Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 24 | 33 | 40.80 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| FCGOILMO_18 | 20640 | 21479 | cbpD | 0.0 | Autolysin | Exoenzyme | 100.00 | 100.00 | WP_011226733 |
| FCGOILMO_49 | 84708 | 86492 | STU_RS16230 | 0.0 | Capsule | Immune modulation | 99.94 | 100.00 | WP_011226325 |
| FCGOILMO_49 | 80682 | 81638 | STU_RS16250 | 0.0 | Capsule | Immune modulation | 99.79 | 100.00 | WP_011226328 |
| FCGOILMO_49 | 81622 | 82431 | STU_RS16245 | 0.0 | Capsule | Immune modulation | 99.75 | 100.00 | WP_002948020 |
| FCGOILMO_22 | 106902 | 107495 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 99.66 | 100.00 | WP_011226149 |
| FCGOILMO_49 | 82431 | 83636 | STU_RS16240 | 0.0 | Capsule | Immune modulation | 99.58 | 100.00 | WP_011226326 |
| FCGOILMO_49 | 79537 | 80685 | STU_RS16255 | 0.0 | Capsule | Immune modulation | 99.56 | 100.00 | WP_041828290 |
| FCGOILMO_22 | 106902 | 107495 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226149 |
| FCGOILMO_22 | 106902 | 107495 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 99.50 | 100.00 | WP_011226149 |
| FCGOILMO_49 | 83656 | 84711 | STU_RS16235 | 0.0 | Capsule | Immune modulation | 99.43 | 100.00 | WP_002948022 |
| FCGOILMO_49 | 75190 | 76041 | rfbD | 0.0 | Capsule | Immune modulation | 99.41 | 100.00 | WP_014621820 |
| FCGOILMO_30 | 277 | 1935 | fbp54 | 0.0 | FBPs | Adherence | 99.34 | 100.00 | WP_011227179 |
| FCGOILMO_22 | 107495 | 108364 | rfbA | 0.0 | Capsule | Immune modulation | 99.31 | 100.00 | WP_011681286 |
| FCGOILMO_49 | 78418 | 79428 | STU_RS16260 | 0.0 | Capsule | Immune modulation | 99.31 | 100.00 | WP_011226330 |
| FCGOILMO_49 | 77144 | 78418 | STU_RS16265 | 0.0 | Capsule | Immune modulation | 99.29 | 100.00 | WP_011226331 |
| FCGOILMO_22 | 52202 | 52992 | cshA | 0.0 | Cell surface hydrophobicity proteins | Adherence | 99.11 | 100.00 | - |
| FCGOILMO_22 | 142261 | 143022 | srtA | 0.0 | Sortase A | Exoenzyme | 98.42 | 100.00 | - |
| FCGOILMO_14 | 17945 | 18685 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 97.98 | 100.00 | WP_011681174 |
| FCGOILMO_14 | 19396 | 20127 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 97.95 | 100.00 | WP_011681176 |
| FCGOILMO_14 | 20128 | 21588 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 97.95 | 100.00 | WP_011681177 |
| FCGOILMO_14 | 19396 | 20127 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 97.95 | 100.00 | WP_011226048 |
| FCGOILMO_14 | 19396 | 20127 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 97.54 | 100.00 | WP_011227248 |
| FCGOILMO_14 | 17950 | 18685 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 97.28 | 98.13 | WP_011227246 |
| FCGOILMO_14 | 20128 | 21588 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 97.19 | 100.21 | WP_011226049 |
| FCGOILMO_14 | 17945 | 18685 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 97.17 | 100.00 | WP_011226046 |
| FCGOILMO_14 | 20128 | 21588 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 96.92 | 100.21 | WP_041827043 |
| FCGOILMO_14 | 16520 | 17887 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 95.69 | 100.00 | WP_011226045 |
| FCGOILMO_14 | 16522 | 17887 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.36 | 99.85 | WP_011681173 |
| FCGOILMO_14 | 18695 | 19387 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 93.51 | 100.00 | WP_011226047 |
| FCGOILMO_14 | 18695 | 19387 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 93.36 | 100.00 | WP_011227247 |
| FCGOILMO_14 | 18695 | 19387 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 88.06 | 99.71 | WP_011681175 |
| FCGOILMO_11 | 26888 | 28191 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.02 | 99.54 | WP_000022832 |
| FCGOILMO_24 | 14294 | 15304 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 86.92 | 99.51 | WP_002986042 |
| FCGOILMO_22 | 105427 | 106473 | rfbB | 0.0 | Capsule | Immune modulation | 80.52 | 100.00 | WP_009659423 |
| FCGOILMO_12 | 2301 | 3584 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.50 | 99.77 | WP_000107753 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| FCGOILMO_22 | 145709 | 146692 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 94.82 | 100.00 | AAK75326 |
| FCGOILMO_50 | 74428 | 75501 | MntE | 0.0 | manganese homeostasis | 94.41 | 99.72 | ABF32167 |
| FCGOILMO_11 | 110149 | 109181 | spr0084 | 0.0 | pathogenitcity related | 93.19 | 98.48 | AAK98888 |
| FCGOILMO_52 | 48699 | 51002 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 93.10 | 99.22 | AAK74619 |
| FCGOILMO_33 | 49491 | 50972 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 92.11 | 100.00 | ABJ54480 |
| FCGOILMO_4 | 5776 | 8022 | metE | 0.0 | methionine biosynthesis enzymes | 91.99 | 100.00 | AAK74738 |
| FCGOILMO_18 | 1850 | 852 | recA | 0.0 | DNA recombination and repair | 91.29 | 85.82 | AAL00560 |
| FCGOILMO_23 | 15489 | 14533 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 90.60 | 98.46 | ABF36968 |
| FCGOILMO_49 | 25693 | 26844 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.06 | 99.74 | AAL00050 |
| FCGOILMO_49 | 60219 | 62207 | uvrB | 0.0 | excinuclease ABC, B subunit | 88.99 | 100.00 | AE014259_2 |
| FCGOILMO_22 | 129512 | 127782 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 87.87 | 100.00 | AAK34199 |
| FCGOILMO_53 | 27018 | 28496 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.63 | 100.00 | ADE32434 |
