Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 25 | 33 | 41.40 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| BOIHMMHA_32 | 1520 | 2113 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| BOIHMMHA_4 | 114 | 1574 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 99.93 | 100.00 | WP_011681177 |
| BOIHMMHA_32 | 1520 | 2113 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| BOIHMMHA_78 | 13371 | 14180 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.75 | 100.00 | WP_002948020 |
| BOIHMMHA_32 | 2113 | 2982 | rfbA | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011681286 |
| BOIHMMHA_32 | 1520 | 2113 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| BOIHMMHA_21 | 12951 | 14609 | fbp54 | 0.0 | FBPs | Adherence | 99.64 | 100.00 | WP_011227179 |
| BOIHMMHA_78 | 14164 | 15120 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226328 |
| BOIHMMHA_28 | 2239 | 3382 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 99.56 | 100.00 | - |
| BOIHMMHA_78 | 9298 | 11082 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.44 | 100.00 | WP_011226325 |
| BOIHMMHA_78 | 12166 | 13371 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.17 | 100.00 | WP_011226326 |
| BOIHMMHA_78 | 21307 | 22158 | rfbD | 0.0 | Capsule | Immune modulation | 99.06 | 100.00 | WP_014621820 |
| BOIHMMHA_4 | 1575 | 2306 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.91 | 100.00 | WP_011681176 |
| BOIHMMHA_37 | 19440 | 20408 | cbpD | 0.0 | Autolysin | Exoenzyme | 98.86 | 100.00 | WP_082302295 |
| BOIHMMHA_36 | 24807 | 25568 | srtA | 0.0 | Sortase A | Exoenzyme | 98.82 | 100.00 | - |
| BOIHMMHA_78 | 15117 | 16265 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 98.78 | 100.00 | WP_041828290 |
| BOIHMMHA_4 | 1575 | 2306 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011227248 |
| BOIHMMHA_4 | 1575 | 2306 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_011226048 |
| BOIHMMHA_4 | 12323 | 13738 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 98.23 | 100.00 | WP_011681165 |
| BOIHMMHA_4 | 3017 | 3757 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 98.11 | 100.00 | WP_011226046 |
| BOIHMMHA_4 | 3017 | 3757 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.71 | 100.00 | WP_011681174 |
| BOIHMMHA_4 | 114 | 1574 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 97.40 | 100.21 | WP_011226049 |
| BOIHMMHA_4 | 3017 | 3752 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.15 | 98.13 | WP_011227246 |
| BOIHMMHA_4 | 3814 | 5181 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 97.00 | 100.00 | WP_011226045 |
| BOIHMMHA_4 | 114 | 1574 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.85 | 100.21 | WP_041827043 |
| BOIHMMHA_4 | 2315 | 3007 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.38 | 100.00 | WP_011227247 |
| BOIHMMHA_4 | 2315 | 3007 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.38 | 100.00 | WP_011226047 |
| BOIHMMHA_78 | 11079 | 12146 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 95.27 | 101.14 | WP_002948022 |
| BOIHMMHA_4 | 3814 | 5179 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.58 | 99.85 | WP_011681173 |
| BOIHMMHA_4 | 2315 | 3007 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 90.48 | 100.00 | WP_011681175 |
| BOIHMMHA_78 | 18930 | 20204 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 89.42 | 99.92 | WP_011226331 |
| BOIHMMHA_9 | 38760 | 40063 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.02 | 99.46 | WP_000022832 |
| BOIHMMHA_11 | 26 | 1036 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.54 | 99.41 | WP_002986042 |
| BOIHMMHA_72 | 2124 | 3407 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.81 | 99.77 | WP_000107753 |
| BOIHMMHA_32 | 45 | 1091 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| BOIHMMHA_4 | 15558 | 16141 | SPD_RS01775 | 9.53e-154 | Capsule | Immune modulation | 83.59 | 96.20 | WP_001819836 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| BOIHMMHA_36 | 22120 | 21137 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| BOIHMMHA_42 | 6612 | 7685 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| BOIHMMHA_80 | 130154 | 132457 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| BOIHMMHA_8 | 12300 | 13268 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| BOIHMMHA_39 | 8212 | 10458 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| BOIHMMHA_20 | 12554 | 11073 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.70 | 100.00 | ABJ54480 |
| BOIHMMHA_5 | 19755 | 20753 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| BOIHMMHA_55 | 15232 | 14261 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| BOIHMMHA_80 | 16147 | 14996 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.06 | 99.74 | AAL00050 |
| BOIHMMHA_78 | 35335 | 33347 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| BOIHMMHA_36 | 38319 | 40049 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| BOIHMMHA_14 | 26927 | 28405 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| BOIHMMHA_9 | 38760 | 40061 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| BOIHMMHA_14 | 42116 | 44008 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| BOIHMMHA_39 | 13383 | 11674 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| BOIHMMHA_1 | 17995 | 19005 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| BOIHMMHA_21 | 36463 | 35102 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| BOIHMMHA_1 | 68339 | 66447 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| BOIHMMHA_9 | 24324 | 25214 | bglB | 1.73e-179 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| BOIHMMHA_70 | 1144 | 206 | SP_0676 | 4.30e-169 | transcription facot | 81.15 | 97.20 | AAK74821 |
