Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 22 | 30 | 37.20 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| BMJANDLP_1 | 1589539 | 1590390 | rfbD | 0.0 | Capsule | Immune modulation | 95.07 | 100.00 | WP_014621820 |
| BMJANDLP_1 | 938888 | 939628 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 95.01 | 100.00 | WP_011681174 |
| BMJANDLP_1 | 939685 | 941050 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.51 | 99.85 | WP_011681173 |
| BMJANDLP_1 | 938888 | 939628 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 94.47 | 100.00 | WP_011226046 |
| BMJANDLP_1 | 935985 | 937445 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 94.11 | 100.14 | WP_011226049 |
| BMJANDLP_1 | 935985 | 937445 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 94.05 | 99.93 | WP_011681177 |
| BMJANDLP_1 | 938888 | 939623 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 94.02 | 98.13 | WP_011227246 |
| BMJANDLP_1 | 939685 | 941052 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 93.93 | 100.00 | WP_011226045 |
| BMJANDLP_1 | 1587167 | 1588438 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 93.47 | 99.76 | WP_011226331 |
| BMJANDLP_1 | 935985 | 937445 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 93.22 | 100.14 | WP_041827043 |
| BMJANDLP_1 | 1577551 | 1579335 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 93.05 | 100.00 | WP_011226325 |
| BMJANDLP_1 | 1582384 | 1583340 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 92.69 | 100.00 | WP_011226328 |
| BMJANDLP_1 | 1581591 | 1582400 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 92.35 | 100.00 | WP_002948020 |
| BMJANDLP_1 | 1580386 | 1581591 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 92.21 | 100.00 | WP_011226326 |
| BMJANDLP_1 | 1583337 | 1584485 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 91.74 | 99.91 | WP_041828290 |
| BMJANDLP_1 | 1050720 | 1052377 | fbp54 | 0.0 | FBPs | Adherence | 91.68 | 99.88 | WP_011227179 |
| BMJANDLP_1 | 937446 | 938177 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 91.67 | 100.00 | WP_011226048 |
| BMJANDLP_1 | 1579332 | 1580366 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 91.38 | 99.15 | WP_002948022 |
| BMJANDLP_1 | 937446 | 938177 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 91.26 | 100.00 | WP_011681176 |
| BMJANDLP_1 | 764834 | 765427 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 91.08 | 100.00 | WP_011226149 |
| BMJANDLP_1 | 764834 | 765427 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 90.91 | 100.00 | WP_011226149 |
| BMJANDLP_1 | 764834 | 765427 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 90.91 | 100.00 | WP_011226149 |
| BMJANDLP_1 | 937446 | 938177 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 90.71 | 100.00 | WP_011227248 |
| BMJANDLP_1 | 763965 | 764834 | rfbA | 0.0 | Capsule | Immune modulation | 90.69 | 100.00 | WP_011681286 |
| BMJANDLP_1 | 39060 | 39899 | cbpD | 0.0 | Autolysin | Exoenzyme | 90.59 | 100.00 | WP_011226733 |
| BMJANDLP_1 | 1892649 | 1893659 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 88.45 | 99.80 | WP_002986042 |
| BMJANDLP_1 | 938186 | 938878 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 88.18 | 99.86 | WP_011227247 |
| BMJANDLP_1 | 938186 | 938878 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 88.18 | 99.86 | WP_011226047 |
| BMJANDLP_1 | 587826 | 589129 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.17 | 99.54 | WP_000022832 |
| BMJANDLP_1 | 938186 | 938878 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 86.89 | 99.86 | WP_011681175 |
| BMJANDLP_1 | 1187751 | 1188512 | srtA | 0.0 | Sortase A | Exoenzyme | 84.27 | 99.87 | - |
| BMJANDLP_1 | 126295 | 127578 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.76 | 99.61 | WP_000107753 |
