Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 23 | 33 | 40.22 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| OBMDHJLN_41 | 140575 | 141290 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 96.09 | 99.86 | WP_011681442 |
| OBMDHJLN_41 | 143714 | 144565 | rfbD | 0.0 | Capsule | Immune modulation | 94.95 | 100.00 | WP_014621820 |
| OBMDHJLN_39 | 1806 | 2537 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 94.67 | 100.00 | WP_011227248 |
| OBMDHJLN_41 | 135355 | 136161 | STER_RS07060 | 0.0 | Capsule | Immune modulation | 94.18 | 100.00 | WP_011681437 |
| OBMDHJLN_41 | 135355 | 136161 | STR_RS06900 | 0.0 | Capsule | Immune modulation | 94.18 | 100.00 | WP_011227429 |
| OBMDHJLN_39 | 1806 | 2537 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 93.99 | 100.00 | WP_011226048 |
| OBMDHJLN_39 | 1806 | 2537 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 93.72 | 100.00 | WP_011681176 |
| OBMDHJLN_41 | 139455 | 140229 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 93.29 | 99.74 | WP_011681440 |
| OBMDHJLN_41 | 142337 | 143595 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 92.46 | 99.92 | WP_011681445 |
| OBMDHJLN_41 | 134153 | 135355 | STER_RS07055 | 0.0 | Capsule | Immune modulation | 92.35 | 100.00 | WP_011681436 |
| OBMDHJLN_41 | 134153 | 135355 | STR_RS06895 | 0.0 | Capsule | Immune modulation | 92.10 | 100.00 | WP_011227428 |
| OBMDHJLN_39 | 345 | 1805 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 91.26 | 99.86 | WP_011681177 |
| OBMDHJLN_41 | 136161 | 137102 | STER_RS07065 | 0.0 | Capsule | Immune modulation | 91.08 | 100.00 | WP_011681438 |
| OBMDHJLN_22 | 146728 | 147321 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 91.08 | 100.00 | WP_011226149 |
| OBMDHJLN_41 | 136161 | 137102 | STR_RS06905 | 0.0 | Capsule | Immune modulation | 90.98 | 100.00 | WP_011227430 |
| OBMDHJLN_39 | 119611 | 121269 | fbp54 | 0.0 | FBPs | Adherence | 90.96 | 99.94 | WP_011227179 |
| OBMDHJLN_22 | 146728 | 147321 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 90.91 | 100.00 | WP_011226149 |
| OBMDHJLN_22 | 146728 | 147321 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 90.91 | 100.00 | WP_011226149 |
| OBMDHJLN_39 | 345 | 1805 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 90.72 | 100.00 | WP_011226049 |
| OBMDHJLN_41 | 132550 | 134135 | STER_RS07050 | 0.0 | Capsule | Immune modulation | 90.31 | 93.06 | WP_041827753 |
| OBMDHJLN_41 | 132550 | 134135 | STR_RS06890 | 0.0 | Capsule | Immune modulation | 90.06 | 93.06 | WP_041827077 |
| OBMDHJLN_39 | 345 | 1805 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 89.90 | 100.00 | WP_041827043 |
| OBMDHJLN_39 | 2546 | 3238 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 89.90 | 100.00 | WP_011226047 |
| OBMDHJLN_39 | 2546 | 3238 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 89.61 | 100.00 | WP_011227247 |
| OBMDHJLN_39 | 2546 | 3238 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.47 | 100.00 | WP_011681175 |
| OBMDHJLN_1 | 8449 | 9288 | cbpD | 0.0 | Autolysin | Exoenzyme | 89.18 | 99.88 | WP_011226733 |
| OBMDHJLN_41 | 137099 | 138247 | STR_RS06910 | 0.0 | Capsule | Immune modulation | 88.77 | 100.00 | WP_011227431 |
| OBMDHJLN_41 | 130730 | 132475 | STR_RS06885 | 0.0 | Capsule | Immune modulation | 88.72 | 99.94 | WP_011227426 |
| OBMDHJLN_41 | 137099 | 138247 | STER_RS07070 | 0.0 | Capsule | Immune modulation | 88.60 | 100.00 | WP_011681439 |
| OBMDHJLN_41 | 130730 | 132475 | STER_RS07045 | 0.0 | Capsule | Immune modulation | 88.32 | 99.94 | WP_011681434 |
| OBMDHJLN_25 | 5628 | 6931 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.24 | 99.54 | WP_000022832 |
