Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 25 | 33 | 41.40 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| OKDNFOMD_1 | 3354 | 4223 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| OKDNFOMD_1 | 2761 | 3354 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| OKDNFOMD_11 | 196360 | 197169 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| OKDNFOMD_1 | 2761 | 3354 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| OKDNFOMD_4 | 13689 | 14420 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 99.73 | 100.00 | WP_011681176 |
| OKDNFOMD_1 | 2761 | 3354 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| OKDNFOMD_22 | 20819 | 21658 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.64 | 100.00 | WP_011226733 |
| OKDNFOMD_3 | 1088 | 2231 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 99.56 | 100.00 | - |
| OKDNFOMD_11 | 199446 | 201230 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.55 | 100.00 | WP_011226325 |
| OKDNFOMD_15 | 13061 | 14719 | fbp54 | 0.0 | FBPs | Adherence | 99.46 | 100.00 | WP_011227179 |
| OKDNFOMD_11 | 195420 | 196376 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.37 | 100.00 | WP_011226328 |
| OKDNFOMD_11 | 197169 | 198374 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.25 | 100.00 | WP_011226326 |
| OKDNFOMD_11 | 198394 | 199449 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.15 | 100.00 | WP_002948022 |
| OKDNFOMD_11 | 190343 | 191617 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 98.98 | 100.00 | WP_011226331 |
| OKDNFOMD_11 | 194275 | 195423 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 98.61 | 100.00 | WP_041828290 |
| OKDNFOMD_11 | 191617 | 192579 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 98.55 | 95.25 | WP_011226330 |
| OKDNFOMD_4 | 12238 | 12978 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 98.52 | 100.00 | WP_011681174 |
| OKDNFOMD_4 | 12238 | 12978 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 98.38 | 100.00 | WP_011226046 |
| OKDNFOMD_4 | 12243 | 12978 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 98.10 | 98.13 | WP_011227246 |
| OKDNFOMD_4 | 14421 | 15881 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.95 | 100.00 | WP_011681177 |
| OKDNFOMD_4 | 13689 | 14420 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 97.95 | 100.00 | WP_011227248 |
| OKDNFOMD_4 | 13689 | 14420 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.81 | 100.00 | WP_011226048 |
| OKDNFOMD_1 | 38120 | 38881 | srtA | 0.0 | Sortase A | Exoenzyme | 97.64 | 100.00 | - |
| OKDNFOMD_11 | 188389 | 189240 | rfbD | 0.0 | Capsule | Immune modulation | 97.07 | 100.00 | WP_014621820 |
| OKDNFOMD_4 | 14421 | 15881 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.65 | 100.21 | WP_011226049 |
| OKDNFOMD_4 | 14421 | 15881 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.83 | 100.21 | WP_041827043 |
| OKDNFOMD_4 | 10817 | 12182 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.39 | 99.85 | WP_011681173 |
| OKDNFOMD_4 | 10815 | 12182 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.44 | 100.00 | WP_011226045 |
| OKDNFOMD_4 | 12988 | 13680 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 92.50 | 100.00 | WP_011681175 |
| OKDNFOMD_54 | 35824 | 37127 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| OKDNFOMD_4 | 12988 | 13680 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 87.88 | 100.00 | WP_011226047 |
| OKDNFOMD_4 | 12988 | 13680 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 87.59 | 100.00 | WP_011227247 |
| OKDNFOMD_26 | 183 | 1193 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.54 | 99.41 | WP_002986042 |
| OKDNFOMD_2 | 59445 | 60728 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.65 | 99.77 | WP_000107753 |
| OKDNFOMD_1 | 1286 | 2332 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| OKDNFOMD_4 | 1284 | 1867 | SPD_RS01775 | 2.91e-148 | Capsule | Immune modulation | 83.11 | 96.04 | WP_001819836 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| OKDNFOMD_1 | 41568 | 42551 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| OKDNFOMD_9 | 26824 | 27897 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| OKDNFOMD_11 | 25805 | 23502 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| OKDNFOMD_3 | 12334 | 13302 | spr0084 | 0.0 | pathogenitcity related | 92.88 | 98.48 | AAK98888 |
| OKDNFOMD_53 | 56201 | 54720 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.71 | 100.00 | ABJ54480 |
| OKDNFOMD_24 | 11330 | 9084 | metE | 0.0 | methionine biosynthesis enzymes | 91.86 | 100.00 | AAK74738 |
| OKDNFOMD_22 | 2025 | 1027 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| OKDNFOMD_12 | 30629 | 31600 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| OKDNFOMD_11 | 175214 | 177202 | uvrB | 0.0 | excinuclease ABC, B subunit | 89.44 | 100.00 | AE014259_2 |
