexapeptide repeat protein
HMCHFCLE_01611	7.17e-296	-	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HMCHFCLE_01612	4.33e-186	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	biotin acetyl-CoA-carboxylase ligase
HMCHFCLE_01613	1.21e-83	yfcE1	-	-	S	ko:K07095	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HMCHFCLE_01614	1.38e-191	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMCHFCLE_01615	2.21e-155	yfiC	2.1.1.223	-	S	ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HMCHFCLE_01616	8.06e-17	-	-	-	C	-	-	-	4Fe-4S binding domain
HMCHFCLE_01617	6.86e-228	yaaT	-	-	S	-	-	-	PSP1 C-terminal domain protein
HMCHFCLE_01618	0.0	czcA	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HMCHFCLE_01619	3.59e-154	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMCHFCLE_01620	8.86e-62	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein, YhbY family
HMCHFCLE_01621	6.64e-146	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMCHFCLE_01622	1.31e-133	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	HD superfamily hydrolase involved in NAD metabolism
HMCHFCLE_01623	2.28e-284	-	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HMCHFCLE_01624	1.39e-83	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMCHFCLE_01625	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HMCHFCLE_01626	5.46e-27	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HMCHFCLE_01627	1.31e-114	yqeG	-	-	S	ko:K07015	-	ko00000	Mitochondrial PGP phosphatase
HMCHFCLE_01628	3.32e-184	Nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV
HMCHFCLE_01629	7.39e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMCHFCLE_01630	2.91e-72	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01631	3.13e-65	-	-	-	-	-	-	-	-
HMCHFCLE_01632	5.3e-209	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HMCHFCLE_01633	0.0	fhs	6.3.4.3	-	H	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HMCHFCLE_01634	1.33e-274	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	aminotransferase class V
HMCHFCLE_01635	1.29e-281	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMCHFCLE_01636	1.48e-304	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HMCHFCLE_01638	2.08e-62	ziaR	-	-	K	ko:K21903	-	ko00000,ko03000	regulatory protein, arsR
HMCHFCLE_01639	6.33e-46	-	-	-	C	-	-	-	Heavy metal-associated domain protein
HMCHFCLE_01640	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
HMCHFCLE_01641	2.77e-150	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMCHFCLE_01642	3.78e-271	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMCHFCLE_01646	9.8e-167	-	-	-	T	-	-	-	response regulator receiver
HMCHFCLE_01647	0.0	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HMCHFCLE_01648	2.06e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HMCHFCLE_01649	8.49e-242	-	-	-	C	ko:K03614	-	ko00000	Belongs to the NqrB RnfD family
HMCHFCLE_01650	1.27e-162	-	-	-	C	ko:K03613	-	ko00000	Psort location CytoplasmicMembrane, score
HMCHFCLE_01651	1.29e-102	-	-	-	C	ko:K03617	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01652	6.31e-224	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
HMCHFCLE_01653	6.41e-107	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HMCHFCLE_01654	1.87e-269	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMCHFCLE_01655	6.52e-222	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMCHFCLE_01656	9.36e-227	prmC	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01657	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HMCHFCLE_01658	2.31e-166	-	-	-	K	-	-	-	response regulator receiver
HMCHFCLE_01659	5.6e-308	-	-	-	S	-	-	-	Tetratricopeptide repeat
HMCHFCLE_01660	2.75e-72	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HMCHFCLE_01661	3.11e-222	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMCHFCLE_01662	3.58e-135	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMCHFCLE_01663	1.25e-88	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMCHFCLE_01664	3.46e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMCHFCLE_01665	2.29e-15	rpmJ	-	-	J	-	-	-	Belongs to the bacterial ribosomal protein bL36 family
