Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 22 | 32 | 38.83 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| CNOHIGJC_43 | 19509 | 20378 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| CNOHIGJC_43 | 20378 | 20971 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| CNOHIGJC_11 | 179369 | 180628 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681445 |
| CNOHIGJC_43 | 20378 | 20971 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| CNOHIGJC_43 | 20378 | 20971 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| CNOHIGJC_11 | 180625 | 181601 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.59 | 99.90 | WP_011681444 |
| CNOHIGJC_23 | 5808 | 7466 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| CNOHIGJC_11 | 181619 | 182587 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 99.28 | 100.00 | WP_011681443 |
| CNOHIGJC_8 | 24925 | 25686 | srtA | 0.0 | Sortase A | Exoenzyme | 99.21 | 100.00 | - |
| CNOHIGJC_2 | 54895 | 55626 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 99.18 | 100.00 | WP_011226048 |
| CNOHIGJC_2 | 54895 | 55626 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 99.04 | 100.00 | WP_011227248 |
| CNOHIGJC_2 | 54895 | 55626 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.91 | 100.00 | WP_011681176 |
| CNOHIGJC_11 | 182589 | 183304 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.32 | 99.86 | WP_011681442 |
| CNOHIGJC_11 | 183650 | 184420 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 97.92 | 99.23 | WP_011681440 |
| CNOHIGJC_22 | 9324 | 10739 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 97.88 | 100.00 | WP_011681165 |
| CNOHIGJC_2 | 53434 | 54894 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.67 | 100.00 | WP_011681177 |
| CNOHIGJC_35 | 46612 | 47571 | cbpD | 0.0 | Autolysin | Exoenzyme | 97.63 | 99.90 | WP_082302295 |
| CNOHIGJC_14 | 21670 | 22468 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 97.62 | 100.88 | - |
| CNOHIGJC_11 | 178399 | 179250 | rfbD | 0.0 | Capsule | Immune modulation | 97.30 | 100.00 | WP_014621820 |
| CNOHIGJC_2 | 55635 | 56327 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 97.11 | 100.00 | WP_011226047 |
| CNOHIGJC_2 | 55635 | 56327 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 96.97 | 100.00 | WP_011227247 |
| CNOHIGJC_2 | 53434 | 54894 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.65 | 100.21 | WP_011226049 |
| CNOHIGJC_2 | 53434 | 54894 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.96 | 100.21 | WP_041827043 |
| CNOHIGJC_2 | 57152 | 58517 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.46 | 99.85 | WP_011681173 |
| CNOHIGJC_2 | 57152 | 58519 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.08 | 100.00 | WP_011226045 |
| CNOHIGJC_2 | 56337 | 57095 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 93.41 | 100.94 | WP_011681174 |
| CNOHIGJC_2 | 56337 | 57095 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 93.02 | 100.94 | WP_011226046 |
| CNOHIGJC_2 | 56337 | 57090 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 92.71 | 99.07 | WP_011227246 |
| CNOHIGJC_2 | 55635 | 56327 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 90.06 | 99.86 | WP_011681175 |
| CNOHIGJC_24 | 95796 | 97099 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| CNOHIGJC_21 | 129 | 1139 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.54 | 99.41 | WP_002986042 |
| CNOHIGJC_43 | 21400 | 22446 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| CNOHIGJC_41 | 6304 | 7587 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.58 | 99.77 | WP_000107753 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| CNOHIGJC_8 | 22238 | 21255 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| CNOHIGJC_6 | 27983 | 29056 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| CNOHIGJC_11 | 15666 | 13363 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| CNOHIGJC_24 | 12194 | 13162 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| CNOHIGJC_38 | 80217 | 78736 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| CNOHIGJC_10 | 11433 | 9187 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| CNOHIGJC_18 | 1352 | 360 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| CNOHIGJC_9 | 29749 | 28778 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| CNOHIGJC_11 | 129466 | 130617 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| CNOHIGJC_11 | 165361 | 167349 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| CNOHIGJC_8 | 38436 | 40166 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.87 | 100.00 | AAK34199 |
| CNOHIGJC_39 | 27413 | 28891 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| CNOHIGJC_24 | 95796 | 97097 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| CNOHIGJC_39 | 42602 | 44494 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| CNOHIGJC_10 | 6262 | 7971 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| CNOHIGJC_13 | 21439 | 22449 | pdh | 0.0 | pyruvate dehydrogenase | 82.79 | 99.70 | ABP91006 |
| CNOHIGJC_1 | 62668 | 64029 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| CNOHIGJC_3 | 5545 | 7437 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| CNOHIGJC_24 | 81361 | 82251 | bglB | 4.84e-179 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| CNOHIGJC_4 | 10170 | 9235 | SP_0676 | 3.58e-169 | transcription facot | 81.73 | 96.89 | AAK74821 |
| CNOHIGJC_10 | 8995 | 8138 | metF | 2.30e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| CNOHIGJC_2 | 16614 | 17318 | covR | 1.49e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| CNOHIGJC_38 | 99192 | 99863 | rr01 | 2.04e-125 | response regulator | 83.93 | 99.56 | CAB54566 |
| CNOHIGJC_2 | 16614 | 17318 | walR | 6.26e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| CNOHIGJC_10 | 2308 | 1640 | CiaR | 3.05e-119 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| CNOHIGJC_42 | 7906 | 7220 | CovR | 4.49e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| CNOHIGJC_10 | 2308 | 1637 | ciaR | 3.00e-117 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| CNOHIGJC_1 | 51304 | 50903 | SpxA1 | 1.32e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| CNOHIGJC_7 | 25699 | 25412 | spr0479 | 3.12e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| CNOHIGJC_35 | 5724 | 5470 | spr1327 | 1.44e-44 | essential gene | 94.12 | 100.00 | AAL00131 |
| CNOHIGJC_39 | 76231 | 75968 | spr0175 | 4.15e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| CNOHIGJC_39 | 75404 | 75138 | spr0177 | 9.07e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| CNOHIGJC_41 | 7745 | 8245 | RopE (M5005_Spy_1611) | 2.27e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| CNOHIGJC_11 | 15666 | 13369 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| CNOHIGJC_3 | 20019 | 21038 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| CNOHIGJC_1 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_2 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_3 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_4 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_5 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_6 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_7 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_8 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_9 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_10 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_11 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_12 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_13 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_14 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_15 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_16 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_18 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_19 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_20 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_21 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_22 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_23 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_24 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_25 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_26 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_27 | 1.0 | 0.0 | 1.0 |
| CNOHIGJC_28 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_29 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_30 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_31 | 1.0 | 0.0 | 1.0 |
| CNOHIGJC_32 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_33 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_34 | 1.0 | 0.0 | 1.0 |
| CNOHIGJC_35 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_38 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_39 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_40 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_41 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_42 | 0.0 | 1.0 | 0.0 |
| CNOHIGJC_43 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)