Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 18 | 33 | 37.59 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| HFNBABML_49 | 9812 | 10681 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| HFNBABML_49 | 9219 | 9812 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| HFNBABML_5 | 30579 | 31547 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681443 |
| HFNBABML_49 | 9219 | 9812 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| HFNBABML_49 | 9219 | 9812 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| HFNBABML_20 | 1486 | 3144 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| HFNBABML_14 | 1089 | 2231 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 99.47 | 99.83 | - |
| HFNBABML_5 | 31565 | 32542 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.39 | 100.00 | WP_011681444 |
| HFNBABML_49 | 44581 | 45342 | srtA | 0.0 | Sortase A | Exoenzyme | 98.82 | 100.00 | - |
| HFNBABML_15 | 63414 | 64868 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 98.49 | 100.00 | WP_041827043 |
| HFNBABML_5 | 29862 | 30578 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.19 | 100.00 | WP_011681442 |
| HFNBABML_15 | 63414 | 64868 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 97.94 | 100.00 | WP_011226049 |
| HFNBABML_57 | 46640 | 47599 | cbpD | 0.0 | Autolysin | Exoenzyme | 97.42 | 99.90 | WP_082302295 |
| HFNBABML_5 | 33916 | 34767 | rfbD | 0.0 | Capsule | Immune modulation | 97.07 | 100.00 | WP_014621820 |
| HFNBABML_15 | 63414 | 64868 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 96.92 | 99.79 | WP_011681177 |
| HFNBABML_5 | 28746 | 29516 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 96.89 | 99.10 | WP_011681440 |
| HFNBABML_5 | 32539 | 33797 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 96.51 | 99.92 | WP_011681445 |
| HFNBABML_21 | 21840 | 23143 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| HFNBABML_30 | 928 | 1938 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.46 | 99.80 | WP_002986042 |
| HFNBABML_46 | 2572 | 3855 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| HFNBABML_49 | 7744 | 8790 | rfbB | 0.0 | Capsule | Immune modulation | 80.52 | 100.00 | WP_009659423 |
| HFNBABML_15 | 67252 | 67835 | SPD_RS01775 | 1.92e-151 | Capsule | Immune modulation | 83.42 | 96.20 | WP_001819836 |
| HFNBABML_15 | 64869 | 65333 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.71 | 63.52 | WP_011227248 |
| HFNBABML_15 | 64869 | 65333 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 97.85 | 63.52 | WP_011681176 |
| HFNBABML_15 | 64869 | 65333 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.20 | 63.52 | WP_011226048 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| HFNBABML_49 | 48029 | 49012 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| HFNBABML_52 | 13760 | 12687 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| HFNBABML_21 | 106780 | 105812 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| HFNBABML_60 | 2289 | 4592 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| HFNBABML_50 | 13145 | 11664 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| HFNBABML_15 | 6973 | 9219 | metE | 0.0 | methionine biosynthesis enzymes | 91.72 | 100.00 | AAK74738 |
| HFNBABML_59 | 2029 | 1031 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| HFNBABML_61 | 27434 | 26463 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| HFNBABML_5 | 75803 | 74652 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.06 | 99.74 | AAL00050 |