HMCHFCLE_01666	8.01e-59	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMCHFCLE_01667	4.28e-181	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HMCHFCLE_01668	7.77e-144	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMCHFCLE_01669	3.22e-288	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMCHFCLE_01670	2.45e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HMCHFCLE_01671	3.69e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein
HMCHFCLE_01672	6.22e-108	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMCHFCLE_01673	4.64e-76	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMCHFCLE_01674	1.05e-130	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMCHFCLE_01675	2.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMCHFCLE_01676	1.67e-38	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMCHFCLE_01677	3.45e-57	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMCHFCLE_01679	0.0	-	-	-	-	-	-	-	-
HMCHFCLE_01680	1.52e-195	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01681	0.0	-	-	-	S	-	-	-	Heparinase II/III-like protein
HMCHFCLE_01682	7.21e-300	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HMCHFCLE_01683	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HMCHFCLE_01684	3.04e-297	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Carbohydrate ABC transporter substrate-binding protein, CUT1 family (TC 3.A.1.1.-)
HMCHFCLE_01685	1.67e-221	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC transporter
HMCHFCLE_01686	1.83e-198	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Carbohydrate ABC transporter membrane protein 2, CUT1 family
HMCHFCLE_01687	0.0	-	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolases family 2
HMCHFCLE_01688	1.67e-297	-	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HMCHFCLE_01689	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2264)
HMCHFCLE_01690	3.8e-223	-	-	-	P	ko:K02025,ko:K10193	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate ABC transporter membrane protein 1 CUT1 family
HMCHFCLE_01691	0.0	-	-	-	G	ko:K02027,ko:K10192	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HMCHFCLE_01692	9.57e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HMCHFCLE_01693	8.11e-152	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMCHFCLE_01694	3.41e-160	tepA	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score
HMCHFCLE_01695	0.0	spoIIIE	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HMCHFCLE_01696	0.0	-	-	-	C	-	-	-	UPF0313 protein
HMCHFCLE_01697	1.78e-216	-	-	-	J	ko:K02238	-	ko00000,ko00002,ko02044	Metallo-beta-lactamase domain protein
HMCHFCLE_01698	2.95e-96	-	-	-	-	-	-	-	-
HMCHFCLE_01699	0.0	gltA2	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	citrate synthase
HMCHFCLE_01700	6.63e-95	-	-	-	K	-	-	-	Transcriptional regulator, BlaI MecI CopY family
HMCHFCLE_01701	6.21e-266	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HMCHFCLE_01703	7.73e-24	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_01704	9.46e-233	-	-	-	S	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HMCHFCLE_01705	5.5e-89	-	-	-	K	-	-	-	AraC-like ligand binding domain
HMCHFCLE_01706	7.65e-18	-	-	-	G	-	-	-	TRAP transporter, DctM subunit
HMCHFCLE_01707	3.91e-57	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
HMCHFCLE_01708	1.42e-210	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HMCHFCLE_01709	2.11e-71	-	-	-	H	-	-	-	Catalyzes the conversion of L-arabinose to L-ribulose
HMCHFCLE_01710	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01711	0.0	-	-	-	V	-	-	-	antibiotic catabolic process
HMCHFCLE_01712	8.43e-77	-	-	-	KT	-	-	-	Response regulator of the LytR AlgR family
HMCHFCLE_01713	2.47e-164	-	-	-	KT	-	-	-	LytTr DNA-binding domain
HMCHFCLE_01714	3.1e-282	-	-	-	T	-	-	-	GHKL domain
HMCHFCLE_01715	3.08e-302	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HMCHFCLE_01716	5.62e-55	-	-	-	S	-	-	-	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121
HMCHFCLE_01717	0.0	copA_1	-	-	P	ko:K12950	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
HMCHFCLE_01718	8.46e-97	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01719	1.7e-313	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HMCHFCLE_01720	6.23e-212	-	-	-	K	-	-	-	LysR substrate binding domain protein
HMCHFCLE_01721	5.05e-233	-	-	-	G	-	-	-	TRAP transporter solute receptor, DctP family
