Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 17 | 29 | 33.62 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| DEOKGCEI_1 | 533804 | 534655 | rfbD | 0.0 | Capsule | Immune modulation | 95.07 | 100.00 | WP_014621820 |
| DEOKGCEI_1 | 1174705 | 1175436 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 94.81 | 100.00 | WP_011681176 |
| DEOKGCEI_1 | 537079 | 537794 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 94.55 | 99.86 | WP_011681442 |
| DEOKGCEI_1 | 1174705 | 1175436 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 94.54 | 100.00 | WP_011226048 |
| DEOKGCEI_1 | 1174705 | 1175436 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 94.13 | 100.00 | WP_011227248 |
| DEOKGCEI_1 | 538140 | 538910 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 92.48 | 99.23 | WP_011681440 |
| DEOKGCEI_1 | 534774 | 536032 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 92.38 | 99.92 | WP_011681445 |
| DEOKGCEI_1 | 1321278 | 1321871 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 91.75 | 100.00 | WP_011226149 |
| DEOKGCEI_1 | 1321278 | 1321871 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 91.58 | 100.00 | WP_011226149 |
| DEOKGCEI_1 | 1321278 | 1321871 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 91.58 | 100.00 | WP_011226149 |
| DEOKGCEI_1 | 1321871 | 1322740 | rfbA | 0.0 | Capsule | Immune modulation | 91.49 | 100.00 | WP_011681286 |
| DEOKGCEI_1 | 1055391 | 1057049 | fbp54 | 0.0 | FBPs | Adherence | 91.08 | 99.94 | WP_011227179 |
| DEOKGCEI_1 | 1175437 | 1176897 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 90.92 | 99.86 | WP_011681177 |
| DEOKGCEI_1 | 1175437 | 1176897 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 90.78 | 100.00 | WP_011226049 |
| DEOKGCEI_1 | 1175437 | 1176897 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 89.97 | 100.00 | WP_041827043 |
| DEOKGCEI_1 | 1174004 | 1174696 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 89.90 | 100.00 | WP_011226047 |
| DEOKGCEI_1 | 1174004 | 1174696 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 89.61 | 100.00 | WP_011227247 |
| DEOKGCEI_1 | 1174004 | 1174696 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.47 | 100.00 | WP_011681175 |
| DEOKGCEI_1 | 1497268 | 1498571 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.32 | 99.54 | WP_000022832 |
| DEOKGCEI_1 | 1711505 | 1712344 | cbpD | 0.0 | Autolysin | Exoenzyme | 87.87 | 99.88 | WP_011226733 |
| DEOKGCEI_1 | 210872 | 211885 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 85.48 | 99.90 | WP_002986042 |
| DEOKGCEI_1 | 904295 | 905056 | srtA | 0.0 | Sortase A | Exoenzyme | 85.21 | 99.74 | - |
| DEOKGCEI_1 | 1320029 | 1321075 | rfbB | 0.0 | Capsule | Immune modulation | 81.32 | 99.90 | WP_009659423 |
| DEOKGCEI_1 | 2000537 | 2001820 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.84 | 99.61 | WP_000107753 |
| DEOKGCEI_1 | 1173324 | 1173994 | STU_RS14635 | 1.26e-146 | Capsule | Immune modulation | 80.98 | 90.28 | WP_011226046 |
| DEOKGCEI_1 | 1173324 | 1173994 | STER_RS05305 | 5.87e-145 | Capsule | Immune modulation | 80.83 | 90.28 | WP_011681174 |
| DEOKGCEI_1 | 1173392 | 1173994 | STR_RS05250 | 5.96e-135 | Capsule | Immune modulation | 81.46 | 80.13 | WP_011227246 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| DEOKGCEI_1 | 901606 | 900623 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 96.95 | 100.00 | AAK75326 |
| DEOKGCEI_1 | 913192 | 914265 | MntE | 0.0 | manganese homeostasis | 96.09 | 99.72 | ABF32167 |
| DEOKGCEI_1 | 345941 | 343635 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 94.02 | 99.22 | AAK74619 |
