Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 25 | 30 | 39.05 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| MOCKKNFI_25 | 17545 | 18414 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| MOCKKNFI_25 | 18414 | 19007 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| MOCKKNFI_10 | 124377 | 125186 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| MOCKKNFI_25 | 18414 | 19007 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| MOCKKNFI_10 | 123437 | 124393 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.79 | 100.00 | WP_011226328 |
| MOCKKNFI_10 | 122292 | 123440 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_041828290 |
| MOCKKNFI_25 | 18414 | 19007 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| MOCKKNFI_10 | 117945 | 118796 | rfbD | 0.0 | Capsule | Immune modulation | 99.65 | 100.00 | WP_014621820 |
| MOCKKNFI_49 | 1425 | 3083 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| MOCKKNFI_10 | 125186 | 126391 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226326 |
| MOCKKNFI_103 | 10124 | 10963 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| MOCKKNFI_10 | 121173 | 122183 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226330 |
| MOCKKNFI_10 | 127463 | 129247 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.44 | 100.00 | WP_011226325 |
| MOCKKNFI_10 | 126411 | 127466 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.43 | 100.00 | WP_002948022 |
| MOCKKNFI_22 | 24971 | 25732 | srtA | 0.0 | Sortase A | Exoenzyme | 98.82 | 100.00 | - |
| MOCKKNFI_36 | 504 | 1919 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 98.59 | 100.00 | WP_011681165 |
| MOCKKNFI_30 | 992 | 1785 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.36 | 100.25 | - |
| MOCKKNFI_35 | 1425 | 2156 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_011226048 |
| MOCKKNFI_35 | 1425 | 2156 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.09 | 100.00 | WP_011681176 |
| MOCKKNFI_35 | 1425 | 2156 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 97.68 | 100.00 | WP_011227248 |
| MOCKKNFI_35 | 1 | 1424 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.61 | 97.47 | WP_011681177 |
| MOCKKNFI_10 | 119899 | 121170 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 97.48 | 99.76 | WP_011226331 |
| MOCKKNFI_35 | 1 | 1424 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 97.33 | 97.66 | WP_011226049 |
| MOCKKNFI_35 | 2867 | 3607 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.17 | 100.00 | WP_011226046 |
| MOCKKNFI_35 | 1 | 1424 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.98 | 97.66 | WP_041827043 |
| MOCKKNFI_35 | 2867 | 3607 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 96.76 | 100.00 | WP_011681174 |
| MOCKKNFI_35 | 2867 | 3602 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.20 | 98.13 | WP_011227246 |
| MOCKKNFI_35 | 2165 | 2857 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.40 | 99.86 | WP_011227247 |
| MOCKKNFI_35 | 2165 | 2857 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.40 | 99.86 | WP_011226047 |
| MOCKKNFI_35 | 3664 | 5031 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 95.39 | 100.00 | WP_011226045 |
| MOCKKNFI_35 | 3664 | 5029 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.14 | 99.85 | WP_011681173 |
| MOCKKNFI_35 | 2165 | 2857 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.47 | 100.00 | WP_011681175 |
| MOCKKNFI_78 | 32968 | 34271 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| MOCKKNFI_89 | 21223 | 22233 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.54 | 99.41 | WP_002986042 |
| MOCKKNFI_97 | 60830 | 62113 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.65 | 99.77 | WP_000107753 |
| MOCKKNFI_25 | 19436 | 20482 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| MOCKKNFI_22 | 22284 | 21301 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| MOCKKNFI_89 | 13291 | 12218 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| MOCKKNFI_79 | 60940 | 59972 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| MOCKKNFI_94 | 15666 | 13363 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.84 | 99.22 | AAK74619 |
| MOCKKNFI_18 | 13141 | 11660 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| MOCKKNFI_73 | 11305 | 9059 | metE | 0.0 | methionine biosynthesis enzymes | 91.72 | 100.00 | AAK74738 |
| MOCKKNFI_102 | 1998 | 1000 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| MOCKKNFI_103 | 27446 | 26475 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| MOCKKNFI_10 | 66882 | 68033 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| MOCKKNFI_10 | 102975 | 104963 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| MOCKKNFI_1 | 27137 | 28615 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| MOCKKNFI_78 | 34271 | 32970 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| MOCKKNFI_1 | 42325 | 44217 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| MOCKKNFI_73 | 6221 | 7876 | PGM | 0.0 | phosphoglucomutase | 83.72 | 96.50 | ACH87041 |
| MOCKKNFI_61 | 2109 | 1099 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| MOCKKNFI_28 | 26127 | 28019 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| MOCKKNFI_78 | 48706 | 47816 | bglB | 4.07e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| MOCKKNFI_73 | 8867 | 8010 | metF | 2.11e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| MOCKKNFI_31 | 4815 | 5519 | covR | 2.25e-133 | responder protein | 85.53 | 100.00 | AAK71319 |
| MOCKKNFI_18 | 54377 | 55048 | rr01 | 1.19e-125 | response regulator | 83.93 | 99.56 | CAB54566 |
| MOCKKNFI_31 | 4815 | 5519 | walR | 9.45e-124 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| MOCKKNFI_91 | 8185 | 7499 | CovR | 1.30e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| MOCKKNFI_73 | 2267 | 1599 | CiaR | 2.80e-119 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| MOCKKNFI_73 | 2267 | 1596 | ciaR | 2.76e-117 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| MOCKKNFI_102 | 724 | 350 | SpxA2 | 8.99e-72 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| MOCKKNFI_47 | 9901 | 9500 | SpxA1 | 6.41e-68 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| MOCKKNFI_89 | 67509 | 67222 | spr0479 | 6.34e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| MOCKKNFI_82 | 18277 | 18023 | spr1327 | 1.13e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| MOCKKNFI_1 | 84914 | 84651 | spr0175 | 4.58e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| MOCKKNFI_1 | 84087 | 83821 | spr0177 | 8.09e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| MOCKKNFI_97 | 60672 | 60172 | RopE (M5005_Spy_1611) | 1.77e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| MOCKKNFI_94 | 15666 | 13369 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.81 | 98.08 | MYN69560 |
| MOCKKNFI_28 | 40599 | 41618 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| MOCKKNFI_1 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_2 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_5 | 1.0 | 0.0 | 1.0 |
| MOCKKNFI_8 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_9 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_10 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_11 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_12 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_14 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_15 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_16 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_17 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_18 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_20 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_22 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_23 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_24 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_25 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_27 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_28 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_29 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_30 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_31 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_33 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_34 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_35 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_36 | 1.0 | 0.0 | 1.0 |
| MOCKKNFI_37 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_39 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_40 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_46 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_47 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_48 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_49 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_50 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_53 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_54 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_55 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_57 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_58 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_61 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_71 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_72 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_73 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_74 | 1.0 | 0.0 | 1.0 |
| MOCKKNFI_75 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_76 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_77 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_78 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_79 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_80 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_82 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_83 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_84 | 1.0 | 0.0 | 1.0 |
| MOCKKNFI_85 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_86 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_87 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_88 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_89 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_90 | 1.0 | 0.0 | 1.0 |
| MOCKKNFI_91 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_92 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_93 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_94 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_95 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_97 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_98 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_102 | 0.0 | 1.0 | 0.0 |
| MOCKKNFI_103 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)