HMCHFCLE_01722	2.22e-280	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01723	2.66e-120	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01724	5.74e-244	-	-	-	G	-	-	-	TRAP transporter solute receptor, DctP family
HMCHFCLE_01725	3.51e-180	-	-	-	K	-	-	-	Response regulator receiver domain
HMCHFCLE_01726	0.0	-	-	-	T	-	-	-	Histidine kinase
HMCHFCLE_01727	6.9e-157	-	-	-	K	-	-	-	Cyclic nucleotide-binding domain protein
HMCHFCLE_01728	1.65e-155	-	-	-	C	-	-	-	4Fe-4S binding domain protein
HMCHFCLE_01730	2.7e-185	-	-	-	S	-	-	-	Cupin domain
HMCHFCLE_01731	1.36e-144	-	-	-	S	-	-	-	Aldo/keto reductase family
HMCHFCLE_01732	7.69e-120	-	-	-	S	-	-	-	Flavin reductase
HMCHFCLE_01733	2.5e-104	-	-	-	K	-	-	-	Transcriptional regulator
HMCHFCLE_01734	6.47e-53	-	-	-	-	-	-	-	-
HMCHFCLE_01737	1.4e-213	tig	-	-	D	ko:K03545	-	ko00000	peptidyl-prolyl cis-trans isomerase activity
HMCHFCLE_01738	2.23e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
HMCHFCLE_01739	2.2e-253	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01740	1.76e-194	-	-	-	S	-	-	-	Cof-like hydrolase
HMCHFCLE_01741	0.0	phoA	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HMCHFCLE_01742	2.97e-75	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMCHFCLE_01743	5.35e-226	-	-	-	-	-	-	-	-
HMCHFCLE_01744	3.29e-165	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01745	1.19e-234	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HMCHFCLE_01749	1.26e-107	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HMCHFCLE_01750	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMCHFCLE_01751	1.1e-257	-	-	-	S	-	-	-	Acyltransferase family
HMCHFCLE_01752	9.61e-246	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HMCHFCLE_01753	8.44e-176	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HMCHFCLE_01754	0.0	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HMCHFCLE_01755	3.24e-249	dmpA	3.4.11.19	-	EQ	ko:K01266	-	ko00000,ko01000,ko01002	Peptidase family S58
HMCHFCLE_01756	4.77e-305	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01757	2.25e-245	-	-	-	S	-	-	-	AI-2E family transporter
HMCHFCLE_01758	3.34e-65	lrgB	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01759	2.36e-51	-	-	-	P	-	-	-	mercury ion transmembrane transporter activity
HMCHFCLE_01760	9.92e-207	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01761	0.0	malP_1	2.4.1.1	GT35	F	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMCHFCLE_01762	5.51e-158	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HMCHFCLE_01763	2.4e-33	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03425	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein secretion
HMCHFCLE_01764	5.47e-49	-	-	-	U	ko:K03117	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	mttA/Hcf106 family
HMCHFCLE_01765	0.0	-	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC-type multidrug transport system ATPase and permease
HMCHFCLE_01766	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HMCHFCLE_01767	4.83e-253	-	-	-	S	-	-	-	Sel1-like repeats.
HMCHFCLE_01768	0.0	-	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HMCHFCLE_01769	3.2e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF1653)
HMCHFCLE_01770	6.8e-151	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HMCHFCLE_01772	1.06e-100	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01776	9.1e-65	-	-	-	S	-	-	-	Stress responsive A/B Barrel Domain
HMCHFCLE_01777	6.59e-52	-	-	-	-	-	-	-	-
HMCHFCLE_01778	1.57e-196	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, TatD family
HMCHFCLE_01779	1.69e-231	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01780	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMCHFCLE_01781	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMCHFCLE_01782	3.46e-61	gap	1.2.1.12	-	C	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMCHFCLE_01783	2.23e-188	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01784	3.14e-294	-	-	-	S	-	-	-	Penicillin-binding protein Tp47 domain a
HMCHFCLE_01785	7.58e-182	-	-	-	C	-	-	-	FMN-binding domain protein
HMCHFCLE_01786	5.21e-92	-	-	-	S	-	-	-	FMN_bind
HMCHFCLE_01787	4.36e-210	-	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01788	1.41e-29	copA_1	-	-	P	ko:K12950	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
HMCHFCLE_01790	1.62e-64	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HMCHFCLE_01791	1.79e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
