Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 23 | 34 | 41.05 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| ALGMGLFE_1 | 20731 | 21570 | cbpD | 0.0 | Autolysin | Exoenzyme | 100.00 | 100.00 | WP_011226733 |
| ALGMGLFE_37 | 56905 | 57774 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| ALGMGLFE_37 | 56312 | 56905 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| ALGMGLFE_20 | 27899 | 28867 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681443 |
| ALGMGLFE_37 | 56312 | 56905 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| ALGMGLFE_37 | 56312 | 56905 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| ALGMGLFE_15 | 13081 | 14739 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| ALGMGLFE_20 | 28885 | 29862 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.28 | 100.00 | WP_011681444 |
| ALGMGLFE_17 | 16312 | 17073 | srtA | 0.0 | Sortase A | Exoenzyme | 99.21 | 100.00 | - |
| ALGMGLFE_20 | 26066 | 26836 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 99.09 | 99.10 | WP_011681440 |
| ALGMGLFE_16 | 64344 | 65757 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 98.52 | 99.93 | WP_011681165 |
| ALGMGLFE_20 | 27182 | 27897 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.46 | 99.86 | WP_011681442 |
| ALGMGLFE_16 | 89199 | 89939 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 98.25 | 100.00 | WP_011681174 |
| ALGMGLFE_16 | 89199 | 89939 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 98.11 | 100.00 | WP_011226046 |
| ALGMGLFE_16 | 159778 | 160567 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 97.98 | 99.75 | - |
| ALGMGLFE_16 | 90650 | 91381 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 97.95 | 100.00 | WP_011681176 |
| ALGMGLFE_16 | 90650 | 91381 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 97.81 | 100.00 | WP_011227248 |
| ALGMGLFE_16 | 89204 | 89939 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.69 | 98.13 | WP_011227246 |
| ALGMGLFE_16 | 90650 | 91381 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.68 | 100.00 | WP_011226048 |
| ALGMGLFE_16 | 91382 | 92836 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 97.39 | 100.00 | WP_011226049 |
| ALGMGLFE_20 | 31236 | 32087 | rfbD | 0.0 | Capsule | Immune modulation | 97.07 | 100.00 | WP_014621820 |
| ALGMGLFE_16 | 91382 | 92836 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.84 | 100.00 | WP_041827043 |
| ALGMGLFE_16 | 89949 | 90641 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 96.69 | 99.86 | WP_011226047 |
| ALGMGLFE_20 | 29859 | 31117 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 96.43 | 99.92 | WP_011681445 |
| ALGMGLFE_16 | 89949 | 90641 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 96.39 | 100.00 | WP_011227247 |
| ALGMGLFE_16 | 91382 | 92836 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 96.37 | 99.79 | WP_011681177 |
| ALGMGLFE_16 | 87775 | 89142 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 95.10 | 100.00 | WP_011226045 |
| ALGMGLFE_16 | 87777 | 89142 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.07 | 99.85 | WP_011681173 |
| ALGMGLFE_3 | 17971 | 22922 | SSU98_0978 | 0.0 | Agglutinin receptor | Adherence | 92.97 | 99.96 | YP_001200536 |
| ALGMGLFE_3 | 17971 | 22922 | SSU05_0965 | 0.0 | Agglutinin receptor | Adherence | 92.95 | 99.96 | YP_001198331 |
| ALGMGLFE_3 | 18028 | 22922 | SAG_RS09105 | 0.0 | Agglutinin receptor | Adherence | 92.89 | 99.96 | WP_000167699 |
| ALGMGLFE_16 | 89949 | 90641 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.75 | 100.00 | WP_011681175 |
| ALGMGLFE_5 | 39495 | 40798 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| ALGMGLFE_22 | 71768 | 72778 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.55 | 99.90 | WP_002986042 |
| ALGMGLFE_34 | 7437 | 8720 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.81 | 99.77 | WP_000107753 |
| ALGMGLFE_37 | 54837 | 55883 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| ALGMGLFE_17 | 19760 | 20743 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| ALGMGLFE_7 | 53419 | 54492 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| ALGMGLFE_3 | 18007 | 22917 | B9H01_RS04765 | 0.0 | glucan-binding protein | 93.53 | 99.63 | AUS90958 |
| ALGMGLFE_4 | 18495 | 19463 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| ALGMGLFE_20 | 197407 | 199710 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| ALGMGLFE_8 | 6452 | 8698 | metE | 0.0 | methionine biosynthesis enzymes | 91.86 | 100.00 | AAK74738 |
| ALGMGLFE_17 | 102155 | 103636 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.70 | 100.00 | ABJ54480 |