| OBMDHJLN_11 | 13537 | 14550 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 85.57 | 99.90 | WP_002986042 |
| OBMDHJLN_41 | 135355 | 136161 | SGO_RS05020 | 0.0 | Capsule | Immune modulation | 84.63 | 100.00 | WP_012000440 |
| OBMDHJLN_44 | 83788 | 84549 | srtA | 0.0 | Sortase A | Exoenzyme | 84.14 | 99.87 | - |
| OBMDHJLN_21 | 1923 | 3206 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.84 | 99.61 | WP_000107753 |
| OBMDHJLN_22 | 145412 | 146458 | rfbB | 0.0 | Capsule | Immune modulation | 80.71 | 100.00 | WP_009659423 |
| OBMDHJLN_22 | 147321 | 148190 | rfbA | 0.0 | Capsule | Immune modulation | 80.28 | 99.77 | WP_002904719 |
| OBMDHJLN_39 | 3248 | 3918 | STU_RS14635 | 2.26e-149 | Capsule | Immune modulation | 81.13 | 90.28 | WP_011226046 |
| OBMDHJLN_39 | 3248 | 3918 | STER_RS05305 | 1.05e-147 | Capsule | Immune modulation | 80.98 | 90.28 | WP_011681174 |
| OBMDHJLN_39 | 3248 | 3918 | STR_RS05250 | 1.07e-137 | Capsule | Immune modulation | 80.09 | 89.20 | WP_011227246 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| OBMDHJLN_44 | 87238 | 88221 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 96.95 | 100.00 | AAK75326 |
| OBMDHJLN_44 | 75653 | 74580 | MntE | 0.0 | manganese homeostasis | 96.09 | 99.72 | ABF32167 |
| OBMDHJLN_11 | 147676 | 145370 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 94.15 | 99.22 | AAK74619 |
| OBMDHJLN_43 | 66551 | 65070 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.92 | 100.00 | ABJ54480 |
| OBMDHJLN_14 | 11317 | 12285 | spr0084 | 0.0 | pathogenitcity related | 92.88 | 98.48 | AAK98888 |
| OBMDHJLN_44 | 56592 | 54346 | metE | 0.0 | methionine biosynthesis enzymes | 92.79 | 100.00 | AAK74738 |
| OBMDHJLN_30 | 308 | 1279 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 91.67 | 100.00 | ABF36968 |
| OBMDHJLN_22 | 174985 | 173255 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 89.95 | 100.00 | AAK34199 |
| OBMDHJLN_11 | 281122 | 282273 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.58 | 99.74 | AAL00050 |
| OBMDHJLN_1 | 76241 | 78229 | uvrB | 0.0 | excinuclease ABC, B subunit | 89.29 | 100.00 | AE014259_2 |
| OBMDHJLN_45 | 60360 | 58882 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.83 | 100.00 | ADE32434 |
| OBMDHJLN_25 | 5628 | 6929 | Eno | 0.0 | enolase | 86.44 | 99.77 | ABP90468 |
| OBMDHJLN_45 | 45010 | 43118 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| OBMDHJLN_8 | 1226 | 135 | recA | 0.0 | DNA recombination and repair | 84.64 | 95.36 | AAL00560 |
| OBMDHJLN_44 | 51428 | 53137 | PGM | 0.0 | phosphoglucomutase | 84.59 | 99.65 | ACH87041 |
| OBMDHJLN_39 | 105687 | 107048 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.89 | 99.56 | ABP90420 |
| OBMDHJLN_2 | 19349 | 20359 | pdh | 0.0 | pyruvate dehydrogenase | 82.79 | 99.70 | ABP91006 |
| OBMDHJLN_3 | 65511 | 66401 | bglB | 8.04e-178 | putative phospho--glucosidase | 87.20 | 99.66 | AAK33487 |
| OBMDHJLN_44 | 9947 | 10897 | SP_0676 | 1.41e-170 | transcription facot | 81.39 | 98.45 | AAK74821 |
| OBMDHJLN_44 | 54156 | 53299 | metF | 1.09e-168 | methionine biosynthesis enzymes | 86.71 | 99.31 | AAK74739 |
| OBMDHJLN_16 | 1834 | 2538 | covR | 8.34e-128 | responder protein | 85.53 | 100.00 | AAK71319 |
| OBMDHJLN_43 | 122892 | 123563 | rr01 | 2.82e-127 | response regulator | 84.82 | 99.56 | CAB54566 |
| OBMDHJLN_44 | 46763 | 46092 | ciaR | 9.17e-126 | two component system response regulator | 86.16 | 99.12 | AIK75708 |
| OBMDHJLN_44 | 46763 | 46095 | CiaR | 1.69e-125 | two-component response regulator | 87.44 | 99.55 | AAK74935 |
| OBMDHJLN_16 | 1834 | 2538 | walR | 1.90e-121 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| OBMDHJLN_33 | 144249 | 144935 | CovR | 4.91e-120 | serves to repress GAS virulence factor-encoding genes | 81.66 | 100.00 | ACE75886 |