HMCHFCLE_01792	1.14e-199	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HMCHFCLE_01793	4.9e-248	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HMCHFCLE_01794	3.09e-139	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMCHFCLE_01795	2.55e-216	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMCHFCLE_01796	1.64e-191	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HMCHFCLE_01797	5.32e-208	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
HMCHFCLE_01798	5.84e-296	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMCHFCLE_01800	1.76e-160	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine O-acetyltransferase
HMCHFCLE_01801	0.0	-	-	-	T	ko:K07814	-	ko00000,ko02022	HD domain
HMCHFCLE_01803	3.3e-232	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMCHFCLE_01804	2.01e-185	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HMCHFCLE_01807	7.43e-257	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01808	2.73e-212	-	2.7.1.15, 2.7.1.83	-	H	ko:K00852,ko:K16328	ko00030,ko00240,map00030,map00240	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HMCHFCLE_01809	1.79e-216	-	2.7.1.40	-	H	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase, barrel domain
HMCHFCLE_01810	2.22e-131	yfcE	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HMCHFCLE_01811	1.06e-295	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01812	0.0	agcS_2	-	-	E	ko:K03310	-	ko00000	amino acid carrier protein
HMCHFCLE_01813	8.46e-268	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
HMCHFCLE_01814	1.66e-137	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HMCHFCLE_01815	2.06e-234	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HMCHFCLE_01817	2.65e-273	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMCHFCLE_01818	8.36e-39	-	-	-	K	-	-	-	Penicillinase repressor
HMCHFCLE_01819	4.23e-14	-	-	-	KT	-	-	-	BlaR1 peptidase M56
HMCHFCLE_01820	2.31e-130	-	-	-	F	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01821	6.51e-140	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HMCHFCLE_01822	2.81e-36	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	Fe2 transport system protein A
HMCHFCLE_01823	1.75e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	Fe2 transport system protein A
HMCHFCLE_01824	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HMCHFCLE_01825	1.27e-14	-	-	-	-	-	-	-	-
HMCHFCLE_01826	3.81e-82	-	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
HMCHFCLE_01827	2.72e-193	-	-	GT2,GT4	M	ko:K07011,ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 21
HMCHFCLE_01828	0.0	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase, group 2 family protein
HMCHFCLE_01829	3.2e-208	-	-	-	D	ko:K06381	-	ko00000	sporulation resulting in formation of a cellular spore
HMCHFCLE_01831	0.0	-	-	-	L	-	-	-	Phage integrase family
HMCHFCLE_01832	6.04e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HMCHFCLE_01833	7.48e-194	-	-	-	K	-	-	-	DNA binding
HMCHFCLE_01834	6.73e-130	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HMCHFCLE_01836	7.63e-112	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HMCHFCLE_01837	1.58e-92	-	1.15.1.2	-	C	ko:K05919	-	ko00000,ko01000	Superoxide reductase
HMCHFCLE_01838	1.34e-127	-	-	-	C	-	-	-	Rubrerythrin
HMCHFCLE_01839	2.33e-12	-	-	-	-	-	-	-	-
HMCHFCLE_01840	3.32e-88	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HMCHFCLE_01841	8.93e-229	-	-	-	T	-	-	-	Response regulator receiver domain protein
HMCHFCLE_01842	1.49e-110	-	3.1.3.5, 3.6.1.45	-	FG	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Bacterial extracellular solute-binding protein
HMCHFCLE_01843	5e-37	-	-	-	-	-	-	-	-
HMCHFCLE_01844	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HMCHFCLE_01845	6.2e-103	-	-	-	-	-	-	-	-
HMCHFCLE_01846	1.52e-203	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HMCHFCLE_01847	1.68e-205	-	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
HMCHFCLE_01848	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HMCHFCLE_01849	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HMCHFCLE_01850	6.73e-107	-	-	-	-	-	-	-	-
HMCHFCLE_01852	1.92e-89	-	1.15.1.2	-	C	ko:K05919	-	ko00000,ko01000	Superoxide reductase
HMCHFCLE_01853	1.36e-242	-	-	-	T	-	-	-	domain protein
