Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 22 | 33 | 39.66 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| BNPCIHNK_14 | 9521 | 10390 | rfbA | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681286 |
| BNPCIHNK_14 | 8928 | 9521 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011226149 |
| BNPCIHNK_15 | 70195 | 71454 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 100.00 | 100.00 | WP_011681445 |
| BNPCIHNK_14 | 8928 | 9521 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.83 | 100.00 | WP_011226149 |
| BNPCIHNK_14 | 8928 | 9521 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| BNPCIHNK_15 | 69222 | 70198 | STER_RS07095 | 0.0 | Capsule | Immune modulation | 99.59 | 99.90 | WP_011681444 |
| BNPCIHNK_38 | 5735 | 7393 | fbp54 | 0.0 | FBPs | Adherence | 99.58 | 100.00 | WP_011227179 |
| BNPCIHNK_35 | 9050 | 9889 | cbpD | 0.0 | Autolysin | Exoenzyme | 99.52 | 100.00 | WP_011226733 |
| BNPCIHNK_15 | 68236 | 69204 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 99.28 | 100.00 | WP_011681443 |
| BNPCIHNK_11 | 24853 | 25614 | srtA | 0.0 | Sortase A | Exoenzyme | 99.21 | 100.00 | - |
| BNPCIHNK_23 | 7390 | 8121 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 99.18 | 100.00 | WP_011226048 |
| BNPCIHNK_23 | 7390 | 8121 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 99.04 | 100.00 | WP_011227248 |
| BNPCIHNK_23 | 7390 | 8121 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 98.91 | 100.00 | WP_011681176 |
| BNPCIHNK_15 | 67519 | 68234 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 98.32 | 99.86 | WP_011681442 |
| BNPCIHNK_21 | 21598 | 22393 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 97.99 | 100.51 | - |
| BNPCIHNK_15 | 66403 | 67173 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 97.92 | 99.23 | WP_011681440 |
| BNPCIHNK_49 | 375 | 1790 | STER_RS05250 | 0.0 | Capsule | Immune modulation | 97.88 | 100.00 | WP_011681165 |
| BNPCIHNK_23 | 8122 | 9582 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.67 | 100.00 | WP_011681177 |
| BNPCIHNK_15 | 71573 | 72424 | rfbD | 0.0 | Capsule | Immune modulation | 97.30 | 100.00 | WP_014621820 |
| BNPCIHNK_23 | 6689 | 7381 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 97.11 | 100.00 | WP_011226047 |
| BNPCIHNK_23 | 6689 | 7381 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 96.97 | 100.00 | WP_011227247 |
| BNPCIHNK_23 | 8122 | 9582 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 96.65 | 100.21 | WP_011226049 |
| BNPCIHNK_23 | 8122 | 9582 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.96 | 100.21 | WP_041827043 |
| BNPCIHNK_23 | 4499 | 5864 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 95.46 | 99.85 | WP_011681173 |
| BNPCIHNK_23 | 4497 | 5864 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.08 | 100.00 | WP_011226045 |
| BNPCIHNK_23 | 5921 | 6679 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 93.41 | 100.94 | WP_011681174 |
| BNPCIHNK_23 | 5921 | 6679 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 93.02 | 100.94 | WP_011226046 |
| BNPCIHNK_23 | 5926 | 6679 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 92.71 | 99.07 | WP_011227246 |
| BNPCIHNK_23 | 6689 | 7381 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 90.06 | 99.86 | WP_011681175 |
| BNPCIHNK_6 | 29557 | 30860 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.10 | 99.46 | WP_000022832 |
| BNPCIHNK_32 | 14294 | 15304 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.54 | 99.41 | WP_002986042 |
| BNPCIHNK_14 | 7453 | 8499 | rfbB | 0.0 | Capsule | Immune modulation | 80.61 | 100.00 | WP_009659423 |
| BNPCIHNK_47 | 4807 | 6090 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.58 | 99.77 | WP_000107753 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| BNPCIHNK_11 | 22166 | 21183 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| BNPCIHNK_28 | 6669 | 7742 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| BNPCIHNK_76 | 40704 | 43007 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 92.97 | 99.22 | AAK74619 |
| BNPCIHNK_68 | 5193 | 6161 | spr0084 | 0.0 | pathogenitcity related | 92.57 | 98.48 | AAK98888 |
| BNPCIHNK_26 | 46179 | 47660 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.31 | 100.00 | ABJ54480 |
| BNPCIHNK_34 | 716 | 2962 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| BNPCIHNK_33 | 1860 | 868 | recA | 0.0 | DNA recombination and repair | 91.24 | 85.31 | AAL00560 |
| BNPCIHNK_30 | 4291 | 5262 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.12 | 100.00 | ABF36968 |
| BNPCIHNK_15 | 121159 | 120008 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.32 | 99.74 | AAL00050 |
| BNPCIHNK_15 | 85462 | 83474 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.84 | 100.00 | AE014259_2 |
| BNPCIHNK_11 | 38364 | 40094 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.87 | 100.00 | AAK34199 |
| BNPCIHNK_13 | 31320 | 29842 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.42 | 100.00 | ADE32434 |
| BNPCIHNK_6 | 29557 | 30858 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| BNPCIHNK_13 | 16131 | 14239 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| BNPCIHNK_34 | 5887 | 4178 | PGM | 0.0 | phosphoglucomutase | 84.06 | 99.65 | ACH87041 |
