Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 23 | 29 | 37.01 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| PFIBMOHG_1 | 1076314 | 1077183 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| PFIBMOHG_1 | 1075721 | 1076314 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| PFIBMOHG_1 | 1307253 | 1308221 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681443 |
| PFIBMOHG_1 | 37895 | 38734 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.88 | 100.00 | WP_011226733 |
| PFIBMOHG_1 | 1075721 | 1076314 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| PFIBMOHG_1 | 1075721 | 1076314 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| PFIBMOHG_1 | 845072 | 846730 | fbp54 | 0.0 | FBPs | Adherence | 99.64 | 100.00 | WP_011227179 |
| PFIBMOHG_1 | 1308239 | 1309216 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.28 | 100.00 | WP_011681444 |
| PFIBMOHG_1 | 1111446 | 1112207 | srtA | 0.0 | Sortase A | Exoenzyme | 99.21 | 100.00 | - |
| PFIBMOHG_1 | 1305420 | 1306190 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 99.09 | 99.10 | WP_011681440 |
| PFIBMOHG_1 | 951524 | 952255 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011681176 |
| PFIBMOHG_1 | 940108 | 941523 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 98.52 | 100.00 | WP_011681165 |
| PFIBMOHG_1 | 952256 | 953710 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 98.49 | 100.00 | WP_041827043 |
| PFIBMOHG_1 | 1306536 | 1307251 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.46 | 99.86 | WP_011681442 |
| PFIBMOHG_1 | 950073 | 950813 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 98.11 | 100.00 | WP_011681174 |
| PFIBMOHG_1 | 951524 | 952255 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.09 | 100.00 | WP_011226048 |
| PFIBMOHG_1 | 952256 | 953710 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 98.01 | 100.00 | WP_011226049 |
| PFIBMOHG_1 | 1020580 | 1021369 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 97.98 | 99.75 | - |
| PFIBMOHG_1 | 951524 | 952255 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 97.95 | 100.00 | WP_011227248 |
| PFIBMOHG_1 | 950073 | 950813 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.71 | 100.00 | WP_011226046 |
| PFIBMOHG_1 | 950078 | 950813 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.42 | 98.13 | WP_011227246 |
| PFIBMOHG_1 | 952256 | 953710 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.12 | 99.79 | WP_011681177 |
| PFIBMOHG_1 | 1310590 | 1311441 | rfbD | 0.0 | Capsule | Immune modulation | 97.07 | 100.00 | WP_014621820 |
| PFIBMOHG_1 | 1309213 | 1310471 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 96.35 | 99.92 | WP_011681445 |
| PFIBMOHG_1 | 950823 | 951515 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.53 | 99.86 | WP_011226047 |
| PFIBMOHG_1 | 950823 | 951515 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.24 | 100.00 | WP_011227247 |
| PFIBMOHG_1 | 948649 | 950016 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 95.10 | 100.00 | WP_011226045 |
| PFIBMOHG_1 | 948651 | 950016 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.07 | 99.85 | WP_011681173 |
| PFIBMOHG_1 | 950823 | 951515 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 91.20 | 100.00 | WP_011681175 |
| PFIBMOHG_1 | 582582 | 583885 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| PFIBMOHG_1 | 1584076 | 1585086 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.55 | 99.90 | WP_002986042 |
| PFIBMOHG_1 | 132366 | 133649 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.68 | 99.61 | WP_000107753 |
| PFIBMOHG_1 | 1074246 | 1075292 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| PFIBMOHG_1 | 937740 | 938326 | SPD_RS01775 | 2.28e-143 | Capsule | Immune modulation | 82.65 | 96.70 | WP_001819836 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| PFIBMOHG_1 | 1114894 | 1115877 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| PFIBMOHG_1 | 690044 | 691117 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| PFIBMOHG_1 | 498949 | 499917 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| PFIBMOHG_1 | 1475029 | 1477332 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.10 | 99.22 | AAK74619 |
| PFIBMOHG_1 | 709893 | 712139 | metE | 0.0 | methionine biosynthesis enzymes | 91.72 | 100.00 | AAK74738 |
| PFIBMOHG_1 | 1197198 | 1198679 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.50 | 100.00 | ABJ54480 |
| PFIBMOHG_1 | 61941 | 62939 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| PFIBMOHG_1 | 21413 | 22384 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| PFIBMOHG_1 | 1360530 | 1359379 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| PFIBMOHG_1 | 1324739 | 1322751 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| PFIBMOHG_1 | 1098697 | 1096967 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.52 | 100.00 | AAK34199 |
| PFIBMOHG_1 | 1771737 | 1770259 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| PFIBMOHG_1 | 582582 | 583883 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| PFIBMOHG_1 | 1756514 | 1754622 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| PFIBMOHG_1 | 715064 | 713355 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| PFIBMOHG_1 | 1621514 | 1622524 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| PFIBMOHG_1 | 874661 | 873300 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| PFIBMOHG_1 | 1673533 | 1671641 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| PFIBMOHG_1 | 568145 | 569035 | bglB | 1.28e-178 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| PFIBMOHG_1 | 791628 | 790690 | SP_0676 | 2.27e-167 | transcription facot | 81.15 | 97.20 | AAK74821 |
| PFIBMOHG_1 | 712331 | 713188 | metF | 1.47e-164 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| PFIBMOHG_1 | 990490 | 989786 | covR | 4.21e-131 | responder protein | 85.53 | 100.00 | AAK71319 |
| PFIBMOHG_1 | 1169098 | 1168427 | rr01 | 4.02e-125 | response regulator | 84.38 | 99.56 | CAB54566 |
| PFIBMOHG_1 | 990490 | 989786 | walR | 1.77e-121 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| PFIBMOHG_1 | 286502 | 287188 | CovR | 9.68e-118 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| PFIBMOHG_1 | 719018 | 719686 | CiaR | 1.94e-117 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| PFIBMOHG_1 | 719018 | 719689 | ciaR | 1.91e-115 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| PFIBMOHG_1 | 63215 | 63589 | SpxA2 | 1.11e-69 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| PFIBMOHG_1 | 886019 | 886420 | SpxA1 | 3.62e-66 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| PFIBMOHG_1 | 133807 | 134307 | RopE (M5005_Spy_1611) | 4.73e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| PFIBMOHG_1 | 1475029 | 1477326 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| PFIBMOHG_1 | 1658367 | 1657348 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| PFIBMOHG_1 | 0.0 | 1.0 | 0.0 |
| PFIBMOHG_6 | 1.0 | 0.0 | 1.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)