Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 24 | 30 | 38.42 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| IJELDABO_1 | 1671636 | 1672487 | rfbD | 0.0 | Capsule | Immune modulation | 95.19 | 100.00 | WP_014621820 |
| IJELDABO_1 | 1054296 | 1055036 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 95.01 | 100.00 | WP_011681174 |
| IJELDABO_1 | 1054296 | 1055036 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 94.33 | 100.00 | WP_011226046 |
| IJELDABO_1 | 1051393 | 1052853 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 94.11 | 100.14 | WP_011226049 |
| IJELDABO_1 | 1051393 | 1052853 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 94.05 | 99.93 | WP_011681177 |
| IJELDABO_1 | 1055093 | 1056460 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.01 | 100.00 | WP_011226045 |
| IJELDABO_1 | 1054296 | 1055031 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 93.75 | 98.13 | WP_011227246 |
| IJELDABO_1 | 1669264 | 1670535 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 93.71 | 99.76 | WP_011226331 |
| IJELDABO_1 | 1055093 | 1056458 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 93.70 | 99.85 | WP_011681173 |
| IJELDABO_1 | 1668306 | 1669261 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 93.41 | 94.56 | WP_011226330 |
| IJELDABO_1 | 1051393 | 1052853 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 93.22 | 100.14 | WP_041827043 |
| IJELDABO_1 | 1659654 | 1661438 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 92.61 | 99.94 | WP_011226325 |
| IJELDABO_1 | 1664488 | 1665444 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 92.48 | 100.00 | WP_011226328 |
| IJELDABO_1 | 1665441 | 1666589 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 92.34 | 100.00 | WP_041828290 |
| IJELDABO_1 | 1663695 | 1664504 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 92.23 | 99.88 | WP_002948020 |
| IJELDABO_1 | 1662490 | 1663695 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 92.12 | 100.00 | WP_011226326 |
| IJELDABO_1 | 1052854 | 1053585 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 91.53 | 100.00 | WP_011226048 |
| IJELDABO_1 | 1661435 | 1662469 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 91.29 | 99.15 | WP_002948022 |
| IJELDABO_1 | 1052854 | 1053585 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 91.12 | 100.00 | WP_011681176 |
| IJELDABO_1 | 883068 | 883661 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 91.08 | 100.00 | WP_011226149 |
| IJELDABO_1 | 38981 | 39820 | cbpD | 0.0 | Autolysin | Exoenzyme | 90.95 | 100.00 | WP_011226733 |
| IJELDABO_1 | 883068 | 883661 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 90.91 | 100.00 | WP_011226149 |
| IJELDABO_1 | 883068 | 883661 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 90.91 | 100.00 | WP_011226149 |
| IJELDABO_1 | 1160498 | 1162156 | fbp54 | 0.0 | FBPs | Adherence | 90.84 | 99.94 | WP_011227179 |
| IJELDABO_1 | 1052854 | 1053585 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 90.57 | 100.00 | WP_011227248 |
| IJELDABO_1 | 882199 | 883068 | rfbA | 0.0 | Capsule | Immune modulation | 90.46 | 100.00 | WP_011681286 |
| IJELDABO_1 | 1979178 | 1980188 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 88.55 | 99.80 | WP_002986042 |
| IJELDABO_1 | 670714 | 672017 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.24 | 99.54 | WP_000022832 |
| IJELDABO_1 | 1053594 | 1054286 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 88.04 | 99.86 | WP_011227247 |
| IJELDABO_1 | 1053594 | 1054286 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 88.04 | 99.86 | WP_011226047 |
| IJELDABO_1 | 1053594 | 1054286 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 87.46 | 99.86 | WP_011681175 |
| IJELDABO_1 | 1299058 | 1299819 | srtA | 0.0 | Sortase A | Exoenzyme | 84.40 | 99.87 | - |
| IJELDABO_1 | 883932 | 884978 | rfbB | 0.0 | Capsule | Immune modulation | 83.98 | 99.81 | WP_002263087 |
| IJELDABO_1 | 195463 | 196746 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.84 | 99.61 | WP_000107753 |
