Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 8 | 10 | 4 | 13.42 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| MODAAGPP_1 | 3525172 | 3525489 | ykkD | ARO:3003064 | ykkD | 98.10 | 100.00 | AL009126.1 |
| MODAAGPP_1 | 3524834 | 3525172 | ykkC | ARO:3003063 | ykkC | 98.21 | 100.00 | AL009126.1 |
| MODAAGPP_1 | 2996355 | 2998925 | Bacillus subtilis mprF | ARO:3003324 | Bsub_mprF | 99.77 | 100.00 | AL009126.3 |
| MODAAGPP_1 | 2677480 | 2679126 | vmlR | ARO:3004476 | vmlR | 98.18 | 100.18 | NC_000964.3 |
| MODAAGPP_1 | 2375952 | 2377385 | lmrB | ARO:3002813 | lmrB | 98.95 | 100.00 | JYFL01000006.1 |
| MODAAGPP_1 | 452246 | 453448 | blt | ARO:3003006 | blt | 98.00 | 100.00 | L32599.1 |
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| MODAAGPP_1 | 2357419 | 2358338 | mph(K) | Spiramycin, Telithromycin | 97.61 | 99.89 | NC_000964 |
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| MODAAGPP_1 | 2677483 | 2679126 | vmlR | ABC-F type ribosomal protection protein VmlR | BLASTX | 98.18 | 100.00 | WP_003234144.1 |
| MODAAGPP_1 | 2047947 | 2048465 | satA | streptothricin N-acetyltransferase SatA | BLASTX | 91.91 | 100.00 | WP_003242546.1 |
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| MODAAGPP_1 | 1560057 | 1561238 | capB | 0.0 | Capsule | Immune modulation | 99.49 | 100.00 | NP_391471 |
| MODAAGPP_1 | 1077232 | 1078017 | dhbA | 0.0 | Bacillibactin | Nutritional/Metabolic factor | 99.36 | 100.00 | NP_391080 |
| MODAAGPP_1 | 1558432 | 1559574 | capA | 0.0 | Capsule | Immune modulation | 99.21 | 100.00 | NP_391469 |
| MODAAGPP_1 | 1073407 | 1074345 | dhbB | 0.0 | Bacillibactin | Nutritional/Metabolic factor | 98.94 | 100.00 | NP_391077 |
| MODAAGPP_1 | 4143978 | 4145738 | dep/capD | 0.0 | Capsule | Immune modulation | 98.92 | 99.94 | NP_389723 |
| MODAAGPP_1 | 1559593 | 1560042 | capC | 0.0 | Capsule | Immune modulation | 98.89 | 100.00 | NP_391470 |
| MODAAGPP_1 | 1076010 | 1077206 | dhbC | 0.0 | Bacillibactin | Nutritional/Metabolic factor | 98.58 | 100.00 | NP_391079 |
| MODAAGPP_1 | 1066251 | 1073387 | dhbF | 0.0 | Bacillibactin | Nutritional/Metabolic factor | 97.97 | 100.00 | NP_391076 |
| MODAAGPP_1 | 36227 | 36868 | hlyIII | 0.0 | Hemolysin III | Exotoxin | 97.82 | 100.00 | NP_390062 |
| MODAAGPP_1 | 1074373 | 1075992 | dhbE | 0.0 | Bacillibactin | Nutritional/Metabolic factor | 97.28 | 100.00 | NP_391078 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| MODAAGPP_1 | 2209918 | 2211054 | tufA | 0.0 | elongation factor Tu | 85.75 | 95.69 | AHM69299 |
