Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 24 | 34 | 41.62 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| HPDNJDKM_15 | 18690 | 19283 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| HPDNJDKM_55 | 12715 | 14499 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.94 | 100.00 | WP_011226325 |
| HPDNJDKM_15 | 18690 | 19283 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| HPDNJDKM_15 | 18690 | 19283 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| HPDNJDKM_55 | 17569 | 18525 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.79 | 100.00 | WP_011226328 |
| HPDNJDKM_55 | 16776 | 17585 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.75 | 100.00 | WP_002948020 |
| HPDNJDKM_13 | 11176 | 12015 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.64 | 100.00 | WP_011226733 |
| HPDNJDKM_55 | 15571 | 16776 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226326 |
| HPDNJDKM_1 | 14423 | 15790 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 99.56 | 100.00 | WP_011681173 |
| HPDNJDKM_55 | 18522 | 19670 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.56 | 100.00 | WP_041828290 |
| HPDNJDKM_55 | 23166 | 24017 | rfbD | 0.0 | Capsule | Immune modulation | 99.53 | 100.00 | WP_014621820 |
| HPDNJDKM_55 | 14496 | 15551 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.53 | 100.00 | WP_002948022 |
| HPDNJDKM_44 | 9625 | 11283 | fbp54 | 0.0 | FBPs | Adherence | 99.46 | 100.00 | WP_011227179 |
| HPDNJDKM_55 | 19779 | 20789 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 99.31 | 100.00 | WP_011226330 |
| HPDNJDKM_15 | 17821 | 18690 | rfbA | 0.0 | Capsule | Immune modulation | 99.19 | 100.00 | WP_011681286 |
| HPDNJDKM_1 | 17301 | 18029 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.90 | 99.59 | WP_011226048 |
| HPDNJDKM_66 | 72250 | 73011 | srtA | 0.0 | Sortase A | Exoenzyme | 98.29 | 100.00 | - |
| HPDNJDKM_1 | 17301 | 18029 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.22 | 99.59 | WP_011227248 |
| HPDNJDKM_55 | 20789 | 22063 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 98.12 | 100.00 | WP_011226331 |
| HPDNJDKM_1 | 17301 | 18029 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.08 | 99.59 | WP_011681176 |
| HPDNJDKM_1 | 18030 | 19490 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.40 | 100.00 | WP_011681177 |
| HPDNJDKM_1 | 15852 | 16587 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.15 | 98.13 | WP_011227246 |
| HPDNJDKM_1 | 15847 | 16587 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 96.76 | 100.00 | WP_011681174 |
| HPDNJDKM_1 | 16597 | 17289 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 96.68 | 100.00 | WP_011226047 |
| HPDNJDKM_1 | 16597 | 17289 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 96.54 | 100.00 | WP_011227247 |
| HPDNJDKM_1 | 18030 | 19490 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.51 | 100.21 | WP_011226049 |
| HPDNJDKM_1 | 18030 | 19490 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.37 | 100.21 | WP_041827043 |
| HPDNJDKM_1 | 15847 | 16587 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 96.22 | 100.00 | WP_011226046 |
| HPDNJDKM_1 | 13186 | 14181 | STU_RS14625* | 0.0 | Capsule | Immune modulation | 95.49 | 99.90 | - |
| HPDNJDKM_1 | 14427 | 15790 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.94 | 99.71 | WP_011226045 |
| HPDNJDKM_1 | 16597 | 17289 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.50 | 99.71 | WP_011681175 |
| HPDNJDKM_11 | 174927 | 176230 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.17 | 99.54 | WP_000022832 |
| HPDNJDKM_2 | 41660 | 42670 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.27 | 99.80 | WP_002986042 |
| HPDNJDKM_15 | 19712 | 20758 | rfbB | 0.0 | Capsule | Immune modulation | 80.52 | 100.00 | WP_009659423 |
| HPDNJDKM_3 | 5344 | 6627 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.50 | 99.77 | WP_000107753 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| HPDNJDKM_66 | 69563 | 68580 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| HPDNJDKM_9 | 13679 | 12606 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| HPDNJDKM_22 | 65518 | 63215 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.23 | 99.22 | AAK74619 |
| HPDNJDKM_11 | 92725 | 93693 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| HPDNJDKM_23 | 13719 | 15965 | metE | 0.0 | methionine biosynthesis enzymes | 91.86 | 100.00 | AAK74738 |
| HPDNJDKM_33 | 77721 | 76240 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.70 | 100.00 | ABJ54480 |
| HPDNJDKM_13 | 32171 | 33163 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| HPDNJDKM_28 | 6127 | 7098 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| HPDNJDKM_55 | 74906 | 73755 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| HPDNJDKM_55 | 38986 | 36998 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| HPDNJDKM_66 | 85758 | 87488 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| HPDNJDKM_10 | 27010 | 28488 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| HPDNJDKM_11 | 174927 | 176228 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| HPDNJDKM_5 | 4305 | 6197 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.89 | 98.90 | ABP91129 |
