Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 25 | 33 | 41.40 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| DGCIJIBN_14 | 1615 | 2208 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| DGCIJIBN_10 | 139278 | 140738 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 99.93 | 100.00 | WP_011681177 |
| DGCIJIBN_14 | 1615 | 2208 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| DGCIJIBN_16 | 88903 | 89712 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.75 | 100.00 | WP_002948020 |
| DGCIJIBN_14 | 2208 | 3077 | rfbA | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011681286 |
| DGCIJIBN_14 | 1615 | 2208 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| DGCIJIBN_10 | 20636 | 22294 | fbp54 | 0.0 | FBPs | Adherence | 99.64 | 100.00 | WP_011227179 |
| DGCIJIBN_16 | 89696 | 90652 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226328 |
| DGCIJIBN_1 | 20810 | 21649 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| DGCIJIBN_16 | 84830 | 86614 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.44 | 100.00 | WP_011226325 |
| DGCIJIBN_16 | 87698 | 88903 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.17 | 100.00 | WP_011226326 |
| DGCIJIBN_16 | 96839 | 97690 | rfbD | 0.0 | Capsule | Immune modulation | 99.06 | 100.00 | WP_014621820 |
| DGCIJIBN_10 | 138546 | 139277 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.91 | 100.00 | WP_011681176 |
| DGCIJIBN_15 | 14754 | 15515 | srtA | 0.0 | Sortase A | Exoenzyme | 98.82 | 100.00 | - |
| DGCIJIBN_16 | 90649 | 91797 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 98.78 | 100.00 | WP_041828290 |
| DGCIJIBN_10 | 138546 | 139277 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 98.50 | 100.00 | WP_011227248 |
| DGCIJIBN_10 | 138546 | 139277 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 98.36 | 100.00 | WP_011226048 |
| DGCIJIBN_11 | 64615 | 65408 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 98.24 | 100.25 | - |
| DGCIJIBN_10 | 127114 | 128529 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 98.23 | 100.00 | WP_011681165 |
| DGCIJIBN_10 | 137095 | 137835 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 98.11 | 100.00 | WP_011226046 |
| DGCIJIBN_10 | 137095 | 137835 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.71 | 100.00 | WP_011681174 |
| DGCIJIBN_10 | 139278 | 140738 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 97.40 | 100.21 | WP_011226049 |
| DGCIJIBN_10 | 137100 | 137835 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.15 | 98.13 | WP_011227246 |
| DGCIJIBN_10 | 135671 | 137038 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 97.00 | 100.00 | WP_011226045 |
| DGCIJIBN_10 | 139278 | 140738 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.85 | 100.21 | WP_041827043 |
| DGCIJIBN_10 | 137845 | 138537 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 95.38 | 100.00 | WP_011227247 |
| DGCIJIBN_10 | 137845 | 138537 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 95.38 | 100.00 | WP_011226047 |
| DGCIJIBN_16 | 86611 | 87678 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 95.27 | 101.14 | WP_002948022 |
| DGCIJIBN_10 | 135673 | 137038 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.58 | 99.85 | WP_011681173 |
| DGCIJIBN_10 | 137845 | 138537 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 90.48 | 100.00 | WP_011681175 |
| DGCIJIBN_16 | 94462 | 95736 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 89.42 | 99.92 | WP_011226331 |
| DGCIJIBN_34 | 96948 | 98251 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.02 | 99.46 | WP_000022832 |
| DGCIJIBN_18 | 105953 | 106963 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.54 | 99.41 | WP_002986042 |
| DGCIJIBN_29 | 6404 | 7687 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.81 | 99.77 | WP_000107753 |
| DGCIJIBN_14 | 140 | 1186 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| DGCIJIBN_10 | 124711 | 125294 | SPD_RS01775 | 8.28e-153 | Capsule | Immune modulation | 83.59 | 96.20 | WP_001819836 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| DGCIJIBN_15 | 18202 | 19185 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| DGCIJIBN_5 | 59611 | 60684 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| DGCIJIBN_17 | 138603 | 140906 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| DGCIJIBN_34 | 13310 | 14278 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| DGCIJIBN_5 | 87931 | 90177 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| DGCIJIBN_15 | 88514 | 89995 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 91.70 | 100.00 | ABJ54480 |
| DGCIJIBN_1 | 40441 | 41439 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| DGCIJIBN_1 | 4327 | 5298 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| DGCIJIBN_17 | 24586 | 23435 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.06 | 99.74 | AAL00050 |
| DGCIJIBN_16 | 110867 | 108879 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| DGCIJIBN_15 | 2003 | 273 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 88.04 | 100.00 | AAK34199 |
| DGCIJIBN_25 | 28124 | 26646 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| DGCIJIBN_34 | 96948 | 98249 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| DGCIJIBN_25 | 12935 | 11043 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| DGCIJIBN_5 | 93102 | 91393 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| DGCIJIBN_20 | 18096 | 19106 | pdh | 0.0 | pyruvate dehydrogenase | 83.09 | 99.70 | ABP91006 |
| DGCIJIBN_10 | 44148 | 42787 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| DGCIJIBN_20 | 68440 | 66548 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| DGCIJIBN_34 | 82512 | 83402 | bglB | 3.39e-179 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| DGCIJIBN_9 | 18105 | 17167 | SP_0676 | 6.47e-169 | transcription facot | 81.15 | 97.20 | AAK74821 |
| DGCIJIBN_5 | 90369 | 91226 | metF | 8.15e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| DGCIJIBN_11 | 36935 | 36231 | covR | 1.57e-132 | responder protein | 85.53 | 100.00 | AAK71319 |
| DGCIJIBN_15 | 69539 | 68868 | rr01 | 1.64e-125 | response regulator | 83.93 | 99.56 | CAB54566 |
| DGCIJIBN_11 | 36935 | 36231 | walR | 6.61e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| DGCIJIBN_5 | 97056 | 97724 | CiaR | 1.08e-118 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| DGCIJIBN_29 | 159433 | 160119 | CovR | 1.12e-118 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| DGCIJIBN_5 | 97056 | 97727 | ciaR | 1.06e-116 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| DGCIJIBN_1 | 41715 | 42089 | SpxA2 | 2.63e-71 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| DGCIJIBN_10 | 55510 | 55911 | SpxA1 | 2.86e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| DGCIJIBN_29 | 181814 | 182101 | spr0479 | 1.59e-48 | essential gene | 86.46 | 98.97 | AAK99283 |
| DGCIJIBN_30 | 120940 | 121194 | spr1327 | 1.89e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| DGCIJIBN_24 | 15657 | 15920 | spr0175 | 1.41e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| DGCIJIBN_24 | 16484 | 16750 | spr0177 | 3.08e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| DGCIJIBN_29 | 7845 | 8345 | RopE (M5005_Spy_1611) | 5.50e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| DGCIJIBN_17 | 138603 | 140900 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| DGCIJIBN_20 | 53980 | 52961 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| DGCIJIBN_1 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_2 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_3 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_4 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_5 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_6 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_7 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_8 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_9 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_10 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_11 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_12 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_13 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_14 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_15 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_16 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_17 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_18 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_19 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_20 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_21 | 1.0 | 0.0 | 1.0 |
| DGCIJIBN_22 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_23 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_24 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_25 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_27 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_28 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_29 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_30 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_31 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_32 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_33 | 0.0 | 1.0 | 0.0 |
| DGCIJIBN_34 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)