| DEOKGCEI_1 | 1591643 | 1590675 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| DEOKGCEI_1 | 774007 | 772526 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.92 | 100.00 | ABJ54480 |
| DEOKGCEI_1 | 932251 | 934497 | metE | 0.0 | methionine biosynthesis enzymes | 92.79 | 100.00 | AAK74738 |
| DEOKGCEI_1 | 2116242 | 2115271 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 91.67 | 100.00 | ABF36968 |
| DEOKGCEI_1 | 1348113 | 1346383 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 89.95 | 100.00 | AAK34199 |
| DEOKGCEI_1 | 476285 | 477436 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.58 | 99.74 | AAL00050 |
| DEOKGCEI_1 | 519318 | 521306 | uvrB | 0.0 | excinuclease ABC, B subunit | 89.44 | 100.00 | AE014259_2 |
| DEOKGCEI_1 | 12858 | 14336 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.83 | 100.00 | ADE32434 |
| DEOKGCEI_1 | 1498571 | 1497270 | Eno | 0.0 | enolase | 86.44 | 99.77 | ABP90468 |
| DEOKGCEI_1 | 28208 | 30100 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.58 | 98.90 | ABP91129 |
| DEOKGCEI_1 | 2080512 | 2079421 | recA | 0.0 | DNA recombination and repair | 84.91 | 95.36 | AAL00560 |
| DEOKGCEI_1 | 937415 | 935706 | PGM | 0.0 | phosphoglucomutase | 84.76 | 99.65 | ACH87041 |
| DEOKGCEI_1 | 158795 | 157785 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| DEOKGCEI_1 | 1068109 | 1066748 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.46 | 99.56 | ABP90420 |
| DEOKGCEI_1 | 1514541 | 1513651 | bglB | 1.56e-177 | putative phospho--glucosidase | 87.88 | 99.66 | AAK33487 |
| DEOKGCEI_1 | 934687 | 935544 | metF | 7.09e-169 | methionine biosynthesis enzymes | 87.76 | 99.31 | AAK74739 |
| DEOKGCEI_1 | 977406 | 976468 | SP_0676 | 1.46e-167 | transcription facot | 81.47 | 97.20 | AAK74821 |
| DEOKGCEI_1 | 840780 | 841451 | rr01 | 4.59e-126 | response regulator | 84.82 | 99.56 | CAB54566 |
| DEOKGCEI_1 | 1211427 | 1210723 | covR | 2.23e-124 | responder protein | 85.53 | 100.00 | AAK71319 |
| DEOKGCEI_1 | 942080 | 942751 | ciaR | 2.69e-124 | two component system response regulator | 86.16 | 99.12 | AIK75708 |
| DEOKGCEI_1 | 942080 | 942748 | CiaR | 4.92e-124 | two-component response regulator | 87.44 | 99.55 | AAK74935 |
| DEOKGCEI_1 | 1843535 | 1842849 | CovR | 1.80e-119 | serves to repress GAS virulence factor-encoding genes | 82.10 | 100.00 | ACE75886 |
| DEOKGCEI_1 | 1211427 | 1210723 | walR | 2.38e-117 | DNA-binding response regulator | 80.00 | 100.00 | ANC99504 |
| DEOKGCEI_1 | 2078160 | 2077765 | SpxA2 | 2.11e-74 | transcriptional regulator | 91.67 | 100.00 | ERL21461 |
| DEOKGCEI_1 | 1079563 | 1079964 | SpxA1 | 1.36e-68 | transcriptional regulator | 82.09 | 100.00 | ERL19273 |
| DEOKGCEI_1 | 2021624 | 2021211 | GrpE | 3.94e-66 | protein grpE | 81.16 | 80.59 | ABP89267 |
| DEOKGCEI_1 | 2000370 | 1999879 | RopE (M5005_Spy_1611) | 1.04e-71 | probable DNA-directed RNA polymerase subunit delta | 82.93 | 85.86 | AAK34603 |
| DEOKGCEI_1 | 345941 | 343641 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.97 | 98.08 | MYN69560 |
| DEOKGCEI_1 | 122374 | 123393 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 85.88 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| DEOKGCEI_1 | 0.0 | 1.0 | 0.0 |
| DEOKGCEI_2 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| DEOKGCEI_2 | 4931 | 40697 | False | Siphoviridae | VOG0648, VOG0641, VOG0054, VOG8294, VOG0866, VOG0275, VOG1561, VOG4602, VOG6127, VOG4771, VOG8337, VOG7236, VOG0650, VOG0651, VOG5996, VOG0321, VOG0322, VOG4548, VOG6545, VOG4632, VOG4606, VOG0327, VOG0655, VOG6414, VOG0656, VOG0657, VOG0044, VOG0658, VOG0198, VOG4841, VOG4581, VOG8222, VOG4579, VOG1886, VOG1886, VOG0202, VOG4556, VOG4573, VOG4553, VOG0204, VOG0205, VOG0207, VOG4586, VOG0209, VOG4545, VOG6163 |
Phigaro v2.4.0 (Database: Jan. 2024 release)