Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 27 | 33 | 42.64 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| OGEHJABF_23 | 20253 | 20846 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| OGEHJABF_1 | 183120 | 183836 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681442 |
| OGEHJABF_1 | 182151 | 183119 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681443 |
| OGEHJABF_1 | 189189 | 190889 | STER_RS07050 | 0.0 | Capsule | Immune modulation | 99.94 | 100.00 | WP_041827753 |
| OGEHJABF_1 | 179901 | 181160 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 99.92 | 100.00 | WP_011681445 |
| OGEHJABF_1 | 185077 | 186225 | STER_RS07070 | 0.0 | Capsule | Immune modulation | 99.91 | 100.00 | WP_011681439 |
| OGEHJABF_23 | 19384 | 20253 | rfbA | 0.0 | Capsule | Immune modulation | 99.89 | 100.00 | WP_011681286 |
| OGEHJABF_1 | 186222 | 187163 | STER_RS07065 | 0.0 | Capsule | Immune modulation | 99.89 | 100.00 | WP_011681438 |
| OGEHJABF_1 | 184182 | 184958 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 99.87 | 100.00 | WP_011681440 |
| OGEHJABF_1 | 190891 | 192636 | STER_RS07045 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011681434 |
| OGEHJABF_1 | 187969 | 189171 | STER_RS07055 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011681436 |
| OGEHJABF_23 | 20253 | 20846 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| OGEHJABF_1 | 189189 | 190889 | STR_RS06890 | 0.0 | Capsule | Immune modulation | 99.77 | 100.00 | WP_041827077 |
| OGEHJABF_49 | 92952 | 94610 | fbp54 | 0.0 | FBPs | Adherence | 99.70 | 100.00 | WP_011227179 |
| OGEHJABF_23 | 20253 | 20846 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| OGEHJABF_12 | 217388 | 218531 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 99.65 | 100.00 | - |
| OGEHJABF_1 | 187163 | 187969 | STER_RS07060 | 0.0 | Capsule | Immune modulation | 99.63 | 100.00 | WP_011681437 |
| OGEHJABF_1 | 181157 | 182133 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.59 | 99.90 | WP_011681444 |
| OGEHJABF_1 | 187969 | 189171 | STR_RS06895 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011227428 |
| OGEHJABF_1 | 186222 | 187163 | STR_RS06905 | 0.0 | Capsule | Immune modulation | 99.36 | 100.00 | WP_011227430 |
| OGEHJABF_1 | 185077 | 186225 | STR_RS06910 | 0.0 | Capsule | Immune modulation | 99.30 | 100.00 | WP_011227431 |
| OGEHJABF_1 | 187163 | 187969 | STR_RS06900 | 0.0 | Capsule | Immune modulation | 99.13 | 100.00 | WP_011227429 |
| OGEHJABF_23 | 143168 | 143908 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 98.78 | 100.00 | WP_011681174 |
| OGEHJABF_23 | 143168 | 143903 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 98.23 | 98.13 | WP_011227246 |
| OGEHJABF_1 | 190891 | 192636 | STR_RS06885 | 0.0 | Capsule | Immune modulation | 98.17 | 100.00 | WP_011227426 |
| OGEHJABF_23 | 143168 | 143908 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 98.11 | 100.00 | WP_011226046 |
| OGEHJABF_23 | 142466 | 143158 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 97.69 | 100.00 | WP_011226047 |
| OGEHJABF_23 | 140265 | 141725 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.67 | 100.00 | WP_011681177 |
| OGEHJABF_50 | 88368 | 89129 | srtA | 0.0 | Sortase A | Exoenzyme | 97.64 | 100.00 | - |
| OGEHJABF_34 | 63306 | 64265 | cbpD | 0.0 | Autolysin | Exoenzyme | 97.63 | 99.79 | WP_082302295 |
| OGEHJABF_23 | 141726 | 142457 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.54 | 100.00 | WP_011226048 |
| OGEHJABF_1 | 178931 | 179782 | rfbD | 0.0 | Capsule | Immune modulation | 97.42 | 100.00 | WP_014621820 |
| OGEHJABF_23 | 142466 | 143158 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 97.40 | 100.00 | WP_011227247 |
| OGEHJABF_23 | 141726 | 142457 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 97.40 | 100.00 | WP_011227248 |
| OGEHJABF_23 | 141726 | 142457 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 97.27 | 100.00 | WP_011681176 |
| OGEHJABF_23 | 140265 | 141725 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.51 | 100.21 | WP_011226049 |
| OGEHJABF_23 | 140265 | 141725 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.69 | 100.21 | WP_041827043 |
| OGEHJABF_23 | 143966 | 145331 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.24 | 99.85 | WP_011681173 |
| OGEHJABF_23 | 143966 | 145333 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.96 | 100.00 | WP_011226045 |
| OGEHJABF_23 | 142466 | 143158 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 91.05 | 100.00 | WP_011681175 |
| OGEHJABF_12 | 114327 | 115630 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| OGEHJABF_14 | 14204 | 15214 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.54 | 99.41 | WP_002986042 |
| OGEHJABF_1 | 187163 | 187969 | SGO_RS05020 | 0.0 | Capsule | Immune modulation | 83.27 | 100.00 | WP_012000440 |
| OGEHJABF_3 | 59352 | 60635 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.65 | 99.77 | WP_000107753 |
