Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 19 | 28 | 33.84 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| AMJBMGPI_1 | 1079477 | 1080070 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| AMJBMGPI_1 | 1080070 | 1080939 | rfbA | 0.0 | Capsule | Immune modulation | 99.89 | 100.00 | WP_011681286 |
| AMJBMGPI_1 | 1079477 | 1080070 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| AMJBMGPI_1 | 1079477 | 1080070 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| AMJBMGPI_1 | 851949 | 853607 | fbp54 | 0.0 | FBPs | Adherence | 99.64 | 100.00 | WP_011227179 |
| AMJBMGPI_1 | 45045 | 45884 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| AMJBMGPI_1 | 957712 | 958443 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 99.04 | 100.00 | WP_011681176 |
| AMJBMGPI_1 | 957712 | 958443 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011226048 |
| AMJBMGPI_1 | 957712 | 958443 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011227248 |
| AMJBMGPI_1 | 1308916 | 1309632 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.19 | 100.00 | WP_011681442 |
| AMJBMGPI_1 | 947705 | 949120 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 97.88 | 100.00 | WP_011681165 |
| AMJBMGPI_1 | 1114841 | 1115602 | srtA | 0.0 | Sortase A | Exoenzyme | 97.64 | 100.00 | - |
| AMJBMGPI_1 | 958444 | 959904 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.60 | 100.00 | WP_011681177 |
| AMJBMGPI_1 | 1313775 | 1314626 | rfbD | 0.0 | Capsule | Immune modulation | 97.53 | 100.00 | WP_014621820 |
| AMJBMGPI_1 | 956261 | 957001 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.44 | 99.87 | WP_011681174 |
| AMJBMGPI_1 | 956261 | 957001 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.03 | 99.87 | WP_011226046 |
| AMJBMGPI_1 | 957011 | 957703 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 96.97 | 100.00 | WP_011227247 |
| AMJBMGPI_1 | 957011 | 957703 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 96.97 | 99.86 | WP_011226047 |
| AMJBMGPI_1 | 956266 | 957001 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.74 | 98.00 | WP_011227246 |
| AMJBMGPI_1 | 958444 | 959904 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.30 | 100.21 | WP_011226049 |
| AMJBMGPI_1 | 958444 | 959904 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.48 | 100.21 | WP_041827043 |
| AMJBMGPI_1 | 954839 | 956204 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.46 | 99.85 | WP_011681173 |
| AMJBMGPI_1 | 1307800 | 1308570 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 94.43 | 99.10 | WP_011681440 |
| AMJBMGPI_1 | 954837 | 956204 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.08 | 100.00 | WP_011226045 |
| AMJBMGPI_1 | 1024575 | 1025350 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 92.94 | 99.12 | - |
| AMJBMGPI_1 | 957011 | 957703 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 90.04 | 100.00 | WP_011681175 |
| AMJBMGPI_1 | 591233 | 592536 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| AMJBMGPI_1 | 1620166 | 1621176 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.46 | 99.80 | WP_002986042 |
| AMJBMGPI_1 | 144801 | 146084 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| AMJBMGPI_1 | 1078002 | 1079048 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| AMJBMGPI_1 | 1118289 | 1119272 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| AMJBMGPI_1 | 698205 | 699278 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| AMJBMGPI_1 | 1497275 | 1499026 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 94.35 | 75.45 | AAK74619 |
| AMJBMGPI_1 | 509006 | 509974 | spr0084 | 0.0 | pathogenitcity related | 92.88 | 98.48 | AAK98888 |
| AMJBMGPI_1 | 1195027 | 1196508 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.51 | 100.00 | ABJ54480 |
| AMJBMGPI_1 | 721941 | 724187 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| AMJBMGPI_1 | 64676 | 65674 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| AMJBMGPI_1 | 28562 | 29533 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| AMJBMGPI_1 | 1363491 | 1362340 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| AMJBMGPI_1 | 1327665 | 1325677 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| AMJBMGPI_1 | 1102089 | 1100359 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.22 | 100.00 | AAK34199 |
| AMJBMGPI_1 | 1819997 | 1818519 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| AMJBMGPI_1 | 591233 | 592534 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| AMJBMGPI_1 | 1805258 | 1803366 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.74 | 98.90 | ABP91129 |
| AMJBMGPI_1 | 727110 | 725401 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| AMJBMGPI_1 | 1663582 | 1664592 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| AMJBMGPI_1 | 876193 | 874832 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| AMJBMGPI_1 | 1715584 | 1713692 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| AMJBMGPI_1 | 576794 | 577684 | bglB | 5.19e-178 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| AMJBMGPI_1 | 798190 | 797252 | SP_0676 | 2.33e-167 | transcription facot | 81.15 | 97.20 | AAK74821 |
| AMJBMGPI_1 | 724378 | 725235 | metF | 8.54e-165 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| AMJBMGPI_1 | 996734 | 996030 | covR | 2.09e-131 | responder protein | 85.53 | 100.00 | AAK71319 |
| AMJBMGPI_1 | 1170415 | 1169744 | rr01 | 2.97e-124 | response regulator | 83.93 | 99.56 | CAB54566 |
| AMJBMGPI_1 | 731065 | 731733 | CiaR | 8.62e-123 | two-component response regulator | 86.10 | 99.55 | AAK74935 |
| AMJBMGPI_1 | 996734 | 996030 | walR | 1.97e-121 | DNA-binding response regulator | 81.70 | 100.00 | ANC99504 |
| AMJBMGPI_1 | 731065 | 731736 | ciaR | 1.17e-120 | two component system response regulator | 83.93 | 99.12 | AIK75708 |
| AMJBMGPI_1 | 299210 | 299896 | CovR | 9.94e-118 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| AMJBMGPI_1 | 65950 | 66324 | SpxA2 | 1.14e-69 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| AMJBMGPI_1 | 1497275 | 1499020 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 84.39 | 74.52 | MYN69560 |
| AMJBMGPI_1 | 146242 | 146742 | RopE (M5005_Spy_1611) | 4.86e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| AMJBMGPI_1 | 1701126 | 1700107 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| AMJBMGPI_1 | 0.0 | 1.0 | 0.0 |
| AMJBMGPI_2 | 1.0 | 0.0 | 1.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)