| BOIHMMHA_39 | 10650 | 11507 | metF | 1.56e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| BOIHMMHA_6 | 29751 | 30455 | covR | 1.27e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| BOIHMMHA_20 | 31529 | 32200 | rr01 | 9.64e-126 | response regulator | 83.93 | 99.56 | CAB54566 |
| BOIHMMHA_6 | 29751 | 30455 | walR | 5.37e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| BOIHMMHA_10 | 7607 | 6921 | CovR | 1.28e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| BOIHMMHA_39 | 17337 | 18005 | CiaR | 2.08e-119 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| BOIHMMHA_39 | 17337 | 18008 | ciaR | 2.05e-117 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| BOIHMMHA_5 | 21029 | 21403 | SpxA2 | 1.33e-71 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| BOIHMMHA_21 | 47825 | 48226 | SpxA1 | 1.35e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| BOIHMMHA_24 | 13624 | 13911 | spr0479 | 2.97e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| BOIHMMHA_37 | 61290 | 61544 | spr1327 | 9.96e-46 | essential gene | 95.29 | 100.00 | AAL00131 |
| BOIHMMHA_18 | 20859 | 20596 | spr0175 | 1.40e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| BOIHMMHA_18 | 20032 | 19766 | spr0177 | 3.05e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| BOIHMMHA_72 | 3565 | 4065 | RopE (M5005_Spy_1611) | 1.66e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| BOIHMMHA_80 | 130154 | 132451 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| BOIHMMHA_1 | 53879 | 52860 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| BOIHMMHA_1 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_2 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_4 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_5 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_6 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_7 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_8 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_9 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_10 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_11 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_12 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_13 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_14 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_16 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_18 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_19 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_20 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_21 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_22 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_23 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_24 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_25 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_26 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_28 | 1.0 | 0.0 | 1.0 |
| BOIHMMHA_29 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_31 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_32 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_33 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_34 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_35 | 1.0 | 0.0 | 1.0 |
| BOIHMMHA_36 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_37 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_38 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_39 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_40 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_42 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_43 | 1.0 | 0.0 | 1.0 |
| BOIHMMHA_44 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_45 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_46 | 1.0 | 0.0 | 1.0 |
| BOIHMMHA_47 | 1.0 | 0.0 | 1.0 |
| BOIHMMHA_51 | 1.0 | 0.0 | 1.0 |
| BOIHMMHA_52 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_53 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_54 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_55 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_56 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_57 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_59 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_60 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_62 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_63 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_64 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_65 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_66 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_67 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_68 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_69 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_70 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_71 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_72 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_73 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_74 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_75 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_76 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_77 | 1.0 | 0.0 | 1.0 |
| BOIHMMHA_78 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_79 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_80 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_81 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_82 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_84 | 0.0 | 1.0 | 0.0 |
| BOIHMMHA_85 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)