| MODAAGPP_1 | 2096124 | 2096993 | pdxS | 5.59e-149 | encodes the putative pyridoxal 5'-phosphate synthase subunit PdxS | 83.45 | 98.31 | ACE61268 |
| MODAAGPP_1 | 3843786 | 3844562 | CodY | 3.48e-124 | nutrient-responsive regulator | 81.08 | 100.00 | ACJ80679 |
| MODAAGPP_1 | 1397391 | 1397960 | ClpP | 2.58e-98 | part of proteolytic complex | 81.05 | 97.44 | BAB94595 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| MODAAGPP_1 | 0.0 | 1.0 | 0.0 |
| MODAAGPP_2 | 1.0 | 0.0 | 1.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| MODAAGPP_1 | 9577 | 13175 | False | Siphoviridae | VOG3390, VOG4574, VOG8537, VOG0054 |
| MODAAGPP_1 | 69488 | 87274 | False | Siphoviridae | VOG4705, VOG0804, VOG4856, VOG4619, VOG3462, VOG0801, VOG6163, VOG5852, VOG4586, VOG0704, VOG4589, VOG0204, VOG4553, VOG4573 |
| MODAAGPP_1 | 584411 | 621832 | False | Siphoviridae | VOG4574, VOG0641, VOG4705, VOG6243, VOG4612, VOG4626, VOG4619, VOG0801, VOG6163, VOG5910, VOG0541, VOG4586, VOG0704, VOG0539, VOG4589, VOG0204, VOG5361, VOG4553, VOG4573, VOG4556, VOG0202, VOG1886, VOG4581, VOG4841, VOG0713, VOG7884, VOG0198, VOG4548, VOG0327, VOG4609, VOG0026, VOG1565, VOG1565, VOG0021, VOG1047, VOG7438 |
| MODAAGPP_1 | 1158767 | 1186283 | False | Siphoviridae | VOG3490, VOG4615, VOG0641, VOG4705, VOG6243, VOG4612, VOG4626, VOG4619, VOG0801, VOG6163, VOG5910, VOG0541, VOG4586, VOG0704, VOG0539, VOG4589, VOG0204, VOG5361, VOG4553, VOG4568, VOG4556, VOG3644, VOG4544, VOG4581, VOG4556, VOG4841, VOG0531, VOG0275, VOG0198 |
| MODAAGPP_1 | 3374861 | 3377950 | False | Unknown | VOG9667, VOG9667, VOG8241, VOG4552 |
| MODAAGPP_1 | 3386737 | 3414863 | False | Siphoviridae | VOG0198, VOG0796, VOG10227, VOG0720, VOG4564, VOG6778, VOG4555, VOG4553, VOG1125, VOG0815, VOG4623, VOG0816, VOG5660, VOG0724, VOG0799, VOG2621, VOG0725, VOG4545, VOG4605, VOG4599, VOG6965, VOG4599, VOG5535, VOG10940, VOG0753, VOG0136, VOG4574 |
| MODAAGPP_1 | 3467562 | 3493578 | False | Myoviridae | VOG4602, VOG9667, VOG3490, VOG0189, VOG4861, VOG5447, VOG0796, VOG10227, VOG4773, VOG4685, VOG0749, VOG3890, VOG3891, VOG3892, VOG6163, VOG4865, VOG4885, VOG3894, VOG4550, VOG4691, VOG4862, VOG5384, VOG4705 |
| MODAAGPP_1 | 3968975 | 3983358 | False | Unknown | VOG10230, VOG4358, VOG9712, VOG5042, VOG3389, VOG4910 |
| MODAAGPP_1 | 4246931 | 4276638 | False | Siphoviridae | VOG0136, VOG5221, VOG4705, VOG0804, VOG4856, VOG4619, VOG3462, VOG0801, VOG6163, VOG0660, VOG5852, VOG4586, VOG0207, VOG4589, VOG0204, VOG4553, VOG4573, VOG4556, VOG4544, VOG4581, VOG4841, VOG1638, VOG2545, VOG0376, VOG5447, VOG0901, VOG1884, VOG0025, VOG9600, VOG11060, VOG3547 |
Phigaro v2.4.0 (Database: Jan. 2024 release)