| FCGOILMO_11 | 28191 | 26890 | Eno | 0.0 | enolase | 86.21 | 99.77 | ABP90468 |
| FCGOILMO_53 | 42213 | 44105 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 86.05 | 98.90 | ABP91129 |
| FCGOILMO_4 | 10946 | 9237 | PGM | 0.0 | phosphoglucomutase | 83.89 | 99.65 | ACH87041 |
| FCGOILMO_19 | 19069 | 20082 | pdh | 0.0 | pyruvate dehydrogenase | 83.14 | 99.70 | ABP91006 |
| FCGOILMO_9 | 32756 | 34117 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.24 | 99.56 | ABP90420 |
| FCGOILMO_1 | 48387 | 46495 | PepO | 0.0 | endopeptidase | 80.03 | 100.00 | ABF32980 |
| FCGOILMO_11 | 42631 | 41741 | bglB | 4.30e-179 | putative phospho--glucosidase | 88.55 | 99.66 | AAK33487 |
| FCGOILMO_10 | 3901 | 2963 | SP_0676 | 1.62e-169 | transcription facot | 81.47 | 97.20 | AAK74821 |
| FCGOILMO_4 | 8213 | 9070 | metF | 2.60e-166 | methionine biosynthesis enzymes | 86.36 | 99.31 | AAK74739 |
| FCGOILMO_22 | 24395 | 23691 | covR | 8.62e-132 | responder protein | 85.11 | 100.00 | AAK71319 |
| FCGOILMO_33 | 8204 | 7533 | rr01 | 2.03e-126 | response regulator | 84.38 | 99.56 | CAB54566 |
| FCGOILMO_4 | 14900 | 15568 | CiaR | 6.68e-125 | two-component response regulator | 87.00 | 99.55 | AAK74935 |
| FCGOILMO_4 | 14900 | 15571 | ciaR | 6.51e-123 | two component system response regulator | 84.82 | 99.12 | AIK75708 |
| FCGOILMO_22 | 24395 | 23691 | walR | 4.32e-122 | DNA-binding response regulator | 81.28 | 100.00 | ANC99504 |
| FCGOILMO_5 | 35060 | 35746 | CovR | 2.39e-119 | serves to repress GAS virulence factor-encoding genes | 80.79 | 100.00 | ACE75886 |
| FCGOILMO_18 | 576 | 181 | SpxA2 | 4.28e-76 | transcriptional regulator | 90.91 | 100.00 | ERL21461 |
| FCGOILMO_9 | 21536 | 21135 | SpxA1 | 7.60e-68 | transcriptional regulator | 80.60 | 100.00 | ERL19273 |
| FCGOILMO_8 | 13093 | 13380 | spr0479 | 2.95e-49 | essential gene | 86.46 | 98.97 | AAK99283 |
| FCGOILMO_11 | 144598 | 144344 | spr1327 | 2.27e-45 | essential gene | 95.29 | 100.00 | AAL00131 |
| FCGOILMO_13 | 20864 | 20601 | spr0175 | 1.69e-42 | pathogenitcity related | 84.09 | 100.00 | AAK98979 |
| FCGOILMO_13 | 20061 | 19771 | spr0177 | 9.90e-38 | essential gene | 81.00 | 98.02 | AAK98981 |
| FCGOILMO_12 | 3742 | 4242 | RopE (M5005_Spy_1611) | 9.60e-77 | probable DNA-directed RNA polymerase subunit delta | 81.44 | 87.43 | AAK34603 |
| FCGOILMO_52 | 48699 | 50996 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.07 | 98.08 | MYN69560 |
| FCGOILMO_1 | 33934 | 32915 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 96.47 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| FCGOILMO_1 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_2 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_3 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_4 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_5 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_6 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_7 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_8 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_9 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_10 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_11 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_12 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_13 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_14 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_15 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_16 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_17 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_18 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_19 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_20 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_21 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_22 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_23 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_24 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_25 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_26 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_27 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_28 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_29 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_30 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_31 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_32 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_33 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_34 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_35 | 1.0 | 0.0 | 1.0 |
| FCGOILMO_37 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_38 | 1.0 | 0.0 | 1.0 |
| FCGOILMO_39 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_40 | 1.0 | 0.0 | 1.0 |
| FCGOILMO_41 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_42 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_43 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_44 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_49 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_50 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_51 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_52 | 0.0 | 1.0 | 0.0 |
| FCGOILMO_53 | 0.0 | 1.0 | 0.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| FCGOILMO_7 | 33948 | 36551 | False | Unknown | VOG9667, VOG9405, VOG6396, VOG6396 |
Phigaro v2.4.0 (Database: Jan. 2024 release)