Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 24 | 33 | 40.80 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| KJGEAKFH_8 | 153359 | 154228 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| KJGEAKFH_8 | 152766 | 153359 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| KJGEAKFH_10 | 81410 | 82219 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.88 | 100.00 | WP_002948020 |
| KJGEAKFH_8 | 152766 | 153359 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| KJGEAKFH_10 | 82203 | 83159 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.79 | 100.00 | WP_011226328 |
| KJGEAKFH_10 | 83156 | 84304 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.74 | 100.00 | WP_041828290 |
| KJGEAKFH_8 | 152766 | 153359 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| KJGEAKFH_25 | 1117 | 2260 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 99.56 | 100.00 | - |
| KJGEAKFH_1 | 20103 | 20942 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| KJGEAKFH_10 | 80205 | 81410 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226326 |
| KJGEAKFH_10 | 79130 | 80185 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.43 | 100.00 | WP_002948022 |
| KJGEAKFH_5 | 65539 | 67197 | fbp54 | 0.0 | FBPs | Adherence | 99.34 | 100.00 | WP_011227179 |
| KJGEAKFH_10 | 77349 | 79133 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.33 | 100.00 | WP_011226325 |
| KJGEAKFH_8 | 29955 | 30686 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 99.32 | 100.00 | WP_011681176 |
| KJGEAKFH_8 | 29955 | 30686 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.77 | 100.00 | WP_011226048 |
| KJGEAKFH_8 | 29955 | 30686 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.63 | 100.00 | WP_011227248 |
| KJGEAKFH_8 | 188126 | 188887 | srtA | 0.0 | Sortase A | Exoenzyme | 97.77 | 100.00 | - |
| KJGEAKFH_8 | 30687 | 32147 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.67 | 100.00 | WP_011681177 |
| KJGEAKFH_10 | 87806 | 88657 | rfbD | 0.0 | Capsule | Immune modulation | 96.60 | 100.00 | WP_014621820 |
| KJGEAKFH_8 | 30687 | 32147 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.51 | 100.21 | WP_011226049 |
| KJGEAKFH_8 | 28504 | 29244 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 95.82 | 100.00 | WP_011681174 |
| KJGEAKFH_8 | 30687 | 32147 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.69 | 100.21 | WP_041827043 |
| KJGEAKFH_8 | 28504 | 29244 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 95.41 | 100.00 | WP_011226046 |
| KJGEAKFH_8 | 28509 | 29244 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 95.11 | 98.13 | WP_011227246 |
| KJGEAKFH_8 | 29254 | 29946 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.09 | 100.00 | WP_011226047 |
| KJGEAKFH_8 | 29254 | 29946 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 94.81 | 100.00 | WP_011227247 |
| KJGEAKFH_8 | 27080 | 28447 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.74 | 99.93 | WP_011226045 |
| KJGEAKFH_8 | 27082 | 28447 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.37 | 99.71 | WP_011681173 |
| KJGEAKFH_8 | 29254 | 29946 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 92.35 | 100.00 | WP_011681175 |
| KJGEAKFH_10 | 85429 | 86703 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 91.14 | 100.00 | WP_011226331 |
| KJGEAKFH_27 | 39253 | 40556 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| KJGEAKFH_13 | 184 | 1194 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 87.36 | 99.80 | WP_002986042 |
| KJGEAKFH_21 | 6424 | 7707 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.73 | 99.77 | WP_000107753 |
| KJGEAKFH_8 | 151291 | 152337 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| KJGEAKFH_8 | 18369 | 18952 | SPD_RS01775 | 1.38e-147 | Capsule | Immune modulation | 83.08 | 96.20 | WP_001819836 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| KJGEAKFH_8 | 191574 | 192557 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| KJGEAKFH_2 | 27707 | 28780 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| KJGEAKFH_26 | 13296 | 14264 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| KJGEAKFH_11 | 92637 | 94940 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| KJGEAKFH_9 | 31050 | 32531 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| KJGEAKFH_2 | 48210 | 50456 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| KJGEAKFH_1 | 49364 | 50362 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| KJGEAKFH_1 | 3619 | 4590 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| KJGEAKFH_10 | 139394 | 138243 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| KJGEAKFH_10 | 103627 | 101639 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| KJGEAKFH_8 | 175377 | 173647 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.69 | 100.00 | AAK34199 |
| KJGEAKFH_23 | 60072 | 58594 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| KJGEAKFH_27 | 39253 | 40554 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| KJGEAKFH_23 | 44883 | 42991 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| KJGEAKFH_2 | 53381 | 51672 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| KJGEAKFH_14 | 21265 | 22275 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| KJGEAKFH_7 | 1502 | 141 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| KJGEAKFH_14 | 73308 | 71416 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| KJGEAKFH_27 | 24818 | 25708 | bglB | 8.08e-180 | putative phospho--glucosidase | 88.89 | 99.66 | AAK33487 |
| KJGEAKFH_5 | 11765 | 10827 | SP_0676 | 1.24e-168 | transcription facot | 81.15 | 97.20 | AAK74821 |
| KJGEAKFH_2 | 50648 | 51505 | metF | 7.53e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| KJGEAKFH_8 | 68967 | 68263 | covR | 5.50e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| KJGEAKFH_9 | 12075 | 11404 | rr01 | 7.03e-126 | response regulator | 83.93 | 99.56 | CAB54566 |
| KJGEAKFH_2 | 57335 | 58003 | CiaR | 4.14e-124 | two-component response regulator | 87.00 | 99.55 | AAK74935 |
| KJGEAKFH_8 | 68967 | 68263 | walR | 2.31e-122 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| KJGEAKFH_2 | 57335 | 58006 | ciaR | 4.41e-122 | two component system response regulator | 84.82 | 99.12 | AIK75708 |
| KJGEAKFH_23 | 179318 | 180004 | CovR | 1.23e-118 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| KJGEAKFH_1 | 50638 | 51012 | SpxA2 | 3.18e-71 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| KJGEAKFH_7 | 12920 | 13321 | SpxA1 | 1.02e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| KJGEAKFH_23 | 201701 | 201988 | spr0479 | 1.74e-48 | essential gene | 86.46 | 98.97 | AAK99283 |
| KJGEAKFH_24 | 121770 | 122024 | spr1327 | 2.18e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| KJGEAKFH_23 | 11255 | 11518 | spr0175 | 8.76e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| KJGEAKFH_23 | 12082 | 12348 | spr0177 | 1.92e-33 | essential gene | 84.27 | 88.12 | AAK98981 |
| KJGEAKFH_21 | 7865 | 8365 | RopE (M5005_Spy_1611) | 1.78e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| KJGEAKFH_11 | 92637 | 94934 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| KJGEAKFH_14 | 58836 | 57817 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| KJGEAKFH_1 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_2 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_3 | 1.0 | 0.0 | 1.0 |
| KJGEAKFH_4 | 1.0 | 0.0 | 1.0 |
| KJGEAKFH_5 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_6 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_7 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_8 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_9 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_10 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_11 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_12 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_13 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_14 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_15 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_16 | 1.0 | 0.0 | 1.0 |
| KJGEAKFH_17 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_19 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_20 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_21 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_22 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_23 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_24 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_25 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_26 | 0.0 | 1.0 | 0.0 |
| KJGEAKFH_27 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)