Probiotic potential risk score
| ARGs | VFs | PGs | PPRS |
|---|---|---|---|
| 0 | 19 | 29 | 34.67 |
PPRS is classified as low-risk (≤4), medium-risk (4-6), and high-risk (≥6).
Antibiotic resistance genes
Comprehensive Antibiotic Resistance Database (CARD)
| Query ID | Begin | End | ARO name | ARO accession | CARD name | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
RGI v6.0.3 (Database: CARD Variants v4.0.2, Nov. 2023 release)
ResFinder
| Query ID | Begin | End | Resistance gene | Phenotype | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|
| No hit found | |||||||
ResFinder v4.6.0 (Database: resfinder_db, Aug. 2024 release)
AMRFinderPlus
| Query ID | Begin | End | Gene symbol | Sequence name | Method | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
AMRFinderPlus v4.0.3 (Database: Oct. 2024 release)
Virulence factors
Virulence Factor Database (VFDB)
| Query ID | qstart | qend | Gene name | e-value | VF name | VF category | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|---|
| IFMNAIHG_1 | 605862 | 606577 | STER_RS07085 | 0.0 | Capsule | Immune modulation | 96.65 | 99.86 | WP_011681442 |
| IFMNAIHG_1 | 2090883 | 2091623 | STER_RS05305 | 0.0 | Capsule | Immune modulation | 95.01 | 100.00 | WP_011681174 |
| IFMNAIHG_1 | 606579 | 607547 | STER_RS07090 | 0.0 | Capsule | Immune modulation | 94.63 | 100.00 | WP_011681443 |
| IFMNAIHG_1 | 609887 | 610738 | rfbD | 0.0 | Capsule | Immune modulation | 94.60 | 100.00 | WP_014621820 |
| IFMNAIHG_1 | 2091680 | 2093045 | STER_RS05300 | 0.0 | Capsule | Immune modulation | 94.51 | 99.85 | WP_011681173 |
| IFMNAIHG_1 | 2087980 | 2089440 | STU_RS14650 | 0.0 | Capsule | Immune modulation | 94.11 | 100.14 | WP_011226049 |
| IFMNAIHG_1 | 2090883 | 2091623 | STU_RS14635 | 0.0 | Capsule | Immune modulation | 94.06 | 100.00 | WP_011226046 |
| IFMNAIHG_1 | 2087980 | 2089440 | STER_RS05320 | 0.0 | Capsule | Immune modulation | 93.98 | 100.00 | WP_011681177 |
| IFMNAIHG_1 | 2090883 | 2091618 | STR_RS05250 | 0.0 | Capsule | Immune modulation | 93.89 | 98.13 | WP_011227246 |
| IFMNAIHG_1 | 2091680 | 2093047 | STU_RS14630 | 0.0 | Capsule | Immune modulation | 93.79 | 100.00 | WP_011226045 |
| IFMNAIHG_1 | 2087980 | 2089440 | STR_RS05265 | 0.0 | Capsule | Immune modulation | 93.22 | 100.14 | WP_041827043 |
| IFMNAIHG_1 | 604740 | 605516 | STER_RS07075 | 0.0 | Capsule | Immune modulation | 92.66 | 100.00 | WP_011681440 |
| IFMNAIHG_1 | 608515 | 609768 | STER_RS07100 | 0.0 | Capsule | Immune modulation | 92.35 | 99.52 | WP_011681445 |
| IFMNAIHG_1 | 2089441 | 2090172 | STU_RS14645 | 0.0 | Capsule | Immune modulation | 92.21 | 100.00 | WP_011226048 |
| IFMNAIHG_1 | 1915560 | 1916153 | STR_RS05880 | 0.0 | Capsule | Immune modulation | 92.09 | 100.00 | WP_011226149 |
| IFMNAIHG_1 | 1915560 | 1916153 | STER_RS06030 | 0.0 | Capsule | Immune modulation | 91.92 | 100.00 | WP_011226149 |
| IFMNAIHG_1 | 1915560 | 1916153 | STU_RS15260 | 0.0 | Capsule | Immune modulation | 91.92 | 100.00 | WP_011226149 |
| IFMNAIHG_1 | 2089441 | 2090172 | STER_RS05315 | 0.0 | Capsule | Immune modulation | 91.53 | 100.00 | WP_011681176 |
