Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 24 | 34 | 41.62 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| BFBAABFN_2 | 47514 | 48974 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 96.10 | 100.00 | WP_011681177 |
| BFBAABFN_2 | 47514 | 48974 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 95.76 | 100.21 | WP_011226049 |
| BFBAABFN_15 | 135800 | 136609 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 95.19 | 100.00 | WP_002948020 |
| BFBAABFN_2 | 47514 | 48974 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 95.07 | 100.21 | WP_041827043 |
| BFBAABFN_2 | 43907 | 45274 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 94.52 | 100.00 | WP_011226045 |
| BFBAABFN_15 | 141356 | 142627 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 94.03 | 99.76 | WP_011226331 |
| BFBAABFN_2 | 43909 | 45274 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.00 | 99.85 | WP_011681173 |
| BFBAABFN_2 | 45331 | 46071 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 93.93 | 100.00 | WP_011681174 |
| BFBAABFN_15 | 143730 | 144581 | rfbD | 0.0 | Capsule | Immune modulation | 93.90 | 100.00 | WP_014621820 |
| BFBAABFN_15 | 134595 | 135800 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 93.53 | 100.00 | WP_011226326 |
| BFBAABFN_2 | 45331 | 46071 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 93.39 | 100.00 | WP_011226046 |
| BFBAABFN_2 | 45336 | 46071 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 92.94 | 98.13 | WP_011227246 |
| BFBAABFN_15 | 140395 | 141353 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 92.91 | 94.86 | WP_011226330 |
| BFBAABFN_15 | 131760 | 133544 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 92.67 | 99.94 | WP_011226325 |
| BFBAABFN_15 | 137546 | 138694 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 92.17 | 100.00 | WP_041828290 |
| BFBAABFN_2 | 46782 | 47513 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 92.08 | 100.00 | WP_011226048 |
| BFBAABFN_2 | 46782 | 47513 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 91.67 | 100.00 | WP_011681176 |
| BFBAABFN_15 | 136593 | 137549 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 91.54 | 100.00 | WP_011226328 |
| BFBAABFN_15 | 133541 | 134575 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 91.39 | 99.05 | WP_002948022 |
| BFBAABFN_46 | 18845 | 19714 | rfbA | 0.0 | Capsule | Immune modulation | 91.38 | 100.00 | WP_011681286 |
| BFBAABFN_48 | 58999 | 60657 | fbp54 | 0.0 | FBPs | Adherence | 91.15 | 99.88 | WP_011227179 |
| BFBAABFN_2 | 46782 | 47513 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 91.12 | 100.00 | WP_011227248 |
| BFBAABFN_46 | 18252 | 18845 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 90.74 | 100.00 | WP_011226149 |
| BFBAABFN_46 | 18252 | 18845 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 90.57 | 100.00 | WP_011226149 |
| BFBAABFN_46 | 18252 | 18845 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 90.57 | 100.00 | WP_011226149 |
| BFBAABFN_10 | 18715 | 19476 | cbpD | 0.0 | Autolysin | Exoenzyme | 90.29 | 90.71 | WP_011226733 |
| BFBAABFN_38 | 14705 | 15715 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 88.45 | 99.80 | WP_002986042 |
| BFBAABFN_1 | 100235 | 101538 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.24 | 99.54 | WP_000022832 |
| BFBAABFN_2 | 46081 | 46773 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 88.06 | 99.71 | WP_011227247 |
| BFBAABFN_2 | 46081 | 46773 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 88.06 | 99.71 | WP_011226047 |
| BFBAABFN_2 | 46081 | 46773 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 87.19 | 99.71 | WP_011681175 |
| BFBAABFN_33 | 118234 | 118995 | srtA | 0.0 | Sortase A | Exoenzyme | 84.67 | 99.87 | - |
| BFBAABFN_25 | 211290 | 212573 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.61 | 99.61 | WP_000107753 |
| BFBAABFN_46 | 17002 | 18048 | rfbB | 0.0 | Capsule | Immune modulation | 80.33 | 100.00 | WP_009659423 |
| BFBAABFN_2 | 34165 | 34748 | SPD_RS01775 | 2.02e-146 | Capsule | Immune modulation | 82.91 | 96.20 | WP_001819836 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| BFBAABFN_33 | 110101 | 109028 | MntE | 0.0 | manganese homeostasis | 96.09 | 99.72 | ABF32167 |
| BFBAABFN_33 | 121684 | 122667 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 96.04 | 100.00 | AAK75326 |
| BFBAABFN_38 | 137974 | 135668 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 94.54 | 99.22 | AAK74619 |
| BFBAABFN_15 | 5727 | 7208 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 93.12 | 100.00 | ABJ54480 |
| BFBAABFN_33 | 91041 | 88795 | metE | 0.0 | methionine biosynthesis enzymes | 92.52 | 100.00 | AAK74738 |