| HPDNJDKM_34 | 1905 | 196 | PGM | 0.0 | phosphoglucomutase | 83.54 | 99.65 | ACH87041 |
| HPDNJDKM_19 | 19288 | 20298 | pdh | 0.0 | pyruvate dehydrogenase | 82.79 | 99.70 | ABP91006 |
| HPDNJDKM_44 | 31087 | 29735 | mnmE | 0.0 | central tRNA-modifying GTPase | 81.90 | 98.91 | ABP90420 |
| HPDNJDKM_72 | 30871 | 32763 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| HPDNJDKM_11 | 160489 | 161379 | bglB | 1.29e-179 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| HPDNJDKM_12 | 16651 | 15713 | SP_0676 | 2.45e-169 | transcription facot | 81.15 | 97.20 | AAK74821 |
| HPDNJDKM_23 | 16157 | 17014 | metF | 7.74e-167 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| HPDNJDKM_39 | 1019 | 168 | GacA | 9.24e-167 | dTDP-4-dehydrorhamnose reductas | 82.39 | 100.00 | AAZ51220 |
| HPDNJDKM_1 | 56206 | 55502 | covR | 1.40e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| HPDNJDKM_66 | 8257 | 8928 | rr01 | 5.75e-127 | response regulator | 84.38 | 99.56 | CAB54566 |
| HPDNJDKM_1 | 56206 | 55502 | walR | 5.91e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| HPDNJDKM_4 | 48928 | 48242 | CovR | 2.86e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| HPDNJDKM_41 | 2254 | 1646 | CiaR | 9.93e-112 | two-component response regulator | 84.24 | 90.62 | AAK74935 |
| HPDNJDKM_41 | 2254 | 1646 | ciaR | 2.22e-110 | two component system response regulator | 82.76 | 89.82 | AIK75708 |
| HPDNJDKM_13 | 33460 | 33855 | SpxA2 | 6.80e-76 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| HPDNJDKM_44 | 42513 | 42914 | SpxA1 | 1.87e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| HPDNJDKM_4 | 27908 | 27621 | spr0479 | 4.05e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| HPDNJDKM_11 | 61326 | 61580 | spr1327 | 2.69e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| HPDNJDKM_5 | 37935 | 37672 | spr0175 | 2.38e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| HPDNJDKM_5 | 37132 | 36842 | spr0177 | 2.27e-37 | essential gene | 80.00 | 98.02 | AAK98981 |
| HPDNJDKM_3 | 6785 | 7285 | RopE (M5005_Spy_1611) | 1.04e-76 | probable DNA-directed RNA polymerase subunit delta | 82.04 | 87.43 | AAK34603 |
| HPDNJDKM_22 | 65518 | 63221 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.20 | 98.08 | MYN69560 |
| HPDNJDKM_72 | 45275 | 46294 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| HPDNJDKM_1 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_2 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_3 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_4 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_5 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_6 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_7 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_8 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_9 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_10 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_11 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_12 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_13 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_14 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_15 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_16 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_17 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_18 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_19 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_20 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_21 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_22 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_23 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_24 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_25 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_26 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_27 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_28 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_29 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_30 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_31 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_32 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_33 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_34 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_36 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_37 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_38 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_39 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_40 | 1.0 | 0.0 | 1.0 |
| HPDNJDKM_41 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_42 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_43 | 1.0 | 0.0 | 1.0 |
| HPDNJDKM_44 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_45 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_55 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_66 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_72 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_73 | 0.0 | 1.0 | 0.0 |
| HPDNJDKM_74 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)