| IFMNAIHG_1 | 1161372 | 1162211 | cbpD | 0.0 | Autolysin | Exoenzyme | 91.43 | 100.00 | WP_011226733 |
| IFMNAIHG_1 | 1914691 | 1915560 | rfbA | 0.0 | Capsule | Immune modulation | 91.26 | 100.00 | WP_011681286 |
| IFMNAIHG_1 | 2089441 | 2090172 | STR_RS05260 | 0.0 | Capsule | Immune modulation | 91.26 | 100.00 | WP_011227248 |
| IFMNAIHG_1 | 99794 | 101452 | fbp54 | 0.0 | FBPs | Adherence | 90.90 | 99.94 | WP_011227179 |
| IFMNAIHG_1 | 911841 | 912851 | plr/gapA | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | 88.45 | 99.80 | WP_002986042 |
| IFMNAIHG_1 | 1734724 | 1736027 | eno | 0.0 | Streptococcal enolase | Exoenzyme | 88.24 | 99.54 | WP_000022832 |
| IFMNAIHG_1 | 2090181 | 2090873 | STR_RS05255 | 0.0 | Capsule | Immune modulation | 88.18 | 99.86 | WP_011227247 |
| IFMNAIHG_1 | 2090181 | 2090873 | STU_RS14640 | 0.0 | Capsule | Immune modulation | 88.18 | 99.86 | WP_011226047 |
| IFMNAIHG_1 | 2090181 | 2090873 | STER_RS05310 | 0.0 | Capsule | Immune modulation | 86.89 | 99.86 | WP_011681175 |
| IFMNAIHG_1 | 244587 | 245348 | srtA | 0.0 | Sortase A | Exoenzyme | 84.03 | 99.74 | - |
| IFMNAIHG_1 | 1916356 | 1917402 | rfbB | 0.0 | Capsule | Immune modulation | 81.22 | 99.90 | WP_009659423 |
| IFMNAIHG_1 | 1245191 | 1246474 | tig/ropA | 0.0 | Trigger factor | Stress survival | 80.84 | 99.61 | WP_000107753 |
BLASTN v2.16.0 (Database: VFDB, Dec. 2024 release)
VirulenceFinder
| Query ID | Begin | End | Database | Virulence factor | Protein function | Identity | Coverage | Accession no. |
|---|---|---|---|---|---|---|---|---|
| No hit found | ||||||||
VirulenceFinder v2.0. 4 (Database: virulencefinder_db, Feb . 2024 release)
Pathogenic genes
PHI-base
| Query ID | qstart | qend | Gene name | e-value | Function | Identity | Coverage | Gene ID |
|---|---|---|---|---|---|---|---|---|
| IFMNAIHG_1 | 248036 | 249019 | ldh(Sp_1220) | 0.0 | L-lactate dehydrogenase | 96.34 | 100.00 | AAK75326 |
| IFMNAIHG_1 | 236453 | 235380 | MntE | 0.0 | manganese homeostasis | 95.53 | 99.72 | ABF32167 |
| IFMNAIHG_1 | 784929 | 787235 | pfl2(Sp_0459) | 0.0 | formate acetyltransferase | 94.41 | 99.22 | AAK74619 |
| IFMNAIHG_1 | 366545 | 368026 | SPD_0310 | 0.0 | UPF0371 protein SPD_0310 | 93.32 | 100.00 | ABJ54480 |
| IFMNAIHG_1 | 215974 | 213728 | metE | 0.0 | methionine biosynthesis enzymes | 93.06 | 100.00 | AAK74738 |
| IFMNAIHG_1 | 1644283 | 1645251 | spr0084 | 0.0 | pathogenitcity related | 92.88 | 98.48 | AAK98888 |
| IFMNAIHG_1 | 1145394 | 1146365 | prsA2 | 0.0 | ribose-phosphate pyrophosphokinase | 91.67 | 100.00 | ABF36968 |
| IFMNAIHG_1 | 1889307 | 1891037 | ptsI | 0.0 | phosphoenolpyruvate-protein phosphotransferase | 89.95 | 100.00 | AAK34199 |
| IFMNAIHG_1 | 624170 | 622182 | uvrB | 0.0 | excinuclease ABC, B subunit | 89.59 | 100.00 | AE014259_2 |
| IFMNAIHG_1 | 652526 | 651375 | potA | 0.0 | ABC transporter ATP-binding protein-spermidine/putrescine transport | 89.58 | 99.74 | AAL00050 |
| IFMNAIHG_1 | 1109886 | 1108408 | IMPDH | 0.0 | inosine-5'-monophosphate dehydrogenase | 87.83 | 100.00 | ADE32434 |
