Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 16 | 37 | 40.31 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| KBHOMAJI_15 | 43267 | 43998 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 94.81 | 100.00 | WP_011681176 |
| KBHOMAJI_15 | 43267 | 43998 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 94.54 | 100.00 | WP_011226048 |
| KBHOMAJI_3 | 30665 | 31516 | rfbD | 0.0 | Capsule | Immune modulation | 94.48 | 100.00 | WP_014621820 |
| KBHOMAJI_3 | 34241 | 34957 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 94.42 | 100.00 | WP_011681442 |
| KBHOMAJI_15 | 43267 | 43998 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 94.13 | 100.00 | WP_011227248 |
| KBHOMAJI_3 | 35303 | 36073 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 92.35 | 99.23 | WP_011681440 |
| KBHOMAJI_7 | 60006 | 60599 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 91.08 | 100.00 | WP_011226149 |
| KBHOMAJI_2 | 129229 | 130887 | fbp54 | 0.0 | FBPs | Adherence | 90.96 | 99.94 | WP_011227179 |
| KBHOMAJI_15 | 41806 | 43266 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 90.92 | 99.86 | WP_011681177 |
| KBHOMAJI_7 | 60006 | 60599 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 90.91 | 100.00 | WP_011226149 |
| KBHOMAJI_7 | 60006 | 60599 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 90.91 | 100.00 | WP_011226149 |
| KBHOMAJI_15 | 41806 | 43266 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 90.78 | 100.00 | WP_011226049 |
| KBHOMAJI_15 | 41806 | 43266 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 89.97 | 100.00 | WP_041827043 |
| KBHOMAJI_26 | 8884 | 9789 | cbpD | 0.0 | Autolysin | Exoenzyme | 89.96 | 93.50 | WP_082302295 |
| KBHOMAJI_15 | 44007 | 44699 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 89.90 | 100.00 | WP_011226047 |
| KBHOMAJI_15 | 44007 | 44699 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 89.61 | 100.00 | WP_011227247 |
| KBHOMAJI_15 | 44007 | 44699 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.47 | 100.00 | WP_011681175 |
| KBHOMAJI_6 | 38255 | 39558 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.17 | 99.54 | WP_000022832 |
| KBHOMAJI_5 | 14451 | 15464 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 85.67 | 99.90 | WP_002986042 |
| KBHOMAJI_19 | 39737 | 40498 | srtA | 0.0 | Sortase A | Exoenzyme | 83.88 | 99.87 | - |
| KBHOMAJI_7 | 60869 | 61915 | rfbB | 0.0 | Capsule | Immune modulation | 83.49 | 99.90 | WP_002263087 |
| KBHOMAJI_8 | 1971 | 3254 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.84 | 99.61 | WP_000107753 |
| KBHOMAJI_7 | 59137 | 60006 | rfbA | 0.0 | Capsule | Immune modulation | 80.28 | 99.77 | WP_002904719 |
| KBHOMAJI_15 | 44709 | 45379 | STU_RS14635 | 3.00e-148 | Capsule | Immune modulation | 80.98 | 90.28 | WP_011226046 |
| KBHOMAJI_15 | 44709 | 45379 | STER_RS05305 | 1.40e-146 | Capsule | Immune modulation | 80.83 | 90.28 | WP_011681174 |
| KBHOMAJI_15 | 44709 | 45311 | STR_RS05250 | 1.42e-136 | Capsule | Immune modulation | 81.46 | 80.13 | WP_011227246 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| KBHOMAJI_19 | 37047 | 36064 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 96.95 | 100.00 | AAK75326 |
| KBHOMAJI_28 | 22849 | 21776 | MntE | 0.0 | manganese homeostasis | 96.09 | 99.72 | ABF32167 |
| KBHOMAJI_10 | 28721 | 26415 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 94.28 | 99.22 | AAK74619 |
| KBHOMAJI_36 | 11093 | 10125 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| KBHOMAJI_1 | 83875 | 85356 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 93.12 | 100.00 | ABJ54480 |
| KBHOMAJI_28 | 3791 | 1545 | metE | 0.0 | methionine biosynthesis enzymes | 93.06 | 100.00 | AAK74738 |
| KBHOMAJI_29 | 23294 | 22323 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 91.67 | 100.00 | ABF36968 |
| KBHOMAJI_32 | 6136 | 12609 | PrtA | 0.0 | serine protease | 91.21 | 100.61 | ABJ55268 |
| KBHOMAJI_7 | 34309 | 36039 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 89.95 | 100.00 | AAK34199 |
| KBHOMAJI_11 | 66948 | 68099 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| KBHOMAJI_3 | 16963 | 18951 | uvrB | 0.0 | excinuclease ABC, B subunit | 89.29 | 100.00 | AE014259_2 |
| KBHOMAJI_23 | 25924 | 27402 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.83 | 100.00 | ADE32434 |
| KBHOMAJI_6 | 38255 | 39556 | Eno | 0.0 | enolase | 86.44 | 99.77 | ABP90468 |
| KBHOMAJI_22 | 34544 | 32652 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| KBHOMAJI_39 | 2080 | 989 | recA | 0.0 | DNA recombination and repair | 84.91 | 95.36 | AAL00560 |
| KBHOMAJI_2 | 2165 | 456 | PGM | 0.0 | phosphoglucomutase | 84.59 | 99.65 | ACH87041 |
| KBHOMAJI_4 | 30824 | 31834 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| KBHOMAJI_14 | 50415 | 51776 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.89 | 99.56 | ABP90420 |
| KBHOMAJI_6 | 23841 | 24731 | bglB | 4.83e-177 | putative phospho--glucosidase | 86.87 | 99.66 | AAK33487 |
| KBHOMAJI_2 | 43719 | 42769 | SP_0676 | 2.10e-170 | transcription facot | 81.39 | 98.45 | AAK74821 |
| KBHOMAJI_28 | 1355 | 498 | metF | 1.20e-169 | methionine biosynthesis enzymes | 87.06 | 99.31 | AAK74739 |
| KBHOMAJI_3 | 30665 | 31486 | GacA | 4.04e-148 | dTDP-4-dehydrorhamnose reductas | 80.66 | 96.48 | AAZ51220 |
| KBHOMAJI_56 | 2601 | 1921 | NisR | 2.01e-134 | two-component signal-transduction systems | 94.27 | 100.00 | ABP89873 |
| KBHOMAJI_56 | 1933 | 1229 | NisK | 3.26e-134 | two-component signal-transduction systems | 91.06 | 100.00 | ABP89872 |
| KBHOMAJI_15 | 9491 | 10195 | covR | 2.24e-127 | responder protein | 85.53 | 100.00 | AAK71319 |
| KBHOMAJI_1 | 17783 | 17112 | rr01 | 3.69e-127 | response regulator | 84.82 | 99.56 | CAB54566 |