HMCHFCLE_01854	1.34e-152	nnrE	5.1.99.6	-	G	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HMCHFCLE_01855	3.55e-71	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMCHFCLE_01856	0.0	apu	2.4.1.25, 3.2.1.133, 3.2.1.135, 3.2.1.20, 3.2.1.54	GH13,GH31,GH77	G	ko:K00705,ko:K01187,ko:K01208	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HMCHFCLE_01857	5.69e-100	-	-	-	OU	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01858	1.28e-155	qmcA	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
HMCHFCLE_01860	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMCHFCLE_01861	0.0	capD	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
HMCHFCLE_01862	1.68e-250	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	Stage V sporulation protein B
HMCHFCLE_01865	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	COG COG1653 ABC-type sugar transport system, periplasmic component
HMCHFCLE_01866	0.0	-	-	-	KT	-	-	-	transcriptional regulator LuxR family
HMCHFCLE_01867	4.19e-292	-	-	-	T	-	-	-	Response regulator receiver domain protein
HMCHFCLE_01868	1.96e-183	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HMCHFCLE_01869	2.68e-123	-	-	-	K	-	-	-	Acetyltransferase GNAT family
HMCHFCLE_01870	9.84e-184	yoaP	-	-	E	-	-	-	YoaP-like
HMCHFCLE_01872	9.36e-226	PflX	1.97.1.4	-	C	ko:K04070	-	ko00000,ko01000	pyruvate formate lyase activating
HMCHFCLE_01873	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
HMCHFCLE_01874	4.77e-289	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMCHFCLE_01875	9.83e-191	yycJ	-	-	S	-	-	-	Metallo-beta-lactamase domain protein
HMCHFCLE_01876	2.26e-219	dnaC	-	-	L	ko:K02315	-	ko00000,ko03032	DNA replication protein
HMCHFCLE_01877	3.61e-214	dnaD	-	-	-	ko:K02086	-	ko00000	-
HMCHFCLE_01878	1.53e-89	-	-	-	-	-	-	-	-
HMCHFCLE_01879	4e-265	-	2.4.1.319, 2.4.1.320	-	G	ko:K18785	-	ko00000,ko01000	beta-1,4-mannooligosaccharide phosphorylase
HMCHFCLE_01880	6.36e-303	-	5.1.3.11	-	G	ko:K16213	-	ko00000,ko01000	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)
HMCHFCLE_01881	1.82e-299	-	2.4.1.281	-	F	ko:K16212	-	ko00000,ko01000	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
HMCHFCLE_01882	1.18e-155	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HMCHFCLE_01883	0.0	-	5.4.2.2, 5.4.2.8	-	G	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HMCHFCLE_01884	6.86e-228	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase, class I
HMCHFCLE_01885	1.11e-114	-	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
HMCHFCLE_01886	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HMCHFCLE_01887	5.86e-191	fliY1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HMCHFCLE_01888	1.6e-103	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMCHFCLE_01889	0.0	-	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	PFAM DNA gyrase topoisomerase IV, subunit A
HMCHFCLE_01890	0.0	-	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase
HMCHFCLE_01892	9.12e-261	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HMCHFCLE_01893	4.3e-229	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HMCHFCLE_01894	1.18e-275	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HMCHFCLE_01895	1.45e-232	-	-	-	K	ko:K02529	-	ko00000,ko03000	PFAM periplasmic binding protein LacI transcriptional regulator
HMCHFCLE_01896	0.0	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
HMCHFCLE_01897	7.58e-217	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC transporter
HMCHFCLE_01899	9.37e-311	-	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_01900	5.25e-149	ktrA	-	-	C	ko:K03499	-	ko00000,ko02000	system potassium uptake protein
HMCHFCLE_01901	0.0	kdpD	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HMCHFCLE_01902	2.3e-167	kdpE	-	-	K	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	transcriptional regulatory protein KdpE
HMCHFCLE_01903	5.62e-55	-	-	-	S	-	-	-	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121
HMCHFCLE_01904	0.0	copA_1	-	-	P	ko:K12950	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
HMCHFCLE_01905	1.57e-51	malP_1	2.4.1.1	GT35	F	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMCHFCLE_01906	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HMCHFCLE_01907	2.13e-140	nrdG	1.97.1.4	-	C	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMCHFCLE_01908	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HMCHFCLE_01909	6.84e-254	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HMCHFCLE_01910	1.83e-281	-	-	-	P	-	-	-	Transporter, CPA2 family