| IJELDABO_1 | 1065599 | 1066184 | SPD_RS01775 | 2.18e-139 | Capsule | Immune modulation | 82.28 | 96.53 | WP_001819836 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| IJELDABO_1 | 1302509 | 1303492 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 96.65 | 100.00 | AAK75326 |
| IJELDABO_1 | 1290921 | 1289848 | MntE | 0.0 | manganese homeostasis | 95.53 | 99.72 | ABF32167 |
| IJELDABO_1 | 1854972 | 1857278 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 94.41 | 99.22 | AAK74619 |
| IJELDABO_1 | 1443543 | 1445024 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 93.32 | 100.00 | ABJ54480 |
| IJELDABO_1 | 581879 | 582847 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| IJELDABO_1 | 1271859 | 1269613 | metE | 0.0 | methionine biosynthesis enzymes | 92.52 | 100.00 | AAK74738 |
| IJELDABO_1 | 24558 | 25529 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 91.67 | 100.00 | ABF36968 |
| IJELDABO_1 | 856819 | 858549 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 89.95 | 100.00 | AAK34199 |
| IJELDABO_1 | 1684701 | 1682713 | uvrB | 0.0 | excinuclease ABC, B subunit | 89.44 | 100.00 | AE014259_2 |
| IJELDABO_1 | 1713055 | 1711904 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| IJELDABO_1 | 2177945 | 2176467 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.83 | 100.00 | ADE32434 |
| IJELDABO_1 | 670714 | 672015 | Eno | 0.0 | enolase | 86.44 | 99.77 | ABP90468 |
| IJELDABO_1 | 2162611 | 2160719 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.58 | 98.90 | ABP91129 |
| IJELDABO_1 | 1266694 | 1268403 | PGM | 0.0 | phosphoglucomutase | 85.11 | 99.65 | ACH87041 |
| IJELDABO_1 | 61310 | 62401 | recA | 0.0 | DNA recombination and repair | 84.64 | 95.36 | AAL00560 |
| IJELDABO_1 | 2029766 | 2030776 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| IJELDABO_1 | 1146733 | 1148094 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.46 | 99.56 | ABP90420 |
| IJELDABO_1 | 656295 | 657185 | bglB | 2.38e-176 | putative phospho--glucosidase | 87.20 | 99.66 | AAK33487 |
| IJELDABO_1 | 1269426 | 1268569 | metF | 5.52e-168 | methionine biosynthesis enzymes | 87.76 | 99.31 | AAK74739 |
| IJELDABO_1 | 1227424 | 1228374 | SP_0676 | 5.65e-168 | transcription facot | 81.07 | 98.45 | AAK74821 |
| IJELDABO_1 | 1177998 | 1177213 | pnuC | 1.58e-148 | NAD salvage pathway importer | 87.02 | 97.40 | AAK75931 |
| IJELDABO_1 | 1373957 | 1373286 | rr01 | 4.70e-126 | response regulator | 84.82 | 99.56 | CAB54566 |
| IJELDABO_1 | 1005728 | 1006432 | covR | 9.76e-126 | responder protein | 85.53 | 100.00 | AAK71319 |
| IJELDABO_1 | 1262727 | 1262056 | ciaR | 2.10e-124 | two component system response regulator | 86.16 | 99.12 | AIK75708 |
| IJELDABO_1 | 1262727 | 1262059 | CiaR | 3.88e-124 | two-component response regulator | 87.44 | 99.55 | AAK74935 |
| IJELDABO_1 | 1005728 | 1006432 | walR | 2.22e-119 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| IJELDABO_1 | 339956 | 340642 | CovR | 4.79e-119 | serves to repress GAS virulence factor-encoding genes | 81.66 | 100.00 | ACE75886 |
| IJELDABO_1 | 62575 | 62970 | SpxA2 | 2.16e-74 | transcriptional regulator | 91.67 | 100.00 | ERL21461 |
| IJELDABO_1 | 1135266 | 1134865 | SpxA1 | 4.49e-69 | transcriptional regulator | 82.84 | 100.00 | ERL19273 |
| IJELDABO_1 | 176038 | 176451 | GrpE | 1.70e-66 | protein grpE | 81.88 | 80.59 | ABP89267 |
| IJELDABO_1 | 196913 | 197404 | RopE (M5005_Spy_1611) | 1.06e-71 | probable DNA-directed RNA polymerase subunit delta | 82.93 | 85.86 | AAK34603 |
| IJELDABO_1 | 1854972 | 1857272 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.09 | 98.08 | MYN69560 |
| IJELDABO_1 | 2066204 | 2065185 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 97.35 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| IJELDABO_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| IJELDABO_1 | 674747 | 710560 | False | Siphoviridae | VOG0743, VOG3622, VOG3478, VOG0651, VOG0083, VOG0322, VOG7263, VOG4548, VOG7264, VOG4693, VOG7265, VOG0655, VOG3468, VOG0656, VOG0152, VOG0657, VOG0044, VOG0658, VOG4987, VOG0796, VOG4544, VOG0691, VOG0692, VOG4555, VOG4711, VOG5872, VOG0695, VOG0696, VOG0697, VOG0698, VOG8357, VOG0701, VOG3636, VOG4633, VOG4828, VOG0641, VOG0054, VOG5034, VOG7557 |
Phigaro v2.4.0 (Database: Jan. 2024 release)