Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 15 | 32 | 35.34 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| FOPMFGFP_100 | 13853 | 14446 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| FOPMFGFP_100 | 13853 | 14446 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| FOPMFGFP_100 | 13853 | 14446 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| FOPMFGFP_82 | 3445 | 5103 | fbp54 | 0.0 | FBPs | Adherence | 99.64 | 100.00 | WP_011227179 |
| FOPMFGFP_100 | 14446 | 15315 | rfbA | 0.0 | Capsule | Immune modulation | 99.19 | 100.00 | WP_011681286 |
| FOPMFGFP_100 | 49219 | 49980 | srtA | 0.0 | Sortase A | Exoenzyme | 98.42 | 100.00 | - |
| FOPMFGFP_98 | 19168 | 19962 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.11 | 100.25 | - |
| FOPMFGFP_96 | 1458 | 2189 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 97.95 | 100.00 | WP_011681176 |
| FOPMFGFP_42 | 6650 | 7612 | cbpD | 0.0 | Autolysin | Exoenzyme | 97.73 | 99.90 | WP_082302295 |
| FOPMFGFP_96 | 7 | 747 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.71 | 100.00 | WP_011226046 |
| FOPMFGFP_96 | 1458 | 2189 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.68 | 100.00 | WP_011226048 |
| FOPMFGFP_96 | 1458 | 2189 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 97.27 | 100.00 | WP_011227248 |
| FOPMFGFP_115 | 9 | 860 | rfbD | 0.0 | Capsule | Immune modulation | 97.07 | 100.00 | WP_014621820 |
| FOPMFGFP_96 | 7 | 747 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.03 | 100.00 | WP_011681174 |
| FOPMFGFP_96 | 2190 | 3650 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 96.65 | 100.00 | WP_011681177 |
| FOPMFGFP_96 | 12 | 747 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.47 | 98.13 | WP_011227246 |
| FOPMFGFP_96 | 2190 | 3650 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.44 | 100.21 | WP_011226049 |
| FOPMFGFP_96 | 757 | 1449 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 96.10 | 100.00 | WP_011227247 |
| FOPMFGFP_96 | 757 | 1449 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 96.10 | 100.00 | WP_011226047 |
| FOPMFGFP_96 | 2190 | 3650 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.76 | 100.21 | WP_041827043 |
| FOPMFGFP_96 | 757 | 1449 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.75 | 100.00 | WP_011681175 |
| FOPMFGFP_50 | 81114 | 82417 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.09 | 99.54 | WP_000022832 |
| FOPMFGFP_133 | 536 | 1546 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.69 | 99.70 | WP_002986042 |
| FOPMFGFP_100 | 12378 | 13424 | rfbB | 0.0 | Capsule | Immune modulation | 80.71 | 100.00 | WP_009659423 |
| FOPMFGFP_25 | 5229 | 6512 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.50 | 99.77 | WP_000107753 |
| FOPMFGFP_114 | 1 | 469 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.51 | 65.41 | WP_011681442 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| FOPMFGFP_100 | 52667 | 53650 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.51 | 100.00 | AAK75326 |
| FOPMFGFP_63 | 39020 | 40093 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| FOPMFGFP_126 | 2196 | 4499 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| FOPMFGFP_49 | 1887 | 2855 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| FOPMFGFP_106 | 17674 | 19155 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.51 | 100.00 | ABJ54480 |
| FOPMFGFP_65 | 691 | 2937 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| FOPMFGFP_6 | 14090 | 15082 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| FOPMFGFP_3 | 4482 | 5453 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| FOPMFGFP_119 | 16990 | 15839 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| FOPMFGFP_117 | 6740 | 4752 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| FOPMFGFP_100 | 36464 | 34734 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| FOPMFGFP_144 | 25797 | 24319 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| FOPMFGFP_50 | 81114 | 82415 | Eno | 0.0 | enolase | 86.44 | 99.77 | ABP90468 |
| FOPMFGFP_144 | 11060 | 9168 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| FOPMFGFP_65 | 5862 | 4153 | PGM | 0.0 | phosphoglucomutase | 83.36 | 99.65 | ACH87041 |
| FOPMFGFP_137 | 21455 | 22465 | pdh | 0.0 | pyruvate dehydrogenase | 82.79 | 99.70 | ABP91006 |
| FOPMFGFP_83 | 2629 | 1268 | mnmE | 0.0 | central tRNA-modifying GTPase | 81.80 | 99.56 | ABP90420 |
| FOPMFGFP_137 | 71776 | 69884 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| FOPMFGFP_50 | 66674 | 67564 | bglB | 6.92e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| FOPMFGFP_74 | 3862 | 2927 | SP_0676 | 4.43e-170 | transcription facot | 81.73 | 96.89 | AAK74821 |
| FOPMFGFP_65 | 3129 | 3986 | metF | 5.31e-167 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| FOPMFGFP_97 | 29337 | 28633 | covR | 6.74e-133 | responder protein | 85.53 | 100.00 | AAK71319 |
| FOPMFGFP_102 | 3538 | 2867 | rr01 | 9.95e-131 | response regulator | 84.38 | 99.56 | CAB54566 |
| FOPMFGFP_97 | 29337 | 28633 | walR | 9.06e-123 | DNA-binding response regulator | 81.28 | 100.00 | ANC99504 |
| FOPMFGFP_31 | 58400 | 59086 | CovR | 3.49e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| FOPMFGFP_6 | 15379 | 15774 | SpxA2 | 3.22e-76 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| FOPMFGFP_83 | 13984 | 14385 | SpxA1 | 5.57e-68 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| FOPMFGFP_35 | 13033 | 13320 | spr0479 | 1.43e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| FOPMFGFP_43 | 33466 | 33720 | spr1327 | 7.14e-46 | essential gene | 95.29 | 100.00 | AAL00131 |
| FOPMFGFP_141 | 2361 | 2624 | spr0175 | 3.78e-43 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| FOPMFGFP_141 | 3164 | 3454 | spr0177 | 2.21e-38 | essential gene | 81.00 | 98.02 | AAK98981 |