| IFMNAIHG_1 | 1734724 | 1736025 | Eno | 0.0 | enolase | 86.44 | 99.77 | ABP90468 |
| IFMNAIHG_1 | 1094532 | 1092640 | gidA | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | 85.58 | 98.90 | ABP91129 |
| IFMNAIHG_1 | 210806 | 212515 | PGM | 0.0 | phosphoglucomutase | 84.76 | 99.65 | ACH87041 |
| IFMNAIHG_1 | 1182986 | 1184077 | recA | 0.0 | DNA recombination and repair | 84.64 | 95.36 | AAL00560 |
| IFMNAIHG_1 | 967455 | 968465 | pdh | 0.0 | pyruvate dehydrogenase | 83.38 | 99.70 | ABP91006 |
| IFMNAIHG_1 | 86029 | 87390 | mnmE | 0.0 | central tRNA-modifying GTPase | 82.46 | 99.56 | ABP90420 |
| IFMNAIHG_1 | 1720315 | 1721205 | bglB | 1.20e-176 | putative phospho--glucosidase | 87.54 | 99.66 | AAK33487 |
| IFMNAIHG_1 | 171551 | 172501 | SP_0676 | 2.98e-169 | transcription facot | 81.39 | 98.45 | AAK74821 |
| IFMNAIHG_1 | 213538 | 212681 | metF | 9.10e-168 | methionine biosynthesis enzymes | 87.06 | 99.31 | AAK74739 |
| IFMNAIHG_1 | 2042309 | 2043013 | covR | 9.35e-126 | responder protein | 85.53 | 100.00 | AAK71319 |
| IFMNAIHG_1 | 311912 | 311241 | rr01 | 1.47e-125 | response regulator | 84.38 | 99.56 | CAB54566 |
| IFMNAIHG_1 | 206840 | 206169 | ciaR | 1.51e-125 | two component system response regulator | 86.61 | 99.12 | AIK75708 |
| IFMNAIHG_1 | 206840 | 206178 | CiaR | 5.97e-124 | two-component response regulator | 88.23 | 98.66 | AAK74935 |
| IFMNAIHG_1 | 2042309 | 2043013 | walR | 2.13e-119 | DNA-binding response regulator | 82.13 | 100.00 | ANC99504 |
| IFMNAIHG_1 | 1402866 | 1403552 | CovR | 4.59e-119 | serves to repress GAS virulence factor-encoding genes | 81.66 | 100.00 | ACE75886 |
| IFMNAIHG_1 | 1184251 | 1184646 | SpxA2 | 2.07e-74 | transcriptional regulator | 91.67 | 100.00 | ERL21461 |
| IFMNAIHG_1 | 74563 | 74162 | SpxA1 | 2.32e-68 | transcriptional regulator | 82.09 | 100.00 | ERL19273 |
| IFMNAIHG_1 | 1231571 | 1231984 | GrpE | 1.63e-66 | protein grpE | 81.88 | 80.59 | ABP89267 |
| IFMNAIHG_1 | 1246641 | 1247132 | RopE (M5005_Spy_1611) | 1.02e-71 | probable DNA-directed RNA polymerase subunit delta | 82.93 | 85.86 | AAK34603 |
| IFMNAIHG_1 | 784929 | 787229 | PFL (B9H01_RS01125) | 0.0 | formate C-acetyltransferase | 83.09 | 98.08 | MYN69560 |
| IFMNAIHG_1 | 1003894 | 1002875 | ilvC (SPD_0406) | 0.0 | ketol-acid reductoisomerase (NADP(+)) | 97.35 | 100.00 | ABJ55451 |
BLASTX v2.16.0 (Database: PHI base v4.16, May. 2024 release)
Plasmid
PlasmidFinder
| Query ID | Begin | End | Plasmid | Query / Template | Identity | Accession no. |
|---|---|---|---|---|---|---|
| No hit found | ||||||
PlasmidFinder v 2.1.6 (Database: plasmidfinder_db v 2.2.0 , Nov. 2024 release)
PlasmidHunter
| Query ID | Prediction | Chromosome | Plasmid |
|---|---|---|---|
| IFMNAIHG_1 | 0.0 | 1.0 | 0.0 |
| IFMNAIHG_2 | 1.0 | 0.0 | 1.0 |
PlasmidHunter v 1.4.5 (Database: May. 2024 release)
Prophage
Phigaro
| Query ID | Begin | End | Transposable | Taxonomy | pVOGs |
|---|---|---|---|---|---|
| No hit found | |||||
Phigaro v2.4.0 (Database: Jan. 2024 release)