| OBMDHJLN_22 | 247322 | 247717 | SpxA2 | 2.44e-75 | transcriptional regulator | 91.67 | 100.00 | ERL21461 |
| OBMDHJLN_39 | 94220 | 93819 | SpxA1 | 1.13e-69 | transcriptional regulator | 82.09 | 100.00 | ERL19273 |
| OBMDHJLN_13 | 15404 | 15817 | GrpE | 1.66e-68 | protein grpE | 81.88 | 80.59 | ABP89267 |
| OBMDHJLN_33 | 167444 | 167731 | spr0479 | 5.24e-48 | essential gene | 85.42 | 98.97 | AAK99283 |
| OBMDHJLN_9 | 24619 | 24365 | spr1327 | 1.61e-45 | essential gene | 92.94 | 100.00 | AAL00131 |
| OBMDHJLN_45 | 13829 | 14092 | spr0175 | 6.14e-43 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| OBMDHJLN_45 | 14654 | 14920 | spr0177 | 9.89e-42 | essential gene | 83.15 | 88.12 | AAK98981 |
| OBMDHJLN_21 | 3373 | 3864 | RopE (M5005_Spy_1611) | 4.59e-74 | probable DNA-directed RNA polymerase subunit delta | 82.93 | 85.86 | AAK34603 |
| OBMDHJLN_11 | 147676 | 145376 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.22 | 98.08 | MYN69560 |
| OBMDHJLN_2 | 55475 | 54456 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 85.88 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| OBMDHJLN_1 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_2 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_3 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_4 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_5 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_6 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_7 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_8 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_9 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_10 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_11 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_12 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_13 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_14 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_15 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_16 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_17 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_18 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_19 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_20 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_21 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_22 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_23 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_25 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_27 | 1.0 | 0.0 | 1.0 |
| OBMDHJLN_28 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_29 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_30 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_31 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_32 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_33 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_39 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_40 | 1.0 | 0.0 | 1.0 |
| OBMDHJLN_41 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_43 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_44 | 0.0 | 1.0 | 0.0 |
| OBMDHJLN_45 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| OBMDHJLN_22 | 16580 | 60466 | False | Siphoviridae | VOG1887, VOG4564, VOG4649, VOG0054, VOG0641, VOG0648, VOG0647, VOG4599, VOG4605, VOG4545, VOG0209, VOG4586, VOG0207, VOG0205, VOG0204, VOG4553, VOG4553, VOG4573, VOG4556, VOG0202, VOG1886, VOG4581, VOG4841, VOG0198, VOG0658, VOG0657, VOG4567, VOG9667, VOG0152, VOG6414, VOG0656, VOG0655, VOG4609, VOG4632, VOG6545, VOG0322, VOG6419, VOG6420, VOG0321, VOG5996, VOG0651, VOG0650, VOG9469, VOG1564, VOG3459, VOG6627, VOG0743, VOG6422, VOG4602 |
Phigaro v2.4.0 (Database: Jan. 2024 release)