| BMJANDLP_1 | 765634 | 766680 | rfbB | 0.0 | Capsule | Immune modulation | 80.71 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| BMJANDLP_1 | 1191201 | 1192175 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 96.31 | 99.09 | AAK75326 |
| BMJANDLP_1 | 1179612 | 1178539 | MntE | 0.0 | manganese homeostasis | 95.53 | 99.72 | ABF32167 |
| BMJANDLP_1 | 1772302 | 1774608 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 94.41 | 99.22 | AAK74619 |
| BMJANDLP_1 | 1324838 | 1326319 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 93.32 | 100.00 | ABJ54480 |
| BMJANDLP_1 | 1160555 | 1158348 | metE | 0.0 | methionine biosynthesis enzymes | 92.94 | 98.26 | AAK74738 |
| BMJANDLP_1 | 498275 | 499243 | spr0084 | 0.0 | pathogenitcity related | 92.88 | 98.48 | AAK98888 |
| BMJANDLP_1 | 24457 | 25428 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 91.67 | 100.00 | ABF36968 |
| BMJANDLP_1 | 738583 | 740313 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 89.78 | 100.00 | AAK34199 |
| BMJANDLP_1 | 1602383 | 1600395 | uvrB | 0.0 | excinuclease ABC, B subunit | 89.44 | 100.00 | AE014259_2 |
| BMJANDLP_1 | 1630791 | 1629640 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| BMJANDLP_1 | 2132788 | 2131310 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| BMJANDLP_1 | 587826 | 589127 | Eno | 0.0 | enolase | 86.44 | 99.77 | ABP90468 |
| BMJANDLP_1 | 2117425 | 2115533 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.26 | 98.90 | ABP91129 |
| BMJANDLP_1 | 1155388 | 1157097 | PGM | 0.0 | phosphoglucomutase | 84.94 | 99.65 | ACH87041 |
| BMJANDLP_1 | 58325 | 59416 | recA | 0.0 | DNA recombination and repair | 84.64 | 95.36 | AAL00560 |
| BMJANDLP_1 | 1947909 | 1948919 | pdh | 0.0 | pyruvate dehydrogenase | 83.38 | 99.70 | ABP91006 |
| BMJANDLP_1 | 1035125 | 1036486 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.46 | 99.56 | ABP90420 |
| BMJANDLP_1 | 573418 | 574308 | bglB | 2.67e-177 | putative phospho--glucosidase | 87.88 | 99.66 | AAK33487 |
| BMJANDLP_1 | 1116202 | 1117152 | SP_0676 | 2.53e-169 | transcription facot | 81.39 | 98.45 | AAK74821 |
| BMJANDLP_1 | 1158119 | 1157262 | metF | 1.04e-168 | methionine biosynthesis enzymes | 87.76 | 99.31 | AAK74739 |
| BMJANDLP_1 | 1069199 | 1068414 | pnuC | 4.32e-149 | NAD salvage pathway importer | 87.02 | 97.40 | AAK75931 |
| BMJANDLP_1 | 1265480 | 1264809 | rr01 | 4.60e-126 | response regulator | 84.82 | 99.56 | CAB54566 |
| BMJANDLP_1 | 891221 | 891925 | covR | 9.56e-126 | responder protein | 85.53 | 100.00 | AAK71319 |
| BMJANDLP_1 | 1151421 | 1150750 | ciaR | 2.06e-124 | two component system response regulator | 86.16 | 99.12 | AIK75708 |
| BMJANDLP_1 | 1151421 | 1150753 | CiaR | 3.80e-124 | two-component response regulator | 87.44 | 99.55 | AAK74935 |
| BMJANDLP_1 | 891221 | 891925 | walR | 2.17e-119 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| BMJANDLP_1 | 266775 | 267461 | CovR | 4.69e-119 | serves to repress GAS virulence factor-encoding genes | 81.66 | 100.00 | ACE75886 |
| BMJANDLP_1 | 59592 | 59987 | SpxA2 | 2.11e-74 | transcriptional regulator | 91.67 | 100.00 | ERL21461 |
| BMJANDLP_1 | 1023656 | 1023255 | SpxA1 | 4.39e-69 | transcriptional regulator | 82.84 | 100.00 | ERL19273 |
| BMJANDLP_1 | 112674 | 113087 | GrpE | 1.67e-66 | protein grpE | 81.88 | 80.59 | ABP89267 |
| BMJANDLP_1 | 127745 | 128236 | RopE (M5005_Spy_1611) | 1.04e-71 | probable DNA-directed RNA polymerase subunit delta | 82.93 | 85.86 | AAK34603 |
| BMJANDLP_1 | 1772302 | 1774602 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.22 | 98.08 | MYN69560 |
| BMJANDLP_1 | 1984329 | 1983310 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 97.06 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| BMJANDLP_1 | 0.0 | 1.0 | 0.0 |
| BMJANDLP_2 | 1.0 | 0.0 | 1.0 |
| BMJANDLP_3 | 1.0 | 0.0 | 1.0 |
| BMJANDLP_4 | 1.0 | 0.0 | 1.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)