| BFBAABFN_1 | 191312 | 190344 | spr0084 | 0.0 | pathogenitcity related | 92.26 | 98.48 | AAK98888 |
| BFBAABFN_10 | 4294 | 5265 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 91.67 | 100.00 | ABF36968 |
| BFBAABFN_4 | 66170 | 72643 | PrtA | 0.0 | serine protease | 91.30 | 100.61 | ABJ55268 |
| BFBAABFN_46 | 45101 | 43371 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 89.95 | 100.00 | AAK34199 |
| BFBAABFN_15 | 186526 | 185375 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.58 | 99.74 | AAL00050 |
| BFBAABFN_15 | 158120 | 156132 | uvrB | 0.0 | excinuclease ABC, B subunit | 89.44 | 100.00 | AE014259_2 |
| BFBAABFN_6 | 25855 | 27333 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.83 | 100.00 | ADE32434 |
| BFBAABFN_1 | 101538 | 100237 | Eno | 0.0 | enolase | 86.44 | 99.77 | ABP90468 |
| BFBAABFN_6 | 41213 | 43105 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.58 | 98.90 | ABP91129 |
| BFBAABFN_33 | 85876 | 87585 | PGM | 0.0 | phosphoglucomutase | 84.76 | 99.65 | ACH87041 |
| BFBAABFN_16 | 11778 | 12869 | recA | 0.0 | DNA recombination and repair | 84.64 | 95.36 | AAL00560 |
| BFBAABFN_42 | 1647 | 2657 | pdh | 0.0 | pyruvate dehydrogenase | 83.38 | 99.70 | ABP91006 |
| BFBAABFN_48 | 45231 | 46592 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.67 | 99.56 | ABP90420 |
| BFBAABFN_1 | 115944 | 115054 | bglB | 4.61e-178 | putative phospho--glucosidase | 87.88 | 99.66 | AAK33487 |
| BFBAABFN_33 | 46708 | 47658 | SP_0676 | 3.20e-170 | transcription facot | 81.39 | 98.45 | AAK74821 |
| BFBAABFN_33 | 88608 | 87751 | metF | 4.38e-169 | methionine biosynthesis enzymes | 87.76 | 99.31 | AAK74739 |
| BFBAABFN_12 | 20914 | 20210 | covR | 9.96e-128 | responder protein | 85.53 | 100.00 | AAK71319 |
| BFBAABFN_4 | 48061 | 48732 | rr01 | 1.56e-127 | response regulator | 84.82 | 99.56 | CAB54566 |
| BFBAABFN_33 | 81909 | 81238 | ciaR | 1.67e-125 | two component system response regulator | 86.16 | 99.12 | AIK75708 |
| BFBAABFN_33 | 81909 | 81241 | CiaR | 3.08e-125 | two-component response regulator | 87.44 | 99.55 | AAK74935 |
| BFBAABFN_12 | 20914 | 20210 | walR | 2.26e-121 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| BFBAABFN_25 | 53659 | 52973 | CovR | 4.68e-120 | serves to repress GAS virulence factor-encoding genes | 81.66 | 100.00 | ACE75886 |
| BFBAABFN_16 | 13042 | 13437 | SpxA2 | 1.33e-76 | transcriptional regulator | 91.67 | 100.00 | ERL21461 |
| BFBAABFN_48 | 33733 | 33332 | SpxA1 | 1.58e-70 | transcriptional regulator | 82.84 | 100.00 | ERL19273 |
| BFBAABFN_13 | 6405 | 5992 | GrpE | 1.38e-68 | protein grpE | 81.88 | 80.59 | ABP89267 |
| BFBAABFN_25 | 30440 | 30153 | spr0479 | 4.54e-48 | essential gene | 85.42 | 98.97 | AAK99283 |
| BFBAABFN_1 | 224023 | 223769 | spr1327 | 1.69e-44 | essential gene | 92.94 | 100.00 | AAL00131 |
| BFBAABFN_42 | 92010 | 92273 | spr0175 | 6.38e-43 | pathogenitcity related | 85.23 | 100.00 | AAK98979 |
| BFBAABFN_42 | 92834 | 93100 | spr0177 | 1.42e-41 | essential gene | 83.15 | 88.12 | AAK98981 |
| BFBAABFN_25 | 211123 | 210632 | RopE (M5005_Spy_1611) | 1.04e-72 | probable DNA-directed RNA polymerase subunit delta | 82.93 | 85.86 | AAK34603 |
| BFBAABFN_38 | 137974 | 135674 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.36 | 98.08 | MYN69560 |
| BFBAABFN_42 | 39477 | 38458 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 97.35 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| BFBAABFN_1 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_2 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_4 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_6 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_8 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_9 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_10 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_11 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_12 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_13 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_14 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_15 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_16 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_19 | 1.0 | 0.0 | 1.0 |
| BFBAABFN_20 | 1.0 | 0.0 | 1.0 |
| BFBAABFN_21 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_22 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_25 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_33 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_38 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_42 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_44 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_46 | 0.0 | 1.0 | 0.0 |
| BFBAABFN_48 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)