Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 25 | 33 | 41.40 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| JIOHCKLC_16 | 2218 | 3087 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| JIOHCKLC_16 | 1625 | 2218 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| JIOHCKLC_20 | 86798 | 87607 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| JIOHCKLC_16 | 1625 | 2218 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| JIOHCKLC_20 | 87591 | 88547 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.79 | 100.00 | WP_011226328 |
| JIOHCKLC_20 | 88544 | 89692 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_041828290 |
| JIOHCKLC_16 | 1625 | 2218 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| JIOHCKLC_20 | 93188 | 94039 | rfbD | 0.0 | Capsule | Immune modulation | 99.65 | 100.00 | WP_014621820 |
| JIOHCKLC_6 | 25547 | 27205 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| JIOHCKLC_20 | 85593 | 86798 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226326 |
| JIOHCKLC_20 | 82737 | 84521 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226325 |
| JIOHCKLC_20 | 89801 | 90811 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226330 |
| JIOHCKLC_20 | 84518 | 85573 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.34 | 100.00 | WP_002948022 |
| JIOHCKLC_5 | 657 | 2072 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 99.15 | 100.00 | WP_011681165 |
| JIOHCKLC_17 | 14648 | 15409 | srtA | 0.0 | Sortase A | Exoenzyme | 98.82 | 100.00 | - |
| JIOHCKLC_1 | 21037 | 21876 | cbpD | 0.0 | Autolysin | Exoenzyme | 98.69 | 100.00 | WP_011226733 |
| JIOHCKLC_13 | 19266 | 20054 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.48 | 99.75 | - |
| JIOHCKLC_3 | 111274 | 112005 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_011226048 |
| JIOHCKLC_3 | 111274 | 112005 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.09 | 100.00 | WP_011681176 |
| JIOHCKLC_3 | 111274 | 112005 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 97.68 | 100.00 | WP_011227248 |
| JIOHCKLC_20 | 90814 | 92085 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 97.48 | 99.76 | WP_011226331 |
| JIOHCKLC_3 | 109813 | 111273 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.06 | 100.00 | WP_011681177 |
| JIOHCKLC_3 | 112716 | 113456 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.03 | 100.00 | WP_011681174 |
| JIOHCKLC_3 | 112716 | 113456 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 96.36 | 100.00 | WP_011226046 |
| JIOHCKLC_3 | 109813 | 111273 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.30 | 100.21 | WP_011226049 |
| JIOHCKLC_3 | 109813 | 111273 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.17 | 100.21 | WP_041827043 |
| JIOHCKLC_3 | 112716 | 113451 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 96.06 | 98.13 | WP_011227246 |
| JIOHCKLC_3 | 113513 | 114876 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 95.53 | 99.71 | WP_011226045 |
| JIOHCKLC_3 | 112014 | 112706 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.40 | 99.86 | WP_011227247 |
| JIOHCKLC_3 | 112014 | 112706 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.40 | 99.86 | WP_011226047 |
| JIOHCKLC_3 | 113513 | 114880 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.52 | 99.93 | WP_011681173 |
| JIOHCKLC_3 | 112014 | 112706 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 89.47 | 100.00 | WP_011681175 |
| JIOHCKLC_35 | 95745 | 97048 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| JIOHCKLC_24 | 312 | 1322 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.46 | 99.80 | WP_002986042 |
| JIOHCKLC_20 | 6574 | 7857 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| JIOHCKLC_16 | 150 | 1196 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| JIOHCKLC_17 | 18096 | 19079 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| JIOHCKLC_3 | 24961 | 26034 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| JIOHCKLC_20 | 259006 | 261309 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| JIOHCKLC_35 | 12110 | 13078 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| JIOHCKLC_18 | 52059 | 53540 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| JIOHCKLC_3 | 53339 | 55585 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| JIOHCKLC_1 | 40667 | 41659 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| JIOHCKLC_1 | 4551 | 5522 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| JIOHCKLC_20 | 145313 | 144162 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| JIOHCKLC_20 | 109009 | 107021 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| JIOHCKLC_17 | 1901 | 171 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| JIOHCKLC_27 | 62970 | 61492 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| JIOHCKLC_35 | 95745 | 97046 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| JIOHCKLC_27 | 47781 | 45889 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| JIOHCKLC_11 | 6192 | 7901 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| JIOHCKLC_26 | 21558 | 22568 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| JIOHCKLC_5 | 66801 | 68162 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| JIOHCKLC_26 | 71925 | 70033 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| JIOHCKLC_35 | 81309 | 82199 | bglB | 4.95e-179 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| JIOHCKLC_7 | 39729 | 40664 | SP_0676 | 2.03e-169 | transcription facot | 81.73 | 96.89 | AAK74821 |
| JIOHCKLC_3 | 55777 | 56634 | metF | 1.07e-165 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| JIOHCKLC_3 | 72958 | 73662 | covR | 3.07e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| JIOHCKLC_18 | 33084 | 32413 | rr01 | 2.12e-125 | response regulator | 83.93 | 99.56 | CAB54566 |
| JIOHCKLC_3 | 72958 | 73662 | walR | 1.29e-122 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| JIOHCKLC_11 | 2238 | 1570 | CiaR | 8.66e-120 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| JIOHCKLC_32 | 73687 | 74373 | CovR | 6.72e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| JIOHCKLC_11 | 2238 | 1567 | ciaR | 8.52e-118 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| JIOHCKLC_1 | 41956 | 42351 | SpxA2 | 8.51e-76 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| JIOHCKLC_5 | 55438 | 55037 | SpxA1 | 1.39e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| JIOHCKLC_32 | 96066 | 96353 | spr0479 | 9.30e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| JIOHCKLC_33 | 129078 | 129332 | spr1327 | 1.40e-44 | essential gene | 94.12 | 100.00 | AAL00131 |
| JIOHCKLC_27 | 14138 | 14401 | spr0175 | 3.53e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| JIOHCKLC_27 | 14965 | 15231 | spr0177 | 7.71e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| JIOHCKLC_20 | 8015 | 8515 | RopE (M5005_Spy_1611) | 7.30e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| JIOHCKLC_20 | 259006 | 261303 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| JIOHCKLC_26 | 57469 | 56450 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| JIOHCKLC_1 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_2 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_3 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_4 | 1.0 | 0.0 | 1.0 |
| JIOHCKLC_5 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_6 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_7 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_8 | 1.0 | 0.0 | 1.0 |
| JIOHCKLC_9 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_10 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_11 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_12 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_13 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_14 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_15 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_16 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_17 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_18 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_19 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_20 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_21 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_22 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_23 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_24 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_25 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_26 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_27 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_29 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_30 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_31 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_32 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_33 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_34 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_35 | 0.0 | 1.0 | 0.0 |
| JIOHCKLC_36 | 1.0 | 0.0 | 1.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)