| ALGMGLFE_1 | 41588 | 42580 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| ALGMGLFE_1 | 4249 | 5220 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| ALGMGLFE_20 | 74107 | 72956 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| ALGMGLFE_20 | 45386 | 43398 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| ALGMGLFE_17 | 3562 | 1832 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| ALGMGLFE_29 | 27773 | 26295 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.22 | 100.00 | ADE32434 |
| ALGMGLFE_5 | 39495 | 40796 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| ALGMGLFE_29 | 12584 | 10692 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| ALGMGLFE_8 | 11623 | 9914 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| ALGMGLFE_25 | 18866 | 19876 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| ALGMGLFE_16 | 1827 | 466 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| ALGMGLFE_25 | 69202 | 67310 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| ALGMGLFE_5 | 25056 | 25946 | bglB | 4.94e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| ALGMGLFE_13 | 11842 | 10904 | SP_0676 | 1.57e-169 | transcription facot | 81.47 | 97.20 | AAK74821 |
| ALGMGLFE_8 | 8890 | 9747 | metF | 1.42e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| ALGMGLFE_16 | 129678 | 128974 | covR | 2.01e-131 | responder protein | 85.11 | 100.00 | AAK71319 |
| ALGMGLFE_17 | 74050 | 73379 | rr01 | 2.16e-125 | response regulator | 83.93 | 99.56 | CAB54566 |
| ALGMGLFE_16 | 129678 | 128974 | walR | 8.56e-122 | DNA-binding response regulator | 81.70 | 100.00 | ANC99504 |
| ALGMGLFE_37 | 38411 | 39097 | CovR | 1.26e-119 | serves to repress GAS virulence factor-encoding genes | 81.22 | 100.00 | ACE75886 |
| ALGMGLFE_8 | 15577 | 16245 | CiaR | 1.53e-118 | two-component response regulator | 83.86 | 99.55 | AAK74935 |
| ALGMGLFE_8 | 15577 | 16248 | ciaR | 2.24e-116 | two component system response regulator | 81.70 | 99.12 | AIK75708 |
| ALGMGLFE_1 | 42877 | 43272 | SpxA2 | 8.70e-76 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| ALGMGLFE_38 | 13254 | 13541 | spr0479 | 2.97e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| ALGMGLFE_41 | 61226 | 61480 | spr1327 | 9.97e-46 | essential gene | 95.29 | 100.00 | AAL00131 |
| ALGMGLFE_28 | 5771 | 6034 | spr0175 | 1.04e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| ALGMGLFE_28 | 6598 | 6864 | spr0177 | 2.27e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| ALGMGLFE_34 | 8878 | 9378 | RopE (M5005_Spy_1611) | 3.33e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| ALGMGLFE_20 | 197407 | 199704 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| ALGMGLFE_17 | 120498 | 119302 | AUS90997 (B9H01_RS07385) | 0.0 | site-specific integrase | 98.25 | 100.00 | AUS90997 |
| ALGMGLFE_25 | 54729 | 53710 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| ALGMGLFE_1 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_2 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_3 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_4 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_5 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_6 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_7 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_8 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_9 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_10 | 1.0 | 0.0 | 1.0 |
| ALGMGLFE_11 | 1.0 | 0.0 | 1.0 |
| ALGMGLFE_12 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_13 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_14 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_15 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_16 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_17 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_18 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_19 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_20 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_21 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_22 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_23 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_24 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_25 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_26 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_27 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_28 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_29 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_30 | 1.0 | 0.0 | 1.0 |
| ALGMGLFE_32 | 1.0 | 0.0 | 1.0 |
| ALGMGLFE_33 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_34 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_35 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_36 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_37 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_38 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_39 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_40 | 0.0 | 1.0 | 0.0 |
| ALGMGLFE_41 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)