| HFNBABML_5 | 47806 | 45818 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| HFNBABML_49 | 31833 | 30103 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| HFNBABML_39 | 27029 | 28507 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| HFNBABML_21 | 23143 | 21842 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| HFNBABML_39 | 42218 | 44110 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| HFNBABML_23 | 2010 | 301 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| HFNBABML_16 | 2137 | 1127 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| HFNBABML_32 | 1493 | 132 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| HFNBABML_44 | 48445 | 46553 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| HFNBABML_21 | 37578 | 36688 | bglB | 8.50e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| HFNBABML_29 | 39803 | 40738 | SP_0676 | 1.76e-169 | transcription facot | 81.73 | 96.89 | AAK74821 |
| HFNBABML_15 | 9411 | 10268 | metF | 5.75e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| HFNBABML_15 | 26591 | 27295 | covR | 1.65e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| HFNBABML_50 | 32122 | 32793 | rr01 | 9.81e-126 | response regulator | 83.93 | 99.56 | CAB54566 |
| HFNBABML_15 | 26591 | 27295 | walR | 6.94e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| HFNBABML_27 | 4145 | 4831 | CovR | 6.58e-120 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| HFNBABML_23 | 5964 | 6632 | CiaR | 8.47e-120 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| HFNBABML_23 | 5964 | 6635 | ciaR | 8.33e-118 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| HFNBABML_59 | 755 | 381 | SpxA2 | 8.99e-72 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| HFNBABML_32 | 12852 | 13253 | SpxA1 | 1.30e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| HFNBABML_45 | 13935 | 14222 | spr0479 | 3.02e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| HFNBABML_57 | 5753 | 5499 | spr1327 | 1.30e-44 | essential gene | 94.12 | 100.00 | AAL00131 |
| HFNBABML_39 | 84808 | 84545 | spr0175 | 3.81e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| HFNBABML_39 | 83981 | 83715 | spr0177 | 8.33e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| HFNBABML_46 | 4013 | 4513 | RopE (M5005_Spy_1611) | 1.69e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| HFNBABML_60 | 2289 | 4586 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| HFNBABML_44 | 33984 | 32965 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| HFNBABML_2 | 0.0 | 1.0 | 0.0 |
| HFNBABML_4 | 0.0 | 1.0 | 0.0 |
| HFNBABML_5 | 0.0 | 1.0 | 0.0 |
| HFNBABML_6 | 0.0 | 1.0 | 0.0 |
| HFNBABML_8 | 0.0 | 1.0 | 0.0 |
| HFNBABML_9 | 1.0 | 0.0 | 1.0 |
| HFNBABML_10 | 0.0 | 1.0 | 0.0 |
| HFNBABML_11 | 0.0 | 1.0 | 0.0 |
| HFNBABML_14 | 1.0 | 0.0 | 1.0 |
| HFNBABML_15 | 0.0 | 1.0 | 0.0 |
| HFNBABML_16 | 0.0 | 1.0 | 0.0 |
| HFNBABML_17 | 0.0 | 1.0 | 0.0 |
| HFNBABML_19 | 0.0 | 1.0 | 0.0 |
| HFNBABML_20 | 0.0 | 1.0 | 0.0 |
| HFNBABML_21 | 0.0 | 1.0 | 0.0 |
| HFNBABML_23 | 0.0 | 1.0 | 0.0 |
| HFNBABML_24 | 0.0 | 1.0 | 0.0 |
| HFNBABML_25 | 0.0 | 1.0 | 0.0 |
| HFNBABML_26 | 1.0 | 0.0 | 1.0 |
| HFNBABML_27 | 0.0 | 1.0 | 0.0 |
| HFNBABML_28 | 0.0 | 1.0 | 0.0 |
| HFNBABML_29 | 0.0 | 1.0 | 0.0 |
| HFNBABML_30 | 0.0 | 1.0 | 0.0 |
| HFNBABML_31 | 0.0 | 1.0 | 0.0 |
| HFNBABML_32 | 0.0 | 1.0 | 0.0 |
| HFNBABML_33 | 0.0 | 1.0 | 0.0 |
| HFNBABML_35 | 0.0 | 1.0 | 0.0 |
| HFNBABML_39 | 0.0 | 1.0 | 0.0 |
| HFNBABML_40 | 0.0 | 1.0 | 0.0 |
| HFNBABML_41 | 0.0 | 1.0 | 0.0 |
| HFNBABML_43 | 0.0 | 1.0 | 0.0 |
| HFNBABML_44 | 0.0 | 1.0 | 0.0 |
| HFNBABML_45 | 0.0 | 1.0 | 0.0 |
| HFNBABML_46 | 0.0 | 1.0 | 0.0 |
| HFNBABML_47 | 0.0 | 1.0 | 0.0 |
| HFNBABML_48 | 0.0 | 1.0 | 0.0 |
| HFNBABML_49 | 0.0 | 1.0 | 0.0 |
| HFNBABML_50 | 0.0 | 1.0 | 0.0 |
| HFNBABML_52 | 0.0 | 1.0 | 0.0 |
| HFNBABML_53 | 0.0 | 1.0 | 0.0 |
| HFNBABML_55 | 0.0 | 1.0 | 0.0 |
| HFNBABML_56 | 1.0 | 0.0 | 1.0 |
| HFNBABML_57 | 0.0 | 1.0 | 0.0 |
| HFNBABML_59 | 0.0 | 1.0 | 0.0 |
| HFNBABML_60 | 0.0 | 1.0 | 0.0 |
| HFNBABML_61 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)