| OGEHJABF_23 | 21275 | 22321 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| OGEHJABF_1 | 187969 | 188706 | SGO_RS05025 | 0.0 | Capsule | Immune modulation | 84.96 | 60.29 | WP_012000441 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| OGEHJABF_50 | 85681 | 84698 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.51 | 100.00 | AAK75326 |
| OGEHJABF_12 | 13923 | 12850 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| OGEHJABF_1 | 15471 | 13168 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| OGEHJABF_12 | 199274 | 198306 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| OGEHJABF_50 | 12431 | 10950 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| OGEHJABF_13 | 5487 | 7733 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| OGEHJABF_4 | 39385 | 40383 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| OGEHJABF_4 | 3272 | 4243 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| OGEHJABF_1 | 129477 | 130628 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.06 | 99.74 | AAL00050 |
| OGEHJABF_1 | 165890 | 167878 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| OGEHJABF_50 | 101879 | 103609 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| OGEHJABF_45 | 26924 | 28402 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| OGEHJABF_12 | 115630 | 114329 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| OGEHJABF_45 | 42113 | 44005 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| OGEHJABF_13 | 10658 | 8949 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| OGEHJABF_2 | 18740 | 19750 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| OGEHJABF_49 | 66473 | 67834 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| OGEHJABF_2 | 69073 | 67181 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| OGEHJABF_12 | 130066 | 129176 | bglB | 1.57e-179 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| OGEHJABF_8 | 10349 | 11287 | SP_0676 | 2.72e-169 | transcription facot | 81.15 | 97.20 | AAK74821 |
| OGEHJABF_13 | 7925 | 8782 | metF | 1.33e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| OGEHJABF_23 | 103429 | 104133 | covR | 3.70e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| OGEHJABF_50 | 31403 | 32074 | rr01 | 1.64e-126 | response regulator | 84.38 | 99.56 | CAB54566 |
| OGEHJABF_23 | 103429 | 104133 | walR | 1.56e-122 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| OGEHJABF_13 | 14612 | 15280 | CiaR | 1.78e-119 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| OGEHJABF_52 | 8114 | 7428 | CovR | 4.99e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| OGEHJABF_13 | 14612 | 15283 | ciaR | 1.75e-117 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| OGEHJABF_4 | 40659 | 41033 | SpxA2 | 2.56e-71 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| OGEHJABF_49 | 55110 | 54709 | SpxA1 | 2.18e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| OGEHJABF_5 | 25538 | 25251 | spr0479 | 3.00e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| OGEHJABF_34 | 22390 | 22136 | spr1327 | 1.48e-44 | essential gene | 94.12 | 100.00 | AAL00131 |
| OGEHJABF_45 | 80236 | 79973 | spr0175 | 4.30e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| OGEHJABF_45 | 79409 | 79143 | spr0177 | 9.40e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| OGEHJABF_3 | 59194 | 58694 | RopE (M5005_Spy_1611) | 1.75e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| OGEHJABF_1 | 15471 | 13174 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| OGEHJABF_2 | 54604 | 53585 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| OGEHJABF_1 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_2 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_3 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_4 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_5 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_6 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_7 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_8 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_9 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_10 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_11 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_12 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_13 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_14 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_15 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_17 | 1.0 | 0.0 | 1.0 |
| OGEHJABF_18 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_19 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_20 | 1.0 | 0.0 | 1.0 |
| OGEHJABF_21 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_22 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_23 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_24 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_25 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_26 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_34 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_45 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_49 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_50 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_51 | 0.0 | 1.0 | 0.0 |
| OGEHJABF_52 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)