| FOPMFGFP_25 | 6670 | 7170 | RopE (M5005_Spy_1611) | 9.93e-77 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| FOPMFGFP_126 | 2196 | 4493 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.68 | 98.08 | MYN69560 |
| FOPMFGFP_137 | 57314 | 56295 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| FOPMFGFP_1 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_3 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_5 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_6 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_9 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_12 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_16 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_22 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_24 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_25 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_26 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_27 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_28 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_29 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_30 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_31 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_32 | 1.0 | 0.0 | 1.0 |
| FOPMFGFP_33 | 1.0 | 0.0 | 1.0 |
| FOPMFGFP_35 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_36 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_39 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_40 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_41 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_42 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_43 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_44 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_45 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_47 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_48 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_49 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_50 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_52 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_53 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_54 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_55 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_57 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_58 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_59 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_61 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_63 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_64 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_65 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_67 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_68 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_69 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_70 | 1.0 | 0.0 | 1.0 |
| FOPMFGFP_71 | 1.0 | 0.0 | 1.0 |
| FOPMFGFP_72 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_73 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_74 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_75 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_76 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_77 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_79 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_80 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_81 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_82 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_83 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_84 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_86 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_91 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_96 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_97 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_98 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_99 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_100 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_102 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_105 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_106 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_107 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_108 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_109 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_110 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_111 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_112 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_113 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_116 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_117 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_119 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_122 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_123 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_124 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_125 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_126 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_127 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_128 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_130 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_131 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_132 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_133 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_137 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_138 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_139 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_140 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_141 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_142 | 0.0 | 1.0 | 0.0 |
| FOPMFGFP_144 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)