| OKDNFOMD_11 | 139572 | 140723 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| OKDNFOMD_1 | 25372 | 23642 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| OKDNFOMD_22 | 49834 | 51312 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| OKDNFOMD_54 | 35824 | 37125 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| OKDNFOMD_22 | 64570 | 66462 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| OKDNFOMD_24 | 6159 | 7868 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| OKDNFOMD_56 | 54851 | 53841 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| OKDNFOMD_10 | 3549 | 2188 | mnmE | 0.0 | central tRNA-modifying GTPase | 81.80 | 99.56 | ABP90420 |
| OKDNFOMD_56 | 4521 | 6413 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| OKDNFOMD_54 | 21385 | 22275 | bglB | 5.73e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| OKDNFOMD_55 | 67421 | 68359 | SP_0676 | 9.99e-169 | transcription facot | 81.15 | 97.20 | AAK74821 |
| OKDNFOMD_24 | 8892 | 8035 | metF | 1.40e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| OKDNFOMD_5 | 42982 | 43686 | covR | 5.26e-133 | responder protein | 85.53 | 100.00 | AAK71319 |
| OKDNFOMD_53 | 75170 | 75841 | rr01 | 1.39e-125 | response regulator | 83.93 | 99.56 | CAB54566 |
| OKDNFOMD_5 | 42982 | 43686 | walR | 4.94e-123 | DNA-binding response regulator | 81.70 | 100.00 | ANC99504 |
| OKDNFOMD_24 | 2205 | 1537 | CiaR | 1.86e-119 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| OKDNFOMD_44 | 83737 | 84423 | CovR | 4.95e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| OKDNFOMD_24 | 2205 | 1534 | ciaR | 1.83e-117 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| OKDNFOMD_22 | 751 | 377 | SpxA2 | 7.75e-71 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| OKDNFOMD_10 | 14970 | 15371 | SpxA1 | 6.79e-68 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| OKDNFOMD_21 | 13717 | 14004 | spr0479 | 1.35e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| OKDNFOMD_33 | 23106 | 22852 | spr1327 | 1.61e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| OKDNFOMD_22 | 109139 | 108876 | spr0175 | 4.81e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| OKDNFOMD_22 | 108312 | 108046 | spr0177 | 1.05e-33 | essential gene | 84.27 | 88.12 | AAK98981 |
| OKDNFOMD_2 | 59287 | 58787 | RopE (M5005_Spy_1611) | 1.68e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| OKDNFOMD_11 | 25805 | 23508 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| OKDNFOMD_56 | 18964 | 19983 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| OKDNFOMD_1 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_2 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_3 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_4 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_5 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_6 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_7 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_8 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_9 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_10 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_11 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_12 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_13 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_14 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_15 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_16 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_17 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_18 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_19 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_20 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_21 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_22 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_23 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_24 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_25 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_26 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_27 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_28 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_29 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_30 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_31 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_32 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_33 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_34 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_36 | 1.0 | 0.0 | 1.0 |
| OKDNFOMD_37 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_38 | 1.0 | 0.0 | 1.0 |
| OKDNFOMD_39 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_40 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_41 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_42 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_43 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_44 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_52 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_53 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_54 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_55 | 0.0 | 1.0 | 0.0 |
| OKDNFOMD_56 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)