HMCHFCLE_01911	7.92e-162	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	PFAM Bacterial regulatory proteins, gntR family
HMCHFCLE_01912	7.15e-80	-	2.7.1.191	-	G	ko:K02793,ko:K19506	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HMCHFCLE_01913	1.29e-106	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HMCHFCLE_01914	1.21e-174	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HMCHFCLE_01915	9.72e-190	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HMCHFCLE_01916	1.9e-232	-	-	-	M	-	-	-	SIS domain
HMCHFCLE_01917	3.17e-142	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HMCHFCLE_01918	1.56e-200	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HMCHFCLE_01919	5.99e-50	-	-	-	-	-	-	-	-
HMCHFCLE_01920	5.32e-52	-	-	-	-	-	-	-	-
HMCHFCLE_01921	2.2e-223	-	-	-	S	-	-	-	CAAX protease self-immunity
HMCHFCLE_01922	5.4e-63	-	-	-	S	-	-	-	Putative heavy-metal-binding
HMCHFCLE_01923	1.96e-145	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HMCHFCLE_01924	1.59e-288	cshA	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	Belongs to the DEAD box helicase family
HMCHFCLE_01925	5.07e-62	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	bacterial (prokaryotic) histone like domain
HMCHFCLE_01926	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMCHFCLE_01927	5.51e-176	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HMCHFCLE_01928	4.43e-297	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMCHFCLE_01930	4.58e-156	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HMCHFCLE_01931	1.01e-156	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HMCHFCLE_01932	1.16e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMCHFCLE_01933	2.11e-174	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HMCHFCLE_01934	4.43e-95	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HMCHFCLE_01935	3.48e-145	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HMCHFCLE_01936	2.69e-20	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HMCHFCLE_01937	1.66e-39	-	-	-	K	-	-	-	Transcriptional regulator
HMCHFCLE_01939	2.83e-201	-	-	-	IQ	-	-	-	short chain dehydrogenase
HMCHFCLE_01940	4.9e-217	-	-	-	M	-	-	-	Domain of unknown function (DUF4349)
HMCHFCLE_01941	3.63e-115	-	-	-	K	ko:K03088	-	ko00000,ko03021	Putative ATPase subunit of terminase (gpP-like)
HMCHFCLE_01943	4.22e-124	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HMCHFCLE_01944	1.97e-116	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMCHFCLE_01945	4.22e-173	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HMCHFCLE_01946	1.07e-244	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HMCHFCLE_01947	1.14e-90	-	-	-	-	-	-	-	-
HMCHFCLE_01948	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA synthetase
HMCHFCLE_01949	2.24e-209	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Psort location Cytoplasmic, score
HMCHFCLE_01950	3.6e-30	-	-	-	-	-	-	-	-
HMCHFCLE_01951	1.44e-99	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01952	0.0	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	citrate synthase
HMCHFCLE_01953	1.34e-233	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
HMCHFCLE_01954	4.69e-161	-	-	-	-	-	-	-	-
HMCHFCLE_01955	7.82e-124	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMCHFCLE_01956	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
HMCHFCLE_01957	0.0	-	-	-	L	-	-	-	Resolvase, N-terminal domain protein
HMCHFCLE_01958	1.26e-22	-	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HMCHFCLE_01959	1.74e-79	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMCHFCLE_01960	2.51e-210	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMCHFCLE_01961	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMCHFCLE_01962	4.73e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HMCHFCLE_01963	9.36e-171	-	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HMCHFCLE_01964	2.48e-173	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HMCHFCLE_01965	6.95e-64	bcrA_2	-	-	V	ko:K01990,ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HMCHFCLE_01966	0.0	spoVD	3.4.16.4	-	M	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding Protein
