Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 25 | 29 | 38.29 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| JFONHFPA_1 | 1131164 | 1131757 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| JFONHFPA_1 | 1004847 | 1006307 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 99.93 | 100.00 | WP_011681177 |
| JFONHFPA_1 | 1131164 | 1131757 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| JFONHFPA_1 | 1345126 | 1345935 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.75 | 100.00 | WP_002948020 |
| JFONHFPA_1 | 1131757 | 1132626 | rfbA | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011681286 |
| JFONHFPA_1 | 1131164 | 1131757 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| JFONHFPA_1 | 886205 | 887863 | fbp54 | 0.0 | FBPs | Adherence | 99.64 | 100.00 | WP_011227179 |
| JFONHFPA_1 | 1345919 | 1346875 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226328 |
| JFONHFPA_1 | 43570 | 44409 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| JFONHFPA_1 | 1341053 | 1342837 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.44 | 100.00 | WP_011226325 |
| JFONHFPA_1 | 1343921 | 1345126 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.17 | 100.00 | WP_011226326 |
| JFONHFPA_1 | 1353062 | 1353913 | rfbD | 0.0 | Capsule | Immune modulation | 99.06 | 100.00 | WP_014621820 |
| JFONHFPA_1 | 1004115 | 1004846 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.91 | 100.00 | WP_011681176 |
| JFONHFPA_1 | 1167945 | 1168706 | srtA | 0.0 | Sortase A | Exoenzyme | 98.82 | 100.00 | - |
| JFONHFPA_1 | 1346872 | 1348020 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 98.78 | 100.00 | WP_041828290 |
| JFONHFPA_1 | 1004115 | 1004846 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011227248 |
| JFONHFPA_1 | 1004115 | 1004846 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_011226048 |
| JFONHFPA_1 | 1072189 | 1072982 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.24 | 100.25 | - |
| JFONHFPA_1 | 992683 | 994098 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 98.23 | 100.00 | WP_011681165 |
| JFONHFPA_1 | 1002664 | 1003404 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 98.11 | 100.00 | WP_011226046 |
| JFONHFPA_1 | 1002664 | 1003404 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.71 | 100.00 | WP_011681174 |
| JFONHFPA_1 | 1004847 | 1006307 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 97.40 | 100.21 | WP_011226049 |
| JFONHFPA_1 | 1002669 | 1003404 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.15 | 98.13 | WP_011227246 |
| JFONHFPA_1 | 1001240 | 1002607 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 97.00 | 100.00 | WP_011226045 |
| JFONHFPA_1 | 1004847 | 1006307 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.85 | 100.21 | WP_041827043 |
| JFONHFPA_1 | 1003414 | 1004106 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.38 | 100.00 | WP_011227247 |
| JFONHFPA_1 | 1003414 | 1004106 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.38 | 100.00 | WP_011226047 |
| JFONHFPA_1 | 1342834 | 1343901 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 95.27 | 101.14 | WP_002948022 |
| JFONHFPA_1 | 1001242 | 1002607 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.58 | 99.85 | WP_011681173 |
| JFONHFPA_1 | 1003414 | 1004106 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 90.48 | 100.00 | WP_011681175 |
| JFONHFPA_1 | 1350685 | 1351959 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 89.42 | 99.92 | WP_011226331 |
| JFONHFPA_1 | 605499 | 606802 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.02 | 99.46 | WP_000022832 |
| JFONHFPA_1 | 1639451 | 1640461 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.54 | 99.41 | WP_002986042 |
| JFONHFPA_1 | 145607 | 146890 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.81 | 99.77 | WP_000107753 |
| JFONHFPA_1 | 1129689 | 1130735 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| JFONHFPA_1 | 990280 | 990863 | SPD_RS01775 | 1.09e-151 | Capsule | Immune modulation | 83.59 | 96.20 | WP_001819836 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| JFONHFPA_1 | 1171393 | 1172376 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| JFONHFPA_1 | 724770 | 725843 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| JFONHFPA_1 | 1516470 | 1518773 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| JFONHFPA_1 | 521861 | 522829 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| JFONHFPA_1 | 753090 | 755336 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| JFONHFPA_1 | 1241705 | 1243186 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.70 | 100.00 | ABJ54480 |
| JFONHFPA_1 | 63201 | 64199 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| JFONHFPA_1 | 27087 | 28058 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| JFONHFPA_1 | 1402453 | 1401302 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.06 | 99.74 | AAL00050 |
| JFONHFPA_1 | 1367090 | 1365102 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| JFONHFPA_1 | 1155194 | 1153464 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| JFONHFPA_1 | 1847813 | 1846335 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| JFONHFPA_1 | 605499 | 606800 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| JFONHFPA_1 | 1832624 | 1830732 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| JFONHFPA_1 | 758261 | 756552 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| JFONHFPA_1 | 1682849 | 1683859 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| JFONHFPA_1 | 909717 | 908356 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| JFONHFPA_1 | 1733193 | 1731301 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| JFONHFPA_1 | 591063 | 591953 | bglB | 5.27e-178 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| JFONHFPA_1 | 831108 | 830170 | SP_0676 | 2.36e-167 | transcription facot | 81.15 | 97.20 | AAK74821 |
| JFONHFPA_1 | 755528 | 756385 | metF | 1.53e-164 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| JFONHFPA_1 | 1044509 | 1043805 | covR | 4.39e-131 | responder protein | 85.53 | 100.00 | AAK71319 |
| JFONHFPA_1 | 1222730 | 1222059 | rr01 | 3.01e-124 | response regulator | 83.93 | 99.56 | CAB54566 |
| JFONHFPA_1 | 1044509 | 1043805 | walR | 1.85e-121 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| JFONHFPA_1 | 298636 | 299322 | CovR | 1.01e-117 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| JFONHFPA_1 | 762215 | 762883 | CiaR | 2.03e-117 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| JFONHFPA_1 | 762215 | 762886 | ciaR | 1.99e-115 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| JFONHFPA_1 | 64475 | 64849 | SpxA2 | 1.16e-69 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| JFONHFPA_1 | 921079 | 921480 | SpxA1 | 3.77e-66 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| JFONHFPA_1 | 147048 | 147548 | RopE (M5005_Spy_1611) | 4.94e-75 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| JFONHFPA_1 | 1516470 | 1518767 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| JFONHFPA_1 | 1718733 | 1717714 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| JFONHFPA_1 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)