Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 22 | 28 | 35.61 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| FMOMCKGE_1 | 1072399 | 1073268 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| FMOMCKGE_1 | 1071806 | 1072399 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| FMOMCKGE_1 | 1071806 | 1072399 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| FMOMCKGE_1 | 1280409 | 1281218 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.75 | 100.00 | WP_002948020 |
| FMOMCKGE_1 | 1071806 | 1072399 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| FMOMCKGE_1 | 823469 | 825127 | fbp54 | 0.0 | FBPs | Adherence | 99.64 | 100.00 | WP_011227179 |
| FMOMCKGE_1 | 1276350 | 1278132 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.44 | 99.89 | WP_011226325 |
| FMOMCKGE_1 | 1281202 | 1282158 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.27 | 100.00 | WP_011226328 |
| FMOMCKGE_1 | 939491 | 940222 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 99.18 | 100.00 | WP_011681176 |
| FMOMCKGE_1 | 1279204 | 1280409 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.17 | 100.00 | WP_011226326 |
| FMOMCKGE_1 | 1282155 | 1283303 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.13 | 100.00 | WP_041828290 |
| FMOMCKGE_1 | 1278129 | 1279184 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.05 | 100.00 | WP_002948022 |
| FMOMCKGE_1 | 39395 | 40234 | cbpD | 0.0 | Autolysin | Exoenzyme | 98.93 | 100.00 | WP_011226733 |
| FMOMCKGE_1 | 939491 | 940222 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011226048 |
| FMOMCKGE_1 | 939491 | 940222 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011227248 |
| FMOMCKGE_1 | 1283906 | 1284757 | rfbD | 0.0 | Capsule | Immune modulation | 97.77 | 100.00 | WP_014621820 |
| FMOMCKGE_1 | 940223 | 941683 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.67 | 100.00 | WP_011681177 |
| FMOMCKGE_1 | 1107165 | 1107926 | srtA | 0.0 | Sortase A | Exoenzyme | 97.64 | 100.00 | - |
| FMOMCKGE_1 | 940223 | 941683 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.51 | 100.21 | WP_011226049 |
| FMOMCKGE_1 | 940223 | 941683 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.69 | 100.21 | WP_041827043 |
| FMOMCKGE_1 | 936618 | 937983 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.17 | 99.85 | WP_011681173 |
| FMOMCKGE_1 | 938790 | 939482 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.09 | 100.00 | WP_011227247 |
| FMOMCKGE_1 | 938790 | 939482 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.09 | 100.00 | WP_011226047 |
| FMOMCKGE_1 | 938040 | 938780 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 94.20 | 100.00 | WP_011226046 |
| FMOMCKGE_1 | 1016911 | 1017692 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 94.09 | 99.62 | - |
| FMOMCKGE_1 | 938040 | 938780 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 94.06 | 100.00 | WP_011681174 |
| FMOMCKGE_1 | 936616 | 937983 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 93.93 | 100.00 | WP_011226045 |
| FMOMCKGE_1 | 938045 | 938780 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 93.61 | 98.13 | WP_011227246 |
| FMOMCKGE_1 | 938790 | 939482 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 93.36 | 100.00 | WP_011681175 |
| FMOMCKGE_1 | 558720 | 560023 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| FMOMCKGE_1 | 1572109 | 1573119 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.66 | 99.90 | WP_002986042 |
| FMOMCKGE_1 | 1070331 | 1071377 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| FMOMCKGE_1 | 115940 | 117223 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.50 | 99.77 | WP_000107753 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| FMOMCKGE_1 | 1110613 | 1111596 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| FMOMCKGE_1 | 667353 | 668426 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| FMOMCKGE_1 | 1452087 | 1454390 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| FMOMCKGE_1 | 476435 | 477403 | spr0084 | 0.0 | pathogenitcity related | 92.88 | 98.48 | AAK98888 |
| FMOMCKGE_1 | 1173922 | 1175403 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.71 | 100.00 | ABJ54480 |
| FMOMCKGE_1 | 689302 | 691548 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| FMOMCKGE_1 | 59026 | 60024 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| FMOMCKGE_1 | 22907 | 23878 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| FMOMCKGE_1 | 1336278 | 1335127 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| FMOMCKGE_1 | 1299709 | 1297721 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| FMOMCKGE_1 | 1094417 | 1092687 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| FMOMCKGE_1 | 1809305 | 1807827 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.83 | 100.00 | ADE32434 |
| FMOMCKGE_1 | 558720 | 560021 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| FMOMCKGE_1 | 1794570 | 1792678 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| FMOMCKGE_1 | 694473 | 692764 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| FMOMCKGE_1 | 1648256 | 1649266 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| FMOMCKGE_1 | 858674 | 857313 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| FMOMCKGE_1 | 1701909 | 1700017 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| FMOMCKGE_1 | 544281 | 545171 | bglB | 5.16e-178 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| FMOMCKGE_1 | 765244 | 764306 | SP_0676 | 2.31e-167 | transcription facot | 81.15 | 97.20 | AAK74821 |
| FMOMCKGE_1 | 691740 | 692597 | metF | 1.50e-164 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| FMOMCKGE_1 | 978737 | 978033 | covR | 4.30e-131 | responder protein | 85.53 | 100.00 | AAK71319 |
| FMOMCKGE_1 | 978737 | 978033 | walR | 1.81e-121 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| FMOMCKGE_1 | 698428 | 699096 | CiaR | 7.77e-120 | two-component response regulator | 84.75 | 99.55 | AAK74935 |
| FMOMCKGE_1 | 269205 | 269891 | CovR | 9.88e-118 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| FMOMCKGE_1 | 698428 | 699099 | ciaR | 1.42e-117 | two component system response regulator | 82.59 | 99.12 | AIK75708 |
| FMOMCKGE_1 | 60300 | 60674 | SpxA2 | 1.13e-69 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| FMOMCKGE_1 | 870090 | 870491 | SpxA1 | 3.69e-66 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| FMOMCKGE_1 | 117381 | 117881 | RopE (M5005_Spy_1611) | 4.83e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| FMOMCKGE_1 | 1452087 | 1454384 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| FMOMCKGE_1 | 1687502 | 1686483 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| FMOMCKGE_1 | 0.0 | 1.0 | 0.0 |
| FMOMCKGE_3 | 1.0 | 0.0 | 1.0 |
| FMOMCKGE_4 | 1.0 | 0.0 | 1.0 |
| FMOMCKGE_5 | 1.0 | 0.0 | 1.0 |
| FMOMCKGE_6 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)