| KBHOMAJI_2 | 6831 | 7502 | ciaR | 1.36e-125 | two component system response regulator | 86.16 | 99.12 | AIK75708 |
| KBHOMAJI_2 | 6831 | 7499 | CiaR | 2.52e-125 | two-component response regulator | 87.44 | 99.55 | AAK74935 |
| KBHOMAJI_15 | 9491 | 10195 | walR | 5.10e-121 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| KBHOMAJI_9 | 53992 | 53306 | CovR | 6.82e-121 | serves to repress GAS virulence factor-encoding genes | 82.10 | 100.00 | ACE75886 |
| KBHOMAJI_39 | 815 | 420 | SpxA2 | 1.45e-76 | transcriptional regulator | 91.67 | 100.00 | ERL21461 |
| KBHOMAJI_14 | 38957 | 38556 | SpxA1 | 3.37e-70 | transcriptional regulator | 82.09 | 100.00 | ERL19273 |
| KBHOMAJI_38 | 7225 | 6812 | GrpE | 1.22e-68 | protein grpE | 81.88 | 80.59 | ABP89267 |
| KBHOMAJI_9 | 30789 | 30502 | spr0479 | 4.47e-48 | essential gene | 85.42 | 98.97 | AAK99283 |
| KBHOMAJI_20 | 16792 | 17046 | spr1327 | 1.36e-46 | essential gene | 94.12 | 100.00 | AAL00131 |
| KBHOMAJI_33 | 7705 | 7968 | spr0175 | 1.19e-43 | pathogenitcity related | 85.23 | 100.00 | AAK98979 |
| KBHOMAJI_33 | 8530 | 8796 | spr0177 | 2.63e-42 | essential gene | 83.15 | 88.12 | AAK98981 |
| KBHOMAJI_8 | 3421 | 3912 | RopE (M5005_Spy_1611) | 4.28e-73 | probable DNA-directed RNA polymerase subunit delta | 83.54 | 85.86 | AAK34603 |
| KBHOMAJI_10 | 28721 | 26421 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.97 | 98.08 | MYN69560 |
| KBHOMAJI_4 | 79320 | 78301 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 85.88 | 100.00 | ABJ55451 |
| KBHOMAJI_2 | 105914 | 106453 | pnuC | 8.29e-95 | NAD salvage pathway importer | 84.44 | 66.91 | AAK75931 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| KBHOMAJI_1 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_2 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_3 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_4 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_5 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_6 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_7 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_8 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_9 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_10 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_11 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_12 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_13 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_14 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_15 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_16 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_17 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_18 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_19 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_20 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_21 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_22 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_23 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_24 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_25 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_26 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_27 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_28 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_29 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_30 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_31 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_32 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_33 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_34 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_35 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_36 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_37 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_38 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_39 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_40 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_41 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_42 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_43 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_44 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_45 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_46 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_47 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_48 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_49 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_50 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_51 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_52 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_53 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_54 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_55 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_56 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_58 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_59 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_60 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_61 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_62 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_63 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_64 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_65 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_67 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_68 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_69 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_70 | 1.0 | 0.0 | 1.0 |
| KBHOMAJI_71 | 0.0 | 1.0 | 0.0 |
| KBHOMAJI_72 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)