HMCHFCLE_01967	1.98e-232	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HMCHFCLE_01968	4.84e-312	murA2	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HMCHFCLE_01969	1.28e-117	-	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
HMCHFCLE_01971	0.0	fusA2	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	translation elongation
HMCHFCLE_01972	7.84e-158	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	asparagine synthase (glutamine-hydrolyzing)
HMCHFCLE_01973	4.44e-293	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMCHFCLE_01974	4.61e-188	ttcA2	-	-	H	-	-	-	Belongs to the TtcA family
HMCHFCLE_01976	2.39e-98	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMCHFCLE_01977	6.32e-55	-	-	-	K	ko:K06284	-	ko00000,ko03000	Transcriptional regulator, AbrB family
HMCHFCLE_01978	2.6e-231	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
HMCHFCLE_01979	2.53e-215	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HMCHFCLE_01980	5.03e-157	-	-	-	KT	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HMCHFCLE_01981	4.39e-211	-	-	-	S	-	-	-	TraX protein
HMCHFCLE_01982	1.11e-55	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HMCHFCLE_01983	2.41e-200	-	-	-	-	-	-	-	-
HMCHFCLE_01984	4.91e-111	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01985	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMCHFCLE_01986	1.41e-19	-	-	-	-	-	-	-	-
HMCHFCLE_01987	4.38e-209	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMCHFCLE_01988	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMCHFCLE_01989	1.57e-95	-	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMCHFCLE_01990	9.22e-213	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HMCHFCLE_01991	6.18e-238	-	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase NAD-binding domain protein
HMCHFCLE_01992	6.16e-131	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HMCHFCLE_01993	6.31e-51	-	-	-	S	-	-	-	SPP1 phage holin
HMCHFCLE_01994	1.29e-31	-	-	-	-	-	-	-	-
HMCHFCLE_01995	3.72e-95	-	3.4.17.14	-	M	ko:K08640	-	ko00000,ko01000,ko01002,ko01011	Peptidase M15A
HMCHFCLE_01997	7.22e-149	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
HMCHFCLE_01998	6.42e-210	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase PanE/ApbA
HMCHFCLE_01999	3.03e-194	-	-	-	H	-	-	-	Leucine carboxyl methyltransferase
HMCHFCLE_02000	5.1e-32	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HMCHFCLE_02001	1.7e-132	-	-	-	Q	ko:K15256	-	ko00000,ko01000,ko03016	Methyltransferase domain protein
HMCHFCLE_02002	2.26e-98	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMCHFCLE_02003	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMCHFCLE_02005	5.22e-137	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HMCHFCLE_02006	4.26e-113	-	3.2.2.28	-	L	ko:K03649	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	UreE urease accessory protein, C-terminal domain
HMCHFCLE_02007	7.33e-220	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HMCHFCLE_02008	1.1e-199	-	-	-	S	ko:K07089	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HMCHFCLE_02009	5.28e-145	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMCHFCLE_02010	9.33e-153	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HMCHFCLE_02011	3.68e-180	-	-	-	U	-	-	-	domain, Protein
HMCHFCLE_02013	0.0	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HMCHFCLE_02014	4.25e-55	-	-	-	K	-	-	-	Helix-turn-helix domain
HMCHFCLE_02015	1.22e-222	-	-	-	D	-	-	-	Plasmid recombination enzyme
HMCHFCLE_02016	4.81e-60	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMCHFCLE_02017	5.99e-210	-	-	-	S	-	-	-	Phospholipase, patatin family
HMCHFCLE_02018	4.05e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMCHFCLE_02019	1.35e-283	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HMCHFCLE_02020	8.49e-79	-	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
HMCHFCLE_02021	2.64e-97	-	-	-	S	ko:K06923	-	ko00000	ATPase (AAA superfamily)
HMCHFCLE_02022	1.43e-190	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	pyridine
HMCHFCLE_02024	6.01e-123	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetolactate synthase small
HMCHFCLE_02025	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	acetolactate synthase large subunit