| BNPCIHNK_25 | 2031 | 1021 | pdh | 0.0 | pyruvate dehydrogenase | 82.79 | 99.70 | ABP91006 |
| BNPCIHNK_65 | 1512 | 151 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| BNPCIHNK_5 | 48416 | 46524 | PepO | 0.0 | endopeptidase | 80.19 | 100.00 | ABF32980 |
| BNPCIHNK_6 | 15122 | 16012 | bglB | 1.48e-179 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| BNPCIHNK_9 | 4804 | 3869 | SP_0676 | 1.73e-169 | transcription facot | 81.73 | 96.89 | AAK74821 |
| BNPCIHNK_34 | 3154 | 4011 | metF | 9.48e-167 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| BNPCIHNK_10 | 24401 | 23697 | covR | 9.58e-133 | responder protein | 85.53 | 100.00 | AAK71319 |
| BNPCIHNK_26 | 27204 | 26533 | rr01 | 2.02e-125 | response regulator | 83.93 | 99.56 | CAB54566 |
| BNPCIHNK_10 | 24401 | 23697 | walR | 4.03e-123 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| BNPCIHNK_34 | 9841 | 10509 | CiaR | 1.27e-119 | two-component response regulator | 84.31 | 99.55 | AAK74935 |
| BNPCIHNK_20 | 7669 | 6983 | CovR | 1.29e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| BNPCIHNK_34 | 9841 | 10512 | ciaR | 1.25e-117 | two component system response regulator | 82.14 | 99.12 | AIK75708 |
| BNPCIHNK_33 | 571 | 197 | SpxA2 | 8.87e-72 | transcriptional regulator | 91.20 | 94.70 | ERL21461 |
| BNPCIHNK_65 | 12876 | 13277 | SpxA1 | 1.29e-67 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| BNPCIHNK_12 | 25624 | 25337 | spr0479 | 3.00e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| BNPCIHNK_61 | 5647 | 5393 | spr1327 | 6.88e-45 | essential gene | 94.12 | 100.00 | AAL00131 |
| BNPCIHNK_17 | 9734 | 9997 | spr0175 | 1.05e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| BNPCIHNK_17 | 10561 | 10827 | spr0177 | 2.28e-34 | essential gene | 84.27 | 88.12 | AAK98981 |
| BNPCIHNK_47 | 6248 | 6748 | RopE (M5005_Spy_1611) | 2.23e-76 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| BNPCIHNK_76 | 40704 | 43001 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 82.94 | 98.08 | MYN69560 |
| BNPCIHNK_5 | 33942 | 32923 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| BNPCIHNK_5 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_6 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_7 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_8 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_9 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_10 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_11 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_12 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_13 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_14 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_15 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_16 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_17 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_18 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_19 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_20 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_21 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_22 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_23 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_24 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_25 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_26 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_27 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_28 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_29 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_30 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_31 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_32 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_33 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_34 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_35 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_36 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_37 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_38 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_39 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_40 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_41 | 1.0 | 0.0 | 1.0 |
| BNPCIHNK_42 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_43 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_44 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_45 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_46 | 1.0 | 0.0 | 1.0 |
| BNPCIHNK_47 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_48 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_49 | 1.0 | 0.0 | 1.0 |
| BNPCIHNK_50 | 1.0 | 0.0 | 1.0 |
| BNPCIHNK_51 | 1.0 | 0.0 | 1.0 |
| BNPCIHNK_52 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_53 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_54 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_55 | 1.0 | 0.0 | 1.0 |
| BNPCIHNK_61 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_65 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_68 | 0.0 | 1.0 | 0.0 |
| BNPCIHNK_76 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)